The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
[cumene co-treated with KRAS gene mutant form] results in decreased expression of CCN1 mRNA; [cumene co-treated with KRAS gene mutant form] results in decreased expression of CEBPD mRNA; [cumene co-treated with KRAS gene mutant form] results in decreased expression of CKS1B mRNA; [cumene co-treated with KRAS gene mutant form] results in decreased expression of DLC1 mRNA; [cumene co-treated with KRAS gene mutant form] results in decreased expression of DUSP14 mRNA; [cumene co-treated with KRAS gene mutant form] results in decreased expression of DUSP3 mRNA; [cumene co-treated with KRAS gene mutant form] results in decreased expression of ENO1 mRNA; [cumene co-treated with KRAS gene mutant form] results in decreased expression of ENPP2 mRNA; [cumene co-treated with KRAS gene mutant form] results in decreased expression of EPCAM mRNA; [cumene co-treated with KRAS gene mutant form] results in decreased expression of GPER1 mRNA; [cumene co-treated with KRAS gene mutant form] results in decreased expression of IGFBP4 mRNA; [cumene co-treated with KRAS gene mutant form] results in decreased expression of KRT18 mRNA; [cumene co-treated with KRAS gene mutant form] results in decreased expression of KRT8 mRNA; [cumene co-treated with KRAS gene mutant form] results in decreased expression of LASP1 mRNA; [cumene co-treated with KRAS gene mutant form] results in decreased expression of MMP14 mRNA; [cumene co-treated with KRAS gene mutant form] results in decreased expression of RACK1 mRNA; [cumene co-treated with KRAS gene mutant form] results in decreased expression of RB1 mRNA; [cumene co-treated with KRAS gene mutant form] results in decreased expression of SDC1 mRNA; [cumene co-treated with KRAS gene mutant form] results in decreased expression of SLC2A1 mRNA; [cumene co-treated with KRAS gene mutant form] results in decreased expression of SOD3 mRNA; [cumene co-treated with KRAS gene mutant form] results in decreased expression of SRD5A1 mRNA; [cumene co-treated with KRAS gene mutant form] results in decreased expression of VWF mRNA; [cumene co-treated with KRAS gene mutant form] results in increased expression of AREG mRNA; [cumene co-treated with KRAS gene mutant form] results in increased expression of CCND1 mRNA; [cumene co-treated with KRAS gene mutant form] results in increased expression of EREG mRNA; [cumene co-treated with KRAS gene mutant form] results in increased expression of KLF5 mRNA; [cumene co-treated with KRAS gene mutant form] results in increased expression of LAMTOR2 mRNA; [cumene co-treated with KRAS gene mutant form] results in increased expression of MAP2K1 mRNA; [cumene co-treated with KRAS gene mutant form] results in increased expression of MAP2K1 protein; [cumene co-treated with KRAS gene mutant form] results in increased expression of MIF mRNA; [cumene co-treated with KRAS gene mutant form] results in increased expression of PTGES mRNA; KRAS gene mutant form promotes the reaction [cumene results in increased expression of CLU mRNA]
[cumene co-treated with KRAS gene mutant form] results in increased expression of MAP2K1 mRNA; [cumene co-treated with KRAS gene mutant form] results in increased expression of MAP2K1 protein
4-isopropylphenol binds to and results in increased activity of ESRRG protein; 4-isopropylphenol inhibits the reaction [afimoxifene binds to and results in decreased activity of ESRRG protein] 4-isopropylphenol binds to ESRRG protein
cumene hydroperoxide results in decreased activity of CAT protein cumene hydroperoxide results in increased activity of CAT protein Iron promotes the reaction [cumene hydroperoxide results in decreased activity of CAT protein]; Iron-Dextran Complex promotes the reaction [cumene hydroperoxide results in decreased activity of CAT protein]
[[CYP2S1 protein co-treated with cumene hydroperoxide] results in increased oxidation of benzo(a)pyrene 7,8-dihydrodiol] which results in increased abundance of benzo(a)pyrene-7,8,9,10-tetrol; [[CYP2S1 protein co-treated with cumene hydroperoxide] results in increased oxidation of Benzo(a)pyrene] which results in increased abundance of benzo(a)pyrene-1,6-quinone; [[CYP2S1 protein co-treated with cumene hydroperoxide] results in increased oxidation of Benzo(a)pyrene] which results in increased abundance of benzo(a)pyrene-3,6-quinone; [[CYP2S1 protein co-treated with cumene hydroperoxide] results in increased oxidation of Benzo(a)pyrene] which results in increased abundance of benzo(a)pyrene-6,12-quinone; [CYP2S1 protein co-treated with cumene hydroperoxide] results in increased oxidation of 9,10-dihydrobenzo(a)pyrene; [CYP2S1 protein co-treated with cumene hydroperoxide] results in increased oxidation of 9,10-Dimethyl-1,2-benzanthracene; [CYP2S1 protein co-treated with cumene hydroperoxide] results in increased oxidation of Aflatoxin B1; [CYP2S1 protein co-treated with cumene hydroperoxide] results in increased oxidation of Benzo(a)pyrene; [CYP2S1 protein co-treated with cumene hydroperoxide] results in increased oxidation of benzo(a)pyrene 7,8-dihydrodiol; [CYP2S1 protein co-treated with cumene hydroperoxide] results in increased oxidation of Tretinoin
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [cumene hydroperoxide results in decreased expression of EEF2 protein]; Vitamin E analog inhibits the reaction [cumene hydroperoxide results in decreased expression of EEF2 protein] cumene hydroperoxide results in decreased expression of EEF2; cumene hydroperoxide results in decreased expression of EEF2 protein
GPX1 protein results in decreased susceptibility to cumene hydroperoxide GPX1 protein results in increased reduction of cumene hydroperoxide GPX1 protein results in increased metabolism of cumene hydroperoxide
GSTA2 protein polymorphism results in decreased metabolism of cumene hydroperoxide GSTA2 protein results in increased metabolism of cumene hydroperoxide
GSTM3 protein polymorphism results in decreased metabolism of cumene hydroperoxide GSTM3 protein polymorphism results in increased metabolism of cumene hydroperoxide
alpha-Tocopherol inhibits the reaction [cumene hydroperoxide results in decreased uptake of GUSB protein]; alpha-Tocopherol inhibits the reaction [cumene hydroperoxide results in increased secretion of GUSB protein]
[KEAP1 gene mutant form results in increased activity of NFE2L2] which results in decreased susceptibility to cumene hydroperoxide; Buthionine Sulfoximine inhibits the reaction [[KEAP1 gene mutant form results in increased activity of NFE2L2] which results in decreased susceptibility to cumene hydroperoxide]
NFE2L2 gene mutant form results in increased susceptibility to cumene hydroperoxide [KEAP1 gene mutant form results in increased activity of NFE2L2] which results in decreased susceptibility to cumene hydroperoxide; Buthionine Sulfoximine inhibits the reaction [[KEAP1 gene mutant form results in increased activity of NFE2L2] which results in decreased susceptibility to cumene hydroperoxide] Buthionine Sulfoximine inhibits the reaction [NFE2L2 protein promotes the reaction [sulforaphane results in decreased susceptibility to cumene hydroperoxide]]; NFE2L2 protein promotes the reaction [sulforaphane results in decreased susceptibility to cumene hydroperoxide] [NFE2L2 affects the susceptibility to sulforaphane] which affects the susceptibility to cumene hydroperoxide
cumene hydroperoxide results in increased activity of ODC1 protein Iron promotes the reaction [cumene hydroperoxide results in increased activity of ODC1 protein]; Iron-Dextran Complex promotes the reaction [cumene hydroperoxide results in increased activity of ODC1 protein]
cumene hydroperoxide results in increased expression of PTGS2 protein [cumene hydroperoxide results in increased expression of PTGS2 protein] which results in increased abundance of Dinoprostone; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [cumene hydroperoxide results in increased expression of PTGS2 protein]