Lonrf1 (LON peptidase N-terminal domain and ring finger 1)

Gene: Lonrf1 (LON peptidase N-terminal domain and ring finger 1) Rattus norvegicus

Analyze

Symbol:

Lonrf1

Name:

LON peptidase N-terminal domain and ring finger 1

RGD ID:

1562583

Description:

Predicted to enable metal ion binding activity. Predicted to be located in cytoplasm. Orthologous to human LONRF1 (LON peptidase N-terminal domain and ring finger 1); INTERACTS WITH (+)-schisandrin B; bisphenol A; indole-3-methanol.

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

LOC306505; LON peptidase N-terminal domain and RING finger protein 1; RGD1562583; similar to hypothetical protein FLJ23749

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	62,687,931 - 62,718,525 (+)	NCBI		GRCr8
mRatBN7.2	16	55,984,572 - 56,015,156 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	55,984,463 - 56,015,156 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	16	59,564,548 - 59,594,252 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	59,564,419 - 59,593,852 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	59,243,387 - 59,272,649 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	59,651,010 - 59,703,999 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	16	54,041,326 - 54,070,974 (+)	NCBI		Celera
Cytogenetic Map	16	q12.2	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1,2-dimethylhydrazine (ISO)

17beta-hydroxy-5alpha-androstan-3-one (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

4-hydroxyphenyl retinamide (ISO)

aflatoxin B1 (ISO)

aristolochic acid A (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP,ISO)

butanal (ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

cisplatin (ISO)

clothianidin (ISO)

cyclosporin A (ISO)

diallyl trisulfide (ISO)

epoxiconazole (ISO)

ethyl methanesulfonate (ISO)

fluoxetine (ISO)

formaldehyde (ISO)

indole-3-methanol (EXP)

leflunomide (ISO)

methyl methanesulfonate (ISO)

methylmercury chloride (ISO)

nickel atom (ISO)

niclosamide (ISO)

phenobarbital (ISO)

propiconazole (ISO)

quercetin (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

testosterone (ISO)

tetrachloromethane (EXP,ISO)

thioacetamide (EXP)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

cytoplasm (IEA)

Molecular Function

metal ion binding (IEA)

protein binding (ISO)

ubiquitin protein ligase activity (IBA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:19028597

Genomics

Comparative Map Data

Lonrf1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	62,687,931 - 62,718,525 (+)	NCBI		GRCr8
mRatBN7.2	16	55,984,572 - 56,015,156 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	55,984,463 - 56,015,156 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	16	59,564,548 - 59,594,252 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	59,564,419 - 59,593,852 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	59,243,387 - 59,272,649 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	59,651,010 - 59,703,999 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	16	54,041,326 - 54,070,974 (+)	NCBI		Celera
Cytogenetic Map	16	q12.2	NCBI

LONRF1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	12,721,906 - 12,755,526 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	12,721,906 - 12,756,073 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	12,579,415 - 12,613,035 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	12,623,777 - 12,657,363 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	8	11,544,278 - 11,577,192 (-)	NCBI		Celera
Cytogenetic Map	8	p23.1	NCBI
HuRef	8	11,121,429 - 11,155,007 (-)	NCBI		HuRef
CHM1_1	8	12,780,588 - 12,814,186 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	8	12,988,035 - 13,021,657 (-)	NCBI		T2T-CHM13v2.0

Lonrf1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	36,683,216 - 36,716,513 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	36,683,218 - 36,716,670 (-)	Ensembl		GRCm39 Ensembl
GRCm38	8	36,216,062 - 36,249,359 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	36,216,064 - 36,249,516 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	37,279,118 - 37,312,570 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	37,684,581 - 37,718,033 (-)	NCBI		MGSCv36	mm8
MGSCv36	8	35,148,248 - 35,180,441 (-)	NCBI		MGSCv36	mm8
Celera	8	38,855,912 - 38,888,822 (-)	NCBI		Celera
Cytogenetic Map	8	A4	NCBI
cM Map	8	23.05	NCBI

Lonrf1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955463	4,282,609 - 4,318,716 (+)	NCBI	ChiLan1.0	ChiLan1.0

LONRF1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	31,160,396 - 31,194,004 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	6,866,784 - 6,900,412 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	11,919,627 - 11,953,249 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	8,674,290 - 8,695,676 (-)	NCBI	panpan1.1	PanPan1.1	panPan2

LONRF1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	16	36,220,324 - 36,256,896 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	16	36,221,156 - 36,256,897 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	16	36,684,042 - 36,721,030 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	16	38,258,011 - 38,294,928 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	16	38,258,503 - 38,295,021 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	16	36,357,057 - 36,393,887 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	16	36,920,129 - 36,956,908 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	16	37,039,956 - 37,076,956 (-)	NCBI		UU_Cfam_GSD_1.0

Lonrf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404943	42,940,974 - 42,972,894 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936573	2,170,724 - 2,202,429 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936573	2,169,534 - 2,201,456 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LONRF1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	17	883,322 - 917,161 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	17	883,980 - 917,221 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	17	712,524 - 754,880 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LONRF1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	10,804,302 - 10,837,813 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	10,805,478 - 10,837,720 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666052	31,553,786 - 31,587,324 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Lonrf1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624839	4,247,428 - 4,278,881 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Lonrf1
200 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	123
Count of miRNA genes:	99
Interacting mature miRNAs:	103
Transcripts:	ENSRNOT00000015142
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1600378	Arunc4	Aerobic running capacity QTL 4		0.03	exercise endurance trait (VT:0002332)	maximum distance run on treadmill (CMO:0001406)	16	380245	80345693	Rat
2312660	Bw95	Body weight QTL 95		0.05	inguinal fat pad mass (VT:0010424)	inguinal fat pad weight to body weight ratio (CMO:0001253)	16	832236	59492508	Rat
2312663	Slep9	Serum leptin concentration QTL 9		0.001	blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	16	832236	59492508	Rat
2312666	Insul16	Insulin level QTL 16		0.01	blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	16	832236	59492508	Rat
2312669	Stl23	Serum triglyceride level QTL 23		0.01	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	16	832236	59492508	Rat
737826	Alc11	Alcohol consumption QTL 11	3.2		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	16	4227609	60252231	Rat
70205	Gcr3	Gastric cancer resistance QTL 3	2.3		stomach morphology trait (VT:0000470)	stomach tumor depth of invasion (CMO:0001888)	16	17696791	82635055	Rat
70205	Gcr3	Gastric cancer resistance QTL 3	2.3		stomach morphology trait (VT:0000470)	stomach tumor depth of invasion (CMO:0001888)	16	17696791	82635055	Rat
70205	Gcr3	Gastric cancer resistance QTL 3	2.3		stomach morphology trait (VT:0000470)	stomach tumor diameter (CMO:0001889)	16	17696791	82635055	Rat
70205	Gcr3	Gastric cancer resistance QTL 3	2.3		stomach morphology trait (VT:0000470)	stomach tumor diameter (CMO:0001889)	16	17696791	82635055	Rat
70215	Niddm29	Non-insulin dependent diabetes mellitus QTL 29	3.54		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	16	19004435	75226532	Rat
2302057	Pia29	Pristane induced arthritis QTL 29	3.6	0.001	blood autoantibody amount (VT:0003725)	serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)	16	21735975	66735975	Rat
8694453	Bw172	Body weight QTL 172	8.33	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	16	24325513	69325513	Rat
6903294	Stl30	Serum triglyceride level QTL 30	2.6	0.0013	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	16	25152793	70152793	Rat
1298529	Arunc1	Aerobic running capacity QTL 1	4		exercise endurance trait (VT:0002332)	maximum distance run on treadmill (CMO:0001406)	16	31951520	60148445	Rat
1578768	Stresp22	Stress response QTL 22	2.8		thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	16	35288870	80288870	Rat
2293690	Bss45	Bone structure and strength QTL 45	5.13	0.0001	lumbar vertebra morphology trait (VT:0010494)	lumbar vertebra cortical cross-sectional area (CMO:0001690)	16	37752156	82752156	Rat
2300163	Bmd64	Bone mineral density QTL 64	5.3	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	16	37752156	82752156	Rat
7205510	Activ5	Activity QTL 5	3.78	0.00028	locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	16	42396345	84729064	Rat
8694429	Bw164	Body weight QTL 164	5	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	16	52726464	84729064	Rat
8694364	Abfw7	Abdominal fat weight QTL 7	12.22	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	16	52726464	84729064	Rat
7411648	Foco22	Food consumption QTL 22	15	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	16	52726464	84729064	Rat
631525	Pia14	Pristane induced arthritis QTL 14	4.4		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	16	55711087	83402471	Rat

Markers in Region

D16Got53

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	16	55,996,590 - 55,996,783 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	59,576,548 - 59,576,740	NCBI	Rnor6.0
Rnor_5.0	16	59,255,032 - 59,255,224	UniSTS	Rnor5.0
RGSC_v3.4	16	59,686,752 - 59,686,945	RGD	RGSC3.4
RGSC_v3.4	16	59,686,753 - 59,686,945	UniSTS	RGSC3.4
RGSC_v3.1	16	59,686,828 - 59,687,020	RGD
Celera	16	54,053,331 - 54,053,523	UniSTS
RH 3.4 Map	16	558.2	UniSTS
RH 3.4 Map	16	558.2	RGD
RH 2.0 Map	16	645.0	RGD
Cytogenetic Map	16	q12.2	UniSTS

BE113584

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	16	55,983,883 - 55,984,047 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	59,563,840 - 59,564,003	NCBI	Rnor6.0
Rnor_5.0	16	59,242,695 - 59,242,858	UniSTS	Rnor5.0
RGSC_v3.4	16	59,673,929 - 59,674,092	UniSTS	RGSC3.4
Celera	16	54,040,649 - 54,040,812	UniSTS
RH 3.4 Map	16	559.6	UniSTS
Cytogenetic Map	16	q12.2	UniSTS

BE116164

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	16	56,003,629 - 56,003,814 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	59,583,648 - 59,583,832	NCBI	Rnor6.0
Rnor_5.0	16	59,262,132 - 59,262,316	UniSTS	Rnor5.0
RGSC_v3.4	16	59,693,792 - 59,693,976	UniSTS	RGSC3.4
Celera	16	54,060,370 - 54,060,554	UniSTS
RH 3.4 Map	16	560.21	UniSTS
Cytogenetic Map	16	q12.2	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium		4	7	6	2	6			52	4	22	6
Low	3	39	50	35	17	35	8	11	22	31	19	5	8
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008773508	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017600372	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063275867	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473970	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000016	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000083434 ⟹ ENSRNOP00000072463

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	16	55,984,463 - 56,015,156 (+)	Ensembl
Rnor_6.0 Ensembl	16	59,564,419 - 59,593,852 (+)	Ensembl

RefSeq Acc Id:

XM_017600372 ⟹ XP_017455861

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	16	62,687,935 - 62,718,525 (+)	NCBI
mRatBN7.2	16	55,984,572 - 56,015,156 (+)	NCBI
Rnor_6.0	16	59,564,548 - 59,594,252 (+)	NCBI

Sequence:

show sequence

CCCCCCTGCTCGCCGGCCGCGTGCGGAGCCGCGCGCCCCGGAGGTTCCCGGACCGTGGCGGCGG
GCGGCGACGGAGGAGCAGCCCTGCGCGGGCCATGTCTTCTCCGGCCGTGGCGAGGGCGTCCCCG
GGCGGGAATCGGGAGACGGCCGGCGGACCGCGGAGCCGGAACGGGCCGTGGGAAGTGGGCGGCG
GCGAGCGGTTGGAGCGCGCGGGCGCGGAGCCGGGGCGCTGGGAGCTTCTGCTCCGCCGCGGCGA
GCTGCTGGCGCTGGGCGGCCACCTGAAGGGAGCGCTGGAGGCGTTCGCGGCTGCGCTGCGCCGC
GGGGCCCCGGCCAGGCCCGAGCGCCTCGGTTCGCTAGTGGACTGCCTGGTGTTCAGCTACCGGC
TCCGTCACGGGCTGCGCTGGAGCGCGGCACCCGCCGCGGGCGCGGCCGGGCTGCTCAGCTGCCT
GGGCTGCCGGGGCTTCCTAAGTGAGCCGGTGACCGTGCCGTGCGGCCACAGCTACTGTCGCCGT
TGCCTACGGAGGGAACTGCGCGCCCGCTGCCGCCTGTGCCGGGACCGTCTGCCACCCGCCGCCG
CCGCCTCCGAGGACCCCGCGNGCCCGGCGCCCCTGGCCGCCGCCATCGCCGACTCCGAAAAACC
GGTCGTGCTCAACCACCTGGCGGAGAAGNTGTTCCCGGGCCAGCGCGAGCGCGCGCGGGCGGCC
GGCCGCCTCGGGGAGCTACTACACGAAGGACGCTACCGGGAGGCCCTGGCCGCCGCCTGCGACG
CTCTGCGAGCAGAGCCGAGTGACCTGACTCTCAAAATCTACAGAGCGGAGTCCTACGCCGGCCT
GCAGGAGTTTAAAGCAGCCTTAGAGGATCTAAATGCAGTTCTCTTTCAGCTTCCCAACTGGCCC
GAGGTCTACTTCAGGAAAGGGAAAGTCCTGCAGGACGCCGGGTTCCTGGGCGACGCCTTACAGC
TCTTCCTTCAGTGCTTGGCCCTTGATGAAGACTTCGCACCTGCAAAGCTGCAAGTAGAAAAGAT
TCTGTGTGACTTACTGTCACCTGAAAACGTAAAGGAAGGCCTGAAGGGGTCTTCCTGGAGTTCG
TTACCGTGTACTAAAAGCAAACCTCTTGGTTTTCCGTCAGTAATGGAACAGCCACACTCCCCTC
CTGAGCTTGGCCTGAAGCAGACTGAAGAACAAGCGGAGGATGCCTCAGAGCCTGTCAAGGGAAG
CCTAAACCGCGCTCAGTCCGCACAAGCCATCAGTGCAGCAGCAGTGCCTGCCAGGGAGGATGGC
TTAAAGCGCGTGTGCTCGGAACCCGTACTGTGCGCTCAGGGAAAAGGCGCTCTGCTGAAAAGGA
AGCTGTCTCTCTTAGAACAGGATGTGATCATTAACGAGGACGGGAGGAATAAGCTCAAAAAGCA
AGAATCTCCCGGGGAAGACTGTATGTTCTCAATAGCTTATGGTGACATCCCGGAAGAACTAATA
GATGTCTCAGACTTCGAGTGTTCTCTCTGTATGAGGTTGTTTTTTGAGCCAGTAACAACCCCTT
GTGGACACTCATTCTGCAAGAATTGTCTTGAGCGTTGCTTAGATCATGCTCCATATTGTCCCCT
CTGCAAAGAAAGCTTAAAAGAGTACCTGGCAGACAGGAGGTACTGCGTCACGCAGCTATTGGAG
GACTTAATAGTGAAATACCTGCCGGATGAGCTGTCTGAGAGGAAGAAGATCTACGATGAGGAAA
CTGCCGAGCTCTCACACTTGACCAAGAATGTCCCAATATTCGTTTGCACTATGGCCTACCCCAC
TGTGCCTTGCCCTCTCCATGTGTTTGAGCCCAGATACAGGCTCATGATCCGAAGAAGTATCCAG
ACTGGAACCAAGCAGTTCGGGATGTGTGTCAGTGATACACAAAACAGTTTTGCAGATTATGGTT
GTATGTTACAAATTCGAAATGTGCATTTCTTACCTGACGGAAGGTCTGTTGTTGACACAGTTGG
AGGAAAGCGGTTCAGAGTTTTAAAAAGAGGAATGAAAGATGGGTATTGCACTGCGGACATTGAG
TATCTGGAAGATGTTAAGATTGAGAACGGAGATGAAATAAGGAGTCTGAGAGAACTCCACGACT
TGGTGTACTCGCAGGCCTGCAGCTGGTTTCAGAATTTAAGAGACAGATTTCGAAGCCAAATCCT
TCAACACTTTGGATCAATGCCAGAGAGGGAAGAAAACCTCCAGGCAACACCCAACGGACCTGCA
TGGTGTTGGTGGCTGCTGGCAGTCCTTCCTGTAGACCCGCGGTATCAGCTCTCTGTACTGTCAA
TGAAGTCTTTGGAGGAGCGGTTGACCAAGATACAGCATATTCTGACTTATTTTTCTAGAGACCA
ATCTAAGTAATGAACTGCTTGGATCTCGTTTTGCTCGCTCTTAGCCCAGAGGCTGAGAAGCGGT
TGGATCTTACTTTAAAGTCGCCCTGATCTGGCTCCTTGATGGCCGGATTGCCCGCTGCCTTTGC
ACACCCAGTGCTGGTTTGAGAAATTAAGGAAACTTTTCTTTTCTTCAACCTCCTGAATCTCGTG
GATCTGCAAATGAATACCTTCAACTAGGTCCTAGACCACTAAGAACTTGCACAGAAAACACGCA
CTGAATGTGTGTTAAACCTCGACATTGTGATAAAGTTGCACTATGTACCATACTCTAAATGAAC
TAAGAACTCCGTGTATGTATGATGTGTGTGTGTGTGCGCGTGTGCTTATACACATGTGTACGTG
TGTGTGCTCATGCACGTGTGTAT

hide sequence

RefSeq Acc Id:

XM_063275867 ⟹ XP_063131937

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	16	62,687,931 - 62,718,525 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_017455861	(Get FASTA)	NCBI Sequence Viewer
	XP_063131937	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM09209	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000072463
	ENSRNOP00000072463.2

RefSeq Acc Id:	XP_017455861 ⟸ XM_017600372
- Peptide Label:	isoform X2
- UniProtKB:	A0A0G2K313 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSSPAVARASPGGNRETAGGPRSRNGPWEVGGGERLERAGAEPGRWELLLRRGELLALGGHLKG ALEAFAAALRRGAPARPERLGSLVDCLVFSYRLRHGLRWSAAPAAGAAGLLSCLGCRGFLSEPV TVPCGHSYCRRCLRRELRARCRLCRDRLPPAAAASEDPAXPAPLAAAIADSEKPVVLNHLAEKX FPGQRERARAAGRLGELLHEGRYREALAAACDALRAEPSDLTLKIYRAESYAGLQEFKAALEDL NAVLFQLPNWPEVYFRKGKVLQDAGFLGDALQLFLQCLALDEDFAPAKLQVEKILCDLLSPENV KEGLKGSSWSSLPCTKSKPLGFPSVMEQPHSPPELGLKQTEEQAEDASEPVKGSLNRAQSAQAI SAAAVPAREDGLKRVCSEPVLCAQGKGALLKRKLSLLEQDVIINEDGRNKLKKQESPGEDCMFS IAYGDIPEELIDVSDFECSLCMRLFFEPVTTPCGHSFCKNCLERCLDHAPYCPLCKESLKEYLA DRRYCVTQLLEDLIVKYLPDELSERKKIYDEETAELSHLTKNVPIFVCTMAYPTVPCPLHVFEP RYRLMIRRSIQTGTKQFGMCVSDTQNSFADYGCMLQIRNVHFLPDGRSVVDTVGGKRFRVLKRG MKDGYCTADIEYLEDVKIENGDEIRSLRELHDLVYSQACSWFQNLRDRFRSQILQHFGSMPERE ENLQATPNGPAWCWWLLAVLPVDPRYQLSVLSMKSLEERLTKIQHILTYFSRDQSK hide sequence

RefSeq Acc Id:

ENSRNOP00000072463 ⟸ ENSRNOT00000083434

RefSeq Acc Id:	XP_063131937 ⟸ XM_063275867
- Peptide Label:	isoform X1

Protein Domains

Lon N-terminal RING-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A0A0G2K313-F1-model_v2	AlphaFold	A0A0G2K313	1-833	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1562583	AgrOrtholog
BioCyc Gene	G2FUF-11191	BioCyc
Ensembl Genes	ENSRNOG00000053706	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000083434.2	UniProtKB/TrEMBL
Gene3D-CATH	1.25.40.10	UniProtKB/TrEMBL
	2.30.130.40	UniProtKB/TrEMBL
	3.30.40.10	UniProtKB/TrEMBL
InterPro	Lon_prtase_N_sf	UniProtKB/TrEMBL
	Pept_S16_N	UniProtKB/TrEMBL
	PUA-like	UniProtKB/TrEMBL
	TPR-like_helical	UniProtKB/TrEMBL
	TPR_repeat	UniProtKB/TrEMBL
	Znf_C3HC4_RING-type	UniProtKB/TrEMBL
	Znf_RING	UniProtKB/TrEMBL
	Znf_RING/FYVE/PHD	UniProtKB/TrEMBL
	Znf_RING_CS	UniProtKB/TrEMBL
NCBI Gene	306505	ENTREZGENE
PANTHER	LON PEPTIDASE N-TERMINAL DOMAIN AND RING FINGER PROTEIN 1	UniProtKB/TrEMBL
	RING FINGER PROTEIN 127	UniProtKB/TrEMBL
Pfam	LON	UniProtKB/TrEMBL
	zf-C3HC4	UniProtKB/TrEMBL
	zf-C3HC4_2	UniProtKB/TrEMBL
PhenoGen	Lonrf1	PhenoGen
PROSITE	LON_N	UniProtKB/TrEMBL
	ZF_RING_1	UniProtKB/TrEMBL
	ZF_RING_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000053706	RatGTEx
SMART	LON	UniProtKB/TrEMBL
	RING	UniProtKB/TrEMBL
	TPR	UniProtKB/TrEMBL
Superfamily-SCOP	PUA-like	UniProtKB/TrEMBL
	RING/U-box	UniProtKB/TrEMBL
	SSF48452	UniProtKB/TrEMBL
UniProt	A0A0G2K313	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-30	Lonrf1	LON peptidase N-terminal domain and ring finger 1	Lonrf1_predicted	LON peptidase N-terminal domain and ring finger 1 (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-30	Lonrf1_predicted	LON peptidase N-terminal domain and ring finger 1 (predicted)	RGD1562583_predicted	similar to hypothetical protein FLJ23749 (predicted)	Symbol and Name updated	1299863	APPROVED
2006-03-07	RGD1562583_predicted	similar to hypothetical protein FLJ23749 (predicted)	LOC306505	similar to hypothetical protein FLJ23749	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC306505	similar to hypothetical protein FLJ23749			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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