Gene: Npr1 (natriuretic peptide receptor 1) Rattus norvegicus
Symbol: Npr1
Name: natriuretic peptide receptor 1
Description: ENCODES a protein that exhibits GTP binding; guanylate cyclase activity; natriuretic peptide receptor activity; INVOLVED IN cell surface receptor signaling pathway; cGMP biosynthetic process; dopamine metabolic process; PARTICIPATES IN atrial natriuretic peptide signaling pathway; brain natriuretic peptide signaling pathway; purine metabolic pathway; ASSOCIATED WITH increased systemic arterial blood pressure; increased systemic arterial diastolic blood pressure; ASSOCIATED WITH Hypertension; Hypertrophy, Left Ventricular; Aortic Rupture (ortholog); FOUND IN plasma membrane; receptor complex (ortholog); INTERACTS WITH 2,6-dinitrotoluene; 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine; 3,3',4,4',5-pentachlorobiphenyl
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: ANP-A; ANPR-A; Anpra; atrial natriuretic peptide A-type receptor; atrial natriuretic peptide receptor 1; atrial natriuretic peptide receptor A; atrial natriuretic peptide receptor type A; GC-A; Gca; guanylate cyclase A; Natriuretic peptide receptor A/Guanylate cyclase A; natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A); NPR-A; Npra
Orthologs:
Is Marker For: Strains:   SS.MNS-(Mme-Gca)/Ayd  
QTLs:   Niddm8   Bp19   Cm67   Bp363  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02189,840,403 - 189,857,032 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.02209,271,276 - 209,287,892 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.42182,724,916 - 182,740,242 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12182,675,021 - 182,690,348 (-)NCBI
Celera2169,869,831 - 169,885,101 (-)NCBI
Cytogenetic Map2q34NCBImapview
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Npr1
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 3195
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-08-09
Status: ACTIVE