Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | increases expression | ISO | Cdc42ep1 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of CDC42EP1 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | multiple interactions | ISO | Cdc42ep1 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CDC42EP1 mRNA | CTD | PMID:17942748 | 17beta-estradiol | increases expression | ISO | CDC42EP1 (Homo sapiens) | 6480464 | Estradiol results in increased expression of CDC42EP1 mRNA | CTD | PMID:23019147 and PMID:31614463 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Cdc42ep1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of CDC42EP1 mRNA | CTD | PMID:19933214 | 2,3,7,8-tetrachlorodibenzodioxine | decreases phosphorylation | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased phosphorylation of CDC42EP1 protein | CTD | PMID:23298284 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Cdc42ep1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of CDC42EP1 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | AHR protein alternative form affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of CDC42EP1 mRNA] | CTD | PMID:21215274 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of CDC42EP1 mRNA | CTD | PMID:21215274 and PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Cdc42ep1 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CDC42EP1 mRNA | CTD | PMID:17942748 | 3,4-methylenedioxymethamphetamine | increases expression | ISO | Cdc42ep1 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of CDC42EP1 mRNA | CTD | PMID:20188158 | 4,4'-sulfonyldiphenol | increases expression | ISO | Cdc42ep1 (Mus musculus) | 6480464 | bisphenol S results in increased expression of CDC42EP1 mRNA | CTD | PMID:30951980 | 4,4'-sulfonyldiphenol | increases methylation | ISO | Cdc42ep1 (Mus musculus) | 6480464 | bisphenol S results in increased methylation of CDC42EP1 exon | CTD | PMID:33297965 | 4-hydroxyphenyl retinamide | decreases expression | ISO | Cdc42ep1 (Mus musculus) | 6480464 | Fenretinide results in decreased expression of CDC42EP1 mRNA | CTD | PMID:28973697 | 5-fluorouracil | affects response to substance | ISO | CDC42EP1 (Homo sapiens) | 6480464 | CDC42EP1 protein affects the susceptibility to Fluorouracil | CTD | PMID:16217747 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of CDC42EP1 mRNA | CTD | PMID:24780913 and PMID:25825206 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of CDC42EP1 mRNA | CTD | PMID:30047161 | acrylamide | decreases expression | EXP | | 6480464 | Acrylamide results in decreased expression of CDC42EP1 mRNA | CTD | PMID:28959563 | all-trans-retinoic acid | multiple interactions | ISO | Cdc42ep1 (Mus musculus) | 6480464 | [bisphenol F co-treated with Tretinoin] results in decreased expression of CDC42EP1 mRNA | CTD | PMID:30951980 | amitrole | increases expression | EXP | | 6480464 | Amitrole results in increased expression of CDC42EP1 mRNA | CTD | PMID:30047161 | aristolochic acids | increases expression | EXP | | 6480464 | Aristolochic Acids results in increased expression of CDC42EP1 mRNA | CTD | PMID:19717638 | atrazine | increases expression | ISO | CDC42EP1 (Homo sapiens) | 6480464 | Atrazine results in increased expression of CDC42EP1 mRNA | CTD | PMID:22378314 | benzo[a]pyrene | decreases expression | ISO | Cdc42ep1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of CDC42EP1 mRNA | CTD | PMID:21569818 | benzo[a]pyrene | increases expression | ISO | CDC42EP1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of CDC42EP1 mRNA | CTD | PMID:32234424 | benzo[a]pyrene | increases methylation | ISO | CDC42EP1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of CDC42EP1 3' UTR | CTD | PMID:27901495 | benzo[a]pyrene | decreases methylation | ISO | CDC42EP1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of CDC42EP1 promoter | CTD | PMID:27901495 | benzo[a]pyrene | increases expression | ISO | Cdc42ep1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of CDC42EP1 mRNA | CTD | PMID:22228805 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of CDC42EP1 mRNA | CTD | PMID:30816183 more ... | bisphenol A | increases expression | ISO | Cdc42ep1 (Mus musculus) | 6480464 | bisphenol A results in increased expression of CDC42EP1 mRNA | CTD | PMID:32156529 and PMID:34585602 | bisphenol A | affects expression | ISO | CDC42EP1 (Homo sapiens) | 6480464 | bisphenol A affects the expression of CDC42EP1 mRNA | CTD | PMID:30903817 | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of CDC42EP1 gene | CTD | PMID:28505145 | bisphenol F | increases expression | ISO | Cdc42ep1 (Mus musculus) | 6480464 | bisphenol F results in increased expression of CDC42EP1 mRNA | CTD | PMID:30951980 | bisphenol F | multiple interactions | ISO | Cdc42ep1 (Mus musculus) | 6480464 | [bisphenol F co-treated with Tretinoin] results in decreased expression of CDC42EP1 mRNA | CTD | PMID:30951980 | Brodifacoum | decreases expression | EXP | | 6480464 | bromfenacoum results in decreased expression of CDC42EP1 protein | CTD | PMID:28903499 | cadmium atom | multiple interactions | ISO | CDC42EP1 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of CDC42EP1 mRNA | CTD | PMID:35301059 | cadmium dichloride | decreases expression | ISO | CDC42EP1 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of CDC42EP1 mRNA | CTD | PMID:30998937 | cadmium dichloride | multiple interactions | ISO | CDC42EP1 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of CDC42EP1 mRNA | CTD | PMID:35301059 | caffeine | affects phosphorylation | ISO | CDC42EP1 (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of CDC42EP1 protein | CTD | PMID:35688186 | cisplatin | decreases expression | ISO | CDC42EP1 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of CDC42EP1 mRNA | CTD | PMID:27392435 | cisplatin | multiple interactions | ISO | CDC42EP1 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of CDC42EP1 mRNA | CTD | PMID:27392435 | clobetasol | increases expression | ISO | Cdc42ep1 (Mus musculus) | 6480464 | Clobetasol results in increased expression of CDC42EP1 mRNA | CTD | PMID:27462272 | cobalt dichloride | decreases expression | ISO | CDC42EP1 (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of CDC42EP1 mRNA | CTD | PMID:19320972 | coumarin | increases phosphorylation | ISO | CDC42EP1 (Homo sapiens) | 6480464 | coumarin results in increased phosphorylation of CDC42EP1 protein | CTD | PMID:35688186 | Cuprizon | decreases expression | EXP | | 6480464 | Cuprizone results in decreased expression of CDC42EP1 mRNA | CTD | PMID:27523638 | cyclosporin A | increases expression | ISO | CDC42EP1 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of CDC42EP1 mRNA | CTD | PMID:25562108 | diazinon | increases methylation | ISO | CDC42EP1 (Homo sapiens) | 6480464 | Diazinon results in increased methylation of CDC42EP1 gene | CTD | PMID:22964155 | dibutyl phthalate | increases expression | ISO | Cdc42ep1 (Mus musculus) | 6480464 | Dibutyl Phthalate results in increased expression of CDC42EP1 mRNA | CTD | PMID:17361019 and PMID:21266533 | dicrotophos | increases expression | ISO | CDC42EP1 (Homo sapiens) | 6480464 | dicrotophos results in increased expression of CDC42EP1 mRNA | CTD | PMID:28302478 | fenamidone | increases expression | ISO | Cdc42ep1 (Mus musculus) | 6480464 | fenamidone results in increased expression of CDC42EP1 mRNA | CTD | PMID:27029645 | FR900359 | affects phosphorylation | ISO | CDC42EP1 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of CDC42EP1 protein | CTD | PMID:37730182 | furan | increases methylation | EXP | | 6480464 | furan results in increased methylation of CDC42EP1 gene | CTD | PMID:22079235 | genistein | increases expression | ISO | CDC42EP1 (Homo sapiens) | 6480464 | Genistein results in increased expression of CDC42EP1 mRNA | CTD | PMID:23019147 | lead(0) | affects expression | ISO | CDC42EP1 (Homo sapiens) | 6480464 | Lead affects the expression of CDC42EP1 mRNA | CTD | PMID:28903495 | methimazole | increases expression | EXP | | 6480464 | Methimazole results in increased expression of CDC42EP1 mRNA | CTD | PMID:30047161 | N-methyl-4-phenylpyridinium | increases expression | ISO | CDC42EP1 (Homo sapiens) | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of CDC42EP1 mRNA | CTD | PMID:24810058 | N-Nitrosopyrrolidine | increases expression | ISO | CDC42EP1 (Homo sapiens) | 6480464 | N-Nitrosopyrrolidine results in increased expression of CDC42EP1 mRNA | CTD | PMID:32234424 | niclosamide | increases expression | ISO | CDC42EP1 (Homo sapiens) | 6480464 | Niclosamide results in increased expression of CDC42EP1 mRNA | CTD | PMID:36318118 | ochratoxin A | increases expression | EXP | | 6480464 | ochratoxin A results in increased expression of CDC42EP1 mRNA | CTD | PMID:19717638 | orphenadrine | affects expression | EXP | | 6480464 | Orphenadrine affects the expression of CDC42EP1 mRNA | CTD | PMID:23665939 | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in increased expression of CDC42EP1 mRNA | CTD | PMID:25729387 | ozone | multiple interactions | ISO | Cdc42ep1 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of CDC42EP1 mRNA | CTD | PMID:34911549 | p-toluidine | increases expression | EXP | | 6480464 | 4-toluidine results in increased expression of CDC42EP1 mRNA | CTD | PMID:27638505 | paracetamol | affects expression | ISO | Cdc42ep1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of CDC42EP1 mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of CDC42EP1 mRNA | CTD | PMID:33387578 | paracetamol | increases expression | ISO | CDC42EP1 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of CDC42EP1 mRNA | CTD | PMID:29067470 | paraquat | decreases expression | ISO | Cdc42ep1 (Mus musculus) | 6480464 | Paraquat results in decreased expression of CDC42EP1 mRNA | CTD | PMID:21463325 | perfluorononanoic acid | increases expression | ISO | CDC42EP1 (Homo sapiens) | 6480464 | perfluoro-n-nonanoic acid results in increased expression of CDC42EP1 mRNA | CTD | PMID:32588087 | propiconazole | increases expression | EXP | | 6480464 | propiconazole results in increased expression of CDC42EP1 mRNA | CTD | PMID:30047161 | quercetin | increases phosphorylation | ISO | CDC42EP1 (Homo sapiens) | 6480464 | Quercetin results in increased phosphorylation of CDC42EP1 protein | CTD | PMID:35688186 | rotenone | increases expression | ISO | CDC42EP1 (Homo sapiens) | 6480464 | Rotenone results in increased expression of CDC42EP1 mRNA | CTD | PMID:29955902 | sulfadimethoxine | increases expression | EXP | | 6480464 | Sulfadimethoxine results in increased expression of CDC42EP1 mRNA | CTD | PMID:30047161 | sulindac | increases expression | ISO | CDC42EP1 (Homo sapiens) | 6480464 | Sulindac results in increased expression of CDC42EP1 mRNA | CTD | PMID:11906190 | sunitinib | increases expression | ISO | CDC42EP1 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of CDC42EP1 mRNA | CTD | PMID:31533062 | testosterone | increases expression | ISO | CDC42EP1 (Homo sapiens) | 6480464 | Testosterone results in increased expression of CDC42EP1 mRNA | CTD | PMID:33359661 | testosterone undecanoate | decreases expression | ISO | CDC42EP1 (Homo sapiens) | 6480464 | testosterone undecanoate results in decreased expression of CDC42EP1 mRNA | CTD | PMID:19074003 | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of CDC42EP1 mRNA | CTD | PMID:31150632 | Theaflavin 3,3'-digallate | affects expression | ISO | CDC42EP1 (Homo sapiens) | 6480464 | theaflavin-3 and 3'-digallate affects the expression of CDC42EP1 mRNA | CTD | PMID:34925699 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of CDC42EP1 mRNA | CTD | PMID:23411599 and PMID:34492290 | titanium dioxide | decreases expression | ISO | Cdc42ep1 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of CDC42EP1 mRNA | CTD | PMID:23557971 and PMID:29264374 | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in increased expression of CDC42EP1 mRNA | CTD | PMID:25729387 | triclosan | increases expression | ISO | CDC42EP1 (Homo sapiens) | 6480464 | Triclosan results in increased expression of CDC42EP1 mRNA | CTD | PMID:30510588 | trimellitic anhydride | decreases expression | ISO | Cdc42ep1 (Mus musculus) | 6480464 | trimellitic anhydride results in decreased expression of CDC42EP1 mRNA | CTD | PMID:19042947 | valproic acid | decreases expression | ISO | CDC42EP1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of CDC42EP1 mRNA | CTD | PMID:29154799 | |