Gene: Ctsk (cathepsin K) Rattus norvegicus
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Symbol: Ctsk
Name: cathepsin K
Description: ENCODES a protein that exhibits collagen binding (ortholog); cysteine-type endopeptidase activity (ortholog); fibronectin binding (ortholog); INVOLVED IN bone resorption; intramembranous ossification; collagen catabolic process (ortholog); PARTICIPATES IN rheumatoid arthritis disease pathway; Toll-like receptor signaling pathway; ASSOCIATED WITH Arthritis, Experimental; Intracranial Aneurysm; intracranial aneurysm; FOUND IN cytoplasm; extracellular space; lysosome; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; (S)-amphetamine; 1,2,4-trimethylbenzene
Type: protein-coding
RefSeq Status: PROVISIONAL
Orthologs:
Homo sapiens (human) : CTSK (cathepsin K)  HGNC  AGR
Mus musculus (house mouse) : Ctsk (cathepsin K)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Ctsk (cathepsin K)
Pan paniscus (bonobo/pygmy chimpanzee) : CTSK (cathepsin K)
Canis lupus familiaris (dog) : CTSK (cathepsin K)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ctsk (cathepsin K)
more info ...
Is Marker For: QTLs:   Bp364  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02196,655,469 - 196,666,447 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02216,154,168 - 216,164,779 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42190,394,854 - 190,405,668 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12190,357,607 - 190,368,421 (+)NCBI
Celera2175,591,773 - 175,602,552 (+)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Ctsk
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 61810
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE