Smad3 (SMAD family member 3) - Rat Genome Database

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Keyword

Gene: Smad3 (SMAD family member 3) Rattus norvegicus

Symbol:

Smad3

Name:

SMAD family member 3

Description:

ENCODES a protein that exhibits DNA binding; enzyme binding; sequence-specific DNA binding; INVOLVED IN activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway; negative regulation of apoptotic process; negative regulation of cell proliferation; PARTICIPATES IN transforming growth factor-beta Smad dependent signaling pathway; altered transforming growth factor-beta Smad dependent signaling pathway; colorectal cancer pathway; ASSOCIATED WITH liver fibrosis; ASSOCIATED WITH Colorectal Neoplasms (ortholog); Colorectal Neoplasms, Hereditary Nonpolyposis (ortholog); Endometrial Neoplasms (ortholog); FOUND IN cytoplasm; nucleus; protein complex; INTERACTS WITH 2-acetamidofluorene; benazepril; benzo[a]pyrene

Type:

protein-coding

RefSeq Status:

VALIDATED

Also known as:

MAD (mothers against decapentaplegic Drosophila) homolog 3; MAD (mothers against decapentaplegic, Drosophila) homolog 3; MAD homolog 3; MAD homolog 3 (Drosophila); mad3; mad3; Madh3; mothers against decapentaplegic homolog 3; mothers against DPP homolog 3; SMAD 3; Smad 3; SMAD family member 3

Orthologs:

Homo sapiens : SMAD3 (SMAD family member 3) HGNC
Mus musculus : Smad3 (SMAD family member 3) MGI

Latest Assembly:

RGSC Genome Assembly v3.4

Position:

Map	Chr	Position	Strand	Source
Rat Cytogenetic Map	8	q24		NCBI
RGSC Genome Assembly v5.0	8	68,274,132 - 68,397,727	-	NCBI
RGSC Genome Assembly v3.4	8	67,803,909 - 67,952,056	-	NCBI
Rat Celera Assembly	8	63,520,702 - 63,647,062	-	NCBI
Genome Assembly 3.1	8	67,822,964 - 67,971,110	-	NCBI