1,2-dimethylhydrazine increases expression ISO Shank3 (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in increased expression of SHANK3 mRNA CTD PMID:22206623 17beta-estradiol multiple interactions ISO SHANK3 (Homo sapiens) 6480464 [Estradiol co-treated with TGFB1 protein] results in increased expression of SHANK3 mRNA CTD PMID:30165855 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of SHANK3 mRNA CTD PMID:32145629 17beta-estradiol multiple interactions EXP 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of SHANK3 mRNA CTD PMID:32741896 17beta-estradiol 3-benzoate multiple interactions EXP 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of SHANK3 mRNA CTD PMID:32741896 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of SHANK3 mRNA CTD PMID:34747641 2,5-hexanedione multiple interactions EXP 6480464 [carbendazim co-treated with 2 and 5-hexanedione] affects the expression of SHANK3 mRNA CTD PMID:22382377 2,6-dinitrotoluene affects expression EXP 6480464 2 and 6-dinitrotoluene affects the expression of SHANK3 mRNA CTD PMID:21346803 4,4'-sulfonyldiphenol increases expression ISO Shank3 (Mus musculus) 6480464 bisphenol S results in increased expression of SHANK3 mRNA CTD PMID:30951980 4,4'-sulfonyldiphenol multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of SHANK3 mRNA CTD PMID:36041667 4,4'-sulfonyldiphenol affects methylation ISO Shank3 (Mus musculus) 6480464 bisphenol S affects the methylation of SHANK3 exon more ... CTD PMID:31683443 and PMID:33297965 4-hydroxyphenyl retinamide increases expression ISO Shank3 (Mus musculus) 6480464 Fenretinide results in increased expression of SHANK3 mRNA CTD PMID:28973697 5-aza-2'-deoxycytidine increases expression ISO SHANK3 (Homo sapiens) 6480464 Decitabine results in increased expression of SHANK3 mRNA CTD PMID:17419801 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of SHANK3 mRNA CTD PMID:24780913 aflatoxin B1 decreases expression ISO SHANK3 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased expression of SHANK3 mRNA CTD PMID:27153756 aflatoxin B1 increases methylation ISO SHANK3 (Homo sapiens) 6480464 Aflatoxin B1 results in increased methylation of SHANK3 intron CTD PMID:30157460 Aflatoxin B2 alpha increases methylation ISO SHANK3 (Homo sapiens) 6480464 aflatoxin B2 results in increased methylation of SHANK3 intron CTD PMID:30157460 antirheumatic drug increases expression ISO SHANK3 (Homo sapiens) 6480464 Antirheumatic Agents results in increased expression of SHANK3 mRNA CTD PMID:24449571 arsane affects methylation ISO SHANK3 (Homo sapiens) 6480464 Arsenic affects the methylation of SHANK3 gene CTD PMID:25304211 arsenic atom affects methylation ISO SHANK3 (Homo sapiens) 6480464 Arsenic affects the methylation of SHANK3 gene CTD PMID:25304211 benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of SHANK3 mRNA CTD PMID:21839799 benzo[a]pyrene affects methylation ISO SHANK3 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of SHANK3 promoter CTD PMID:27901495 benzo[e]pyrene increases methylation ISO SHANK3 (Homo sapiens) 6480464 benzo(e)pyrene results in increased methylation of SHANK3 intron CTD PMID:30157460 bis(2-ethylhexyl) phthalate multiple interactions EXP 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of SHANK3 promoter CTD PMID:23359474 bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of SHANK3 mRNA more ... CTD PMID:23359474 more ... bisphenol A decreases methylation ISO SHANK3 (Homo sapiens) 6480464 bisphenol A results in decreased methylation of SHANK3 gene CTD PMID:31601247 bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of SHANK3 gene CTD PMID:28505145 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of SHANK3 mRNA CTD PMID:25181051 more ... bisphenol F increases expression ISO Shank3 (Mus musculus) 6480464 bisphenol F results in increased expression of SHANK3 mRNA CTD PMID:30951980 bisphenol F multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of SHANK3 mRNA CTD PMID:36041667 bisphenol F multiple interactions ISO SHANK3 (Homo sapiens) 6480464 [bisphenol F co-treated with Fulvestrant] results in increased methylation of SHANK3 gene CTD PMID:31601247 Butylparaben multiple interactions EXP 6480464 [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of SHANK3 mRNA CTD PMID:25607892 C60 fullerene increases expression EXP 6480464 fullerene C60 results in increased expression of SHANK3 mRNA CTD PMID:19167457 cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of SHANK3 mRNA CTD PMID:33453195 carbendazim multiple interactions EXP 6480464 [carbendazim co-treated with 2 and 5-hexanedione] affects the expression of SHANK3 mRNA CTD PMID:22382377 chloroacetaldehyde affects expression ISO SHANK3 (Homo sapiens) 6480464 chloroacetaldehyde affects the expression of SHANK3 mRNA CTD PMID:25596134 chlorpyrifos increases expression ISO Shank3 (Mus musculus) 6480464 Chlorpyrifos results in increased expression of SHANK3 mRNA CTD PMID:37019170 cidofovir anhydrous affects expression ISO SHANK3 (Homo sapiens) 6480464 Cidofovir affects the expression of SHANK3 mRNA CTD PMID:25596134 clodronic acid decreases expression ISO SHANK3 (Homo sapiens) 6480464 Clodronic Acid results in decreased expression of SHANK3 mRNA CTD PMID:25596134 cobalt dichloride decreases expression EXP 6480464 cobaltous chloride results in decreased expression of SHANK3 mRNA CTD PMID:24386269 cocaine multiple interactions ISO Shank3 (Mus musculus) 6480464 [Cocaine co-treated with FOS protein mutant form] results in decreased expression of SHANK3 mRNA CTD PMID:18355967 copper atom multiple interactions EXP 6480464 Copper inhibits the reaction [Potassium results in increased expression of SHANK3 protein] and Copper inhibits the reaction [zinc chloride results in increased expression of SHANK3 protein] CTD PMID:25007851 copper atom decreases expression ISO Shank3 (Mus musculus) 6480464 Copper results in decreased expression of SHANK3 protein CTD PMID:25007851 copper(0) multiple interactions EXP 6480464 Copper inhibits the reaction [Potassium results in increased expression of SHANK3 protein] and Copper inhibits the reaction [zinc chloride results in increased expression of SHANK3 protein] CTD PMID:25007851 copper(0) decreases expression ISO Shank3 (Mus musculus) 6480464 Copper results in decreased expression of SHANK3 protein CTD PMID:25007851 copper(II) chloride multiple interactions EXP 6480464 [COMMD1 protein co-treated with zinc chloride co-treated with cupric chloride] results in increased expression of SHANK3 protein CTD PMID:25007851 crocidolite asbestos increases expression ISO Shank3 (Mus musculus) 6480464 Asbestos and Crocidolite results in increased expression of SHANK3 mRNA CTD PMID:29279043 crocidolite asbestos decreases methylation ISO SHANK3 (Homo sapiens) 6480464 Asbestos and Crocidolite results in decreased methylation of SHANK3 3' UTR CTD PMID:29523930 cyclosporin A decreases expression ISO SHANK3 (Homo sapiens) 6480464 Cyclosporine results in decreased expression of SHANK3 mRNA CTD PMID:25562108 dibutyl phthalate multiple interactions EXP 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of SHANK3 promoter CTD PMID:23359474 dicrotophos increases expression ISO SHANK3 (Homo sapiens) 6480464 dicrotophos results in increased expression of SHANK3 mRNA CTD PMID:28302478 dioxygen increases expression ISO SHANK3 (Homo sapiens) 6480464 Oxygen deficiency results in increased expression of SHANK3 mRNA CTD PMID:25596134 dorsomorphin multiple interactions ISO SHANK3 (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxorubicin affects methylation EXP 6480464 Doxorubicin affects the methylation of SHANK3 gene CTD PMID:28962528 doxorubicin decreases expression ISO SHANK3 (Homo sapiens) 6480464 Doxorubicin results in decreased expression of SHANK3 mRNA CTD PMID:29803840 enzacamene multiple interactions EXP 6480464 [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of SHANK3 mRNA CTD PMID:25607892 ethanol decreases expression ISO Shank3 (Mus musculus) 6480464 Ethanol results in decreased expression of SHANK3 mRNA CTD PMID:29018328 ethanol increases expression ISO Shank3 (Mus musculus) 6480464 Ethanol results in increased expression of SHANK3 mRNA CTD PMID:30319688 ethanol affects splicing ISO Shank3 (Mus musculus) 6480464 Ethanol affects the splicing of SHANK3 mRNA CTD PMID:30319688 fulvestrant multiple interactions ISO SHANK3 (Homo sapiens) 6480464 [bisphenol F co-treated with Fulvestrant] results in increased methylation of SHANK3 gene CTD PMID:31601247 furan decreases expression EXP 6480464 furan results in decreased expression of SHANK3 mRNA CTD PMID:25539665 and PMID:26194646 glyphosate increases methylation EXP 6480464 Glyphosate results in increased methylation of SHANK3 gene CTD PMID:31011160 L-methionine decreases expression EXP 6480464 Methionine results in decreased expression of SHANK3 mRNA and Methionine results in decreased expression of SHANK3 protein CTD PMID:17419801 lipopolysaccharide multiple interactions EXP 6480464 [Lipopolysaccharides co-treated with Ranitidine] results in decreased expression of SHANK3 mRNA CTD PMID:16415329 methapyrilene increases methylation ISO SHANK3 (Homo sapiens) 6480464 Methapyrilene results in increased methylation of SHANK3 intron CTD PMID:30157460 methoxychlor increases methylation EXP 6480464 Methoxychlor results in increased methylation of SHANK3 gene CTD PMID:23303685 methoxychlor affects methylation EXP 6480464 Methoxychlor affects the methylation of SHANK3 gene CTD PMID:35440735 Methylazoxymethanol acetate decreases expression EXP 6480464 Methylazoxymethanol Acetate results in decreased expression of SHANK3 mRNA CTD PMID:28349193 N-methyl-4-phenylpyridinium increases expression ISO SHANK3 (Homo sapiens) 6480464 1-Methyl-4-phenylpyridinium results in increased expression of SHANK3 mRNA CTD PMID:24810058 N-methyl-D-aspartic acid multiple interactions ISO Shank3 (Mus musculus) 6480464 N-Methylaspartate inhibits the reaction [gelsenicine results in increased phosphorylation of SHANK3 protein] CTD PMID:34389372 N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine multiple interactions EXP 6480464 [Lipopolysaccharides co-treated with Ranitidine] results in decreased expression of SHANK3 mRNA CTD PMID:16415329 niclosamide increases expression ISO SHANK3 (Homo sapiens) 6480464 Niclosamide results in increased expression of SHANK3 mRNA CTD PMID:36318118 orphenadrine affects expression EXP 6480464 Orphenadrine affects the expression of SHANK3 mRNA CTD PMID:23665939 ozone multiple interactions ISO Shank3 (Mus musculus) 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of SHANK3 mRNA CTD PMID:34911549 phenanthrene decreases expression ISO Shank3 (Mus musculus) 6480464 phenanthrene results in decreased expression of SHANK3 mRNA CTD PMID:34453960 phenanthrene multiple interactions ISO Shank3 (Mus musculus) 6480464 Sirolimus inhibits the reaction [phenanthrene results in decreased expression of SHANK3 mRNA] CTD PMID:34453960 phenylmercury acetate decreases expression ISO SHANK3 (Homo sapiens) 6480464 Phenylmercuric Acetate results in decreased expression of SHANK3 mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO SHANK3 (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SHANK3 mRNA CTD PMID:27188386 phosgene affects expression ISO Shank3 (Mus musculus) 6480464 Phosgene affects the expression of SHANK3 mRNA CTD PMID:16300373 potassium atom multiple interactions EXP 6480464 Copper inhibits the reaction [Potassium results in increased expression of SHANK3 protein] CTD PMID:25007851 potassium atom increases expression EXP 6480464 Potassium results in increased expression of SHANK3 protein CTD PMID:25007851 potassium dichromate decreases expression ISO Shank3 (Mus musculus) 6480464 Potassium Dichromate results in decreased expression of SHANK3 mRNA CTD PMID:23608068 ranitidine multiple interactions EXP 6480464 [Lipopolysaccharides co-treated with Ranitidine] results in decreased expression of SHANK3 mRNA CTD PMID:16415329 resveratrol multiple interactions ISO SHANK3 (Homo sapiens) 6480464 [Plant Extracts co-treated with Resveratrol] results in decreased expression of SHANK3 mRNA CTD PMID:23557933 S-butyl-DL-homocysteine (S,R)-sulfoximine decreases expression ISO Shank3 (Mus musculus) 6480464 Buthionine Sulfoximine results in decreased expression of SHANK3 mRNA CTD PMID:15878706 SB 431542 multiple interactions ISO SHANK3 (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 serpentine asbestos increases methylation ISO SHANK3 (Homo sapiens) 6480464 Asbestos and Serpentine results in increased methylation of SHANK3 5' UTR CTD PMID:29523930 sirolimus multiple interactions ISO Shank3 (Mus musculus) 6480464 Sirolimus inhibits the reaction [phenanthrene results in decreased expression of SHANK3 mRNA] CTD PMID:34453960 temozolomide increases expression ISO SHANK3 (Homo sapiens) 6480464 Temozolomide results in increased expression of SHANK3 mRNA CTD PMID:31758290 testosterone multiple interactions EXP 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of SHANK3 mRNA CTD PMID:32741896 triptonide increases expression ISO Shank3 (Mus musculus) 6480464 triptonide results in increased expression of SHANK3 mRNA CTD PMID:33045310 valproic acid affects expression ISO SHANK3 (Homo sapiens) 6480464 Valproic Acid affects the expression of SHANK3 mRNA CTD PMID:25979313 valproic acid affects splicing EXP 6480464 Valproic Acid affects the splicing of SHANK3 mRNA CTD PMID:29427782 valproic acid multiple interactions ISO SHANK3 (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SHANK3 mRNA CTD PMID:27188386 valproic acid decreases expression ISO SHANK3 (Homo sapiens) 6480464 Valproic Acid results in decreased expression of SHANK3 mRNA CTD PMID:23179753 and PMID:26272509 vorinostat decreases expression ISO SHANK3 (Homo sapiens) 6480464 vorinostat results in decreased expression of SHANK3 mRNA CTD PMID:27188386 zinc atom affects binding EXP 6480464 Zinc binds to SHANK3 protein CTD PMID:16793273 zinc atom affects folding EXP 6480464 Zinc affects the folding of SHANK3 protein CTD PMID:16793273 zinc dichloride increases expression EXP 6480464 zinc chloride results in increased expression of SHANK3 protein CTD PMID:25007851 zinc dichloride multiple interactions EXP 6480464 [COMMD1 protein co-treated with zinc chloride co-treated with cupric chloride] results in increased expression of SHANK3 protein and Copper inhibits the reaction [zinc chloride results in increased expression of SHANK3 protein] CTD PMID:25007851 zinc(0) affects binding EXP 6480464 Zinc binds to SHANK3 protein CTD PMID:16793273 zinc(0) affects folding EXP 6480464 Zinc affects the folding of SHANK3 protein CTD PMID:16793273