GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bax | decreases expression | ISO | BAX (Homo sapiens) | 6480464 | CTD | Niclosamide results in decreased expression of BAX protein | PMID:28500234 | Bax | increases expression | ISO | BAX (Homo sapiens) | 6480464 | CTD | Niclosamide results in increased expression of BAX protein | PMID:25634333 PMID:26703449 PMID:35115509 | Bax | multiple interactions | ISO | BAX (Homo sapiens) | 6480464 | CTD | [Niclosamide binds to Polyethyleneimine] which results in increased expression of BAX mRNA; [Niclosamide co-treated with bicalutamide] results in increased expression of BAX protein; bicalutamide inhibits the reaction [Niclosamide results in decreased expression of BAX protein] | PMID:25988281 PMID:28500234 | |
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