Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | psoriasis | | ISO | AP1S3 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | | |
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Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | psoriasis | | ISO | AP1S3 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | | |
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# | Reference Title | Reference Citation |
1. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
2. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
3. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
Ap1s3 (Rattus norvegicus - Norway rat) |
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AP1S3 (Homo sapiens - human) |
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Ap1s3 (Mus musculus - house mouse) |
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Ap1s3 (Chinchilla lanigera - long-tailed chinchilla) |
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AP1S3 (Pan paniscus - bonobo/pygmy chimpanzee) |
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AP1S3 (Canis lupus familiaris - dog) |
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AP1S3 (Sus scrofa - pig) |
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AP1S3 (Chlorocebus sabaeus - green monkey) |
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Ap1s3 (Heterocephalus glaber - naked mole-rat) |
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Variants in Ap1s3
535 total Variants |
The detailed report is available here: | Full Report | CSV | TAB | Printer | ||||
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | Full Report | CSV | TAB | Printer | Gviewer |
RH141828 |
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alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
High | |||||||||||||
Medium | 3 | 24 | 23 | 16 | 17 | 16 | 34 | 22 | |||||
Low | 19 | 34 | 25 | 2 | 25 | 1 | 1 | 74 | 1 | 19 | 11 | 1 | |
Below cutoff | 7 | 9 | 7 |
RefSeq Transcripts | NM_001172150 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
XM_006245264 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_008767284 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039083976 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063267513 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063267514 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063267515 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063267516 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_346066 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GenBank Nucleotide | JAXUCZ010000009 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
RefSeq Acc Id: | ENSRNOT00000072160 ⟹ ENSRNOP00000067496 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000109252 ⟹ ENSRNOP00000086582 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000110411 ⟹ ENSRNOP00000088980 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | NM_001172150 ⟹ NP_001165621 | ||||||||||||||||||||||||
RefSeq Status: | INFERRED | ||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_008767284 ⟹ XP_008765506 | ||||||||||||||||
Type: | CODING | ||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_039083976 ⟹ XP_038939904 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | XM_063267513 ⟹ XP_063123583 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063267514 ⟹ XP_063123584 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063267515 ⟹ XP_063123585 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063267516 ⟹ XP_063123586 | ||||||||
Type: | CODING | ||||||||
Position: |
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Protein RefSeqs | NP_001165621 | (Get FASTA) | NCBI Sequence Viewer |
XP_008765506 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038939904 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063123583 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063123584 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063123585 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063123586 | (Get FASTA) | NCBI Sequence Viewer | |
Ensembl Protein | ENSRNOP00000067496 | ||
ENSRNOP00000067496.3 | |||
ENSRNOP00000086582.1 | |||
ENSRNOP00000088980.1 |
RefSeq Acc Id: | NP_001165621 ⟸ NM_001172150 |
- UniProtKB: | M0RD05 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_008765506 ⟸ XM_008767284 |
- Peptide Label: | isoform X4 |
- UniProtKB: | M0RD05 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | ENSRNOP00000067496 ⟸ ENSRNOT00000072160 |
RefSeq Acc Id: | XP_038939904 ⟸ XM_039083976 |
- Peptide Label: | isoform X2 |
- UniProtKB: | M0RD05 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | ENSRNOP00000088980 ⟸ ENSRNOT00000110411 |
RefSeq Acc Id: | ENSRNOP00000086582 ⟸ ENSRNOT00000109252 |
RefSeq Acc Id: | XP_063123585 ⟸ XM_063267515 |
- Peptide Label: | isoform X3 |
- UniProtKB: | A0A8I6AAZ1 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_063123583 ⟸ XM_063267513 |
- Peptide Label: | isoform X1 |
RefSeq Acc Id: | XP_063123584 ⟸ XM_063267514 |
- Peptide Label: | isoform X1 |
RefSeq Acc Id: | XP_063123586 ⟸ XM_063267516 |
- Peptide Label: | isoform X5 |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-M0RD05-F1-model_v2 | AlphaFold | M0RD05 | 1-154 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
RGD ID: | 13696791 | ||||||||
Promoter ID: | EPDNEW_R7315 | ||||||||
Type: | multiple initiation site | ||||||||
Name: | Ap1s3_1 | ||||||||
Description: | adaptor-related protein complex 1, sigma 3 subunit | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
Experiment Methods: | Single-end sequencing. | ||||||||
Position: |
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Database | Acc Id | Source(s) |
AGR Gene | RGD:1311772 | AgrOrtholog |
BioCyc Gene | G2FUF-27011 | BioCyc |
Ensembl Genes | ENSRNOG00000049873 | Ensembl, ENTREZGENE, UniProtKB/TrEMBL |
Ensembl Transcript | ENSRNOT00000072160.2 | UniProtKB/TrEMBL |
ENSRNOT00000109252.1 | UniProtKB/TrEMBL | |
ENSRNOT00000110411.1 | UniProtKB/TrEMBL | |
Gene3D-CATH | 3.30.450.60 | UniProtKB/TrEMBL |
InterPro | AP1_sigma | UniProtKB/TrEMBL |
AP_complex_ssu | UniProtKB/TrEMBL | |
AP_mu_sigma_su | UniProtKB/TrEMBL | |
Clathrin_sm-chain_CS | UniProtKB/TrEMBL | |
Longin-like_dom | UniProtKB/TrEMBL | |
NCBI Gene | Ap1s3 | ENTREZGENE |
PANTHER | AP-1 COMPLEX SUBUNIT SIGMA-3 | UniProtKB/TrEMBL |
PTHR11753 | UniProtKB/TrEMBL | |
Pfam | Clat_adaptor_s | UniProtKB/TrEMBL |
PhenoGen | Ap1s3 | PhenoGen |
PIRSF | AP_complex_sigma | UniProtKB/TrEMBL |
PROSITE | CLAT_ADAPTOR_S | UniProtKB/TrEMBL |
RatGTEx | ENSRNOG00000049873 | RatGTEx |
Superfamily-SCOP | Longin_like | UniProtKB/TrEMBL |
UniProt | A0A8I6A9X3_RAT | UniProtKB/TrEMBL |
A0A8I6AAZ1 | ENTREZGENE, UniProtKB/TrEMBL | |
M0RD05 | ENTREZGENE, UniProtKB/TrEMBL |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2021-03-09 | Ap1s3 | adaptor related protein complex 1 subunit sigma 3 | LOC108351958 | uncharacterized LOC108351958 | Data merged from RGD:11457835 | 737654 | PROVISIONAL |
2018-05-03 | Ap1s3 | adaptor related protein complex 1 subunit sigma 3 | Ap1s3 | adaptor-related protein complex 1, sigma 3 subunit | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2016-08-02 | LOC108351958 | uncharacterized LOC108351958 | Symbol and Name status set to provisional | 70820 | PROVISIONAL | ||
2012-07-31 | Ap1s3 | adaptor-related protein complex 1, sigma 3 subunit | LOC100360009 | adaptor-related protein complex AP-1, sigma 3-like | Data merged from RGD:2322936 | 737654 | APPROVED |
2012-07-05 | Ap1s3 | adaptor-related protein complex 1, sigma 3 subunit | Ap1s3 | adaptor-related protein complex 1, sigma 3 subunit | Gene reactivated at release of RGSC5.0 assembly | 2298974 | REACTIVATED |
2010-05-06 | LOC100360009 | adaptor-related protein complex AP-1, sigma 3-like | Symbol and Name status set to provisional | 70820 | PROVISIONAL | ||
2008-04-30 | Ap1s3 | adaptor-related protein complex 1, sigma 3 subunit | Ap1s3_predicted | adaptor-related protein complex 1, sigma 3 subunit (predicted) | 'predicted' is removed | 2292626 | APPROVED |
2005-01-12 | Ap1s3_predicted | adaptor-related protein complex 1, sigma 3 subunit (predicted) | Symbol and Name status set to approved | 70820 | APPROVED |