Prr36 (proline rich 36) - Rat Genome Database

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Gene: Prr36 (proline rich 36) Rattus norvegicus
Analyze
Symbol: Prr36
Name: proline rich 36
RGD ID: 1566084
Description: Orthologous to human PRR36 (proline rich 36); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC501795; proline-rich protein 36; RGD1566084; similar to Hypothetical protein LOC73072
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8127,358,385 - 7,365,616 (-)NCBIGRCr8
mRatBN7.2122,560,533 - 2,567,766 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl122,560,536 - 2,567,742 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0122,579,154 - 2,586,126 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl122,579,887 - 2,585,233 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0124,731,815 - 4,740,990 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4121,578,243 - 1,583,773 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera124,376,194 - 4,383,164 (-)NCBICelera
Cytogenetic Map12p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Prr36
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8127,358,385 - 7,365,616 (-)NCBIGRCr8
mRatBN7.2122,560,533 - 2,567,766 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl122,560,536 - 2,567,742 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0122,579,154 - 2,586,126 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl122,579,887 - 2,585,233 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0124,731,815 - 4,740,990 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4121,578,243 - 1,583,773 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera124,376,194 - 4,383,164 (-)NCBICelera
Cytogenetic Map12p12NCBI
PRR36
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38197,868,719 - 7,874,390 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl197,868,719 - 7,874,390 (-)EnsemblGRCh38hg38GRCh38
GRCh37197,933,605 - 7,939,275 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36197,839,605 - 7,849,956 (-)NCBINCBI36Build 36hg18NCBI36
Celera197,804,893 - 7,810,545 (-)NCBICelera
Cytogenetic Map19p13.2NCBI
HuRef197,604,117 - 7,609,771 (-)NCBIHuRef
CHM1_1197,933,244 - 7,938,966 (-)NCBICHM1_1
T2T-CHM13v2.0197,869,675 - 7,875,346 (-)NCBIT2T-CHM13v2.0
Prr36
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3984,259,478 - 4,267,530 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl84,259,543 - 4,267,459 (-)EnsemblGRCm39 Ensembl
GRCm3884,209,478 - 4,217,530 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl84,209,543 - 4,217,459 (-)EnsemblGRCm38mm10GRCm38
MGSCv3784,209,543 - 4,217,312 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3684,209,543 - 4,217,312 (-)NCBIMGSCv36mm8
Celera84,410,067 - 4,417,656 (-)NCBICelera
Cytogenetic Map8A1.1NCBI
cM Map81.98NCBI
Prr36
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555631,378,893 - 1,383,597 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555631,377,887 - 1,383,597 (+)NCBIChiLan1.0ChiLan1.0
PRR36
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22012,552,327 - 12,558,259 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11911,669,511 - 11,675,441 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0197,170,792 - 7,176,453 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1198,022,421 - 8,027,575 (-)NCBIpanpan1.1PanPan1.1panPan2
PRR36
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12052,576,240 - 52,580,880 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2052,378,883 - 52,383,433 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02053,104,481 - 53,109,067 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2053,104,522 - 53,109,555 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12052,307,787 - 52,312,336 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02052,752,397 - 52,756,984 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02052,983,799 - 52,988,349 (-)NCBIUU_Cfam_GSD_1.0
Prr36
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118212,966,979 - 212,972,263 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365884,862,520 - 4,866,705 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRR36
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl271,323,641 - 71,329,204 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1271,323,776 - 71,329,221 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2271,725,033 - 71,727,139 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PRR36
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.167,324,004 - 7,330,500 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666081486,048 - 491,837 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Prr36
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624828850,086 - 864,336 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Prr36
29 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:58
Count of miRNA genes:28
Interacting mature miRNAs:29
Transcripts:ENSRNOT00000043197, ENSRNOT00000068586
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300174Bw15Body weight QTL 152.93body mass (VT:0001259)body weight loss (CMO:0001399)1219318387Rat
2312418Kidm41Kidney mass QTL 413.70.0001kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)12119611090Rat
10755457Coatc14Coat color QTL 140.01759coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)12122591684Rat
6893681Bw109Body weight QTL 1092.30.004body mass (VT:0001259)body weight (CMO:0000012)12123297788Rat
1581516Cm56Cardiac mass QTL 564.20.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)12129333307Rat
1598855Bp294Blood pressure QTL 2943.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12134851688Rat
7411660Foco28Food consumption QTL 2810.90.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
9590086Insglur6Insulin/glucose ratio QTL 618.970.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)12142110980Rat
8694179Bw150Body weight QTL 1502.90.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
7411586Foco5Food consumption QTL 55.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411595Foco9Food consumption QTL 940.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411545Bw128Body weight QTL 1285.20.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)12142110980Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12142450532Rat
737979Pia22Pristane induced arthritis QTL 2253.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12144465750Rat
634351Apr5Acute phase response QTL 56.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)12144503507Rat
2302042Pia38Pristane induced arthritis QTL 383.50.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)12144503507Rat
7243862Mcs30Mammary carcinoma susceptibility QTL 308.62mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)127977298525593Rat
634350Apr4Acute phase response QTL 46orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)12117200546172005Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 66 12 10
Low 3 26 13 6 9 6 8 14 28 4
Below cutoff 10 32 23 10 23 4 7 9 3 7 4

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000043197   ⟹   ENSRNOP00000041388
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl122,579,887 - 2,585,233 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000068586   ⟹   ENSRNOP00000063265
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl122,560,536 - 2,567,742 (-)Ensembl
Rnor_6.0 Ensembl122,579,887 - 2,585,233 (+)Ensembl
RefSeq Acc Id: XM_008769018   ⟹   XP_008767240
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8127,358,385 - 7,365,147 (-)NCBI
mRatBN7.2122,560,533 - 2,567,307 (-)NCBI
Rnor_6.0122,579,154 - 2,586,126 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017598471   ⟹   XP_017453960
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8127,358,385 - 7,365,478 (-)NCBI
mRatBN7.2122,560,533 - 2,567,632 (-)NCBI
Rnor_6.0122,579,482 - 2,586,126 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039089904   ⟹   XP_038945832
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8127,358,385 - 7,365,570 (-)NCBI
mRatBN7.2122,560,533 - 2,567,632 (-)NCBI
RefSeq Acc Id: XM_039089905   ⟹   XP_038945833
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8127,358,385 - 7,365,616 (-)NCBI
mRatBN7.2122,560,533 - 2,567,766 (-)NCBI
RefSeq Acc Id: XM_039089906   ⟹   XP_038945834
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8127,358,385 - 7,365,616 (-)NCBI
mRatBN7.2122,560,533 - 2,567,766 (-)NCBI
RefSeq Acc Id: XM_063271834   ⟹   XP_063127904
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8127,358,385 - 7,365,147 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_008767240   ⟸   XM_008769018
- UniProtKB: D3ZUH5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017453960   ⟸   XM_017598471
- UniProtKB: D3ZUH5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000041388   ⟸   ENSRNOT00000043197
RefSeq Acc Id: ENSRNOP00000063265   ⟸   ENSRNOT00000068586
RefSeq Acc Id: XP_038945834   ⟸   XM_039089906
- UniProtKB: D3ZUH5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038945833   ⟸   XM_039089905
- UniProtKB: D3ZUH5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038945832   ⟸   XM_039089904
- UniProtKB: D3ZUH5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063127904   ⟸   XM_063271834
- UniProtKB: D3ZUH5 (UniProtKB/TrEMBL)
Protein Domains
BTB/POZ

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZUH5-F1-model_v2 AlphaFold D3ZUH5 1-1079 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1566084 AgrOrtholog
BioCyc Gene G2FUF-20354 BioCyc
Ensembl Genes ENSRNOG00000028892 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000068586.5 UniProtKB/TrEMBL
InterPro DUF4596 UniProtKB/TrEMBL
KEGG Report rno:501795 UniProtKB/TrEMBL
NCBI Gene 501795 ENTREZGENE
PANTHER PROLINE-RICH PROTEIN 36 UniProtKB/TrEMBL
  UNCHARACTERIZED UniProtKB/TrEMBL
Pfam DUF4596 UniProtKB/TrEMBL
PhenoGen Prr36 PhenoGen
RatGTEx ENSRNOG00000028892 RatGTEx
UniProt D3ZUH5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-10-22 Prr36  proline rich 36  RGD1566084  similar to Hypothetical protein LOC73072  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1566084  similar to Hypothetical protein LOC73072   RGD1566084_predicted  similar to Hypothetical protein LOC73072 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1566084_predicted  similar to Hypothetical protein LOC73072 (predicted)  LOC501795  similar to Hypothetical protein LOC73072  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC501795  similar to Hypothetical protein LOC73072      Symbol and Name status set to provisional 70820 PROVISIONAL