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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2275
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp3
Name: caspase 3
Acc ID: CHEBI:36062
Term: 3,4-dihydroxybenzoic acid
Definition: A dihydroxybenzoic acid in which the hydroxy groups are located at positions 3 and 4.
Chemical ID: MESH:C009091
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp3multiple interactionsEXP 6480464CTDprotocatechuic acid inhibits the reaction [Cadmium Chloride results in increased activity of CASP3 protein]; protocatechuic acid inhibits the reaction [Cadmium Chloride results in increased expression of CASP3 mRNA]; protocatechuic acid inhibits the reaction [furan results in increased activity of CASP3 protein]; protocatechuic acid inhibits the reaction [Isoproterenol results in increased activity of CASP3 protein]; protocatechuic acid inhibits the reaction [Rotenone results in increased activity of CASP3 protein]PMID:18082360 PMID:32392679 PMID:32758512 PMID:36593721
Casp3multiple interactionsISOCasp3 (Mus musculus)6480464CTDprotocatechuic acid inhibits the reaction [sodium arsenite results in increased activity of CASP3 protein]; protocatechuic acid inhibits the reaction [sodium arsenite results in increased expression of CASP3 mRNA]PMID:33497687
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