GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Smad3 | affects phosphorylation | EXP | | 6480464 | CTD | Diethylnitrosamine affects the phosphorylation of SMAD3 protein | PMID:19418558 | Smad3 | multiple interactions | EXP | | 6480464 | CTD | [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased phosphorylation of SMAD3 protein; IFNA2 protein promotes the reaction [[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased phosphorylation of SMAD3 protein]; pyrazolanthrone inhibits the reaction [Diethylnitrosamine affects the phosphorylation of SMAD3 protein] | PMID:15368444 PMID:19418558 | Smad3 | decreases expression | ISO | Smad3 (Mus musculus) | 6480464 | CTD | Diethylnitrosamine results in decreased expression of SMAD3 protein modified form | PMID:33290806 | Smad3 | increases phosphorylation | ISO | Smad3 (Mus musculus) | 6480464 | CTD | Diethylnitrosamine results in increased phosphorylation of SMAD3 protein | PMID:33290806 | Smad3 | multiple interactions | ISO | Smad3 (Mus musculus) | 6480464 | CTD | salvianolic acid B affects the reaction [Diethylnitrosamine results in decreased expression of SMAD3 protein modified form]; salvianolic acid B affects the reaction [SMAD3 protein modified form affects the reaction [Diethylnitrosamine affects the expression of SERPINE1 protein]]; salvianolic acid B affects the reaction [SMAD3 protein modified form affects the reaction [Diethylnitrosamine results in increased expression of ACTA2 protein]]; salvianolic acid B affects the reaction [SMAD3 protein modified form affects the reaction [Diethylnitrosamine results in increased expression of GPT protein]]; salvianolic acid B affects the reaction [SMAD3 protein modified form affects the reaction [Diethylnitrosamine results in increased expression of GSTP1 protein]]; salvianolic acid B affects the reaction [SMAD3 protein mutant form affects the reaction [Diethylnitrosamine affects the expression of SERPINE1 protein]]; salvianolic acid B inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of SMAD3 protein]; salvianolic acid B inhibits the reaction [SMAD3 protein modified form affects the reaction [Diethylnitrosamine results in decreased expression of CDKN1A protein]]; salvianolic acid B inhibits the reaction [SMAD3 protein modified form affects the reaction [Diethylnitrosamine results in decreased expression of SMAD3 protein modified form]]; salvianolic acid B inhibits the reaction [SMAD3 protein modified form affects the reaction [Diethylnitrosamine results in increased phosphorylation of SMAD3 protein]]; salvianolic acid B inhibits the reaction [SMAD3 protein mutant form affects the reaction [Diethylnitrosamine results in increased expression of MYC protein]]; SMAD3 protein modified form affects the reaction [Diethylnitrosamine affects the expression of SERPINE1 protein]; SMAD3 protein modified form affects the reaction [Diethylnitrosamine results in decreased expression of CDKN1A protein]; SMAD3 protein modified form affects the reaction [Diethylnitrosamine results in decreased expression of SMAD3 protein modified form]; SMAD3 protein modified form affects the reaction [Diethylnitrosamine results in increased expression of ACTA2 protein]; SMAD3 protein modified form affects the reaction [Diethylnitrosamine results in increased expression of GPT protein]; SMAD3 protein modified form affects the reaction [Diethylnitrosamine results in increased expression of GSTP1 protein]; SMAD3 protein modified form affects the reaction [Diethylnitrosamine results in increased expression of MYC protein]; SMAD3 protein modified form affects the reaction [Diethylnitrosamine results in increased phosphorylation of SMAD3 protein]; SMAD3 protein modified form affects the reaction [salvianolic acid B inhibits the reaction [Diethylnitrosamine results in increased expression of MYC protein]] | PMID:33290806 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |