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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:lung adenocarcinoma
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Accession:DOID:3910 term browser browse the term
Definition:A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin. (DO)
Synonyms:exact_synonym: LUAD;   adenocarcinoma of lung;   bronchogenic lung adenocarcinoma;   non-small cell lung adenocarcinoma;   nonsmall cell adenocarcinoma;   pulmonary adenocarcinoma
 related_synonym: adenocarcinoma of lung, somatic
 primary_id: MESH:D000077192
 xref: EFO:0000571;   EFO:0005288;   GARD:5742;   NCI:C129299;   NCI:C27745;   NCI:C3512
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
lung adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCE1 ATP binding cassette subfamily E member 1 severity ISO mRNA, protein:increased expression:lung (human) RGD PMID:18788636 RGD:11046260 NCBI chr15:43,781,838...43,813,529
Ensembl chr15:43,781,885...43,811,883 		JBrowse link
G ACSL4 acyl-CoA synthetase long chain family member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr  X:82,864,506...82,943,984
Ensembl chr  X:82,866,823...82,916,789 		JBrowse link
G ADAM19 ADAM metallopeptidase domain 19 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr 4:52,650,077...52,733,299
Ensembl chr 4:52,650,162...52,729,843 		JBrowse link
G ADAM28 ADAM metallopeptidase domain 28 disease_progression
exacerbates
treatment		 ISO protein:increased expression:lung RGD PMID:20112342 PMID:26800504 PMID:29882245 PMID:30190423 RGD:11531771 RGD:153297792 RGD:153297794 RGD:153297795 NCBI chr25:33,092,645...33,147,791
Ensembl chr25:33,092,628...33,264,710 		JBrowse link
G ADAMTSL3 ADAMTS like 3 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr 3:55,358,869...55,695,198
Ensembl chr 3:55,357,888...55,693,167 		JBrowse link
G ADGRG6 adhesion G protein-coupled receptor G6 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr 1:33,967,783...34,106,950
Ensembl chr 1:33,969,268...34,104,228 		JBrowse link
G AHCY adenosylhomocysteinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr24:23,410,553...23,423,494
Ensembl chr24:23,411,140...23,419,767 		JBrowse link
G AHR aryl hydrocarbon receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:12597446 NCBI chr14:31,743,704...31,793,484
Ensembl chr14:31,686,170...31,791,444 		JBrowse link
G AKR1A1 aldo-keto reductase family 1 member A1 disease_progression ISO RGD PMID:30727821 RGD:27226687 NCBI chr15:14,792,398...14,808,805
Ensembl chr15:14,742,012...14,808,592 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 ISO ClinVar Annotator: match by term: Adenocarcinoma of lung ClinVar PMID:17611497 PMID:18256540 PMID:18392055 PMID:18504432 PMID:18611285 More... NCBI chr 8:72,317,399...72,335,686
Ensembl chr 8:72,317,869...72,335,193 		JBrowse link
G ALB albumin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr13:62,133,747...62,169,349
Ensembl chr13:62,053,814...62,294,709 		JBrowse link
G ALDH18A1 aldehyde dehydrogenase 18 family member A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr28:9,101,578...9,148,063
Ensembl chr28:9,102,282...9,147,992 		JBrowse link
G ALDOA aldolase, fructose-bisphosphate A ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr 6:18,077,241...18,083,053 JBrowse link
G ALK ALK receptor tyrosine kinase ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:18923525 PMID:20979473 PMID:21030459 PMID:21575866 PMID:21791641 More... NCBI chr17:23,010,308...23,688,841
Ensembl chr17:23,010,308...23,688,841 		JBrowse link
G ALOX12B arachidonate 12-lipoxygenase, 12R type ISO CTD Direct Evidence: marker/mechanism CTD PMID:30258081 NCBI chr 5:32,899,416...32,911,442
Ensembl chr 5:32,896,238...32,911,552 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:30258081 NCBI chr28:2,170,920...2,218,765
Ensembl chr28:2,170,920...2,219,609 		JBrowse link
G ALX1 ALX homeobox 1 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr15:26,838,615...26,858,786
Ensembl chr15:26,834,670...26,858,803 		JBrowse link
G ALX4 ALX homeobox 4 disease_progression ISO RGD PMID:18978557 RGD:153350135 NCBI chr18:44,922,042...44,967,557
Ensembl chr18:44,922,150...44,967,550 		JBrowse link
G ANAPC2 anaphase promoting complex subunit 2 severity ISO mRNA:decreased expression:lung (human) RGD PMID:12036940 RGD:14696682 NCBI chr 9:48,475,777...48,486,715
Ensembl chr 9:48,471,584...48,609,303 		JBrowse link
G ANP32A acidic nuclear phosphoprotein 32 family member A ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr30:32,741,582...32,778,883
Ensembl chr30:32,741,582...32,798,188 		JBrowse link
G ANXA1 annexin A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr 1:84,744,159...84,763,011
Ensembl chr 1:84,744,163...84,763,011 		JBrowse link
G ANXA5 annexin A5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr19:18,419,936...18,450,088
Ensembl chr19:18,407,587...18,570,378 		JBrowse link
G APC APC regulator of WNT signaling pathway ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:1316610 PMID:1338764 PMID:2281069 PMID:8187091 PMID:8381579 More... NCBI chr 3:252,052...380,506
Ensembl chr 3:253,081...322,993 		JBrowse link
G APEX1 apurinic/apyrimidinic endodeoxyribonuclease 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr15:17,786,808...17,789,422
Ensembl chr15:17,786,357...17,789,422 		JBrowse link
G APOA1 apolipoprotein A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr 5:16,740,071...16,742,081
Ensembl chr 5:16,740,130...16,741,943 		JBrowse link
G APOC3 apolipoprotein C3 ISO protein:altered glycosylation:: RGD PMID:19322776 RGD:153344619 NCBI chr 5:16,744,423...16,746,992
Ensembl chr 5:16,744,423...16,746,992 		JBrowse link
G AQP4 aquaporin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 7:61,855,617...61,868,953
Ensembl chr 7:61,855,744...61,865,089 		JBrowse link
G ARAF A-Raf proto-oncogene, serine/threonine kinase ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:24569458 PMID:26619011 NCBI chr  X:41,180,082...41,191,579
Ensembl chr  X:41,180,250...41,191,310 		JBrowse link
G ARG1 arginase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr12:242,717...255,736
Ensembl chr12:242,714...255,305 		JBrowse link
G ARHGAP35 Rho GTPase activating protein 35 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr 1:108,952,836...109,034,329
Ensembl chr 1:108,952,562...109,034,337 		JBrowse link
G ARHGAP44 Rho GTPase activating protein 44 ISO mRNA:decreased expression:lung (human) RGD PMID:28527113 RGD:401901290 NCBI chr 5:36,790,059...36,957,932
Ensembl chr 5:36,789,814...36,957,411 		JBrowse link
G ATRX ATRX chromatin remodeler disease_progression ISO RGD PMID:31374064 RGD:127285382 NCBI chr  X:59,772,067...60,107,016
Ensembl chr  X:59,774,585...60,106,980 		JBrowse link
G AXIN2 axin 2 susceptibility
disease_progression		 ISO DNA:SNP:cds:p.P50S(human)
DNA:SNPs::1712 +19 G>A,148 C>T(human)		 RGD PMID:16820935 PMID:30346805 RGD:151356655 RGD:151356657 NCBI chr 9:14,559,476...14,588,950
Ensembl chr 9:14,559,388...14,588,530 		JBrowse link
G AZGP1 alpha-2-glycoprotein 1, zinc-binding ISO mRNA,protein:increased expression:lung RGD PMID:17724461 RGD:153350134 NCBI chr 6:9,622,991...9,629,154
Ensembl chr 6:9,622,992...9,629,154 		JBrowse link
G B2M beta-2-microglobulin ISO ClinVar Annotator: match by term: Adenocarcinoma of lung ClinVar PMID:26619011 NCBI chr30:11,331,574...11,337,991
Ensembl chr30:11,331,569...11,337,997 		JBrowse link
G BAP1 BRCA1 associated protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231345 NCBI chr20:37,355,499...37,364,298
Ensembl chr20:37,355,494...37,511,125 		JBrowse link
G BHLHE41 basic helix-loop-helix family member e41 ISO mRNA:decreased expression:lung (human) RGD PMID:18223678 RGD:151665316 NCBI chr27:21,464,302...21,469,119 JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 exacerbates ISO mRNA:increased expression:B cell (human) RGD PMID:33098370 RGD:153323293 NCBI chr 5:29,324,893...29,343,322
Ensembl chr 5:29,325,331...29,337,240 		JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 ameliorates
disease_progression		 ISO mRNA:increased expression:lung (human) RGD PMID:31964418 RGD:153344516 NCBI chr 9:2,930,308...2,959,307 JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:12068308 PMID:12198537 PMID:12447372 PMID:12460918 PMID:12460919 More... NCBI chr16:8,222,909...8,318,179
Ensembl chr16:8,222,907...8,317,906 		JBrowse link
G BTK Bruton tyrosine kinase exacerbates
susceptibility		 ISO mRNA:decreased expression:lung (human) RGD PMID:31803536 PMID:32351880 RGD:151347848 RGD:151347849 NCBI chr  X:75,270,952...75,302,663
Ensembl chr  X:75,270,979...75,302,562 		JBrowse link
G BZW2 basic leucine zipper and W2 domains 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr14:31,154,285...31,217,193
Ensembl chr14:31,153,659...31,216,911 		JBrowse link
G CADM1 cell adhesion molecule 1 ISO DNA, mRNA:hypermethylation, decreased expression:promoter:liver RGD PMID:16814249 RGD:2289096 NCBI chr 5:17,865,317...18,190,855
Ensembl chr 5:17,864,453...18,194,694 		JBrowse link
G CALR calreticulin treatment ISO human cells and recombinant gene in a mouse model RGD PMID:18245558 RGD:150521698 NCBI chr20:49,251,390...49,255,291
Ensembl chr20:49,251,777...49,255,245 		JBrowse link
G CAPG capping actin protein, gelsolin like ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr17:39,619,429...39,640,944
Ensembl chr17:39,619,248...39,640,942 		JBrowse link
G CBX5 chromobox 5 disease_progression ISO mRNA,protein:increased expression:lung: RGD PMID:22900142 RGD:9586743 NCBI chr27:1,020,500...1,058,027
Ensembl chr27:1,039,594...1,049,788 		JBrowse link
G CBX7 chromobox 7 ISO mRNA,DNA:decreased expression, loss of heterozygosity:lung: RGD PMID:22214847 RGD:9587356 NCBI chr10:25,876,022...25,896,284
Ensembl chr10:25,876,016...25,893,501 		JBrowse link
G CCND1 cyclin D1 treatment
disease_progression		 ISO RGD PMID:19355812 PMID:26681199 RGD:11536846 RGD:13434927 NCBI chr18:48,501,905...48,509,684
Ensembl chr18:48,501,899...48,516,005 		JBrowse link
G CCND2 cyclin D2 disease_progression ISO RGD PMID:30308939 RGD:151665105 NCBI chr27:40,563,306...40,593,362
Ensembl chr27:40,564,921...40,594,255 		JBrowse link
G CCT5 chaperonin containing TCP1 subunit 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr34:4,035,851...4,049,131
Ensembl chr34:4,035,857...4,049,244 		JBrowse link
G CD163 CD163 molecule ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr27:37,669,757...37,700,746
Ensembl chr27:37,669,827...37,753,106 		JBrowse link
G CD44 CD44 molecule disease_progression ISO mRNA:splice variants:lung
mRNA:increased expression:lung (human)		 RGD PMID:18091389 PMID:29537891 RGD:149735539 RGD:2289345 NCBI chr18:32,735,493...32,826,483
Ensembl chr18:32,737,907...32,827,107 		JBrowse link
G CDC73 cell division cycle 73 exacerbates ISO mRNA:decreased expression:lung (human) RGD PMID:21692036 RGD:150537041 NCBI chr38:5,826,209...5,937,930
Ensembl chr38:5,805,916...5,938,111 		JBrowse link
G CDH1 cadherin 1 ISO DNA:increased methylation RGD PMID:16329148 RGD:1599556 NCBI chr 5:80,757,508...80,834,878
Ensembl chr 5:80,757,508...80,834,878 		JBrowse link
G CDK12 cyclin dependent kinase 12 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar NCBI chr 9:22,900,170...22,979,353
Ensembl chr 9:22,917,979...22,979,019 		JBrowse link
G CDK4 cyclin dependent kinase 4 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:5377176 PMID:7652577 PMID:8528263 PMID:8968104 PMID:9228064 More... NCBI chr10:1,812,864...1,815,815
Ensembl chr10:1,812,886...1,815,789 		JBrowse link
G CDK6 cyclin dependent kinase 6 ISO protein:increased expression:lung RGD PMID:10574260 RGD:13464325 NCBI chr14:18,178,352...18,413,869
Ensembl chr14:18,188,429...18,419,869 		JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:7780957 PMID:8521414 PMID:9324288 PMID:10491434 PMID:16234564 More... NCBI chr11:41,223,316...41,226,056
Ensembl chr11:41,223,315...41,264,379 		JBrowse link
G CHD4 chromodomain helicase DNA binding protein 4 ameliorates
susceptibility		 ISO mRNA:increased expression:lung (human)
human cells in a mouse model
DNA:missense mutation:CDS:p.D140E (rs7479004) (human)		 RGD PMID:28486105 PMID:29667179 PMID:32228507 RGD:151660359 RGD:153323299 RGD:153323307 NCBI chr27:38,411,009...38,440,367
Ensembl chr27:38,411,075...38,439,958 		JBrowse link
G CHRNA3 cholinergic receptor nicotinic alpha 3 subunit susceptibility ISO associated with smoking; DNA:SNP: :rs1051730(human)
ClinVar Annotator: match by term: Lung adenocarcinoma
DNA:SNP: :rs8042374(human)		 RGD
ClinVar		 PMID:20554942 PMID:24686516 PMID:27993330 RGD:150527848 RGD:151347530 NCBI chr13:38,330,287...38,343,142
Ensembl chr13:38,328,814...38,346,246 		JBrowse link
G CHRNA5 cholinergic receptor nicotinic alpha 5 subunit susceptibility
disease_progression		 ISO DNA:SNP: :rs503464(human)
associated with smoking; DNA:SNPs: :rs2036527, rs684513, rs667282(human)
DNA:SNP:cds: p.D398N(human)
ClinVar Annotator: match by term: Lung adenocarcinoma		 RGD
ClinVar		 PMID:19577767 PMID:20554942 PMID:23314339 PMID:27993330 RGD:150524359 RGD:150527848 RGD:150527849 NCBI chr13:38,343,966...38,355,534
Ensembl chr13:38,346,104...38,355,468 		JBrowse link
G CHRNB4 cholinergic receptor nicotinic beta 4 subunit ISO mRNA:increased expression:lung
DNA:hypomethylation:promoter:		 RGD PMID:20124469 PMID:22945651 RGD:150527851 RGD:151361154 NCBI chr13:38,312,537...38,327,242
Ensembl chr13:38,312,173...38,328,341 		JBrowse link
G CLPTM1L CLPTM1 like susceptibility
no_association
ameliorates		 ISO CTD Direct Evidence: marker/mechanism
DNA:SNP:: rs31490(human)
DNA:SNP::rs401681(human)
DNA:SNP:: rs4975616(human)
mRNA:increased expression:lung
DNA:SNP: :rs401681(human)
DNA:SNP::rs77518573(human)		 CTD
RGD		 PMID:19955392 PMID:22675468 PMID:23738012 PMID:23908149 PMID:24366883 More... RGD:150530483 RGD:150530485 RGD:150530498 RGD:150530499 RGD:150530502 RGD:150530635 RGD:150537098 NCBI chr34:11,263,274...11,277,666
Ensembl chr34:11,263,162...11,277,436 		JBrowse link
G CMTR2 cap methyltransferase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr 5:77,117,795...77,124,995
Ensembl chr 5:77,118,964...77,121,264 		JBrowse link
G COL10A1 collagen type X alpha 1 chain disease_progression ISO mRNA:increased expression:lung RGD PMID:33324550 RGD:150429752 NCBI chr12:71,803,372...71,810,049
Ensembl chr12:71,798,692...71,809,399 		JBrowse link
G CREBBP CREB binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr 6:37,410,201...37,536,688
Ensembl chr 6:37,409,930...37,534,176 		JBrowse link
G CSF1R colony stimulating factor 1 receptor ISO protein:increased expression:lung (human) RGD PMID:23702648 RGD:150524280 NCBI chr 4:58,980,699...59,010,683
Ensembl chr 4:58,980,788...59,010,510 		JBrowse link
G CSRP3 cysteine and glycine rich protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr21:41,300,277...41,318,788
Ensembl chr21:41,300,425...41,318,738 		JBrowse link
G CTNNB1 catenin beta 1 ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:9065402 PMID:9065403 PMID:9294210 PMID:9500465 PMID:9927029 More... NCBI chr23:10,559,722...10,572,933
Ensembl chr23:10,559,718...10,572,927 		JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 exacerbates ISO protein:increased expression:lung (human)
mRNA:increased expression:lung (human)		 RGD PMID:19716197 PMID:30103827 RGD:152023735 RGD:152177480 NCBI chr19:38,874,650...38,877,740
Ensembl chr19:38,874,145...38,877,740 		JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 ISO protein:increased expression:lung (human) RGD PMID:19358281 RGD:152177688 NCBI chr17:30,273,281...30,278,554
Ensembl chr17:30,272,749...30,278,554 		JBrowse link
G CYP24A1 cytochrome P450 family 24 subfamily A member 1 ameliorates ISO DNA:hypomethylation:promoter (human)
mRNA:decreased expression:lung (human)
human cell line in a mouse model		 RGD PMID:24736069 PMID:25519225 PMID:27793774 RGD:151361181 RGD:151665173 RGD:151665499 NCBI chr24:39,861,018...39,878,161
Ensembl chr24:39,862,355...39,878,216 		JBrowse link
G CYP2A13 cytochrome P450 family 2 subfamily A polypeptide 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18669584 NCBI chr 1:112,932,246...112,938,248
Ensembl chr 1:112,931,985...112,938,350 		JBrowse link
G DDR2 discoidin domain receptor tyrosine kinase 2 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr38:20,002,984...20,152,930
Ensembl chr38:20,008,057...20,152,275 		JBrowse link
G DLL4 delta like canonical Notch ligand 4 treatment ISO RGD PMID:33628824 RGD:155663482 NCBI chr30:8,059,463...8,068,742
Ensembl chr30:8,059,512...8,067,940 		JBrowse link
G DNMT3A DNA methyltransferase 3 alpha ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:21067377 PMID:21518476 PMID:22160010 PMID:22722925 PMID:22744846 More... NCBI chr17:19,489,524...19,563,074
Ensembl chr17:19,492,193...19,563,902 		JBrowse link
G DNMT3B DNA methyltransferase 3 beta susceptibility ISO DNA:SNPs,haplotype:promoter:-283T >C,-579G>T(human) RGD PMID:15528220 RGD:9589086 NCBI chr24:22,096,386...22,123,378
Ensembl chr24:22,096,349...22,122,900 		JBrowse link
G DOK1 docking protein 1 disease_progression ISO RGD PMID:20139980 RGD:152177521 NCBI chr17:48,588,579...48,591,523
Ensembl chr17:48,589,023...48,591,721 		JBrowse link
G DOK2 docking protein 2 disease_progression
exacerbates		 ISO mRNA:decreased expression:lung (human) RGD PMID:20139980 PMID:24255704 PMID:30475228 RGD:152177492 RGD:152177493 RGD:152177521 NCBI chr25:35,328,767...35,338,712
Ensembl chr25:35,334,176...35,339,175 		JBrowse link
G DOK3 docking protein 3 disease_progression ISO RGD PMID:20139980 RGD:152177521 NCBI chr 4:35,860,006...35,873,539
Ensembl chr 4:35,861,765...35,867,450 		JBrowse link
G DOT1L DOT1 like histone lysine methyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr20:56,805,030...56,868,771
Ensembl chr20:56,803,242...56,852,539 		JBrowse link
G E2F3 E2F transcription factor 3 ISO RGD PMID:16938365 RGD:13464341 NCBI chr35:19,012,646...19,086,674
Ensembl chr35:19,012,324...19,083,634 		JBrowse link
G EEF2 eukaryotic translation elongation factor 2 exacerbates ISO protein:increased expression:lung (human) RGD PMID:21554491 RGD:153298904 NCBI chr20:55,577,413...55,586,422
Ensembl chr20:55,522,213...55,586,126 		JBrowse link
G EEF2K eukaryotic elongation factor 2 kinase ameliorates ISO Human cells in mouse model RGD PMID:30522114 RGD:153298964 NCBI chr 6:23,368,296...23,433,853
Ensembl chr 6:23,371,546...23,433,929 		JBrowse link
G EGF epidermal growth factor ISO DNA:polymorphism: :p.A61G (human) RGD PMID:26625757 RGD:11538684 NCBI chr32:30,073,541...30,166,904
Ensembl chr32:30,073,950...30,166,295 		JBrowse link
G EGFR epidermal growth factor receptor disease_progression ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Adenocarcinoma of lung, somatic | ClinVar Annotator: match by term: Lung adenocarcinoma RGD
ClinVar		 PMID:2302402 PMID:11423618 PMID:15118073 PMID:15118125 PMID:15272417 More... RGD:126790475 NCBI chr18:5,983,669...6,044,092
Ensembl chr18:5,982,770...6,042,631 		JBrowse link
G EHMT2 euchromatic histone lysine methyltransferase 2 disease_progression ISO RGD PMID:20940408 RGD:9589170 NCBI chr12:1,341,202...1,354,602
Ensembl chr12:1,341,191...1,354,584 		JBrowse link
G EIF2B1 eukaryotic translation initiation factor 2B subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr26:6,011,280...6,022,562
Ensembl chr26:6,011,301...6,022,518 		JBrowse link
G EIF2B4 eukaryotic translation initiation factor 2B subunit delta ISO CTD Direct Evidence: marker/mechanism CTD PMID:24366584 NCBI chr17:21,321,329...21,326,357
Ensembl chr17:21,321,349...21,326,244 		JBrowse link
G EIF2B5 eukaryotic translation initiation factor 2B subunit epsilon ISO CTD Direct Evidence: marker/mechanism CTD PMID:24366584 NCBI chr34:17,038,163...17,047,390
Ensembl chr34:17,038,203...17,046,928 		JBrowse link
G EIF3E eukaryotic translation initiation factor 3 subunit E ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr13:8,834,724...8,887,818
Ensembl chr13:8,834,821...8,887,760 		JBrowse link
G EML4 EMAP like 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22980554 PMID:22999080 NCBI chr17:33,774,478...33,935,478
Ensembl chr17:33,774,140...33,934,147 		JBrowse link
G EMX2 empty spiracles homeobox 2 exacerbates ISO mRNA,protein:decreased expression:lung (human) RGD PMID:21726823 RGD:153323303 NCBI chr28:28,002,966...28,009,955
Ensembl chr28:28,003,710...28,009,035 		JBrowse link
G ENO1 enolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 PMID:27602772 NCBI chr 5:62,300,805...62,314,508
Ensembl chr 5:62,300,808...62,304,093 		JBrowse link
G EP300 E1A binding protein p300 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr10:24,076,538...24,156,708
Ensembl chr10:24,077,971...24,156,396 		JBrowse link
G EPHA5 EPH receptor A5 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:16140923 NCBI chr13:56,054,247...56,402,583
Ensembl chr13:56,058,800...56,383,301 		JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 disease_progression ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma RGD
ClinVar		 PMID:15457249 PMID:15753357 PMID:16638863 PMID:18334834 PMID:22325357 More... RGD:126790475 NCBI chr 9:22,760,373...22,785,367
Ensembl chr 9:22,759,256...22,785,294 		JBrowse link
G ERBB3 erb-b2 receptor tyrosine kinase 3 disease_progression ISO RGD PMID:26824984 RGD:126790475 NCBI chr10:406,856...424,746
Ensembl chr10:406,633...424,264 		JBrowse link
G ERBB4 erb-b2 receptor tyrosine kinase 4 disease_progression ISO RGD PMID:26824984 RGD:126790475 NCBI chr37:19,029,647...20,134,576
Ensembl chr37:19,037,217...20,134,426 		JBrowse link
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:21327329 NCBI chr 1:110,130,353...110,146,660
Ensembl chr 1:110,130,481...110,146,602 		JBrowse link
G ERCC6 ERCC excision repair 6, chromatin remodeling factor ISO mRNA, protein:increased expression:lung (human) RGD PMID:31615563 RGD:155260344 NCBI chr28:1,358,383...1,432,276
Ensembl chr28:1,361,107...1,427,162 		JBrowse link
G ERCC6L ERCC excision repair 6 like, spindle assembly checkpoint helicase exacerbates ISO mRNA:increased expression:lung (human) RGD PMID:35150321 RGD:155260359 NCBI chr  X:56,239,820...56,260,384
Ensembl chr  X:56,239,850...56,260,759 		JBrowse link
G ERGIC3 ERGIC and golgi 3 ameliorates
disease_progression		 ISO mRNA,protein:increased expression:lung (human) RGD PMID:23374247 PMID:27588471 RGD:151708716 RGD:153323314 NCBI chr24:24,494,494...24,508,114
Ensembl chr24:24,494,524...24,508,113 		JBrowse link
G ERP29 endoplasmic reticulum protein 29 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr26:9,608,352...9,616,711
Ensembl chr26:9,608,399...9,616,338 		JBrowse link
G ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2 ameliorates ISO RGD PMID:33573689 RGD:155791670 NCBI chr25:29,785,641...29,812,536
Ensembl chr25:29,787,132...29,811,112 		JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit disease_progression ISO RGD PMID:24097870 RGD:126781716 NCBI chr16:1,926,443...1,991,995
Ensembl chr16:1,925,956...1,991,838 		JBrowse link
G FAS Fas cell surface death receptor ISO mRNA:decreased expression:lung (human) RGD PMID:29254206 RGD:151665107 NCBI chr26:38,738,811...38,763,298
Ensembl chr26:38,737,611...38,763,321 		JBrowse link
G FASN fatty acid synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 9:233,105...249,573
Ensembl chr 9:232,963...249,092 		JBrowse link
G FBL fibrillarin ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:113,632,899...113,643,805
Ensembl chr 1:113,632,929...113,643,748 		JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 ISO ClinVar Annotator: match by term: Adenocarcinoma of lung ClinVar PMID:26619011 NCBI chr15:50,187,579...50,417,188
Ensembl chr15:50,189,240...50,417,195 		JBrowse link
G FES FES proto-oncogene, tyrosine kinase treatment ISO human cells in a mouse model RGD PMID:31573955 RGD:153323295 NCBI chr 3:53,346,975...53,356,547
Ensembl chr 3:53,347,012...53,356,516 		JBrowse link
G FGF10 fibroblast growth factor 10 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr 4:65,851,130...65,930,944
Ensembl chr 4:65,851,069...65,928,192 		JBrowse link
G FGF18 fibroblast growth factor 18 ISO mRNA:decreased expression:lung (human) RGD PMID:19296538 RGD:150429981 NCBI chr 4:40,714,891...40,748,892
Ensembl chr 4:40,715,060...40,748,518 		JBrowse link
G FGF9 fibroblast growth factor 9 disease_progression ISO protein:increased expression:lung (human)
mRNA:decreased expression:lung (human)		 RGD PMID:19296538 PMID:19358281 PMID:20464547 RGD:150429981 RGD:152177688 RGD:152975620 NCBI chr25:16,630,321...16,665,935
Ensembl chr25:16,632,812...16,663,550 		JBrowse link
G FGFR2 fibroblast growth factor receptor 2 ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:17525745 PMID:18552176 PMID:22238366 PMID:23002168 PMID:23908597 More... NCBI chr28:31,303,882...31,411,015
Ensembl chr28:31,303,894...31,411,621 		JBrowse link
G FGFR3 fibroblast growth factor receptor 3 ISO ClinVar Annotator: match by term: Adenocarcinoma of lung ClinVar PMID:1908846 PMID:7773297 PMID:8640234 PMID:8858131 PMID:9438390 More... NCBI chr 3:62,309,128...62,318,932
Ensembl chr 3:62,303,756...62,323,896 		JBrowse link
G FGFR4 fibroblast growth factor receptor 4 disease_progression
exacerbates		 ISO DNA:SNP:exon 9: p.G388R (human)
DNA:SNP:exon 9: p.G388R (rs351855)(human)
human cells in mouse model		 RGD PMID:16061909 PMID:19296538 PMID:29402970 RGD:150429976 RGD:150429981 RGD:150429984 NCBI chr 4:36,243,689...36,254,636
Ensembl chr 4:36,244,220...36,252,035 		JBrowse link
G FKBP11 FKBP prolyl isomerase 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr27:5,636,643...5,639,521
Ensembl chr27:5,636,627...5,639,509 		JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr25:11,231,958...11,410,379
Ensembl chr25:11,231,737...11,407,621 		JBrowse link
G FOXA1 forkhead box A1 ISO mRNA:increased expression:lung
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:12234996 PMID:29072684 PMID:34254728 RGD:151665758 RGD:151665822 NCBI chr 8:16,072,629...16,083,105
Ensembl chr 8:16,079,140...16,083,807 		JBrowse link
G FOXO3 forkhead box O3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19380174 NCBI chr12:65,552,455...65,673,467
Ensembl chr12:65,552,310...65,670,198 		JBrowse link
G FOXP1 forkhead box P1 ISO mRNA:decreased expression:lung (rat) RGD PMID:16023287 RGD:11561933 NCBI chr20:20,438,631...21,020,516
Ensembl chr20:20,788,433...21,016,397 		JBrowse link
G FOXP2 forkhead box P2 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr14:53,311,214...53,864,056
Ensembl chr14:53,312,045...53,862,655 		JBrowse link
G FOXP4 forkhead box P4 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr12:10,239,402...10,292,892
Ensembl chr12:10,258,166...10,291,125 		JBrowse link
G FPR formyl peptide receptor ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr 1:105,343,096...105,353,563
Ensembl chr 1:105,344,463...105,372,070 		JBrowse link
G FRZB frizzled related protein severity ISO mRNA:decreased expression:lung (human) RGD PMID:27623992 RGD:32716395 NCBI chr36:25,884,557...25,907,436
Ensembl chr36:25,884,557...25,907,369 		JBrowse link
G FUBP1 far upstream element binding protein 1 ISO mRNA:decreased expression:lung (human) RGD PMID:32481602 RGD:151361197 NCBI chr 6:68,923,215...68,963,766 JBrowse link
G GAPDH glyceraldehyde-3-phosphate dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr27:38,468,889...38,472,653
Ensembl chr27:38,468,889...38,472,385 		JBrowse link
G GAR1 GAR1 ribonucleoprotein ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr32:29,995,710...30,004,545
Ensembl chr32:29,996,148...30,004,536 		JBrowse link
G GJB2 gap junction protein beta 2 ISO DNA, mRNA:hypermethylation, decreased expression:lung RGD PMID:16637067 RGD:11568669 NCBI chr25:17,952,851...17,958,289
Ensembl chr25:17,952,851...17,958,289 		JBrowse link
G GNAS GNAS complex locus ISO ClinVar Annotator: match by term: Adenocarcinoma of lung ClinVar PMID:1517386 PMID:1594625 PMID:1944469 PMID:2549426 PMID:3720010 More... NCBI chr24:43,643,409...43,658,641
Ensembl chr24:43,643,405...43,658,657 		JBrowse link
G GNG11 G protein subunit gamma 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24366584 NCBI chr14:19,426,916...19,431,232
Ensembl chr14:19,426,685...19,431,235 		JBrowse link
G GNPNAT1 glucosamine-phosphate N-acetyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 8:28,992,173...29,005,511
Ensembl chr 8:28,993,227...29,005,435 		JBrowse link
G GOLM1 golgi membrane protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:73,609,224...73,654,280
Ensembl chr 1:73,546,172...73,652,370 		JBrowse link
G GPI glucose-6-phosphate isomerase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:117,922,380...117,948,325
Ensembl chr 1:117,922,635...117,948,316 		JBrowse link
G GPX3 glutathione peroxidase 3 ISO mRNA:decreased expression:lung (human) RGD PMID:23374247 RGD:151708716 NCBI chr 4:58,200,671...58,209,010
Ensembl chr 4:58,200,672...58,209,010 		JBrowse link
G GRWD1 glutamate rich WD repeat containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:107,814,402...107,821,107
Ensembl chr 1:107,815,063...107,820,858 		JBrowse link
G H1-10 H1.10 linker histone ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr20:2,799,360...2,800,524 JBrowse link
G H2BC4 H2B clustered histone 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr35:24,062,068...24,066,934
Ensembl chr35:24,066,399...24,066,779 		JBrowse link
G HELLS helicase, lymphoid specific ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr28:8,660,866...8,705,570
Ensembl chr28:8,661,008...8,705,580 		JBrowse link
G HEYL hes related family bHLH transcription factor with YRPW motif like ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr15:3,242,738...3,257,275
Ensembl chr15:3,235,611...3,303,445 		JBrowse link
G HK1 hexokinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 4:20,396,761...20,516,889
Ensembl chr 4:20,421,526...20,518,211 		JBrowse link
G HK2 hexokinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr17:48,287,367...48,329,470
Ensembl chr17:48,289,272...48,348,663 		JBrowse link
G HMGB2 high mobility group box 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24366584 PMID:27602772 NCBI chr25:23,939,024...23,941,720
Ensembl chr25:23,939,027...23,941,606 		JBrowse link
G HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr27:1,013,459...1,020,083
Ensembl chr27:1,015,868...1,019,891 		JBrowse link
G HOXB7 homeobox B7 severity ISO protein:increased expression:lung epithelium (human) RGD PMID:22911672 RGD:10402176 NCBI chr 9:24,870,037...24,874,517
Ensembl chr 9:24,870,612...24,873,453 		JBrowse link
G HRAS HRas proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma
ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Adenocarcinoma of lung, somatic		 ClinVar PMID:1904555 PMID:3510078 PMID:11150980 PMID:12835555 PMID:16155195 More... NCBI chr18:25,642,844...25,644,717
Ensembl chr18:25,642,844...25,644,717 		JBrowse link
G HSD17B10 hydroxysteroid 17-beta dehydrogenase 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr  X:45,165,272...45,167,683
Ensembl chr  X:45,165,272...45,167,574 		JBrowse link
G HSP90B1 heat shock protein 90 beta family member 1 ISO mRNA:increased expression:lung (human) RGD PMID:23374247 RGD:151708716 NCBI chr15:42,456,793...42,474,122
Ensembl chr15:42,456,764...42,579,311 		JBrowse link
G HSPB1 heat shock protein family B (small) member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr 6:7,487,164...7,488,576
Ensembl chr 6:7,487,250...7,488,576 		JBrowse link
G HTR4 5-hydroxytryptamine receptor 4 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr 4:60,224,534...60,359,244
Ensembl chr 4:60,185,056...60,353,439 		JBrowse link
G HTRA1 HtrA serine peptidase 1 disease_progression ISO human cells in mouse model RGD PMID:24356998 RGD:152975621 NCBI chr28:32,133,779...32,157,835
Ensembl chr28:32,132,547...32,157,409 		JBrowse link
G IDH1 isocitrate dehydrogenase (NADP(+)) 1 disease_progression ISO protein:increased expression:blood plasma (human)
ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma
mRNA:increased expression:lung (human)		 RGD
ClinVar		 PMID:18772396 PMID:19657110 PMID:19798509 PMID:19818334 PMID:20946881 More... RGD:149735539 RGD:149735540 NCBI chr37:16,512,027...16,531,269
Ensembl chr37:16,512,770...16,531,219 		JBrowse link
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 severity ISO protein:increased expression:lung (human)
protein:increased expression:blood serum (human)		 RGD PMID:29465809 PMID:30128035 RGD:149735564 RGD:149735567 NCBI chr 3:53,070,462...53,077,566
Ensembl chr 3:53,070,695...53,087,496 		JBrowse link
G IGF2R insulin like growth factor 2 receptor ISO mRNA:deletions: :c.3698_4902del, c.3366_4902del, c.3817_4697del (rat) RGD PMID:12503077 RGD:1298968 NCBI chr 1:49,161,551...49,262,260
Ensembl chr 1:49,161,444...49,262,277 		JBrowse link
G IKZF1 IKAROS family zinc finger 1 exacerbates
ameliorates		 ISO protein:increased expression:lung (human)
mRNA:increased expression:lung (human)		 RGD PMID:32787735 PMID:33738286 RGD:150540324 RGD:151347632 NCBI chr18:1,661,851...1,750,987
Ensembl chr18:1,661,690...1,770,768 		JBrowse link
G IL1R2 interleukin 1 receptor type 2 disease_progression
severity		 ISO mRNA:altered expression:lung (human)
mRNA:increased expression:lung (human)		 RGD PMID:29942094 PMID:31921619 RGD:152998982 RGD:152998998 NCBI chr10:40,967,532...41,003,659
Ensembl chr10:40,896,669...41,034,113 		JBrowse link
G IMPDH2 inosine monophosphate dehydrogenase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr20:40,136,106...40,140,983
Ensembl chr20:40,136,154...40,140,972 		JBrowse link
G IPO4 importin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 8:4,171,525...4,180,666
Ensembl chr 8:4,171,527...4,181,151 		JBrowse link
G IPO5 importin 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr22:48,126,053...48,182,897
Ensembl chr22:48,136,242...48,180,495 		JBrowse link
G IQSEC1 IQ motif and Sec7 domain ArfGEF 1 disease_progression ISO RGD PMID:24902879 RGD:153350085 NCBI chr20:3,241,058...3,403,394
Ensembl chr20:3,241,052...3,522,859 		JBrowse link
G IRAK3 interleukin 1 receptor associated kinase 3 ISO mRNA:increased expression:lung (human) RGD PMID:21278795 RGD:36049796 NCBI chr10:8,683,541...8,730,757
Ensembl chr10:8,684,242...8,729,268 		JBrowse link
G IREB2 iron responsive element binding protein 2 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr13:38,398,445...38,441,128
Ensembl chr13:38,400,591...38,441,015 		JBrowse link
G JAK2 Janus kinase 2 treatment ISO human cells in mouse model RGD PMID:27025877 RGD:11574134 NCBI chr 1:93,321,055...93,438,898
Ensembl chr 1:93,142,635...93,435,997 		JBrowse link
G JUNB JunB proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:24366584 NCBI chr20:49,358,904...49,360,746
Ensembl chr20:49,359,399...49,360,442 		JBrowse link
G KCNJ4 potassium inwardly rectifying channel subfamily J member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30512237 NCBI chr10:26,321,274...26,348,978
Ensembl chr10:26,347,140...26,348,486 		JBrowse link
G KLF5 KLF transcription factor 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr22:27,163,179...27,185,241
Ensembl chr22:27,162,397...27,200,871 		JBrowse link
G KMT2C lysine methyltransferase 2C disease_progression
onset		 ISO RGD PMID:30821106 PMID:32867667 RGD:151356760 RGD:151356761 NCBI chr16:15,962,045...16,117,601
Ensembl chr16:15,963,901...16,158,408 		JBrowse link
G KPNA2 karyopherin subunit alpha 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 9:12,546,912...12,556,163 JBrowse link
G KRAS KRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Adenocarcinoma of lung ClinVar PMID:2278970 PMID:3122217 PMID:6320174 PMID:11745231 PMID:12460918 More... NCBI chr27:22,261,753...22,296,704
Ensembl chr27:22,257,941...22,293,369 		JBrowse link
G LDHA lactate dehydrogenase A ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr21:40,829,844...40,840,947 JBrowse link
G LECT2 leukocyte cell derived chemotaxin 2 ameliorates ISO human cells in mouse model RGD PMID:30453282 RGD:153323337 NCBI chr11:23,864,062...23,873,720
Ensembl chr11:23,864,064...23,886,226 		JBrowse link
G LMNA lamin A/C ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr 7:41,702,491...41,719,870
Ensembl chr 7:41,508,450...41,746,931 		JBrowse link
G LMNB1 lamin B1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr11:15,996,627...16,052,719
Ensembl chr11:15,930,436...16,052,127 		JBrowse link
G LOC100688091 small nucleolar RNA SNORD22 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr18:53,841,419...53,850,465 JBrowse link
G LOC102151342 ATP synthase subunit d, mitochondrial-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr 7:66,856,651...66,857,162 JBrowse link
G LOC102155800 60S ribosomal protein L36a-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr17:52,628,292...52,628,713 JBrowse link
G LOC477072 serotransferrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr23:30,658,250...30,683,816
Ensembl chr23:30,595,704...30,683,845 		JBrowse link
G LOC487740 trifunctional purine biosynthetic protein adenosine-3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr31:29,032,399...29,063,706 JBrowse link
G LRP1B LDL receptor related protein 1B disease_progression ISO DNA:mutations:multiple: (human) RGD PMID:18948947 RGD:11064706 NCBI chr19:42,608,167...44,427,492
Ensembl chr19:42,609,684...44,427,262 		JBrowse link
G LRRC56 leucine rich repeat containing 56 ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:1904555 PMID:3510078 PMID:11150980 PMID:12835555 PMID:16155195 More... NCBI chr18:25,647,024...25,662,646
Ensembl chr18:25,647,882...25,664,220 		JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:18632602 PMID:21383288 PMID:22197931 PMID:22588879 PMID:23444215 More... NCBI chr30:30,683,192...30,760,479
Ensembl chr30:30,683,107...30,760,479 		JBrowse link
G MAP2K4 mitogen-activated protein kinase kinase 4 severity ISO RGD PMID:12231543 PMID:21896780 RGD:150429783 RGD:150429821 NCBI chr 5:36,142,610...36,243,673
Ensembl chr 5:36,118,388...36,241,296 		JBrowse link
G MAP2K7 mitogen-activated protein kinase kinase 7 exacerbates ISO human gene in a mouse model RGD PMID:34236045 RGD:155230828 NCBI chr20:52,594,450...52,604,236
Ensembl chr20:52,594,536...52,602,150 		JBrowse link
G MAP3K8 mitogen-activated protein kinase kinase kinase 8 exacerbates ISO RGD PMID:23533274 RGD:151356978 NCBI chr 2:16,717,845...16,740,816
Ensembl chr 2:16,720,596...16,740,515 		JBrowse link
G MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 exacerbates
ameliorates		 ISO mRNA, protein:increased expression:lung (human)
human cell line in a mouse model		 RGD PMID:22824148 PMID:28306189 PMID:33510968 RGD:151347677 RGD:151347678 RGD:151347681 NCBI chr10:41,088,020...41,276,801
Ensembl chr10:41,089,371...41,276,891 		JBrowse link
G MAPK14 mitogen-activated protein kinase 14 exacerbates ISO mRNA:increased expression:lung (human) RGD PMID:31969449 RGD:151665505 NCBI chr12:5,145,647...5,221,558
Ensembl chr12:5,146,037...5,220,603 		JBrowse link
G MCL1 MCL1 apoptosis regulator, BCL2 family member severity
treatment		 ISO mRNA:increased expression:lung (human)
human cells in mouse model		 RGD PMID:31200834 RGD:151356911 NCBI chr17:59,759,605...59,763,111
Ensembl chr17:59,759,605...59,763,111 		JBrowse link
G MEOX1 mesenchyme homeobox 1 ISO CTD Direct Evidence: therapeutic CTD PMID:34837450 NCBI chr 9:19,614,568...19,641,426
Ensembl chr 9:19,614,503...19,640,908 		JBrowse link
G MIR127 microRNA mir-127 treatment ISO Human cells in mouse model RGD PMID:27869168 RGD:152995353 NCBI chr 8:69,104,938...69,104,997
Ensembl chr 8:69,104,906...69,105,016 		JBrowse link
G MIR20A microRNA mir-20a ISO RGD PMID:26560875 RGD:11572141 NCBI chr22:42,478,462...42,478,520
Ensembl chr22:42,478,462...42,478,520 		JBrowse link
G MIR21 microRNA mir-21 disease_progression ISO RNA:increased expression:lung (human)
miRNA:increased expression:sputum (human)		 RGD PMID:27777637 PMID:29892003 RGD:152998892 RGD:152998954 NCBI chr 9:34,340,550...34,340,609
Ensembl chr 9:34,340,533...34,340,624 		JBrowse link
G MIR31 microRNA mir-31 disease_progression
severity		 ISO RNA:increased expression:lung (human) RGD PMID:23946296 PMID:26657862 PMID:27215092 PMID:29367106 RGD:11250998 RGD:11343268 RGD:152998944 RGD:152998945 NCBI chr11:40,904,438...40,904,496
Ensembl chr11:40,904,437...40,904,503 		JBrowse link
G MIR432 microRNA mir-432 disease_progression ISO human cells in mouse model
mRNA:decreased expression:lung (human)		 RGD PMID:26942465 RGD:152999419 NCBI chr 8:69,106,415...69,106,501
Ensembl chr 8:69,106,415...69,106,501 		JBrowse link
G MKI67 marker of proliferation Ki-67 disease_progression ISO protein:altered expression:lung (human) RGD PMID:26942465 RGD:152999419 NCBI chr28:36,920,679...36,939,336
Ensembl chr28:36,913,023...36,939,486 		JBrowse link
G MKI67IP MKI67 (FHA domain) interacting nucleolar phosphoprotein EXP CTD Direct Evidence: marker/mechanism CTD PMID:27602772
G MLH1 mutL homolog 1 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:15340264 PMID:17510385 PMID:18307539 PMID:19419416 PMID:22136435 More... NCBI chr23:6,889,108...6,938,117
Ensembl chr23:6,889,135...6,938,116 		JBrowse link
G MRE11 MRE11 homolog, double strand break repair nuclease ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr21:6,448,909...6,528,185
Ensembl chr21:6,449,822...6,527,119 		JBrowse link
G MRPL12 mitochondrial ribosomal protein L12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 9:493,536...498,154 JBrowse link
G MRPS5 mitochondrial ribosomal protein S5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr17:34,926,674...34,952,665
Ensembl chr17:34,926,743...34,952,473 		JBrowse link
G MS4A1 membrane spanning 4-domains A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22514692 NCBI chr21:50,722,142...50,734,934
Ensembl chr21:50,722,041...50,733,704 		JBrowse link
G MSH2 mutS homolog 2 no_association ISO DNA:polymorphisms:promoter, intron:-118T>C, IVS1+9G>C (human)
DNA:polymorphisms:introns:IVS10+12A>G, IVS12-6T>C (human)		 RGD PMID:16614121 RGD:11065547 NCBI chr10:49,517,448...49,594,001
Ensembl chr10:49,517,369...49,594,210 		JBrowse link
G MSH3 mutS homolog 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21327329 NCBI chr 3:26,335,788...26,520,633
Ensembl chr 3:26,336,403...26,518,521 		JBrowse link
G MSH6 mutS homolog 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21327329 NCBI chr10:49,825,330...49,838,036
Ensembl chr10:49,803,898...49,838,028 		JBrowse link
G MUC1 mucin 1, cell surface associated ISO mRNA:increased expression:lung RGD PMID:8694545 RGD:5131260 NCBI chr 7:42,338,939...42,344,690
Ensembl chr 7:42,340,375...42,344,690 		JBrowse link
G MUC4 mucin 4, cell surface associated disease_progression ISO protein:increased expression:trachea RGD PMID:17126950 RGD:5131208 NCBI chr33:29,061,372...29,084,938
Ensembl chr33:29,063,096...29,111,802 		JBrowse link
G MUC5AC mucin 5AC, oligomeric mucus/gel-forming ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr18:45,471,232...45,498,961 JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:25157968 PMID:26619011 NCBI chr13:25,200,772...25,205,309
Ensembl chr13:25,200,577...25,205,309 		JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor treatment
ameliorates		 ISO mouse cell line in a mouse model RGD PMID:30712876 PMID:32140881 RGD:150520172 RGD:150540309 NCBI chr23:7,901,578...7,905,274
Ensembl chr23:7,901,250...7,904,534 		JBrowse link
G NAA10 N-alpha-acetyltransferase 10, NatA catalytic subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr  X:121,777,658...121,782,097
Ensembl chr  X:121,727,573...121,788,860 		JBrowse link
G NCAPG non-SMC condensin I complex subunit G ISO CTD Direct Evidence: marker/mechanism CTD PMID:34419073 NCBI chr 3:91,279,800...91,322,679
Ensembl chr 3:91,281,077...91,322,803 		JBrowse link
G NCL nucleolin ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr25:43,330,524...43,384,909
Ensembl chr25:43,330,799...43,384,258 		JBrowse link
G NECAB3 N-terminal EF-hand calcium binding protein 3 ISO mRNA:increased expression:lung RGD PMID:26695082 RGD:13464334 NCBI chr24:22,895,149...22,904,689
Ensembl chr24:22,878,402...22,904,656 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:26619011 PMID:29018201 NCBI chr36:20,989,205...21,087,044
Ensembl chr36:20,989,360...21,012,524 		JBrowse link
G NKX2-1 NK2 homeobox 1 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330
G NLRP3 NLR family pyrin domain containing 3 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr 8:251,776...313,290
Ensembl chr 8:253,407...313,059 		JBrowse link
G NOP56 NOP56 ribonucleoprotein ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr24:18,561,407...18,566,770
Ensembl chr24:18,561,408...18,566,719 		JBrowse link
G NOP58 NOP58 ribonucleoprotein ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr37:11,255,562...11,287,325
Ensembl chr37:11,255,589...11,287,279 		JBrowse link
G NOTCH1 notch receptor 1 treatment ISO RGD PMID:33628824 RGD:155663482 NCBI chr 9:48,975,972...49,018,985
Ensembl chr 9:48,974,757...49,017,277 		JBrowse link
G NPM1 nucleophosmin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 4:40,756,464...40,770,174
Ensembl chr 4:40,756,465...40,770,175 		JBrowse link
G NPM3 nucleophosmin/nucleoplasmin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr28:14,373,446...14,375,624
Ensembl chr28:14,373,452...14,404,541 		JBrowse link
G NRAS NRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Adenocarcinoma of lung ClinVar PMID:1654209 PMID:2278970 PMID:2674680 PMID:3122217 PMID:6587382 More... NCBI chr17:52,411,733...52,418,788
Ensembl chr17:52,411,733...52,418,788 		JBrowse link
G NUDT21 nudix hydrolase 21 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 2:59,736,739...59,751,967
Ensembl chr 2:59,736,186...59,751,704 		JBrowse link
G NUF2 NUF2 component of NDC80 kinetochore complex disease_progression ISO RGD PMID:32226507 RGD:28912743 NCBI chr38:19,574,122...19,599,821
Ensembl chr38:19,574,125...19,599,064 		JBrowse link
G OGG1 8-oxoguanine DNA glycosylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23951099 NCBI chr20:8,486,150...8,491,448
Ensembl chr20:8,480,005...8,491,264 		JBrowse link
G PACRG parkin coregulated ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:12719539 NCBI chr 1:51,202,146...51,717,076
Ensembl chr 1:51,202,164...51,717,070 		JBrowse link
G PCBD1 pterin-4 alpha-carbinolamine dehydratase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 4:21,719,863...21,723,493
Ensembl chr 4:21,719,863...21,721,574 		JBrowse link
G PIGN phosphatidylinositol glycan anchor biosynthesis class N ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:14,684,026...14,791,221
Ensembl chr 1:14,685,694...14,805,691 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 More... NCBI chr34:12,600,140...12,681,905
Ensembl chr34:12,600,233...12,675,910 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 ISO mRNA:decreased expression:lung RGD PMID:26695082 RGD:13464334 NCBI chr 2:53,447,802...53,527,563
Ensembl chr 2:53,448,286...53,524,970 		JBrowse link
G PITX2 paired like homeodomain 2 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr32:30,710,161...30,730,162
Ensembl chr32:30,710,685...30,730,273 		JBrowse link
G PLCG1 phospholipase C gamma 1 exacerbates ISO protein:decreased expression:lung (human) RGD PMID:33077911 RGD:151356960 NCBI chr24:29,198,536...29,213,899
Ensembl chr24:29,198,556...29,214,714 		JBrowse link
G PLOD2 procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 disease_progression ISO RGD PMID:29072684 RGD:151665822 NCBI chr23:41,290,183...41,382,917
Ensembl chr23:41,290,567...41,382,807 		JBrowse link
G POLD1 DNA polymerase delta 1, catalytic subunit exacerbates ISO protein:increased expression:lung (human) RGD PMID:33442399 RGD:153323317 NCBI chr 1:106,302,583...106,331,353
Ensembl chr 1:106,302,574...106,331,385 		JBrowse link
G POLR1D RNA polymerase I and III subunit D ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr25:11,997,020...11,998,742 JBrowse link
G PPAN peter pan homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr20:50,949,138...50,952,843
Ensembl chr20:50,949,138...50,952,843 		JBrowse link
G PPP2R1A protein phosphatase 2 scaffold subunit Aalpha ISO ClinVar Annotator: match by term: Adenocarcinoma of lung ClinVar PMID:25741868 PMID:26168268 PMID:26619011 PMID:28492532 PMID:31687265 More... NCBI chr 1:104,974,059...105,013,745
Ensembl chr 1:104,974,072...105,013,663 		JBrowse link
G PPP3CA protein phosphatase 3 catalytic subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr32:22,688,141...22,996,693
Ensembl chr32:22,688,143...22,996,688 		JBrowse link
G PRAME PRAME nuclear receptor transcriptional regulator ISO mRNA:decreased expression:lung (human) RGD PMID:27241212 RGD:11535020 NCBI chr26:27,124,901...27,137,772
Ensembl chr26:27,124,902...27,136,112 		JBrowse link
G PRDM1 PR/SET domain 1 exacerbates ISO RGD PMID:28378641 RGD:150530469 NCBI chr12:63,454,242...63,495,278
Ensembl chr12:63,470,974...63,495,579 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:12719539 NCBI chr 1:49,886,887...51,201,930
Ensembl chr 1:49,889,005...51,201,764 		JBrowse link
G PSAT1 phosphoserine aminotransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:80,376,469...80,408,177
Ensembl chr 1:80,377,115...80,408,162 		JBrowse link
G PTCH1 patched 1 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 PMID:28492532 NCBI chr 1:71,246,750...71,309,036
Ensembl chr 1:71,238,195...71,305,662 		JBrowse link
G PTEN phosphatase and tensin homolog ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr26:37,853,148...37,913,176
Ensembl chr26:37,835,661...37,913,176 		JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 ISO ClinVar Annotator: match by term: Adenocarcinoma of lung ClinVar PMID:26619011 PMID:26822237 NCBI chr26:9,989,218...10,072,245
Ensembl chr26:9,989,425...10,067,481 		JBrowse link
G PTPN13 protein tyrosine phosphatase non-receptor type 13 susceptibility
exacerbates		 ISO DNA:missense mutations:cds:p.I1522M, p.Y2081D (human)
mRNA,protein:decreased expression:lung		 RGD PMID:19672627 PMID:22245727 PMID:33536603 RGD:152176663 RGD:152176665 RGD:152975626 NCBI chr32:10,125,447...10,328,764
Ensembl chr32:10,125,441...10,328,757 		JBrowse link
G PTPRB protein tyrosine phosphatase receptor type B disease_progression ISO mRNA:decreased expression:lung (human)
mRNA:altered expression:lung (human)		 RGD PMID:7981622 PMID:29254206 RGD:151665107 RGD:151665112 NCBI chr10:12,267,891...12,384,522
Ensembl chr10:12,241,716...12,384,435 		JBrowse link
G PTPRJ protein tyrosine phosphatase receptor type J susceptibility ISO DNA:missense mutations:cds:p.R326Q, p.Q276P (human) RGD PMID:19672627 RGD:152176665 NCBI chr18:41,586,262...41,635,386
Ensembl chr18:41,586,112...41,635,308 		JBrowse link
G RAC1 Rac family small GTPase 1 exacerbates
ameliorates		 ISO mRNA:increased expression:lung (human) RGD PMID:31779616 PMID:32366477 RGD:152998910 RGD:153345550 NCBI chr 6:11,726,259...11,758,532
Ensembl chr 6:11,655,494...11,757,216 		JBrowse link
G RAF1 Raf-1 proto-oncogene, serine/threonine kinase ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:1760348 PMID:8601312 PMID:10064593 PMID:12077328 PMID:17603482 More... NCBI chr20:5,892,839...5,972,672
Ensembl chr20:5,892,834...5,972,090 		JBrowse link
G RANGRF RAN guanine nucleotide release factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 5:33,084,355...33,085,810
Ensembl chr 5:33,084,397...33,085,812 		JBrowse link
G RARB retinoic acid receptor beta ISO DNA:hypomethylation:lung RGD PMID:26695082 RGD:13464334 NCBI chr23:18,207,253...18,931,128
Ensembl chr23:18,207,760...18,482,652 		JBrowse link
G RASA1 RAS p21 protein activator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr 3:21,068,182...21,177,288
Ensembl chr 3:21,054,930...21,176,757 		JBrowse link
G RB1 RB transcriptional corepressor 1 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr22:3,061,621...3,204,625
Ensembl chr22:3,063,239...3,257,726 		JBrowse link
G RBM10 RNA binding motif protein 10 ISO mRNA, protein:decreased expression:lung
DNA:missense mutations, protein-truncating variants: :multiple		 RGD PMID:22980975 PMID:29085465 PMID:30955253 RGD:11097386 RGD:151356983 RGD:151356984 NCBI chr  X:40,746,959...40,776,764
Ensembl chr  X:40,747,178...40,776,742 		JBrowse link
G RCL1 RNA terminal phosphate cyclase like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:93,144,164...93,204,233
Ensembl chr 1:93,142,635...93,435,997 		JBrowse link
G RFC4 replication factor C subunit 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr34:19,361,024...19,377,289
Ensembl chr34:19,361,044...19,377,294 		JBrowse link
G RHOA ras homolog family member A ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:26619011 NCBI chr20:39,824,552...39,888,089
Ensembl chr20:39,824,575...39,887,215 		JBrowse link
G RIN3 Ras and Rab interactor 3 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr 8:1,733,051...1,804,138
Ensembl chr 8:1,700,161...1,803,950 		JBrowse link
G RNASEH2A ribonuclease H2 subunit A ISO CTD Direct Evidence: marker/mechanism CTD PMID:34254728 NCBI chr20:49,345,258...49,352,944
Ensembl chr20:49,345,266...49,355,167 		JBrowse link
G RNF43 ring finger protein 43 severity ISO human cells in a mouse model RGD PMID:31286874 RGD:151361222 NCBI chr 9:32,996,668...33,061,781
Ensembl chr 9:32,997,937...33,060,313 		JBrowse link
G ROS1 ROS proto-oncogene 1, receptor tyrosine kinase ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:23724914 PMID:27993330 NCBI chr 1:57,555,278...57,677,541
Ensembl chr 1:57,555,989...57,677,761 		JBrowse link
G RPL10A ribosomal protein L10a ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr12:4,601,760...4,604,142
Ensembl chr12:4,601,766...4,604,220 		JBrowse link
G RPL13A ribosomal protein L13a ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:107,010,190...107,014,267
Ensembl chr 1:107,010,190...107,014,267 		JBrowse link
G RPL27A ribosomal protein L27a ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr21:32,099,792...32,102,761
Ensembl chr21:32,099,792...32,102,754 		JBrowse link
G RPSA ribosomal protein SA ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr23:9,070,953...9,077,058
Ensembl chr23:9,070,953...9,077,057 		JBrowse link
G RRM1 ribonucleotide reductase catalytic subunit M1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr21:26,595,838...26,631,476
Ensembl chr21:26,595,914...26,631,135 		JBrowse link
G RRM2 ribonucleotide reductase regulatory subunit M2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr17:7,106,515...7,113,868
Ensembl chr17:7,104,961...7,122,939 		JBrowse link
G RRS1 ribosome biogenesis regulator 1 homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr29:16,016,134...16,018,046
Ensembl chr29:16,016,189...16,017,286 		JBrowse link
G RUNX1 RUNX family transcription factor 1 ISO RGD PMID:28926105 RGD:126779571 NCBI chr31:30,170,859...30,420,344
Ensembl chr31:30,170,605...30,420,839 		JBrowse link
G SATB1 SATB homeobox 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr23:24,614,198...24,692,254
Ensembl chr23:24,593,489...24,690,977 		JBrowse link
G SDC1 syndecan 1 ISO mRNA:increased expression:lung (human) RGD PMID:23374247 RGD:151708716 NCBI chr17:15,220,906...15,243,974
Ensembl chr17:15,222,094...15,243,890 		JBrowse link
G SERPINA3 serpin family A member 3 ISO protein:increased expression:cytoplasm RGD PMID:8620411 RGD:5147446 NCBI chr 8:63,588,188...63,596,955
Ensembl chr 8:63,587,891...63,596,954 		JBrowse link
G SETD2 SET domain containing 2, histone lysine methyltransferase exacerbates
ameliorates
severity		 ISO DNA:mutations:multiple (human)
human cells and genes in mouse model		 RGD PMID:27687306 PMID:28202515 PMID:33223508 PMID:33707235 RGD:126848875 RGD:150429633 RGD:150429648 RGD:150429649 NCBI chr20:41,675,539...41,800,697
Ensembl chr20:41,675,599...41,800,612 		JBrowse link
G SFN stratifin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr 2:73,268,289...73,269,663
Ensembl chr 2:73,268,791...73,269,537 		JBrowse link
G SFTPC surfactant protein C ISO CTD Direct Evidence: marker/mechanism CTD PMID:25851810 NCBI chr25:35,088,295...35,090,995
Ensembl chr25:35,088,279...35,091,457 		JBrowse link
G SFXN1 sideroflexin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 4:37,485,360...37,517,743
Ensembl chr 4:37,487,438...37,512,289 		JBrowse link
G SHMT1 serine hydroxymethyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 5:41,221,531...41,248,653
Ensembl chr 5:41,221,562...41,253,166 		JBrowse link
G SLC15A2 solute carrier family 15 member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr33:25,154,415...25,190,715
Ensembl chr33:25,154,448...25,189,929 		JBrowse link
G SLC19A1 solute carrier family 19 member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr31:38,958,332...38,971,091
Ensembl chr31:38,967,013...38,971,094 		JBrowse link
G SLC1A5 solute carrier family 1 member 5 disease_progression ISO RGD PMID:26279756 RGD:151361150 NCBI chr 1:109,150,205...109,161,375
Ensembl chr 1:109,150,205...109,161,141 		JBrowse link
G SLC22A18 solute carrier family 22 member 18 disease_progression ISO mRNA:increased expression:lung (human)
ClinVar Annotator: match by term: Lung adenocarcinoma		 RGD
ClinVar		 PMID:27993330 PMID:32726996 RGD:150557423 NCBI chr18:46,878,096...46,898,016
Ensembl chr18:46,878,030...46,898,006 		JBrowse link
G SLC3A2 solute carrier family 3 member 2 disease_progression ISO RGD PMID:19171406 RGD:151361151 NCBI chr18:53,810,468...53,819,021
Ensembl chr18:53,810,398...53,819,021 		JBrowse link
G SLC4A4 solute carrier family 4 member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr13:60,375,215...60,670,664
Ensembl chr13:60,328,136...60,666,728 		JBrowse link
G SLC4A7 solute carrier family 4 member 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr23:16,710,649...16,788,277
Ensembl chr23:16,710,701...16,785,541 		JBrowse link
G SLC7A5 solute carrier family 7 member 5 disease_progression ISO RGD PMID:19171406 PMID:26279756 RGD:151361150 RGD:151361151 NCBI chr 5:65,313,105...65,343,858
Ensembl chr 5:65,313,105...65,343,858 		JBrowse link
G SMAD4 SMAD family member 4 ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:6604412 PMID:8898652 PMID:9214508 PMID:9285566 PMID:9582123 More... NCBI chr 1:23,875,989...23,930,027
Ensembl chr 1:23,882,139...23,969,405 		JBrowse link
G SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr20:41,165,593...41,337,237
Ensembl chr20:41,165,522...41,335,917 		JBrowse link
G SNRPB small nuclear ribonucleoprotein polypeptides B and B1 severity ISO mRNA:increased expression:lung (human) RGD PMID:22876301 RGD:10768834 NCBI chr24:18,673,975...18,683,315
Ensembl chr24:18,674,039...18,683,229 		JBrowse link
G SNRPE small nuclear ribonucleoprotein polypeptide E severity ISO mRNA:increased expression:lung (human) RGD PMID:22876301 RGD:10768834 NCBI chr38:515,808...521,536
Ensembl chr38:515,860...521,535 		JBrowse link
G SNRPG small nuclear ribonucleoprotein polypeptide G ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr10:68,826,250...68,836,755
Ensembl chr10:68,826,250...68,836,755
Ensembl chr10:68,826,250...68,836,755 		JBrowse link
G SOD2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr 1:48,943,472...48,955,158
Ensembl chr 1:48,836,262...48,955,706 		JBrowse link
G SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:25741868 PMID:26619011 NCBI chr17:31,007,940...31,181,569
Ensembl chr17:31,009,257...31,142,063 		JBrowse link
G SOX2 SRY-box transcription factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25184679 NCBI chr34:14,853,000...14,855,153 JBrowse link
G SOX30 SRY-box transcription factor 30 disease_progression ISO RGD PMID:26330328 RGD:11535423 NCBI chr 4:52,587,163...52,615,945
Ensembl chr 4:52,587,355...52,615,945 		JBrowse link
G SOX4 SRY-box transcription factor 4 ISO protein:increased expression:lung RGD PMID:29882245 RGD:153297792 NCBI chr35:20,098,783...20,101,357
Ensembl chr35:20,099,773...20,101,154 		JBrowse link
G SPOP speckle type BTB/POZ protein ameliorates ISO human gene and cell line in mouse model
mRNA, protein:increased expression:lung (human)		 RGD PMID:30607139 PMID:31105033 RGD:153298920 RGD:153298927 NCBI chr 9:25,685,723...25,752,953
Ensembl chr 9:25,686,439...25,752,900 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase severity ISO RGD PMID:12826049 RGD:150521546 NCBI chr24:25,982,499...26,019,748
Ensembl chr24:25,999,048...26,018,077 		JBrowse link
G SRM spermidine synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 2:84,968,833...84,973,111
Ensembl chr 2:84,967,570...84,973,087 		JBrowse link
G SRR serine racemase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772
G SRSF1 serine and arginine rich splicing factor 1 severity ISO RGD PMID:23071587 RGD:150429662 NCBI chr 9:32,692,517...32,696,325
Ensembl chr 9:32,694,073...32,696,285 		JBrowse link
G SRSF2 serine and arginine rich splicing factor 2 severity ISO RGD PMID:23071587 RGD:150429662 NCBI chr 9:4,028,414...4,032,371
Ensembl chr 9:4,028,482...4,030,793 		JBrowse link
G STK11 serine/threonine kinase 11 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:10408777 PMID:12865922 PMID:15561763 PMID:15863673 PMID:16287113 More... NCBI chr20:57,558,966...57,579,163
Ensembl chr20:57,559,424...57,579,118 		JBrowse link
G STK39 serine/threonine kinase 39 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr36:12,866,867...13,118,736
Ensembl chr36:12,867,188...13,183,160 		JBrowse link
G STRBP spermatid perinuclear RNA binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 9:59,543,172...59,689,035
Ensembl chr 9:59,614,129...59,689,032 		JBrowse link
G SUCLG2 succinate-CoA ligase GDP-forming subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr20:23,915,149...24,167,740
Ensembl chr20:23,895,802...24,182,869 		JBrowse link
G SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 ISO DNA:SNP:exon:p.R213H, 638G>A (human) RGD PMID:14688021 RGD:1581441 NCBI chr 6:18,176,156...18,179,492
Ensembl chr 6:18,176,355...18,179,489 		JBrowse link
G TERT telomerase reverse transcriptase susceptibility ISO DNA:SNP:: rs2736100(human)
DNA:SNP::rs33963617(human)
DNA:SNPs:: rs2853669,rs2736108(human)
DNA:SNP: :rs2736098(human)		 RGD PMID:19955392 PMID:23738012 PMID:23908149 PMID:24761905 PMID:31935503 RGD:150530485 RGD:150530498 RGD:150530502 RGD:150530628 RGD:150530635 NCBI chr34:11,288,622...11,307,790
Ensembl chr34:11,288,622...11,307,951 		JBrowse link
G TGFB2 transforming growth factor beta 2 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr38:13,430,832...13,511,655
Ensembl chr38:13,429,148...13,510,242 		JBrowse link
G TIMM10 translocase of inner mitochondrial membrane 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr18:38,638,277...38,641,623
Ensembl chr18:38,638,696...38,641,623 		JBrowse link
G TIMM8A translocase of inner mitochondrial membrane 8A ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr  X:75,267,437...75,270,288
Ensembl chr  X:75,267,450...75,270,288 		JBrowse link
G TIMP3 TIMP metallopeptidase inhibitor 3 ISO mRNA:decreased expression:lung (human) RGD PMID:23374247 RGD:151708716 NCBI chr10:30,627,154...30,681,520
Ensembl chr10:30,627,154...30,694,288 		JBrowse link
G TK1 thymidine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 9:2,959,450...2,970,908
Ensembl chr 9:2,959,488...2,971,064 		JBrowse link
G TLR4 toll like receptor 4 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr11:71,356,390...71,367,166
Ensembl chr11:71,356,390...71,367,165 		JBrowse link
G TNFSF10 TNF superfamily member 10 ISO CTD Direct Evidence: therapeutic CTD PMID:24345465 NCBI chr34:36,719,249...36,734,989
Ensembl chr34:36,670,849...36,735,060 		JBrowse link
G TOMM40 translocase of outer mitochondrial membrane 40 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:110,530,233...110,541,049
Ensembl chr 1:110,530,597...110,541,042 		JBrowse link
G TOP2A DNA topoisomerase II alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 9:22,207,501...22,237,497
Ensembl chr 9:22,207,638...22,237,496 		JBrowse link
G TP53 tumor protein p53 ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Adenocarcinoma of lung, somatic | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:124622 PMID:253702 PMID:960674 PMID:1349175 PMID:1359493 More... NCBI chr 5:32,561,406...32,565,149
Ensembl chr 5:32,560,598...32,574,109 		JBrowse link
G TP63 tumor protein p63 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24880342 NCBI chr34:21,766,861...21,985,095
Ensembl chr34:21,766,496...21,983,046 		JBrowse link
G TPI1 triosephosphate isomerase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr27:38,154,519...38,157,900
Ensembl chr27:38,154,519...38,158,137 		JBrowse link
G TRAF4 TNF receptor associated factor 4 ISO mRNA:increased expression:lung (human) RGD PMID:29254206 RGD:151665107 NCBI chr 9:42,933,638...42,940,033
Ensembl chr 9:42,933,750...42,939,520 		JBrowse link
G TTF1 transcription termination factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25851810 NCBI chr 9:51,855,565...51,881,000
Ensembl chr 9:51,855,559...51,878,459 		JBrowse link
G TTR transthyretin ISO mRNA,protein:increased expression:lung (human) RGD PMID:26943652 RGD:151665207 NCBI chr 7:57,940,354...57,947,084
Ensembl chr 7:57,914,381...57,947,058 		JBrowse link
G TYMS thymidylate synthetase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 7:67,487,927...67,497,747
Ensembl chr 7:67,487,927...67,497,747 		JBrowse link
G U2AF1 U2 small nuclear RNA auxiliary factor 1 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:22158538 PMID:23029227 PMID:23861105 PMID:24498085 PMID:26619011 NCBI chr31:37,263,265...37,276,710 JBrowse link
G UBR5 ubiquitin protein ligase E3 component n-recognin 5 ameliorates ISO human cell line in a mouse model RGD PMID:32867711 RGD:151665200 NCBI chr13:3,887,408...4,023,364
Ensembl chr13:3,879,220...4,023,955 		JBrowse link
G UCK2 uridine-cytidine kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr38:17,475,789...17,555,926
Ensembl chr38:17,479,558...17,579,675 		JBrowse link
G VAV1 vav guanine nucleotide exchange factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr20:53,482,239...53,532,399
Ensembl chr20:53,482,498...53,531,296 		JBrowse link
G WRAP53 WD repeat containing antisense to TP53 severity ISO RGD PMID:28347242 RGD:21081522 NCBI chr 5:32,574,153...32,586,222
Ensembl chr 5:32,574,134...32,594,333 		JBrowse link
G XPC XPC complex subunit, DNA damage recognition and repair factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:21327329 PMID:27777383 NCBI chr20:4,299,644...4,328,826
Ensembl chr20:4,300,386...4,328,768 		JBrowse link
G XPO1 exportin 1 exacerbates ISO mRNA:increased expression:lung (human)
circRNA:increased expression:lung (human)		 RGD PMID:23639940 PMID:33268793 RGD:151665799 RGD:151665801 NCBI chr10:61,541,647...61,588,397
Ensembl chr10:61,542,211...61,585,054 		JBrowse link
G XRCC1 X-ray repair cross complementing 1 susceptibility
severity		 ISO DNA:missense mutation:cds: p.R399Q (human)
DNA:missense mutation:exon 10: p.R399Q (rs25487) (human)		 RGD PMID:11104903 PMID:20003463 RGD:151347406 RGD:151347422 NCBI chr 1:111,548,719...111,571,816
Ensembl chr 1:111,548,719...111,571,816 		JBrowse link
G XRCC5 X-ray repair cross complementing 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr37:23,095,769...23,185,680
Ensembl chr37:23,095,754...23,185,586 		JBrowse link
G XRCC6 X-ray repair cross complementing 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr10:23,637,905...23,661,618
Ensembl chr10:23,638,237...23,661,480 		JBrowse link
G ZFHX3 zinc finger homeobox 3 ameliorates ISO DNA:mutations:multiple (human) RGD PMID:32653938 RGD:151361163 NCBI chr 5:78,450,963...78,635,615
Ensembl chr 5:78,455,005...78,610,033 		JBrowse link
bronchiolo-alveolar adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALX4 ALX homeobox 4 ameliorates ISO RGD PMID:24037716 RGD:153344522 NCBI chr18:44,922,042...44,967,557
Ensembl chr18:44,922,150...44,967,550 		JBrowse link
G CCND1 cyclin D1 ISO protein:increased expression:lung RGD PMID:14674039 RGD:13434930 NCBI chr18:48,501,905...48,509,684
Ensembl chr18:48,501,899...48,516,005 		JBrowse link
G DNMT1 DNA methyltransferase 1 disease_progression ISO RGD PMID:19484794 RGD:4140940 NCBI chr20:50,872,213...50,928,352
Ensembl chr20:50,879,527...50,928,029 		JBrowse link
G EGFR epidermal growth factor receptor ISO DNA:mutations:exons:
protein:increased expression:tumor (human)
DNA:snp:cds:p.T790M (human)		 RGD PMID:15737014 PMID:21419590 PMID:26059825 RGD:11075076 RGD:5131465 RGD:5131630 NCBI chr18:5,983,669...6,044,092
Ensembl chr18:5,982,770...6,042,631 		JBrowse link
G EGR1 early growth response 1 ISO mRNA:decreased expression:tumor (human) RGD PMID:11948124 RGD:5131942 NCBI chr11:26,046,195...26,049,806
Ensembl chr11:26,046,228...26,048,575 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 ISO DNA:hypermethylation:promoter (human) RGD PMID:19484794 RGD:4140940 NCBI chr18:49,905,161...49,908,182
Ensembl chr18:49,905,161...49,908,182 		JBrowse link
G KRAS KRAS proto-oncogene, GTPase ISO DNA:mutations:cds: RGD PMID:26059825 RGD:11075076 NCBI chr27:22,261,753...22,296,704
Ensembl chr27:22,257,941...22,293,369 		JBrowse link
G MIR130A microRNA mir-130a ISO CTD Direct Evidence: marker/mechanism CTD PMID:25926378 NCBI chr18:38,543,618...38,543,679
Ensembl chr18:38,543,618...38,543,681 		JBrowse link
G MIR144 microRNA mir-144 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25926378 NCBI chr 9:43,031,035...43,031,094
Ensembl chr 9:43,031,035...43,031,094 		JBrowse link
G MIR19A microRNA mir-19a ISO CTD Direct Evidence: marker/mechanism CTD PMID:25926378 NCBI chr22:42,478,298...42,478,355
Ensembl chr22:42,478,285...42,478,366 		JBrowse link
G MIR345 microRNA mir-345 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25926378 NCBI chr 8:68,592,447...68,592,506 JBrowse link
G MIR497 microRNA mir-497 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25926378 NCBI chr 5:32,045,759...32,045,825
Ensembl chr 5:32,045,759...32,045,825 		JBrowse link
G TP53 tumor protein p53 ISO DNA:mutations:exons: RGD PMID:26059825 RGD:11075076 NCBI chr 5:32,561,406...32,565,149
Ensembl chr 5:32,560,598...32,574,109 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15603
    disease of cellular proliferation 7286
      cancer 5292
        cell type cancer 3646
          carcinoma 3100
            adenocarcinoma 1647
              lung adenocarcinoma 343
                bronchiolo-alveolar adenocarcinoma + 13
                lung acinar adenocarcinoma 0
                lung clear cell carcinoma 0
                lung mucinous cystadenocarcinoma 0
                lung occult adenocarcinoma 0
                lung papillary adenocarcinoma 0
                mucinous lung adenocarcinoma 0
                pulmonary adenocarcinoma in situ 0
                signet ring lung adenocarcinoma 0
                solid adenocarcinoma with mucin production 0
Path 2
Term Annotations click to browse term
  disease 15603
    disease of anatomical entity 15182
      respiratory system disease 3399
        thoracic disease 1858
          Thoracic Neoplasms 1436
            Respiratory Tract Neoplasms 1002
              Lung Neoplasms 980
                Bronchial Neoplasms 666
                  bronchus cancer 666
                    bronchus carcinoma 666
                      lung non-small cell carcinoma 629
                        lung adenocarcinoma 343
                          bronchiolo-alveolar adenocarcinoma + 13
                          lung acinar adenocarcinoma 0
                          lung clear cell carcinoma 0
                          lung mucinous cystadenocarcinoma 0
                          lung occult adenocarcinoma 0
                          lung papillary adenocarcinoma 0
                          mucinous lung adenocarcinoma 0
                          pulmonary adenocarcinoma in situ 0
                          signet ring lung adenocarcinoma 0
                          solid adenocarcinoma with mucin production 0
paths to the root