Cdh6 (cadherin 6) - Rat Genome Database

Name: Cdh6
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Cdh6 (cadherin 6) Rattus norvegicus

Analyze

Symbol:

Cdh6

Name:

cadherin 6

RGD ID:

2322

Description:

Predicted to enable cadherin binding activity and calcium ion binding activity. Involved in female gonad development. Predicted to be located in cell junction; nucleoplasm; and plasma membrane. Predicted to be part of catenin complex. Predicted to be active in adherens junction and glutamatergic synapse. Orthologous to human CDH6 (cadherin 6); INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

Cadherin 6 (K-cadherin); cadherin 6, type 2, K-cadherin; cadherin-6; K-cadherin; KCAD; kidney cadherin

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CDH6 (cadherin 6)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther
Mus musculus (house mouse):	Cdh6 (cadherin 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Cdh6 (cadherin 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	CDH6 (cadherin 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	CDH6 (cadherin 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Cdh6 (cadherin 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	CDH6 (cadherin 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	CDH6 (cadherin 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Cdh6 (cadherin 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	CDH10 (cadherin 10)	HGNC	OrthoDB
Homo sapiens (human):	CDH9 (cadherin 9)	HGNC	OrthoDB
Alliance orthologs ³
Mus musculus (house mouse):	Cdh6 (cadherin 6)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	CDH6 (cadherin 6)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	cdh6 (cadherin 6)	Alliance	DIOPT (Hieranoid\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	cdh10a (cadherin 10, type 2a (T2-cadherin))	Alliance	DIOPT (InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	cdh6	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	63,801,630 - 63,952,309 (-)	NCBI		GRCr8
mRatBN7.2	2	62,079,139 - 62,225,298 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	62,079,137 - 62,225,228 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	69,209,415 - 69,355,815 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	67,332,120 - 67,478,319 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	62,333,575 - 62,479,976 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	63,100,723 - 63,246,618 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	63,101,739 - 63,166,509 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	81,448,794 - 81,594,432 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	62,547,961 - 62,703,034 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	62,476,190 - 62,631,267 (-)	NCBI
Celera	2	56,475,456 - 56,620,253 (+)	NCBI		Celera
Cytogenetic Map	2	q16	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Cachexia (ISO)

genetic disease (ISO)

Neurodevelopmental Disorders (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(25R)-cholest-5-ene-3beta,26-diol (ISO)

17alpha-ethynylestradiol (EXP,ISO)

17beta-estradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (EXP)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

26-hydroxycholesterol (ISO)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-sulfonyldiphenol (ISO)

5-fluorouracil (ISO)

8-Br-cAMP (ISO)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

alendronic acid (EXP)

all-trans-retinoic acid (ISO)

ammonium chloride (EXP)

amosite asbestos (ISO)

antirheumatic drug (ISO)

aristolochic acid A (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

butanal (ISO)

CGP 52608 (ISO)

clofibrate (ISO)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

dimethylarsinous acid (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

entinostat (ISO)

ethanol (ISO)

formaldehyde (ISO)

fulvestrant (ISO)

furan (EXP)

genistein (ISO)

mercury dibromide (ISO)

methylmercury chloride (ISO)

N,N-diethyl-m-toluamide (EXP)

nickel atom (ISO)

niclosamide (ISO)

ozone (ISO)

p-chloromercuribenzoic acid (ISO)

paracetamol (ISO)

perfluorohexanesulfonic acid (ISO)

permethrin (EXP)

phenylmercury acetate (ISO)

pirinixic acid (ISO)

potassium chromate (ISO)

progesterone (ISO)

raloxifene (EXP)

resveratrol (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

temozolomide (ISO)

thalidomide (ISO)

trichloroethene (EXP)

trichostatin A (ISO)

triclosan (ISO)

valproic acid (ISO)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adherens junction organization (IBA,IEA)

calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (IBA,IEA,TAS)

cell migration (IBA)

cell morphogenesis (IBA,IEA)

cell-cell adhesion mediated by cadherin (IBA,IEA)

cell-cell junction assembly (IBA,IEA)

female gonad development (IEP)

homophilic cell adhesion via plasma membrane adhesion molecules (IEA)

Notch signaling pathway (IEA,ISO)

synaptic membrane adhesion (IBA,IEA,ISO)

Cellular Component

adherens junction (IBA,IEA)

catenin complex (IBA,IEA)

cell junction (ISO)

glutamatergic synapse (IEA,ISO)

nucleoplasm (IEA,ISO)

plasma membrane (IEA,ISO)

synapse (ISO)

Molecular Function

beta-catenin binding (IBA)

cadherin binding (IBA,IEA)

calcium ion binding (IBA,IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Multiple cadherin superfamily members with unique expression profiles are produced in rat testis.	Johnson KJ, etal., Endocrinology 2000 Feb;141(2):675-83.
4.	Expression and localization of P-, K-, and OB-cadherin in the prepubertal rat ovary.	Machell NH, etal., Mol Reprod Dev 2002 Feb;61(2):142-54.
5.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
6.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
7.	GOA pipeline	RGD automated data pipeline
8.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
10.	Isolation of complementary DNA encoding K-cadherin, a novel rat cadherin preferentially expressed in fetal kidney and kidney carcinoma.	Xiang YY, etal., Cancer Res 1994 Jun 1;54(11):3034-41.

Additional References at PubMed

PMID:11150865	PMID:12139922	PMID:23117660	PMID:23376485

Genomics

Comparative Map Data

Cdh6
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	63,801,630 - 63,952,309 (-)	NCBI		GRCr8
mRatBN7.2	2	62,079,139 - 62,225,298 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	62,079,137 - 62,225,228 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	69,209,415 - 69,355,815 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	67,332,120 - 67,478,319 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	62,333,575 - 62,479,976 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	63,100,723 - 63,246,618 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	63,101,739 - 63,166,509 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	81,448,794 - 81,594,432 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	62,547,961 - 62,703,034 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	62,476,190 - 62,631,267 (-)	NCBI
Celera	2	56,475,456 - 56,620,253 (+)	NCBI		Celera
Cytogenetic Map	2	q16	NCBI

CDH6
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	31,193,686 - 31,329,146 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	31,193,686 - 31,329,146 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	31,193,793 - 31,329,253 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	31,229,553 - 31,360,994 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	5	31,229,552 - 31,360,994	NCBI
Celera	5	31,074,550 - 31,205,743 (+)	NCBI		Celera
Cytogenetic Map	5	p13.3	NCBI
HuRef	5	31,162,140 - 31,297,610 (+)	NCBI		HuRef
CHM1_1	5	31,194,916 - 31,330,813 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	5	31,307,253 - 31,442,732 (+)	NCBI		T2T-CHM13v2.0

Cdh6
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	13,028,785 - 13,176,493 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	13,028,787 - 13,173,761 (-)	Ensembl		GRCm39 Ensembl
GRCm38	15	13,028,699 - 13,176,407 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	13,028,701 - 13,173,675 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	15	12,963,955 - 13,103,394 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	15	12,978,925 - 13,036,602 (-)	NCBI		MGSCv36	mm8
Celera	15	12,808,206 - 12,945,380 (-)	NCBI		Celera
Cytogenetic Map	15	A1	NCBI
cM Map	15	6.11	NCBI

Cdh6
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955426	17,187,197 - 17,311,186 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955426	17,187,191 - 17,316,730 (+)	NCBI	ChiLan1.0	ChiLan1.0

CDH6
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	78,986,650 - 79,126,446 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	77,140,291 - 77,280,100 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	79,013,970 - 79,152,645 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	84,398,468 - 84,529,567 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	84,398,474 - 84,456,013 (-)	Ensembl	panpan1.1		panPan2

CDH6
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	4	75,950,999 - 75,999,250 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	4	75,950,999 - 75,961,779 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	4	75,581,781 - 75,637,173 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	4	76,509,374 - 76,565,038 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	4	76,514,925 - 76,565,306 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	4	76,203,034 - 76,258,370 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	4	76,332,328 - 76,387,656 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	4	76,860,858 - 76,916,322 (-)	NCBI		UU_Cfam_GSD_1.0

Cdh6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	221,968,561 - 222,092,145 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936518	9,283,459 - 9,334,722 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936518	9,280,194 - 9,403,320 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CDH6
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	16	17,531,952 - 17,660,079 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	16	17,531,862 - 17,660,081 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	16	18,351,336 - 18,480,953 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CDH6
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	4	30,457,589 - 30,594,066 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	4	30,457,718 - 30,592,105 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666071	20,688,543 - 20,828,480 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cdh6
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624759	23,166,122 - 23,305,898 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624759	23,160,049 - 23,305,922 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Cdh6
846 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	573
Count of miRNA genes:	264
Interacting mature miRNAs:	330
Transcripts:	ENSRNOT00000018246
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
61355	Bp36	Blood pressure QTL 36	2.9		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	2	5873687	102844969	Rat
1357990	Ael1	Aortic elastin QTL 1	3.1	0.00091	aorta elastin amount (VT:0003905)	aortic elastin	2	19076825	64076825	Rat
731167	Glom4	Glomerulus QTL 4	2.4	0.0082	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	2	20304672	65304672	Rat
2300168	Bmd47	Bone mineral density QTL 47	6.6	0.0001	femur mineral mass (VT:0010011)	bone mineral density (CMO:0001226)	2	20662448	65662448	Rat
10402051	Gdil2	Gastrointestinal dilation QTL 2			enteric ganglion morphology trait (VT:0001045)	length of intestine affected by colonic aganglionosis to total length of colon ratio (CMO:0001836)	2	24903853	74786777	Rat
1302794	Stl27	Serum triglyceride level QTL 27	4.4	0.0001	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	2	25413423	143657569	Rat
1358894	Kidm24	Kidney mass QTL 24	4.03		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	25413423	157142209	Rat
1358899	Kidm23	Kidney mass QTL 23	3.88		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	25413423	157142209	Rat
1358901	Cm38	Cardiac mass QTL 38	2		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	157142209	Rat
1358904	Cm39	Cardiac mass QTL 39	2.26		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	157142209	Rat
1358910	Kidm27	Kidney mass QTL 27	5.77		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	25413423	157142209	Rat
1358911	Kidm28	Kidney mass QTL 28	5.42		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	25413423	157142209	Rat
1358913	Cm41	Cardiac mass QTL 41	2.73		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	203928301	Rat
1358917	Cm42	Cardiac mass QTL 42	2.82		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	203928301	Rat
1358887	Bw50	Body weight QTL 50	2.39		body mass (VT:0001259)	body weight (CMO:0000012)	2	25413652	157142078	Rat
1358908	Bw49	Body weight QTL 49	3.36		body mass (VT:0001259)	body weight (CMO:0000012)	2	25413652	157142078	Rat
1354617	Bp240	Blood pressure QTL 240	4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	26917817	81754745	Rat
1354617	Bp240	Blood pressure QTL 240	4		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	26917817	81754745	Rat
1354617	Bp240	Blood pressure QTL 240	4		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	26917817	81754745	Rat
1354603	Bp243	Blood pressure QTL 243	3.9		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	26917817	127469484	Rat
2290453	Scl55	Serum cholesterol level QTL 55	2.83		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	2	26917817	136917119	Rat
9590095	Sffal3	Serum free fatty acids level QTL 3	6.78	0.001	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	2	27157160	72157160	Rat
10755434	Coatc7	Coat color QTL 7		0.04794	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	2	30648065	75648065	Rat
10755436	Coatc8	Coat color QTL 8		0.02431	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	2	35023117	80023117	Rat
61371	Edpm1	Estrogen-dependent pituitary mass QTL 1	4	0.05	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	2	35134841	88029593	Rat
70174	BpQTLCluster2	Blood pressure QTL cluster 2	4.24		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	40067944	102785628	Rat
70174	BpQTLCluster2	Blood pressure QTL cluster 2	4.24		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	40067944	102785628	Rat
70174	BpQTLCluster2	Blood pressure QTL cluster 2	4.24		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	40067944	102785628	Rat
70174	BpQTLCluster2	Blood pressure QTL cluster 2	4.24		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	2	40067944	102785628	Rat
70174	BpQTLCluster2	Blood pressure QTL cluster 2	4.24		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	2	40067944	102785628	Rat
2293835	Kiddil5	Kidney dilation QTL 5	3.8		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	2	42804607	157142209	Rat
2293843	Kiddil6	Kidney dilation QTL 6	3.1		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	2	42804607	182042367	Rat
1298074	Bp164	Blood pressure QTL 164		0.003	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	42804607	202447032	Rat
1298085	Bp165	Blood pressure QTL 165		0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	42804607	202447032	Rat
61467	Bp14	Blood pressure QTL 14	2.2		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	43154682	202446871	Rat
61467	Bp14	Blood pressure QTL 14	2.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	43154682	202446871	Rat
2293676	Bmd19	Bone mineral density QTL 19	10.7	0.0001	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	2	43162366	111362592	Rat
2293682	Bmd24	Bone mineral density QTL 24	8.9	0.0001	femur mineral mass (VT:0010011)	compact volumetric bone mineral density (CMO:0001730)	2	43162366	111362592	Rat
2293671	Bss44	Bone structure and strength QTL 44	10.97	0.0001	lumbar vertebra morphology trait (VT:0010494)	lumbar vertebra cortical cross-sectional area (CMO:0001690)	2	43162366	148478373	Rat
631208	Bw1	Body weight QTL1	5.09		mesenteric fat pad mass (VT:0010427)	mesenteric fat pad weight to body weight ratio (CMO:0000654)	2	43171017	83575226	Rat
1354601	Slep1	Serum leptin concentration QTL 1	5.39		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	2	43171017	184114403	Rat
631266	Bp132	Blood pressure QTL 132		0.0005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	46123260	202447032	Rat
1354592	Rf50	Renal function QTL 50	3.5		urine output (VT:0003620)	timed urine volume (CMO:0000260)	2	53822747	74786777	Rat
1331760	Bp206	Blood pressure QTL 206	3.62454		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	56043031	202447032	Rat
6480225	Gdil1	Gastrointestinal dilation QTL 1			enteric ganglion morphology trait (VT:0001045)	length of intestine affected by colonic aganglionosis to total length of colon ratio (CMO:0001836)	2	56660879	74786777	Rat
1582246	Cm60	Cardiac mass QTL 60	5.8		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	57605612	76539510	Rat
1558648	Smcn1	Smooth muscle cell number QTL 1		0.039	blood vessel smooth muscle cell quantity (VT:0010525)	aorta smooth muscle cell count per unit vessel length (CMO:0001646)	2	59134147	127460910	Rat
5684990	Bmd82	Bone mineral density QTL 82	2.8		tibia mineral mass (VT:1000283)	bone mineral content (CMO:0001554)	2	59324377	103795077	Rat
5684996	Bmd85	Bone mineral density QTL 85	4.7	0.024	tibia mineral mass (VT:1000283)	bone mineral density (CMO:0001226)	2	59324377	103795077	Rat
61438	Cia7	Collagen induced arthritis QTL 7	4.6	0.0001	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	2	59324377	141596857	Rat
631500	Bp99	Blood pressure QTL 99	2.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	59324719	102755241	Rat
1578777	Stresp15	Stress response QTL 15	2	0.05	blood aldosterone amount (VT:0005346)	plasma aldosterone level (CMO:0000551)	2	59846005	104846005	Rat

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium									56	29	21
Low		40	25	12	15	12	7	7	18	6	17	8	7
Below cutoff	2	3	26	23	4	23	1	4			3	3	1

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_012927	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281354	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281355	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF110023	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF177678	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	D25290	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ219032	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000018246 ⟹ ENSRNOP00000018246

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	62,079,137 - 62,225,228 (-)	Ensembl
Rnor_6.0 Ensembl	2	63,101,739 - 63,166,509 (-)	Ensembl

RefSeq Acc Id:

NM_012927 ⟹ NP_037059

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	63,806,135 - 63,952,287 (-)	NCBI
mRatBN7.2	2	62,079,139 - 62,225,298 (-)	NCBI
Rnor_6.0	2	63,100,723 - 63,246,618 (-)	NCBI
Rnor_5.0	2	81,448,794 - 81,594,432 (+)	NCBI
RGSC_v3.4	2	62,547,961 - 62,703,034 (-)	RGD
Celera	2	56,475,456 - 56,620,253 (+)	NCBI

Sequence:

show sequence

CCTGGGCGAGTGGCAGGGTGTCCCCAGGAGCCGGAAGGCAAACAGAGATACCCTCTGAAAGCCA
AGCAGAGAACATTAAGGAAGAAAGGAGGAATGAGCCTGGGTCTGGTGCGGTGAAAAGAGACGCA
TTAAGGAAAGGGGAACTCACAACCCAGACGCTCCACTGCCAGCCTTGCCATCAGCATGAGAACT
TACCGGTACTTCTTGCTGCTCTTTTGGGTCGGCCAGCCCTACCCAACTTTCTCAAACCCGTTAT
CTAAAAGGACTAGTGGCTTCCCAGCAAAGAGGAGGGCCCTGGAGCTCTCTGCCAACAGCAGGAA
TGAGCTGAGCCGTTCAAAAAGGAGTTGGATGTGGAATCAGTTCTTCCTCCTGGAGGAATACACG
GGATCAGATTATCAGTACGTCGGCAAGTTACATTCAGACCAGGATAGAGGAGATGGATCACTTA
AATATATCCTTTCAGGAGATGGAGCGGGAGATCTCTTCATTATCAATGAAAACACAGGCGACAT
ACAAGCCACCAAGAGGCTGGACAGGGAAGAGAAACCCGTTTACATCCTTCGAGCCCAAGCTATC
AACAGAAGGACAGGGAGACCCGTCGAGCCTGAGTCTGAATTCATCATCAAGATCCATGACATCA
ATGATAATGAGCCAATATTCACCAAGGATGTTTACACAGCCACAGTCCCCGAGATGGCAGATGT
CGGAACATTTGTAGTCCAAGTCACAGCAACTGATGCCGATGACCCGACGTACGGGAACAGTGCT
AAAGTCGTGTACAGCATCCTGCAGGGACAGCCCTACTTTTCAGTGGAGTCGGAAACAGGTATCA
TCAAGACAGCGTTGCTCAACATGGATCGAGAAAACAGAGAGCAGTACCAAGTGGTGATTCAGGC
CAAGGACATGGGCGGCCAGATGGGAGGACTGTCGGGGACCACGACCGTGAACATCACACTGACA
GATGTCAATGACAATCCTCCTCGCTTCCCCCAGAGTACCTATCAGTTTAAGACTCCCGAGTCTT
CTCCACCAGGAACACCAATTGGCAGGATCAAAGCCAGTGATGCTGATGTGGGAGAAAATGCAGA
GATCGAGTACAGCATCACAGACGGTGAGGGACATGATATGTTTGACGTCATCACCGACCAGGAA
ACCCAGGAAGGGATTATAACTGTCAAAAAGCTCTTGGATTTTGAAAAGAAGAGAGTGTACACCC
TCAAGGTGGAAGCCTCCAATCCCCACATCGAACCCCGATTTCTCTACCTGGGTCCGTTCAAAGA
CTCGGCCACAGTGAGAATCGTGGTAGATGACGTAGATGAACCTCCTGTCTTCAGCAAACCGGCC
TACATCCTACAGATACGAGAGGATGCTCAGATAAACACAACCATAGGCTCTGTCGCAGCTCAGG
ATCCTGACGCTGCCAGGAATCCTGTCAAGTACTCGGTGGATAGACACACAGATATGGACAGGAT
ATTCAACATTGATTCTGGAAATGGCTCCATTTTTACATCAAAACTTCTCGACCGGGAAACGCTG
TTGTGGCATAACATCACAGTGATAGCAACGGAGATTAATAATCCAAAGCAAAGCAGCCGCGTGC
CTCTATATATTAAAGTTCTCGACGTCAATGACAATGCCCCAGAATTTGCTGAGTTCTATGAAAC
TTTTGTCTGTGAAAAAGCAAAGGCGGATCAGCTGATTCAGACCCTGCACGCTGTTGACAAGGAT
GATCCTTACAGTGGACACCAATTCTCCTTCTCTTTGGCCCCAGAAGCAGCCAGTGGCTCTAATT
TTACCATACAAGACAACAAAGACAACACTGCAGGGATCCTAACTCGGAAAAATGGCTATAACAG
ACACGAGATGAGCACTTATCTCCTGCCGGTGGTCATTTCAGACAACGACTACCCAGTCCAAAGC
AGCACTGGGACAGTGACTGTCCGGGTCTGTGCATGTGACCACCATGGAAACATGCAGTCCTGCC
ACGCCGAGGCCCTCATCCACCCCACAGGGCTGAGCACAGGGGCTCTGGTGGCCATCCTTCTGTG
CATCGTGATCCTACTAGTGACAGTGGTGCTGTTCGCAGCTCTGAGGCGGCAGCGAAAGAAAGAG
CCTTTGATCATTTCCAAAGAGGACATCAGAGACAACATTGTCAGTTACAACGACGAAGGTGGCG
GAGAGGAAGACACCCAGGCCTTTGATATCGGAACCCTGAGGAACCCTAAGCCATGGAGACAGCA
ATCGCGCAGGGACATGGTGCCTGAAGCTCTTTTTCTACCACGGCGGACTCCAACAGCTCGTGAC
AACACGGATGTCAGAGATTTCATTAGCCAAAGGTTAAGGAAAATGAACACGGACCCAACAGCCC
CTCCCTACGACTCCTTGGCCACCTATGCCTACGAAGGCACTGGCTCGGTGGCCGACTCCCTGAG
CTCACTAGAATCAGTGACCACAGATGGAGACCAAGATTATGGCTATTTGAGTGACTGGGGCCCT
CGGTTCAAAAAGCTGGCAGATATGTACGGAGGGATGGACAGTGACAAAGACTCCTAATCTGTTG
CCTTTTCATTTTCCAATATGACACTGGAATATGTGACGTGGCTATTCCTTTCTATTTATCCACT
ATTCCGTGAGGGGTTCTCCGTTGTACCCGTTCCAAAAGTCAATGGCTGCAGTCCGTGTGGATCC
AATGTTAGAGACTTTTTTCTAGTACACTTTTATGAGCTTCTAAGAGGCAAATTTTTATTTTTTA
GTTCATGCAGTTAACCAAGTTAGCCCAGCAGGCACGCTGCGGGAGGAGAGGAAGGAACGGCGTT
TTTCCCGTGTTCCCCTTAGAGCAGGTTGGCCACGCCCCTTACTGCTGGCCTAGACTCTACTTTG
GTTCACGGCCTCCATTCCGCTGAATGCTCCAAATGTACATTTCACATGCTACACATGCTAATGA
AGAAGGGATCATACTTTGATGATTAAAAATATAGTTTTAGTATTTAAAAGGGGGGAGGGAACAA
TTGGGAAATTGATCCTGGTCTATCAGTTGTCAAGGAGATAATTAACTGTGAAGGGGTTTGTAAG
GATATGCGTGTGTCAAGGAATATAAAGTGGGGCATCCTGTCTGTGCTGGAAGGGGTGTTTCTGG
CATCAACAAATACTCGTAATGCTGAATCCTTCCATGTTCTAAGATGGCTTAGAAGCAAATCAAG
TGGTATCATGTTCAAAGACAGTAACGAAAGACAGGGCTGTGTTCCCTGACGAGATTTTGTTGCA
TGTGATAAACAGATGCTTCACCATCATGCCAAACAAAGGAAAAAAGAGAAATAGCTTTACAAAA
AAAAATTAACAAAGGACATATTTAGGGAATTTCAAGGTTTTGTACTACCAACAGTATCCCGGGT
CCCTTCATTCTTTCAACTATCAGTAAACTAATGAGAAGTAGGTCTAATCATATAAGCGTCCTTG
AGAGAATTTCCTGAGGCAAATGTTAACTCTTTGTCTGTAGTTGTTGTTACTATTATCCTACTAT
ACCTGAGTGTAGCAGTGTGAAGTACAATAATTCATATTCTTCAAAAAAAGAAAAAAAAAGGATC
CGCGGCCGCC

hide sequence

RefSeq Acc Id:

XM_063281354 ⟹ XP_063137424

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	63,801,630 - 63,951,994 (-)	NCBI

RefSeq Acc Id:

XM_063281355 ⟹ XP_063137425

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	63,807,504 - 63,952,309 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_037059	(Get FASTA)	NCBI Sequence Viewer
	XP_063137424	(Get FASTA)	NCBI Sequence Viewer
	XP_063137425	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAF87053	(Get FASTA)	NCBI Sequence Viewer
	BAA04975	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000018246
	ENSRNOP00000018246.8
GenBank Protein	P55280	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_037059 ⟸ NM_012927
- Peptide Label:	precursor
- UniProtKB:	P55280 (UniProtKB/Swiss-Prot), F1LQP8 (UniProtKB/TrEMBL), A6KJN4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MRTYRYFLLLFWVGQPYPTFSNPLSKRTSGFPAKRRALELSANSRNELSRSKRSWMWNQFFLLE EYTGSDYQYVGKLHSDQDRGDGSLKYILSGDGAGDLFIINENTGDIQATKRLDREEKPVYILRA QAINRRTGRPVEPESEFIIKIHDINDNEPIFTKDVYTATVPEMADVGTFVVQVTATDADDPTYG NSAKVVYSILQGQPYFSVESETGIIKTALLNMDRENREQYQVVIQAKDMGGQMGGLSGTTTVNI TLTDVNDNPPRFPQSTYQFKTPESSPPGTPIGRIKASDADVGENAEIEYSITDGEGHDMFDVIT DQETQEGIITVKKLLDFEKKRVYTLKVEASNPHIEPRFLYLGPFKDSATVRIVVDDVDEPPVFS KPAYILQIREDAQINTTIGSVAAQDPDAARNPVKYSVDRHTDMDRIFNIDSGNGSIFTSKLLDR ETLLWHNITVIATEINNPKQSSRVPLYIKVLDVNDNAPEFAEFYETFVCEKAKADQLIQTLHAV DKDDPYSGHQFSFSLAPEAASGSNFTIQDNKDNTAGILTRKNGYNRHEMSTYLLPVVISDNDYP VQSSTGTVTVRVCACDHHGNMQSCHAEALIHPTGLSTGALVAILLCIVILLVTVVLFAALRRQR KKEPLIISKEDIRDNIVSYNDEGGGEEDTQAFDIGTLRNPKPWRQQSRRDMVPEALFLPRRTPT ARDNTDVRDFISQRLRKMNTDPTAPPYDSLATYAYEGTGSVADSLSSLESVTTDGDQDYGYLSD WGPRFKKLADMYGGMDSDKDS hide sequence

RefSeq Acc Id:

ENSRNOP00000018246 ⟸ ENSRNOT00000018246

RefSeq Acc Id:	XP_063137424 ⟸ XM_063281354
- Peptide Label:	isoform X1
- UniProtKB:	A6KJN4 (UniProtKB/TrEMBL), F1LQP8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063137425 ⟸ XM_063281355
- Peptide Label:	isoform X2

Protein Domains

Cadherin

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P55280-F1-model_v2	AlphaFold	P55280	1-789	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:2322	AgrOrtholog
BioCyc Gene	G2FUF-54034	BioCyc
Ensembl Genes	ENSRNOG00000013535	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000018246	ENTREZGENE
	ENSRNOT00000018246.8	UniProtKB/TrEMBL
Gene3D-CATH	4.10.900.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Cadherins	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	Cadherin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Cadherin-like_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Cadherin-like_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Cadherin_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Cadherin_cytoplasmic-dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Catenin_binding_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:25409	UniProtKB/Swiss-Prot
NCBI Gene	25409	ENTREZGENE
PANTHER	CADHERIN-6	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR24027	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Cadherin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Cadherin_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Cdh6	PhenoGen
PRINTS	CADHERIN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	CADHERIN_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	CADHERIN_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000013535	RatGTEx
SMART	SM00112	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF49313	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A6KJN4	ENTREZGENE, UniProtKB/TrEMBL
	CADH6_RAT	UniProtKB/Swiss-Prot
	F1LQP8	ENTREZGENE, UniProtKB/TrEMBL
	P55280	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-01-26	Cdh6	cadherin 6	Cdh6	cadherin 6, type 2, K-cadherin	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2014-01-14	Cdh6	cadherin 6, type 2, K-cadherin	Cdh6	cadherin 6	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2002-11-06	Cdh6	cadherin 6		Cadherin 6 (K-cadherin)	Name updated	625702	APPROVED
2002-06-10	Cdh6	Cadherin 6 (K-cadherin)			Symbol and Name status set to approved	70586	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD