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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:niclosamide
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Accession:CHEBI:7553 term browser browse the term
Definition:A secondary carboxamide resulting from the formal condensation of the carboxy group of 5-chlorosalicylic acid with the amino group of 2-chloro-4-nitroaniline. It is an oral anthelmintic drug approved for use against tapeworm infections.
Synonyms:exact_synonym: 5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide
 related_synonym: 2',5-dichloro-2-hydroxy-4'-nitrobenzanilide;   2',5-dichloro-4'-nitrosalicylanilide;   2-chloro-4-nitrophenylamide-6-chlorosalicylic acid;   2-hydroxy-5-chloro-N-(2-chloro-4-nitrophenyl)benzamide;   5-chloro-2'-chloro-4'-nitrosalicylanilide;   5-chloro-N-(2'-chloro-4'-nitrophenyl)salicylamide;   Atenase;   B 2353;   BAY 2353;   Bayer 2353;   Bayer 73;   Bayluscide;   Cestocid;   Devermin;   Devermine;   Fedal-Telmin;   Fenasal;   Formula=C13H8Cl2N2O4;   HL 2447;   Helmiantin;   InChI=1S/C13H8Cl2N2O4/c14-7-1-4-12(18)9(5-7)13(19)16-11-3-2-8(17(20)21)6-10(11)15/h1-6,18H,(H,16,19);   InChIKey=RJMUSRYZPJIFPJ-UHFFFAOYSA-N;   Iomesan;   Lintex;   Mansonil;   Mato;   N-(2-chloro-4-nitrophenyl)-5-chlorosalicylamide;   Nasemo;   Phenasal;   Radeverm;   SMILES=OC1=CC=C(Cl)C=C1C(=O)NC1=C(Cl)C=C(C=C1)[N+]([O-])=O;   Sagimid;   Sulqui;   Tredemine;   Utosamide;   Vermitid;   Vermitin;   WR 46234;   Yomesan;   Zestocarp;   clonitralide;   niclocide;   niclosamida;   niclosamidum
 alt_id: CHEBI:92630
 xref: CAS:50-65-7;   Chemspider:4322;   DrugBank:DB06803;   Drug_Central:1912;   HMDB:HMDB0015679;   KEGG:D00436;   LINCS:LSM-2787
 xref_mesh: MESH:D009534
 xref: PMCID:PMC8308039;   PMCID:PMC8508655;   PMID:24900231;   PMID:33325188;   PMID:33772737;   PMID:33855343;   PMID:33860549;   PMID:33870260;   PMID:34038481;   PMID:34209118;   PMID:34332199;   PMID:34386088;   PMID:34429248;   PMID:34482191;   PMID:34483712;   PMID:34512959;   PMID:34517104;   PMID:34572856;   PMID:34638761;   PPDB:1929;   Pesticides:niclosamide;   Reaxys:2820605;   VSDB:1929;   Wikipedia:Niclosamide


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niclosamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A1bg alpha-1-B glycoprotein increases expression ISO Niclosamide results in increased expression of A1BG mRNA CTD PMID:36318118 NCBI chr 7:92,493,934...92,498,460
Ensembl chr 7:92,494,372...92,498,097 		JBrowse link
G Abca12 ATP binding cassette subfamily A member 12 decreases expression ISO Niclosamide results in decreased expression of ABCA12 mRNA CTD PMID:36318118 NCBI chr 9:72,822,661...72,995,748
Ensembl chr 9:72,823,350...72,996,049 		JBrowse link
G Abcc9 ATP binding cassette subfamily C member 9 decreases expression ISO Niclosamide results in decreased expression of ABCC9 mRNA CTD PMID:36318118 NCBI chr 4:175,531,854...175,655,849
Ensembl chr 4:175,532,547...175,655,356 		JBrowse link
G Abcg4 ATP binding cassette subfamily G member 4 increases expression ISO Niclosamide results in increased expression of ABCG4 mRNA CTD PMID:36318118 NCBI chr 8:44,611,187...44,629,818
Ensembl chr 8:44,611,187...44,626,881 		JBrowse link
G Abhd1 abhydrolase domain containing 1 increases expression ISO Niclosamide results in increased expression of ABHD1 mRNA CTD PMID:36318118 NCBI chr 6:25,422,526...25,427,514
Ensembl chr 6:25,422,526...25,427,514 		JBrowse link
G Abhd14b abhydrolase domain containing 14b increases expression ISO Niclosamide results in increased expression of ABHD14B mRNA CTD PMID:36318118 NCBI chr 8:107,087,157...107,092,122
Ensembl chr 8:107,088,069...107,092,119 		JBrowse link
G Acaca acetyl-CoA carboxylase alpha decreases expression ISO Niclosamide results in decreased expression of ACACA mRNA CTD PMID:22576131 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457 		JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant multiple interactions ISO Niclosamide inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 mRNA]
Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of ACP5 mRNA]		 CTD PMID:26792726 PMID:28824321 NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929 		JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 decreases expression ISO Niclosamide results in decreased expression of ACSL1 mRNA CTD PMID:22576131 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541 		JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions
decreases expression		 ISO Niclosamide inhibits the reaction [Doxorubicin results in increased expression of ACTA2 protein]
CTNNB1 protein inhibits the reaction [Niclosamide results in decreased expression of ACTA2 protein]; Niclosamide inhibits the reaction [[Lapatinib results in decreased susceptibility to Lapatinib] which results in increased expression of ACTA2 protein]; Niclosamide inhibits the reaction [TGFB1 protein results in increased phosphorylation of ACTA2 protein]		 CTD PMID:26643609 PMID:28318631 PMID:35115509 PMID:36870549 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Adamts17 ADAM metallopeptidase with thrombospondin type 1 motif, 17 decreases expression ISO Niclosamide results in decreased expression of ADAMTS17 mRNA CTD PMID:36318118 NCBI chr 1:120,445,800...120,768,204
Ensembl chr 1:120,445,749...120,768,202 		JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide decreases expression ISO Niclosamide results in decreased expression of ADH4 mRNA CTD PMID:28284560 NCBI chr 2:226,948,717...226,966,747
Ensembl chr 2:226,947,466...226,987,591 		JBrowse link
G Adm2 adrenomedullin 2 increases expression ISO Niclosamide results in increased expression of ADM2 mRNA CTD PMID:36318118 NCBI chr 7:120,393,179...120,394,965
Ensembl chr 7:120,393,179...120,396,331 		JBrowse link
G Adra2a adrenoceptor alpha 2A decreases expression ISO Niclosamide results in decreased expression of ADRA2A mRNA CTD PMID:36318118 NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365 		JBrowse link
G Afp alpha-fetoprotein multiple interactions EXP Niclosamide inhibits the reaction [Thioacetamide results in increased expression of AFP protein]; Poloxamer promotes the reaction [Niclosamide inhibits the reaction [Thioacetamide results in increased expression of AFP protein]] CTD PMID:32961231 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480 		JBrowse link
G Agbl3 AGBL carboxypeptidase 3 decreases expression ISO Niclosamide results in decreased expression of AGBL3 mRNA CTD PMID:36318118 NCBI chr 4:63,448,789...63,535,538
Ensembl chr 4:63,453,940...63,531,188 		JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 increases cleavage ISO Niclosamide results in increased cleavage of AIFM1 protein CTD PMID:22576131 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256 		JBrowse link
G Akna AT-hook transcription factor increases expression ISO Niclosamide results in increased expression of AKNA mRNA CTD PMID:36318118 NCBI chr 5:76,777,415...76,824,380
Ensembl chr 5:76,777,415...76,816,017 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases expression
multiple interactions		 ISO Niclosamide results in increased expression of AKT1 mRNA
Niclosamide inhibits the reaction [TNF protein results in increased activity of AKT1 protein]; Niclosamide inhibits the reaction [TNFSF11 protein results in increased phosphorylation of AKT1 protein]		 CTD PMID:20215516 PMID:26792726 PMID:29843133 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 decreases expression ISO Niclosamide results in decreased expression of ALDH1A1 protein CTD PMID:24736023 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961 		JBrowse link
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 increases expression ISO Niclosamide results in increased expression of ALDH6A1 mRNA CTD PMID:36318118 NCBI chr 6:104,077,975...104,098,636
Ensembl chr 6:104,077,979...104,098,656 		JBrowse link
G Aldob aldolase, fructose-bisphosphate B increases expression ISO Niclosamide results in increased expression of ALDOB mRNA CTD PMID:22576131 NCBI chr 5:63,889,045...63,902,086
Ensembl chr 5:63,889,046...63,902,116 		JBrowse link
G Aldoc aldolase, fructose-bisphosphate C decreases expression
increases expression		 ISO Niclosamide results in decreased expression of ALDOC mRNA
Niclosamide results in increased expression of ALDOC mRNA		 CTD PMID:22576131 PMID:36318118 NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066 		JBrowse link
G Alkbh7 alkB homolog 7 increases expression ISO Niclosamide results in increased expression of ALKBH7 mRNA CTD PMID:36318118 NCBI chr 9:1,838,886...1,841,044
Ensembl chr 9:1,838,811...1,841,044 		JBrowse link
G Alox12b arachidonate 12-lipoxygenase, 12R type increases expression
decreases response to substance
multiple interactions		 ISO Niclosamide results in increased expression of ALOX12B mRNA
ALOX12B protein results in decreased susceptibility to Niclosamide
TP53 gene mutant form inhibits the reaction [Niclosamide results in increased expression of ALOX12B mRNA]; TP53 protein mutant form inhibits the reaction [Niclosamide results in increased expression of ALOX12B mRNA]		 CTD PMID:30258081 NCBI chr10:53,863,060...53,874,938
Ensembl chr10:53,863,060...53,874,938 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase multiple interactions
increases expression
decreases response to substance		 ISO TP53 gene mutant form inhibits the reaction [Niclosamide results in increased expression of ALOX5 mRNA]; TP53 protein mutant form inhibits the reaction [Niclosamide results in increased expression of ALOX5 mRNA]
ALOX5 protein results in decreased susceptibility to Niclosamide		 CTD PMID:30258081 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743 		JBrowse link
G Alpl alkaline phosphatase, biomineralization associated decreases expression ISO Niclosamide results in decreased expression of ALPL mRNA CTD PMID:28824321 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446 		JBrowse link
G Amhr2 anti-Mullerian hormone receptor type 2 increases expression ISO Niclosamide results in increased expression of AMHR2 mRNA CTD PMID:36318118 NCBI chr 7:133,579,152...133,588,874
Ensembl chr 7:133,579,393...133,588,258 		JBrowse link
G Amot angiomotin increases expression ISO Niclosamide results in increased expression of AMOT mRNA CTD PMID:36318118 NCBI chr  X:108,982,399...109,041,265
Ensembl chr  X:108,984,022...109,041,272 		JBrowse link
G Ank3 ankyrin 3 increases expression ISO Niclosamide results in increased expression of ANK3 mRNA CTD PMID:36318118 NCBI chr20:18,602,267...19,225,831
Ensembl chr20:18,602,786...19,086,300 		JBrowse link
G Ankmy2 ankyrin repeat and MYND domain containing 2 increases expression ISO Niclosamide results in increased expression of ANKMY2 mRNA CTD PMID:36318118 NCBI chr 6:52,888,959...52,930,343
Ensembl chr 6:52,888,963...52,930,394 		JBrowse link
G Ankrd12 ankyrin repeat domain 12 increases expression ISO Niclosamide results in increased expression of ANKRD12 mRNA CTD PMID:36318118 NCBI chr 9:105,583,273...105,687,957
Ensembl chr 9:105,584,065...105,687,911 		JBrowse link
G Ankrd34a ankyrin repeat domain 34A increases expression ISO Niclosamide results in increased expression of ANKRD34A mRNA CTD PMID:36318118 NCBI chr 2:184,129,830...184,135,075
Ensembl chr 2:184,129,238...184,135,116 		JBrowse link
G Anxa4 annexin A4 increases expression ISO Niclosamide results in increased expression of ANXA4 mRNA CTD PMID:36318118 NCBI chr 4:119,184,378...119,241,183
Ensembl chr 4:119,184,374...119,241,161 		JBrowse link
G Ap1s3 adaptor related protein complex 1 subunit sigma 3 decreases expression ISO Niclosamide results in decreased expression of AP1S3 mRNA CTD PMID:36318118 NCBI chr 9:80,950,402...81,009,889
Ensembl chr 9:80,950,715...81,009,798 		JBrowse link
G Aplnr apelin receptor decreases expression ISO Niclosamide results in decreased expression of APLNR mRNA CTD PMID:36318118 NCBI chr 3:70,217,407...70,221,052
Ensembl chr 3:70,217,385...70,221,050 		JBrowse link
G Apof apolipoprotein F decreases expression ISO Niclosamide results in decreased expression of APOF mRNA CTD PMID:28284560 NCBI chr 7:700,688...702,130
Ensembl chr 7:700,762...701,946 		JBrowse link
G Ar androgen receptor multiple interactions
decreases expression		 ISO [enzalutamide co-treated with Niclosamide] results in decreased expression of AR protein; [Niclosamide inhibits the reaction [AR protein binds to KLK3 promoter]] which results in decreased expression of KLK3 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Niclosamide results in decreased expression of and results in increased degradation of AR protein alternative form]; bicalutamide promotes the reaction [Niclosamide inhibits the reaction [AR protein binds to KLK3 promoter]]; bicalutamide promotes the reaction [Niclosamide results in decreased expression of AR protein alternative form]; bicalutamide promotes the reaction [Niclosamide results in decreased expression of AR protein]; Niclosamide inhibits the reaction [AR protein alternative form binds to KLK3 promoter]; Niclosamide inhibits the reaction [AR protein alternative form results in decreased susceptibility to enzalutamide]; Niclosamide inhibits the reaction [AR protein alternative form results in increased expression of KLK3 mRNA]; Niclosamide inhibits the reaction [AR protein alternative form results in increased expression of KLK3 protein]; Niclosamide inhibits the reaction [AR protein binds to KLK3 promoter]; Niclosamide inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA]; Niclosamide results in decreased expression of and results in increased degradation of AR protein alternative form
Niclosamide results in decreased expression of AR protein; Niclosamide results in decreased expression of AR protein alternative form		 CTD PMID:24740322 PMID:25970160 PMID:28500234 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Araf A-Raf proto-oncogene, serine/threonine kinase decreases expression ISO Niclosamide analog results in decreased expression of ARAF protein; Niclosamide results in decreased expression of ARAF protein CTD PMID:28284560 NCBI chr  X:1,227,392...1,292,356
Ensembl chr  X:1,227,392...1,239,073 		JBrowse link
G Arhgdib Rho GDP dissociation inhibitor beta increases expression ISO Niclosamide results in increased expression of ARHGDIB mRNA CTD PMID:36318118 NCBI chr 4:169,822,951...169,841,884
Ensembl chr 4:169,822,952...169,841,658 		JBrowse link
G Armcx1 armadillo repeat containing, X-linked 1 increases expression ISO Niclosamide results in increased expression of ARMCX1 mRNA CTD PMID:36318118 NCBI chr  X:97,898,969...97,902,874
Ensembl chr  X:97,898,883...97,903,299 		JBrowse link
G Arrdc2 arrestin domain containing 2 increases expression ISO Niclosamide results in increased expression of ARRDC2 mRNA CTD PMID:36318118 NCBI chr16:18,601,897...18,606,029
Ensembl chr16:18,601,897...18,606,029 		JBrowse link
G Asf1b anti-silencing function 1B histone chaperone decreases expression ISO Niclosamide results in decreased expression of ASF1B mRNA CTD PMID:28284560 NCBI chr19:24,181,024...24,195,604
Ensembl chr19:24,181,028...24,195,549 		JBrowse link
G Atcay ATCAY kinesin light chain interacting caytaxin increases expression ISO Niclosamide results in increased expression of ATCAY mRNA CTD PMID:36318118 NCBI chr 7:8,487,763...8,511,527
Ensembl chr 7:8,487,763...8,512,663 		JBrowse link
G Atf3 activating transcription factor 3 increases expression
multiple interactions		 ISO Niclosamide results in increased expression of ATF3 mRNA; Niclosamide results in increased expression of ATF3 protein
ATF3 protein affects the reaction [Niclosamide results in increased cleavage of CASP3 protein]; ATF3 protein affects the reaction [Niclosamide results in increased expression of DDIT3 mRNA]; ATF3 protein affects the reaction [Niclosamide results in increased expression of EIF2AK3 mRNA]		 CTD PMID:26917416 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Atf4 activating transcription factor 4 increases expression ISO Niclosamide results in increased expression of ATF4 mRNA; Niclosamide results in increased expression of ATF4 protein CTD PMID:26917416 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446 		JBrowse link
G Atosb atos homolog B increases expression ISO Niclosamide results in increased expression of ATOSB mRNA CTD PMID:36318118 NCBI chr 5:57,260,839...57,274,524
Ensembl chr 5:57,260,841...57,268,892 		JBrowse link
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 increases expression ISO Niclosamide results in increased expression of ATP2A3 mRNA CTD PMID:36318118 NCBI chr10:57,581,742...57,612,758
Ensembl chr10:57,582,128...57,612,748 		JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha increases expression ISO Niclosamide results in increased expression of ATP5F1A mRNA CTD PMID:22576131 NCBI chr18:71,292,406...71,300,342
Ensembl chr18:71,292,374...71,300,794 		JBrowse link
G Atp5f1d ATP synthase F1 subunit delta increases expression ISO Niclosamide results in increased expression of ATP5F1D mRNA CTD PMID:22576131 NCBI chr 7:9,560,604...9,565,919
Ensembl chr 7:9,560,608...9,565,929 		JBrowse link
G Atp5mc3 ATP synthase membrane subunit c locus 3 decreases expression ISO Niclosamide results in decreased expression of ATP5MC3 mRNA CTD PMID:22576131 NCBI chr 3:58,810,535...58,813,185
Ensembl chr 3:58,810,535...58,814,279 		JBrowse link
G Atp5mf ATP synthase membrane subunit f decreases expression ISO Niclosamide results in decreased expression of ATP5MF mRNA CTD PMID:22576131 NCBI chr12:9,421,665...9,428,236
Ensembl chr12:9,421,579...9,428,236 		JBrowse link
G Atp5mg ATP synthase membrane subunit G decreases expression ISO Niclosamide results in decreased expression of ATP5MG mRNA CTD PMID:22576131 NCBI chr 8:45,225,680...45,233,630
Ensembl chr 8:45,225,686...45,233,559 		JBrowse link
G Atp5pb ATP synthase peripheral stalk-membrane subunit b decreases expression ISO Niclosamide results in decreased expression of ATP5PB mRNA CTD PMID:22576131 NCBI chr 2:193,424,138...193,435,418
Ensembl chr 2:193,424,047...193,435,418 		JBrowse link
G Atp6ap1 ATPase H+ transporting accessory protein 1 decreases expression ISO Niclosamide results in decreased expression of ATP6AP1 mRNA CTD PMID:22576131 NCBI chr  X:152,079,954...152,087,034
Ensembl chr  X:152,079,865...152,087,034 		JBrowse link
G Atp6v0d2 ATPase H+ transporting V0 subunit D2 multiple interactions ISO Niclosamide inhibits the reaction [TNFSF11 protein results in increased expression of ATP6V0D2 mRNA] CTD PMID:26792726 NCBI chr 5:33,336,257...33,385,354
Ensembl chr 5:33,336,264...33,385,354 		JBrowse link
G Atpsckmt ATP synthase c subunit lysine N-methyltransferase decreases expression ISO Niclosamide results in decreased expression of ATPSCKMT mRNA CTD PMID:36318118 NCBI chr 2:82,603,086...82,618,325
Ensembl chr 2:82,603,009...82,618,308 		JBrowse link
G Aurkb aurora kinase B decreases expression ISO Niclosamide results in decreased expression of AURKB mRNA CTD PMID:28284560 NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837 		JBrowse link
G Avpi1 arginine vasopressin-induced 1 increases expression ISO Niclosamide results in increased expression of AVPI1 mRNA CTD PMID:36318118 NCBI chr 1:240,930,236...240,936,154
Ensembl chr 1:240,930,236...240,936,154 		JBrowse link
G Axin2 axin 2 multiple interactions
decreases expression		 ISO Niclosamide inhibits the reaction [Lithium Chloride results in increased expression of AXIN2 mRNA]
Niclosamide results in decreased expression of AXIN2 mRNA; Niclosamide results in decreased expression of AXIN2 protein		 CTD PMID:22576131 PMID:24534281 PMID:24552774 PMID:24736023 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231 		JBrowse link
G B3gnt7 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 increases expression ISO Niclosamide results in increased expression of B3GNT7 mRNA CTD PMID:36318118 NCBI chr 9:86,956,220...86,960,171
Ensembl chr 9:86,956,220...86,960,170 		JBrowse link
G B3gnt9 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 increases expression ISO Niclosamide results in increased expression of B3GNT9 mRNA CTD PMID:36318118 NCBI chr19:33,129,740...33,134,048
Ensembl chr19:33,128,142...33,132,344 		JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions ISO [Niclosamide binds to Polyethyleneimine] which results in increased expression of BAD mRNA CTD PMID:25988281 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions ISO [Niclosamide binds to Polyethyleneimine] which results in increased expression of BAK1 mRNA CTD PMID:25988281 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
decreases expression
multiple interactions		 ISO Niclosamide results in increased expression of BAX protein
Niclosamide results in decreased expression of BAX protein
[Niclosamide binds to Polyethyleneimine] which results in increased expression of BAX mRNA; [Niclosamide co-treated with bicalutamide] results in increased expression of BAX protein; bicalutamide inhibits the reaction [Niclosamide results in decreased expression of BAX protein]		 CTD PMID:25634333 PMID:25988281 PMID:26703449 PMID:28500234 PMID:35115509 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bbc3 Bcl-2 binding component 3 multiple interactions
increases expression		 ISO TP53 gene mutant form inhibits the reaction [Niclosamide results in increased expression of BBC3 mRNA] CTD PMID:30258081 PMID:36318118 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509 		JBrowse link
G Bbs2 Bardet-Biedl syndrome 2 increases expression ISO Niclosamide results in increased expression of BBS2 mRNA CTD PMID:36318118 NCBI chr19:10,909,653...10,944,998
Ensembl chr19:10,909,619...10,944,993 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions		 ISO Niclosamide analog results in decreased expression of BCL2 protein; Niclosamide results in decreased expression of BCL2 protein
[Niclosamide binds to Polyethyleneimine] which results in decreased expression of BCL2 mRNA; [Niclosamide inhibits the reaction [Erlotinib Hydrochloride results in increased expression of BCL2 protein]] which results in increased susceptibility to Erlotinib Hydrochloride; bicalutamide promotes the reaction [Niclosamide results in decreased expression of BCL2 protein]; Niclosamide inhibits the reaction [Erlotinib Hydrochloride results in increased expression of BCL2 protein]; Niclosamide inhibits the reaction [TNF protein results in increased expression of BCL2 mRNA]; Niclosamide promotes the reaction [bicalutamide results in decreased expression of BCL2 protein]		 CTD PMID:20215516 PMID:23894143 PMID:25634333 PMID:25988281 PMID:26116531 More... NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
decreases expression		 ISO [Niclosamide binds to Polyethyleneimine] which results in decreased expression of BCL2L1 mRNA; bicalutamide promotes the reaction [Niclosamide results in decreased expression of BCL2L1 protein]; Niclosamide inhibits the reaction [TNF protein results in increased expression of BCL2L1 mRNA]; Niclosamide promotes the reaction [bicalutamide results in decreased expression of BCL2L1 protein]
Niclosamide analog results in decreased expression of BCL2L1 protein; Niclosamide results in decreased expression of BCL2L1 protein		 CTD PMID:20215516 PMID:25988281 PMID:26116531 PMID:28284560 PMID:28500234 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Bcl2l2 Bcl2-like 2 decreases expression
multiple interactions		 ISO Niclosamide results in decreased expression of BCL2L2 protein
[Niclosamide inhibits the reaction [Erlotinib Hydrochloride results in increased expression of BCL2L2 protein]] which results in increased susceptibility to Erlotinib Hydrochloride; Niclosamide inhibits the reaction [Erlotinib Hydrochloride results in increased expression of BCL2L2 protein]		 CTD PMID:23894143 NCBI chr15:28,346,449...28,361,627
Ensembl chr15:28,356,807...28,361,624 		JBrowse link
G Bcl3 BCL3, transcription coactivator increases expression ISO Niclosamide results in increased expression of BCL3 mRNA CTD PMID:36318118 NCBI chr 1:79,471,368...79,485,908
Ensembl chr 1:79,471,369...79,485,607 		JBrowse link
G Bcl6 BCL6, transcription repressor multiple interactions
increases expression		 ISO Niclosamide affects the reaction [FAS protein mutant form affects the expression of BCL6 mRNA]; Niclosamide affects the reaction [FAS protein mutant form affects the expression of BCL6 protein]
Niclosamide results in increased expression of BCL6 mRNA		 CTD PMID:33632240 PMID:36318118 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389 		JBrowse link
G Bcl6b BCL6B, transcription repressor increases expression ISO Niclosamide results in increased expression of BCL6B mRNA CTD PMID:36318118 NCBI chr10:54,940,908...54,947,022
Ensembl chr10:54,940,909...54,945,974 		JBrowse link
G Bcl9 BCL9, transcription coactivator decreases expression EXP Niclosamide results in decreased expression of BCL9 mRNA CTD PMID:27338550 NCBI chr 2:184,760,616...184,846,261
Ensembl chr 2:184,760,618...184,786,435 		JBrowse link
G Bcorl1 BCL6 co-repressor-like 1 increases expression ISO Niclosamide results in increased expression of BCORL1 mRNA CTD PMID:36318118 NCBI chr  X:127,516,504...127,584,529
Ensembl chr  X:127,537,538...127,584,087 		JBrowse link
G Bet1l Bet1 golgi vesicular membrane trafficking protein-like increases expression ISO Niclosamide results in increased expression of BET1L mRNA CTD PMID:36318118 NCBI chr 1:195,931,407...195,935,072
Ensembl chr 1:195,931,411...195,935,040 		JBrowse link
G Bgn biglycan increases expression ISO Niclosamide results in increased expression of BGN mRNA CTD PMID:36318118 NCBI chr  X:151,197,296...151,209,458
Ensembl chr  X:151,197,273...151,209,461 		JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 increases expression ISO Niclosamide results in increased expression of BHLHE40 mRNA CTD PMID:36318118 NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions
decreases expression
affects expression		 ISO enzalutamide promotes the reaction [Niclosamide results in decreased expression of BIRC5 protein]; Niclosamide inhibits the reaction [IL6 protein results in increased expression of BIRC5 protein]
Niclosamide analog results in decreased expression of BIRC5 protein; Niclosamide results in decreased expression of BIRC5 mRNA; Niclosamide results in decreased expression of BIRC5 protein
Niclosamide affects the expression of BIRC5 protein		 CTD PMID:24552774 PMID:24736023 PMID:25970160 PMID:28284560 PMID:28500234 More... NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Bmf Bcl2 modifying factor increases expression ISO Niclosamide results in increased expression of BMF mRNA CTD PMID:36318118 NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145 		JBrowse link
G Borcs6 BLOC-1 related complex subunit 6 increases expression ISO Niclosamide results in increased expression of BORCS6 mRNA CTD PMID:36318118 NCBI chr10:53,760,504...53,762,358
Ensembl chr10:53,758,093...53,762,632 		JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase decreases expression
decreases phosphorylation		 ISO Niclosamide analog results in decreased expression of BRAF protein; Niclosamide results in decreased expression of BRAF protein
Niclosamide analog results in decreased phosphorylation of BRAF protein		 CTD PMID:28284560 NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463 		JBrowse link
G Btbd7 BTB domain containing 7 decreases expression ISO Niclosamide results in decreased expression of BTBD7 mRNA CTD PMID:36318118 NCBI chr 6:121,920,365...122,010,114
Ensembl chr 6:121,923,023...121,972,405 		JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO Niclosamide results in increased expression of BTG2 mRNA CTD PMID:36318118 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628 		JBrowse link
G C13h1orf105 similar to human chromosome 1 open reading frame 105 decreases expression ISO Niclosamide results in decreased expression of C1ORF105 mRNA CTD PMID:36318118 NCBI chr13:74,313,320...74,356,322
Ensembl chr13:74,313,322...74,356,322 		JBrowse link
G C16h8orf48 similar to human chromosome 8 open reading frame 48 decreases expression ISO Niclosamide results in decreased expression of C8ORF48 mRNA CTD PMID:36318118 NCBI chr16:55,244,744...55,246,642
Ensembl chr16:55,236,322...55,246,650 		JBrowse link
G C19h16orf86 similar to human chromosome 16 open reading frame 86 increases expression ISO Niclosamide results in increased expression of C16ORF86 mRNA CTD PMID:36318118 NCBI chr19:33,596,591...33,598,703
Ensembl chr19:33,595,995...33,598,521 		JBrowse link
G C1ql4 complement C1q like 4 increases expression ISO Niclosamide results in increased expression of C1QL4 mRNA CTD PMID:36318118 NCBI chr 7:130,243,606...130,246,678
Ensembl chr 7:130,243,606...130,246,678 		JBrowse link
G Cables2 Cdk5 and Abl enzyme substrate 2 decreases expression ISO Niclosamide results in decreased expression of CABLES2 mRNA CTD PMID:36318118 NCBI chr 3:167,347,527...167,362,274
Ensembl chr 3:167,347,461...167,362,279 		JBrowse link
G Cacna1e calcium voltage-gated channel subunit alpha1 E increases expression ISO Niclosamide results in increased expression of CACNA1E mRNA CTD PMID:36318118 NCBI chr13:66,574,659...67,063,443
Ensembl chr13:66,581,920...66,894,450 		JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H increases expression ISO Niclosamide results in increased expression of CACNA1H mRNA CTD PMID:36318118 NCBI chr10:14,390,104...14,448,204
Ensembl chr10:14,390,113...14,448,376 		JBrowse link
G Cacng1 calcium voltage-gated channel auxiliary subunit gamma 1 increases expression ISO Niclosamide results in increased expression of CACNG1 mRNA CTD PMID:36318118 NCBI chr10:92,652,924...92,665,612
Ensembl chr10:92,652,614...92,665,783 		JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha increases expression ISO Niclosamide results in increased expression of CAMK2A mRNA CTD PMID:36318118 NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994 		JBrowse link
G Camsap3 calmodulin regulated spectrin-associated protein family, member 3 increases expression ISO Niclosamide results in increased expression of CAMSAP3 mRNA CTD PMID:36318118 NCBI chr12:1,643,062...1,666,685
Ensembl chr12:1,643,251...1,666,685 		JBrowse link
G Caps calcyphosine increases expression ISO Niclosamide results in increased expression of CAPS mRNA CTD PMID:36318118 NCBI chr 9:1,544,597...1,545,631
Ensembl chr 9:1,544,719...1,545,647 		JBrowse link
G Casp1 caspase 1 multiple interactions ISO [Niclosamide co-treated with Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of CASP1 protein
Niclosamide inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased cleavage of CASP1 protein]		 CTD PMID:33524445 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions
decreases expression
increases expression		 ISO
EXP		 Niclosamide results in increased cleavage of CASP3 protein
7-methyl-5-(1-((3-(trifluoromethyl)phenyl)acetyl)-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo(2,3-d)pyrimidin-4-amine inhibits the reaction [Niclosamide results in increased cleavage of CASP3 protein]; [Niclosamide binds to Polyethyleneimine] which results in increased expression of CASP3 mRNA; ATF3 protein affects the reaction [Niclosamide results in increased cleavage of CASP3 protein]; benzyloxycarbonyl-valyl-alanyl-aspartic acid inhibits the reaction [Niclosamide results in increased cleavage of CASP3 protein]; TP53 gene mutant form promotes the reaction [Niclosamide results in increased cleavage of CASP3 protein]; WNT7A protein affects the reaction [Niclosamide results in increased cleavage of CASP3 protein]
Niclosamide results in decreased expression of CASP3 protein
Niclosamide results in increased expression of CASP3 protein modified form
[TP53 protein mutant form results in increased susceptibility to Niclosamide] which results in increased expression of CASP3 protein modified form; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of CASP3 protein modified form]
Niclosamide inhibits the reaction [Thioacetamide results in decreased expression of CASP3 mRNA]; Poloxamer promotes the reaction [Niclosamide inhibits the reaction [Thioacetamide results in decreased expression of CASP3 mRNA]]		 CTD PMID:20215516 PMID:21871175 PMID:24750999 PMID:25174399 PMID:25634333 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp7 caspase 7 multiple interactions
increases expression		 ISO bicalutamide promotes the reaction [Niclosamide results in increased expression of CASP7 protein modified form] CTD PMID:26116531 PMID:28500234 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729 		JBrowse link
G Casp8 caspase 8 increases cleavage ISO Niclosamide results in increased cleavage of CASP8 protein CTD PMID:35115509 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 multiple interactions
increases cleavage
increases expression		 ISO TP53 gene mutant form promotes the reaction [Niclosamide results in increased cleavage of CASP9 protein]
Niclosamide results in increased expression of CASP9 mRNA; Niclosamide results in increased expression of CASP9 protein modified form		 CTD PMID:26116531 PMID:26703449 PMID:30258081 PMID:36318118 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cbx4 chromobox 4 increases expression ISO Niclosamide results in increased expression of CBX4 mRNA CTD PMID:36318118 NCBI chr10:104,337,140...104,343,210
Ensembl chr10:104,336,876...104,356,706 		JBrowse link
G Ccdc113 coiled-coil domain containing 113 increases expression ISO Niclosamide results in increased expression of CFAP263 mRNA CTD PMID:36318118 NCBI chr19:9,497,000...9,516,917
Ensembl chr19:9,496,886...9,516,923 		JBrowse link
G Ccdc188 coiled-coil domain containing 188 increases expression ISO Niclosamide results in increased expression of CCDC188 mRNA CTD PMID:36318118 NCBI chr11:82,769,735...82,772,062
Ensembl chr11:82,769,473...82,772,114 		JBrowse link
G Ccdc68 coiled-coil domain containing 68 decreases expression ISO Niclosamide results in decreased expression of CCDC68 mRNA CTD PMID:36318118 NCBI chr18:63,541,828...63,584,122
Ensembl chr18:63,541,896...63,584,119 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO
EXP		 Niclosamide inhibits the reaction [Doxorubicin results in increased expression of CCL2 mRNA]; Niclosamide inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL2 protein]
Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of CCL2 mRNA]		 CTD PMID:24561310 PMID:28318631 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 multiple interactions ISO
EXP		 Niclosamide inhibits the reaction [Doxorubicin results in increased expression of CCL20 mRNA]
Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of CCL20 mRNA]		 CTD PMID:28318631 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO Niclosamide inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL3 protein] CTD PMID:24561310 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO Niclosamide inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL5 protein] CTD PMID:24561310 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO Niclosamide results in decreased expression of CCNB1 mRNA CTD PMID:28284560 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Ccnb3 cyclin B3 decreases expression ISO Niclosamide results in decreased expression of CCNB3 mRNA CTD PMID:36318118 NCBI chr  X:15,478,050...15,543,292
Ensembl chr  X:15,478,065...15,542,885 		JBrowse link
G Ccnd1 cyclin D1 multiple interactions
decreases expression		 EXP
ISO		 Niclosamide inhibits the reaction [Epinephrine results in increased expression of CCND1 mRNA]; Niclosamide inhibits the reaction [GCG protein results in increased expression of CCND1 mRNA]; Niclosamide inhibits the reaction [GCG protein results in increased expression of CCND1 protein]; Niclosamide inhibits the reaction [Thioacetamide results in increased expression of CCND1 mRNA]; Niclosamide inhibits the reaction [Thioacetamide results in increased expression of CCND1 protein]; Poloxamer promotes the reaction [Niclosamide inhibits the reaction [Thioacetamide results in increased expression of CCND1 mRNA]]; Poloxamer promotes the reaction [Niclosamide inhibits the reaction [Thioacetamide results in increased expression of CCND1 protein]]
Niclosamide inhibits the reaction [IL6 protein results in increased expression of CCND1 mRNA]; Niclosamide inhibits the reaction [TNF protein results in increased expression of CCND1 mRNA]; Niclosamide promotes the reaction [bicalutamide results in decreased expression of CCND1 protein]
Niclosamide analog results in decreased expression of CCND1 protein; Niclosamide results in decreased expression of CCND1 mRNA; Niclosamide results in decreased expression of CCND1 protein		 CTD PMID:19160421 PMID:20215516 PMID:24552774 PMID:24736023 PMID:26297436 More... NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccnd2 cyclin D2 decreases expression
increases expression		 ISO Niclosamide results in decreased expression of CCND2 mRNA
Niclosamide results in increased expression of CCND2 mRNA		 CTD PMID:22576131 PMID:27226553 PMID:36318118 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495 		JBrowse link
G Ccnd3 cyclin D3 decreases expression ISO Niclosamide results in decreased expression of CCND3 mRNA CTD PMID:22576131 PMID:27226553 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371 		JBrowse link
G Ccne1 cyclin E1 decreases expression ISO Niclosamide results in decreased expression of CCNE1 mRNA CTD PMID:36318118 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101 		JBrowse link
G Ccne2 cyclin E2 multiple interactions
decreases expression		 ISO Niclosamide inhibits the reaction [PIK3CA protein modified form results in increased expression of CCNE2 mRNA]
Niclosamide results in decreased expression of CCNE2 mRNA		 CTD PMID:27542212 PMID:36318118 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632 		JBrowse link
G Ccng2 cyclin G2 multiple interactions
increases expression		 ISO Niclosamide inhibits the reaction [PIK3CA protein modified form results in decreased expression of CCNG2 mRNA]
Niclosamide results in increased expression of CCNG2 mRNA		 CTD PMID:27542212 PMID:36318118 NCBI chr14:14,804,321...14,812,819
Ensembl chr14:14,804,322...14,812,830 		JBrowse link
G Ccr10 C-C motif chemokine receptor 10 increases expression ISO Niclosamide results in increased expression of CCR10 mRNA CTD PMID:36318118 NCBI chr10:86,108,551...86,110,988
Ensembl chr10:86,108,551...86,110,988 		JBrowse link
G Cd27 CD27 molecule increases expression ISO Niclosamide results in increased expression of CD27 mRNA CTD PMID:36318118 NCBI chr 4:158,030,700...158,035,862
Ensembl chr 4:158,030,703...158,035,592 		JBrowse link
G Cd274 CD274 molecule decreases expression ISO Niclosamide results in decreased expression of CD274 mRNA; Niclosamide results in decreased expression of CD274 protein CTD PMID:35115509 NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450 		JBrowse link
G Cd40 CD40 molecule multiple interactions ISO Niclosamide inhibits the reaction [Lipopolysaccharides affects the expression of CD40 protein] CTD PMID:24561310 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534 		JBrowse link
G Cd55 CD55 molecule (Cromer blood group) increases expression ISO Niclosamide results in increased expression of CD55 mRNA CTD PMID:36318118 NCBI chr13:41,857,242...41,885,966
Ensembl chr13:41,857,395...41,885,831 		JBrowse link
G Cd68 Cd68 molecule increases expression ISO Niclosamide results in increased expression of CD68 mRNA CTD PMID:36318118 NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697 		JBrowse link
G Cd80 Cd80 molecule multiple interactions ISO Niclosamide inhibits the reaction [Lipopolysaccharides affects the expression of CD80 protein] CTD PMID:24561310 NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030 		JBrowse link
G Cd86 CD86 molecule multiple interactions ISO Niclosamide inhibits the reaction [Lipopolysaccharides affects the expression of CD86 protein] CTD PMID:24561310 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818 		JBrowse link
G Cdc37 cell division cycle 37, HSP90 cochaperone multiple interactions ISO CDC37 protein binds to and results in increased susceptibility to Niclosamide analog CTD PMID:28284560 NCBI chr 8:19,677,400...19,690,761
Ensembl chr 8:19,671,938...19,690,809 		JBrowse link
G Cdc42 cell division cycle 42 decreases expression
decreases phosphorylation		 ISO Niclosamide results in decreased expression of CDC42 mRNA
Niclosamide results in decreased phosphorylation of CDC42 protein		 CTD PMID:29251334 NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111 		JBrowse link
G Cdc42ep1 CDC42 effector protein 1 increases expression ISO Niclosamide results in increased expression of CDC42EP1 mRNA CTD PMID:36318118 NCBI chr 7:110,395,287...110,403,203
Ensembl chr 7:110,395,332...110,403,200 		JBrowse link
G Cdc6 cell division cycle 6 decreases expression ISO Niclosamide results in decreased expression of CDC6 mRNA CTD PMID:28284560 PMID:36318118 NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011 		JBrowse link
G Cdca2 cell division cycle associated 2 decreases expression ISO Niclosamide results in decreased expression of CDCA2 mRNA CTD PMID:28284560 NCBI chr15:41,895,946...41,942,226
Ensembl chr15:41,895,901...41,941,611 		JBrowse link
G Cdca5 cell division cycle associated 5 decreases expression ISO Niclosamide results in decreased expression of CDCA5 mRNA CTD PMID:28284560 NCBI chr 1:203,378,550...203,392,027
Ensembl chr 1:203,378,577...203,392,023 		JBrowse link
G Cdca8 cell division cycle associated 8 decreases expression ISO Niclosamide results in decreased expression of CDCA8 mRNA CTD PMID:28284560 NCBI chr 5:137,176,414...137,198,686
Ensembl chr 5:137,176,417...137,198,629 		JBrowse link
G Cdh1 cadherin 1 multiple interactions
increases expression		 ISO CTNNB1 protein inhibits the reaction [Niclosamide results in increased expression of CDH1 protein]; Niclosamide inhibits the reaction [[Lapatinib results in decreased susceptibility to Lapatinib] which results in decreased expression of CDH1 protein]; WNT7A protein affects the reaction [Niclosamide results in increased expression of CDH1 protein]
Niclosamide results in increased expression of CDH1 mRNA; Niclosamide results in increased expression of CDH1 protein		 CTD PMID:25174399 PMID:26643609 PMID:30143678 PMID:35115509 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Cdh11 cadherin 11 decreases expression ISO Niclosamide results in decreased expression of CDH11 mRNA CTD PMID:36318118 NCBI chr19:2,148,447...2,305,754
Ensembl chr19:2,148,458...2,304,272 		JBrowse link
G Cdh12 cadherin 12 multiple interactions ISO Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of CDH12 protein] CTD PMID:36870549 NCBI chr 2:70,474,679...71,705,369
Ensembl chr 2:70,475,043...71,700,572 		JBrowse link
G Cdh2 cadherin 2 multiple interactions ISO Niclosamide inhibits the reaction [[Lapatinib results in decreased susceptibility to Lapatinib] which results in increased expression of CDH2 protein] CTD PMID:26643609 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167 		JBrowse link
G Cdh4 cadherin 4 increases expression ISO Niclosamide results in increased expression of CDH4 mRNA CTD PMID:36318118 NCBI chr 3:166,525,092...167,003,380
Ensembl chr 3:166,525,099...167,003,371 		JBrowse link
G Cdh6 cadherin 6 decreases expression ISO Niclosamide results in decreased expression of CDH6 mRNA CTD PMID:36318118 NCBI chr 2:62,079,139...62,225,298
Ensembl chr 2:62,079,137...62,225,228 		JBrowse link
G Cdhr1 cadherin-related family member 1 increases expression ISO Niclosamide results in increased expression of CDHR1 mRNA CTD PMID:36318118 NCBI chr16:12,843,436...12,863,321
Ensembl chr16:12,843,437...12,863,396 		JBrowse link
G Cdhr2 cadherin-related family member 2 decreases expression ISO Niclosamide results in decreased expression of CDHR2 mRNA CTD PMID:36318118 NCBI chr17:9,876,853...9,913,356
Ensembl chr17:9,876,860...9,912,575 		JBrowse link
G Cdk15 cyclin-dependent kinase 15 decreases expression ISO Niclosamide results in decreased expression of CDK15 mRNA CTD PMID:36318118 NCBI chr 9:60,710,787...60,803,638
Ensembl chr 9:60,711,715...60,802,777 		JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression ISO Niclosamide results in decreased expression of CDK2 protein CTD PMID:29031202 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression ISO Niclosamide results in decreased expression of CDK4 protein CTD PMID:29031202 NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403 		JBrowse link
G Cdkl3 cyclin-dependent kinase-like 3 increases expression ISO Niclosamide results in increased expression of CDKL3 mRNA CTD PMID:36318118 NCBI chr10:36,263,212...36,349,268
Ensembl chr10:36,266,977...36,349,268 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression		 ISO TP53 gene mutant form inhibits the reaction [Niclosamide results in increased expression of CDKN1A mRNA]; TP53 protein mutant form inhibits the reaction [Niclosamide results in increased expression of CDKN1A mRNA] CTD PMID:30258081 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 decreases expression ISO Niclosamide results in decreased expression of CDKN3 mRNA CTD PMID:28284560 NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression ISO Niclosamide results in increased expression of CEBPB mRNA CTD PMID:36318118 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473 		JBrowse link
G Celf6 CUGBP, Elav-like family member 6 increases expression ISO Niclosamide results in increased expression of CELF6 mRNA CTD PMID:36318118 NCBI chr 8:59,975,095...60,006,060
Ensembl chr 8:59,975,088...60,005,041 		JBrowse link
G Celsr3 cadherin, EGF LAG seven-pass G-type receptor 3 increases expression ISO Niclosamide results in increased expression of CELSR3 mRNA CTD PMID:28284560 NCBI chr 8:109,530,597...109,558,360
Ensembl chr 8:109,530,641...109,558,354 		JBrowse link
G Cenpa centromere protein A decreases expression ISO Niclosamide results in decreased expression of CENPA mRNA CTD PMID:28284560 NCBI chr 6:25,700,142...25,711,767
Ensembl chr 6:25,700,142...25,711,675 		JBrowse link
G Cenpo centromere protein O decreases expression ISO Niclosamide results in decreased expression of CENPO mRNA CTD PMID:36318118 NCBI chr 6:27,203,642...27,218,394
Ensembl chr 6:27,188,537...27,218,314 		JBrowse link
G Cenpu centromere protein U decreases expression ISO Niclosamide results in decreased expression of CENPU mRNA CTD PMID:36318118 NCBI chr16:45,715,821...45,739,038
Ensembl chr16:45,714,294...45,738,823 		JBrowse link
G Cfap70 cilia and flagella associated protein 70 increases expression ISO Niclosamide results in increased expression of CFAP70 mRNA CTD PMID:36318118 NCBI chr15:3,852,381...3,918,036
Ensembl chr15:3,852,509...3,918,014 		JBrowse link
G Cfp complement factor properdin increases expression ISO Niclosamide results in increased expression of CFP mRNA CTD PMID:28284560 NCBI chr  X:1,162,014...1,167,576
Ensembl chr  X:1,161,979...1,167,573 		JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 increases expression ISO Niclosamide results in increased expression of CHAC1 mRNA CTD PMID:36318118 NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526 		JBrowse link
G Chac2 ChaC glutathione specific gamma-glutamylcyclotransferase 2 decreases expression ISO Niclosamide results in decreased expression of CHAC2 mRNA CTD PMID:36318118 NCBI chr14:104,720,754...104,728,305
Ensembl chr14:104,720,758...104,728,301 		JBrowse link
G Chaf1a chromatin assembly factor 1 subunit A decreases expression ISO Niclosamide results in decreased expression of CHAF1A mRNA CTD PMID:36318118 NCBI chr 9:873,953...900,701
Ensembl chr 9:874,051...900,654 		JBrowse link
G Chrnb1 cholinergic receptor nicotinic beta 1 subunit increases expression ISO Niclosamide results in increased expression of CHRNB1 mRNA CTD PMID:36318118 NCBI chr10:54,501,096...54,516,418
Ensembl chr10:54,501,093...54,516,345 		JBrowse link
G Chst8 carbohydrate sulfotransferase 8 increases expression ISO Niclosamide results in increased expression of CHST8 mRNA CTD PMID:36318118 NCBI chr 1:87,294,144...87,435,900
Ensembl chr 1:87,294,540...87,435,900 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions ISO Niclosamide results in decreased phosphorylation of and affects the localization of CHUK protein CTD PMID:26116531 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065 		JBrowse link
G Cish cytokine inducible SH2-containing protein increases expression ISO Niclosamide results in increased expression of CISH mRNA CTD PMID:36318118 NCBI chr 8:107,972,306...107,977,254
Ensembl chr 8:107,972,306...107,977,250 		JBrowse link
G Clec11a C-type lectin domain containing 11A increases expression ISO Niclosamide results in increased expression of CLEC11A mRNA CTD PMID:36318118 NCBI chr 1:94,800,456...94,809,002
Ensembl chr 1:94,801,496...94,804,633 		JBrowse link
G Clip2 CAP-GLY domain containing linker protein 2 increases expression ISO Niclosamide results in increased expression of CLIP2 mRNA CTD PMID:36318118 NCBI chr12:22,163,044...22,227,023
Ensembl chr12:22,163,218...22,227,023 		JBrowse link
G Clip3 CAP-GLY domain containing linker protein 3 increases expression ISO Niclosamide results in increased expression of CLIP3 mRNA CTD PMID:36318118 NCBI chr 1:85,547,170...85,563,187
Ensembl chr 1:85,547,206...85,563,184 		JBrowse link
G Clspn claspin decreases expression ISO Niclosamide results in decreased expression of CLSPN mRNA CTD PMID:36318118 NCBI chr 5:138,850,119...138,885,037
Ensembl chr 5:138,850,128...138,885,034 		JBrowse link
G Clstn3 calsyntenin 3 increases expression ISO Niclosamide results in increased expression of CLSTN3 mRNA CTD PMID:36318118 NCBI chr 4:157,331,494...157,364,769
Ensembl chr 4:157,331,494...157,364,769 		JBrowse link
G Cmklr1 chemerin chemokine-like receptor 1 decreases expression ISO Niclosamide results in decreased expression of CMKLR1 mRNA CTD PMID:36318118 NCBI chr12:42,974,462...43,027,321
Ensembl chr12:42,974,410...43,028,129 		JBrowse link
G Cmpk2 cytidine/uridine monophosphate kinase 2 decreases expression ISO Niclosamide results in decreased expression of CMPK2 mRNA CTD PMID:36318118 NCBI chr 6:43,073,706...43,085,183
Ensembl chr 6:43,073,796...43,085,183 		JBrowse link
G Cnbd2 cyclic nucleotide binding domain containing 2 increases expression ISO Niclosamide results in increased expression of CNBD2 mRNA CTD PMID:36318118 NCBI chr 3:144,819,166...144,884,825
Ensembl chr 3:144,819,195...144,901,583 		JBrowse link
G Cnn1 calponin 1 increases expression ISO Niclosamide results in increased expression of CNN1 mRNA CTD PMID:36318118 NCBI chr 8:20,632,434...20,641,097
Ensembl chr 8:20,632,338...20,641,098 		JBrowse link
G Cnn2 calponin 2 increases expression ISO Niclosamide results in increased expression of CNN2 mRNA CTD PMID:36318118 NCBI chr 7:9,712,505...9,719,678
Ensembl chr 7:9,712,516...9,719,656 		JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression
multiple interactions		 ISO Niclosamide results in decreased expression of COL1A1 mRNA
Niclosamide results in decreased expression of COL1A1 protein
CTNNB1 protein inhibits the reaction [Niclosamide results in decreased expression of COL1A1 protein]; Gemcitabine inhibits the reaction [Niclosamide results in decreased expression of COL1A1 protein]; Niclosamide inhibits the reaction [Gemcitabine results in decreased expression of COL1A1 protein]		 CTD PMID:28824321 PMID:35115509 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Col6a2 collagen type VI alpha 2 chain increases expression ISO Niclosamide results in increased expression of COL6A2 mRNA CTD PMID:36318118 NCBI chr20:12,021,676...12,049,425
Ensembl chr20:12,021,767...12,057,564 		JBrowse link
G Colec10 collectin subfamily member 10 increases expression ISO Niclosamide results in increased expression of COLEC10 mRNA CTD PMID:28284560 NCBI chr 7:85,744,895...85,806,368
Ensembl chr 7:85,744,895...85,805,675 		JBrowse link
G Cox8c cytochrome c oxidase subunit 8C increases expression ISO Niclosamide results in increased expression of COX8C mRNA CTD PMID:36318118 NCBI chr 6:122,028,566...122,029,889
Ensembl chr 6:122,028,566...122,029,889 		JBrowse link
G Crb2 crumbs cell polarity complex component 2 increases expression ISO Niclosamide results in increased expression of CRB2 mRNA CTD PMID:36318118 NCBI chr 3:21,542,138...21,564,876
Ensembl chr 3:21,542,221...21,563,294 		JBrowse link
G Crebbp CREB binding protein increases expression ISO Niclosamide results in increased expression of CREBBP mRNA CTD PMID:22576131 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888 		JBrowse link
G Crebrf CREB3 regulatory factor increases expression ISO Niclosamide results in increased expression of CREBRF mRNA CTD PMID:36318118 NCBI chr10:16,399,170...16,479,650
Ensembl chr10:16,404,596...16,461,999 		JBrowse link
G Crlf1 cytokine receptor-like factor 1 decreases expression ISO Niclosamide results in decreased expression of CRLF1 mRNA CTD PMID:36318118 NCBI chr16:18,924,722...18,936,049
Ensembl chr16:18,924,722...18,935,997 		JBrowse link
G Crot carnitine O-octanoyltransferase decreases expression ISO Niclosamide results in decreased expression of CROT mRNA CTD PMID:36318118 NCBI chr 4:25,068,270...25,133,111
Ensembl chr 4:25,080,587...25,133,109 		JBrowse link
G Crybb1 crystallin, beta B1 increases expression ISO Niclosamide results in increased expression of CRYBB1 mRNA CTD PMID:36318118 NCBI chr12:44,369,734...44,383,344
Ensembl chr12:44,369,735...44,383,344 		JBrowse link
G Cryl1 crystallin, lambda 1 increases expression ISO Niclosamide results in increased expression of CRYL1 mRNA CTD PMID:36318118 NCBI chr15:31,427,011...31,545,997
Ensembl chr15:31,427,054...31,545,997 		JBrowse link
G Csf1 colony stimulating factor 1 multiple interactions ISO Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of ACP5 mRNA]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of and affects the localization of NFATC1 protein]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of CASP3 protein modified form]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of FOS mRNA]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of ITGB3 mRNA]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of MMP9 mRNA]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of NFATC1 mRNA]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of OCSTAMP mRNA]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of OSCAR mRNA]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of TRAF6 protein]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of MAPK1 protein]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of MAPK3 protein]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of MAPK8 protein]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of MAPK9 protein]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of NFKBIA protein]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of RELA protein] CTD PMID:28824321 NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704 		JBrowse link
G Csgalnact1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 multiple interactions ISO Niclosamide inhibits the reaction [PIK3CA protein modified form results in decreased expression of CSGALNACT1 mRNA] CTD PMID:27542212 NCBI chr16:20,995,210...21,330,586
Ensembl chr16:21,235,784...21,330,319 		JBrowse link
G Csnk1e casein kinase 1, epsilon increases expression ISO Niclosamide results in increased expression of CSNK1E mRNA CTD PMID:22576131 NCBI chr 7:110,983,322...111,006,926
Ensembl chr 7:110,983,318...111,006,794 		JBrowse link
G Csrnp1 cysteine and serine rich nuclear protein 1 increases expression ISO Niclosamide results in increased expression of CSRNP1 mRNA CTD PMID:28284560 NCBI chr 8:119,704,712...119,717,767
Ensembl chr 8:119,704,713...119,718,183 		JBrowse link
G Ctbp1 C-terminal binding protein 1 increases expression ISO Niclosamide results in increased expression of CTBP1 mRNA CTD PMID:22576131 NCBI chr14:77,455,580...77,482,821
Ensembl chr14:77,455,696...77,482,821 		JBrowse link
G Ctnnb1 catenin beta 1 increases expression
multiple interactions
decreases expression
decreases activity
increases ubiquitination
affects localization		 ISO
EXP		 Niclosamide results in increased expression of CTNNB1 mRNA
CTNNB1 protein inhibits the reaction [Niclosamide results in decreased expression of ACTA2 protein]; CTNNB1 protein inhibits the reaction [Niclosamide results in decreased expression of COL1A1 protein]; CTNNB1 protein inhibits the reaction [Niclosamide results in increased expression of CDH1 protein]; Imatinib Mesylate promotes the reaction [Niclosamide results in decreased expression of CTNNB1 protein]; Niclosamide inhibits the reaction [CTNNB1 protein binds to CTNNBIP1 protein]; Niclosamide inhibits the reaction [Lithium Chloride affects the localization of CTNNB1 protein]; Niclosamide inhibits the reaction [TNF protein affects the localization of CTNNB1 protein]; Niclosamide inhibits the reaction [WNT3A protein affects the localization of CTNNB1 protein]; Niclosamide inhibits the reaction [WNT3A protein results in increased stability of CTNNB1 protein]; Niclosamide promotes the reaction [Imatinib Mesylate results in decreased expression of CTNNB1 protein]; Niclosamide results in decreased expression of and results in increased phosphorylation of CTNNB1 protein
Niclosamide analog results in decreased expression of CTNNB1 protein; Niclosamide results in decreased expression of CTNNB1 protein
Niclosamide inhibits the reaction [Epinephrine results in increased phosphorylation of CTNNB1 protein]; Niclosamide inhibits the reaction [GCG protein results in increased phosphorylation of CTNNB1 protein]; Niclosamide inhibits the reaction [Thioacetamide results in increased expression of CTNNB1 protein]; Poloxamer promotes the reaction [Niclosamide inhibits the reaction [Thioacetamide results in increased expression of CTNNB1 protein]]
Niclosamide results in decreased activity of CTNNB1 protein
Niclosamide results in increased ubiquitination of CTNNB1 protein
Niclosamide results in decreased expression of CTNNB1 mRNA
Niclosamide affects the localization of CTNNB1 protein		 CTD PMID:19772353 PMID:21531761 PMID:22576131 PMID:24534281 PMID:24552774 More... NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Ctnnbip1 catenin, beta-interacting protein 1 multiple interactions
increases expression		 ISO Niclosamide inhibits the reaction [CTNNB1 protein binds to CTNNBIP1 protein]
Niclosamide results in increased expression of CTNNBIP1 mRNA		 CTD PMID:24534281 PMID:36318118 NCBI chr 5:159,961,961...160,010,942
Ensembl chr 5:159,961,928...160,010,939 		JBrowse link
G Ctsc cathepsin C decreases expression ISO Niclosamide results in decreased expression of CTSC protein CTD PMID:29480568 NCBI chr 1:142,028,386...142,059,841
Ensembl chr 1:142,028,392...142,060,387 		JBrowse link
G Ctsd cathepsin D decreases expression ISO Niclosamide results in decreased expression of CTSD protein CTD PMID:29480568 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488 		JBrowse link
G Ctsk cathepsin K multiple interactions ISO Niclosamide inhibits the reaction [TNFSF11 protein results in increased expression of CTSK mRNA] CTD PMID:26792726 NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases expression ISO Niclosamide results in decreased expression of CXCL12 mRNA CTD PMID:36318118 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Cxcr5 C-X-C motif chemokine receptor 5 multiple interactions ISO Niclosamide affects the reaction [FAS protein mutant form affects the expression of CXCR5 mRNA] CTD PMID:33632240 NCBI chr 8:44,842,098...44,858,425
Ensembl chr 8:44,843,413...44,857,893 		JBrowse link
G Cyb561 cytochrome b-561 decreases expression ISO Niclosamide results in decreased expression of CYB561 mRNA CTD PMID:36318118 NCBI chr10:90,878,052...90,888,734
Ensembl chr10:90,878,054...90,884,787 		JBrowse link
G Cycs cytochrome c, somatic increases expression ISO Niclosamide results in increased expression of CYCS protein CTD PMID:26703449 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases activity ISO Niclosamide results in increased activity of CYP1A1 protein CTD PMID:12451431 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity
increases expression		 ISO Niclosamide results in decreased activity of CYP1A2 protein
Niclosamide results in increased expression of CYP1A2 mRNA		 CTD PMID:11124226 PMID:28284560 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 increases expression ISO Niclosamide results in increased expression of CYP27A1 mRNA CTD PMID:36318118 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases activity ISO Niclosamide results in decreased activity of CYP2D6 protein CTD PMID:11124226 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Cyp39a1 cytochrome P450, family 39, subfamily a, polypeptide 1 increases expression ISO Niclosamide results in increased expression of CYP39A1 mRNA CTD PMID:28284560 NCBI chr 9:17,230,455...17,306,775
Ensembl chr 9:17,230,455...17,306,775 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases activity ISO Niclosamide results in decreased activity of CYP3A4 protein CTD PMID:11124226 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Dact3 dishevelled-binding antagonist of beta-catenin 3 increases expression ISO Niclosamide results in increased expression of DACT3 mRNA CTD PMID:36318118 NCBI chr 1:77,546,900...77,558,631
Ensembl chr 1:77,546,900...77,558,630 		JBrowse link
G Dbp D-box binding PAR bZIP transcription factor increases expression ISO Niclosamide results in increased expression of DBP mRNA CTD PMID:36318118 NCBI chr 1:96,175,796...96,180,745
Ensembl chr 1:96,175,440...96,180,745 		JBrowse link
G Ddah2 DDAH family member 2, ADMA-independent increases expression ISO Niclosamide results in increased expression of DDAH2 mRNA CTD PMID:36318118 NCBI chr20:3,761,460...3,764,718
Ensembl chr20:3,761,465...3,764,511 		JBrowse link
G Ddias DNA damage-induced apoptosis suppressor decreases expression ISO Niclosamide results in decreased expression of DDIAS mRNA CTD PMID:36318118 NCBI chr 1:146,906,150...146,930,462
Ensembl chr 1:146,906,154...146,930,462 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions		 ISO Niclosamide results in increased expression of DDIT3 mRNA; Niclosamide results in increased expression of DDIT3 protein
ATF3 protein affects the reaction [Niclosamide results in increased expression of DDIT3 mRNA]		 CTD PMID:26917416 PMID:36318118 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression ISO Niclosamide results in increased expression of DDIT4 mRNA CTD PMID:36318118 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105 		JBrowse link
G Ddr1 discoidin domain receptor tyrosine kinase 1 increases expression ISO Niclosamide results in increased expression of DDR1 mRNA CTD PMID:36318118 NCBI chr20:3,042,494...3,064,442
Ensembl chr20:3,044,320...3,064,468 		JBrowse link
G Decr1 2,4-dienoyl-CoA reductase 1 decreases expression ISO Niclosamide results in decreased expression of DECR1 mRNA CTD PMID:22576131 NCBI chr 5:29,411,172...29,439,054
Ensembl chr 5:29,411,172...29,439,018 		JBrowse link
G Dgcr8 DGCR8 microprocessor complex subunit decreases expression ISO Niclosamide results in decreased expression of DGCR8 mRNA CTD PMID:36318118 NCBI chr11:82,704,673...82,737,251
Ensembl chr11:82,704,729...82,737,242 		JBrowse link
G Dgkb diacylglycerol kinase, beta increases expression ISO Niclosamide results in increased expression of DGKB mRNA CTD PMID:36318118 NCBI chr 6:54,640,948...55,397,210
Ensembl chr 6:54,641,614...55,397,043 		JBrowse link
G Dhfr dihydrofolate reductase decreases expression ISO Niclosamide results in decreased expression of DHFR mRNA CTD PMID:36318118 NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713 		JBrowse link
G Dhrs3 dehydrogenase/reductase 3 increases expression ISO Niclosamide results in increased expression of DHRS3 mRNA CTD PMID:36318118 NCBI chr 5:156,747,939...156,782,420
Ensembl chr 5:156,747,962...156,782,417 		JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 decreases expression ISO Niclosamide results in decreased expression of DKK1 mRNA CTD PMID:36318118 NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202 		JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 increases expression ISO Niclosamide results in increased expression of DLG4 mRNA CTD PMID:36318118 NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153 		JBrowse link
G Dmac2l distal membrane arm assembly component 2 like decreases expression ISO Niclosamide results in decreased expression of DMAC2L mRNA CTD PMID:22576131 NCBI chr 6:88,205,580...88,223,934
Ensembl chr 6:88,205,700...88,223,933 		JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 decreases expression ISO Niclosamide results in decreased expression of DNAJA1 mRNA CTD PMID:36318118 NCBI chr 5:55,842,414...55,853,326
Ensembl chr 5:55,842,426...55,853,967 		JBrowse link
G Dnaja4 DnaJ heat shock protein family (Hsp40) member A4 decreases expression ISO Niclosamide results in decreased expression of DNAJA4 mRNA CTD PMID:36318118 NCBI chr 8:55,085,246...55,102,715
Ensembl chr 8:55,085,464...55,101,207 		JBrowse link
G Dnajc22 DnaJ heat shock protein family (Hsp40) member C22 increases expression ISO Niclosamide results in increased expression of DNAJC22 mRNA CTD PMID:36318118 NCBI chr 7:130,257,504...130,262,880
Ensembl chr 7:130,257,851...130,263,230 		JBrowse link
G Dnajc9 DnaJ heat shock protein family (Hsp40) member C9 decreases expression ISO Niclosamide results in decreased expression of DNAJC9 mRNA CTD PMID:36318118 NCBI chr15:3,923,842...3,928,118
Ensembl chr15:3,923,268...3,928,118 		JBrowse link
G Dock5 dedicator of cytokinesis 5 decreases expression ISO Niclosamide results in decreased expression of DOCK5 mRNA CTD PMID:36318118 NCBI chr15:41,979,728...42,158,733
Ensembl chr15:41,979,729...42,158,649 		JBrowse link
G Dqx1 DEAQ box RNA-dependent ATPase 1 increases expression ISO Niclosamide results in increased expression of DQX1 mRNA CTD PMID:36318118 NCBI chr 4:115,563,497...115,572,598
Ensembl chr 4:115,563,752...115,572,590 		JBrowse link
G Drd4 dopamine receptor D4 increases expression ISO Niclosamide results in increased expression of DRD4 mRNA CTD PMID:36318118 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553 		JBrowse link
G Dscc1 DNA replication and sister chromatid cohesion 1 multiple interactions ISO Niclosamide inhibits the reaction [PIK3CA protein modified form results in increased expression of DSCC1 mRNA] CTD PMID:27542212 NCBI chr 7:86,482,588...86,498,212
Ensembl chr 7:86,482,588...86,498,212 		JBrowse link
G Dtl denticleless E3 ubiquitin protein ligase homolog decreases expression ISO Niclosamide results in decreased expression of DTL mRNA CTD PMID:36318118 NCBI chr13:103,115,810...103,155,029
Ensembl chr13:103,117,186...103,154,890 		JBrowse link
G Dusp4 dual specificity phosphatase 4 increases expression ISO Niclosamide results in increased expression of DUSP4 mRNA CTD PMID:36318118 NCBI chr16:57,376,659...57,398,161
Ensembl chr16:57,377,229...57,398,138 		JBrowse link
G Dusp8 dual specificity phosphatase 8 increases expression ISO Niclosamide results in increased expression of DUSP8 mRNA CTD PMID:36318118 NCBI chr 1:197,167,392...197,184,285
Ensembl chr 1:197,169,422...197,182,921 		JBrowse link
G Dusp9 dual specificity phosphatase 9 increases expression ISO Niclosamide results in increased expression of DUSP9 mRNA CTD PMID:36318118 NCBI chr  X:151,351,897...151,355,822
Ensembl chr  X:151,351,897...151,355,821 		JBrowse link
G Dvl1 dishevelled segment polarity protein 1 increases expression ISO Niclosamide results in increased expression of DVL1 mRNA CTD PMID:22576131 NCBI chr 5:166,456,989...166,468,733
Ensembl chr 5:166,456,686...166,468,664 		JBrowse link
G Dvl2 dishevelled segment polarity protein 2 decreases expression
multiple interactions		 ISO
EXP		 Niclosamide results in decreased expression of DVL2 protein
Niclosamide inhibits the reaction [Thioacetamide results in increased expression of DVL2 mRNA]; Poloxamer promotes the reaction [Niclosamide inhibits the reaction [Thioacetamide results in increased expression of DVL2 mRNA]]		 CTD PMID:19772353 PMID:21531761 PMID:30143678 PMID:32961231 NCBI chr10:54,723,356...54,732,823
Ensembl chr10:54,723,411...54,732,820 		JBrowse link
G Dvl3 dishevelled segment polarity protein 3 increases expression ISO Niclosamide results in increased expression of DVL3 mRNA CTD PMID:22576131 NCBI chr11:80,365,446...80,382,641
Ensembl chr11:80,366,117...80,382,462 		JBrowse link
G Dyrk1b dual specificity tyrosine phosphorylation regulated kinase 1B increases expression ISO Niclosamide results in increased expression of DYRK1B mRNA CTD PMID:36318118 NCBI chr 1:83,479,168...83,497,011
Ensembl chr 1:83,479,147...83,487,169 		JBrowse link
G E2f1 E2F transcription factor 1 decreases expression ISO Niclosamide results in decreased expression of E2F1 mRNA CTD PMID:29843133 NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361 		JBrowse link
G E2f2 E2F transcription factor 2 decreases expression ISO Niclosamide results in decreased expression of E2F2 mRNA CTD PMID:36318118 NCBI chr 5:148,399,193...148,422,595
Ensembl chr 5:148,399,642...148,421,217 		JBrowse link
G E2f7 E2F transcription factor 7 decreases expression ISO Niclosamide results in decreased expression of E2F7 mRNA CTD PMID:36318118 NCBI chr 7:46,150,533...46,192,739
Ensembl chr 7:46,151,293...46,192,734 		JBrowse link
G E2f8 E2F transcription factor 8 decreases expression ISO Niclosamide results in decreased expression of E2F8 mRNA CTD PMID:28284560 PMID:36318118 NCBI chr 1:98,565,717...98,584,265
Ensembl chr 1:98,565,717...98,584,098 		JBrowse link
G Eaf2 ELL associated factor 2 decreases expression ISO Niclosamide results in decreased expression of EAF2 mRNA CTD PMID:36318118 NCBI chr11:63,960,200...64,004,610
Ensembl chr11:63,960,200...64,004,610 		JBrowse link
G Ebf1 EBF transcription factor 1 decreases expression ISO Niclosamide results in decreased expression of EBF1 mRNA CTD PMID:27226553 NCBI chr10:29,095,858...29,489,142
Ensembl chr10:29,099,933...29,487,665 		JBrowse link
G Ebf4 EBF family member 4 increases expression ISO Niclosamide results in increased expression of EBF4 mRNA CTD PMID:36318118 NCBI chr 3:117,498,186...117,566,566
Ensembl chr 3:117,498,319...117,566,566 		JBrowse link
G Echdc1 ethylmalonyl-CoA decarboxylase 1 decreases expression ISO Niclosamide results in decreased expression of ECHDC1 mRNA CTD PMID:22576131 NCBI chr 1:28,476,354...28,507,173
Ensembl chr 1:28,476,200...28,507,319 		JBrowse link
G Echdc2 enoyl CoA hydratase domain containing 2 decreases expression ISO Niclosamide results in decreased expression of ECHDC2 mRNA CTD PMID:36318118 NCBI chr 5:122,915,874...122,934,860
Ensembl chr 5:122,916,134...122,934,859 		JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 decreases expression ISO Niclosamide results in decreased expression of ECHS1 mRNA CTD PMID:22576131 NCBI chr 1:194,895,036...194,903,863
Ensembl chr 1:194,895,036...194,903,884 		JBrowse link
G Efna1 ephrin A1 increases expression ISO Niclosamide results in increased expression of EFNA1 mRNA CTD PMID:36318118 NCBI chr 2:174,681,676...174,689,061
Ensembl chr 2:174,681,682...174,690,866 		JBrowse link
G Efna3 ephrin A3 increases expression ISO Niclosamide results in increased expression of EFNA3 mRNA CTD PMID:36318118 NCBI chr 2:174,729,192...174,738,111
Ensembl chr 2:174,729,764...174,738,736 		JBrowse link
G Efnb3 ephrin B3 increases expression ISO Niclosamide results in increased expression of EFNB3 mRNA CTD PMID:36318118 NCBI chr10:54,274,506...54,281,951
Ensembl chr10:54,274,506...54,280,471 		JBrowse link
G Egf epidermal growth factor decreases expression
multiple interactions		 ISO Niclosamide results in decreased expression of EGF mRNA; Niclosamide results in decreased expression of EGF protein
Niclosamide inhibits the reaction [EGF protein results in increased expression of HIF1A mRNA]; Niclosamide inhibits the reaction [EGF protein results in increased phosphorylation of STAT3 protein]		 CTD PMID:30779072 NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064 		JBrowse link
G Egfr epidermal growth factor receptor decreases expression
decreases phosphorylation		 ISO Niclosamide analog results in decreased expression of EGFR protein; Niclosamide results in decreased expression of EGFR mRNA; Niclosamide results in decreased expression of EGFR protein
Niclosamide results in decreased phosphorylation of EGFR protein		 CTD PMID:28284560 PMID:28426875 PMID:30779072 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Egr1 early growth response 1 increases expression
decreases expression		 ISO Niclosamide results in increased expression of EGR1 mRNA
Niclosamide results in decreased expression of EGR1 mRNA		 CTD PMID:28284560 PMID:36318118 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases expression
multiple interactions		 ISO Niclosamide results in increased expression of EIF2AK3 mRNA
ATF3 protein affects the reaction [Niclosamide results in increased expression of EIF2AK3 mRNA]; Niclosamide results in increased expression of and results in increased phosphorylation of EIF2AK3 protein		 CTD PMID:26917416 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation ISO Niclosamide results in increased phosphorylation of EIF2S1 protein CTD PMID:26917416 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225 		JBrowse link
G Eif4a2 eukaryotic translation initiation factor 4A2 increases expression ISO Niclosamide results in increased expression of EIF4A2 mRNA CTD PMID:36318118 NCBI chr11:77,764,126...77,770,810
Ensembl chr11:77,764,124...77,770,781 		JBrowse link
G Eif4e eukaryotic translation initiation factor 4E multiple interactions ISO Niclosamide promotes the reaction [EIF4E protein binds to EIF4EBP1 protein] CTD PMID:19771169 NCBI chr 2:227,066,519...227,099,261
Ensembl chr 2:227,066,673...227,098,683 		JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 decreases expression
decreases phosphorylation
multiple interactions		 ISO Niclosamide analog results in decreased expression of EIF4EBP1 protein modified form; Niclosamide results in decreased expression of EIF4EBP1 protein modified form
Niclosamide results in decreased phosphorylation of EIF4EBP1 protein
Niclosamide inhibits the reaction [MTOR protein results in increased phosphorylation of EIF4EBP1 protein]; Niclosamide promotes the reaction [EIF4E protein binds to EIF4EBP1 protein]		 CTD PMID:19771169 PMID:28284560 PMID:30258081 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984 		JBrowse link
G Elf1 E74 like ETS transcription factor 1 increases expression ISO Niclosamide results in increased expression of ELF1 mRNA CTD PMID:36318118 NCBI chr15:54,890,644...54,986,721
Ensembl chr15:54,865,616...54,986,699 		JBrowse link
G Elfn1 extracellular leucine-rich repeat and fibronectin type III domain containing 1 increases expression ISO Niclosamide results in increased expression of ELFN1 mRNA CTD PMID:36318118 NCBI chr12:14,660,049...14,725,709
Ensembl chr12:14,660,083...14,724,580 		JBrowse link
G Eml2 EMAP like 2 increases expression ISO Niclosamide results in increased expression of EML2 mRNA CTD PMID:36318118 NCBI chr 1:78,827,595...78,859,342
Ensembl chr 1:78,828,080...78,859,341 		JBrowse link
G Endod1 endonuclease domain containing 1 multiple interactions ISO Niclosamide inhibits the reaction [PIK3CA protein modified form results in increased expression of ENDOD1 mRNA] CTD PMID:27542212 NCBI chr 8:11,209,113...11,238,507
Ensembl chr 8:11,211,110...11,238,892 		JBrowse link
G Eng endoglin increases expression ISO Niclosamide results in increased expression of ENG mRNA CTD PMID:36318118 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230 		JBrowse link
G Eno2 enolase 2 increases expression ISO Niclosamide results in increased expression of ENO2 mRNA CTD PMID:22576131 NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980 		JBrowse link
G Eno3 enolase 3 decreases expression ISO Niclosamide results in decreased expression of ENO3 mRNA CTD PMID:22576131 NCBI chr10:55,370,531...55,375,921
Ensembl chr10:55,366,975...55,375,921 		JBrowse link
G Ep300 E1A binding protein p300 increases expression ISO Niclosamide results in increased expression of EP300 mRNA CTD PMID:22576131 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088 		JBrowse link
G Epas1 endothelial PAS domain protein 1 multiple interactions ISO Niclosamide inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein] CTD PMID:36318118 NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228 		JBrowse link
G Epha8 Eph receptor A8 increases expression ISO Niclosamide results in increased expression of EPHA8 mRNA CTD PMID:36318118 NCBI chr 5:149,166,107...149,193,515
Ensembl chr 5:149,166,697...149,193,399 		JBrowse link
G Eps8l3 EPS8 like 3 increases expression ISO Niclosamide results in increased expression of EPS8L3 mRNA CTD PMID:28284560 NCBI chr 2:195,514,692...195,528,085
Ensembl chr 2:195,514,692...195,528,085 		JBrowse link
G Ethe1 ETHE1, persulfide dioxygenase increases expression ISO Niclosamide results in increased expression of ETHE1 mRNA CTD PMID:36318118 NCBI chr 1:80,184,037...80,199,092
Ensembl chr 1:80,183,894...80,199,052 		JBrowse link
G Eva1b eva-1 homolog B increases expression ISO Niclosamide results in increased expression of EVA1B mRNA CTD PMID:36318118 NCBI chr 5:138,427,088...138,429,602
Ensembl chr 5:138,427,151...138,432,433 		JBrowse link
G Exo5 exonuclease 5 decreases expression ISO Niclosamide results in decreased expression of EXO5 mRNA CTD PMID:36318118 NCBI chr 5:134,494,440...134,497,757
Ensembl chr 5:134,493,829...134,497,772 		JBrowse link
G Exog exo/endonuclease G decreases expression ISO Niclosamide results in decreased expression of EXOG mRNA CTD PMID:36318118 NCBI chr 8:119,184,974...119,204,819
Ensembl chr 8:119,185,136...119,204,672 		JBrowse link
G F10 coagulation factor X increases expression ISO Niclosamide results in increased expression of F10 mRNA CTD PMID:36318118 NCBI chr16:76,468,834...76,488,141
Ensembl chr16:76,468,838...76,488,141 		JBrowse link
G F12 coagulation factor XII increases expression ISO Niclosamide results in increased expression of F12 mRNA CTD PMID:36318118 NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530 		JBrowse link
G Fam131c family with sequence similarity 131, member C increases expression ISO Niclosamide results in increased expression of FAM131C mRNA CTD PMID:36318118 NCBI chr 5:153,674,459...153,690,791
Ensembl chr 5:153,671,772...153,690,800 		JBrowse link
G Fam135b family with sequence similarity 135, member B increases expression ISO Niclosamide results in increased expression of FAM135B mRNA CTD PMID:36318118 NCBI chr 7:103,380,981...103,649,802
Ensembl chr 7:103,386,915...103,649,708 		JBrowse link
G Fam13b family with sequence similarity 13, member B decreases expression ISO Niclosamide results in decreased expression of FAM13B mRNA CTD PMID:36318118 NCBI chr18:26,040,285...26,107,112
Ensembl chr18:26,040,285...26,106,587 		JBrowse link
G Fam221a family with sequence similarity 221, member A increases expression ISO Niclosamide results in increased expression of FAM221A mRNA CTD PMID:36318118 NCBI chr 4:78,337,296...78,358,918
Ensembl chr 4:78,337,296...78,358,909 		JBrowse link
G Fam43a family with sequence similarity 43, member A increases expression ISO Niclosamide results in increased expression of FAM43A mRNA CTD PMID:36318118 NCBI chr11:70,128,253...70,131,401
Ensembl chr11:70,128,253...70,131,401 		JBrowse link
G Fam43b family with sequence similarity 43, member B increases expression ISO Niclosamide results in increased expression of FAM43B mRNA CTD PMID:36318118 NCBI chr 5:150,610,656...150,613,054
Ensembl chr 5:150,611,609...150,612,601 		JBrowse link
G Fam83d family with sequence similarity 83, member D decreases expression ISO Niclosamide results in decreased expression of FAM83D mRNA CTD PMID:28284560 NCBI chr 3:147,421,941...147,441,211
Ensembl chr 3:147,421,908...147,441,192 		JBrowse link
G Fancb FA complementation group B decreases expression ISO Niclosamide results in decreased expression of FANCB mRNA CTD PMID:36318118 NCBI chr  X:29,403,771...29,420,484
Ensembl chr  X:29,403,771...29,420,192 		JBrowse link
G Fas Fas cell surface death receptor multiple interactions ISO
EXP		 Niclosamide affects the reaction [FAS protein mutant form affects the expression of BCL6 mRNA]; Niclosamide affects the reaction [FAS protein mutant form affects the expression of BCL6 protein]; Niclosamide affects the reaction [FAS protein mutant form affects the expression of CXCR5 mRNA]; Niclosamide affects the reaction [FAS protein mutant form affects the expression of IL21 protein]; Niclosamide affects the reaction [FAS protein mutant form affects the expression of IL6 protein]; Niclosamide affects the reaction [FAS protein mutant form affects the expression of PRDM1 mRNA]; Niclosamide affects the reaction [FAS protein mutant form affects the expression of TCF7 protein]; Niclosamide affects the reaction [FAS protein mutant form affects the phosphorylation of STAT3 protein]; Niclosamide inhibits the reaction [Doxorubicin results in increased expression of FAS mRNA]
Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of FAS mRNA]		 CTD PMID:28318631 PMID:33632240 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Fastkd3 FAST kinase domains 3 decreases expression ISO Niclosamide results in decreased expression of FASTKD3 mRNA CTD PMID:36318118 NCBI chr 1:34,858,342...34,866,988
Ensembl chr 1:34,858,219...34,866,973 		JBrowse link
G Fbxo2 F-box protein 2 increases expression ISO Niclosamide results in increased expression of FBXO2 mRNA CTD PMID:36318118 NCBI chr 5:158,592,926...158,598,355
Ensembl chr 5:158,592,925...158,598,355 		JBrowse link
G Fbxo48 F-box protein 48 increases expression ISO Niclosamide results in increased expression of FBXO48 mRNA CTD PMID:36318118 NCBI chr14:91,380,857...91,382,314
Ensembl chr14:91,380,857...91,382,314 		JBrowse link
G Fcho1 FCH and mu domain containing endocytic adaptor 1 increases expression ISO Niclosamide results in increased expression of FCHO1 mRNA CTD PMID:36318118 NCBI chr16:18,413,452...18,430,795
Ensembl chr16:18,413,363...18,435,104 		JBrowse link
G Fcrlb Fc receptor-like B increases expression ISO Niclosamide results in increased expression of FCRLB mRNA CTD PMID:36318118 NCBI chr13:83,148,685...83,157,157
Ensembl chr13:83,149,751...83,155,957 		JBrowse link
G Fen1 flap structure-specific endonuclease 1 decreases expression ISO Niclosamide results in decreased expression of FEN1 mRNA CTD PMID:36318118 NCBI chr 1:206,845,126...206,849,821
Ensembl chr 1:206,844,884...206,850,003 		JBrowse link
G Fgd1 FYVE, RhoGEF and PH domain containing 1 increases expression ISO Niclosamide results in increased expression of FGD1 mRNA CTD PMID:36318118 NCBI chr  X:20,023,746...20,066,734
Ensembl chr  X:20,023,746...20,066,566 		JBrowse link
G Fgf1 fibroblast growth factor 1 decreases expression ISO Niclosamide results in decreased expression of FGF1 mRNA; Niclosamide results in decreased expression of FGF1 protein CTD PMID:25174399 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357 		JBrowse link
G Fgf19 fibroblast growth factor 19 increases expression ISO Niclosamide results in increased expression of FGF19 mRNA CTD PMID:36318118 NCBI chr 1:200,056,526...200,060,980
Ensembl chr 1:200,056,644...200,060,287 		JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 increases expression ISO Niclosamide results in increased expression of FGFR4 mRNA CTD PMID:36318118 NCBI chr17:9,461,541...9,476,268
Ensembl chr17:9,461,547...9,476,242 		JBrowse link
G Fignl1 fidgetin-like 1 decreases expression ISO Niclosamide results in decreased expression of FIGNL1 mRNA CTD PMID:36318118 NCBI chr14:86,368,670...86,381,728
Ensembl chr14:86,368,675...86,377,455 		JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 multiple interactions
decreases expression		 ISO [Niclosamide co-treated with bicalutamide] results in decreased expression of FKBP5 mRNA
Niclosamide results in decreased expression of FKBP5 mRNA		 CTD PMID:28500234 NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674 		JBrowse link
G Flrt3 fibronectin leucine rich transmembrane protein 3 decreases expression ISO Niclosamide results in decreased expression of FLRT3 mRNA CTD PMID:36318118 NCBI chr 3:127,994,491...128,008,137
Ensembl chr 3:127,994,226...128,007,841 		JBrowse link
G Fmn1 formin 1 increases expression ISO Niclosamide results in increased expression of FMN1 mRNA CTD PMID:36318118 NCBI chr 3:100,101,103...100,485,652
Ensembl chr 3:100,134,549...100,479,220 		JBrowse link
G Fn1 fibronectin 1 multiple interactions ISO Niclosamide inhibits the reaction [Doxorubicin results in increased expression of FN1 protein]
HIPK2 protein inhibits the reaction [Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of FN1 mRNA]]; Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of FN1 mRNA]		 CTD PMID:28318631 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Fndc10 fibronectin type III domain containing 10 increases expression ISO Niclosamide results in increased expression of FNDC10 mRNA CTD PMID:36318118 NCBI chr 5:166,299,587...166,311,477
Ensembl chr 5:166,300,122...166,310,326 		JBrowse link
G Fndc4 fibronectin type III domain containing 4 increases expression ISO Niclosamide results in increased expression of FNDC4 mRNA CTD PMID:36318118 NCBI chr 6:25,077,155...25,080,812
Ensembl chr 6:25,077,349...25,080,675 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of FOS mRNA]
Niclosamide inhibits the reaction [TNFSF11 protein results in increased expression of FOS protein]		 CTD PMID:26792726 PMID:28824321 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit increases expression ISO Niclosamide results in increased expression of FOSB mRNA CTD PMID:28284560 NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465 		JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression ISO Niclosamide results in increased expression of FOSL1 mRNA CTD PMID:22576131 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930 		JBrowse link
G Foxl1 forkhead box L1 increases expression ISO Niclosamide results in increased expression of FOXL1 mRNA CTD PMID:36318118 NCBI chr19:49,197,269...49,200,682
Ensembl chr19:49,197,400...49,198,425 		JBrowse link
G Foxm1 forkhead box M1 multiple interactions
decreases expression		 ISO Imatinib Mesylate promotes the reaction [Niclosamide results in decreased expression of FOXM1 protein]; Niclosamide inhibits the reaction [TNF protein affects the localization of FOXM1 protein]; Niclosamide promotes the reaction [Imatinib Mesylate results in decreased expression of FOXM1 protein] CTD PMID:27492973 NCBI chr 4:161,639,538...161,652,012
Ensembl chr 4:161,638,816...161,650,684 		JBrowse link
G Foxo4 forkhead box O4 increases expression ISO Niclosamide results in increased expression of FOXO4 mRNA CTD PMID:36318118 NCBI chr  X:66,385,241...66,392,115
Ensembl chr  X:66,385,558...66,392,115 		JBrowse link
G Foxo6 forkhead box O6 increases expression ISO Niclosamide results in increased expression of FOXO6 mRNA CTD PMID:36318118 NCBI chr 5:133,856,087...133,876,387
Ensembl chr 5:133,856,072...133,876,573 		JBrowse link
G Frat2 FRAT regulator of WNT signaling pathway 2 increases expression ISO Niclosamide results in increased expression of FRAT2 mRNA CTD PMID:36318118 NCBI chr 1:240,654,120...240,656,449
Ensembl chr 1:240,654,137...240,656,517 		JBrowse link
G Frzb frizzled-related protein increases expression ISO Niclosamide results in increased expression of FRZB mRNA CTD PMID:36318118 NCBI chr 3:65,332,274...65,365,208
Ensembl chr 3:65,332,277...65,365,208 		JBrowse link
G Fscn1 fascin actin-bundling protein 1 multiple interactions ISO Niclosamide inhibits the reaction [Adenosine Triphosphate results in increased expression of FSCN1 mRNA] CTD PMID:29733962 NCBI chr12:11,597,042...11,610,183
Ensembl chr12:11,597,048...11,610,211 		JBrowse link
G Fstl3 follistatin like 3 increases expression ISO Niclosamide results in increased expression of FSTL3 mRNA CTD PMID:36318118 NCBI chr 7:9,923,574...9,929,223
Ensembl chr 7:9,923,576...9,939,639 		JBrowse link
G Fzd1 frizzled class receptor 1 affects localization ISO Niclosamide affects the localization of FZD1 protein CTD PMID:19772353 NCBI chr 4:29,310,303...29,314,701
Ensembl chr 4:29,310,091...29,312,643
Ensembl chr 4:29,310,091...29,312,643 		JBrowse link
G Fzd2 frizzled class receptor 2 decreases expression
increases expression		 ISO Niclosamide results in decreased expression of FZD2 mRNA
Niclosamide results in increased expression of FZD2 mRNA		 CTD PMID:22576131 PMID:36318118 NCBI chr10:87,561,866...87,563,776
Ensembl chr10:87,561,326...87,565,334 		JBrowse link
G Fzd5 frizzled class receptor 5 increases expression ISO Niclosamide results in increased expression of FZD5 mRNA CTD PMID:22576131 NCBI chr 9:66,113,096...66,120,276
Ensembl chr 9:66,113,112...66,121,457 		JBrowse link
G Fzd9 frizzled class receptor 9 decreases expression ISO Niclosamide results in decreased expression of FZD9 mRNA CTD PMID:22576131 NCBI chr12:21,427,084...21,429,398
Ensembl chr12:21,427,084...21,429,398 		JBrowse link
G G4 G4 protein affects expression ISO Niclosamide affects the expression of C6ORF47 mRNA CTD PMID:36318118 NCBI chr20:3,693,691...3,696,194
Ensembl chr20:3,693,649...3,696,088 		JBrowse link
G Gab2 GRB2-associated binding protein 2 increases expression ISO Niclosamide results in increased expression of GAB2 mRNA CTD PMID:36318118 NCBI chr 1:151,429,844...151,625,708
Ensembl chr 1:151,429,695...151,625,031 		JBrowse link
G Gabarapl1 GABA type A receptor associated protein like 1 increases expression ISO Niclosamide results in increased expression of GABARAPL1 mRNA CTD PMID:36318118 NCBI chr 4:162,980,309...162,989,452
Ensembl chr 4:162,980,249...162,989,450 		JBrowse link
G Gabra4 gamma-aminobutyric acid type A receptor subunit alpha 4 increases expression ISO Niclosamide results in increased expression of GABRA4 mRNA CTD PMID:36318118 NCBI chr14:36,590,782...36,667,724
Ensembl chr14:36,590,782...36,665,844 		JBrowse link
G Gabrb1 gamma-aminobutyric acid type A receptor subunit beta1 increases expression ISO Niclosamide results in increased expression of GABRB1 mRNA CTD PMID:36318118 NCBI chr14:36,068,725...36,548,946
Ensembl chr14:36,080,393...36,548,948 		JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta increases expression ISO Niclosamide results in increased expression of GADD45B mRNA CTD PMID:36318118 NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046 		JBrowse link
G Garin1a golgi associated RAB2 interactor 1A increases expression ISO Niclosamide results in increased expression of GARIN1A mRNA CTD PMID:36318118 NCBI chr 4:57,880,019...57,890,824
Ensembl chr 4:57,880,019...57,890,820 		JBrowse link
G Gata5 GATA binding protein 5 increases expression ISO Niclosamide results in increased expression of GATA5 mRNA CTD PMID:36318118 NCBI chr 3:167,418,563...167,426,751
Ensembl chr 3:167,418,565...167,426,751 		JBrowse link
G Gcg glucagon multiple interactions EXP Niclosamide inhibits the reaction [GCG protein results in increased abundance of Cyclic AMP]; Niclosamide inhibits the reaction [GCG protein results in increased expression of CCND1 mRNA]; Niclosamide inhibits the reaction [GCG protein results in increased expression of CCND1 protein]; Niclosamide inhibits the reaction [GCG protein results in increased expression of MYC mRNA]; Niclosamide inhibits the reaction [GCG protein results in increased phosphorylation of CTNNB1 protein] CTD PMID:26964897 NCBI chr 3:47,113,914...47,122,958
Ensembl chr 3:47,113,914...47,122,929 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit decreases expression ISO Niclosamide results in decreased expression of GCLM mRNA CTD PMID:36318118 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO Niclosamide results in increased expression of GDF15 mRNA CTD PMID:36318118 NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055 		JBrowse link
G Gdpd5 glycerophosphodiester phosphodiesterase domain containing 5 increases expression ISO Niclosamide results in increased expression of GDPD5 mRNA CTD PMID:36318118 NCBI chr 1:153,679,718...153,761,452
Ensembl chr 1:153,679,718...153,761,446 		JBrowse link
G Gdpgp1 GDP-D-glucose phosphorylase 1 decreases expression ISO Niclosamide results in decreased expression of GDPGP1 mRNA CTD PMID:36318118 NCBI chr 1:134,184,119...134,193,281
Ensembl chr 1:134,183,696...134,219,783 		JBrowse link
G Gid4 GID complex subunit 4 increases expression ISO Niclosamide results in increased expression of GID4 mRNA CTD PMID:36318118 NCBI chr10:45,221,556...45,247,627
Ensembl chr10:45,245,754...45,247,621
Ensembl chr10:45,245,754...45,247,621 		JBrowse link
G Gins1 GINS complex subunit 1 decreases expression ISO Niclosamide results in decreased expression of GINS1 mRNA CTD PMID:36318118 NCBI chr 3:139,724,513...139,745,930
Ensembl chr 3:139,724,490...139,745,936 		JBrowse link
G Gins2 GINS complex subunit 2 decreases expression ISO Niclosamide results in decreased expression of GINS2 mRNA CTD PMID:36318118 NCBI chr19:48,626,770...48,639,523
Ensembl chr19:48,626,770...48,639,339 		JBrowse link
G Gins3 GINS complex subunit 3 decreases expression ISO Niclosamide results in decreased expression of GINS3 mRNA CTD PMID:36318118 NCBI chr19:9,420,085...9,428,621
Ensembl chr19:9,420,086...9,428,687 		JBrowse link
G Gins4 GINS complex subunit 4 decreases expression ISO Niclosamide results in decreased expression of GINS4 mRNA CTD PMID:36318118 NCBI chr16:68,787,572...68,799,938
Ensembl chr16:68,767,339...68,802,273 		JBrowse link
G Glb1l3 galactosidase, beta 1-like 3 decreases expression ISO Niclosamide results in decreased expression of GLB1L3 mRNA CTD PMID:36318118 NCBI chr 8:25,179,165...25,220,904
Ensembl chr 8:25,179,165...25,220,904 		JBrowse link
G Glis1 GLIS family zinc finger 1 increases expression ISO Niclosamide results in increased expression of GLIS1 mRNA CTD PMID:36318118 NCBI chr 5:122,222,155...122,412,141
Ensembl chr 5:122,222,128...122,412,141 		JBrowse link
G Glis2 GLIS family zinc finger 2 increases expression ISO Niclosamide results in increased expression of GLIS2 mRNA CTD PMID:36318118 NCBI chr10:10,951,157...10,978,524
Ensembl chr10:10,951,371...10,971,578 		JBrowse link
G Gng7 G protein subunit gamma 7 increases expression ISO Niclosamide results in increased expression of GNG7 mRNA CTD PMID:36318118 NCBI chr 7:8,697,458...8,761,239
Ensembl chr 7:8,697,521...8,761,240 		JBrowse link
G Golga2 golgin A2 increases expression ISO Niclosamide results in increased expression of GOLGA2 mRNA CTD PMID:36318118 NCBI chr 3:15,583,862...15,604,279
Ensembl chr 3:15,584,039...15,604,279 		JBrowse link
G Gosr2 golgi SNAP receptor complex member 2 decreases expression ISO Niclosamide results in decreased expression of GOSR2 mRNA CTD PMID:36318118 NCBI chr10:88,585,291...88,605,642
Ensembl chr10:88,586,299...88,605,625 		JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 increases expression ISO Niclosamide results in increased expression of GOT2 mRNA CTD PMID:22576131 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994 		JBrowse link
G Gp1bb glycoprotein Ib platelet subunit beta increases expression ISO Niclosamide results in increased expression of GP1BB mRNA CTD PMID:36318118 NCBI chr11:82,378,216...82,379,393
Ensembl chr11:82,378,199...82,379,392 		JBrowse link
G Gpc2 glypican 2 increases expression ISO Niclosamide results in increased expression of GPC2 mRNA CTD PMID:36318118 NCBI chr12:17,277,875...17,284,297
Ensembl chr12:17,277,875...17,284,208 		JBrowse link
G Gpr153 G protein-coupled receptor 153 increases expression ISO Niclosamide results in increased expression of GPR153 mRNA CTD PMID:36318118 NCBI chr 5:162,781,587...162,792,975
Ensembl chr 5:162,781,587...162,792,971 		JBrowse link
G Gpr75 G protein-coupled receptor 75 decreases expression ISO Niclosamide results in decreased expression of GPR75 mRNA CTD PMID:36318118 NCBI chr14:104,609,542...104,618,885
Ensembl chr14:104,611,089...104,620,370 		JBrowse link
G Gprc5c G protein-coupled receptor, class C, group 5, member C increases expression ISO Niclosamide results in increased expression of GPRC5C mRNA CTD PMID:36318118 NCBI chr10:99,886,900...99,908,928
Ensembl chr10:99,887,077...99,908,926 		JBrowse link
G Grem2 gremlin 2, DAN family BMP antagonist decreases expression ISO Niclosamide results in decreased expression of GREM2 mRNA CTD PMID:36318118 NCBI chr13:86,778,543...86,871,509
Ensembl chr13:86,778,500...86,871,615 		JBrowse link
G Grik5 glutamate ionotropic receptor kainate type subunit 5 increases expression ISO Niclosamide results in increased expression of GRIK5 mRNA CTD PMID:36318118 NCBI chr 1:80,605,878...80,667,896
Ensembl chr 1:80,605,892...80,667,125 		JBrowse link
G Grin2d glutamate ionotropic receptor NMDA type subunit 2D increases expression ISO Niclosamide results in increased expression of GRIN2D mRNA CTD PMID:36318118 NCBI chr 1:96,306,871...96,346,994
Ensembl chr 1:96,308,365...96,344,793 		JBrowse link
G Grip2 glutamate receptor interacting protein 2 increases expression ISO Niclosamide results in increased expression of GRIP2 mRNA CTD PMID:36318118 NCBI chr 4:124,271,456...124,356,538
Ensembl chr 4:124,271,456...124,321,268 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases expression
decreases phosphorylation
increases phosphorylation		 ISO Niclosamide results in decreased expression of GSK3B mRNA
Niclosamide results in decreased phosphorylation of GSK3B protein
Niclosamide results in increased phosphorylation of GSK3B protein		 CTD PMID:22576131 PMID:30143678 PMID:35115509 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Gstt2 glutathione S-transferase theta 2 decreases expression ISO Niclosamide results in decreased expression of GSTT2 mRNA CTD PMID:36318118 NCBI chr20:12,819,617...12,823,288
Ensembl chr20:12,819,170...12,823,288 		JBrowse link
G Gtf2h4 general transcription factor 2H subunit 4 decreases expression
increases expression		 ISO Niclosamide results in decreased expression of GTF2H4 mRNA
Niclosamide results in increased expression of GTF2H4 mRNA		 CTD PMID:36318118 NCBI chr20:3,071,328...3,076,990
Ensembl chr20:3,071,328...3,076,984 		JBrowse link
G Gtse1 G-2 and S-phase expressed 1 decreases expression ISO Niclosamide results in decreased expression of GTSE1 mRNA CTD PMID:28284560 NCBI chr 7:116,949,997...116,966,826
Ensembl chr 7:116,950,053...116,966,806 		JBrowse link
G Gxylt2 glucoside xylosyltransferase 2 increases expression ISO Niclosamide results in increased expression of GXYLT2 mRNA CTD PMID:36318118 NCBI chr 4:133,347,230...133,449,708
Ensembl chr 4:133,347,499...133,449,454 		JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase decreases expression ISO Niclosamide results in decreased expression of HADH mRNA CTD PMID:22576131 NCBI chr 2:219,787,935...219,830,335
Ensembl chr 2:219,787,927...219,830,353 		JBrowse link
G Hamp hepcidin antimicrobial peptide decreases expression
increases expression		 ISO Niclosamide results in decreased expression of HAMP mRNA
Niclosamide results in increased expression of HAMP mRNA		 CTD PMID:25633564 PMID:28284560 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891 		JBrowse link
G Hbp1 HMG-box transcription factor 1 multiple interactions
increases expression		 ISO Niclosamide inhibits the reaction [PIK3CA protein modified form results in decreased expression of HBP1 mRNA]
Niclosamide results in increased expression of HBP1 mRNA		 CTD PMID:27542212 PMID:36318118 NCBI chr 6:48,529,633...48,555,775
Ensembl chr 6:48,529,372...48,555,787 		JBrowse link
G Hdac5 histone deacetylase 5 increases expression ISO Niclosamide results in increased expression of HDAC5 mRNA CTD PMID:36318118 NCBI chr10:87,152,978...87,187,921
Ensembl chr10:87,152,978...87,188,235 		JBrowse link
G Helz2 helicase with zinc finger 2 increases expression ISO Niclosamide results in increased expression of HELZ2 mRNA CTD PMID:36318118 NCBI chr 3:168,338,813...168,353,219
Ensembl chr 3:168,338,813...168,353,159 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 decreases expression
multiple interactions		 ISO
EXP		 Niclosamide results in decreased expression of HES1 protein
Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of HES1 mRNA]; Niclosamide inhibits the reaction [Thioacetamide results in increased expression of HES1 mRNA]; Poloxamer promotes the reaction [Niclosamide inhibits the reaction [Thioacetamide results in increased expression of HES1 mRNA]]
Niclosamide inhibits the reaction [Doxorubicin results in increased expression of HES1 mRNA]		 CTD PMID:19160421 PMID:28318631 PMID:32961231 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 multiple interactions ISO
EXP		 Niclosamide inhibits the reaction [Doxorubicin results in increased expression of HEY1 mRNA]
Niclosamide inhibits the reaction [PIK3CA protein modified form results in decreased expression of HEY1 mRNA]
Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of HEY1 mRNA]		 CTD PMID:27542212 PMID:28318631 NCBI chr 2:93,096,605...93,100,316
Ensembl chr 2:93,095,498...93,100,312 		JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 multiple interactions
increases expression		 EXP
ISO		 Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of HEY2 mRNA]
Niclosamide results in increased expression of HEY2 mRNA
N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [Niclosamide results in increased expression of HEY2 mRNA]
Niclosamide inhibits the reaction [Doxorubicin results in increased expression of HEY2 mRNA]		 CTD PMID:19160421 PMID:28318631 NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218 		JBrowse link
G Hhipl1 HHIP-like 1 increases expression ISO Niclosamide results in increased expression of HHIPL1 mRNA CTD PMID:36318118 NCBI chr 6:127,219,616...127,243,839
Ensembl chr 6:127,220,014...127,242,564 		JBrowse link
G Hid1 HID1 domain containing increases expression ISO Niclosamide results in increased expression of HID1 mRNA CTD PMID:36318118 NCBI chr10:100,589,555...100,610,050
Ensembl chr10:100,589,555...100,610,041 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha decreases expression
multiple interactions		 ISO Niclosamide results in decreased expression of HIF1A mRNA; Niclosamide results in decreased expression of HIF1A protein
Niclosamide inhibits the reaction [EGF protein results in increased expression of HIF1A mRNA]; Niclosamide inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]		 CTD PMID:30779072 PMID:36318118 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 multiple interactions ISO
EXP		 Niclosamide inhibits the reaction [Doxorubicin results in increased expression of HIPK2 mRNA]; Niclosamide inhibits the reaction [Doxorubicin results in increased expression of HIPK2 protein]
Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of HIPK2 mRNA]; Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of HIPK2 protein]
HIPK2 protein inhibits the reaction [Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of FN1 mRNA]]; HIPK2 protein inhibits the reaction [Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of VIM mRNA]]; HIPK2 protein inhibits the reaction [Niclosamide inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein]]; Niclosamide inhibits the reaction [TGFB1 protein promotes the reaction [SMAD3 protein binds to HIPK2 promoter]]; Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of HIPK2 protein]		 CTD PMID:28318631 NCBI chr 4:67,439,327...67,619,223
Ensembl chr 4:67,440,501...67,619,223 		JBrowse link
G Hist1h2bc histone cluster 1, H2bc increases expression ISO Niclosamide results in increased expression of H2BC21 mRNA CTD PMID:36318118 NCBI chr17:42,692,335...42,696,601
Ensembl chr17:42,694,723...42,696,642 		JBrowse link
G Hivep2 HIVEP zinc finger 2 increases expression ISO Niclosamide results in increased expression of HIVEP2 mRNA CTD PMID:36318118 NCBI chr 1:8,358,205...8,555,993
Ensembl chr 1:8,359,289...8,555,993 		JBrowse link
G Hk3 hexokinase 3 decreases expression ISO Niclosamide results in decreased expression of HK3 mRNA CTD PMID:36318118 NCBI chr17:9,596,950...9,614,847
Ensembl chr17:9,599,865...9,614,863 		JBrowse link
G Hmgcl 3-hydroxy-3-methylglutaryl-CoA lyase increases expression ISO Niclosamide results in increased expression of HMGCL mRNA CTD PMID:36318118 NCBI chr 5:148,178,203...148,192,072
Ensembl chr 5:148,178,252...148,192,068 		JBrowse link
G Hmmr hyaluronan-mediated motility receptor decreases expression ISO Niclosamide results in decreased expression of HMMR mRNA CTD PMID:28284560 NCBI chr10:25,132,933...25,163,029
Ensembl chr10:25,132,977...25,163,060 		JBrowse link
G Hmx2 H6 family homeobox 2 increases expression ISO Niclosamide results in increased expression of HMX2 mRNA CTD PMID:36318118 NCBI chr 1:186,319,110...186,326,771
Ensembl chr 1:186,319,110...186,326,771 		JBrowse link
G Hoga1 4-hydroxy-2-oxoglutarate aldolase 1 increases expression ISO Niclosamide results in increased expression of HOGA1 mRNA CTD PMID:36318118 NCBI chr 1:240,856,991...240,884,243
Ensembl chr 1:240,857,126...240,884,568 		JBrowse link
G Homer1 homer scaffold protein 1 decreases expression ISO Niclosamide results in decreased expression of HOMER1 mRNA CTD PMID:36318118 NCBI chr 2:24,542,777...24,645,715
Ensembl chr 2:24,543,093...24,644,785 		JBrowse link
G Homer3 homer scaffold protein 3 increases expression ISO Niclosamide results in increased expression of HOMER3 mRNA CTD PMID:36318118 NCBI chr16:19,132,177...19,142,739
Ensembl chr16:19,132,162...19,142,680 		JBrowse link
G Hoxa1 homeobox A1 increases expression ISO Niclosamide results in increased expression of HOXA1 CTD PMID:26820057 NCBI chr 4:81,255,814...81,258,587
Ensembl chr 4:81,255,883...81,258,504 		JBrowse link
G Hr HR, lysine demethylase and nuclear receptor corepressor increases expression ISO Niclosamide results in increased expression of HR mRNA CTD PMID:36318118 NCBI chr15:45,626,835...45,646,313
Ensembl chr15:45,626,835...45,646,313 		JBrowse link
G Hrh1 histamine receptor H 1 increases expression ISO Niclosamide results in increased expression of HRH1 mRNA CTD PMID:36318118 NCBI chr 4:147,564,963...147,649,353
Ensembl chr 4:147,645,995...147,647,455 		JBrowse link
G Hs6st1 heparan sulfate 6-O-sulfotransferase 1 decreases expression ISO Niclosamide results in decreased expression of HS6ST1 mRNA CTD PMID:36318118 NCBI chr 9:38,283,502...38,322,684
Ensembl chr 9:38,282,395...38,322,683 		JBrowse link
G Hsd17b14 hydroxysteroid (17-beta) dehydrogenase 14 increases expression ISO Niclosamide results in increased expression of HSD17B14 mRNA CTD PMID:36318118 NCBI chr 1:96,029,224...96,039,577
Ensembl chr 1:96,029,284...96,039,883 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 increases expression ISO Niclosamide results in increased expression of HSD3B1 mRNA CTD PMID:36318118 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999 		JBrowse link
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 increases expression ISO Niclosamide results in increased expression of HSD3B2 mRNA CTD PMID:36318118 NCBI chr 2:186,095,897...186,105,354
Ensembl chr 2:186,095,897...186,101,852 		JBrowse link
G Hspa6l-ps1 heat shock protein family A (Hsp70) member 6 like, pseudogene 1 increases expression ISO Niclosamide results in increased expression of HSPA6 mRNA CTD PMID:36318118 NCBI chr13:83,273,176...83,274,317 JBrowse link
G Hspb7 heat shock protein family B (small) member 7 increases expression ISO Niclosamide results in increased expression of HSPB7 mRNA CTD PMID:36318118 NCBI chr 5:153,727,782...153,731,268
Ensembl chr 5:153,727,588...153,731,266 		JBrowse link
G Hvcn1 hydrogen voltage-gated channel 1 increases expression ISO Niclosamide results in increased expression of HVCN1 mRNA CTD PMID:36318118 NCBI chr12:34,341,673...34,370,010
Ensembl chr12:34,335,190...34,370,141 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO
EXP		 Niclosamide inhibits the reaction [Doxorubicin results in increased expression of ICAM1 mRNA]
Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of ICAM1 mRNA]		 CTD PMID:28318631 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Icam5 intercellular adhesion molecule 5 increases expression ISO Niclosamide results in increased expression of ICAM5 mRNA CTD PMID:36318118 NCBI chr 8:19,567,390...19,575,588
Ensembl chr 8:19,568,600...19,575,588 		JBrowse link
G Id1 inhibitor of DNA binding 1 increases expression ISO Niclosamide results in increased expression of ID1 mRNA CTD PMID:36318118 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419 		JBrowse link
G Ier5l immediate early response 5-like increases expression ISO Niclosamide results in increased expression of IER5L mRNA CTD PMID:36318118 NCBI chr 3:13,744,056...13,745,647
Ensembl chr 3:13,744,078...13,745,647 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor affects response to substance ISO IGF1R protein affects the susceptibility to Niclosamide CTD PMID:27497986 NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777 		JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 increases expression ISO Niclosamide results in increased expression of IGFBP4 mRNA CTD PMID:36318118 NCBI chr10:83,995,253...84,007,272
Ensembl chr10:83,989,591...84,007,225 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta affects localization ISO Niclosamide affects the localization of IKBKB protein CTD PMID:26116531 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250 		JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma affects localization ISO Niclosamide affects the localization of IKBKG protein CTD PMID:26116531 NCBI chr  X:152,216,485...152,241,476
Ensembl chr  X:152,216,596...152,239,499 		JBrowse link
G Ikzf2 IKAROS family zinc finger 2 increases expression ISO Niclosamide results in increased expression of IKZF2 mRNA CTD PMID:36318118 NCBI chr 9:71,046,038...71,191,296
Ensembl chr 9:71,042,440...71,190,867 		JBrowse link
G Il12a interleukin 12A multiple interactions ISO Niclosamide inhibits the reaction [IL6 protein results in increased expression of IL12A mRNA] CTD PMID:26297436 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734 		JBrowse link
G Il17re interleukin 17 receptor E increases expression ISO Niclosamide results in increased expression of IL17RE mRNA CTD PMID:36318118 NCBI chr 4:146,604,547...146,618,206
Ensembl chr 4:146,605,526...146,618,206 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO Niclosamide inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of IL1B mRNA] CTD PMID:33524445 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il21 interleukin 21 multiple interactions ISO Niclosamide affects the reaction [FAS protein mutant form affects the expression of IL21 protein]; Niclosamide inhibits the reaction [resiquimod results in increased expression of IL21 protein] CTD PMID:33632240 NCBI chr 2:120,117,105...120,127,012
Ensembl chr 2:120,119,444...120,126,996 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO Niclosamide affects the reaction [FAS protein mutant form affects the expression of IL6 protein]; Niclosamide inhibits the reaction [Doxorubicin results in increased expression of IL6 mRNA]; Niclosamide inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; Niclosamide inhibits the reaction [resiquimod results in increased expression of IL6 protein]
Niclosamide inhibits the reaction [IL6 protein results in decreased susceptibility to enzalutamide]; Niclosamide inhibits the reaction [IL6 protein results in increased expression of APPA mRNA]; Niclosamide inhibits the reaction [IL6 protein results in increased expression of BIRC5 protein]; Niclosamide inhibits the reaction [IL6 protein results in increased expression of CCND1 mRNA]; Niclosamide inhibits the reaction [IL6 protein results in increased expression of IL12A mRNA]; Niclosamide inhibits the reaction [IL6 protein results in increased expression of MYC protein]; Niclosamide inhibits the reaction [IL6 protein results in increased expression of SOCS1A mRNA]; Niclosamide inhibits the reaction [IL6 protein results in increased expression of TGFB1A mRNA]; Niclosamide inhibits the reaction [IL6 protein results in increased phosphorylation of and results in increased activity of STAT3 protein]		 CTD PMID:24561310 PMID:25970160 PMID:26297436 PMID:28318631 PMID:33632240 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Inafm1 InaF-motif containing 1 increases expression ISO Niclosamide results in increased expression of INAFM1 mRNA CTD PMID:36318118 NCBI chr 1:76,976,808...76,978,292 JBrowse link
G Inca1 inhibitor of CDK, cyclin A1 interacting protein 1 increases expression ISO Niclosamide results in increased expression of INCA1 mRNA CTD PMID:36318118 NCBI chr10:55,401,989...55,414,364
Ensembl chr10:55,401,982...55,414,114 		JBrowse link
G Inhbe inhibin subunit beta E increases expression ISO Niclosamide results in increased expression of INHBE mRNA CTD PMID:36318118 NCBI chr 7:63,176,221...63,179,209
Ensembl chr 7:63,176,219...63,179,172 		JBrowse link
G Inpp5j inositol polyphosphate-5-phosphatase J increases expression ISO Niclosamide results in increased expression of INPP5J mRNA CTD PMID:36318118 NCBI chr14:78,374,161...78,385,305
Ensembl chr14:78,374,161...78,385,326 		JBrowse link
G Insrr insulin receptor-related receptor decreases expression ISO Niclosamide results in decreased expression of INSRR mRNA CTD PMID:36318118 NCBI chr 2:173,255,335...173,274,800
Ensembl chr 2:173,255,414...173,274,800 		JBrowse link
G Iqsec3 IQ motif and Sec7 domain ArfGEF 3 increases expression ISO Niclosamide results in increased expression of IQSEC3 mRNA CTD PMID:36318118 NCBI chr 4:154,610,933...154,707,310
Ensembl chr 4:154,610,934...154,707,310 		JBrowse link
G Irak2 interleukin-1 receptor-associated kinase 2 increases expression ISO Niclosamide results in increased expression of IRAK2 mRNA CTD PMID:36318118 NCBI chr 4:146,786,004...146,842,615
Ensembl chr 4:146,786,100...146,842,602 		JBrowse link
G Irf2bp2 interferon regulatory factor 2 binding protein 2 increases expression ISO Niclosamide results in increased expression of IRF2BP2 mRNA CTD PMID:36318118 NCBI chr19:54,559,417...54,565,096
Ensembl chr19:54,560,128...54,566,642 		JBrowse link
G Itgav integrin subunit alpha V multiple interactions ISO Niclosamide inhibits the reaction [TNFSF11 protein results in increased expression of ITGAV mRNA] CTD PMID:26792726 NCBI chr 3:68,838,514...68,926,653
Ensembl chr 3:68,838,189...68,926,639 		JBrowse link
G Itgb3 integrin subunit beta 3 multiple interactions ISO Niclosamide inhibits the reaction [TNFSF11 protein results in increased expression of ITGB3 mRNA]
Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of ITGB3 mRNA]		 CTD PMID:26792726 PMID:28824321 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679 		JBrowse link
G Jade2 jade family PHD finger 2 increases expression ISO Niclosamide results in increased expression of JADE2 mRNA CTD PMID:36318118 NCBI chr10:36,075,239...36,124,210
Ensembl chr10:36,078,917...36,116,984 		JBrowse link
G Jak3 Janus kinase 3 increases expression ISO Niclosamide results in increased expression of JAK3 mRNA CTD PMID:36318118 NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536 		JBrowse link
G Jakmip3 janus kinase and microtubule interacting protein 3 increases expression ISO Niclosamide results in increased expression of JAKMIP3 mRNA CTD PMID:36318118 NCBI chr 1:193,753,134...193,881,105
Ensembl chr 1:193,811,513...193,881,104 		JBrowse link
G Jdp2 Jun dimerization protein 2 increases expression ISO Niclosamide results in increased expression of JDP2 mRNA CTD PMID:36318118 NCBI chr 6:105,261,619...105,302,386
Ensembl chr 6:105,261,373...105,301,485 		JBrowse link
G Jph3 junctophilin 3 increases expression ISO Niclosamide results in increased expression of JPH3 mRNA CTD PMID:36318118 NCBI chr19:49,793,967...49,855,338
Ensembl chr19:49,793,092...49,855,338 		JBrowse link
G Jph4 junctophilin 4 increases expression ISO Niclosamide results in increased expression of JPH4 mRNA CTD PMID:36318118 NCBI chr15:28,579,579...28,588,903
Ensembl chr15:28,571,568...28,587,573 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit affects localization
increases expression
increases phosphorylation
multiple interactions		 EXP
ISO		 Niclosamide affects the localization of JUN protein
Niclosamide results in increased expression of JUN mRNA
Niclosamide results in increased phosphorylation of JUN protein
Acetylcysteine inhibits the reaction [Hydrogen Peroxide promotes the reaction [Niclosamide results in increased phosphorylation of JUN protein]]; Acetylcysteine inhibits the reaction [Niclosamide results in increased phosphorylation of JUN protein]; Hydrogen Peroxide promotes the reaction [Niclosamide results in increased phosphorylation of JUN protein]; JUN protein affects the reaction [Niclosamide results in increased cleavage of PARP1 protein]		 CTD PMID:24750999 PMID:27338550 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Kbtbd11 kelch repeat and BTB domain containing 11 increases expression ISO Niclosamide results in increased expression of KBTBD11 mRNA CTD PMID:36318118 NCBI chr16:74,618,291...74,638,010
Ensembl chr16:74,615,792...74,637,736 		JBrowse link
G Kcnf1 potassium voltage-gated channel modifier subfamily F member 1 increases expression ISO Niclosamide results in increased expression of KCNF1 mRNA CTD PMID:36318118 NCBI chr 6:39,962,301...39,964,979
Ensembl chr 6:39,962,307...39,964,979 		JBrowse link
G Kcnk13 potassium two pore domain channel subfamily K member 13 decreases expression ISO Niclosamide results in decreased expression of KCNK13 mRNA CTD PMID:36318118 NCBI chr 6:119,240,825...119,345,292
Ensembl chr 6:119,242,188...119,345,240 		JBrowse link
G Kcnn3 potassium calcium-activated channel subfamily N member 3 increases expression ISO Niclosamide results in increased expression of KCNN3 mRNA CTD PMID:36318118 NCBI chr 2:174,929,846...175,088,910
Ensembl chr 2:174,936,629...175,081,145 		JBrowse link
G Kcnv1 potassium voltage-gated channel modifier subfamily V member 1 decreases expression ISO Niclosamide results in decreased expression of KCNV1 mRNA CTD PMID:36318118 NCBI chr 7:76,260,695...76,269,170
Ensembl chr 7:76,260,695...76,269,170 		JBrowse link
G Kctd11 potassium channel tetramerization domain containing 11 increases expression ISO Niclosamide results in increased expression of KCTD11 mRNA CTD PMID:36318118 NCBI chr10:54,602,575...54,604,738
Ensembl chr10:54,599,754...54,604,760 		JBrowse link
G Kdelr3 KDEL endoplasmic reticulum protein retention receptor 3 increases expression ISO Niclosamide results in increased expression of KDELR3 mRNA CTD PMID:36318118 NCBI chr 7:111,079,236...111,089,463
Ensembl chr 7:111,079,218...111,101,600 		JBrowse link
G Kdm5b lysine demethylase 5B increases expression ISO Niclosamide results in increased expression of KDM5B mRNA CTD PMID:36318118 NCBI chr13:46,001,589...46,073,868
Ensembl chr13:46,002,542...46,073,872 		JBrowse link
G Kdm6b lysine demethylase 6B increases expression ISO Niclosamide results in increased expression of KDM6B mRNA CTD PMID:36318118 NCBI chr10:54,120,716...54,142,212
Ensembl chr10:54,121,848...54,130,794 		JBrowse link
G Kdm7a lysine demethylase 7A increases expression ISO Niclosamide results in increased expression of KDM7A mRNA CTD PMID:36318118 NCBI chr 4:67,899,407...67,974,264
Ensembl chr 4:67,904,307...67,966,998 		JBrowse link
G Khnyn KH and NYN domain containing increases expression ISO Niclosamide results in increased expression of KHNYN mRNA CTD PMID:36318118 NCBI chr15:29,365,399...29,379,650
Ensembl chr15:29,365,260...29,376,967 		JBrowse link
G Kiaa1614 KIAA1614 homolog decreases expression ISO Niclosamide results in decreased expression of KIAA1614 mRNA CTD PMID:36318118 NCBI chr13:67,388,916...67,427,392
Ensembl chr13:67,389,044...67,421,272 		JBrowse link
G Kif11 kinesin family member 11 decreases expression ISO Niclosamide results in decreased expression of KIF11 mRNA CTD PMID:28284560 NCBI chr 1:235,124,371...235,176,760
Ensembl chr 1:235,124,316...235,176,766 		JBrowse link
G Kif20a kinesin family member 20A decreases expression ISO Niclosamide results in decreased expression of KIF20A mRNA CTD PMID:28284560 NCBI chr18:26,230,294...26,238,780
Ensembl chr18:26,230,230...26,238,780 		JBrowse link
G Kifc1 kinesin family member C1 decreases expression ISO Niclosamide results in decreased expression of KIFC1 mRNA CTD PMID:28284560 NCBI chr20:4,998,832...5,017,107
Ensembl chr20:4,999,047...5,017,105 		JBrowse link
G Kirrel2 kirre like nephrin family adhesion molecule 2 increases expression ISO Niclosamide results in increased expression of KIRREL2 mRNA CTD PMID:36318118 NCBI chr 1:85,708,793...85,718,670
Ensembl chr 1:85,708,793...85,718,670 		JBrowse link
G Kiz kizuna centrosomal protein increases expression ISO Niclosamide results in increased expression of KIZ mRNA CTD PMID:36318118 NCBI chr 3:134,277,631...134,385,260
Ensembl chr 3:134,277,687...134,385,190 		JBrowse link
G Klc4 kinesin light chain 4 increases expression ISO Niclosamide results in increased expression of KLC4 mRNA CTD PMID:36318118 NCBI chr 9:14,337,164...14,351,075
Ensembl chr 9:14,337,534...14,351,066 		JBrowse link
G Klf15 KLF transcription factor 15 increases expression ISO Niclosamide results in increased expression of KLF15 mRNA CTD PMID:36318118 NCBI chr 4:122,965,718...122,978,403
Ensembl chr 4:122,965,807...122,978,374 		JBrowse link
G Klf9 KLF transcription factor 9 increases expression ISO Niclosamide results in increased expression of KLF9 mRNA CTD PMID:36318118 NCBI chr 1:220,700,108...220,725,110
Ensembl chr 1:220,700,108...220,725,037 		JBrowse link
G Klhdc8a kelch domain containing 8A increases expression ISO Niclosamide results in increased expression of KLHDC8A mRNA CTD PMID:36318118 NCBI chr13:43,735,702...43,744,277
Ensembl chr13:43,736,192...43,744,277 		JBrowse link
G Klhdc8b kelch domain containing 8B increases expression ISO Niclosamide results in increased expression of KLHDC8B mRNA CTD PMID:36318118 NCBI chr 8:109,141,594...109,146,584
Ensembl chr 8:109,141,594...109,146,918 		JBrowse link
G Klhl24 kelch-like family member 24 increases expression ISO Niclosamide results in increased expression of KLHL24 mRNA CTD PMID:36318118 NCBI chr11:80,843,621...80,877,649
Ensembl chr11:80,846,755...80,877,636 		JBrowse link
G Klhl30 kelch-like family member 30 increases expression ISO Niclosamide results in increased expression of KLHL30 mRNA CTD PMID:36318118 NCBI chr 9:91,942,475...91,952,756
Ensembl chr 9:91,942,504...91,952,730 		JBrowse link
G Klhl34 kelch-like family member 34 decreases expression ISO Niclosamide results in decreased expression of KLHL34 mRNA CTD PMID:36318118 NCBI chr  X:37,151,298...37,154,053
Ensembl chr  X:37,151,592...37,153,529 		JBrowse link
G Klk1c10 kallikrein 1-related peptidase C10 decreases expression
multiple interactions		 ISO Niclosamide results in decreased expression of KLK3 mRNA; Niclosamide results in decreased expression of KLK3 protein
[Niclosamide co-treated with bicalutamide] results in decreased expression of KLK3 mRNA; [Niclosamide inhibits the reaction [AR protein binds to KLK3 promoter]] which results in decreased expression of KLK3 protein; bicalutamide promotes the reaction [Niclosamide inhibits the reaction [AR protein binds to KLK3 promoter]]; enzalutamide promotes the reaction [Niclosamide results in decreased expression of KLK3 protein]; Niclosamide inhibits the reaction [AR protein alternative form binds to KLK3 promoter]; Niclosamide inhibits the reaction [AR protein alternative form results in increased expression of KLK3 mRNA]; Niclosamide inhibits the reaction [AR protein alternative form results in increased expression of KLK3 protein]; Niclosamide inhibits the reaction [AR protein binds to KLK3 promoter]; Niclosamide inhibits the reaction [Dihydrotestosterone results in increased expression of KLK3 mRNA]		 CTD PMID:24740322 PMID:25970160 PMID:28500234 NCBI chr 1:94,402,993...94,407,052
Ensembl chr 1:94,402,993...94,407,052 		JBrowse link
G Larp6 La ribonucleoprotein 6, translational regulator increases expression ISO Niclosamide results in increased expression of LARP6 mRNA CTD PMID:36318118 NCBI chr 8:61,183,744...61,205,548
Ensembl chr 8:61,184,116...61,205,535 		JBrowse link
G Lbh LBH regulator of WNT signaling pathway increases expression ISO Niclosamide results in increased expression of LBH mRNA CTD PMID:36318118 NCBI chr 6:22,569,238...22,593,056
Ensembl chr 6:22,568,834...22,593,079 		JBrowse link
G Lbx2 ladybird homeobox 2 increases expression ISO Niclosamide results in increased expression of LBX2 mRNA CTD PMID:36318118 NCBI chr 4:115,591,974...115,593,859
Ensembl chr 4:115,591,974...115,594,132 		JBrowse link
G Lcat lecithin cholesterol acyltransferase increases expression ISO Niclosamide results in increased expression of LCAT mRNA CTD PMID:28284560 NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231 		JBrowse link
G Lcmt2 leucine carboxyl methyltransferase 2 decreases expression ISO Niclosamide results in decreased expression of LCMT2 mRNA CTD PMID:36318118 NCBI chr 3:108,099,960...108,102,084
Ensembl chr 3:108,099,961...108,102,084 		JBrowse link
G Lcorl ligand dependent nuclear receptor corepressor-like increases expression ISO Niclosamide results in increased expression of LCORL mRNA CTD PMID:36318118 NCBI chr14:65,271,339...65,407,732
Ensembl chr14:65,271,135...65,404,174 		JBrowse link
G Ldha lactate dehydrogenase A increases expression
multiple interactions
decreases expression		 ISO Niclosamide results in increased expression of LDHA mRNA
Niclosamide inhibits the reaction [Oxygen deficiency results in increased expression of LDHA mRNA]
Niclosamide results in decreased expression of LDHA mRNA		 CTD PMID:22576131 PMID:36318118 NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472 		JBrowse link
G Leng9 leukocyte receptor cluster member 9 increases expression ISO Niclosamide results in increased expression of LENG9 mRNA CTD PMID:36318118 NCBI chr 1:70,039,099...70,041,559
Ensembl chr 1:70,035,791...70,044,509 		JBrowse link
G Lgals3 galectin 3 increases expression ISO Niclosamide results in increased expression of LGALS3 mRNA CTD PMID:36318118 NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025 		JBrowse link
G Lgals8 galectin 8 decreases expression ISO Niclosamide results in decreased expression of LGALS8 mRNA CTD PMID:36318118 NCBI chr17:58,024,652...58,052,764
Ensembl chr17:58,028,105...58,052,764 		JBrowse link
G Lhpp phospholysine phosphohistidine inorganic pyrophosphate phosphatase increases expression ISO Niclosamide results in increased expression of LHPP mRNA CTD PMID:36318118 NCBI chr 1:187,403,390...187,494,577
Ensembl chr 1:187,403,433...187,494,578 		JBrowse link
G Lhx6 LIM homeobox 6 increases expression ISO Niclosamide results in increased expression of LHX6 mRNA CTD PMID:36318118 NCBI chr 3:19,432,439...19,456,268
Ensembl chr 3:19,433,494...19,456,061 		JBrowse link
G Lingo1 leucine rich repeat and Ig domain containing 1 increases expression ISO Niclosamide results in increased expression of LINGO1 mRNA CTD PMID:36318118 NCBI chr 8:57,011,272...57,193,496
Ensembl chr 8:57,010,007...57,196,544 		JBrowse link
G Lipg lipase G, endothelial type decreases expression ISO Niclosamide results in decreased expression of LIPG mRNA CTD PMID:36318118 NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260 		JBrowse link
G Lix1 limb and CNS expressed 1 decreases expression ISO Niclosamide results in decreased expression of LIX1 mRNA CTD PMID:36318118 NCBI chr 1:58,128,961...58,187,554
Ensembl chr 1:58,128,961...58,185,964 		JBrowse link
G Lmtk3 lemur tyrosine kinase 3 increases expression ISO Niclosamide results in increased expression of LMTK3 mRNA CTD PMID:36318118 NCBI chr 1:96,261,058...96,280,362
Ensembl chr 1:96,260,977...96,280,672 		JBrowse link
G Lonrf1 LON peptidase N-terminal domain and ring finger 1 increases expression ISO Niclosamide results in increased expression of LONRF1 mRNA CTD PMID:36318118 NCBI chr16:55,984,572...56,015,156
Ensembl chr16:55,984,463...56,015,156 		JBrowse link
G Loxl3 lysyl oxidase-like 3 increases expression ISO Niclosamide results in increased expression of LOXL3 mRNA CTD PMID:36318118 NCBI chr 4:115,540,640...115,556,958
Ensembl chr 4:115,540,685...115,557,466 		JBrowse link
G Lpin3 lipin 3 increases expression ISO Niclosamide results in increased expression of LPIN3 mRNA CTD PMID:36318118 NCBI chr 3:149,533,719...149,558,494
Ensembl chr 3:149,534,051...149,558,327 		JBrowse link
G Lrp1 LDL receptor related protein 1 increases expression ISO Niclosamide results in increased expression of LRP1 mRNA CTD PMID:36318118 NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910 		JBrowse link
G Lrp10 LDL receptor related protein 10 increases expression ISO Niclosamide results in increased expression of LRP10 mRNA CTD PMID:36318118 NCBI chr15:27,921,335...27,927,507
Ensembl chr15:27,920,259...27,927,505 		JBrowse link
G Lrp5 LDL receptor related protein 5 multiple interactions EXP Niclosamide inhibits the reaction [Thioacetamide results in increased expression of LRP5 mRNA]; Poloxamer promotes the reaction [Niclosamide inhibits the reaction [Thioacetamide results in increased expression of LRP5 mRNA]] CTD PMID:32961231 NCBI chr 1:200,814,247...200,917,581
Ensembl chr 1:200,814,250...200,917,581 		JBrowse link
G Lrp6 LDL receptor related protein 6 decreases expression
multiple interactions		 ISO
EXP		 Niclosamide analog results in decreased expression of LRP6 protein; Niclosamide results in decreased expression of LRP6 protein
Niclosamide results in decreased expression of and results in decreased phosphorylation of LRP6 protein
Niclosamide inhibits the reaction [Thioacetamide results in increased expression of LRP6 mRNA]; Poloxamer promotes the reaction [Niclosamide inhibits the reaction [Thioacetamide results in increased expression of LRP6 mRNA]]		 CTD PMID:24552774 PMID:24736023 PMID:28284560 PMID:32961231 NCBI chr 4:167,269,856...167,400,364
Ensembl chr 4:167,270,353...167,400,497 		JBrowse link
G Lrrc2 leucine rich repeat containing 2 increases expression ISO Niclosamide results in increased expression of LRRC2 mRNA CTD PMID:36318118 NCBI chr 8:110,936,119...110,969,189
Ensembl chr 8:110,938,165...110,969,185 		JBrowse link
G Lrrc55 leucine rich repeat containing 55 decreases expression ISO Niclosamide results in decreased expression of LRRC55 mRNA CTD PMID:36318118 NCBI chr 3:70,269,908...70,280,651
Ensembl chr 3:70,265,936...70,278,639 		JBrowse link
G Lrrc73 leucine rich repeat containing 73 increases expression ISO Niclosamide results in increased expression of LRRC73 mRNA CTD PMID:36318118 NCBI chr 9:14,726,157...14,730,144
Ensembl chr 9:14,726,158...14,729,158 		JBrowse link
G Lrrc75b leucine rich repeat containing 75B increases expression ISO Niclosamide results in increased expression of LRRC75B mRNA CTD PMID:36318118 NCBI chr20:13,100,302...13,106,503
Ensembl chr20:13,100,302...13,106,503 		JBrowse link
G Lsp1 lymphocyte-specific protein 1 decreases expression ISO Niclosamide results in decreased expression of LSP1 mRNA CTD PMID:36318118 NCBI chr 1:197,614,677...197,648,414
Ensembl chr 1:197,614,687...197,648,416 		JBrowse link
G Ltbp4 latent transforming growth factor beta binding protein 4 increases expression ISO Niclosamide results in increased expression of LTBP4 mRNA CTD PMID:36318118 NCBI chr 1:82,600,136...82,634,346
Ensembl chr 1:82,600,136...82,632,178 		JBrowse link
G Ly6g5b lymphocyte antigen 6 family member G5B decreases expression ISO Niclosamide results in decreased expression of LY6G5B mRNA CTD PMID:36318118 NCBI chr20:3,705,464...3,707,830
Ensembl chr20:3,706,124...3,707,133 		JBrowse link
G Lyrm9 LYR motif containing 9 increases expression ISO Niclosamide results in increased expression of LYRM9 mRNA CTD PMID:36318118 NCBI chr10:63,725,718...63,739,772
Ensembl chr10:63,725,743...63,739,772 		JBrowse link
G Macc1 MET transcriptional regulator MACC1 multiple interactions ISO Niclosamide inhibits the reaction [MACC1 protein results in increased expression of S100A4 protein] CTD PMID:36008464 NCBI chr 6:140,352,690...140,430,255
Ensembl chr 6:140,352,755...140,430,255 		JBrowse link
G Mad2l1 mitotic arrest deficient 2 like 1 decreases expression ISO Niclosamide results in decreased expression of MAD2L1 mRNA CTD PMID:28284560 NCBI chr 4:95,906,692...95,918,885
Ensembl chr 4:95,906,817...95,913,470 		JBrowse link
G Magix MAGI family member, X-linked increases expression ISO Niclosamide results in increased expression of MAGIX mRNA CTD PMID:36318118 NCBI chr  X:14,824,114...14,832,466
Ensembl chr  X:14,824,188...14,831,045 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases expression ISO Niclosamide results in increased expression of MAP1LC3B protein modified form CTD PMID:30258081 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases phosphorylation
multiple interactions		 ISO Niclosamide results in decreased phosphorylation of MAPK1 protein
Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of MAPK1 protein]; Niclosamide inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]		 CTD PMID:24561310 PMID:26116531 PMID:28426875 PMID:28824321 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
decreases phosphorylation		 ISO Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of MAPK3 protein]; Niclosamide inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein]
Niclosamide results in decreased phosphorylation of MAPK3 protein		 CTD PMID:24561310 PMID:26116531 PMID:28426875 PMID:28824321 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of MAPK8 protein] CTD PMID:28824321 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions ISO Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of MAPK9 protein] CTD PMID:28824321 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178 		JBrowse link
G Mapt microtubule-associated protein tau increases expression ISO Niclosamide results in increased expression of MAPT mRNA CTD PMID:36318118 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129 		JBrowse link
G Masp1 MBL associated serine protease 1 increases expression ISO Niclosamide results in increased expression of MASP1 mRNA CTD PMID:36318118 NCBI chr11:77,334,794...77,405,271
Ensembl chr11:77,334,859...77,402,974 		JBrowse link
G MAST1 microtubule associated serine/threonine kinase 1 increases expression ISO Niclosamide results in increased expression of MAST1 mRNA CTD PMID:36318118 NCBI chr19:23,216,418...23,244,224
Ensembl chr19:23,207,991...23,244,235 		JBrowse link
G Mat2a methionine adenosyltransferase 2A decreases expression ISO Niclosamide results in decreased expression of MAT2A mRNA CTD PMID:36318118 NCBI chr 4:104,489,877...104,495,447
Ensembl chr 4:104,488,466...104,495,493 		JBrowse link
G Matn1 matrilin 1 increases expression ISO Niclosamide results in increased expression of MATN1 mRNA CTD PMID:36318118 NCBI chr 5:143,117,198...143,127,140
Ensembl chr 5:143,117,504...143,127,059 		JBrowse link
G Mboat7 membrane bound O-acyltransferase domain containing 7 increases expression ISO Niclosamide results in increased expression of MBOAT7 mRNA CTD PMID:36318118 NCBI chr 1:65,525,206...65,539,538
Ensembl chr 1:65,525,213...65,539,538 		JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member decreases expression ISO Niclosamide results in decreased expression of MCL1 protein CTD PMID:20215516 PMID:26116531 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303 		JBrowse link
G Mcm10 minichromosome maintenance 10 replication initiation factor decreases expression ISO Niclosamide results in decreased expression of MCM10 mRNA CTD PMID:36318118 NCBI chr17:73,263,788...73,288,346
Ensembl chr17:73,266,095...73,287,364 		JBrowse link
G Mcm2 minichromosome maintenance complex component 2 decreases expression ISO Niclosamide results in decreased expression of MCM2 mRNA; Niclosamide results in decreased expression of MCM2 protein CTD PMID:28284560 PMID:29031202 NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847 		JBrowse link
G Mcm5 minichromosome maintenance complex component 5 decreases expression ISO Niclosamide results in decreased expression of MCM5 mRNA CTD PMID:36318118 NCBI chr19:13,483,030...13,504,389
Ensembl chr19:13,483,066...13,504,389 		JBrowse link
G Mcm6 minichromosome maintenance complex component 6 decreases expression ISO Niclosamide results in decreased expression of MCM6 mRNA CTD PMID:36318118 NCBI chr13:39,826,745...39,851,937
Ensembl chr13:39,826,763...39,851,960 		JBrowse link
G Mcm7 minichromosome maintenance complex component 7 decreases expression ISO Niclosamide results in decreased expression of MCM7 protein CTD PMID:29031202 NCBI chr12:17,042,207...17,049,470
Ensembl chr12:17,042,212...17,050,063 		JBrowse link
G Me3 malic enzyme 3 decreases expression ISO Niclosamide results in decreased expression of ME3 mRNA CTD PMID:36318118 NCBI chr 1:143,534,024...143,735,551
Ensembl chr 1:143,534,139...143,733,132 		JBrowse link
G Med31 mediator complex subunit 31 decreases expression ISO Niclosamide results in decreased expression of MED31 mRNA CTD PMID:36318118 NCBI chr10:56,836,944...56,840,326
Ensembl chr10:56,836,944...56,840,326 		JBrowse link
G Mef2d myocyte enhancer factor 2D increases expression ISO Niclosamide results in increased expression of MEF2D mRNA CTD PMID:36318118 NCBI chr 2:173,606,054...173,635,620
Ensembl chr 2:173,606,490...173,634,457 		JBrowse link
G Meis3 Meis homeobox 3 increases expression ISO Niclosamide results in increased expression of MEIS3 mRNA CTD PMID:36318118 NCBI chr 1:76,861,267...76,872,691
Ensembl chr 1:76,861,924...76,872,691 		JBrowse link
G Mesp1 mesoderm posterior bHLH transcription factor 1 increases expression ISO Niclosamide results in increased expression of MESP1 mRNA CTD PMID:36318118 NCBI chr 1:133,738,357...133,739,875
Ensembl chr 1:133,738,357...133,739,875 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase decreases expression EXP Niclosamide results in decreased expression of MET mRNA CTD PMID:27338550 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876 		JBrowse link
G Metrnl meteorin-like, glial cell differentiation regulator increases expression ISO Niclosamide results in increased expression of METRNL mRNA CTD PMID:36318118 NCBI chr10:106,963,880...106,977,875
Ensembl chr10:106,963,880...106,977,869 		JBrowse link
G Mgll monoglyceride lipase increases expression ISO Niclosamide results in increased expression of MGLL mRNA CTD PMID:36318118 NCBI chr 4:121,192,186...121,294,187
Ensembl chr 4:121,192,195...121,294,179 		JBrowse link
G Minar2 membrane integral NOTCH2 associated receptor 2 decreases expression ISO Niclosamide results in decreased expression of MINAR2 mRNA CTD PMID:36318118 NCBI chr18:52,539,714...52,554,465
Ensembl chr18:52,539,917...52,554,461 		JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression ISO Niclosamide results in decreased expression of MKI67 mRNA; Niclosamide results in decreased expression of MKI67 protein CTD PMID:28284560 PMID:35115509 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762 		JBrowse link
G Mknk2 MAPK interacting serine/threonine kinase 2 increases expression ISO Niclosamide results in increased expression of MKNK2 mRNA CTD PMID:36318118 NCBI chr 7:9,039,771...9,050,832
Ensembl chr 7:9,039,728...9,050,827 		JBrowse link
G Mme membrane metallo-endopeptidase decreases expression ISO Niclosamide results in decreased expression of MME mRNA; Niclosamide results in decreased expression of MME protein CTD PMID:29480568 NCBI chr 2:147,686,913...147,803,808
Ensembl chr 2:147,722,086...147,803,792 		JBrowse link
G Mmp11 matrix metallopeptidase 11 increases expression ISO Niclosamide results in increased expression of MMP11 mRNA CTD PMID:36318118 NCBI chr20:12,730,846...12,739,629
Ensembl chr20:12,730,836...12,739,628 		JBrowse link
G Mmp15 matrix metallopeptidase 15 increases expression ISO Niclosamide results in increased expression of MMP15 mRNA CTD PMID:36318118 NCBI chr19:9,663,449...9,684,943
Ensembl chr19:9,663,449...9,684,943 		JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression ISO Niclosamide results in decreased expression of MMP2 mRNA; Niclosamide results in decreased expression of MMP2 protein CTD PMID:29251334 PMID:30143678 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp7 matrix metallopeptidase 7 multiple interactions
decreases expression		 EXP
ISO		 Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of MMP7 mRNA]
Niclosamide results in decreased expression of MMP7 mRNA
Niclosamide inhibits the reaction [Doxorubicin results in increased expression of MMP7 mRNA]		 CTD PMID:27338550 PMID:28318631 NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902 		JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression
multiple interactions		 ISO Niclosamide results in decreased expression of MMP9 mRNA; Niclosamide results in decreased expression of MMP9 protein
Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of MMP9 mRNA]		 CTD PMID:28824321 PMID:29480568 PMID:30143678 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mrc2 mannose receptor, C type 2 increases expression ISO Niclosamide results in increased expression of MRC2 mRNA CTD PMID:36318118 NCBI chr10:90,261,986...90,323,187
Ensembl chr10:90,261,394...90,322,856 		JBrowse link
G Mrm2 mitochondrial rRNA methyltransferase 2 decreases expression ISO Niclosamide results in decreased expression of MRM2 mRNA CTD PMID:36318118 NCBI chr12:14,309,556...14,314,759
Ensembl chr12:14,251,941...14,314,118 		JBrowse link
G Mrpl30 mitochondrial ribosomal protein L30 decreases expression ISO Niclosamide results in decreased expression of MRPL30 mRNA CTD PMID:36318118 NCBI chr 9:40,125,352...40,136,189
Ensembl chr 9:40,125,430...40,137,257 		JBrowse link
G Msantd7 Myb/SANT DNA binding domain containing 7 decreases expression ISO Niclosamide results in decreased expression of MSANTD7 mRNA CTD PMID:36318118 NCBI chr17:74,728,927...74,735,527
Ensembl chr17:74,728,811...74,736,094 		JBrowse link
G Mt1-ps3 metallothionein 1, pseudogene 3 increases expression ISO Niclosamide results in increased expression of MT1E mRNA CTD PMID:28284560 NCBI chr17:74,786,652...74,787,040
Ensembl chr17:74,786,654...74,787,135 		JBrowse link
G Mt2A metallothionein 2A increases expression ISO Niclosamide results in increased expression of MT2A mRNA CTD PMID:28284560 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784 		JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases phosphorylation
increases expression
multiple interactions		 ISO Niclosamide analog results in decreased phosphorylation of MTOR protein; Niclosamide results in decreased phosphorylation of MTOR protein
Niclosamide results in increased expression of MTOR mRNA
Niclosamide inhibits the reaction [[Lapatinib results in decreased susceptibility to Lapatinib] which results in increased phosphorylation of MTOR protein]; Niclosamide inhibits the reaction [MTOR protein results in increased phosphorylation of EIF4EBP1 protein]		 CTD PMID:19771169 PMID:26643609 PMID:26703449 PMID:28284560 PMID:29843133 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Mvp major vault protein increases expression ISO Niclosamide results in increased expression of MVP mRNA CTD PMID:36318118 NCBI chr 1:181,594,734...181,622,336
Ensembl chr 1:181,594,734...181,622,380 		JBrowse link
G Mxi1 MAX interactor 1, dimerization protein increases expression ISO Niclosamide results in increased expression of MXI1 mRNA CTD PMID:36318118 NCBI chr 1:252,323,915...252,383,682
Ensembl chr 1:252,323,303...252,383,681 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions
decreases expression		 EXP
ISO		 Niclosamide inhibits the reaction [GCG protein results in increased expression of MYC mRNA]
[Niclosamide binds to Polyethyleneimine] which results in increased expression of MYC mRNA; [Niclosamide co-treated with bicalutamide] results in decreased expression of MYC mRNA; [Niclosamide co-treated with bicalutamide] results in decreased expression of MYC protein; enzalutamide promotes the reaction [Niclosamide results in decreased expression of MYC protein]; Niclosamide inhibits the reaction [bicalutamide results in increased expression of MYC protein]; Niclosamide inhibits the reaction [IL6 protein results in increased expression of MYC protein]; Niclosamide inhibits the reaction [TNF protein results in increased expression of MYC mRNA]
Niclosamide results in decreased expression of MYC mRNA; Niclosamide results in decreased expression of MYC protein		 CTD PMID:19160421 PMID:20215516 PMID:22576131 PMID:25970160 PMID:25988281 More... NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Mycl MYCL proto-oncogene, bHLH transcription factor increases expression ISO Niclosamide results in increased expression of MYCL mRNA CTD PMID:36318118 NCBI chr 5:135,274,713...135,281,584
Ensembl chr 5:135,274,748...135,281,582 		JBrowse link
G Mycn MYCN proto-oncogene, bHLH transcription factor decreases expression ISO Niclosamide results in decreased expression of MYCN mRNA; Niclosamide results in decreased expression of MYCN protein CTD PMID:36318118 NCBI chr 6:35,717,764...35,723,590
Ensembl chr 6:35,717,764...35,723,590 		JBrowse link
G Myo18b myosin XVIIIb increases expression ISO Niclosamide results in increased expression of MYO18B mRNA CTD PMID:36318118 NCBI chr12:43,747,003...43,953,694
Ensembl chr12:43,747,010...43,953,695 		JBrowse link
G Myom3 myomesin 3 increases expression ISO Niclosamide results in increased expression of MYOM3 mRNA CTD PMID:36318118 NCBI chr 5:147,992,737...148,043,282
Ensembl chr 5:147,992,737...148,043,274 		JBrowse link
G Myrf myelin regulatory factor increases expression ISO Niclosamide results in increased expression of MYRF mRNA CTD PMID:36318118 NCBI chr 1:206,854,175...206,886,276
Ensembl chr 1:206,854,175...206,886,157 		JBrowse link
G N4bp2l1 NEDD4 binding protein 2-like 1 increases expression ISO Niclosamide results in increased expression of N4BP2L1 mRNA CTD PMID:36318118 NCBI chr12:102,572...128,352
Ensembl chr12:102,573...127,257 		JBrowse link
G Naa80 N(alpha)-acetyltransferase 80, NatH catalytic subunit increases expression ISO Niclosamide results in increased expression of NAA80 mRNA CTD PMID:36318118 NCBI chr 8:108,254,314...108,257,564
Ensembl chr 8:108,253,302...108,257,563 		JBrowse link
G Nat1 N-acetyltransferase 1 decreases expression ISO Niclosamide results in decreased expression of NAT1 mRNA CTD PMID:36318118 NCBI chr16:22,218,217...22,238,516
Ensembl chr16:22,208,194...22,238,520 		JBrowse link
G Natd1 N-acetyltransferase domain containing 1 increases expression ISO Niclosamide results in increased expression of NATD1 mRNA CTD PMID:36318118 NCBI chr10:45,580,154...45,590,333 JBrowse link
G Nbr1 NBR1, autophagy cargo receptor increases expression ISO Niclosamide results in increased expression of NBR1 mRNA CTD PMID:36318118 NCBI chr10:86,477,775...86,506,418
Ensembl chr10:86,478,290...86,506,412 		JBrowse link
G Ncoa5 nuclear receptor coactivator 5 decreases expression ISO Niclosamide results in decreased expression of NCOA5 mRNA CTD PMID:36318118 NCBI chr 3:153,736,420...153,769,838
Ensembl chr 3:153,736,420...153,769,553 		JBrowse link
G Ndor1 NADPH dependent diflavin oxidoreductase 1 decreases expression ISO Niclosamide results in decreased expression of NDOR1 mRNA CTD PMID:36318118 NCBI chr 3:8,062,629...8,070,873
Ensembl chr 3:8,062,630...8,070,860 		JBrowse link
G Ndrg1 N-myc downstream regulated 1 increases expression ISO Niclosamide results in increased expression of NDRG1 mRNA CTD PMID:36318118 NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880 		JBrowse link
G Ndufa10 NADH:ubiquinone oxidoreductase subunit A10 decreases expression ISO Niclosamide results in decreased expression of NDUFA10 mRNA CTD PMID:22576131 NCBI chr 9:93,007,034...93,041,825
Ensembl chr 9:93,007,042...93,042,560 		JBrowse link
G Ndufa4l2 NDUFA4, mitochondrial complex associated like 2 increases expression ISO Niclosamide results in increased expression of NDUFA4L2 mRNA CTD PMID:22576131 PMID:36318118 NCBI chr 7:63,351,021...63,359,010
Ensembl chr 7:63,356,883...63,359,010 		JBrowse link
G Ndufa7 NADH:ubiquinone oxidoreductase subunit A7 decreases expression ISO Niclosamide results in decreased expression of NDUFA7 mRNA CTD PMID:22576131 NCBI chr 7:14,609,283...14,622,064
Ensembl chr 7:14,609,146...14,631,976 		JBrowse link
G Ndufa8 NADH:ubiquinone oxidoreductase subunit A8 decreases expression ISO Niclosamide results in decreased expression of NDUFA8 mRNA CTD PMID:22576131 NCBI chr 3:19,386,062...19,402,090
Ensembl chr 3:19,386,065...19,402,071 		JBrowse link
G Ndufb10 NADH:ubiquinone oxidoreductase subunit B10 decreases expression ISO Niclosamide results in decreased expression of NDUFB10 mRNA CTD PMID:22576131 NCBI chr10:13,749,273...13,751,434
Ensembl chr10:13,749,275...13,751,442 		JBrowse link
G Ndufb6 NADH:ubiquinone oxidoreductase subunit B6 decreases expression ISO Niclosamide results in decreased expression of NDUFB6 mRNA CTD PMID:22576131 NCBI chr 5:55,400,543...55,410,110
Ensembl chr 5:55,400,543...55,410,181 		JBrowse link
G Ndufc1 NADH:ubiquinone oxidoreductase subunit C1 increases expression ISO Niclosamide results in increased expression of NDUFC1 mRNA CTD PMID:22576131 NCBI chr 2:135,447,067...135,450,950
Ensembl chr 2:135,447,119...135,450,874 		JBrowse link
G Ndufs2 NADH:ubiquinone oxidoreductase core subunit S2 decreases expression ISO Niclosamide results in decreased expression of NDUFS2 mRNA CTD PMID:22576131 NCBI chr13:83,654,402...83,671,474
Ensembl chr13:83,654,406...83,671,420 		JBrowse link
G Ndufs3 NADH:ubiquinone oxidoreductase core subunit S3 decreases expression ISO Niclosamide results in decreased expression of NDUFS3 mRNA CTD PMID:22576131 NCBI chr 3:76,876,646...76,883,824
Ensembl chr 3:76,876,646...76,883,824 		JBrowse link
G Ndufs7 NADH:ubiquinone oxidoreductase core subunit S7 decreases expression ISO Niclosamide results in decreased expression of NDUFS7 mRNA CTD PMID:22576131 NCBI chr 7:9,452,556...9,460,135
Ensembl chr 7:9,450,392...9,460,195 		JBrowse link
G Ndufs8 NADH:ubiquinone oxidoreductase core subunit S8 decreases expression ISO Niclosamide results in decreased expression of NDUFS8 mRNA CTD PMID:22576131 NCBI chr 1:201,140,585...201,144,573
Ensembl chr 1:201,140,585...201,144,511 		JBrowse link
G Ndufv3 NADH:ubiquinone oxidoreductase subunit V3 increases expression ISO Niclosamide results in increased expression of NDUFV3 mRNA CTD PMID:22576131 NCBI chr20:9,612,462...9,621,622
Ensembl chr20:9,612,431...9,623,074
Ensembl chr13:9,612,431...9,623,074 		JBrowse link
G Nectin3 nectin cell adhesion molecule 3 decreases expression ISO Niclosamide results in decreased expression of NECTIN3 mRNA CTD PMID:36318118 NCBI chr11:54,362,712...54,469,351
Ensembl chr11:54,364,487...54,462,519 		JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 multiple interactions ISO Niclosamide inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 mRNA]; Niclosamide inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 protein]
Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of and affects the localization of NFATC1 protein]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of NFATC1 mRNA]		 CTD PMID:26792726 PMID:28824321 NCBI chr18:74,046,422...74,156,041
Ensembl chr18:74,046,904...74,156,028 		JBrowse link
G Nfatc2ip nuclear factor of activated T-cells 2 interacting protein decreases expression ISO Niclosamide results in decreased expression of NFATC2IP mRNA CTD PMID:36318118 NCBI chr 1:180,954,834...180,971,847
Ensembl chr 1:180,955,043...180,971,747 		JBrowse link
G Nfix nuclear factor I X increases expression ISO Niclosamide results in increased expression of NFIX mRNA CTD PMID:36318118 NCBI chr19:23,355,388...23,450,360
Ensembl chr19:23,355,498...23,448,265 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 affects localization ISO Niclosamide affects the localization of NFKB1 protein CTD PMID:26116531 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nfkb2 nuclear factor kappa B subunit 2 increases expression ISO Niclosamide results in increased expression of NFKB2 mRNA CTD PMID:36318118 NCBI chr 1:245,164,586...245,173,225
Ensembl chr 1:245,165,950...245,173,213 		JBrowse link
G Nfkbia NFKB inhibitor alpha decreases phosphorylation
multiple interactions		 ISO Niclosamide results in decreased phosphorylation of NFKBIA protein
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Niclosamide inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of NFKBIA protein]]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of NFKBIA protein]; Niclosamide inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of NFKBIA protein]
Niclosamide inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]; Niclosamide inhibits the reaction [TNF protein results in increased phosphorylation of NFKBIA protein]		 CTD PMID:20215516 PMID:26116531 PMID:27492973 PMID:28824321 PMID:33524445 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nfkbil1 NFKB inhibitor like 1 increases expression ISO Niclosamide results in increased expression of NFKBIL1 mRNA CTD PMID:36318118 NCBI chr20:3,589,974...3,608,348
Ensembl chr20:3,590,642...3,605,616 		JBrowse link
G Nkd1 NKD inhibitor of WNT signaling pathway 1 multiple interactions
increases expression		 ISO Niclosamide inhibits the reaction [Lithium Chloride results in increased expression of NKD1 mRNA]
Niclosamide results in increased expression of NKD1 mRNA		 CTD PMID:22576131 PMID:24534281 NCBI chr19:18,476,344...18,549,380
Ensembl chr19:18,476,344...18,549,380 		JBrowse link
G Nkx3-1 NK3 homeobox 1 multiple interactions
decreases expression		 ISO [Niclosamide co-treated with bicalutamide] results in decreased expression of NKX3-1 mRNA
Niclosamide results in decreased expression of NKX3-1 mRNA		 CTD PMID:28500234 NCBI chr15:44,473,851...44,476,443
Ensembl chr15:44,473,851...44,476,441 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO Niclosamide inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of NLRP3 protein] CTD PMID:33524445 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
G Nmrk1 nicotinamide riboside kinase 1 increases expression ISO Niclosamide results in increased expression of NMRK1 mRNA CTD PMID:36318118 NCBI chr 1:216,049,350...216,076,792
Ensembl chr 1:216,049,437...216,076,791 		JBrowse link
G Nnat neuronatin decreases expression ISO Niclosamide results in decreased expression of NNAT mRNA CTD PMID:36318118 NCBI chr 3:146,225,941...146,228,868
Ensembl chr 3:146,226,407...146,228,834 		JBrowse link
G Nostrin nitric oxide synthase trafficking decreases expression ISO Niclosamide results in decreased expression of NOSTRIN mRNA CTD PMID:36318118 NCBI chr 3:53,904,746...53,970,995
Ensembl chr 3:53,904,827...53,970,988 		JBrowse link
G Notch1 notch receptor 1 decreases activity
multiple interactions		 ISO
EXP		 Niclosamide results in decreased activity of NOTCH1 protein
Niclosamide inhibits the reaction [Thioacetamide results in increased expression of NOTCH1 mRNA]; Poloxamer promotes the reaction [Niclosamide inhibits the reaction [Thioacetamide results in increased expression of NOTCH1 mRNA]]		 CTD PMID:19160421 PMID:32961231 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Notum NOTUM, palmitoleoyl-protein carboxylesterase increases expression ISO Niclosamide results in increased expression of NOTUM mRNA CTD PMID:36318118 NCBI chr10:105,933,245...105,940,327
Ensembl chr10:105,933,249...105,940,315 		JBrowse link
G Nova2 NOVA alternative splicing regulator 2 increases expression ISO Niclosamide results in increased expression of NOVA2 mRNA CTD PMID:36318118 NCBI chr 1:78,572,253...78,613,703
Ensembl chr 1:78,572,279...78,608,021 		JBrowse link
G Nox1 NADPH oxidase 1 decreases expression ISO Niclosamide results in decreased expression of NOX1 mRNA CTD PMID:36318118 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236 		JBrowse link
G Npas4 neuronal PAS domain protein 4 increases expression ISO Niclosamide results in increased expression of NPAS4 mRNA CTD PMID:36318118 NCBI chr 1:202,281,260...202,298,681
Ensembl chr 1:202,281,958...202,286,724 		JBrowse link
G Npr1 natriuretic peptide receptor 1 increases expression ISO Niclosamide results in increased expression of NPR1 mRNA CTD PMID:36318118 NCBI chr 2:175,934,181...175,950,118
Ensembl chr 2:175,934,181...175,949,505 		JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 increases expression ISO Niclosamide results in increased expression of NR1D1 mRNA CTD PMID:36318118 NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705 		JBrowse link
G Nr1d2 nuclear receptor subfamily 1, group D, member 2 increases expression ISO Niclosamide results in increased expression of NR1D2 mRNA CTD PMID:36318118 NCBI chr15:7,524,257...7,550,553
Ensembl chr15:7,524,257...7,550,553 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions ISO Niclosamide binds to and results in increased activity of NR1I3 protein alternative form CTD PMID:31312845 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906 		JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 increases expression ISO Niclosamide results in increased expression of NR4A1 mRNA CTD PMID:36318118 NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297 		JBrowse link
G Nrxn2 neurexin 2 increases expression ISO Niclosamide results in increased expression of NRXN2 mRNA CTD PMID:36318118 NCBI chr 1:203,726,420...203,842,301
Ensembl chr 1:203,735,753...203,842,297 		JBrowse link
G Nt5m 5',3'-nucleotidase, mitochondrial increases expression ISO Niclosamide results in increased expression of NT5M mRNA CTD PMID:36318118 NCBI chr10:44,652,845...44,680,549
Ensembl chr10:44,652,975...44,679,150 		JBrowse link
G Ntng2 netrin G2 increases expression ISO Niclosamide results in increased expression of NTNG2 mRNA CTD PMID:36318118 NCBI chr 3:12,492,574...12,551,104
Ensembl chr 3:12,492,639...12,545,890 		JBrowse link
G Nudt18 nudix hydrolase 18 increases expression ISO Niclosamide results in increased expression of NUDT18 mRNA CTD PMID:36318118 NCBI chr15:45,650,597...45,653,985
Ensembl chr15:45,650,664...45,653,963 		JBrowse link
G Nupr2 nuclear protein 2, transcriptional regulator increases expression ISO Niclosamide results in increased expression of NUPR2 mRNA CTD PMID:36318118 NCBI chr12:26,800,123...26,803,228
Ensembl chr12:26,799,800...26,803,304 		JBrowse link
G Nxph1 neurexophilin 1 decreases expression ISO Niclosamide results in decreased expression of NXPH1 mRNA CTD PMID:36318118 NCBI chr 4:36,998,068...37,311,135
Ensembl chr 4:36,997,669...37,311,132 		JBrowse link
G Nxph2 neurexophilin 2 decreases expression ISO Niclosamide results in decreased expression of NXPH2 mRNA CTD PMID:36318118 NCBI chr 3:5,986,175...5,988,525
Ensembl chr 3:5,756,621...5,987,008 		JBrowse link
G Nxph4 neurexophilin 4 increases expression ISO Niclosamide results in increased expression of NXPH4 mRNA CTD PMID:36318118 NCBI chr 7:63,367,758...63,376,579
Ensembl chr 7:63,367,761...63,376,579 		JBrowse link
G Nyap1 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 1 increases expression ISO Niclosamide results in increased expression of NYAP1 mRNA CTD PMID:36318118 NCBI chr12:18,956,192...18,967,624
Ensembl chr12:18,956,268...18,967,543 		JBrowse link
G Oas1a 2'-5' oligoadenylate synthetase 1A decreases expression ISO Niclosamide results in decreased expression of OAS1 mRNA CTD PMID:36318118 NCBI chr12:35,669,798...35,680,505
Ensembl chr12:35,669,801...35,680,517 		JBrowse link
G Oaz3 ornithine decarboxylase antizyme 3 increases expression ISO Niclosamide results in increased expression of OAZ3 mRNA CTD PMID:36318118 NCBI chr 2:182,073,212...182,076,147
Ensembl chr 2:182,073,215...182,082,399 		JBrowse link
G Oca2 OCA2 melanosomal transmembrane protein increases expression ISO Niclosamide results in increased expression of OCA2 mRNA CTD PMID:36318118 NCBI chr 1:107,116,278...107,446,093
Ensembl chr 1:107,116,278...107,446,074 		JBrowse link
G Ocstamp osteoclast stimulatory transmembrane protein multiple interactions ISO Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of OCSTAMP mRNA] CTD PMID:28824321 NCBI chr 3:154,131,113...154,141,611
Ensembl chr 3:154,132,328...154,136,991 		JBrowse link
G Olr765 olfactory receptor 765 decreases expression ISO Niclosamide results in decreased expression of OR4F17 mRNA CTD PMID:36318118 NCBI chr 3:98,118,744...98,121,011
Ensembl chr 3:98,097,957...98,101,421 		JBrowse link
G Opcml opioid binding protein/cell adhesion molecule-like increases expression ISO Niclosamide results in increased expression of OPCML mRNA CTD PMID:36318118 NCBI chr 8:26,788,988...27,304,551
Ensembl chr 8:26,192,841...27,300,620 		JBrowse link
G Opn3 opsin 3 increases expression ISO Niclosamide results in increased expression of OPN3 mRNA CTD PMID:36318118 NCBI chr13:87,589,333...87,619,847
Ensembl chr13:87,589,333...87,619,847 		JBrowse link
G Orai3 ORAI calcium release-activated calcium modulator 3 increases expression ISO Niclosamide results in increased expression of ORAI3 mRNA CTD PMID:36318118 NCBI chr 1:182,381,196...182,386,055
Ensembl chr 1:182,344,293...182,386,052 		JBrowse link
G Orc1 origin recognition complex, subunit 1 decreases expression ISO Niclosamide results in decreased expression of ORC1 mRNA CTD PMID:28284560 PMID:36318118 NCBI chr 5:123,324,273...123,348,375
Ensembl chr 5:123,324,315...123,348,375 		JBrowse link
G Oscar osteoclast associated Ig-like receptor multiple interactions ISO Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of OSCAR mRNA]
Niclosamide inhibits the reaction [TNFSF11 protein results in increased expression of OSCAR mRNA]		 CTD PMID:26792726 PMID:28824321 NCBI chr 1:65,607,214...65,615,395
Ensembl chr 1:65,607,410...65,613,758 		JBrowse link
G Otud1 OTU deubiquitinase 1 increases expression ISO Niclosamide results in increased expression of OTUD1 mRNA CTD PMID:36318118 NCBI chr17:82,259,920...82,262,770
Ensembl chr17:82,259,840...82,262,995 		JBrowse link
G Otulinl OTU deubiquitinase with linear linkage specificity like decreases expression ISO Niclosamide results in decreased expression of OTULINL mRNA CTD PMID:36318118 NCBI chr 2:78,405,994...78,433,860
Ensembl chr 2:78,408,593...78,433,838 		JBrowse link
G P2ry6 pyrimidinergic receptor P2Y6 decreases expression ISO Niclosamide results in decreased expression of P2RY6 mRNA CTD PMID:36318118 NCBI chr 1:155,295,110...155,330,610
Ensembl chr 1:155,295,111...155,330,808 		JBrowse link
G Paip2b poly(A) binding protein interacting protein 2B increases expression ISO Niclosamide results in increased expression of PAIP2B mRNA CTD PMID:36318118 NCBI chr 4:116,292,001...116,323,387
Ensembl chr 4:116,292,020...116,323,379 		JBrowse link
G Palm paralemmin increases expression ISO Niclosamide results in increased expression of PALM mRNA CTD PMID:36318118 NCBI chr 7:9,886,634...9,912,389
Ensembl chr 7:9,886,643...9,912,555 		JBrowse link
G Pard3b par-3 family cell polarity regulator beta increases expression ISO Niclosamide results in increased expression of PARD3B mRNA CTD PMID:36318118 NCBI chr 9:63,038,435...64,067,178
Ensembl chr 9:63,038,436...64,068,053 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases cleavage
increases expression
decreases expression		 ISO [TP53 protein mutant form results in increased susceptibility to Niclosamide] which results in increased cleavage of PARP1 protein
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Niclosamide results in increased cleavage of PARP1 protein]; bicalutamide promotes the reaction [Niclosamide results in increased expression of PARP1 protein modified form]; Hydrogen Peroxide promotes the reaction [Niclosamide results in increased cleavage of PARP1 protein]; JUN protein affects the reaction [Niclosamide results in increased cleavage of PARP1 protein]; TP53 gene mutant form promotes the reaction [Niclosamide results in increased cleavage of PARP1 protein]; WNT7A protein affects the reaction [Niclosamide results in increased cleavage of PARP1 protein]
Niclosamide results in decreased expression of PARP1 protein		 CTD PMID:24750999 PMID:25174399 PMID:26917416 PMID:28500234 PMID:30258081 More... NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pbx1 PBX homeobox 1 increases expression ISO Niclosamide results in increased expression of PBX1 mRNA CTD PMID:36318118 NCBI chr13:80,278,766...80,588,563
Ensembl chr13:80,278,770...80,588,594 		JBrowse link
G Pbx2 PBX homeobox 2 increases expression ISO Niclosamide results in increased expression of PBX2 mRNA CTD PMID:36318118 NCBI chr20:4,151,500...4,156,425
Ensembl chr20:4,151,500...4,156,425 		JBrowse link
G Pbxip1 PBX homeobox interacting protein 1 increases expression ISO Niclosamide results in increased expression of PBXIP1 mRNA CTD PMID:36318118 NCBI chr 2:174,856,339...174,868,922
Ensembl chr 2:174,856,397...174,868,919 		JBrowse link
G Pc pyruvate carboxylase increases expression ISO Niclosamide results in increased expression of PC mRNA CTD PMID:22576131 NCBI chr 1:201,799,374...201,898,412
Ensembl chr 1:201,804,267...201,898,380 		JBrowse link
G Pcdh19 protocadherin 19 decreases expression ISO Niclosamide results in decreased expression of PCDH19 mRNA CTD PMID:36318118 NCBI chr  X:96,767,686...96,873,477
Ensembl chr  X:96,771,947...96,873,524 		JBrowse link
G Pcdh20 protocadherin 20 decreases expression ISO Niclosamide results in decreased expression of PCDH20 mRNA CTD PMID:36318118 NCBI chr15:64,425,534...64,431,790
Ensembl chr15:64,425,534...64,431,790 		JBrowse link
G Pcgf1 polycomb group ring finger 1 increases expression ISO Niclosamide results in increased expression of PCGF1 mRNA CTD PMID:36318118 NCBI chr 4:115,576,165...115,587,019
Ensembl chr 4:115,583,867...115,587,008 		JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression ISO Niclosamide results in decreased expression of PCNA mRNA CTD PMID:36318118 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Pdcd4 programmed cell death 4 increases expression ISO Niclosamide results in increased expression of PDCD4 mRNA CTD PMID:36318118 NCBI chr 1:252,921,342...252,944,278
Ensembl chr 1:252,921,392...252,944,275 		JBrowse link
G Pde4b phosphodiesterase 4B increases expression ISO Niclosamide results in increased expression of PDE4B mRNA CTD PMID:36318118 NCBI chr 5:116,799,819...117,369,155
Ensembl chr 5:116,799,971...117,367,696 		JBrowse link
G Pdgfrb platelet derived growth factor receptor beta increases expression ISO Niclosamide results in increased expression of PDGFRB mRNA CTD PMID:36318118 NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843 		JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 multiple interactions ISO Niclosamide inhibits the reaction [Oxygen deficiency results in increased expression of PDK1 mRNA] CTD PMID:36318118 NCBI chr 3:56,705,824...56,733,040
Ensembl chr 3:56,705,871...56,733,038 		JBrowse link
G Pdk3 pyruvate dehydrogenase kinase 3 decreases expression
multiple interactions		 ISO Niclosamide results in decreased expression of PDK3 mRNA
Niclosamide inhibits the reaction [Oxygen deficiency results in increased expression of PDK3 mRNA]		 CTD PMID:36318118 NCBI chr  X:58,486,699...58,553,533
Ensembl chr  X:58,486,554...58,553,557 		JBrowse link
G Pdlim4 PDZ and LIM domain 4 increases expression ISO Niclosamide results in increased expression of PDLIM4 mRNA CTD PMID:36318118 NCBI chr10:38,198,686...38,212,935
Ensembl chr10:38,198,689...38,212,938 		JBrowse link
G Pdzd7 PDZ domain containing 7 increases expression ISO Niclosamide results in increased expression of PDZD7 mRNA CTD PMID:36318118 NCBI chr 1:243,888,295...243,907,778
Ensembl chr 1:243,888,281...243,906,839 		JBrowse link
G Percc1 proline and glutamate rich with coiled coil 1 increases expression ISO Niclosamide results in increased expression of PERCC1 mRNA CTD PMID:36318118 NCBI chr10:14,187,858...14,190,634
Ensembl chr10:14,188,216...14,189,040
Ensembl chr10:14,188,216...14,189,040 		JBrowse link
G Pfkm phosphofructokinase, muscle decreases expression ISO Niclosamide results in decreased expression of PFKM mRNA CTD PMID:22576131 NCBI chr 7:129,221,679...129,259,192
Ensembl chr 7:129,221,653...129,259,192 		JBrowse link
G Pgk1 phosphoglycerate kinase 1 multiple interactions ISO Niclosamide inhibits the reaction [Oxygen deficiency results in increased expression of PGK1 mRNA] CTD PMID:36318118 NCBI chr  X:71,271,454...71,287,429
Ensembl chr  X:71,271,440...71,287,418 		JBrowse link
G Pgr progesterone receptor decreases expression ISO Niclosamide results in decreased expression of PGR mRNA CTD PMID:36318118 NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344 		JBrowse link
G Phf24 PHD finger protein 24 increases expression ISO Niclosamide results in increased expression of PHF24 mRNA CTD PMID:36318118 NCBI chr 5:57,143,428...57,171,054
Ensembl chr 5:57,142,632...57,168,497 		JBrowse link
G Phka2 phosphorylase kinase regulatory subunit alpha 2 decreases expression ISO Niclosamide results in decreased expression of PHKA2 mRNA CTD PMID:36318118 NCBI chr  X:34,170,959...34,293,498
Ensembl chr  X:34,171,323...34,293,466 		JBrowse link
G Phlda1 pleckstrin homology-like domain, family A, member 1 increases expression ISO Niclosamide results in increased expression of PHLDA1 mRNA CTD PMID:28284560 NCBI chr 7:46,967,433...46,969,637
Ensembl chr 7:46,967,409...46,969,861 		JBrowse link
G Phldb3 pleckstrin homology-like domain, family B, member 3 increases expression ISO Niclosamide results in increased expression of PHLDB3 mRNA CTD PMID:36318118 NCBI chr 1:80,201,083...80,219,541
Ensembl chr 1:80,201,578...80,219,534 		JBrowse link
G Phyhip phytanoyl-CoA 2-hydroxylase interacting protein increases expression ISO Niclosamide results in increased expression of PHYHIP mRNA CTD PMID:36318118 NCBI chr15:45,533,974...45,545,223
Ensembl chr15:45,533,974...45,545,221 		JBrowse link
G Pi15 peptidase inhibitor 15 decreases expression ISO Niclosamide results in decreased expression of PI15 mRNA CTD PMID:36318118 NCBI chr 5:1,395,094...1,423,213
Ensembl chr 5:1,395,094...1,423,213 		JBrowse link
G Pigw phosphatidylinositol glycan anchor biosynthesis, class W decreases expression ISO Niclosamide results in decreased expression of PIGW mRNA CTD PMID:36318118 NCBI chr10:69,746,996...69,782,656
Ensembl chr10:69,748,789...69,790,475 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha increases expression
multiple interactions		 ISO Niclosamide results in increased expression of PIK3CA mRNA
Niclosamide inhibits the reaction [PIK3CA protein modified form results in decreased expression of CCNG2 mRNA]; Niclosamide inhibits the reaction [PIK3CA protein modified form results in decreased expression of CSGALNACT1 mRNA]; Niclosamide inhibits the reaction [PIK3CA protein modified form results in decreased expression of CXCL8 mRNA]; Niclosamide inhibits the reaction [PIK3CA protein modified form results in decreased expression of HBP1 mRNA]; Niclosamide inhibits the reaction [PIK3CA protein modified form results in decreased expression of HEY1 mRNA]; Niclosamide inhibits the reaction [PIK3CA protein modified form results in increased expression of CCNE2 mRNA]; Niclosamide inhibits the reaction [PIK3CA protein modified form results in increased expression of DSCC1 mRNA]; Niclosamide inhibits the reaction [PIK3CA protein modified form results in increased expression of ENDOD1 mRNA]; Niclosamide inhibits the reaction [PIK3CA protein modified form results in increased expression of PPP2R1B mRNA]		 CTD PMID:27542212 PMID:29843133 NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032 		JBrowse link
G Pik3ip1 phosphoinositide-3-kinase interacting protein 1 increases expression ISO Niclosamide results in increased expression of PIK3IP1 mRNA CTD PMID:36318118 NCBI chr14:78,204,668...78,216,616
Ensembl chr14:78,204,053...78,216,608 		JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase increases expression ISO Niclosamide results in increased expression of PIM1 mRNA CTD PMID:36318118 NCBI chr20:7,554,921...7,559,174
Ensembl chr20:7,554,921...7,559,174 		JBrowse link
G Pkm pyruvate kinase M1/2 increases expression ISO Niclosamide results in increased expression of PKM mRNA CTD PMID:22576131 NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599 		JBrowse link
G Pla2g4c phospholipase A2 group IVC increases expression ISO Niclosamide results in increased expression of PLA2G4C mRNA CTD PMID:36318118 NCBI chr 1:74,237,714...74,275,757
Ensembl chr 1:74,236,211...74,274,656 		JBrowse link
G Plec plectin increases expression ISO Niclosamide results in increased expression of PLEC mRNA CTD PMID:36318118 NCBI chr 7:107,887,764...107,949,100
Ensembl chr 7:107,887,764...107,945,467 		JBrowse link
G Plekha2 pleckstrin homology domain containing A2 increases expression ISO Niclosamide results in increased expression of PLEKHA2 mRNA CTD PMID:36318118 NCBI chr16:66,938,684...67,000,661
Ensembl chr16:66,939,109...66,999,395 		JBrowse link
G Plekhg4 pleckstrin homology and RhoGEF domain containing G4 increases expression ISO Niclosamide results in increased expression of PLEKHG4 mRNA CTD PMID:36318118 NCBI chr19:33,251,788...33,266,490
Ensembl chr19:33,249,706...33,266,357 		JBrowse link
G Pnrc1 proline-rich nuclear receptor coactivator 1 increases expression ISO Niclosamide results in increased expression of PNRC1 mRNA CTD PMID:36318118 NCBI chr 5:47,647,070...47,657,832
Ensembl chr 5:47,647,071...47,650,161 		JBrowse link
G Pold4 DNA polymerase delta 4, accessory subunit increases expression ISO Niclosamide results in increased expression of POLD4 mRNA CTD PMID:36318118 NCBI chr 1:201,526,591...201,528,406
Ensembl chr 1:201,526,665...201,528,401 		JBrowse link
G Pou3f1 POU class 3 homeobox 1 increases expression ISO Niclosamide results in increased expression of POU3F1 mRNA CTD PMID:36318118 NCBI chr 5:136,910,391...136,913,371
Ensembl chr 5:136,910,391...136,913,371 		JBrowse link
G Pou5f1 POU class 5 homeobox 1 decreases phosphorylation ISO Niclosamide results in decreased phosphorylation of POU5F1 protein CTD PMID:23333246 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891 		JBrowse link
G Ppard peroxisome proliferator-activated receptor delta increases expression ISO Niclosamide results in increased expression of PPARD mRNA CTD PMID:22576131 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression ISO Niclosamide results in increased expression of PPARG mRNA CTD PMID:36318118 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ppef2 protein phosphatase with EF-hand domain 2 decreases expression ISO Niclosamide results in decreased expression of PPEF2 mRNA CTD PMID:36318118 NCBI chr14:15,797,414...15,831,620
Ensembl chr14:15,797,435...15,831,491 		JBrowse link
G Ppfia3 PTPRF interacting protein alpha 3 increases expression ISO Niclosamide results in increased expression of PPFIA3 mRNA CTD PMID:36318118 NCBI chr 1:95,817,110...95,845,950
Ensembl chr 1:95,817,110...95,845,798 		JBrowse link
G Ppil6 peptidylprolyl isomerase like 6 increases expression ISO Niclosamide results in increased expression of PPIL6 mRNA CTD PMID:36318118 NCBI chr20:44,989,509...45,017,833
Ensembl chr20:44,988,943...45,018,340 		JBrowse link
G Ppp1r12b protein phosphatase 1, regulatory subunit 12B increases expression ISO Niclosamide results in increased expression of PPP1R12B mRNA CTD PMID:36318118 NCBI chr13:46,199,418...46,397,108
Ensembl chr13:46,201,251...46,397,108 		JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression ISO Niclosamide results in increased expression of PPP1R15A mRNA CTD PMID:36318118 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171 		JBrowse link
G Ppp1r3b protein phosphatase 1, regulatory subunit 3B decreases expression ISO Niclosamide results in decreased expression of PPP1R3B mRNA CTD PMID:36318118 NCBI chr16:56,830,011...56,842,395
Ensembl chr16:56,829,660...56,842,406 		JBrowse link
G Ppp2cb protein phosphatase 2 catalytic subunit beta decreases expression ISO Niclosamide results in decreased expression of PPP2CB mRNA CTD PMID:22576131 NCBI chr16:58,558,119...58,579,325
Ensembl chr16:58,558,122...58,579,576 		JBrowse link
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha increases expression ISO Niclosamide results in increased expression of PPP2R1A mRNA CTD PMID:22576131 NCBI chr 1:60,540,223...60,559,467
Ensembl chr 1:60,540,194...60,560,129 		JBrowse link
G Ppp2r1b protein phosphatase 2 scaffold subunit A beta multiple interactions ISO Niclosamide inhibits the reaction [PIK3CA protein modified form results in increased expression of PPP2R1B mRNA] CTD PMID:27542212 NCBI chr 8:51,195,860...51,228,442
Ensembl chr 8:51,186,717...51,228,485 		JBrowse link
G Ppp2r2b protein phosphatase 2, regulatory subunit B, beta decreases expression ISO Niclosamide results in decreased expression of PPP2R2B mRNA CTD PMID:22576131 NCBI chr18:34,653,716...35,080,889
Ensembl chr18:34,653,721...35,081,025 		JBrowse link
G Ppp2r2c protein phosphatase 2, regulatory subunit B, gamma decreases expression ISO Niclosamide results in decreased expression of PPP2R2C mRNA CTD PMID:22576131 NCBI chr14:73,846,547...73,931,489
Ensembl chr14:73,846,547...73,931,864 		JBrowse link
G Prdm1 PR/SET domain 1 multiple interactions ISO Niclosamide affects the reaction [FAS protein mutant form affects the expression of PRDM1 mRNA] CTD PMID:33632240 NCBI chr20:47,959,858...47,981,488
Ensembl chr20:47,959,858...47,981,488 		JBrowse link
G Prkcd protein kinase C, delta increases expression ISO Niclosamide results in increased expression of PRKCD mRNA CTD PMID:36318118 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
G Prkcq protein kinase C, theta increases expression ISO Niclosamide results in increased expression of PRKCQ mRNA CTD PMID:22576131 NCBI chr17:67,246,394...67,379,049
Ensembl chr17:67,246,394...67,378,704 		JBrowse link
G Prpf8 pre-mRNA processing factor 8 decreases expression ISO Niclosamide results in decreased expression of PRPF8 mRNA CTD PMID:36318118 NCBI chr10:60,331,494...60,354,606
Ensembl chr10:60,331,494...60,354,606 		JBrowse link
G Prr29 proline rich 29 decreases expression ISO Niclosamide results in decreased expression of PRR29 mRNA CTD PMID:36318118 NCBI chr10:91,305,820...91,320,661
Ensembl chr10:91,305,723...91,310,439 		JBrowse link
G Prr36 proline rich 36 increases expression ISO Niclosamide results in increased expression of PRR36 mRNA CTD PMID:36318118 NCBI chr12:2,560,533...2,567,766
Ensembl chr12:2,560,536...2,567,742 		JBrowse link
G Psen2 presenilin 2 decreases expression ISO Niclosamide results in decreased expression of PSEN2 mRNA CTD PMID:36318118 NCBI chr13:91,967,506...91,993,240
Ensembl chr13:91,967,983...91,993,174 		JBrowse link
G Psmc3ip PSMC3 interacting protein decreases expression ISO Niclosamide results in decreased expression of PSMC3IP mRNA CTD PMID:36318118 NCBI chr10:86,024,281...86,027,928
Ensembl chr10:86,023,950...86,027,423 		JBrowse link
G Pten phosphatase and tensin homolog increases expression ISO Niclosamide results in increased expression of PTEN mRNA CTD PMID:29843133 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Ptger4 prostaglandin E receptor 4 decreases expression ISO Niclosamide results in decreased expression of PTGER4 mRNA CTD PMID:36318118 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670 		JBrowse link
G Ptges prostaglandin E synthase increases expression ISO Niclosamide results in increased expression of PTGES mRNA CTD PMID:36318118 NCBI chr 3:14,177,892...14,189,236 JBrowse link
G Ptk2b protein tyrosine kinase 2 beta increases expression ISO Niclosamide results in increased expression of PTK2B mRNA CTD PMID:36318118 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282 		JBrowse link
G Ptprg protein tyrosine phosphatase, receptor type, G decreases expression ISO Niclosamide results in decreased expression of PTPRG mRNA CTD PMID:36318118 NCBI chr15:12,871,706...13,552,186
Ensembl chr15:12,871,721...13,554,094 		JBrowse link
G Ptprh protein tyrosine phosphatase, receptor type, H increases expression ISO Niclosamide results in increased expression of PTPRH mRNA CTD PMID:36318118 NCBI chr 1:69,243,704...69,276,294
Ensembl chr 1:69,242,321...69,285,077 		JBrowse link
G Ptprt protein tyrosine phosphatase, receptor type, T decreases expression ISO Niclosamide results in decreased expression of PTPRT mRNA CTD PMID:36318118 NCBI chr 3:150,189,343...151,288,145
Ensembl chr 3:150,194,859...151,288,124 		JBrowse link
G R3hdm2 R3H domain containing 2 increases expression ISO Niclosamide results in increased expression of R3HDM2 mRNA CTD PMID:36318118 NCBI chr 7:63,212,519...63,340,574
Ensembl chr 7:63,232,346...63,340,540 		JBrowse link
G Rab26 RAB26, member RAS oncogene family increases expression ISO Niclosamide results in increased expression of RAB26 mRNA CTD PMID:36318118 NCBI chr10:13,553,395...13,558,063
Ensembl chr10:13,553,395...13,558,030 		JBrowse link
G Rab3a RAB3A, member RAS oncogene family increases expression ISO Niclosamide results in increased expression of RAB3A mRNA CTD PMID:36318118 NCBI chr16:18,684,185...18,688,297
Ensembl chr16:18,684,188...18,688,336 		JBrowse link
G Rab3il1 RAB3A interacting protein-like 1 increases expression ISO Niclosamide results in increased expression of RAB3IL1 mRNA CTD PMID:36318118 NCBI chr 1:206,646,168...206,682,718
Ensembl chr 1:206,646,155...206,679,972 		JBrowse link
G Rab7b Rab7b, member RAS oncogene family increases expression ISO Niclosamide results in increased expression of RAB7B mRNA CTD PMID:36318118 NCBI chr13:43,121,168...43,147,581
Ensembl chr13:43,121,226...43,147,581 		JBrowse link
G Rac2 Rac family small GTPase 2 increases expression ISO Niclosamide results in increased expression of RAC2 mRNA CTD PMID:36318118 NCBI chr 7:110,101,344...110,128,718
Ensembl chr 7:110,116,260...110,128,720 		JBrowse link
G Rad54l RAD54 like increases expression ISO Niclosamide results in increased expression of RAD54L mRNA CTD PMID:28284560 NCBI chr 5:129,575,431...129,605,100
Ensembl chr 5:129,575,378...129,605,070 		JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase decreases phosphorylation
decreases expression		 ISO Niclosamide analog results in decreased phosphorylation of RAF1 protein
Niclosamide analog results in decreased expression of RAF1 protein; Niclosamide results in decreased expression of RAF1 protein		 CTD PMID:28284560 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317 		JBrowse link
G Rasa4 RAS p21 protein activator 4 increases expression ISO Niclosamide results in increased expression of RASA4B mRNA CTD PMID:36318118 NCBI chr12:20,552,805...20,580,177
Ensembl chr12:20,552,806...20,580,147 		JBrowse link
G Rassf10 Ras association domain family member 10 decreases expression ISO Niclosamide results in decreased expression of RASSF10 mRNA CTD PMID:36318118 NCBI chr 1:167,058,277...167,063,591
Ensembl chr 1:167,058,099...167,063,572 		JBrowse link
G Rbm45 RNA binding motif protein 45 decreases expression ISO Niclosamide results in decreased expression of RBM45 mRNA CTD PMID:36318118 NCBI chr 3:61,305,973...61,320,950
Ensembl chr 3:61,305,924...61,320,952 		JBrowse link
G Rcn3 reticulocalbin 3 increases expression ISO Niclosamide results in increased expression of RCN3 mRNA CTD PMID:36318118 NCBI chr 1:95,564,503...95,573,762
Ensembl chr 1:95,564,380...95,573,725 		JBrowse link
G Rcor2 REST corepressor 2 increases expression ISO Niclosamide results in increased expression of RCOR2 mRNA CTD PMID:36318118 NCBI chr 1:204,453,403...204,461,403
Ensembl chr 1:204,454,360...204,460,838 		JBrowse link
G Reep6 receptor accessory protein 6 increases expression ISO Niclosamide results in increased expression of REEP6 mRNA CTD PMID:36318118 NCBI chr 7:9,373,927...9,380,845
Ensembl chr 7:9,373,927...9,380,597 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
decreases expression		 ISO
EXP		 Niclosamide affects the reaction [lipopolysaccharide, E coli O55-B5 affects the localization of RELA protein]; Niclosamide inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of and results in increased phosphorylation of RELA protein]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of RELA protein]; Niclosamide inhibits the reaction [Doxorubicin results in increased expression of RELA protein modified form]
Niclosamide results in decreased expression of RELA protein
Imatinib Mesylate promotes the reaction [Niclosamide results in decreased expression of RELA protein]; Niclosamide inhibits the reaction [[Lapatinib results in decreased susceptibility to Lapatinib] which results in increased phosphorylation of RELA protein]; Niclosamide inhibits the reaction [TNF protein affects the localization of RELA protein]; Niclosamide inhibits the reaction [TNF protein results in increased activity of RELA protein]; Niclosamide inhibits the reaction [WNT3A protein affects the localization of RELA protein]; Niclosamide promotes the reaction [Imatinib Mesylate results in decreased expression of RELA protein]; Niclosamide results in decreased phosphorylation of and affects the localization of RELA protein
Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of RELA protein modified form]		 CTD PMID:20215516 PMID:26116531 PMID:26643609 PMID:27492973 PMID:28318631 More... NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit increases expression ISO Niclosamide results in increased expression of RELB mRNA CTD PMID:36318118 NCBI chr 1:79,257,738...79,285,490
Ensembl chr 1:79,257,725...79,285,507 		JBrowse link
G Rep15 RAB15 effector protein decreases expression ISO Niclosamide results in decreased expression of REP15 mRNA CTD PMID:36318118 NCBI chr 4:179,951,935...179,953,008
Ensembl chr 4:179,951,935...179,953,008 		JBrowse link
G Rgma repulsive guidance molecule BMP co-receptor a decreases expression ISO Niclosamide results in decreased expression of RGMA mRNA CTD PMID:36318118 NCBI chr 1:127,128,934...127,172,918
Ensembl chr 1:127,128,934...127,172,918 		JBrowse link
G Rgs10 regulator of G-protein signaling 10 increases expression ISO Niclosamide results in increased expression of RGS10 mRNA CTD PMID:36318118 NCBI chr 1:182,946,334...182,987,729
Ensembl chr 1:182,946,336...182,987,697 		JBrowse link
G Rgs13 regulator of G-protein signaling 13 decreases expression ISO Niclosamide results in decreased expression of RGS13 mRNA CTD PMID:36318118 NCBI chr13:55,922,290...55,955,753
Ensembl chr13:55,922,395...55,955,648 		JBrowse link
G Rgs14 regulator of G-protein signaling 14 increases expression ISO Niclosamide results in increased expression of RGS14 mRNA CTD PMID:36318118 NCBI chr17:9,248,982...9,263,104
Ensembl chr17:9,249,019...9,263,104 		JBrowse link
G Rgs8 regulator of G-protein signaling 8 decreases expression ISO Niclosamide results in decreased expression of RGS8 mRNA CTD PMID:36318118 NCBI chr13:65,804,703...65,848,955
Ensembl chr13:65,804,797...65,846,807 		JBrowse link
G Rhobtb1 Rho-related BTB domain containing 1 increases expression ISO Niclosamide results in increased expression of RHOBTB1 mRNA CTD PMID:36318118 NCBI chr20:19,327,142...19,456,121
Ensembl chr20:19,327,155...19,403,012 		JBrowse link
G Rhof ras homolog family member F, filopodia associated multiple interactions ISO Niclosamide inhibits the reaction [Adenosine Triphosphate results in increased expression of RHOF mRNA] CTD PMID:29733962 NCBI chr12:33,422,375...33,446,689
Ensembl chr12:33,431,280...33,446,703 		JBrowse link
G Rilpl1 Rab interacting lysosomal protein-like 1 increases expression ISO Niclosamide results in increased expression of RILPL1 mRNA CTD PMID:36318118 NCBI chr12:32,071,870...32,109,687
Ensembl chr12:32,071,693...32,109,938 		JBrowse link
G Rin1 Ras and Rab interactor 1 increases expression ISO Niclosamide results in increased expression of RIN1 mRNA CTD PMID:36318118 NCBI chr 1:202,355,729...202,362,731
Ensembl chr 1:202,355,890...202,362,729 		JBrowse link
G Ripor3 RIPOR family member 3 increases expression ISO Niclosamide results in increased expression of FAM65C mRNA CTD PMID:28284560 NCBI chr 3:156,687,253...156,760,524
Ensembl chr 3:156,687,517...156,715,061 		JBrowse link
G Rnf122 ring finger protein 122 increases expression ISO Niclosamide results in increased expression of RNF122 mRNA CTD PMID:36318118 NCBI chr16:61,009,879...61,027,429
Ensembl chr16:61,009,879...61,027,448 		JBrowse link
G Rnf215 ring finger protein 215 increases expression ISO Niclosamide results in increased expression of RNF215 mRNA CTD PMID:36318118 NCBI chr14:79,006,659...79,013,091
Ensembl chr14:79,006,688...79,013,091 		JBrowse link
G Rnf227 ring finger protein 227 increases expression ISO Niclosamide results in increased expression of RNF227 mRNA CTD PMID:36318118 NCBI chr10:54,061,054...54,063,015
Ensembl chr10:54,059,947...54,063,010 		JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 decreases expression ISO Niclosamide results in decreased expression of ROCK1 mRNA; Niclosamide results in decreased expression of ROCK1 protein CTD PMID:29251334 NCBI chr18:1,114,532...1,236,345
Ensembl chr18:1,115,905...1,235,571 		JBrowse link
G Rps6 ribosomal protein S6 affects phosphorylation ISO Niclosamide affects the phosphorylation of RPS6 protein CTD PMID:27542212 NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602
Ensembl chr 5:101,371,136...101,374,602 		JBrowse link
G Rps6ka5 ribosomal protein S6 kinase A5 increases expression ISO Niclosamide results in increased expression of RPS6KA5 mRNA CTD PMID:36318118 NCBI chr 6:119,828,823...120,006,190
Ensembl chr 6:119,828,846...120,006,224 		JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 decreases phosphorylation ISO Niclosamide results in decreased phosphorylation of RPS6KB1 protein CTD PMID:27542212 PMID:30258081 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908 		JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 decreases expression ISO Niclosamide results in decreased expression of RRM2 mRNA CTD PMID:28284560 NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773 		JBrowse link
G Rsph4a radial spoke head component 4A decreases expression ISO Niclosamide results in decreased expression of RSPH4A mRNA CTD PMID:36318118 NCBI chr20:30,764,409...30,780,574
Ensembl chr20:30,764,409...30,780,574 		JBrowse link
G Rtn4r reticulon 4 receptor increases expression ISO Niclosamide results in increased expression of RTN4R mRNA CTD PMID:36318118 NCBI chr11:82,844,309...82,869,251
Ensembl chr11:82,844,309...82,869,466 		JBrowse link
G Rtn4rl1 reticulon 4 receptor-like 1 increases expression ISO Niclosamide results in increased expression of RTN4RL1 mRNA CTD PMID:36318118 NCBI chr10:60,043,246...60,116,977
Ensembl chr10:60,043,002...60,116,978 		JBrowse link
G Runx2 RUNX family transcription factor 2 decreases expression ISO Niclosamide results in decreased expression of RUNX2 mRNA CTD PMID:28824321 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167 		JBrowse link
G Rwdd3 RWD domain containing 3 decreases expression ISO Niclosamide results in decreased expression of RWDD3 mRNA CTD PMID:36318118 NCBI chr 2:209,233,622...209,254,842
Ensembl chr 2:209,233,622...209,248,853 		JBrowse link
G S100a4 S100 calcium-binding protein A4 decreases expression
multiple interactions		 ISO Niclosamide results in decreased expression of S100A4 mRNA; Niclosamide results in decreased expression of S100A4 protein
Niclosamide inhibits the reaction [Adenosine Triphosphate results in increased expression of S100A4 protein]
Niclosamide inhibits the reaction [Adenosine Triphosphate results in increased expression of S100A4 protein]; Niclosamide inhibits the reaction [MACC1 protein results in increased expression of S100A4 protein]		 CTD PMID:21685359 PMID:29733962 PMID:36008464 NCBI chr 2:176,090,951...176,093,258
Ensembl chr 2:176,091,804...176,093,254 		JBrowse link
G Samd11 sterile alpha motif domain containing 11 increases expression ISO Niclosamide results in increased expression of SAMD11 mRNA CTD PMID:36318118 NCBI chr 5:166,831,681...166,859,805
Ensembl chr 5:166,831,663...166,850,009 		JBrowse link
G Satb1 SATB homeobox 1 increases expression ISO Niclosamide results in increased expression of SATB1 mRNA CTD PMID:36318118 NCBI chr 9:4,677,817...4,773,061
Ensembl chr 9:4,680,920...4,753,251 		JBrowse link
G Saxo5 stabilizer of axonemal microtubules 5 increases expression ISO Niclosamide results in increased expression of SAXO5 mRNA CTD PMID:36318118 NCBI chr12:1,520,983...1,538,127
Ensembl chr12:1,521,014...1,538,118 		JBrowse link
G Scaper S-phase cyclin A-associated protein in the ER increases expression ISO Niclosamide results in increased expression of SCAPER mRNA CTD PMID:36318118 NCBI chr 8:55,932,717...56,332,222
Ensembl chr 8:55,933,306...56,332,122 		JBrowse link
G Scn7a sodium voltage-gated channel alpha subunit 7 decreases expression ISO Niclosamide results in decreased expression of SCN7A mRNA CTD PMID:36318118 NCBI chr 3:51,335,841...51,438,308
Ensembl chr 3:51,335,841...51,438,256 		JBrowse link
G Scrt1 scratch family transcriptional repressor 1 increases expression ISO Niclosamide results in increased expression of SCRT1 mRNA CTD PMID:36318118 NCBI chr 7:108,240,986...108,244,636
Ensembl chr 7:108,240,986...108,244,636 		JBrowse link
G Scrt2 scratch family transcriptional repressor 2 increases expression ISO Niclosamide results in increased expression of SCRT2 mRNA CTD PMID:36318118 NCBI chr 3:140,581,336...140,595,273
Ensembl chr 3:140,581,593...140,593,299 		JBrowse link
G Sdhaf4 succinate dehydrogenase complex assembly factor 4 increases expression ISO Niclosamide results in increased expression of SDHAF4 mRNA CTD PMID:36318118 NCBI chr 9:26,408,332...26,416,478 JBrowse link
G Sema3f semaphorin 3F increases expression ISO Niclosamide results in increased expression of SEMA3F mRNA CTD PMID:36318118 NCBI chr 8:108,357,629...108,386,569
Ensembl chr 8:108,357,629...108,387,083 		JBrowse link
G Sema4a semaphorin 4A increases expression ISO Niclosamide results in increased expression of SEMA4A mRNA CTD PMID:36318118 NCBI chr 2:173,896,432...173,917,903
Ensembl chr 2:173,896,439...173,914,442 		JBrowse link
G Sema6b semaphorin 6B increases expression ISO Niclosamide results in increased expression of SEMA6B mRNA CTD PMID:36318118 NCBI chr 9:950,939...967,905
Ensembl chr 9:950,939...961,521 		JBrowse link
G Septin5 septin 5 increases expression ISO Niclosamide results in increased expression of SEPTIN5 mRNA CTD PMID:36318118 NCBI chr11:82,373,601...82,379,393
Ensembl chr11:82,369,754...82,379,393 		JBrowse link
G Serpine1 serpin family E member 1 multiple interactions ISO Niclosamide inhibits the reaction [Doxorubicin results in increased expression of SERPINE1 mRNA] CTD PMID:28318631 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Serpine2 serpin family E member 2 multiple interactions EXP Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of SERPINE2 mRNA] CTD PMID:28318631 NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826 		JBrowse link
G Sertad4 SERTA domain containing 4 decreases expression ISO Niclosamide results in decreased expression of SERTAD4 mRNA CTD PMID:36318118 NCBI chr13:104,360,307...104,371,064
Ensembl chr13:104,360,307...104,370,546 		JBrowse link
G Sestd1 SEC14 and spectrin domain containing 1 decreases expression ISO Niclosamide results in decreased expression of SESTD1 mRNA CTD PMID:36318118 NCBI chr 3:62,123,590...62,220,759
Ensembl chr 3:62,129,887...62,220,546 		JBrowse link
G Setdb2 SET domain bifurcated histone lysine methyltransferase 2 increases expression ISO Niclosamide results in increased expression of SETDB2 mRNA CTD PMID:36318118 NCBI chr15:33,553,657...33,606,586
Ensembl chr15:33,453,952...33,606,470 		JBrowse link
G Sfxn2 sideroflexin 2 decreases expression ISO Niclosamide results in decreased expression of SFXN2 mRNA CTD PMID:36318118 NCBI chr 1:245,447,014...245,459,312
Ensembl chr 1:245,447,015...245,468,411
Ensembl chr 1:245,447,015...245,468,411 		JBrowse link
G Sgpp2 sphingosine-1-phosphate phosphatase 2 decreases expression ISO Niclosamide results in decreased expression of SGPP2 mRNA CTD PMID:36318118 NCBI chr 9:79,762,658...79,884,665
Ensembl chr 9:79,763,284...79,880,457 		JBrowse link
G Sh2b2 SH2B adaptor protein 2 increases expression ISO Niclosamide results in increased expression of SH2B2 mRNA CTD PMID:36318118 NCBI chr12:20,427,057...20,456,845
Ensembl chr12:20,429,043...20,456,844 		JBrowse link
G Sh3tc2 SH3 domain and tetratricopeptide repeats 2 decreases expression ISO Niclosamide results in decreased expression of SH3TC2 mRNA CTD PMID:36318118 NCBI chr18:55,416,383...55,477,419
Ensembl chr18:55,416,413...55,483,083 		JBrowse link
G Shank3 SH3 and multiple ankyrin repeat domains 3 increases expression ISO Niclosamide results in increased expression of SHANK3 mRNA CTD PMID:36318118 NCBI chr 7:120,568,707...120,630,796
Ensembl chr 7:120,570,402...120,630,374 		JBrowse link
G Shfl shiftless antiviral inhibitor of ribosomal frameshifting increases expression ISO Niclosamide results in increased expression of SHFL mRNA CTD PMID:36318118 NCBI chr 8:19,408,298...19,414,084
Ensembl chr 8:19,408,333...19,413,971 		JBrowse link
G Shisa4 shisa family member 4 increases expression ISO Niclosamide results in increased expression of SHISA4 mRNA CTD PMID:36318118 NCBI chr13:46,799,735...46,803,816
Ensembl chr13:46,799,772...46,803,998 		JBrowse link
G Six5 SIX homeobox 5 increases expression ISO Niclosamide results in increased expression of SIX5 mRNA CTD PMID:36318118 NCBI chr 1:78,740,812...78,745,890
Ensembl chr 1:78,741,367...78,745,890 		JBrowse link
G Slc16a14 solute carrier family 16, member 14 increases expression ISO Niclosamide results in increased expression of SLC16A14 mRNA CTD PMID:36318118 NCBI chr 9:86,110,066...86,137,546
Ensembl chr 9:86,112,894...86,137,318 		JBrowse link
G Slc16a2 solute carrier family 16 member 2 increases expression ISO Niclosamide results in increased expression of SLC16A2 mRNA CTD PMID:36318118 NCBI chr  X:68,725,365...68,848,572
Ensembl chr  X:68,723,261...68,848,771 		JBrowse link
G Slc16a9 solute carrier family 16, member 9 increases expression ISO Niclosamide results in increased expression of SLC16A9 mRNA CTD PMID:36318118 NCBI chr20:18,335,862...18,377,125
Ensembl chr20:18,335,862...18,377,022 		JBrowse link
G Slc17a7 solute carrier family 17 member 7 increases expression ISO Niclosamide results in increased expression of SLC17A7 mRNA CTD PMID:36318118 NCBI chr 1:95,649,709...95,661,591
Ensembl chr 1:95,649,745...95,661,588 		JBrowse link
G Slc22a18 solute carrier family 22, member 18 increases expression ISO Niclosamide results in increased expression of SLC22A18 mRNA CTD PMID:36318118 NCBI chr 1:198,670,626...198,694,977
Ensembl chr 1:198,671,731...198,694,975 		JBrowse link
G Slc29a4 solute carrier family 29 member 4 increases expression ISO Niclosamide results in increased expression of SLC29A4 mRNA CTD PMID:36318118 NCBI chr12:11,853,540...11,884,660
Ensembl chr12:11,853,540...11,874,834 		JBrowse link
G Slc2a1 solute carrier family 2 member 1 decreases expression ISO Niclosamide results in decreased expression of SLC2A1 mRNA CTD PMID:22576131 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416 		JBrowse link
G Slc2a12 solute carrier family 2 member 12 increases expression ISO Niclosamide results in increased expression of SLC2A12 mRNA CTD PMID:36318118 NCBI chr 1:22,803,068...22,862,204
Ensembl chr 1:22,804,418...22,860,971 		JBrowse link
G Slc2a3 solute carrier family 2 member 3 decreases expression
increases expression		 ISO Niclosamide results in decreased expression of SLC2A3 mRNA
Niclosamide results in increased expression of SLC2A3 mRNA		 CTD PMID:22576131 PMID:36318118 NCBI chr 4:155,960,944...156,026,000
Ensembl chr 4:155,960,946...156,025,472 		JBrowse link
G Slc35d3 solute carrier family 35, member D3 decreases expression ISO Niclosamide results in decreased expression of SLC35D3 mRNA CTD PMID:36318118 NCBI chr 1:14,565,482...14,573,581
Ensembl chr 1:14,569,687...14,573,159 		JBrowse link
G Slc43a1 solute carrier family 43 member 1 increases expression ISO Niclosamide results in increased expression of SLC43A1 mRNA CTD PMID:36318118 NCBI chr 3:69,920,586...69,946,768
Ensembl chr 3:69,920,649...69,946,768 		JBrowse link
G Slc4a3 solute carrier family 4 member 3 increases expression ISO Niclosamide results in increased expression of SLC4A3 mRNA CTD PMID:36318118 NCBI chr 9:77,036,243...77,053,940
Ensembl chr 9:77,037,016...77,049,105 		JBrowse link
G Slc6a19 solute carrier family 6 member 19 decreases expression ISO Niclosamide results in decreased expression of SLC6A19 mRNA CTD PMID:36318118 NCBI chr 1:29,586,191...29,604,964
Ensembl chr 1:29,586,195...29,604,962 		JBrowse link
G Slco5a1 solute carrier organic anion transporter family, member 5A1 increases expression ISO Niclosamide results in increased expression of SLCO5A1 mRNA CTD PMID:36318118 NCBI chr 5:6,228,938...6,358,124
Ensembl chr 5:6,228,973...6,352,913 		JBrowse link
G Smad2 SMAD family member 2 multiple interactions ISO Niclosamide inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD2 protein] CTD PMID:36870549 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323 		JBrowse link
G Smad3 SMAD family member 3 multiple interactions ISO
EXP		 HIPK2 protein inhibits the reaction [Niclosamide inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein]]; Niclosamide inhibits the reaction [TGFB1 protein promotes the reaction [SMAD3 protein binds to HIPK2 promoter]]; Niclosamide inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein]
Niclosamide inhibits the reaction [Doxorubicin results in increased phosphorylation of SMAD3 protein]		 CTD PMID:28318631 PMID:36870549 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
G Smc1b structural maintenance of chromosomes 1B decreases expression ISO Niclosamide results in decreased expression of SMC1B mRNA CTD PMID:36318118 NCBI chr 7:116,180,987...116,242,778
Ensembl chr 7:116,180,987...116,242,744 		JBrowse link
G Smim10l2a small integral membrane protein 10 like 2A increases expression ISO Niclosamide results in increased expression of SMIM10L2A mRNA CTD PMID:36318118 NCBI chr  X:134,151,325...134,154,647 JBrowse link
G Smim14 small integral membrane protein 14 increases expression ISO Niclosamide results in increased expression of SMIM14 mRNA CTD PMID:36318118 NCBI chr14:42,783,361...42,829,762
Ensembl chr14:42,783,332...42,829,760 		JBrowse link
G Smim45 small integral membrane protein 45 increases expression ISO Niclosamide results in increased expression of SMIM45 mRNA CTD PMID:36318118 NCBI chr 7:113,769,175...113,773,952
Ensembl chr 7:113,765,468...113,773,339 		JBrowse link
G Smn1 survival of motor neuron 1, telomeric decreases expression ISO Niclosamide results in decreased expression of SMN1 mRNA CTD PMID:36318118 NCBI chr 2:31,490,018...31,501,065
Ensembl chr 2:31,490,015...31,501,060 		JBrowse link
G Smox spermine oxidase increases expression ISO Niclosamide results in increased expression of SMOX mRNA CTD PMID:36318118 NCBI chr 3:118,731,814...118,767,242
Ensembl chr 3:118,731,900...118,765,710 		JBrowse link
G Snai1 snail family transcriptional repressor 1 multiple interactions
decreases expression
increases expression		 ISO
EXP		 Niclosamide inhibits the reaction [Doxorubicin results in increased expression of SNAI1 mRNA]
Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of SNAI1 mRNA]
Niclosamide inhibits the reaction [[Lapatinib results in decreased susceptibility to Lapatinib] which results in increased expression of SNAI1 protein]; Niclosamide inhibits the reaction [TGFB1 protein results in increased phosphorylation of SNAI1 protein]
Niclosamide results in decreased expression of SNAI1 mRNA; Niclosamide results in decreased expression of SNAI1 protein
Niclosamide results in increased expression of SNAI1 mRNA		 CTD PMID:26643609 PMID:28318631 PMID:30143678 PMID:36318118 PMID:36870549 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969 		JBrowse link
G Snai2 snail family transcriptional repressor 2 multiple interactions
decreases expression		 ISO Niclosamide inhibits the reaction [TGFB1 protein results in increased phosphorylation of SNAI2 protein]; WNT7A protein affects the reaction [Niclosamide results in increased expression of SNAI2 protein]
Niclosamide results in decreased expression of SNAI2 protein		 CTD PMID:25174399 PMID:36870549 NCBI chr11:86,182,788...86,186,203
Ensembl chr11:86,181,909...86,186,200 		JBrowse link
G Snca synuclein alpha increases expression ISO Niclosamide results in increased expression of SNCA mRNA CTD PMID:36318118 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
G Snorc secondary ossification center associated regulator of chondrocyte maturation increases expression ISO Niclosamide results in increased expression of SNORC mRNA CTD PMID:36318118 NCBI chr 9:88,140,510...88,145,527
Ensembl chr 9:88,140,419...88,145,891 		JBrowse link
G Socs2 suppressor of cytokine signaling 2 increases expression ISO Niclosamide results in increased expression of SOCS2 mRNA CTD PMID:36318118 NCBI chr 7:30,006,360...30,045,161
Ensembl chr 7:30,008,578...30,043,548 		JBrowse link
G Socs3 suppressor of cytokine signaling 3 increases expression ISO Niclosamide results in increased expression of SOCS3 mRNA CTD PMID:36318118 NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787 		JBrowse link
G Sox8 SRY-box transcription factor 8 increases expression ISO Niclosamide results in increased expression of SOX8 mRNA CTD PMID:36318118 NCBI chr10:14,584,829...14,589,818
Ensembl chr10:14,584,829...14,589,818 		JBrowse link
G Sptbn4 spectrin, beta, non-erythrocytic 4 increases expression ISO Niclosamide results in increased expression of SPTBN4 mRNA CTD PMID:36318118 NCBI chr 1:82,650,750...82,738,345
Ensembl chr 1:82,650,751...82,737,228 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions ISO Niclosamide inhibits the reaction [[Lapatinib results in decreased susceptibility to Lapatinib] which results in increased phosphorylation of SRC protein] CTD PMID:26643609 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Srsf2 serine and arginine rich splicing factor 2 decreases expression ISO Niclosamide results in decreased expression of SRSF2 mRNA CTD PMID:36318118 NCBI chr10:102,052,158...102,055,365
Ensembl chr10:102,052,314...102,055,338 		JBrowse link
G Srsf6 serine and arginine rich splicing factor 6 decreases expression ISO Niclosamide results in decreased expression of SRSF6 mRNA CTD PMID:36318118 NCBI chr 3:151,589,546...151,594,869
Ensembl chr 3:151,589,535...151,594,860 		JBrowse link
G St8sia4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 increases expression ISO Niclosamide results in increased expression of ST8SIA4 mRNA CTD PMID:36318118 NCBI chr 9:95,990,131...96,084,661
Ensembl chr 9:95,993,503...96,084,653 		JBrowse link
G Stac2 SH3 and cysteine rich domain 2 increases expression ISO Niclosamide results in increased expression of STAC2 mRNA CTD PMID:36318118 NCBI chr10:83,032,418...83,048,260
Ensembl chr10:83,032,417...83,048,260 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 decreases phosphorylation
decreases expression
multiple interactions		 ISO Niclosamide analog results in decreased phosphorylation of STAT3 protein; Niclosamide results in decreased phosphorylation of STAT3 protein
Niclosamide analog results in decreased expression of STAT3 protein; Niclosamide results in decreased expression of STAT3 protein
[Niclosamide inhibits the reaction [Erlotinib Hydrochloride results in increased phosphorylation of STAT3 protein]] which results in increased susceptibility to Erlotinib Hydrochloride; enzalutamide promotes the reaction [Niclosamide results in decreased phosphorylation of and results in decreased activity of STAT3 protein]; Niclosamide inhibits the reaction [EGF protein results in increased phosphorylation of STAT3 protein]; Niclosamide inhibits the reaction [Erlotinib Hydrochloride results in increased phosphorylation of STAT3 protein]; Niclosamide inhibits the reaction [IL6 protein results in increased phosphorylation of and results in increased activity of STAT3 protein]; Niclosamide inhibits the reaction [STAT3 protein results in decreased susceptibility to enzalutamide]; Niclosamide inhibits the reaction [TNFSF11 protein results in increased phosphorylation of STAT3 protein]; Niclosamide results in decreased expression of and results in decreased phosphorylation of and results in decreased activity of STAT3 protein; Niclosamide results in decreased expression of and results in decreased phosphorylation of STAT3 protein
Niclosamide affects the reaction [FAS protein mutant form affects the phosphorylation of STAT3 protein]		 CTD PMID:23333246 PMID:23894143 PMID:24552774 PMID:25970160 PMID:26116531 More... NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A increases expression ISO Niclosamide results in increased expression of STAT5A mRNA CTD PMID:36318118 NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866 		JBrowse link
G Stc2 stanniocalcin 2 increases expression ISO Niclosamide results in increased expression of STC2 mRNA CTD PMID:36318118 NCBI chr10:16,251,046...16,260,815
Ensembl chr10:16,250,853...16,262,973 		JBrowse link
G Stmn4 stathmin 4 increases expression ISO Niclosamide results in increased expression of STMN4 mRNA CTD PMID:36318118 NCBI chr15:40,541,305...40,559,253
Ensembl chr15:40,541,357...40,559,253 		JBrowse link
G Strc stereocilin increases expression ISO Niclosamide results in increased expression of STRC mRNA CTD PMID:36318118 NCBI chr 3:108,335,920...108,355,114
Ensembl chr 3:108,335,747...108,354,134 		JBrowse link
G Stx3 syntaxin 3 increases expression ISO Niclosamide results in increased expression of STX3 mRNA CTD PMID:36318118 NCBI chr 1:208,617,018...208,686,240
Ensembl chr 1:208,639,115...208,685,805 		JBrowse link
G Supt3h SPT3 homolog, SAGA and STAGA complex component increases expression ISO Niclosamide results in increased expression of SUPT3H mRNA CTD PMID:36318118 NCBI chr 9:15,878,296...16,206,768
Ensembl chr 9:15,868,287...16,206,706 		JBrowse link
G Syt17 synaptotagmin 17 increases expression ISO Niclosamide results in increased expression of SYT17 mRNA CTD PMID:36318118 NCBI chr 1:172,695,275...172,761,906
Ensembl chr 1:172,696,120...172,761,960 		JBrowse link
G Syt3 synaptotagmin 3 increases expression ISO Niclosamide results in increased expression of SYT3 mRNA CTD PMID:36318118 NCBI chr 1:94,880,835...94,895,518
Ensembl chr 1:94,881,247...94,895,246 		JBrowse link
G Syt5 synaptotagmin 5 increases expression ISO Niclosamide results in increased expression of SYT5 mRNA CTD PMID:36318118 NCBI chr 1:69,277,351...69,285,071
Ensembl chr 1:69,277,351...69,285,067 		JBrowse link
G Syt9 synaptotagmin 9 decreases expression ISO Niclosamide results in decreased expression of SYT9 mRNA CTD PMID:36318118 NCBI chr 1:161,275,882...161,456,384
Ensembl chr 1:161,275,734...161,455,007 		JBrowse link
G Tacc3 transforming, acidic coiled-coil containing protein 3 decreases expression ISO Niclosamide results in decreased expression of TACC3 mRNA CTD PMID:28284560 NCBI chr14:77,051,209...77,065,343
Ensembl chr14:77,051,215...77,065,219 		JBrowse link
G Tamalin trafficking regulator and scaffold protein tamalin increases expression ISO Niclosamide results in increased expression of TAMALIN mRNA CTD PMID:36318118 NCBI chr 7:132,338,900...132,359,519
Ensembl chr 7:132,338,900...132,346,666 		JBrowse link
G Tbc1d10a TBC1 domain family, member 10a increases expression ISO Niclosamide results in increased expression of TBC1D10A mRNA CTD PMID:36318118 NCBI chr14:79,051,822...79,083,603
Ensembl chr14:79,055,432...79,083,600 		JBrowse link
G Tbc1d17 TBC1 domain family, member 17 increases expression ISO Niclosamide results in increased expression of TBC1D17 mRNA CTD PMID:36318118 NCBI chr 1:95,324,770...95,333,156
Ensembl chr 1:95,322,737...95,333,005 		JBrowse link
G Tbx6 T-box transcription factor 6 increases expression ISO Niclosamide results in increased expression of TBX6 mRNA CTD PMID:36318118 NCBI chr 1:181,387,851...181,392,762
Ensembl chr 1:181,388,684...181,392,593 		JBrowse link
G Tcf7 transcription factor 7 multiple interactions
decreases expression		 ISO Niclosamide affects the reaction [FAS protein mutant form affects the expression of TCF7 protein]
Niclosamide results in decreased expression of TCF7 mRNA		 CTD PMID:33632240 PMID:36318118 NCBI chr10:36,423,443...36,454,350
Ensembl chr10:36,423,445...36,453,535 		JBrowse link
G Tcim transcriptional and immune response regulator increases expression ISO Niclosamide results in increased expression of TCIM mRNA CTD PMID:28284560 NCBI chr16:67,595,762...67,597,055
Ensembl chr16:67,593,410...67,597,581 		JBrowse link
G Tcp11l2 t-complex 11 like 2 increases expression ISO Niclosamide results in increased expression of TCP11L2 mRNA CTD PMID:36318118 NCBI chr 7:19,150,241...19,185,135
Ensembl chr 7:19,150,252...19,185,095 		JBrowse link
G Tdrp testis development related protein increases expression ISO Niclosamide results in increased expression of TDRP mRNA CTD PMID:36318118 NCBI chr16:75,624,047...75,652,635
Ensembl chr16:75,624,907...75,652,420 		JBrowse link
G Tead3 TEA domain transcription factor 3 increases expression ISO Niclosamide results in increased expression of TEAD3 mRNA CTD PMID:36318118 NCBI chr20:6,392,053...6,411,446
Ensembl chr20:6,392,053...6,411,446 		JBrowse link
G Tent5a terminal nucleotidyltransferase 5A decreases expression ISO Niclosamide results in decreased expression of TENT5A mRNA CTD PMID:36318118 NCBI chr 8:86,222,294...86,229,045
Ensembl chr 8:86,225,357...86,229,045 		JBrowse link
G Tent5b terminal nucleotidyltransferase 5B increases expression ISO Niclosamide results in increased expression of TENT5B mRNA CTD PMID:36318118 NCBI chr 5:145,695,358...145,702,668
Ensembl chr 5:145,695,362...145,706,073 		JBrowse link
G Tesmin testis expressed metallothionein like protein increases expression ISO Niclosamide results in increased expression of TESMIN mRNA CTD PMID:36318118 NCBI chr 1:200,629,688...200,648,434
Ensembl chr 1:200,630,144...200,648,433 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO
EXP		 HIPK2 protein inhibits the reaction [Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of FN1 mRNA]]; HIPK2 protein inhibits the reaction [Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of VIM mRNA]]; HIPK2 protein inhibits the reaction [Niclosamide inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein]]; Niclosamide inhibits the reaction [TGFB1 protein promotes the reaction [SMAD3 protein binds to HIPK2 promoter]]; Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of CDH12 protein]; Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of FN1 mRNA]; Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of HIPK2 protein]; Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of VIM mRNA]; Niclosamide inhibits the reaction [TGFB1 protein results in increased phosphorylation of ACTA2 protein]; Niclosamide inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD2 protein]; Niclosamide inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein]; Niclosamide inhibits the reaction [TGFB1 protein results in increased phosphorylation of SNAI1 protein]; Niclosamide inhibits the reaction [TGFB1 protein results in increased phosphorylation of SNAI2 protein]; Niclosamide inhibits the reaction [TGFB1 protein results in increased phosphorylation of VIM protein]
Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of CCL2 mRNA]; Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of CCL20 mRNA]; Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of FAS mRNA]; Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of HES1 mRNA]; Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of HEY1 mRNA]; Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of HEY2 mRNA]; Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of HIPK2 mRNA]; Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of HIPK2 protein]; Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of ICAM1 mRNA]; Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of MMP7 mRNA]; Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of RELA protein modified form]; Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of SERPINE2 mRNA]; Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of SNAI1 mRNA]; Niclosamide inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein]		 CTD PMID:28318631 PMID:36870549 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tgfb1i1 transforming growth factor beta 1 induced transcript 1 increases expression ISO Niclosamide results in increased expression of TGFB1I1 mRNA CTD PMID:36318118 NCBI chr 1:182,828,553...182,835,465
Ensembl chr 1:182,828,544...182,837,080 		JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 decreases expression ISO Niclosamide results in decreased expression of TGFBR3 mRNA CTD PMID:36318118 NCBI chr14:2,489,397...2,665,383
Ensembl chr14:2,489,397...2,663,341 		JBrowse link
G Thbs4 thrombospondin 4 increases expression ISO Niclosamide results in increased expression of THBS4 mRNA CTD PMID:36318118 NCBI chr 2:23,983,158...24,025,289
Ensembl chr 2:23,983,158...24,026,313 		JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase decreases expression ISO Niclosamide results in decreased expression of TIGAR mRNA CTD PMID:36318118 NCBI chr 4:159,927,136...159,946,077
Ensembl chr 4:159,927,139...159,946,029 		JBrowse link
G Tigd3 tigger transposable element derived 3 decreases expression ISO Niclosamide results in decreased expression of TIGD3 mRNA CTD PMID:36318118 NCBI chr 1:203,178,456...203,182,775
Ensembl chr 1:203,178,460...203,181,272 		JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 increases expression ISO Niclosamide results in increased expression of TIMP2 mRNA CTD PMID:30143678 NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611 		JBrowse link
G Tk1 thymidine kinase 1 decreases expression ISO Niclosamide results in decreased expression of TK1 mRNA CTD PMID:28284560 PMID:36318118 NCBI chr10:103,034,755...103,046,125
Ensembl chr10:103,031,521...103,046,920 		JBrowse link
G Tle4 TLE family member 4, transcriptional corepressor decreases expression ISO Niclosamide results in decreased expression of TLE4 mRNA CTD PMID:36318118 NCBI chr 1:211,661,738...211,798,458
Ensembl chr 1:211,661,746...211,797,862 		JBrowse link
G Tmc6 transmembrane channel like 6 increases expression ISO Niclosamide results in increased expression of TMC6 mRNA CTD PMID:36318118 NCBI chr10:102,982,059...102,999,509
Ensembl chr10:102,971,229...102,998,960 		JBrowse link
G Tmem151b transmembrane protein 151B increases expression ISO Niclosamide results in increased expression of TMEM151B mRNA CTD PMID:36318118 NCBI chr 9:15,456,446...15,464,289
Ensembl chr 9:15,455,801...15,464,302 		JBrowse link
G Tmem231 transmembrane protein 231 increases expression ISO Niclosamide results in increased expression of TMEM231 mRNA CTD PMID:36318118 NCBI chr19:39,883,077...39,904,296
Ensembl chr19:39,883,077...39,904,269 		JBrowse link
G Tmem256 transmembrane protein 256 increases expression ISO Niclosamide results in increased expression of TMEM256 mRNA CTD PMID:36318118 NCBI chr10:54,559,030...54,560,146
Ensembl chr10:54,555,360...54,560,120 		JBrowse link
G Tmem42 transmembrane protein 42 increases expression ISO Niclosamide results in increased expression of TMEM42 mRNA CTD PMID:36318118 NCBI chr 8:122,674,793...122,677,290
Ensembl chr 8:122,674,070...122,677,276 		JBrowse link
G Tmem45a transmembrane protein 45A increases expression ISO Niclosamide results in increased expression of TMEM45A mRNA CTD PMID:36318118 NCBI chr11:43,713,309...43,799,526
Ensembl chr11:43,713,782...43,799,526 		JBrowse link
G Tmem50b transmembrane protein 50B decreases expression ISO Niclosamide results in decreased expression of TMEM50B mRNA CTD PMID:36318118 NCBI chr11:30,804,835...30,837,675
Ensembl chr11:30,804,837...30,837,661 		JBrowse link
G Tmem52 transmembrane protein 52 increases expression ISO Niclosamide results in increased expression of TMEM52 mRNA CTD PMID:36318118 NCBI chr 5:166,048,669...166,050,423
Ensembl chr 5:166,046,565...166,050,433 		JBrowse link
G Tmem53 transmembrane protein 53 increases expression ISO Niclosamide results in increased expression of TMEM53 mRNA CTD PMID:36318118 NCBI chr 5:130,721,780...130,737,692
Ensembl chr 5:130,721,659...130,737,692 		JBrowse link
G Tmem63c transmembrane protein 63c increases expression ISO Niclosamide results in increased expression of TMEM63C mRNA CTD PMID:36318118 NCBI chr 6:106,667,389...106,738,778
Ensembl chr 6:106,672,934...106,736,990 		JBrowse link
G Tmem8b transmembrane protein 8B increases expression ISO Niclosamide results in increased expression of TMEM8B mRNA CTD PMID:36318118 NCBI chr 5:57,919,473...57,948,419
Ensembl chr 5:57,919,804...57,946,772 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases activity		 ISO Niclosamide inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of TNF mRNA]; Niclosamide inhibits the reaction [Doxorubicin results in increased expression of TNF mRNA]; Niclosamide inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
Niclosamide results in decreased activity of TNF protein
Niclosamide inhibits the reaction [TNF protein affects the localization of CTNNB1 protein]; Niclosamide inhibits the reaction [TNF protein affects the localization of FOXM1 protein]; Niclosamide inhibits the reaction [TNF protein affects the localization of RELA protein]; Niclosamide inhibits the reaction [TNF protein results in increased activity of AKT1 protein]; Niclosamide inhibits the reaction [TNF protein results in increased activity of RELA protein]; Niclosamide inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]; Niclosamide inhibits the reaction [TNF protein results in increased expression of BCL2 mRNA]; Niclosamide inhibits the reaction [TNF protein results in increased expression of BCL2L1 mRNA]; Niclosamide inhibits the reaction [TNF protein results in increased expression of CCND1 mRNA]; Niclosamide inhibits the reaction [TNF protein results in increased expression of MYC mRNA]; Niclosamide inhibits the reaction [TNF protein results in increased phosphorylation of NFKBIA protein]		 CTD PMID:20215516 PMID:24561310 PMID:27492973 PMID:28318631 PMID:33524445 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions ISO Niclosamide inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 mRNA]; Niclosamide inhibits the reaction [TNFSF11 protein results in increased expression of ATP6V0D2 mRNA]; Niclosamide inhibits the reaction [TNFSF11 protein results in increased expression of CTSK mRNA]; Niclosamide inhibits the reaction [TNFSF11 protein results in increased expression of FOS protein]; Niclosamide inhibits the reaction [TNFSF11 protein results in increased expression of ITGAV mRNA]; Niclosamide inhibits the reaction [TNFSF11 protein results in increased expression of ITGB3 mRNA]; Niclosamide inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 mRNA]; Niclosamide inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 protein]; Niclosamide inhibits the reaction [TNFSF11 protein results in increased expression of OSCAR mRNA]; Niclosamide inhibits the reaction [TNFSF11 protein results in increased phosphorylation of AKT1 protein]; Niclosamide inhibits the reaction [TNFSF11 protein results in increased phosphorylation of STAT3 protein]
Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of ACP5 mRNA]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of and affects the localization of NFATC1 protein]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of CASP3 protein modified form]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of FOS mRNA]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of ITGB3 mRNA]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of MMP9 mRNA]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of NFATC1 mRNA]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of OCSTAMP mRNA]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of OSCAR mRNA]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of TRAF6 protein]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of MAPK1 protein]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of MAPK3 protein]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of MAPK8 protein]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of MAPK9 protein]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of NFKBIA protein]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of RELA protein]		 CTD PMID:26792726 PMID:28824321 NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445 		JBrowse link
G Tnfsf4 TNF superfamily member 4 increases expression ISO Niclosamide results in increased expression of TNFSF4 mRNA CTD PMID:36318118 NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788 		JBrowse link
G Top2a DNA topoisomerase II alpha affects binding ISO Niclosamide binds to TOP2A protein CTD PMID:36870549 NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874 		JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases expression
increases response to substance
decreases response to substance		 ISO [Niclosamide binds to Polyethyleneimine] which results in increased expression of TP53 mRNA; TP53 gene mutant form inhibits the reaction [Niclosamide results in increased expression of ALOX12B mRNA]; TP53 gene mutant form inhibits the reaction [Niclosamide results in increased expression of ALOX5 mRNA]; TP53 gene mutant form inhibits the reaction [Niclosamide results in increased expression of BBC3 mRNA]; TP53 gene mutant form inhibits the reaction [Niclosamide results in increased expression of CDKN1A mRNA]; TP53 gene mutant form promotes the reaction [Niclosamide results in increased cleavage of CASP3 protein]; TP53 gene mutant form promotes the reaction [Niclosamide results in increased cleavage of CASP9 protein]; TP53 gene mutant form promotes the reaction [Niclosamide results in increased cleavage of PARP1 protein]; TP53 protein mutant form inhibits the reaction [Niclosamide results in increased expression of ALOX12B mRNA]; TP53 protein mutant form inhibits the reaction [Niclosamide results in increased expression of ALOX5 mRNA]; TP53 protein mutant form inhibits the reaction [Niclosamide results in increased expression of CDKN1A mRNA]
Niclosamide results in increased expression of TRP53 protein
TP53 gene mutant form results in increased susceptibility to Niclosamide; TP53 protein mutant form results in increased susceptibility to Niclosamide
TP53 protein results in decreased susceptibility to Niclosamide
Niclosamide results in increased expression of TP53 mRNA; Niclosamide results in increased expression of TP53 protein
[TP53 protein mutant form results in increased susceptibility to Niclosamide] which results in increased abundance of adrenic acid; [TP53 protein mutant form results in increased susceptibility to Niclosamide] which results in increased abundance of Arachidonic Acid; [TP53 protein mutant form results in increased susceptibility to Niclosamide] which results in increased abundance of Docosahexaenoic Acids; [TP53 protein mutant form results in increased susceptibility to Niclosamide] which results in increased abundance of Eicosapentaenoic Acid; [TP53 protein mutant form results in increased susceptibility to Niclosamide] which results in increased abundance of Lysophosphatidylcholines; [TP53 protein mutant form results in increased susceptibility to Niclosamide] which results in increased abundance of lysophosphatidylethanolamine; [TP53 protein mutant form results in increased susceptibility to Niclosamide] which results in increased cleavage of PARP1 protein; [TP53 protein mutant form results in increased susceptibility to Niclosamide] which results in increased expression of CASP3 protein modified form		 CTD PMID:22576131 PMID:25988281 PMID:29031202 PMID:30258081 PMID:36318118 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tpi1 triosephosphate isomerase 1 increases expression ISO Niclosamide results in increased expression of TPI1 mRNA CTD PMID:22576131 NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541 		JBrowse link
G Tppp tubulin polymerization promoting protein increases expression ISO Niclosamide results in increased expression of TPPP mRNA CTD PMID:36318118 NCBI chr 1:29,257,111...29,281,134
Ensembl chr 1:29,261,255...29,281,134 		JBrowse link
G Tpx2 TPX2, microtubule nucleation factor decreases expression ISO Niclosamide results in decreased expression of TPX2 mRNA CTD PMID:28284560 NCBI chr 3:141,318,428...141,360,684
Ensembl chr 3:141,318,455...141,360,468 		JBrowse link
G Traf6 TNF receptor associated factor 6 multiple interactions ISO Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of TRAF6 protein] CTD PMID:28824321 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
G Trappc9 trafficking protein particle complex subunit 9 increases expression ISO Niclosamide results in increased expression of TRAPPC9 mRNA CTD PMID:36318118 NCBI chr 7:104,521,593...104,998,352
Ensembl chr 7:104,521,593...104,998,352 		JBrowse link
G Trib3 tribbles pseudokinase 3 increases expression ISO Niclosamide results in increased expression of TRIB3 mRNA CTD PMID:36318118 NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497 		JBrowse link
G Trim67 tripartite motif-containing 67 increases expression ISO Niclosamide results in increased expression of TRIM67 mRNA CTD PMID:36318118 NCBI chr19:52,763,991...52,805,906
Ensembl chr19:52,764,387...52,800,422 		JBrowse link
G Trip10 thyroid hormone receptor interactor 10 increases expression ISO Niclosamide results in increased expression of TRIP10 mRNA CTD PMID:36318118 NCBI chr 9:2,133,085...2,147,795
Ensembl chr 9:2,133,671...2,147,799 		JBrowse link
G Trip13 thyroid hormone receptor interactor 13 decreases expression ISO Niclosamide results in decreased expression of TRIP13 mRNA CTD PMID:28284560 NCBI chr 1:29,357,093...29,402,078
Ensembl chr 1:29,357,130...29,402,074 		JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 increases expression ISO Niclosamide results in increased expression of TRPM4 mRNA CTD PMID:36318118 NCBI chr 1:95,781,805...95,812,095
Ensembl chr 1:95,782,000...95,812,532 		JBrowse link
G Tsc22d3 TSC22 domain family, member 3 increases expression ISO Niclosamide results in increased expression of TSC22D3 mRNA CTD PMID:36318118 NCBI chr  X:104,217,898...104,277,886
Ensembl chr  X:104,217,925...104,276,861 		JBrowse link
G Ttc9b tetratricopeptide repeat domain 9B increases expression ISO Niclosamide results in increased expression of TTC9B mRNA CTD PMID:36318118 NCBI chr 1:82,953,434...82,955,659
Ensembl chr 1:82,953,434...82,955,616 		JBrowse link
G Ttll1 TTL family tubulin polyglutamylase complex subunit L1 increases expression ISO Niclosamide results in increased expression of TTLL1 mRNA CTD PMID:36318118 NCBI chr 7:114,619,509...114,648,850
Ensembl chr 7:114,619,508...114,648,761 		JBrowse link
G Ttll3 tubulin tyrosine ligase like 3 increases expression ISO Niclosamide results in increased expression of TTLL3 mRNA CTD PMID:36318118 NCBI chr 4:146,532,958...146,558,425
Ensembl chr 4:146,533,953...146,557,889 		JBrowse link
G Tubb1 tubulin, beta 1 class VI decreases expression ISO Niclosamide results in decreased expression of TUBB1 mRNA CTD PMID:36318118 NCBI chr 3:163,247,990...163,257,460
Ensembl chr 3:163,247,967...163,256,063 		JBrowse link
G Twist1 twist family bHLH transcription factor 1 decreases expression
increases expression		 ISO Niclosamide results in decreased expression of TWIST1 protein
Niclosamide results in increased expression of TWIST1 mRNA		 CTD PMID:29480568 PMID:36318118 NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653 		JBrowse link
G Ubald2 UBA-like domain containing 2 increases expression ISO Niclosamide results in increased expression of UBALD2 mRNA CTD PMID:36318118 NCBI chr10:101,662,507...101,667,089
Ensembl chr10:101,658,127...101,667,061 		JBrowse link
G Ube2c ubiquitin-conjugating enzyme E2C multiple interactions
decreases expression		 ISO [Niclosamide co-treated with bicalutamide] results in decreased expression of UBE2C mRNA
Niclosamide results in decreased expression of UBE2C mRNA		 CTD PMID:28500234 NCBI chr 3:153,506,636...153,509,036
Ensembl chr 3:153,506,636...153,513,339 		JBrowse link
G Uhrf1 ubiquitin-like with PHD and ring finger domains 1 decreases expression ISO Niclosamide results in decreased expression of UHRF1 mRNA CTD PMID:28284560 PMID:36318118 NCBI chr 9:1,133,117...1,154,639
Ensembl chr 9:1,134,909...1,154,631 		JBrowse link
G Unc93b1 unc-93 homolog B1, TLR signaling regulator increases expression ISO Niclosamide results in increased expression of UNC93B1 mRNA CTD PMID:36318118 NCBI chr 1:201,167,388...201,178,343
Ensembl chr 1:201,152,693...201,178,338 		JBrowse link
G Utp3 UTP3, small subunit processome component decreases expression ISO Niclosamide results in decreased expression of UTP3 mRNA CTD PMID:27226553 NCBI chr14:19,515,716...19,517,370
Ensembl chr14:19,515,669...19,517,396 		JBrowse link
G Vamp4 vesicle-associated membrane protein 4 increases expression ISO Niclosamide results in increased expression of VAMP4 mRNA CTD PMID:36318118 NCBI chr13:74,919,872...74,942,791
Ensembl chr13:74,919,880...74,933,686 		JBrowse link
G Vasn vasorin affects expression ISO Niclosamide affects the expression of VASN mRNA CTD PMID:36318118 NCBI chr10:10,917,750...10,928,259
Ensembl chr10:10,917,605...10,928,357 		JBrowse link
G Vat1 vesicle amine transport 1 increases expression ISO Niclosamide results in increased expression of VAT1 mRNA CTD PMID:36318118 NCBI chr10:86,389,549...86,397,167
Ensembl chr10:86,389,545...86,397,224 		JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression ISO Niclosamide results in decreased expression of VEGFA mRNA; Niclosamide results in decreased expression of VEGFA protein CTD PMID:29251334 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Vgf VGF nerve growth factor inducible increases expression ISO Niclosamide results in increased expression of VGF mRNA CTD PMID:36318118 NCBI chr12:19,637,313...19,645,123
Ensembl chr12:19,637,320...19,640,341 		JBrowse link
G Vim vimentin multiple interactions
decreases expression		 ISO HIPK2 protein inhibits the reaction [Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of VIM mRNA]]; Niclosamide inhibits the reaction [[Lapatinib results in decreased susceptibility to Lapatinib] which results in increased expression of VIM protein]; Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of VIM mRNA]; Niclosamide inhibits the reaction [TGFB1 protein results in increased phosphorylation of VIM protein]
Niclosamide results in decreased expression of VIM mRNA; Niclosamide results in decreased expression of VIM protein		 CTD PMID:26643609 PMID:28318631 PMID:30143678 PMID:35115509 PMID:36870549 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187 		JBrowse link
G Vpreb1a V-set pre-B cell surrogate light chain 1A decreases expression ISO Niclosamide results in decreased expression of VPREB1 mRNA CTD PMID:27226553 NCBI chr11:84,126,969...84,127,846
Ensembl chr11:84,126,969...84,127,846 		JBrowse link
G Vps37d VPS37D subunit of ESCRT-I increases expression ISO Niclosamide results in increased expression of VPS37D mRNA CTD PMID:36318118 NCBI chr12:21,609,210...21,614,669
Ensembl chr12:21,609,182...21,614,659 		JBrowse link
G Vsig10l V-set and immunoglobulin domain containing 10 like increases expression ISO Niclosamide results in increased expression of VSIG10L mRNA CTD PMID:36318118 NCBI chr 1:93,871,487...93,880,157
Ensembl chr 1:93,851,774...93,879,566 		JBrowse link
G Wipi1 WD repeat domain, phosphoinositide interacting 1 increases expression ISO Niclosamide results in increased expression of WIPI1 mRNA CTD PMID:36318118 NCBI chr10:94,542,946...94,580,174
Ensembl chr10:94,542,946...94,579,846 		JBrowse link
G Wnt1 Wnt family member 1 decreases expression ISO Niclosamide results in decreased expression of WNT1 protein CTD PMID:35115509 NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651 		JBrowse link
G Wnt10a Wnt family member 10A increases expression ISO Niclosamide results in increased expression of WNT10A mRNA CTD PMID:36318118 NCBI chr 9:76,349,931...76,362,400
Ensembl chr 9:76,349,931...76,362,400 		JBrowse link
G Wnt2b Wnt family member 2B decreases expression ISO Niclosamide results in decreased expression of WNT2B mRNA CTD PMID:22576131 NCBI chr 2:192,454,226...192,468,599
Ensembl chr 2:192,453,824...192,470,308 		JBrowse link
G Wnt3 Wnt family member 3 decreases expression ISO Niclosamide results in decreased expression of WNT3 mRNA CTD PMID:22576131 NCBI chr10:88,680,198...88,724,170
Ensembl chr10:88,680,248...88,724,099 		JBrowse link
G Wnt3a Wnt family member 3A multiple interactions
decreases expression		 ISO
EXP		 Niclosamide inhibits the reaction [WNT3A protein affects the localization of CTNNB1 protein]; Niclosamide inhibits the reaction [WNT3A protein affects the localization of RELA protein]; Niclosamide inhibits the reaction [WNT3A protein results in increased stability of CTNNB1 protein]
Niclosamide results in decreased expression of WNT3A mRNA
Niclosamide inhibits the reaction [Thioacetamide results in increased expression of WNT3A mRNA]; Poloxamer promotes the reaction [Niclosamide inhibits the reaction [Thioacetamide results in increased expression of WNT3A mRNA]]		 CTD PMID:19772353 PMID:22576131 PMID:27492973 PMID:32961231 NCBI chr10:44,034,174...44,078,366
Ensembl chr10:44,034,194...44,078,324 		JBrowse link
G Wnt7a Wnt family member 7A increases response to substance
decreases activity
multiple interactions		 ISO WNT7A protein results in increased susceptibility to Niclosamide
Niclosamide results in decreased activity of WNT7A protein
WNT7A protein affects the reaction [Niclosamide results in increased cleavage of CASP3 protein]; WNT7A protein affects the reaction [Niclosamide results in increased cleavage of PARP1 protein]; WNT7A protein affects the reaction [Niclosamide results in increased expression of CDH1 protein]; WNT7A protein affects the reaction [Niclosamide results in increased expression of SNAI2 protein]		 CTD PMID:25174399 NCBI chr 4:123,863,108...123,908,981
Ensembl chr 4:123,863,108...123,908,981 		JBrowse link
G Wnt8b Wnt family member 8B increases expression ISO Niclosamide results in increased expression of WNT8B mRNA CTD PMID:36318118 NCBI chr 1:243,354,145...243,376,000
Ensembl chr 1:243,354,086...243,374,286 		JBrowse link
G Wtip WT1 interacting protein increases expression ISO Niclosamide results in increased expression of WTIP mRNA CTD PMID:36318118 NCBI chr 1:86,731,214...86,764,939
Ensembl chr 1:86,731,265...86,765,014 		JBrowse link
G Xiap X-linked inhibitor of apoptosis decreases expression ISO Niclosamide results in decreased expression of XIAP protein CTD PMID:20215516 NCBI chr  X:120,890,537...120,938,413
Ensembl chr  X:120,897,907...120,934,700 		JBrowse link
G Xndc1 Xrcc1 N-terminal domain containing 1 decreases expression ISO Niclosamide results in decreased expression of XNDC1N mRNA CTD PMID:36318118 NCBI chr 1:156,440,284...156,460,609 JBrowse link
G Ypel1 yippee-like 1 increases expression ISO Niclosamide results in increased expression of YPEL1 mRNA CTD PMID:36318118 NCBI chr11:83,921,799...83,936,409 JBrowse link
G Ypel5 yippee-like 5 increases expression ISO Niclosamide results in increased expression of YPEL5 mRNA CTD PMID:36318118 NCBI chr 6:22,656,284...22,671,741
Ensembl chr 6:22,656,285...22,671,691 		JBrowse link
G Zbtb22 zinc finger and BTB domain containing 22 increases expression ISO Niclosamide results in increased expression of ZBTB22 mRNA CTD PMID:36318118 NCBI chr20:4,966,331...4,969,853
Ensembl chr20:4,966,271...4,969,498 		JBrowse link
G Zbtb41 zinc finger and BTB domain containing 41 increases expression ISO Niclosamide results in increased expression of ZBTB41 mRNA CTD PMID:36318118 NCBI chr13:51,042,948...51,065,768
Ensembl chr13:51,042,948...51,065,768 		JBrowse link
G Zbtb46 zinc finger and BTB domain containing 46 increases expression ISO Niclosamide results in increased expression of ZBTB46 mRNA CTD PMID:36318118 NCBI chr 3:168,497,294...168,567,799
Ensembl chr 3:168,499,583...168,568,782 		JBrowse link
G Zbtb7b zinc finger and BTB domain containing 7B increases expression ISO Niclosamide results in increased expression of ZBTB7B mRNA CTD PMID:36318118 NCBI chr 2:174,795,831...174,811,980
Ensembl chr 2:174,797,453...174,814,236 		JBrowse link
G Zfp157 zinc finger protein 157 increases expression ISO Niclosamide results in increased expression of ZNF157 mRNA CTD PMID:36318118 NCBI chr12:16,248,230...16,279,459
Ensembl chr12:16,248,230...16,270,698 		JBrowse link
G Zfp18 zinc finger protein 18 increases expression ISO Niclosamide results in increased expression of ZNF18 mRNA CTD PMID:36318118 NCBI chr10:50,473,428...50,495,707
Ensembl chr10:50,473,483...50,495,706 		JBrowse link
G Zfp277 zinc finger protein 277 increases expression ISO Niclosamide results in increased expression of ZNF277 mRNA CTD PMID:36318118 NCBI chr 6:57,383,454...57,512,785
Ensembl chr 6:57,383,951...57,512,765 		JBrowse link
G Zfp296 zinc finger protein 296 increases expression ISO Niclosamide results in increased expression of ZNF296 mRNA CTD PMID:36318118 NCBI chr 1:79,228,649...79,231,866
Ensembl chr 1:79,228,401...79,231,866 		JBrowse link
G Zfp36 zinc finger protein 36 increases expression ISO Niclosamide results in increased expression of ZFP36 mRNA CTD PMID:28284560 NCBI chr 1:83,669,084...83,671,564
Ensembl chr 1:83,669,084...83,671,564 		JBrowse link
G Zfp367 zinc finger protein 367 decreases expression ISO Niclosamide results in decreased expression of ZNF367 mRNA CTD PMID:36318118 NCBI chr17:965,161...984,290
Ensembl chr17:965,161...984,287 		JBrowse link
G Zfp458 zinc finger protein 458 decreases expression ISO Niclosamide results in decreased expression of ZNF43 mRNA CTD PMID:36318118 NCBI chr 2:84,661,150...84,705,631
Ensembl chr 2:84,693,186...84,702,558 		JBrowse link
G Zfp467 zinc finger protein 467 increases expression ISO Niclosamide results in increased expression of ZNF467 mRNA CTD PMID:36318118 NCBI chr 4:77,385,752...77,394,709
Ensembl chr 4:77,385,758...77,392,229 		JBrowse link
G Zfp551 zinc finger protein 551 decreases expression ISO Niclosamide results in decreased expression of ZNF551 mRNA CTD PMID:36318118 NCBI chr 1:72,543,815...72,554,060
Ensembl chr 1:72,540,108...72,554,071 		JBrowse link
G Zfp703 zinc finger protein 703 decreases expression ISO Niclosamide results in decreased expression of ZNF703 mRNA CTD PMID:36318118 NCBI chr16:65,076,507...65,080,677
Ensembl chr16:65,076,507...65,080,677 		JBrowse link
G Zfp853 zinc finger protein 853 increases expression ISO Niclosamide results in increased expression of ZNF853 mRNA CTD PMID:36318118 NCBI chr12:11,266,124...11,276,492
Ensembl chr12:11,269,414...11,275,731 		JBrowse link
G Zfp862 zinc finger protein 862 increases expression ISO Niclosamide results in increased expression of ZNF862 mRNA CTD PMID:36318118 NCBI chr 4:77,452,930...77,481,981
Ensembl chr 4:77,453,037...77,481,995 		JBrowse link
G Zfp9 zinc finger protein 9 increases expression ISO Niclosamide results in increased expression of ZNF25 mRNA CTD PMID:36318118 NCBI chr 4:151,638,724...151,656,740
Ensembl chr 4:151,638,711...151,656,803 		JBrowse link
G Zhx3 zinc fingers and homeoboxes 3 increases expression ISO Niclosamide results in increased expression of ZHX3 mRNA CTD PMID:36318118 NCBI chr 3:149,417,787...149,548,671
Ensembl chr 3:149,417,818...149,527,079 		JBrowse link
G Zic2 Zic family member 2 increases expression ISO Niclosamide results in increased expression of ZIC2 mRNA CTD PMID:28284560 NCBI chr15:99,576,697...99,581,522
Ensembl chr15:99,576,697...99,581,522 		JBrowse link
G Zswim4 zinc finger, SWIM-type containing 4 increases expression ISO Niclosamide results in increased expression of ZSWIM4 mRNA CTD PMID:36318118 NCBI chr19:23,927,845...23,952,970
Ensembl chr19:23,927,845...23,952,970 		JBrowse link
G Zwint ZW10 interacting kinetochore protein decreases expression ISO Niclosamide results in decreased expression of ZWINT mRNA CTD PMID:36318118 NCBI chr20:15,938,157...15,953,997
Ensembl chr20:15,938,157...15,953,957 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19838
    role 19814
      application 19658
        pesticide 17924
          piscicide 4942
            niclosamide 871
Path 2
Term Annotations click to browse term
  CHEBI ontology 19838
    subatomic particle 19836
      composite particle 19836
        hadron 19836
          baryon 19836
            nucleon 19836
              atomic nucleus 19836
                atom 19836
                  main group element atom 19786
                    p-block element atom 19786
                      carbon group element atom 19734
                        carbon atom 19731
                          organic molecular entity 19731
                            heteroorganic entity 19488
                              organochalcogen compound 19251
                                organooxygen compound 19168
                                  carbon oxoacid 18637
                                    carboxylic acid 18634
                                      carboacyl group 17696
                                        univalent carboacyl group 17696
                                          carbamoyl group 17546
                                            carboxamide 17546
                                              monocarboxylic acid amide 15681
                                                arenecarboxamide 8249
                                                  benzamides 8249
                                                    salicylamides 910
                                                      salicylamide 884
                                                        salicylanilides 874
                                                          niclosamide 871
paths to the root