Palm (paralemmin) - Rat Genome Database

Name: Palm
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Palm (paralemmin) Rattus norvegicus

Analyze

Symbol:

Palm

Name:

paralemmin

RGD ID:

620341

Description:

Predicted to enable D3 dopamine receptor binding activity. Predicted to be involved in several processes, including cellular response to electrical stimulus; negative regulation of dopamine receptor signaling pathway; and positive regulation of filopodium assembly. Predicted to act upstream of or within several processes, including adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; cytoskeleton organization; and regulation of cell shape. Located in several cellular components, including apicolateral plasma membrane; basolateral plasma membrane; and dendritic spine membrane. Orthologous to human PALM (paralemmin); INTERACTS WITH 3,3',4,4',5-pentachlorobiphenyl; 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

paralemmin-1

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PALM (paralemmin)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Palm (paralemmin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Palm (paralemmin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PALM (paralemmin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PALM (paralemmin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Palm (paralemmin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PALM (paralemmin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PALM (paralemmin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Palm (paralemmin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	TSG101 (tumor susceptibility 101)	HGNC	OMA
Alliance orthologs ³
Mus musculus (house mouse):	Palm (paralemmin)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	PALM (paralemmin)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	palm1a (paralemmin 1a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	palm1b (paralemmin 1b)	Alliance	DIOPT (OMA\|OrthoFinder\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	palm	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	10,537,252 - 10,563,346 (-)	NCBI		GRCr8
mRatBN7.2	7	9,886,634 - 9,912,389 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	9,886,643 - 9,912,555 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	12,767,145 - 12,793,514 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	14,645,225 - 14,671,595 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	12,505,013 - 12,530,920 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	12,708,024 - 12,721,055 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	12,708,015 - 12,793,711 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	12,877,746 - 12,890,777 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	11,399,529 - 11,425,964 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	11,399,539 - 11,425,963 (-)	NCBI
Celera	7	8,061,307 - 8,085,800 (-)	NCBI		Celera
Cytogenetic Map	7	q11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

cerebral creatine deficiency syndrome (ISO)

cyclic hematopoiesis (ISO)

genetic disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17beta-estradiol (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

3,3',4,4',5-pentachlorobiphenyl (EXP)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-sulfonyldiphenol (EXP,ISO)

6-propyl-2-thiouracil (EXP)

aconitine (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

allethrin (EXP)

ammonium chloride (EXP)

arsane (ISO)

arsenic atom (ISO)

atrazine (EXP)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bis(2-ethylhexyl) phthalate (EXP)

bisphenol A (EXP,ISO)

Bisphenol B (ISO)

bisphenol F (EXP,ISO)

Brodifacoum (EXP)

chlorpyrifos (ISO)

choline (ISO)

cisplatin (ISO)

coumarin (ISO)

cyhalothrin (EXP)

cypermethrin (EXP)

dibutyl phthalate (EXP,ISO)

dioxygen (ISO)

endosulfan (EXP)

fenvalerate (EXP)

folic acid (ISO)

FR900359 (ISO)

fulvestrant (ISO)

genistein (ISO)

gentamycin (EXP)

indole-3-methanol (EXP)

L-methionine (ISO)

Mesaconitine (EXP)

methapyrilene (ISO)

methimazole (EXP)

nickel atom (ISO)

niclosamide (ISO)

ozone (ISO)

paracetamol (EXP,ISO)

perfluorohexanesulfonic acid (ISO)

pyrethrins (EXP)

sulfadimethoxine (EXP)

sulforaphane (ISO)

sunitinib (ISO)

testosterone (ISO)

tetrachloromethane (EXP)

thioacetamide (EXP)

triptonide (ISO)

tungsten (ISO)

valproic acid (ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (IEA,ISO)

cellular response to electrical stimulus (IEA,ISO)

cytoskeleton organization (IEA,ISO)

negative regulation of dopamine receptor signaling pathway (IEA,ISO)

positive regulation of dendritic spine development (ISO)

positive regulation of filopodium assembly (IBA,IEA,ISO)

protein localization (ISO)

protein localization to plasma membrane (IEA,ISO)

regulation of cell shape (IEA,ISO)

regulation of postsynapse assembly (IDA,IMP)

synapse maturation (IEA,ISO)

Cellular Component

apicolateral plasma membrane (IDA,IEA)

axon (IDA,IEA)

basolateral plasma membrane (IDA,IEA)

cytoplasm (IEA,ISO)

cytoplasmic side of plasma membrane (TAS)

dendrite (IEA)

dendrite membrane (IDA)

dendritic spine membrane (IDA)

filopodium (ISO)

filopodium membrane (IEA,ISO)

glutamatergic synapse (IDA,IMP)

lateral plasma membrane (IEA)

neuron spine (IEA,ISO)

nucleoplasm (IEA,ISO)

plasma membrane (IBA,IDA,ISO)

postsynapse (IDA,IMP)

postsynaptic density (IEA,ISO)

synapse (IEA)

Molecular Function

D3 dopamine receptor binding (IEA,ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Paralemmin-1, a modulator of filopodia induction is required for spine maturation.	Arstikaitis P, etal., Mol Biol Cell. 2008 May;19(5):2026-38. doi: 10.1091/mbc.E07-08-0802. Epub 2008 Feb 20.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	The paralemmin protein family: identification of paralemmin-2, an isoform differentially spliced to AKAP2/AKAP-KL, and of palmdelphin, a more distant cytosolic relative.	Hu B, etal., Biochem Biophys Res Commun 2001 Aug 3;285(5):1369-76.
4.	Cellular and subcellular localization of paralemmin-1, a protein involved in cell shape control, in the rat brain, adrenal gland and kidney.	Kutzleb C, etal., Histochem Cell Biol. 2007 Jan;127(1):13-30. Epub 2006 Jul 18.
5.	Paralemmin, a prenyl-palmitoyl-anchored phosphoprotein abundant in neurons and implicated in plasma membrane dynamics and cell process formation.	Kutzleb C, etal., J Cell Biol 1998 Nov 2;143(3):795-813.
6.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
7.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
8.	GOA pipeline	RGD automated data pipeline
9.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
11.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:14978216	PMID:16386234	PMID:17114649	PMID:22871113

Genomics

Comparative Map Data

Palm
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	10,537,252 - 10,563,346 (-)	NCBI		GRCr8
mRatBN7.2	7	9,886,634 - 9,912,389 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	9,886,643 - 9,912,555 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	12,767,145 - 12,793,514 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	14,645,225 - 14,671,595 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	12,505,013 - 12,530,920 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	12,708,024 - 12,721,055 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	12,708,015 - 12,793,711 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	12,877,746 - 12,890,777 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	11,399,529 - 11,425,964 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	11,399,539 - 11,425,963 (-)	NCBI
Celera	7	8,061,307 - 8,085,800 (-)	NCBI		Celera
Cytogenetic Map	7	q11	NCBI

PALM
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	708,935 - 748,329 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	708,935 - 748,329 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	708,935 - 748,329 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	659,953 - 699,330 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	660,001 - 699,328	NCBI
Celera	19	68,034 - 107,470 (-)	NCBI		Celera
Cytogenetic Map	19	p13.3	NCBI
HuRef	19	489,142 - 517,994 (+)	NCBI		HuRef
CHM1_1	19	676,096 - 747,789 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	19	662,950 - 702,386 (+)	NCBI		T2T-CHM13v2.0

Palm
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	79,629,406 - 79,656,749 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	79,629,406 - 79,656,730 (+)	Ensembl		GRCm39 Ensembl
GRCm38	10	79,793,572 - 79,820,915 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	79,793,572 - 79,820,896 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	79,256,317 - 79,283,641 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	10	79,196,845 - 79,224,025 (+)	NCBI		MGSCv36	mm8
Celera	10	80,808,272 - 80,835,695 (+)	NCBI		Celera
Cytogenetic Map	10	C1	NCBI
cM Map	10	39.72	NCBI

Palm
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955495	7,046,261 - 7,055,548 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955495	7,044,942 - 7,060,022 (-)	NCBI	ChiLan1.0	ChiLan1.0

PALM
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	5,035,677 - 5,076,482 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	4,273,672 - 4,314,579 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	386,417 - 427,178 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	695,390 - 714,980 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	693,853 - 713,465 (+)	Ensembl	panpan1.1		panPan2

PALM
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	57,847,631 - 57,868,790 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	57,849,081 - 57,868,975 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	57,649,827 - 57,670,978 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	58,590,141 - 58,611,532 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	58,590,140 - 58,611,717 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	57,644,561 - 57,665,710 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	58,124,083 - 58,145,219 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	58,327,378 - 58,348,540 (-)	NCBI		UU_Cfam_GSD_1.0

Palm
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	217,550,858 - 217,570,299 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936588	270,425 - 283,974 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936588	270,431 - 283,925 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PALM
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	77,619,199 - 77,644,673 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	77,619,199 - 77,644,561 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	78,333,780 - 78,352,317 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PALM
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	461,030 - 503,688 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	474,474 - 504,230 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666081	8,454,145 - 8,494,136 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Palm
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624828	7,811,199 - 7,834,011 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624828	7,812,108 - 7,833,986 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Palm
271 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	478
Count of miRNA genes:	230
Interacting mature miRNAs:	259
Transcripts:	ENSRNOT00000013762
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2298550	Neuinf6	Neuroinflammation QTL 6	3.3		nervous system integrity trait (VT:0010566)	spinal cord RT1-B protein level (CMO:0002132)	7	1	27829089	Rat
7411566	Bw136	Body weight QTL 136	10.4	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	7	1	31962314	Rat
9590142	Scort5	Serum corticosterone level QTL 5	24.4	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	7	1	31962314	Rat
724560	Plsm3	Polydactyly-luxate syndrome (PLS) morphotypes QTL 3		0.0003	tibia length (VT:0004357)	tibia length (CMO:0000450)	7	1	34000259	Rat
2317047	Wbc4	White blood cell count QTL 4		0.01	leukocyte quantity (VT:0000217)	white blood cell count (CMO:0000027)	7	1	35342956	Rat
61410	Bw19	Body weight QTL 19	6.2	0.001	body mass (VT:0001259)	body weight (CMO:0000012)	7	1	44782185	Rat
631503	Bp102	Blood pressure QTL 102	1.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	1	44822433	Rat
1300176	Hrtrt10	Heart rate QTL 10	3.19		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	7	664270	26029351	Rat
634336	Anxrr17	Anxiety related response QTL 17	3.66		locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	7	924703	115097879	Rat
10755438	Coatc9	Coat color QTL 9		0	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	7	3529280	48529280	Rat
9590102	Sffal5	Serum free fatty acids level QTL 5	8.62	0.001	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	7	5329019	50329019	Rat
10755440	Coatc10	Coat color QTL 10		0	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	7	7496499	52496499	Rat
10059592	Kidm45	Kidney mass QTL 45	3.95	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	7	7573985	52573985	Rat
2298547	Neuinf5	Neuroinflammation QTL 5	3.7		nervous system integrity trait (VT:0010566)	spinal cord Cd74 protein level (CMO:0002131)	7	9462246	58265113	Rat
1643004	Pain2	Pain QTL 2	1		mechanical nociception trait (VT:0002734)	self mutilation severity score (CMO:0002145)	7	9462246	98011544	Rat
1578652	Bmd15	Bone mineral density QTL 15	5.2		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	7	9866467	60460686	Rat

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	2	35	7	6	2	6		2	74	35	33	7
Low	1	8	50	35	17	35	8	9			8	4	8
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_130829	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039078326	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039078327	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB058889	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC072525	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474029	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ227613	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ232905	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000013762 ⟹ ENSRNOP00000013762

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	7	9,886,659 - 9,912,385 (-)	Ensembl
Rnor_6.0 Ensembl	7	12,708,015 - 12,793,711 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000110910 ⟹ ENSRNOP00000096200

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	7	9,886,643 - 9,900,469 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000114530 ⟹ ENSRNOP00000080900

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	7	9,886,643 - 9,912,555 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000117256 ⟹ ENSRNOP00000093376

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	7	9,892,092 - 9,912,294 (-)	Ensembl

RefSeq Acc Id:

NM_130829 ⟹ NP_570842

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	10,537,252 - 10,563,007 (-)	NCBI
mRatBN7.2	7	9,886,634 - 9,912,385 (-)	NCBI
Rnor_6.0	7	12,708,024 - 12,721,055 (-)	NCBI
Rnor_5.0	7	12,877,746 - 12,890,777 (-)	NCBI
RGSC_v3.4	7	11,399,529 - 11,425,964 (-)	RGD
Celera	7	8,061,307 - 8,085,800 (-)	RGD

Sequence:

show sequence

TGGCCACGCGTCGACTAGTACGGGGGGGGGGGGTGGCCCACGGACCTCGCGGGAGATGGAGGTC
CTGGCGACAGACACTGTGTCCCAGCAGGAGCGGCTTCAAGCAATCGCTGAGAAGCGTAGGAAGC
AGGCAGAGATTGAGAGCAAGCGGAGACAATTGGAGGATGACCGAAGACAGCTGCAGTACCTGAA
GTCCAAGGCACTTCGGGAACGCTGGCTGCTGGAGGGGACACCATCCTCAGCCTCGGAGGGCGAC
GAGGACATGAGGAAGCAGATGCAGGAGGATGAACAGAAAGCCCGGAGCCTGGAGGAGTCCATCA
CCAGACTCGAGAAAGAAATTGATGTCCTGGAGTTCGGTGAGTCAGCCCCAGCTGCCCCAAAGGA
GAACTCAGCGGCCCCCAGCCCCATCCGGCCCCACTCTACAAGCCCCGCCAAGGAGGAGCAAAAG
TCAGAAACCATGGTGAACGCCCAGCAGACTCCACTGGGCACCCCAAAAGAGAATCGAAAGTCCA
CACCGGTGCGGAGTCCCGGGGGATCCACGATGATGAAGGCAGCCATGTATTCGGTGGAGATCAC
GGTGGAGAAGGACAAGGTGACCGGGGAGACCAGGGTGCTGTCCAGCACCACATTGCTCCCCCGG
GACCCACTCCCTCAGGGCGTGAAAGTCTACGAGGACGAAACAAAAGTGGTCCATGCCGTGGACG
GCCTCTCTGAGAACGGAATCCAGCCTCTAAGTTCCTCCGAGGTGGATGAACTCATTCACAAGGC
CGATGAGGTCACACTGAGTGAGGCCGGGTCCACAACTGGGCCAGCAGAGCCTCGGGGACTCGCA
GAGGATGTCACCAGGACCACACCATCCAGAAGGGAGATCACAGGAGTCGAGGCTCAGCCAGGAG
AGGCCACGTCAGGCCCGCCAGGCATCCAGCCCGGTCAGGAGCCCCCGGTCACCATGGTCTTCAT
GGGTTATCAGAATGTGGAAGATGAAGCAGAGACCAAGAAGGTACTCGGCCTGCAGGACACCATC
AAGGCTGAACTGGTGGTGATTGAAGACTCGGTCACCCCCAGGGAGCCTGCACCACTCAATGGCA
GCGCGGCTGAGCTCCCAGCCACCAAGGAGGAGAACCAGACGGGGCCCACGACCACACCCAGCGA
CACCCAAGATCTTGACATGAAGAAGCCTCGCTGTAGATGCTGTTCTGTCATGTGAGCCGTCGGG
GCACCCCAGTCCCCGGTCCCTGTCCTATGCTCCACACTCAAACCCAGCAGCCCGGCCCTCCCCG
GCGCCTGCCCACCTTCACCCTCCGCCTCACAGGCCCCAGACACGTGTGTGGTCCCTATGAACCT
CGAGTCGCGGGTGGGGGGTGCTGTGCCCGTCACCACACTCCACACTCACCCCGTACCTCTGAGC
CGTGTGTCATCCCTTGGTGAGAGACAGGCTGACCCTTATCAGCCCCTCTAAGAATGGGGATCCC
CCCAGTCCAGGTCACAGCAGGTTTACACAGGTGGCTTATGCCCACCATGGTCCCAGCCTGGTGT
CCCCTTGCCGCCCCAGGCCAGCCTGTCTGTGCCTTATTGTTACTTTTGGGGAGTCTCCGAGGGG
ACCAGAAAGGCTCTCCCTGGCCAAGGCGCCAGCAGCCAAATGTGGGCAAGTGAGATGAGGCCAC
ACTTCTTTGGGGACTCAAAGTCTTGACGTCCTAACTTGGAAGACGGGCACCTGTGGATCCCCTC
CAGTAGGTAGCGGAGCTCAAAACAGGGGAAGCCCTTCACTGGGGATGGAACAGTCACCCACAAG
ATGGAGTCATTGTTGGTCAGCCAAGCCACTCCCTGTCCTAAGTGTCCCCTCCCCTCCATGCACA
CACTGGGCCCTTCTTCCTGGTGCTAATTTTGGGACCTTCGGGGTCACCTCTGCCCTCTTCTCTA
GTTGGCTTGGACCAGGGTCCTGGGTTTCCCACATACCCCCATACCCCAGAAGTCAGTGGGTATG
TCTGCCAGCACTGCAAAGCCTAGCGTTTCCAGGCAGGATTAGGTTGCTCCACACACACACCTTG
GGTGGGAGTAAGGGAACCCCCCACCTGCCACCTGGCCAGACGGGAGCCTGGCAGGAGGTCACCA
ACCTTCGGGCAGACAGGCAGCAGTAGCCACTTTGGTCCCCAGAAGCACAACCTTGCACACAGGC
GCCTGACTCAGCTTCAAAGGACCACGCCCGGTCCAGGTCCCTTTGCTTGGGACTCCAGCCTGGT
GTGCAGCAGGGCACAGGACCCCCTGCAGAGTCCCGTCACTACCCGCACTGCAGTAGGGCCACAA
GCAGAGGCCACGACGGGGTCTGTGTCCCGTCCTTCCCGTGGCCTGGAGGAGAGGCGCTCTTCAC
TGAGGGGTGACCCATGGCCACGGTCATGGTGCCCCTCCTTTTCCTCCTCCTCTGATTCTGCCTG
AGTTCCTCAAGCCCTGAGCCTCGGCTGAAGTGCCCTTGCTGCCCCCTTCTGCTTTTGACGTGTG
ACGAGGCCCCACCCTTCACCCCCATGTTTCTTGACTTTCCCAGAGAAACAGATTAAAAAAAAAA
AAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039078326 ⟹ XP_038934254

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	10,538,429 - 10,559,905 (-)	NCBI
mRatBN7.2	7	9,886,634 - 9,909,283 (-)	NCBI

RefSeq Acc Id:

XM_039078327 ⟹ XP_038934255

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	10,538,429 - 10,563,346 (-)	NCBI
mRatBN7.2	7	9,886,634 - 9,912,389 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_570842	(Get FASTA)	NCBI Sequence Viewer
	XP_038934254	(Get FASTA)	NCBI Sequence Viewer
	XP_038934255	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH72525	(Get FASTA)	NCBI Sequence Viewer
	BAB68565	(Get FASTA)	NCBI Sequence Viewer
	EDL89390	(Get FASTA)	NCBI Sequence Viewer
	EDL89391	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000013762
	ENSRNOP00000013762.5
	ENSRNOP00000080900
	ENSRNOP00000080900.1
	ENSRNOP00000093376.1
	ENSRNOP00000096200.1
	ENSRNOP00055047173
	ENSRNOP00060036737
	ENSRNOP00065027571
GenBank Protein	Q920Q0	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_570842 ⟸ NM_130829

- UniProtKB:

Q920Q0 (UniProtKB/Swiss-Prot), A0A8I6AUR8 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MEVLATDTVSQQERLQAIAEKRRKQAEIESKRRQLEDDRRQLQYLKSKALRERWLLEGTPSSAS
EGDEDMRKQMQEDEQKARSLEESITRLEKEIDVLEFGESAPAAPKENSAAPSPIRPHSTSPAKE
EQKSETMVNAQQTPLGTPKENRKSTPVRSPGGSTMMKAAMYSVEITVEKDKVTGETRVLSSTTL
LPRDPLPQGVKVYEDETKVVHAVDGLSENGIQPLSSSEVDELIHKADEVTLSEAGSTTGPAEPR
GLAEDVTRTTPSRREITGVEAQPGEATSGPPGIQPGQEPPVTMVFMGYQNVEDEAETKKVLGLQ
DTIKAELVVIEDSVTPREPAPLNGSAAELPATKEENQTGPTTTPSDTQDLDMKKPRCRCCSVM

hide sequence

RefSeq Acc Id:

ENSRNOP00000013762 ⟸ ENSRNOT00000013762

RefSeq Acc Id:	XP_038934255 ⟸ XM_039078327
- Peptide Label:	isoform X2
- UniProtKB:	A6K8X0 (UniProtKB/TrEMBL), A0A8I6AUR8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038934254 ⟸ XM_039078326
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6AUR8 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSRNOP00000093376 ⟸ ENSRNOT00000117256

RefSeq Acc Id:

ENSRNOP00000096200 ⟸ ENSRNOT00000110910

RefSeq Acc Id:

ENSRNOP00000080900 ⟸ ENSRNOT00000114530

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q920Q0-F1-model_v2	AlphaFold	Q920Q0	1-383	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620341	AgrOrtholog
BioCyc Gene	G2FUF-34890	BioCyc
Ensembl Genes	ENSRNOG00000009760	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ENSRNOG00055033087	UniProtKB/Swiss-Prot
	ENSRNOG00060025484	UniProtKB/Swiss-Prot
	ENSRNOG00065020362	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000013762	ENTREZGENE
	ENSRNOT00000013762.8	UniProtKB/Swiss-Prot
	ENSRNOT00000110910.1	UniProtKB/TrEMBL
	ENSRNOT00000114530.1	UniProtKB/TrEMBL
	ENSRNOT00000117256.1	UniProtKB/TrEMBL
	ENSRNOT00055057195	UniProtKB/Swiss-Prot
	ENSRNOT00060044311	UniProtKB/Swiss-Prot
	ENSRNOT00065034422	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7097177	IMAGE-MGC_LOAD
InterPro	Paralemmin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:170673	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:91516	IMAGE-MGC_LOAD
NCBI Gene	170673	ENTREZGENE
PANTHER	PARALEMMIN-1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PARALEMMIN-RELATED	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Paralemmin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Palm	PhenoGen
RatGTEx	ENSRNOG00000009760	RatGTEx
	ENSRNOG00055033087	RatGTEx
	ENSRNOG00060025484	RatGTEx
	ENSRNOG00065020362	RatGTEx
UniProt	A0A8I6AJZ7_RAT	UniProtKB/TrEMBL
	A0A8I6AUR8	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6G597_RAT	UniProtKB/TrEMBL
	A6K8X0	ENTREZGENE, UniProtKB/TrEMBL
	PALM_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2004-09-10	Palm	paralemmin			Symbol and Name status set to approved	1299863	APPROVED
2002-08-07	Palm	paralemmin			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar