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Gene: IDS (iduronate 2-sulfatase) Homo sapiens
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Symbol: IDS
Name: iduronate 2-sulfatase
Description: Exhibits calcium ion binding activity and iduronate-2-sulfatase activity. Involved in glycosaminoglycan catabolic process. Localizes to the lysosome. Implicated in mucopolysaccharidosis II.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: alpha-L-iduronate sulfate sulfatase; ID2S; iduronate 2-sulfatase 14 kDa chain; iduronate 2-sulfatase 42 kDa chain; idursulfase; MPS2; SIDS
Orthologs:
Mus musculus (house mouse) : Ids (iduronate 2-sulfatase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ids (iduronate 2-sulfatase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ids (iduronate 2-sulfatase)
Pan paniscus (bonobo/pygmy chimpanzee) : IDS (iduronate 2-sulfatase)
Canis lupus familiaris (dog) : IDS (iduronate 2-sulfatase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ids (iduronate 2-sulfatase)
Sus scrofa (pig) : IDS (iduronate 2-sulfatase)
Chlorocebus sabaeus (African green monkey) : IDS (iduronate 2-sulfatase)
Heterocephalus glaber (naked mole-rat) : Ids (iduronate 2-sulfatase)
more info ...
Related Pseudogenes: IDSP1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 EnsemblX149,477,104 - 149,540,926 (-)Ensembl
GRCh38 EnsemblX149,476,988 - 149,521,096 (-)Ensembl
GRCh38X149,476,988 - 149,505,306 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X148,560,295 - 148,586,884 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X148,368,206 - 148,394,698 (-)NCBINCBI36hg18NCBI36
Build 34X148,274,422 - 148,292,552NCBI
CeleraX148,909,049 - 148,935,639 (-)NCBI
Cytogenetic MapXq28NCBI
HuRefX137,513,419 - 137,540,564 (-)NCBIHuRef
CHM1_1X148,519,548 - 148,547,912 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on IDS
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1351665
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.