The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:
EC 1.14.11.* (oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors) inhibitor
An EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the function of any such enzyme using 2-oxoglutarate as one donor and incorporating one atom each of oxygen into both donors (EC 1.14.11.*).
Synonyms:
related_synonym:
EC 1.14.11.* inhibitor; EC 1.14.11.* inhibitors; oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors (EC 1.14.11.*) inhibitors; oxidoreductase acting on paired donors, with 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors (EC 1.14.11.*) inhibitor; oxidoreductase acting on paired donors, with 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors (EC 1.14.11.*) inhibitors
protocatechuic acid inhibits the reaction [sodium arsenite results in decreased activity of ACHE protein] protocatechuic acid inhibits the reaction [Cadmium Chloride results in increased activity of ACHE protein]
Gallic Acid inhibits the reaction [protocatechuic acid inhibits the reaction [APP protein modified form binds to APP protein modified form]]; protocatechuic acid inhibits the reaction [APP protein modified form binds to APP protein modified form]
protocatechuic acid inhibits the reaction [sodium arsenite results in increased expression of BAX mRNA]; protocatechuic acid inhibits the reaction [sodium arsenite results in increased expression of BAX protein] protocatechuic acid inhibits the reaction [Cadmium Chloride results in increased expression of BAX mRNA]; protocatechuic acid inhibits the reaction [Isoproterenol results in increased expression of BAX protein]
protocatechuic acid inhibits the reaction [Cadmium Chloride results in decreased expression of BCL2 mRNA]; protocatechuic acid inhibits the reaction [Cadmium Chloride results in decreased expression of BCL2 protein]; protocatechuic acid inhibits the reaction [Isoproterenol results in decreased expression of BCL2 protein]; protocatechuic acid inhibits the reaction [Rotenone results in decreased expression of BCL2 protein] protocatechuic acid inhibits the reaction [sodium arsenite results in decreased expression of BCL2 mRNA]; protocatechuic acid inhibits the reaction [sodium arsenite results in decreased expression of BCL2 protein]
protocatechuic acid inhibits the reaction [sodium arsenite results in decreased expression of BDNF protein] protocatechuic acid inhibits the reaction [Cadmium Chloride results in decreased expression of BDNF protein]
protocatechuic acid inhibits the reaction [Cadmium Chloride results in increased activity of CASP3 protein]; protocatechuic acid inhibits the reaction [Cadmium Chloride results in increased expression of CASP3 mRNA]; protocatechuic acid inhibits the reaction [furan results in increased activity of CASP3 protein]; protocatechuic acid inhibits the reaction [Isoproterenol results in increased activity of CASP3 protein]; protocatechuic acid inhibits the reaction [Rotenone results in increased activity of CASP3 protein] protocatechuic acid inhibits the reaction [sodium arsenite results in increased activity of CASP3 protein]; protocatechuic acid inhibits the reaction [sodium arsenite results in increased expression of CASP3 mRNA]
protocatechuic acid results in increased activity of CAT protein protocatechuic acid inhibits the reaction [Lipopolysaccharides results in decreased expression of CAT protein]; protocatechuic acid inhibits the reaction [sodium arsenite results in decreased activity of CAT protein]; protocatechuic acid inhibits the reaction [sodium arsenite results in decreased expression of CAT mRNA] protocatechuic acid inhibits the reaction [Cadmium Chloride results in decreased activity of CAT protein]; protocatechuic acid inhibits the reaction [Cadmium Chloride results in decreased expression of CAT mRNA]; protocatechuic acid inhibits the reaction [furan results in decreased activity of CAT protein]; protocatechuic acid inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]
protocatechuic acid inhibits the reaction [bisphenol A results in decreased expression of CYP11A1 mRNA]; protocatechuic acid inhibits the reaction [bisphenol A results in decreased expression of CYP11A1 protein]
[protocatechuic acid co-treated with Methylcholanthrene] results in decreased activity of CYP2E1 protein; protocatechuic acid inhibits the reaction [bisphenol A results in increased expression of CYP2E1 mRNA] protocatechuic acid results in decreased activity of CYP2E1 protein
protocatechuic acid results in increased expression of EPO protein protocatechuic acid inhibits the reaction [methylmercuric chloride results in decreased expression of EPO protein]; protocatechuic acid inhibits the reaction [Methylmercury Compounds results in decreased expression of EPO protein]
protocatechuic acid results in increased expression of FSHB protein protocatechuic acid inhibits the reaction [furan results in decreased expression of FSHB protein]
protocatechuic acid results in increased activity of G6PD protein protocatechuic acid inhibits the reaction [furan results in decreased activity of G6PD protein]
protocatechuic acid results in increased expression of GPX1 mRNA protocatechuic acid inhibits the reaction [sodium arsenite results in decreased expression of GPX1 mRNA] protocatechuic acid inhibits the reaction [Cadmium Chloride results in decreased expression of GPX1 mRNA]
protocatechuic acid inhibits the reaction [sodium arsenite results in decreased activity of GSR protein]; protocatechuic acid inhibits the reaction [sodium arsenite results in decreased expression of GSR mRNA] protocatechuic acid results in increased activity of GSR protein protocatechuic acid results in increased expression of GSR mRNA protocatechuic acid inhibits the reaction [Cadmium Chloride results in decreased expression of GSR mRNA]; protocatechuic acid inhibits the reaction [Isoproterenol results in decreased activity of GSR protein]
protocatechuic acid results in increased stability of HIF1A protein protocatechuic acid inhibits the reaction [methylmercuric chloride results in decreased expression of HIF1A protein]; protocatechuic acid inhibits the reaction [Methylmercury Compounds results in decreased expression of HIF1A protein] protocatechuic acid results in increased expression of HIF1A protein
protocatechuic acid inhibits the reaction [Isoproterenol results in decreased expression of HMOX1 mRNA] protocatechuic acid results in increased expression of HMOX1 mRNA
protocatechuic acid inhibits the reaction [Galactose results in increased secretion of IL1B protein]; protocatechuic acid inhibits the reaction [sodium arsenite results in increased expression of IL1B mRNA]; protocatechuic acid inhibits the reaction [sodium arsenite results in increased expression of IL1B protein] protocatechuic acid inhibits the reaction [Cadmium Chloride results in increased expression of IL1B mRNA]; protocatechuic acid inhibits the reaction [Cadmium Chloride results in increased expression of IL1B protein]; protocatechuic acid inhibits the reaction [furan results in increased expression of IL1B protein]; protocatechuic acid inhibits the reaction [Isoproterenol results in increased expression of IL1B protein]
protocatechuic acid results in increased expression of LHB protein protocatechuic acid inhibits the reaction [furan results in decreased expression of LHB protein]
protocatechuic acid results in increased activity of MPO protein protocatechuic acid results in decreased activity of MPO protein protocatechuic acid inhibits the reaction [furan results in increased activity of MPO protein]
[protocatechuic acid co-treated with Cadmium Chloride] results in increased expression of NFE2L2 mRNA; protocatechuic acid inhibits the reaction [Isoproterenol results in decreased expression of NFE2L2 mRNA] protocatechuic acid results in increased expression of NFE2L2 mRNA protocatechuic acid inhibits the reaction [Lipopolysaccharides results in decreased expression of NFE2L2 mRNA]
protocatechuic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of NFKBIB protein]
protocatechuic acid inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein] which results in increased abundance of Nitrites]; protocatechuic acid inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; protocatechuic acid inhibits the reaction [sodium arsenite results in increased expression of NOS2 mRNA]; protocatechuic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein] protocatechuic acid inhibits the reaction [Cadmium Chloride results in increased expression of NOS2 mRNA]
[protocatechuic acid co-treated with Methylcholanthrene] results in increased activity of NQO1 protein protocatechuic acid results in increased activity of NQO1 protein protocatechuic acid inhibits the reaction [Lipopolysaccharides results in decreased expression of NQO1 mRNA]
protocatechuic acid inhibits the reaction [Galactose results in increased expression of PTGS2 mRNA]; protocatechuic acid inhibits the reaction [Galactose results in increased expression of PTGS2 protein]; protocatechuic acid inhibits the reaction [Lipopolysaccharides results in decreased expression of PTGS2 protein]; protocatechuic acid inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; protocatechuic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of and results in increased expression of PTGS2 protein]
protocatechuic acid inhibits the reaction [Galactose results in increased expression of and results in increased activity of RELA protein]; protocatechuic acid inhibits the reaction [Galactose results in increased expression of RELA mRNA]; protocatechuic acid inhibits the reaction [Galactose results in increased expression of RELA protein]; protocatechuic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein] protocatechuic acid inhibits the reaction [Isoproterenol results in increased expression of RELA protein]
protocatechuic acid results in increased expression of SLC2A1 protein protocatechuic acid inhibits the reaction [methylmercuric chloride results in decreased expression of SLC2A1 protein]; protocatechuic acid inhibits the reaction [Methylmercury Compounds results in decreased expression of SLC2A1 protein]
protocatechuic acid inhibits the reaction [sodium arsenite results in decreased expression of SOD2 mRNA] protocatechuic acid results in increased expression of SOD2 mRNA protocatechuic acid inhibits the reaction [Cadmium Chloride results in decreased expression of SOD2 mRNA]
protocatechuic acid inhibits the reaction [bisphenol A results in decreased expression of STAR mRNA]; protocatechuic acid inhibits the reaction [bisphenol A results in decreased expression of STAR protein]
protocatechuic acid inhibits the reaction [Galactose results in increased secretion of TNF protein]; protocatechuic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; protocatechuic acid inhibits the reaction [sodium arsenite results in increased expression of TNF mRNA]; protocatechuic acid inhibits the reaction [sodium arsenite results in increased expression of TNF protein] protocatechuic acid inhibits the reaction [TNF protein results in increased expression of SELE protein] protocatechuic acid inhibits the reaction [Cadmium Chloride results in increased expression of TNF mRNA]; protocatechuic acid inhibits the reaction [Cadmium Chloride results in increased expression of TNF protein]; protocatechuic acid inhibits the reaction [furan results in increased expression of TNF protein]; protocatechuic acid inhibits the reaction [Isoproterenol results in increased expression of TNF protein]
protocatechuic acid results in increased expression of VEGFA protein protocatechuic acid inhibits the reaction [methylmercuric chloride results in decreased expression of VEGFA protein]; protocatechuic acid inhibits the reaction [Methylmercury Compounds results in decreased expression of VEGFA protein]
ethyl protocatechuate inhibits the reaction [rosiglitazone results in increased ubiquitination of and results in increased degradation of GATA3 protein]
ethyl protocatechuate inhibits the reaction [rosiglitazone results in increased ubiquitination of and results in increased degradation of KLF2 protein]
ethyl protocatechuate inhibits the reaction [Ascorbic Acid results in increased expression of SP7 mRNA]; ethyl protocatechuate inhibits the reaction [Ascorbic Acid results in increased expression of SP7 protein]
ethyl protocatechuate inhibits the reaction [Rosiglitazone results in increased ubiquitination of and results in increased degradation of TAFAZZIN protein]
[Cadmium Chloride results in increased abundance of Cadmium] inhibits the reaction [roxadustat results in increased activity of HIF1A protein] roxadustat promotes the reaction [Hyaluronic Acid results in increased expression of HIF1A protein]