Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-catechin | multiple interactions | ISO | LRRC2 (Homo sapiens) | 6480464 | [Catechin co-treated with Grape Seed Proanthocyanidins] results in decreased expression of LRRC2 mRNA | CTD | PMID:24763279 | 1-naphthyl isothiocyanate | increases expression | EXP | | 6480464 | 1-Naphthylisothiocyanate results in increased expression of LRRC2 mRNA | CTD | PMID:30723492 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Lrrc2 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin affects the methylation of LRRC2 intron] which results in decreased expression of LRRC2 mRNA and [Tetrachlorodibenzodioxin co-treated with Decitabine] results in increased expression of LRRC2 mRNA | CTD | PMID:15251184 and PMID:33017471 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of LRRC2 mRNA | CTD | PMID:32109520 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | LRRC2 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of LRRC2 mRNA | CTD | PMID:30096437 | 4,4'-sulfonyldiphenol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of LRRC2 mRNA | CTD | PMID:36041667 | 5-aza-2'-deoxycytidine | affects expression | ISO | LRRC2 (Homo sapiens) | 6480464 | Decitabine affects the expression of LRRC2 mRNA | CTD | PMID:17145863 | 5-aza-2'-deoxycytidine | increases expression | ISO | Lrrc2 (Mus musculus) | 6480464 | Decitabine results in increased expression of LRRC2 mRNA | CTD | PMID:15251184 | 5-aza-2'-deoxycytidine | multiple interactions | ISO | Lrrc2 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Decitabine] results in increased expression of LRRC2 mRNA | CTD | PMID:15251184 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of LRRC2 mRNA | CTD | PMID:24780913 and PMID:25825206 | acrylamide | decreases expression | EXP | | 6480464 | Acrylamide results in decreased expression of LRRC2 mRNA | CTD | PMID:28959563 | aflatoxin B1 | decreases expression | ISO | LRRC2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of LRRC2 mRNA | CTD | PMID:27153756 | aflatoxin B1 | increases methylation | ISO | LRRC2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of LRRC2 3' UTR | CTD | PMID:30157460 | aldrin | multiple interactions | ISO | LRRC2 (Homo sapiens) | 6480464 | [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of LRRC2 mRNA | CTD | PMID:28263720 | benzo[a]pyrene | decreases expression | ISO | Lrrc2 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of LRRC2 mRNA | CTD | PMID:22228805 | benzo[a]pyrene | decreases expression | ISO | LRRC2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of LRRC2 mRNA | CTD | PMID:32234424 | benzo[a]pyrene | increases methylation | ISO | LRRC2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of LRRC2 exon and Benzo(a)pyrene results in increased methylation of LRRC2 promoter | CTD | PMID:27901495 | benzo[a]pyrene | affects methylation | ISO | LRRC2 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of LRRC2 5' UTR | CTD | PMID:27901495 | benzo[a]pyrene | decreases methylation | ISO | LRRC2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of LRRC2 3' UTR | CTD | PMID:27901495 | benzo[a]pyrene diol epoxide I | increases expression | ISO | LRRC2 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:20382639 | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of LRRC2 gene | CTD | PMID:28505145 | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of LRRC2 mRNA | CTD | PMID:36041667 | bisphenol A | multiple interactions | ISO | LRRC2 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of LRRC2 gene | CTD | PMID:31601247 | bisphenol F | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of LRRC2 mRNA | CTD | PMID:36041667 | Cuprizon | increases expression | EXP | | 6480464 | Cuprizone results in increased expression of LRRC2 mRNA | CTD | PMID:26577399 and PMID:27523638 | cyclosporin A | increases expression | ISO | LRRC2 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of LRRC2 mRNA | CTD | PMID:27989131 | DDD | multiple interactions | ISO | LRRC2 (Homo sapiens) | 6480464 | [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of LRRC2 mRNA | CTD | PMID:28263720 | DDE | multiple interactions | ISO | LRRC2 (Homo sapiens) | 6480464 | [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of LRRC2 mRNA | CTD | PMID:28263720 | DDT | multiple interactions | ISO | LRRC2 (Homo sapiens) | 6480464 | [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of LRRC2 mRNA | CTD | PMID:28263720 | dieldrin | multiple interactions | ISO | LRRC2 (Homo sapiens) | 6480464 | [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of LRRC2 mRNA | CTD | PMID:28263720 | endrin | multiple interactions | ISO | LRRC2 (Homo sapiens) | 6480464 | [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of LRRC2 mRNA | CTD | PMID:28263720 | fluoranthene | multiple interactions | ISO | Lrrc2 (Mus musculus) | 6480464 | [1-methylanthracene co-treated with fluoranthene] results in increased expression of LRRC2 mRNA | CTD | PMID:28329830 | fluoranthene | increases expression | ISO | Lrrc2 (Mus musculus) | 6480464 | fluoranthene results in increased expression of LRRC2 mRNA | CTD | PMID:28329830 | folic acid | decreases expression | ISO | Lrrc2 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of LRRC2 mRNA | CTD | PMID:25629700 | fulvestrant | multiple interactions | ISO | LRRC2 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of LRRC2 gene | CTD | PMID:31601247 | gamma-hexachlorocyclohexane | multiple interactions | ISO | LRRC2 (Homo sapiens) | 6480464 | [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of LRRC2 mRNA | CTD | PMID:28263720 | genistein | decreases expression | ISO | Lrrc2 (Mus musculus) | 6480464 | Genistein results in decreased expression of LRRC2 mRNA | CTD | PMID:32186404 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of LRRC2 mRNA | CTD | PMID:33387578 | lipopolysaccharide | multiple interactions | ISO | LRRC2 (Homo sapiens) | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in decreased expression of LRRC2 mRNA | CTD | PMID:35811015 | niclosamide | increases expression | ISO | LRRC2 (Homo sapiens) | 6480464 | Niclosamide results in increased expression of LRRC2 mRNA | CTD | PMID:36318118 | paraquat | increases expression | EXP | | 6480464 | Paraquat results in increased expression of LRRC2 mRNA | CTD | PMID:32680482 | rotenone | increases expression | EXP | | 6480464 | Rotenone results in increased expression of LRRC2 mRNA | CTD | PMID:28374803 | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | LRRC2 (Homo sapiens) | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in decreased expression of LRRC2 mRNA | CTD | PMID:35811015 | serpentine asbestos | increases expression | ISO | LRRC2 (Homo sapiens) | 6480464 | Asbestos and Serpentine results in increased expression of LRRC2 mRNA | CTD | PMID:21148743 | silicon dioxide | increases expression | ISO | LRRC2 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of LRRC2 mRNA | CTD | PMID:25895662 | silicon dioxide | decreases expression | ISO | LRRC2 (Homo sapiens) | 6480464 | Silicon Dioxide results in decreased expression of LRRC2 mRNA | CTD | PMID:34973136 | silicon dioxide | increases methylation | ISO | LRRC2 (Homo sapiens) | 6480464 | Silicon Dioxide results in increased methylation of LRRC2 gene | CTD | PMID:34973136 | simvastatin | multiple interactions | ISO | LRRC2 (Homo sapiens) | 6480464 | [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of LRRC2 mRNA | CTD | PMID:28263720 | titanium dioxide | decreases expression | ISO | Lrrc2 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of LRRC2 mRNA | CTD | PMID:23557971 | titanium dioxide | increases expression | ISO | Lrrc2 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of LRRC2 mRNA | CTD | PMID:29264374 | valproic acid | decreases expression | ISO | Lrrc2 (Mus musculus) | 6480464 | Valproic Acid results in decreased expression of LRRC2 mRNA | CTD | PMID:21427059 | valproic acid | affects expression | ISO | LRRC2 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of LRRC2 mRNA | CTD | PMID:25979313 | valproic acid | increases methylation | ISO | LRRC2 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of LRRC2 gene | CTD | PMID:29154799 | |