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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Signs and Symptoms
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Accession:DOID:9000071 term browser browse the term
Definition:Clinical manifestations that can be either objective when observed by a physician, or subjective when perceived by the patient.
Synonyms:primary_id: MESH:D012816;   RDO:0004930
For additional species annotation, visit the Alliance of Genome Resources.


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  • Term paths to the root
    Path 1
    Term Annotations click to browse term
      disease 17207
        Pathological Conditions, Signs and Symptoms 10235
          Signs and Symptoms 6499
            Asthenia 1
            Body Temperature Changes + 92
            Body Weight + 943
            Cardiac Output, High 1
            Cardiac Output, Low 3
            Chills 1
            Cyanosis + 5
            Digestive Signs and Symptoms + 117
            Edema + 111
            Exercise Intolerance 3
            Eye Manifestations + 4
            Failure to Thrive + 28
            Fatigue + 8
            Feminization 1
            Fetal Distress 3
            Flushing + 6
            Heart Murmurs + 0
            Hot Flashes 2
            Hypergammaglobulinemia + 17
            Hyperlactatemia 0
            Hypertriglyceridemic Waist 0
            Medically Unexplained Symptoms 0
            Mobility Limitation 7
            Neurologic Manifestations + 5446
            Oral Manifestations + 2
            Polydipsia + 1
            Premature Aging + 75
            Prodromal Symptoms 0
            Pseudophakia 0
            Renal Colic 1
            Reticulocytosis 4
            Signs and Symptoms, Respiratory + 233
            Skin Manifestations + 126
            Slow Coronary Flow 1
            Urological Manifestations + 587
            Virilism + 12
            intermittent claudication 9
            motion sickness + 0
            myocardial stunning 4
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