Gene: Alpl (alkaline phosphatase, liver/bone/kidney) Rattus norvegicus
Symbol: Alpl
Name: alkaline phosphatase, liver/bone/kidney
Description: ENCODES a protein that exhibits alkaline phosphatase activity; pyrophosphatase activity (ortholog); INVOLVED IN cementum mineralization; dephosphorylation; response to glucocorticoid; PARTICIPATES IN hypophosphatasia disease pathway; vitamin B6 metabolic pathway; folate metabolic pathway; ASSOCIATED WITH Hypercholesterolemia; Uremia; Arteriosclerosis (ortholog); FOUND IN extracellular space; plasma membrane; extracellular exosome (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 1-(5-isoquinolinesulfonyl)-2-methylpiperazine; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Akp2; alkaline phosphatase 2 liver; alkaline phosphatase 2, liver; alkaline phosphatase liver/bone/kidney isozyme; alkaline phosphatase, tissue-nonspecific; alkaline phosphatase, tissue-nonspecific isozyme; AP-TNAP; MGC93545; PHOA; tissue-nonspecific alkaline phosphatase; tissue-nonspecific ALP alkaline phosphatase; TNSALP
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05156,086,496 - 156,141,513 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.05159,841,916 - 159,897,391 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.45156,501,739 - 156,558,727 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15156,511,778 - 156,568,766 (-)NCBI
Celera5148,347,371 - 148,402,292 (-)NCBI
Cytogenetic Map5q36NCBImapview
RH 3.4 Map51009.6RGD
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Alpl
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 2100
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-05-31
Status: ACTIVE