1,1-dichloroethene decreases expression ISO Ppp2r2b (Mus musculus) 6480464 vinylidene chloride results in decreased expression of PPP2R2B mRNA CTD PMID:26682919 1,2-dimethylhydrazine decreases expression ISO Ppp2r2b (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in decreased expression of PPP2R2B mRNA CTD PMID:22206623 17alpha-ethynylestradiol decreases expression EXP 6480464 Ethinyl Estradiol results in decreased expression of PPP2R2B mRNA CTD PMID:15834898 and PMID:17557909 17beta-estradiol increases expression ISO Ppp2r2b (Mus musculus) 6480464 Estradiol results in increased expression of PPP2R2B mRNA CTD PMID:19484750 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of PPP2R2B mRNA CTD PMID:35192832 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of PPP2R2B mRNA CTD PMID:32145629 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions EXP 6480464 [3 more ... CTD PMID:16984957 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Ppp2r2b (Mus musculus) 6480464 [2 more ... CTD PMID:25510870 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO Ppp2r2b (Mus musculus) 6480464 [2 more ... CTD PMID:25510870 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Ppp2r2b (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of PPP2R2B mRNA CTD PMID:19933214 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of PPP2R2B mRNA CTD PMID:22298810 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Ppp2r2b (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of PPP2R2B mRNA CTD PMID:16922920 2,6-dinitrotoluene affects expression EXP 6480464 2 and 6-dinitrotoluene affects the expression of PPP2R2B mRNA CTD PMID:21346803 2-nitrotoluene increases expression EXP 6480464 2-nitrotoluene results in increased expression of PPP2R2B mRNA CTD PMID:16460773 3,3',4,4',5-pentachlorobiphenyl multiple interactions EXP 6480464 [3 more ... CTD PMID:16984957 3,3',4,4',5-pentachlorobiphenyl decreases expression EXP 6480464 3 more ... CTD PMID:23196670 4,4'-sulfonyldiphenol multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of PPP2R2B mRNA CTD PMID:36041667 5-aza-2'-deoxycytidine affects expression ISO PPP2R2B (Homo sapiens) 6480464 Decitabine affects the expression of PPP2R2B mRNA CTD PMID:23300844 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of PPP2R2B mRNA CTD PMID:24780913 7,12-dimethyltetraphene increases expression EXP 6480464 9 more ... CTD PMID:19480007 aconitine increases expression EXP 6480464 Aconitine results in increased expression of PPP2R2B protein CTD PMID:33236894 aflatoxin B1 decreases expression ISO PPP2R2B (Homo sapiens) 6480464 Aflatoxin B1 results in decreased expression of PPP2R2B mRNA CTD PMID:22100608 aflatoxin B1 affects methylation ISO PPP2R2B (Homo sapiens) 6480464 Aflatoxin B1 affects the methylation of PPP2R2B intron CTD PMID:30157460 aflatoxin B1 decreases methylation ISO PPP2R2B (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of PPP2R2B gene CTD PMID:27153756 Aflatoxin B2 alpha increases methylation ISO PPP2R2B (Homo sapiens) 6480464 aflatoxin B2 results in increased methylation of PPP2R2B intron CTD PMID:30157460 aflatoxin M1 decreases expression ISO PPP2R2B (Homo sapiens) 6480464 Aflatoxin M1 results in decreased expression of PPP2R2B mRNA CTD PMID:30928695 all-trans-retinoic acid increases expression ISO PPP2R2B (Homo sapiens) 6480464 Tretinoin results in increased expression of PPP2R2B mRNA CTD PMID:16249480 and PMID:23724009 alpha-hexachlorocyclohexane decreases expression EXP 6480464 alpha-hexachlorocyclohexane results in decreased expression of PPP2R2B mRNA CTD PMID:17785943 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of PPP2R2B mRNA CTD PMID:16483693 arsane multiple interactions ISO PPP2R2B (Homo sapiens) 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of PPP2R2B mRNA CTD PMID:32525701 arsenic atom multiple interactions ISO PPP2R2B (Homo sapiens) 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of PPP2R2B mRNA CTD PMID:32525701 atrazine affects methylation EXP 6480464 Atrazine affects the methylation of PPP2R2B gene CTD PMID:28931070 and PMID:35440735 benzo[a]pyrene decreases methylation ISO Ppp2r2b (Mus musculus) 6480464 Benzo(a)pyrene results in decreased methylation of PPP2R2B intron CTD PMID:27901495 benzo[a]pyrene decreases expression ISO PPP2R2B (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of PPP2R2B mRNA CTD PMID:32234424 benzo[a]pyrene affects methylation ISO PPP2R2B (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of PPP2R2B 5' UTR more ... CTD PMID:27901495 and PMID:30157460 benzo[a]pyrene diol epoxide I decreases expression ISO PPP2R2B (Homo sapiens) 6480464 7 more ... CTD PMID:19150397 benzo[e]pyrene increases methylation ISO PPP2R2B (Homo sapiens) 6480464 benzo(e)pyrene results in increased methylation of PPP2R2B intron CTD PMID:30157460 bis(2-ethylhexyl) phthalate multiple interactions EXP 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of PPP2R2B mRNA CTD PMID:31199487 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of PPP2R2B mRNA CTD PMID:25181051 and PMID:32145629 bisphenol A increases expression ISO Ppp2r2b (Mus musculus) 6480464 bisphenol A results in increased expression of PPP2R2B mRNA CTD PMID:32156529 bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of PPP2R2B mRNA CTD PMID:36041667 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of PPP2R2B mRNA CTD PMID:35192832 bisphenol A increases methylation ISO PPP2R2B (Homo sapiens) 6480464 bisphenol A results in increased methylation of PPP2R2B gene CTD PMID:31601247 bisphenol A multiple interactions ISO PPP2R2B (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] affects the methylation of PPP2R2B gene CTD PMID:31601247 bisphenol A decreases expression ISO Ppp2r2b (Mus musculus) 6480464 bisphenol A results in decreased expression of PPP2R2B mRNA CTD PMID:30951980 bisphenol F decreases expression ISO Ppp2r2b (Mus musculus) 6480464 bisphenol F results in decreased expression of PPP2R2B mRNA CTD PMID:30951980 bisphenol F multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of PPP2R2B mRNA CTD PMID:36041667 bleomycin A5 increases expression ISO PPP2R2B (Homo sapiens) 6480464 bleomycetin results in increased expression of PPP2R2B mRNA CTD PMID:21040473 bromochloroacetic acid increases expression EXP 6480464 bromochloroacetic acid results in increased expression of PPP2R2B mRNA CTD PMID:16460773 butanal increases expression ISO PPP2R2B (Homo sapiens) 6480464 butyraldehyde results in increased expression of PPP2R2B mRNA CTD PMID:26079696 Butylbenzyl phthalate multiple interactions EXP 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of PPP2R2B mRNA CTD PMID:31199487 caffeine decreases expression ISO PPP2R2B (Homo sapiens) 6480464 Caffeine results in decreased expression of PPP2R2B mRNA CTD PMID:18444173 carbon nanotube decreases expression ISO Ppp2r2b (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25554681 CGP 52608 multiple interactions ISO PPP2R2B (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to PPP2R2B gene] CTD PMID:28238834 cisplatin affects expression ISO PPP2R2B (Homo sapiens) 6480464 Cisplatin affects the expression of PPP2R2B mRNA CTD PMID:23300844 cisplatin increases expression ISO PPP2R2B (Homo sapiens) 6480464 Cisplatin results in increased expression of PPP2R2B mRNA CTD PMID:27392435 cocaine affects expression EXP 6480464 Cocaine affects the expression of PPP2R2B mRNA CTD PMID:20187946 copper atom multiple interactions ISO PPP2R2B (Homo sapiens) 6480464 [Chelating Agents binds to Copper] which results in increased expression of PPP2R2B mRNA and [Disulfiram binds to Copper] which results in decreased expression of PPP2R2B mRNA CTD PMID:24690739 and PMID:30911355 copper atom increases expression EXP 6480464 Copper results in increased expression of PPP2R2B mRNA CTD PMID:30556269 copper(0) multiple interactions ISO PPP2R2B (Homo sapiens) 6480464 [Chelating Agents binds to Copper] which results in increased expression of PPP2R2B mRNA and [Disulfiram binds to Copper] which results in decreased expression of PPP2R2B mRNA CTD PMID:24690739 and PMID:30911355 copper(0) increases expression EXP 6480464 Copper results in increased expression of PPP2R2B mRNA CTD PMID:30556269 corticosterone decreases expression EXP 6480464 Corticosterone results in decreased expression of PPP2R2B mRNA CTD PMID:15755911 DDT increases methylation EXP 6480464 DDT results in increased methylation of PPP2R2B gene CTD PMID:30207508 and PMID:31682807 decabromodiphenyl ether multiple interactions EXP 6480464 [Flame Retardants co-treated with pentabromodiphenyl ether co-treated with decabromobiphenyl ether co-treated with hexabromocyclododecane] results in decreased expression of PPP2R2B mRNA CTD PMID:32207525 dibutyl phthalate multiple interactions EXP 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of PPP2R2B mRNA CTD PMID:31199487 diethyl phthalate multiple interactions EXP 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of PPP2R2B mRNA CTD PMID:31199487 diethylstilbestrol decreases expression EXP 6480464 Diethylstilbestrol results in decreased expression of PPP2R2B mRNA CTD PMID:17005392 diethylstilbestrol increases expression EXP 6480464 Diethylstilbestrol results in increased expression of PPP2R2B mRNA CTD PMID:37077353 diisobutyl phthalate multiple interactions EXP 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of PPP2R2B mRNA CTD PMID:31199487 diisononyl phthalate multiple interactions EXP 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of PPP2R2B mRNA CTD PMID:31199487 disulfiram multiple interactions ISO PPP2R2B (Homo sapiens) 6480464 [Disulfiram binds to Copper] which results in decreased expression of PPP2R2B mRNA CTD PMID:24690739 diuron decreases expression EXP 6480464 Diuron results in decreased expression of PPP2R2B mRNA CTD PMID:21551480 dorsomorphin multiple interactions ISO PPP2R2B (Homo sapiens) 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxorubicin decreases expression ISO PPP2R2B (Homo sapiens) 6480464 Doxorubicin results in decreased expression of PPP2R2B mRNA CTD PMID:29803840 ethanol multiple interactions ISO Ppp2r2b (Mus musculus) 6480464 Ethanol affects the expression of and affects the splicing of PPP2R2B mRNA CTD PMID:30319688 folic acid decreases expression ISO Ppp2r2b (Mus musculus) 6480464 Folic Acid results in decreased expression of PPP2R2B mRNA CTD PMID:25629700 fulvestrant multiple interactions ISO PPP2R2B (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] affects the methylation of PPP2R2B gene CTD PMID:31601247 gamma-hexachlorocyclohexane decreases expression EXP 6480464 Hexachlorocyclohexane results in decreased expression of PPP2R2B mRNA CTD PMID:17785943 genistein increases expression ISO PPP2R2B (Homo sapiens) 6480464 Genistein results in increased expression of PPP2R2B mRNA CTD PMID:18444173 gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of PPP2R2B mRNA CTD PMID:33387578 GW 4064 decreases expression ISO Ppp2r2b (Mus musculus) 6480464 GW 4064 results in decreased expression of PPP2R2B mRNA CTD PMID:26655953 inulin multiple interactions ISO Ppp2r2b (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of PPP2R2B mRNA CTD PMID:36331819 ketoconazole increases expression EXP 6480464 Ketoconazole results in increased expression of PPP2R2B mRNA CTD PMID:37077353 Lasiocarpine decreases expression ISO PPP2R2B (Homo sapiens) 6480464 lasiocarpine results in decreased expression of PPP2R2B mRNA CTD PMID:32234424 lead(0) affects expression ISO PPP2R2B (Homo sapiens) 6480464 Lead affects the expression of PPP2R2B mRNA CTD PMID:28903495 LY294002 multiple interactions ISO PPP2R2B (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of PPP2R2B mRNA] CTD PMID:12710931 melphalan decreases expression ISO PPP2R2B (Homo sapiens) 6480464 Melphalan results in decreased expression of PPP2R2B mRNA CTD PMID:22363485 mercury dibromide decreases expression ISO PPP2R2B (Homo sapiens) 6480464 mercuric bromide results in decreased expression of PPP2R2B mRNA CTD PMID:26272509 mercury dibromide multiple interactions ISO PPP2R2B (Homo sapiens) 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PPP2R2B mRNA CTD PMID:27188386 methapyrilene increases methylation ISO PPP2R2B (Homo sapiens) 6480464 Methapyrilene results in increased methylation of PPP2R2B intron CTD PMID:30157460 methoxychlor affects methylation EXP 6480464 Methoxychlor affects the methylation of PPP2R2B gene CTD PMID:35440735 methylmercury chloride decreases expression ISO PPP2R2B (Homo sapiens) 6480464 methylmercuric chloride results in decreased expression of PPP2R2B mRNA CTD PMID:23179753 more ... mono(2-ethylhexyl) phthalate decreases expression ISO PPP2R2B (Homo sapiens) 6480464 mono-(2-ethylhexyl)phthalate results in decreased expression of PPP2R2B mRNA CTD PMID:36695872 N-methyl-4-phenylpyridinium multiple interactions ISO PPP2R2B (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of PPP2R2B mRNA] CTD PMID:12710931 nevirapine decreases expression EXP 6480464 Nevirapine metabolite results in decreased expression of PPP2R2B mRNA and Nevirapine results in decreased expression of PPP2R2B mRNA CTD PMID:23947594 niclosamide decreases expression ISO PPP2R2B (Homo sapiens) 6480464 Niclosamide results in decreased expression of PPP2R2B mRNA CTD PMID:22576131 Nor-9-carboxy-delta9-THC multiple interactions ISO PPP2R2B (Homo sapiens) 6480464 [Cannabinoids results in increased abundance of 11-nor-delta(9)-tetrahydrocannabinol-9-carboxylic acid] which affects the methylation of PPP2R2B gene CTD PMID:30521419 O-methyleugenol decreases expression ISO PPP2R2B (Homo sapiens) 6480464 methyleugenol results in decreased expression of PPP2R2B mRNA CTD PMID:32234424 p-chloromercuribenzoic acid decreases expression ISO PPP2R2B (Homo sapiens) 6480464 p-Chloromercuribenzoic Acid results in decreased expression of PPP2R2B mRNA CTD PMID:26272509 p-chloromercuribenzoic acid multiple interactions ISO PPP2R2B (Homo sapiens) 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PPP2R2B mRNA CTD PMID:27188386 panobinostat multiple interactions ISO PPP2R2B (Homo sapiens) 6480464 [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PPP2R2B mRNA CTD PMID:27188386 panobinostat decreases expression ISO PPP2R2B (Homo sapiens) 6480464 panobinostat results in decreased expression of PPP2R2B mRNA CTD PMID:26272509 PCB138 multiple interactions ISO Ppp2r2b (Mus musculus) 6480464 [2 more ... CTD PMID:25510870 pentanal increases expression ISO PPP2R2B (Homo sapiens) 6480464 pentanal results in increased expression of PPP2R2B mRNA CTD PMID:26079696 perfluorooctane-1-sulfonic acid multiple interactions ISO Ppp2r2b (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of PPP2R2B mRNA CTD PMID:36331819 phenylmercury acetate decreases expression ISO PPP2R2B (Homo sapiens) 6480464 Phenylmercuric Acetate results in decreased expression of PPP2R2B mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO PPP2R2B (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PPP2R2B mRNA CTD PMID:27188386 pioglitazone increases expression ISO PPP2R2B (Homo sapiens) 6480464 Pioglitazone results in increased expression of PPP2R2B mRNA CTD PMID:32589349 potassium chromate increases expression ISO PPP2R2B (Homo sapiens) 6480464 potassium chromate(VI) results in increased expression of PPP2R2B mRNA CTD PMID:22714537 pregnenolone 16alpha-carbonitrile decreases expression EXP 6480464 Pregnenolone Carbonitrile results in decreased expression of PPP2R2B mRNA CTD PMID:19162173 progesterone affects expression ISO Ppp2r2b (Mus musculus) 6480464 Progesterone affects the expression of PPP2R2B mRNA CTD PMID:17251523 progesterone decreases expression ISO Ppp2r2b (Mus musculus) 6480464 Progesterone results in decreased expression of PPP2R2B mRNA CTD PMID:17556502 and PMID:22238285 rotenone affects localization EXP 6480464 Rotenone affects the localization of PPP2R2B protein CTD PMID:18940801 rotenone increases expression EXP 6480464 Rotenone results in increased expression of PPP2R2B mRNA CTD PMID:28374803 rotenone decreases expression ISO Ppp2r2b (Mus musculus) 6480464 Rotenone results in decreased expression of PPP2R2B mRNA CTD PMID:23186747 SB 431542 multiple interactions ISO PPP2R2B (Homo sapiens) 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 sodium arsenate multiple interactions ISO PPP2R2B (Homo sapiens) 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of PPP2R2B mRNA CTD PMID:32525701 sodium fluoride decreases expression ISO Ppp2r2b (Mus musculus) 6480464 Sodium Fluoride results in decreased expression of PPP2R2B mRNA CTD PMID:21340527 sodium fluoride increases expression EXP 6480464 Sodium Fluoride results in increased expression of PPP2R2B mRNA CTD PMID:27257137 staurosporine affects localization EXP 6480464 Staurosporine affects the localization of PPP2R2B protein CTD PMID:18940801 sulforaphane decreases expression ISO PPP2R2B (Homo sapiens) 6480464 sulforaphane results in decreased expression of PPP2R2B mRNA CTD PMID:31838189 temozolomide increases expression ISO PPP2R2B (Homo sapiens) 6480464 Temozolomide results in increased expression of PPP2R2B mRNA CTD PMID:31758290 triadimefon increases expression ISO PPP2R2B (Homo sapiens) 6480464 triadimefon results in increased expression of PPP2R2B mRNA CTD PMID:26705709 trichostatin A decreases expression ISO PPP2R2B (Homo sapiens) 6480464 trichostatin A results in decreased expression of PPP2R2B mRNA CTD PMID:26272509 trichostatin A multiple interactions ISO PPP2R2B (Homo sapiens) 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PPP2R2B mRNA CTD PMID:27188386 triphenyl phosphate affects expression EXP 6480464 triphenyl phosphate affects the expression of PPP2R2B mRNA CTD PMID:30589522 tunicamycin affects localization EXP 6480464 Tunicamycin affects the localization of PPP2R2B protein CTD PMID:18940801 valproic acid increases expression ISO PPP2R2B (Homo sapiens) 6480464 Valproic Acid results in increased expression of PPP2R2B mRNA CTD PMID:23179753 more ... vinclozolin increases methylation EXP 6480464 vinclozolin results in increased methylation of PPP2R2B gene CTD PMID:31079544 zoledronic acid affects expression ISO PPP2R2B (Homo sapiens) 6480464 zoledronic acid affects the expression of PPP2R2B mRNA CTD PMID:24714768