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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:4-isopropylphenol
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Accession:CHEBI:167172 term browser browse the term
Definition:A member of the class of phenols that is phenol which is carrying an isopropyl group at position 4.
Synonyms:exact_synonym: 4-(propan-2-yl)phenol
 related_synonym: 1-hydroxy-4-isopropylbenzene;   4-(1-methylethyl)phenol;   4-hydroxycumene;   Formula=C9H12O;   InChI=1S/C9H12O/c1-7(2)8-3-5-9(10)6-4-8/h3-7,10H,1-2H3;   InChIKey=YQUQWHNMBPIWGK-UHFFFAOYSA-N;   SMILES=CC(C)C1=CC=C(O)C=C1;   p-cumenol;   p-hydroxycumene;   p-isopropylphenol
 xref: CAS:99-89-8;   Chemspider:7185;   FooDB:FDB005302;   HMDB:HMDB0031446
 xref_mesh: MESH:C028690
 xref: PMID:16567400;   PMID:26219367;   PMID:27486708;   PMID:29225186;   PMID:30519707;   PMID:32970353;   Reaxys:1363564


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4-isopropylphenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO 4-isopropylphenol inhibits the reaction [Dihydrotestosterone binds to and results in increased activity of AR protein] CTD PMID:27561732 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 increases glutathionylation ISO CYP2C8 protein results in increased glutathionylation of 4-isopropylphenol CTD PMID:23470418 NCBI chr 1:147,236,480...147,307,988 JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 increases glutathionylation ISO CYP3A4 protein results in increased glutathionylation of 4-isopropylphenol CTD PMID:23470418 NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
JBrowse link
G Esrrg estrogen-related receptor gamma multiple interactions
affects binding
ISO 4-isopropylphenol binds to and results in increased activity of ESRRG protein; 4-isopropylphenol inhibits the reaction [afimoxifene binds to and results in decreased activity of ESRRG protein]
4-isopropylphenol binds to ESRRG protein
CTD PMID:27486708 PMID:31127318 NCBI chr13:106,063,799...106,683,353
Ensembl chr13:106,463,368...106,683,436
JBrowse link
G LOC686683 similar to olfactory receptor 73 multiple interactions ISO 4-isopropylphenol binds to and results in increased activity of OLFR73 protein CTD PMID:21142015 NCBI chr 3:76,186,104...76,187,045
Ensembl chr 3:76,186,104...76,187,045
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19761
    role 19711
      application 19401
        food additive 14749
          flavouring agent 1842
            4-isopropylphenol 5
              4-isopropylphenyl sulfate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19761
    subatomic particle 19759
      composite particle 19759
        hadron 19759
          baryon 19759
            nucleon 19759
              atomic nucleus 19759
                atom 19759
                  main group element atom 19653
                    main group molecular entity 19653
                      s-block molecular entity 19418
                        hydrogen molecular entity 19411
                          hydrides 18751
                            organic hydride 18352
                              organic fundamental parent 18352
                                hydrocarbon 18071
                                  cyclic hydrocarbon 17087
                                    monocyclic hydrocarbon 5815
                                      annulene 5641
                                        aromatic annulene 5641
                                          benzene 5641
                                            alkylbenzene 3363
                                              cumene 101
                                                4-isopropylphenol 5
                                                  4-isopropylphenyl sulfate 0
paths to the root