| (R)-adrenaline | increases activity | EXP | | 6480464 | Epinephrine results in increased activity of ADRA2A protein | CTD | PMID:17341653 |
| (R)-adrenaline | multiple interactions | ISO | RGD:737381 | 6480464 | Epinephrine inhibits the reaction [ADRA2A protein binds to 2-methoxyidazoxan]; more ... | CTD | PMID:20030735 |
| (R)-noradrenaline | multiple interactions | ISO | RGD:737381 | 6480464 | 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Norepinephrine binds to and results in increased activity of ADRA2A protein]; more ... | CTD | PMID:10742289 |
| (R)-noradrenaline | multiple interactions | ISO | RGD:10098 | 6480464 | [ADRA2A protein mutant form co-treated with ADRA2C protein mutant form] results in increased abundance of Norepinephrine | CTD | PMID:20083574 |
| (R)-noradrenaline | affects abundance | ISO | RGD:10098 | 6480464 | ADRA2A protein affects the abundance of Norepinephrine | CTD | PMID:20083574 |
| (R)-noradrenaline | multiple interactions | ISO | RGD:737381 | 6480464 | [Norepinephrine binds to and results in increased activity of ADRA2A protein] which results in increased abundance of Calcium; more ... | CTD | PMID:20030735 |
| (R)-noradrenaline | multiple interactions | ISO | RGD:737381 | 6480464 | Norepinephrine binds to and results in increased activity of ADRA2A protein | CTD | PMID:10742289 PMID:20030735 |
| (R)-noradrenaline | affects binding | ISO | RGD:10098 | 6480464 | Norepinephrine binds to ADRA2A protein | CTD | PMID:10336518 |
| (R)-noradrenaline | multiple interactions | EXP | | 6480464 | [BRL 44408 binds to and results in decreased activity of ADRA2A protein] inhibits the reaction [Xylazine inhibits the reaction [Potassium results in increased secretion of Norepinephrine]] | CTD | PMID:11312645 |
| (R)-noradrenaline | affects secretion | EXP | | 6480464 | ADRA2A protein affects the secretion of Norepinephrine | CTD | PMID:11312645 |
| 17beta-estradiol | increases expression | ISO | RGD:10098 | 6480464 | Estradiol results in increased expression of ADRA2A mRNA | CTD | PMID:15713686 |
| 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ADRA2A mRNA | CTD | PMID:21724226 |
| 2-methoxyidazoxan | affects binding | ISO | RGD:737381 | 6480464 | ADRA2A protein binds to 2-methoxyidazoxan | CTD | PMID:20030735 |
| 2-methoxyidazoxan | multiple interactions | ISO | RGD:737381 | 6480464 | Oxymetazoline inhibits the reaction [ADRA2A protein binds to 2-methoxyidazoxan]; more ... | CTD | PMID:20030735 |
| 3-methylcholanthrene | multiple interactions | ISO | RGD:737381 | 6480464 | Methylcholanthrene promotes the reaction [AHR protein binds to ADRA2A promoter] | CTD | PMID:20348232 |
| 5-aza-2'-deoxycytidine | affects expression | ISO | RGD:737381 | 6480464 | decitabine affects the expression of ADRA2A mRNA | CTD | PMID:17145863 |
| 5-aza-2'-deoxycytidine | increases expression | ISO | RGD:737381 | 6480464 | decitabine results in increased expression of ADRA2A mRNA | CTD | PMID:19194470 |
| 8-bromo-3',5'-cyclic AMP | decreases expression | ISO | RGD:737381 | 6480464 | 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ADRA2A mRNA | CTD | PMID:22079614 |
| aflatoxin B1 | decreases expression | ISO | RGD:10098 | 6480464 | Aflatoxin B1 results in decreased expression of ADRA2A mRNA | CTD | PMID:19770486 |
| all-trans-retinoic acid | increases expression | ISO | RGD:737381 | 6480464 | Tretinoin results in increased expression of ADRA2A mRNA | CTD | PMID:21934132 |
| amiodarone | increases expression | ISO | RGD:737381 | 6480464 | Amiodarone results in increased expression of ADRA2A mRNA | CTD | PMID:19774075 |
| amitraz | multiple interactions | EXP | | 6480464 | [Idazoxan binds to and results in decreased activity of ADRA2A protein] which results in decreased susceptibility to amitraz; more ... | CTD | PMID:10582558 |
| amitraz | decreases activity | ISO | RGD:737381 | 6480464 | amitraz results in decreased activity of ADRA2A protein | CTD | PMID:21251949 |
| atenolol | affects response to substance | ISO | RGD:737381 | 6480464 | ADRA2A gene SNP affects the susceptibility to Atenolol | CTD | PMID:15614026 |
| atrazine | affects activity | EXP | | 6480464 | Atrazine affects the activity of ADRA2A protein | CTD | PMID:11071396 |
| atrazine | affects binding | EXP | | 6480464 | Atrazine binds to ADRA2A protein | CTD | PMID:11071396 |
| benzo[a]pyrene | decreases expression | ISO | RGD:10098 | 6480464 | Benzo(a)pyrene results in decreased expression of ADRA2A mRNA | CTD | PMID:19770486 |
| benzo[a]pyrene | multiple interactions | ISO | RGD:10098 | 6480464 | Benzo(a)pyrene promotes the reaction [AHR protein binds to ADRA2A promoter] | CTD | PMID:19654925 |
| brimonidine | multiple interactions | ISO | RGD:737381 | 6480464 | Prazosin inhibits the reaction [Phenylephrine promotes the reaction [brimonidine binds to and results in increased activity of ADRA2A protein]]; more ... | CTD | PMID:10742289 |
| brimonidine | multiple interactions | EXP | | 6480464 | brimonidine binds to and results in increased activity of ADRA2A protein | CTD | PMID:12208771 PMID:8397342 |
| brimonidine | multiple interactions | EXP | | 6480464 | brimonidine binds to and results in increased activity of ADRA2A protein | CTD | PMID:8397342 PMID:12208771 |
| brimonidine | multiple interactions | EXP | | 6480464 | brimonidine binds to and results in increased activity of ADRA2A protein | CTD | PMID:12208771 |
| brimonidine | multiple interactions | ISO | RGD:10098 | 6480464 | brimonidine binds to and results in increased activity of ADRA2A protein | CTD | PMID:12598592 |
| C60 fullerene | decreases expression | EXP | | 6480464 | fullerene C60 results in decreased expression of ADRA2A mRNA | CTD | PMID:19167457 |
| calcium atom | multiple interactions | ISO | RGD:737381 | 6480464 | [Epinephrine binds to and results in increased activity of ADRA2A protein] which results in increased abundance of Calcium; more ... | CTD | PMID:20030735 |
| calcium(0) | multiple interactions | ISO | RGD:737381 | 6480464 | [Epinephrine binds to and results in increased activity of ADRA2A protein] which results in increased abundance of Calcium; more ... | CTD | PMID:20030735 |
| capsaicin | decreases response to substance | ISO | RGD:10098 | 6480464 | ADRA2A results in decreased susceptibility to Capsaicin | CTD | PMID:15220790 |
| chlorpyrifos | increases expression | EXP | | 6480464 | Chlorpyrifos results in increased expression of ADRA2A mRNA | CTD | PMID:18812211 |
| chlorpyrifos | affects expression | EXP | | 6480464 | Chlorpyrifos affects the expression of ADRA2A mRNA | CTD | PMID:17452286 |
| choline | multiple interactions | ISO | RGD:10098 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ADRA2A gene | CTD | PMID:20938992 |
| clonidine | multiple interactions | ISO | RGD:737381 | 6480464 | Clonidine binds to and results in increased activity of ADRA2A protein | CTD | PMID:10217548 |
| clonidine | multiple interactions | EXP | | 6480464 | [5-amino-7-(2-phenylethyl)-2-(2-furyl)pyrazolo(4,3-e)-1,2,4-triazolo(1,5-c)pyrimidine results in decreased activity of ADRA2A protein] which results in decreased susceptibility to Clonidine | CTD | PMID:17934014 PMID:16595736 |
| clonidine | multiple interactions | ISO | RGD:10098 | 6480464 | Clonidine binds to and results in increased activity of ADRA2A protein | CTD | PMID:12598592 PMID:12560108 |
| clonidine | multiple interactions | EXP | | 6480464 | [5-amino-7-(2-phenylethyl)-2-(2-furyl)pyrazolo(4,3-e)-1,2,4-triazolo(1,5-c)pyrimidine results in decreased activity of ADRA2A protein] which results in decreased susceptibility to Clonidine | CTD | PMID:16595736 PMID:17934014 |
| clonidine | multiple interactions | ISO | RGD:10098 | 6480464 | Clonidine binds to and results in increased activity of ADRA2A protein | CTD | PMID:12560108 PMID:12598592 |
| clonidine (amino form) | multiple interactions | ISO | RGD:737381 | 6480464 | Clonidine binds to and results in increased activity of ADRA2A protein | CTD | PMID:10217548 |
| clonidine (amino form) | multiple interactions | EXP | | 6480464 | [5-amino-7-(2-phenylethyl)-2-(2-furyl)pyrazolo(4,3-e)-1,2,4-triazolo(1,5-c)pyrimidine results in decreased activity of ADRA2A protein] which results in decreased susceptibility to Clonidine | CTD | PMID:17934014 PMID:16595736 |
| clonidine (amino form) | multiple interactions | ISO | RGD:10098 | 6480464 | Clonidine binds to and results in increased activity of ADRA2A protein | CTD | PMID:12598592 PMID:12560108 |
| clonidine (amino form) | multiple interactions | EXP | | 6480464 | [5-amino-7-(2-phenylethyl)-2-(2-furyl)pyrazolo(4,3-e)-1,2,4-triazolo(1,5-c)pyrimidine results in decreased activity of ADRA2A protein] which results in decreased susceptibility to Clonidine | CTD | PMID:16595736 PMID:17934014 |
| clonidine (amino form) | multiple interactions | ISO | RGD:10098 | 6480464 | Clonidine binds to and results in increased activity of ADRA2A protein | CTD | PMID:12560108 PMID:12598592 |
| clonidine (imino form) | multiple interactions | ISO | RGD:737381 | 6480464 | Clonidine binds to and results in increased activity of ADRA2A protein | CTD | PMID:10217548 |
| clonidine (imino form) | multiple interactions | EXP | | 6480464 | [5-amino-7-(2-phenylethyl)-2-(2-furyl)pyrazolo(4,3-e)-1,2,4-triazolo(1,5-c)pyrimidine results in decreased activity of ADRA2A protein] which results in decreased susceptibility to Clonidine | CTD | PMID:17934014 PMID:16595736 |
| clonidine (imino form) | multiple interactions | ISO | RGD:10098 | 6480464 | Clonidine binds to and results in increased activity of ADRA2A protein | CTD | PMID:12598592 PMID:12560108 |
| clonidine (imino form) | multiple interactions | EXP | | 6480464 | [5-amino-7-(2-phenylethyl)-2-(2-furyl)pyrazolo(4,3-e)-1,2,4-triazolo(1,5-c)pyrimidine results in decreased activity of ADRA2A protein] which results in decreased susceptibility to Clonidine | CTD | PMID:16595736 PMID:17934014 |
| clonidine (imino form) | multiple interactions | ISO | RGD:10098 | 6480464 | Clonidine binds to and results in increased activity of ADRA2A protein | CTD | PMID:12560108 PMID:12598592 |
| coumestrol | multiple interactions | ISO | RGD:737381 | 6480464 | ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of ADRA2A mRNA] | CTD | PMID:18310284 |
| crocidolite asbestos | affects expression | ISO | RGD:737381 | 6480464 | Asbestos, Crocidolite affects the expression of ADRA2A mRNA | CTD | PMID:17331233 |
| cyanazine | affects binding | EXP | | 6480464 | cyanazine binds to ADRA2A protein | CTD | PMID:11071396 |
| cyanazine | affects activity | EXP | | 6480464 | cyanazine affects the activity of ADRA2A protein | CTD | PMID:11071396 |
| dexmedetomidine | multiple interactions | ISO | RGD:737381 | 6480464 | Dexmedetomidine inhibits the reaction [Norepinephrine binds to and results in increased activity of ADRA2A protein] | CTD | PMID:10742289 |
| dexmedetomidine | multiple interactions | ISO | RGD:737381 | 6480464 | Dexmedetomidine binds to and results in increased activity of ADRA2A protein | CTD | PMID:15627480 |
| diazinon | increases expression | EXP | | 6480464 | Diazinon results in increased expression of ADRA2A mRNA | CTD | PMID:17452286 |
| dobutamine | multiple interactions | ISO | RGD:737381 | 6480464 | Dobutamine binds to and results in increased activity of ADRA2A protein | CTD | PMID:16024912 |
| dopamine | affects binding | ISO | RGD:10098 | 6480464 | Dopamine binds to ADRA2A protein | CTD | PMID:10336518 |
| doxazosin | multiple interactions | ISO | RGD:737381 | 6480464 | Doxazosin inhibits the reaction [Norepinephrine binds to and results in increased activity of ADRA2A protein] | CTD | PMID:10742289 |
| doxazosin | decreases expression | ISO | RGD:737381 | 6480464 | Doxazosin results in decreased expression of ADRA2A protein | CTD | PMID:10694191 |
| doxazosin | increases activity | ISO | RGD:737381 | 6480464 | Doxazosin results in increased activity of ADRA2A protein | CTD | PMID:10694191 |
| folic acid | multiple interactions | ISO | RGD:10098 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ADRA2A gene | CTD | PMID:20938992 |
| idazoxan | multiple interactions | EXP | | 6480464 | [Idazoxan binds to and results in decreased activity of ADRA2A protein] which results in decreased susceptibility to amitraz | CTD | PMID:10582558 |
| indapamide | increases expression | ISO | RGD:737381 | 6480464 | Indapamide results in increased expression of ADRA2A protein | CTD | PMID:2829625 |
| isotretinoin | increases expression | ISO | RGD:737381 | 6480464 | Isotretinoin results in increased expression of ADRA2A mRNA | CTD | PMID:20436886 |
| L-methionine | multiple interactions | ISO | RGD:10098 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ADRA2A gene | CTD | PMID:20938992 |
| medetomidine | multiple interactions | ISO | RGD:10098 | 6480464 | Medetomidine binds to and results in increased activity of ADRA2A protein | CTD | PMID:12598592 |
| medetomidine | affects response to substance | ISO | RGD:10098 | 6480464 | ADRA2A protein affects the susceptibility to Medetomidine | CTD | PMID:20083574 |
| nickel atom | increases expression | EXP | | 6480464 | Nickel results in increased expression of ADRA2A mRNA | CTD | PMID:18812211 |
| oxcarbazepine | multiple interactions | EXP | | 6480464 | [BRL 44408 binds to and results in decreased activity of ADRA2A protein] which results in decreased susceptibility to oxcarbazepine | CTD | PMID:17959985 |
| paracetamol | affects expression | ISO | RGD:10098 | 6480464 | Acetaminophen affects the expression of ADRA2A mRNA | CTD | PMID:17562736 |
| paracetamol | decreases expression | ISO | RGD:737381 | 6480464 | Acetaminophen results in decreased expression of ADRA2A mRNA | CTD | PMID:22230336 |
| phenobarbital | affects expression | ISO | RGD:10098 | 6480464 | Phenobarbital affects the expression of ADRA2A mRNA | CTD | PMID:19136022 |
| phenylephrine | multiple interactions | ISO | RGD:737381 | 6480464 | brimonidine promotes the reaction [Phenylephrine binds to and results in increased activity of ADRA2A protein]; more ... | CTD | PMID:10742289 |
| pirinixic acid | multiple interactions | ISO | RGD:10098 | 6480464 | NCF1 protein affects the reaction [pirinixic acid results in decreased expression of ADRA2A mRNA]; more ... | CTD | PMID:17950772 |
| pirinixic acid | increases expression | ISO | RGD:10098 | 6480464 | pirinixic acid results in increased expression of ADRA2A mRNA | CTD | PMID:20813756 PMID:18301758 |
| pirinixic acid | increases expression | ISO | RGD:10098 | 6480464 | pirinixic acid results in increased expression of ADRA2A mRNA | CTD | PMID:18301758 PMID:20813756 |
| pirinixic acid | decreases expression | ISO | RGD:10098 | 6480464 | pirinixic acid results in decreased expression of ADRA2A mRNA | CTD | PMID:17950772 |
| pirinixic acid | multiple interactions | ISO | RGD:10098 | 6480464 | [pirinixic acid co-treated with PPARA] results in increased expression of ADRA2A mRNA | CTD | PMID:20813756 |
| pirinixic acid | multiple interactions | ISO | RGD:10098 | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of ADRA2A mRNA | CTD | PMID:19710929 |
| pirinixic acid | affects expression | ISO | RGD:10098 | 6480464 | pirinixic acid affects the expression of ADRA2A mRNA | CTD | PMID:19136022 |
| potassium atom | multiple interactions | EXP | | 6480464 | [BRL 44408 binds to and results in decreased activity of ADRA2A protein] inhibits the reaction [Xylazine inhibits the reaction [Potassium results in increased secretion of Norepinephrine]] | CTD | PMID:11312645 |
| prazosin | multiple interactions | ISO | RGD:737381 | 6480464 | Prazosin inhibits the reaction [Norepinephrine binds to and results in increased activity of ADRA2A protein]; more ... | CTD | PMID:10742289 |
| prazosin | multiple interactions | EXP | | 6480464 | Prazosin binds to and results in decreased activity of ADRA2A protein | CTD | PMID:8397342 |
| progesterone | increases expression | ISO | RGD:10098 | 6480464 | Progesterone results in increased expression of ADRA2A mRNA | CTD | PMID:15713686 |
| reserpine | increases expression | EXP | | 6480464 | Reserpine results in increased expression of ADRA2A mRNA | CTD | PMID:11264240 |
| testosterone | increases expression | ISO | RGD:10098 | 6480464 | Testosterone results in increased expression of ADRA2A mRNA | CTD | PMID:15713686 |
| tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of ADRA2A mRNA | CTD | PMID:16644059 |
| thapsigargin | multiple interactions | ISO | RGD:737381 | 6480464 | Thapsigargin inhibits the reaction [Norepinephrine binds to and results in increased activity of ADRA2A protein] | CTD | PMID:10742289 |
| yohimbine | multiple interactions | ISO | RGD:737381 | 6480464 | Yohimbine inhibits the reaction [brimonidine promotes the reaction [Phenylephrine binds to and results in increased activity of ADRA2A protein]]; more ... | CTD | PMID:10742289 |
| yohimbine | multiple interactions | ISO | RGD:10098 | 6480464 | Yohimbine binds to and results in decreased activity of ADRA2A protein | CTD | PMID:17666864 |
| yohimbine | multiple interactions | EXP | | 6480464 | Yohimbine binds to and results in decreased activity of ADRA2A protein | CTD | PMID:8397342 |