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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3032
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Smad3
Name: SMAD family member 3
Acc ID: CHEBI:34440
Term: 4-nonylphenol
Definition: A member of the class of phenols that is phenol which is para-substituted with a nonyl group.
Chemical ID: MESH:C041594
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Smad3decreases phosphorylationISOSMAD3 (Homo sapiens)6480464CTD4-nonylphenol results in decreased phosphorylation of SMAD3 proteinPMID:24308608
Smad3multiple interactionsISOSMAD3 (Homo sapiens)6480464CTDfulvestrant inhibits the reaction [4-nonylphenol results in decreased phosphorylation of SMAD3 protein]PMID:24308608
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