RGD DISEASE ONTOLOGY - ANNOTATIONS
RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term: Memory Disorders
Accession: DOID:9008023
browse the term
Definition: Disturbances in registering an impression, in the retention of an acquired impression, or in the recall of an impression. Memory impairments are associated with DEMENTIA; CRANIOCEREBRAL TRAUMA; ENCEPHALITIS; ALCOHOLISM (see also ALCOHOL AMNESTIC DISORDER); SCHIZOPHRENIA; and other conditions.
Synonyms: exact_synonym: Age Related Memory Disorders; Age-Related Memory Disorder; Cognitive Retention Disorder; Cognitive Retention Disorders; Memory Deficit; Memory Deficits; Memory Disorder; Memory Loss; Memory Losses; Semantic Memory Disorder; Semantic Memory Disorders; Spatial Memory Disorder; Spatial Memory Disorders; memory impairment
related_synonym: MEMORY IMPAIRMENT, SUSCEPTIBILITY TO
primary_id: MESH:D008569
xref: EFO:0001072
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Abl1
ABL proto-oncogene 1, non-receptor tyrosine kinase
treatment
IMP ISO
RGD
PMID:18559370 PMID:18559370
RGD:8693418 , RGD:8693418
NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065
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Ace
angiotensin I converting enzyme
ISO IMP
GAD RGD
PMID:15118671 PMID:21864581
RGD:1331525 , RGD:6893483
NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
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Ache
acetylcholinesterase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:18599028
NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
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Adk
adenosine kinase
ISO
RGD
PMID:22521820
RGD:6482646
NCBI chr15:2,863,241...3,246,453
Ensembl chr15:2,863,244...3,246,510
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Adra1a
adrenoceptor alpha 1A
IDA
associated with brain injuries
RGD
PMID:20974230
RGD:5688366
NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500
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Agap2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
ISO
RGD
PMID:21632930
RGD:13838852
NCBI chr 7:62,897,282...62,914,295
Ensembl chr 7:62,897,282...62,914,295
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Akap5
A-kinase anchoring protein 5
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:18711127
NCBI chr 6:95,051,527...95,061,075
Ensembl chr 6:95,051,537...95,061,578
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Akt1
AKT serine/threonine kinase 1
treatment
ISO
RGD
PMID:29157831
RGD:401940181
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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Anapc2
anaphase promoting complex subunit 2
ISO
RGD
PMID:21191042
RGD:14696672
NCBI chr 3:8,086,434...8,098,182
Ensembl chr 3:8,086,462...8,098,178
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Apoc1
apolipoprotein C1
ISO
RGD
PMID:11714102
RGD:1578426
NCBI chr 1:79,347,057...79,350,340
Ensembl chr 1:79,346,136...79,350,375
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Apoe
apolipoprotein E
ISO
DNA:missense mutations, haplotypes:cds:p.C112R, p.R158C (human)
RGD
PMID:11714102 PMID:8584214
RGD:1578426 , RGD:12904706
NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
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App
amyloid beta precursor protein
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:15364477 PMID:18191838 PMID:18599028 PMID:19664757 PMID:19770021 PMID:20816828 PMID:22484447 PMID:23827522 PMID:24858312 PMID:25213453 PMID:25881725 PMID:26420483 PMID:26480858 PMID:27306655 PMID:27567873 PMID:28448946 PMID:29729307 PMID:35247505 More...
NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
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Avp
arginine vasopressin
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:11553362
NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425
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Bcl2
BCL2, apoptosis regulator
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17967740
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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Bdnf
brain-derived neurotrophic factor
treatment
ISO IEP
ClinVar Annotator: match by term: Memory impairment, susceptibility to associated with alcohol use disorder; protein:decreased expression:plasma (human) associated with alcohol use disorder;mRNA,protein:decreased expression:hippocampus associated with Subarachnoid Hemorrhage
ClinVar RGD
PMID:12140781 PMID:12161822 PMID:12553913 PMID:12836135 PMID:12888803 PMID:15115760 PMID:15337662 PMID:16152572 PMID:16172806 PMID:16222333 PMID:16344533 PMID:16389585 PMID:20075215 PMID:24033266 PMID:25741868 PMID:28492532 PMID:30277635 PMID:29157831 PMID:34427953 PMID:29704550 PMID:26822402 More...
RGD:401938665 , RGD:401940181 , RGD:401959600 , RGD:401960858 , RGD:401960859
NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
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Cacna1d
calcium voltage-gated channel subunit alpha1 D
IDA
RGD
PMID:12591156
RGD:704382
NCBI chr16:5,227,157...5,521,163
Ensembl chr16:5,228,306...5,668,215
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Caly
calcyon neuron-specific vesicular protein
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:30753204
NCBI chr 1:194,862,671...194,873,861
Ensembl chr 1:194,862,672...194,873,551
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Chd1
chromodomain helicase DNA binding protein 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:30728766
NCBI chr 1:56,661,743...56,729,119
Ensembl chr 1:56,664,054...56,728,125
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Chrm1
cholinergic receptor, muscarinic 1
ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:21682298 PMID:12483218
RGD:734777
NCBI chr 1:205,567,226...205,583,001
Ensembl chr 1:205,567,220...205,582,356
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Chrna7
cholinergic receptor nicotinic alpha 7 subunit
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:18848931
NCBI chr 1:116,711,559...116,837,269
Ensembl chr 1:116,714,711...116,837,240
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Cnr1
cannabinoid receptor 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:29294249
NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
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Comt
catechol-O-methyltransferase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:28195063
NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
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Cpe
carboxypeptidase E
ISO
RGD
PMID:18570185
RGD:6483325
NCBI chr16:25,030,276...25,142,231
Ensembl chr16:25,030,276...25,142,233
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Creb1
cAMP responsive element binding protein 1
treatment
IEP ISO IDA
protein:decreased expression:hippocampus associated with alcohol use disorder;mRNA:decreased expression:hippocampus associated with morphine dependence associated with Subarachnoid Hemorrhage
RGD
PMID:14670355 PMID:29157831 PMID:34427953 PMID:16598705 PMID:29704550 PMID:26822402 More...
RGD:10059396 , RGD:401940181 , RGD:401959600 , RGD:401959605 , RGD:401960858 , RGD:401960859
NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
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Cx3cr1
C-X3-C motif chemokine receptor 1
IMP
RGD
PMID:23855980
RGD:9491766
NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014
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Drd2
dopamine receptor D2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21592505
NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
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Egr1
early growth response 1
treatment
IEP
associated with Congenital Hypothyroidism
RGD
PMID:22192600
RGD:10395310
NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
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Gabra5
gamma-aminobutyric acid type A receptor subunit alpha 5
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20180861
NCBI chr 1:108,268,728...108,381,670
Ensembl chr 1:108,268,776...108,380,917
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Git1
GIT ArfGAP 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21499268
NCBI chr10:62,342,082...62,356,379
Ensembl chr10:62,342,299...62,356,373
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Grpr
gastrin releasing peptide receptor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17097693
NCBI chr X:30,998,425...31,038,442
Ensembl chr X:30,998,416...31,038,442
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Hdac2
histone deacetylase 2
treatment
ISO
RGD
PMID:22388814
RGD:9590324
NCBI chr20:40,548,244...40,571,609
Ensembl chr20:40,548,250...40,571,609
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Hif1a
hypoxia inducible factor 1 subunit alpha
treatment
ISO
RGD
PMID:22547371
RGD:10402407
NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
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Hrh3
histamine receptor H3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16488453
NCBI chr 3:167,191,551...167,196,642
Ensembl chr 3:167,191,558...167,196,642
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Htr1a
5-hydroxytryptamine receptor 1A
treatment
ISO IEP
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:12591222 PMID:25817367
RGD:405866362
NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442
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Htr2a
5-hydroxytryptamine receptor 2A
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:29294249
NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928
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Htr6
5-hydroxytryptamine receptor 6
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19733250
NCBI chr 5:151,295,269...151,312,853
Ensembl chr 5:151,296,662...151,311,912
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Htr7
5-hydroxytryptamine receptor 7
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21859099
NCBI chr 1:233,636,442...233,761,063
Ensembl chr 1:233,636,452...233,760,626
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Igf1
insulin-like growth factor 1
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:34632857
NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
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Igf2
insulin-like growth factor 2
treatment
IEP ISO
CTD Direct Evidence: therapeutic
CTD RGD
PMID:21270887 PMID:24012657
RGD:10402554
NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018
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Il1b
interleukin 1 beta
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21290410
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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Ins2
insulin 2
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:9264093
NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
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Kl
Klotho
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25309793 PMID:25550330
NCBI chr12:490,402...531,417
Ensembl chr12:490,399...530,080
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Lnpep
leucyl and cystinyl aminopeptidase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:11730987
NCBI chr 1:58,258,642...58,355,532
Ensembl chr 1:58,258,642...58,354,544
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Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25653350
NCBI chr 4:14,386,389...15,870,036
Ensembl chr 4:14,386,399...15,870,240
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Mapk1
mitogen activated protein kinase 1
treatment
ISO IDA
associated with Subarachnoid Hemorrhage
RGD
PMID:29157831 PMID:26822402
RGD:401940181 , RGD:401960859
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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Mapk3
mitogen activated protein kinase 3
treatment
ISO IDA
associated with Subarachnoid Hemorrhage
RGD
PMID:29157831 PMID:26822402
RGD:401940181 , RGD:401960859
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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Mapt
microtubule-associated protein tau
IDA ISO
CTD Direct Evidence: marker/mechanism ClinVar Annotator: match by term: Memory impairment
CTD ClinVar RGD
PMID:7783864 PMID:7936288 PMID:8940276 PMID:9088499 PMID:9392579 PMID:9641683 PMID:10202939 PMID:10329720 PMID:10443890 PMID:10446810 PMID:11255441 PMID:11402146 PMID:11641718 PMID:11708988 PMID:11912108 PMID:11971081 PMID:11971082 PMID:12368474 PMID:12847166 PMID:14755449 PMID:15372253 PMID:15950767 PMID:17923640 PMID:18525295 PMID:19365643 PMID:19766248 PMID:19786698 PMID:19884572 PMID:19914360 PMID:20045477 PMID:23680655 PMID:23885714 PMID:24556215 PMID:25683866 PMID:25741868 PMID:26136155 PMID:26467025 PMID:26528178 PMID:27594586 PMID:28097206 PMID:28492532 PMID:29203278 PMID:29860433 PMID:31810826 PMID:15524282 More...
RGD:1358432
NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
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Mdk
midkine
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:19217924
NCBI chr 3:77,901,134...77,903,997
Ensembl chr 3:77,901,158...77,903,130
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Mif
macrophage migration inhibitory factor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20177408
NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504 Ensembl chr 4:12,790,902...12,799,504
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Ncam1
neural cell adhesion molecule 1
treatment
IEP
associated with alcohol use disorder
RGD
PMID:16207289
RGD:401959613
NCBI chr 8:49,865,629...50,165,687
Ensembl chr 8:49,865,633...50,166,014
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Nos1
nitric oxide synthase 1
IMP
associated with Status Epilepticus
RGD
PMID:17549628
RGD:1642140
NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
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Npy
neuropeptide Y
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:2611661
NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495
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Nqo2
N-ribosyldihydronicotinamide:quinone dehydrogenase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20861374
NCBI chr17:30,909,482...30,938,725
Ensembl chr17:30,909,187...30,938,320
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Nr3c1
nuclear receptor subfamily 3, group C, member 1
treatment
IMP
RGD
PMID:23159706
RGD:408364992
NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
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Ntf4
neurotrophin 4
ISO
RGD
PMID:10869436
RGD:737722
NCBI chr 1:95,893,560...95,896,391
Ensembl chr 1:95,893,457...95,897,243
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Pnoc
prepronociceptin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:10401555
NCBI chr15:39,624,635...39,652,463
Ensembl chr15:39,624,641...39,651,867
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Prkn
parkin RBR E3 ubiquitin protein ligase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12915482
NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
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Prl
prolactin
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:36100143
NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
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Psen1
presenilin 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:25213453 PMID:27567873 PMID:28448946
NCBI chr 6:103,323,052...103,375,088
Ensembl chr 6:103,323,120...103,371,650
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Rel
REL proto-oncogene, NF-kB subunit
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20477932
NCBI chr14:97,690,105...97,721,194
Ensembl chr14:97,695,161...97,720,892
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RT1-Hb-ps1
RT1 class II, locus Hb, pseudogene 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:14975599
NCBI chr20:4,775,598...4,779,590
Ensembl chr20:4,774,650...4,780,618
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Sigmar1
sigma non-opioid intracellular receptor 1
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:15451042
NCBI chr 5:56,904,155...56,907,012
Ensembl chr 5:56,904,159...56,907,017
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Slc17a6
solute carrier family 17 member 6
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21295146
NCBI chr 1:101,212,489...101,252,543
Ensembl chr 1:101,212,489...101,252,542
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Slc17a7
solute carrier family 17 member 7
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21295146
NCBI chr 1:95,649,709...95,661,591
Ensembl chr 1:95,649,745...95,661,588
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Slc6a3
solute carrier family 6 member 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:17992686
NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
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Slc6a4
solute carrier family 6 member 4
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:18661256 PMID:18686203
NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384
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Sphk2
sphingosine kinase 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:24859201
NCBI chr 1:96,180,872...96,188,592
Ensembl chr 1:96,180,887...96,188,391
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Stat3
signal transducer and activator of transcription 3
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:17928813
NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
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Syp
synaptophysin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:21295146
NCBI chr X:14,849,444...14,864,553
Ensembl chr X:14,849,444...14,864,745
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Tyrobp
transmembrane immune signaling adaptor Tyrobp
ISO
ClinVar Annotator: match by term: Memory impairment
ClinVar
PMID:9536098 PMID:17576681 PMID:25741868 PMID:28492532 PMID:29930232
NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848
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Vegfa
vascular endothelial growth factor A
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:20801723
NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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App
amyloid beta precursor protein
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:12642396
NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
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Arc
activity-regulated cytoskeleton-associated protein
treatment
ISO
RGD
PMID:24012642
RGD:401938610
NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378
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Avp
arginine vasopressin
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:7562510
NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425
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Bche
butyrylcholinesterase
IMP
RGD
PMID:21771623
RGD:5688134
NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
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Bdnf
brain-derived neurotrophic factor
treatment
ISO IEP
protein:decreased expression:amygdala, hippocampus, prefrontal cortex
RGD
PMID:25061594 PMID:31400468 PMID:28716085
RGD:10059361 , RGD:401960871 , RGD:401960865
NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
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Cartpt
CART prepropeptide
treatment
IEP
associated with morphine withdrawal syndrome
RGD
PMID:32198124
RGD:407571681
NCBI chr 2:31,255,098...31,257,452
Ensembl chr 2:31,255,098...31,290,713
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Creb1
cAMP responsive element binding protein 1
treatment
ISO IDA
protein:decreased phosphorylation:amygdala, hippocampus, prefrontal cortex
RGD
PMID:28716085 PMID:31400468
RGD:401960865 , RGD:401960871
NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
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Csf2
colony stimulating factor 2
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:8877002
NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
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Drd3
dopamine receptor D3
IMP
RGD
PMID:15619116
RGD:7175071
NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596
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Gja1
gap junction protein, alpha 1
IMP
RGD
PMID:22665389
RGD:7207267
NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
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Gnai1
G protein subunit alpha i1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:11350863
NCBI chr 4:16,814,000...16,898,119
Ensembl chr 4:16,814,001...16,896,417
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Gnai3
G protein subunit alpha i3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:11350863
NCBI chr 2:195,742,765...195,780,720
Ensembl chr 2:195,742,642...195,780,742
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Grp
gastrin releasing peptide
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:11564462
NCBI chr18:59,388,679...59,402,061
Ensembl chr18:59,388,274...59,402,061
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Hrh3
histamine receptor H3
IDA ISO
CTD Direct Evidence: marker/mechanism
CTD RGD
PMID:11125734 PMID:17276409
RGD:1626421
NCBI chr 3:167,191,551...167,196,642
Ensembl chr 3:167,191,558...167,196,642
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Htr7
5-hydroxytryptamine receptor 7
IMP
RGD
PMID:18570192
RGD:6482184
NCBI chr 1:233,636,442...233,761,063
Ensembl chr 1:233,636,452...233,760,626
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Il1a
interleukin 1 alpha
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:8003924
NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
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Il2
interleukin 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:8241462
NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
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Il6
interleukin 6
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:9189931
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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Ngf
nerve growth factor
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:16405025 PMID:19694610
NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
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Pdyn
prodynorphin
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:7768285
NCBI chr 3:116,900,990...116,913,334
Ensembl chr 3:116,900,992...116,913,334
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Pomc
proopiomelanocortin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:2841920
NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
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Ppargc1a
PPARG coactivator 1 alpha
IEP
associated with morphine withdrawal syndrome;mRNA:increased expression:hippocamous (rat)
RGD
PMID:32198124
RGD:407571681
NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
G
Prep
prolyl endopeptidase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:8691432
NCBI chr20:48,556,211...48,653,165
Ensembl chr20:48,556,280...48,654,466
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Sigmar1
sigma non-opioid intracellular receptor 1
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:12028363
NCBI chr 5:56,904,155...56,907,012
Ensembl chr 5:56,904,159...56,907,017
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Tac1
tachykinin, precursor 1
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:7562510 PMID:9521815 PMID:20600432
NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178
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Trh
thyrotropin releasing hormone
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:7562510 PMID:7617693 PMID:8405091
NCBI chr 4:124,742,111...124,777,094
Ensembl chr 4:124,742,111...124,744,637
G
Prep
prolyl endopeptidase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:18318186
NCBI chr20:48,556,211...48,653,165
Ensembl chr20:48,556,280...48,654,466
G
Ptgs2
prostaglandin-endoperoxide synthase 2
IMP
RGD
PMID:18523723
RGD:2300277
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
G
Pomc
proopiomelanocortin
ISO
protein:increased expression:mammillary body
RGD
PMID:1650797
RGD:407572523
NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
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