Gene: Rock1 (Rho-associated coiled-coil containing protein kinase 1) Rattus norvegicus
Symbol: Rock1
Name: Rho-associated coiled-coil containing protein kinase 1
Description: ENCODES a protein that exhibits GTP-Rho binding; protein serine/threonine kinase activity (ortholog); INVOLVED IN cytoskeleton organization; Rho protein signal transduction; actin cytoskeleton organization (ortholog); PARTICIPATES IN E-cadherin signaling pathway; eicosanoid signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; ASSOCIATED WITH Hypertrophy, Left Ventricular; Neoplasms, Germ Cell and Embryonal (ortholog); FOUND IN cytoskeleton (ortholog); lamellipodium (ortholog); plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; aldehydo-D-glucose
Type: protein-coding
Also known as: liver regeneration-related protein LRRG199; p150 RhoA-binding kinase ROK beta; p160 ROCK-1; P160Rock; Rho-associated coiled-coil forming kinase 1; Rho-associated kinase beta; rho-associated protein kinase 1; rho-associated, coiled-coil-containing protein kinase 1; rho-associated, coiled-coil-containing protein kinase I; ROCK-I
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0181,273,490 - 1,390,790 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.0181,316,022 - 1,433,175 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.4181,391,751 - 1,511,865 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1181,391,824 - 1,511,866 (-)NCBI
Celera181,001,677 - 1,120,847 (-)NCBI
Cytogenetic Map18p13NCBImapview

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Rock1
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 620424
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2016-09-13
Status: ACTIVE