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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:amnestic disorder
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Accession:DOID:10914 term browser browse the term
Definition:A cognitive disorder where the memory is disturbed or lost and involves the loss of memories previously established, loss of the ability to create new memories, or loss of the ability to learn new information. (DO)
Synonyms:exact_synonym: Amnesia Memory Loss;   Amnestic State;   Global Amnesia;   Hysterical Amnesia;   Hysterical Amnesias;   Korsakoff's psychosis or syndrome;   Tactile Amnesia;   Tactile Amnesias;   amnesia;   amnesias;   amnestic states;   amnestic syndrome;   global amnesias;   temporary amnesia;   temporary amnesias
 primary_id: MESH:D000647
 xref: EFO:1001454;   ICD10CM:R41.3;   ICD9CM:294.0;   NCI:C2867
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
amnestic disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:12642396 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Arc activity-regulated cytoskeleton-associated protein treatment ISO RGD PMID:24012642 RGD:401938610 NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378 		JBrowse link
G Avp arginine vasopressin ISO CTD Direct Evidence: therapeutic CTD PMID:7562510 NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425 		JBrowse link
G Bche butyrylcholinesterase IMP RGD PMID:21771623 RGD:5688134 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148 		JBrowse link
G Bdnf brain-derived neurotrophic factor treatment ISO
IEP		 protein:decreased expression:amygdala, hippocampus, prefrontal cortex RGD PMID:25061594 PMID:31400468 PMID:28716085 RGD:10059361, RGD:401960871, RGD:401960865 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Cartpt CART prepropeptide treatment IEP associated with morphine withdrawal syndrome RGD PMID:32198124 RGD:407571681 NCBI chr 2:31,255,098...31,257,452
Ensembl chr 2:31,255,098...31,290,713 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 treatment ISO
IDA		 protein:decreased phosphorylation:amygdala, hippocampus, prefrontal cortex RGD PMID:28716085 PMID:31400468 RGD:401960865, RGD:401960871 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Csf2 colony stimulating factor 2 ISO CTD Direct Evidence: therapeutic CTD PMID:8877002 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199 		JBrowse link
G Drd3 dopamine receptor D3 IMP RGD PMID:15619116 RGD:7175071 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596 		JBrowse link
G Gja1 gap junction protein, alpha 1 IMP RGD PMID:22665389 RGD:7207267 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Gnai1 G protein subunit alpha i1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11350863 NCBI chr 4:16,814,000...16,898,119
Ensembl chr 4:16,814,001...16,896,417 		JBrowse link
G Gnai3 G protein subunit alpha i3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11350863 NCBI chr 2:195,742,765...195,780,720
Ensembl chr 2:195,742,642...195,780,742 		JBrowse link
G Grp gastrin releasing peptide ISO CTD Direct Evidence: therapeutic CTD PMID:11564462 NCBI chr18:59,388,679...59,402,061
Ensembl chr18:59,388,274...59,402,061 		JBrowse link
G Hrh3 histamine receptor H3 IDA
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:11125734 PMID:17276409 RGD:1626421 NCBI chr 3:167,191,551...167,196,642
Ensembl chr 3:167,191,558...167,196,642 		JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 IMP RGD PMID:18570192 RGD:6482184 NCBI chr 1:233,636,442...233,761,063
Ensembl chr 1:233,636,452...233,760,626 		JBrowse link
G Il1a interleukin 1 alpha ISO CTD Direct Evidence: therapeutic CTD PMID:8003924 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il2 interleukin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8241462 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il6 interleukin 6 ISO CTD Direct Evidence: therapeutic CTD PMID:9189931 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Ngf nerve growth factor ISO CTD Direct Evidence: therapeutic CTD PMID:16405025 PMID:19694610 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Pdyn prodynorphin ISO CTD Direct Evidence: therapeutic CTD PMID:7768285 NCBI chr 3:116,900,990...116,913,334
Ensembl chr 3:116,900,992...116,913,334 		JBrowse link
G Pomc proopiomelanocortin ISO CTD Direct Evidence: marker/mechanism CTD PMID:2841920 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha IEP associated with morphine withdrawal syndrome;mRNA:increased expression:hippocamous (rat) RGD PMID:32198124 RGD:407571681 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
G Prep prolyl endopeptidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:8691432 NCBI chr20:48,556,211...48,653,165
Ensembl chr20:48,556,280...48,654,466 		JBrowse link
G Sigmar1 sigma non-opioid intracellular receptor 1 ISO CTD Direct Evidence: therapeutic CTD PMID:12028363 NCBI chr 5:56,904,155...56,907,012
Ensembl chr 5:56,904,159...56,907,017 		JBrowse link
G Tac1 tachykinin, precursor 1 ISO CTD Direct Evidence: therapeutic CTD PMID:7562510 PMID:9521815 PMID:20600432 NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178 		JBrowse link
G Trh thyrotropin releasing hormone ISO CTD Direct Evidence: therapeutic CTD PMID:7562510 PMID:7617693 PMID:8405091 NCBI chr 4:124,742,111...124,777,094
Ensembl chr 4:124,742,111...124,744,637 		JBrowse link
retrograde amnesia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prep prolyl endopeptidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:18318186 NCBI chr20:48,556,211...48,653,165
Ensembl chr20:48,556,280...48,654,466 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IMP RGD PMID:18523723 RGD:2300277 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
Wernicke-Korsakoff syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pomc proopiomelanocortin ISO protein:increased expression:mammillary body RGD PMID:1650797 RGD:407572523 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19099
    disease of anatomical entity 18440
      nervous system disease 14334
        Neurologic Manifestations 10420
          Neurobehavioral Manifestations 4693
            Memory Disorders 114
              amnestic disorder 28
                Alcohol Amnestic Disorder + 1
                anterograde amnesia 0
                dissociative amnesia 0
                retrograde amnesia 2
                transient global amnesia 0
Path 2
Term Annotations click to browse term
  disease 19099
    disease of anatomical entity 18440
      nervous system disease 14334
        central nervous system disease 12604
          brain disease 11833
            disease of mental health 8425
              cognitive disorder 2316
                amnestic disorder 28
                  Alcohol Amnestic Disorder + 1
                  anterograde amnesia 0
                  dissociative amnesia 0
                  retrograde amnesia 2
                  transient global amnesia 0
paths to the root