GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Smad3 | multiple interactions | ISO | Smad3 (Mus musculus) | 6480464 | CTD | Zinc inhibits the reaction [arsenite inhibits the reaction [TGFB2 protein affects the localization of SMAD3 protein]]; Zinc inhibits the reaction [monomethylarsonous acid inhibits the reaction [TGFB2 protein affects the localization of SMAD3 protein]]; Zinc promotes the reaction [SMAD3 protein modified form binds to SMAD2 protein modified form binds to NFIC protein]; Zinc results in increased stability of and results in increased activity of SMAD3 protein | PMID:22228435 PMID:26354774 | |
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