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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Signs and Symptoms
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Accession:DOID:9000071 term browser browse the term
Definition:Clinical manifestations that can be either objective when observed by a physician, or subjective when perceived by the patient.
Synonyms:primary_id: MESH:D012816;   RDO:0004930
For additional species annotation, visit the Alliance of Genome Resources.


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Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16058
    Pathological Conditions, Signs and Symptoms 8739
      Signs and Symptoms 5235
        Asthenia 1
        Body Temperature Changes + 78
        Body Weight + 960
        Cardiac Output, High 1
        Cardiac Output, Low 3
        Chills 1
        Cyanosis + 5
        Digestive Signs and Symptoms + 117
        Edema + 91
        Exercise Intolerance 2
        Eye Manifestations + 4
        Failure to Thrive + 35
        Fatigue + 9
        Feminization 1
        Fetal Distress 3
        Flushing + 6
        Heart Murmurs + 1
        Hot Flashes 2
        Hypergammaglobulinemia + 15
        Hyperlactatemia 0
        Hypertriglyceridemic Waist 0
        Medically Unexplained Symptoms 0
        Mobility Limitation 19
        Neurologic Manifestations + 4189
        Oral Manifestations + 2
        Polydipsia + 1
        Premature Aging + 66
        Prodromal Symptoms 0
        Pseudophakia 0
        Renal Colic 1
        Reticulocytosis 4
        Signs and Symptoms, Respiratory + 225
        Skin Manifestations + 147
        Slow Coronary Flow 1
        Urological Manifestations + 533
        Virilism + 9
        intermittent claudication 9
        motion sickness + 0
        myocardial stunning 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.