Ypel1 (yippee-like 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Ypel1 (yippee-like 1) Rattus norvegicus
Analyze
Symbol: Ypel1
Name: yippee-like 1
RGD ID: 2321291
Description: Orthologous to human YPEL1 (yippee like 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-methoxyethanol; fenvalerate.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC100360867; yippee-like 1 (Drosophila)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81197,426,012 - 97,440,646 (-)NCBIGRCr8
mRatBN7.21183,921,799 - 83,936,409 (-)NCBImRatBN7.2mRatBN7.2
Rnor_6.01188,171,401 - 88,186,000 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1188,173,890 - 88,180,542 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01191,224,741 - 91,238,647 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41185,929,479 - 85,936,364 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1182,677,482 - 82,692,081 (-)NCBICelera
Cytogenetic Map11q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Ypel1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81197,426,012 - 97,440,646 (-)NCBIGRCr8
mRatBN7.21183,921,799 - 83,936,409 (-)NCBImRatBN7.2mRatBN7.2
Rnor_6.01188,171,401 - 88,186,000 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1188,173,890 - 88,180,542 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01191,224,741 - 91,238,647 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41185,929,479 - 85,936,364 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1182,677,482 - 82,692,081 (-)NCBICelera
Cytogenetic Map11q23NCBI
YPEL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382221,697,536 - 21,735,794 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2221,697,536 - 21,735,794 (-)EnsemblGRCh38hg38GRCh38
GRCh372222,051,825 - 22,090,083 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362220,381,825 - 20,420,071 (-)NCBINCBI36Build 36hg18NCBI36
Build 342220,376,381 - 20,414,625NCBI
Celera225,869,356 - 5,907,602 (-)NCBICelera
Cytogenetic Map22q11.21-q11.22NCBI
HuRef225,009,474 - 5,047,359 (-)NCBIHuRef
CHM1_12222,052,019 - 22,090,249 (-)NCBICHM1_1
T2T-CHM13v2.02222,111,014 - 22,149,275 (-)NCBIT2T-CHM13v2.0
Ypel1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391616,887,454 - 16,904,912 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1616,887,560 - 16,904,909 (+)EnsemblGRCm39 Ensembl
GRCm381617,070,139 - 17,087,048 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1617,069,696 - 17,087,045 (+)EnsemblGRCm38mm10GRCm38
MGSCv371617,070,404 - 17,086,781 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361616,983,874 - 17,000,251 (+)NCBIMGSCv36mm8
Celera1617,643,100 - 17,659,477 (+)NCBICelera
Cytogenetic Map16A3NCBI
cM Map1610.58NCBI
Ypel1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495544217,400,655 - 17,423,896 (+)NCBIChiLan1.0ChiLan1.0
YPEL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22331,242,950 - 31,281,211 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12233,791,680 - 33,829,957 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0223,820,354 - 3,858,632 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12220,306,577 - 20,340,767 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2220,306,577 - 20,340,773 (-)Ensemblpanpan1.1panPan2
YPEL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12630,967,997 - 30,992,111 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2630,968,334 - 30,992,334 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2630,925,222 - 30,949,224 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02632,373,733 - 32,398,278 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2632,371,581 - 32,398,278 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12630,420,895 - 30,446,850 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02630,044,434 - 30,070,539 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02631,134,454 - 31,161,039 (-)NCBIUU_Cfam_GSD_1.0
Ypel1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118140,769,878 - 140,795,692 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366191,958,370 - 1,981,350 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366191,958,370 - 1,984,182 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
YPEL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1450,190,798 - 50,208,256 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11450,190,641 - 50,208,732 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21453,641,158 - 53,656,696 (+)NCBISscrofa10.2Sscrofa10.2susScr3
YPEL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1194,378,483 - 4,409,498 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl194,400,451 - 4,409,228 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660852,589,654 - 2,623,792 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ypel1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247471,248,026 - 1,274,869 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247471,248,026 - 1,274,909 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ypel1
38 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:35
Count of miRNA genes:35
Interacting mature miRNAs:35
Transcripts:ENSRNOT00000002539
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)115445753486241447Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)115635142486241447Rat
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)116034659086241447Rat
634339Niddm50Non-insulin dependent diabetes mellitus QTL 503.32blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)116642214886241447Rat
1354593Stl12Serum triglyceride level QTL 123.36blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)116642214886241447Rat

Markers in Region
RH135247  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21183,927,311 - 83,927,509 (+)MAPPERmRatBN7.2
Rnor_6.01188,176,916 - 88,177,113NCBIRnor6.0
Rnor_5.01191,229,581 - 91,229,778UniSTSRnor5.0
RGSC_v3.41185,932,738 - 85,932,935UniSTSRGSC3.4
Celera1182,682,997 - 82,683,194UniSTS
RH 3.4 Map11733.22UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 22 5 4 1 4 58 20 38 1
Low 3 21 40 25 18 25 7 10 16 15 3 10 7
Below cutoff 10 10 10 1 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000002539   ⟹   ENSRNOP00000002539
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1188,173,890 - 88,180,542 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000085475   ⟹   ENSRNOP00000071004
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1188,173,890 - 88,177,448 (-)Ensembl
RefSeq Acc Id: NM_001426989   ⟹   NP_001413918
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81197,426,012 - 97,440,566 (-)NCBI
RefSeq Acc Id: XM_008768928   ⟹   XP_008767150
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81197,426,687 - 97,440,646 (-)NCBI
mRatBN7.21183,921,799 - 83,936,409 (-)NCBI
Rnor_6.01188,171,401 - 88,186,000 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063270226   ⟹   XP_063126296
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81197,426,687 - 97,440,645 (-)NCBI
RefSeq Acc Id: XM_063270227   ⟹   XP_063126297
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81197,426,687 - 97,440,646 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001413918 (Get FASTA)   NCBI Sequence Viewer  
  XP_008767150 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126296 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126297 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL77870 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_008767150   ⟸   XM_008768928
- Peptide Label: isoform X1
- UniProtKB: A6JSN7 (UniProtKB/TrEMBL),   A6K0A1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000002539   ⟸   ENSRNOT00000002539
RefSeq Acc Id: ENSRNOP00000071004   ⟸   ENSRNOT00000085475
RefSeq Acc Id: NP_001413918   ⟸   NM_001426989
- UniProtKB: A6JSN7 (UniProtKB/TrEMBL),   A6K0A1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126297   ⟸   XM_063270227
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063126296   ⟸   XM_063270226
- Peptide Label: isoform X2
Protein Domains
Yippee

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A9Y3-F1-model_v2 AlphaFold D4A9Y3 1-118 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2321291 AgrOrtholog
BioCyc Gene G2FUF-20566 BioCyc
Ensembl Genes ENSRNOG00000001858 Ensembl
InterPro Yippee UniProtKB/TrEMBL
  Yippee/Mis18/Cereblon UniProtKB/TrEMBL
  Yippee_fam UniProtKB/TrEMBL
KEGG Report rno:100360867 UniProtKB/TrEMBL
NCBI Gene 100360867 ENTREZGENE
PANTHER PROTEIN YIPPEE-LIKE 2 UniProtKB/TrEMBL
  PROTEIN YIPPEE-LIKE CG15309-RELATED UniProtKB/TrEMBL
Pfam Yippee-Mis18 UniProtKB/TrEMBL
PhenoGen Ypel1 PhenoGen
PROSITE YIPPEE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000001858 RatGTEx
UniProt A6JSN7 ENTREZGENE, UniProtKB/TrEMBL
  A6K0A1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-07-30 Ypel1  yippee-like 1  Ypel1  yippee-like 1 (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-08-09 Ypel1  yippee-like 1 (Drosophila)  LOC100360867  yippee-like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-05 LOC100360867  yippee-like 1      Symbol and Name status set to provisional 70820 PROVISIONAL