EGFR (epidermal growth factor receptor) - Rat Genome Database

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Advanced Search (OLGA)
Gene: EGFR (epidermal growth factor receptor) Canis lupus familiaris
Analyze
Symbol: EGFR
Name: epidermal growth factor receptor
RGD ID: 12340764
Description: ENCODES a protein that exhibits calmodulin binding (ortholog); epidermal growth factor binding (ortholog); epidermal growth factor receptor activity (ortholog); INVOLVED IN astrocyte activation (ortholog); cellular response to dexamethasone stimulus (ortholog); cellular response to epidermal growth factor stimulus (ortholog); PARTICIPATES IN altered epidermal growth factor/neuregulin signaling pathway; cetuximab pharmacodynamics pathway; E-cadherin signaling pathway; ASSOCIATED WITH acute kidney failure (ortholog); Acute Lung Injury (ortholog); adenocarcinoma (ortholog); FOUND IN apical plasma membrane (ortholog); basolateral plasma membrane (ortholog); cell surface (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1185,983,669 - 6,044,092 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl185,982,770 - 6,042,631 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha185,693,578 - 5,890,886 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0185,890,289 - 6,087,722 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl185,890,228 - 6,085,544 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1185,880,554 - 6,077,776 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0185,854,700 - 6,051,915 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0185,960,845 - 6,158,207 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
JBrowse:




Disease Annotations     Click to see Annotation Detail View
acute kidney failure  (ISO)
Acute Lung Injury  (ISO)
adenocarcinoma  (ISO)
adrenocortical carcinoma  (ISO)
Alcoholic Liver Diseases  (ISO)
Alzheimer's disease  (ISO)
Animal Mammary Neoplasms  (ISO)
aortic valve disease  (ISO)
aortic valve stenosis  (ISO)
arteriovenous malformations of the brain  (ISO)
asthma  (ISO)
autistic disorder  (ISO)
autosomal recessive polycystic kidney disease  (ISO)
Bannayan-Riley-Ruvalcaba syndrome  (ISO)
Bile Duct Neoplasms  (ISO)
breast cancer  (ISO)
breast carcinoma  (ISO)
Breast Neoplasms  (ISO)
bronchiolo-alveolar adenocarcinoma  (ISO)
carcinoma  (ISO)
Cardiomegaly  (ISO)
cerebral palsy  (ISO)
Chloracne  (ISO)
cholangiocarcinoma  (ISO)
chronic obstructive pulmonary disease  (ISO)
Colonic Neoplasms  (ISO)
colorectal cancer  (ISO)
Colorectal Neoplasms  (ISO)
Coronavirus infectious disease  (ISO)
Craniofacial Abnormalities  (ISO)
dementia  (ISO)
dermatitis  (ISO)
diabetes mellitus  (ISO)
diabetic retinopathy  (ISO)
dilated cardiomyopathy  (ISO)
Disease Progression  (ISO)
endometrial carcinoma  (ISO)
Endometrioid Carcinomas  (ISO)
endometriosis  (ISO)
Esophageal Neoplasms  (ISO)
esophagus squamous cell carcinoma  (ISO)
Experimental Arthritis  (ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Mammary Neoplasms  (ISO)
familial adenomatous polyposis  (ISO)
Gallbladder Neoplasms  (ISO)
glioblastoma  (ISO)
Head and Neck Neoplasms  (ISO)
head and neck squamous cell carcinoma  (ISO)
Helicobacter Infections  (ISO)
hepatocellular carcinoma  (ISO)
hereditary breast ovarian cancer syndrome  (ISO)
Hereditary Neoplastic Syndromes  (ISO)
high grade glioma  (ISO)
Huntington's disease  (ISO)
Hyperplasia  (ISO)
hypertension  (ISO)
Immediate Hypersensitivity  (ISO)
Inflammation  (ISO)
Insulin Resistance  (ISO)
Laryngeal Neoplasms  (ISO)
laryngeal squamous cell carcinoma  (ISO)
Left Ventricular Hypertrophy  (ISO)
leiomyoma  (ISO)
liver cirrhosis  (ISO)
lung adenocarcinoma  (ISO)
lung cancer  (ISO)
lung carcinoma  (ISO)
lung disease  (ISO)
Lung Neoplasms  (ISO)
lung non-small cell carcinoma  (ISO)
lung small cell carcinoma  (ISO)
lung squamous cell carcinoma  (ISO)
Lymphatic Metastasis  (ISO)
malignant mesothelioma  (ISO)
median neuropathy  (ISO)
Mesothelioma  (ISO)
Nasopharyngeal Neoplasms  (ISO)
Neonatal Inflammatory Skin and Bowel Disease 2  (ISO)
Neoplasm Invasiveness  (ISO)
Neoplasm Metastasis  (ISO)
Neoplasm Recurrence, Local  (ISO)
nicotine dependence  (ISO)
obesity  (ISO)
oral squamous cell carcinoma  (ISO)
osteosarcoma  (ISO)
ovarian cancer  (ISO)
Ovarian Neoplasms  (ISO)
pancreatic cancer  (ISO)
papilloma  (ISO)
papillomavirus infectious disease  (ISO)
Parkinson's disease  (ISO)
Parkinsonism  (ISO)
peptic esophagitis  (ISO)
Phyllodes Tumor  (ISO)
pleomorphic xanthoastrocytoma  (ISO)
prostate cancer  (ISO)
Prostatic Neoplasms  (ISO)
pulmonary fibrosis  (ISO)
pulmonary hypertension  (ISO)
Pulmonary Hypertension, Hypoxia-Induced  (ISO)
pulmonary tuberculosis  (ISO)
rectal benign neoplasm  (ISO)
renal cell carcinoma  (ISO)
Right Ventricular Hypertrophy  (ISO)
schizophrenia  (ISO)
severe acute respiratory syndrome  (ISO)
Spinal Cord Injuries  (ISO)
squamous cell carcinoma  (ISO)
stomach cancer  (ISO)
Stomach Neoplasms  (ISO)
tongue squamous cell carcinoma  (ISO)
transitional cell carcinoma  (ISO)
type 1 diabetes mellitus  (ISO)
type 2 diabetes mellitus  (ISO)
urinary bladder cancer  (ISO)
Uterine Cervical Neoplasms  (ISO)
Vascular Remodeling  (ISO)
Ventricular Fibrillation  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
astrocyte activation  (ISO)
cell morphogenesis  (IEA)
cell population proliferation  (IEA)
cell surface receptor protein tyrosine kinase signaling pathway  (IEA)
cell surface receptor signaling pathway  (IEA)
cell-cell adhesion  (IEA)
cellular response to amino acid stimulus  (IEA)
cellular response to dexamethasone stimulus  (ISO)
cellular response to epidermal growth factor stimulus  (ISO)
cellular response to estradiol stimulus  (IEA)
cellular response to growth factor stimulus  (IEA,ISO)
cellular response to mechanical stimulus  (ISO)
cellular response to xenobiotic stimulus  (ISO)
cerebral cortex cell migration  (IEA)
circadian rhythm  (ISO)
digestive tract morphogenesis  (IEA)
diterpenoid metabolic process  (ISO)
embryonic placenta development  (IEA)
epidermal growth factor receptor signaling pathway  (IBA,IEA,ISO)
epidermis development  (IEA)
epithelial cell proliferation  (IEA)
ERBB2-EGFR signaling pathway  (IEA)
eyelid development in camera-type eye  (IEA)
gene expression  (ISO)
hair follicle development  (IEA,ISO)
hydrogen peroxide metabolic process  (ISO)
intracellular signal transduction  (ISO)
learning or memory  (ISO)
liver development  (ISO)
liver regeneration  (ISO)
lung development  (ISO)
midgut development  (ISO)
morphogenesis of an epithelial fold  (IEA)
negative regulation of apoptotic process  (IBA,IEA,ISO)
negative regulation of cardiocyte differentiation  (IEA)
negative regulation of epidermal growth factor receptor signaling pathway  (IEA,ISO)
negative regulation of mitotic cell cycle  (ISO)
negative regulation of protein catabolic process  (IEA)
neuron differentiation  (IBA)
neuron projection morphogenesis  (ISO)
ovulation cycle  (ISO)
peptidyl-tyrosine phosphorylation  (ISO)
phosphatidylinositol 3-kinase/protein kinase B signal transduction  (IEA)
positive regulation of bone resorption  (ISO)
positive regulation of canonical Wnt signaling pathway  (IEA)
positive regulation of cell growth  (IEA)
positive regulation of cell migration  (IEA)
positive regulation of cell population proliferation  (IEA,ISO)
positive regulation of DNA repair  (IEA)
positive regulation of DNA replication  (IEA)
positive regulation of epidermal growth factor receptor signaling pathway  (ISO)
positive regulation of epithelial cell proliferation  (IBA,IEA)
positive regulation of ERK1 and ERK2 cascade  (IEA)
positive regulation of fibroblast proliferation  (IEA)
positive regulation of G1/S transition of mitotic cell cycle  (IEA)
positive regulation of glial cell proliferation  (ISO)
positive regulation of MAPK cascade  (IBA,IEA,ISO)
positive regulation of miRNA transcription  (IEA)
positive regulation of mucus secretion  (ISO)
positive regulation of peptidyl-serine phosphorylation  (ISO)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction  (IEA)
positive regulation of phosphorylation  (IEA)
positive regulation of prolactin secretion  (ISO)
positive regulation of protein kinase C signaling  (IEA)
positive regulation of protein localization to plasma membrane  (IEA)
positive regulation of protein phosphorylation  (ISO)
positive regulation of smooth muscle cell proliferation  (ISO)
positive regulation of superoxide anion generation  (ISO)
positive regulation of synaptic transmission, glutamatergic  (ISO)
positive regulation of transcription by RNA polymerase II  (IEA)
positive regulation of vasoconstriction  (ISO)
protein autophosphorylation  (ISO)
protein ubiquitination  (ISO)
receptor-mediated endocytosis  (ISO)
regulation of cell population proliferation  (IEA)
regulation of peptidyl-tyrosine phosphorylation  (ISO)
response to calcium ion  (ISO)
response to cobalamin  (ISO)
response to estradiol  (ISO)
response to hydroxyisoflavone  (ISO)
response to lipid  (ISO)
response to oxidative stress  (ISO)
response to UV-A  (IEA)
salivary gland morphogenesis  (IEA)
signal transduction  (IEA)
tongue development  (ISO)
translation  (ISO)
ubiquitin-dependent endocytosis  (ISO)
ubiquitin-dependent protein catabolic process  (ISO)
vasodilation  (ISO)
xenobiotic transport  (ISO)

References
Additional References at PubMed
PMID:17643426   PMID:17848576   PMID:17855771   PMID:18057028   PMID:19101024   PMID:19464036   PMID:20832399   PMID:21212278   PMID:22235915   PMID:22301074   PMID:22994149   PMID:24060154  
PMID:24421325   PMID:25223345   PMID:25964576   PMID:26483386   PMID:26498203   PMID:27490467   PMID:30032202   PMID:32877289   PMID:33926328   PMID:37756605  


Genomics

Comparative Map Data
EGFR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1185,983,669 - 6,044,092 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl185,982,770 - 6,042,631 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha185,693,578 - 5,890,886 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0185,890,289 - 6,087,722 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl185,890,228 - 6,085,544 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1185,880,554 - 6,077,776 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0185,854,700 - 6,051,915 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0185,960,845 - 6,158,207 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
EGFR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38755,019,017 - 55,211,628 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl755,019,017 - 55,211,628 (+)Ensemblhg38GRCh38
GRCh37755,086,710 - 55,279,321 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36755,054,219 - 55,242,525 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34754,860,933 - 55,012,947NCBI
Celera755,192,332 - 55,380,657 (+)NCBICelera
Cytogenetic Map7p11.2NCBI
HuRef754,924,934 - 55,112,834 (+)NCBIHuRef
CHM1_1755,089,165 - 55,277,398 (+)NCBICHM1_1
T2T-CHM13v2.0755,178,937 - 55,372,056 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2755,092,507 - 55,280,831 (+)NCBI
Egfr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391116,700,153 - 16,868,158 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1116,702,203 - 16,868,158 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381116,752,203 - 16,913,907 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1116,752,203 - 16,918,158 (+)Ensemblmm10GRCm38
MGSCv371116,652,206 - 16,813,910 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361116,652,206 - 16,813,909 (+)NCBIMGSCv36mm8
Celera1117,126,474 - 17,287,898 (+)NCBICelera
Cytogenetic Map11A2NCBI
cM Map119.41NCBI
Egfr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81495,378,626 - 95,551,358 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1495,378,626 - 95,551,358 (+)EnsemblGRCr8
mRatBN7.21491,176,979 - 91,349,722 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1491,177,067 - 91,344,382 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1495,489,293 - 95,663,168 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01496,733,623 - 96,907,493 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01493,198,702 - 93,372,564 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01499,919,485 - 100,104,136 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1499,919,485 - 100,098,796 (+)Ensemblrn6Rnor6.0
Rnor_5.014100,438,989 - 100,617,315 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41497,617,358 - 97,788,211 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1490,225,928 - 90,392,779 (+)NCBICelera
RH 3.4 Map14 RGD
Cytogenetic Map14q22NCBI
Egfr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955456321,222 - 371,701 (-)Ensembl
ChiLan1.0NW_004955456321,222 - 456,431 (-)NCBIChiLan1.0ChiLan1.0
EGFR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2659,852,898 - 60,046,419 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17108,177,622 - 108,371,205 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0755,614,042 - 55,807,285 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1756,048,212 - 56,117,642 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl756,046,296 - 56,111,615 (+)EnsemblpanPan2panpan1.1
Egfr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118109,328,850 - 109,524,551 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936678365,834 - 436,528 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936678365,005 - 560,546 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EGFR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9139,300,022 - 139,475,589 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.19139,302,410 - 139,474,632 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
EGFR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1213,664,622 - 3,853,492 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl213,666,339 - 3,853,239 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366606218,644,141 - 18,836,149 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Egfr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624740589,606 - 713,271 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624740584,133 - 713,205 (-)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in EGFR
852 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_022405164 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038423674 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038423675 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038423676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038453716 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038453718 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038453719 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038500041 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038500042 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038500043 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038562623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038562624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038562625 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038626703 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038626704 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038626705 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY527212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCAFT00000005575   ⟹   ENSCAFP00000005164
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl185,982,770 - 6,042,631 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000061399   ⟹   ENSCAFP00000060376
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl185,982,770 - 6,042,631 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845020211   ⟹   ENSCAFP00845015842
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl185,890,228 - 6,084,333 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845020269   ⟹   ENSCAFP00845015889
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl185,890,266 - 6,085,544 (+)Ensembl
RefSeq Acc Id: XM_038423674   ⟹   XP_038279602
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0185,890,289 - 6,087,722 (+)NCBI
RefSeq Acc Id: XM_038423675   ⟹   XP_038279603
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0185,949,990 - 6,087,722 (+)NCBI
RefSeq Acc Id: XM_038423676   ⟹   XP_038279604
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0185,904,007 - 6,087,722 (+)NCBI
RefSeq Acc Id: XM_038453716   ⟹   XP_038309644
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha185,693,578 - 5,890,886 (+)NCBI
RefSeq Acc Id: XM_038453718   ⟹   XP_038309646
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha185,753,259 - 5,890,886 (+)NCBI
RefSeq Acc Id: XM_038453719   ⟹   XP_038309647
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha185,707,290 - 5,890,886 (+)NCBI
RefSeq Acc Id: XM_038500041   ⟹   XP_038355969
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1185,880,554 - 6,077,776 (+)NCBI
RefSeq Acc Id: XM_038500042   ⟹   XP_038355970
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1185,940,177 - 6,077,776 (+)NCBI
RefSeq Acc Id: XM_038500043   ⟹   XP_038355971
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1185,894,249 - 6,077,776 (+)NCBI
RefSeq Acc Id: XM_038562623   ⟹   XP_038418551
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0185,960,845 - 6,158,207 (+)NCBI
RefSeq Acc Id: XM_038562624   ⟹   XP_038418552
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0186,020,575 - 6,158,207 (+)NCBI
RefSeq Acc Id: XM_038562625   ⟹   XP_038418553
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0185,974,557 - 6,158,207 (+)NCBI
RefSeq Acc Id: XM_038626703   ⟹   XP_038482631
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0185,854,700 - 6,051,915 (+)NCBI
RefSeq Acc Id: XM_038626704   ⟹   XP_038482632
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0185,914,344 - 6,051,915 (+)NCBI
RefSeq Acc Id: XM_038626705   ⟹   XP_038482633
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0185,868,386 - 6,051,915 (+)NCBI
Ensembl Acc Id: ENSCAFP00000005164   ⟸   ENSCAFT00000005575
Ensembl Acc Id: ENSCAFP00000060376   ⟸   ENSCAFT00000061399
RefSeq Acc Id: XP_038355969   ⟸   XM_038500041
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038355971   ⟸   XM_038500043
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038355970   ⟸   XM_038500042
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038482631   ⟸   XM_038626703
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038482633   ⟸   XM_038626705
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038482632   ⟸   XM_038626704
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038279602   ⟸   XM_038423674
- Peptide Label: isoform X1
- UniProtKB: A0A8C0RE23 (UniProtKB/TrEMBL),   A0A8I3RYJ5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038279604   ⟸   XM_038423676
- Peptide Label: isoform X2
- UniProtKB: A0A8D6L9C2 (UniProtKB/TrEMBL),   A0A8C0LIX3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038279603   ⟸   XM_038423675
- Peptide Label: isoform X2
- UniProtKB: A0A8D6L9C2 (UniProtKB/TrEMBL),   A0A8C0LIX3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038309644   ⟸   XM_038453716
- Peptide Label: isoform X1
- UniProtKB: A0A8C0RE23 (UniProtKB/TrEMBL),   A0A8I3RYJ5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038309647   ⟸   XM_038453719
- Peptide Label: isoform X2
- UniProtKB: A0A8D6L9C2 (UniProtKB/TrEMBL),   A0A8C0LIX3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038309646   ⟸   XM_038453718
- Peptide Label: isoform X2
- UniProtKB: A0A8D6L9C2 (UniProtKB/TrEMBL),   A0A8C0LIX3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038418551   ⟸   XM_038562623
- Peptide Label: isoform X1
- UniProtKB: A0A8C0RE23 (UniProtKB/TrEMBL),   A0A8I3RYJ5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038418553   ⟸   XM_038562625
- Peptide Label: isoform X2
- UniProtKB: A0A8C0LIX3 (UniProtKB/TrEMBL),   A0A8D6L9C2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038418552   ⟸   XM_038562624
- Peptide Label: isoform X2
- UniProtKB: A0A8C0LIX3 (UniProtKB/TrEMBL),   A0A8D6L9C2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845015842   ⟸   ENSCAFT00845020211
Ensembl Acc Id: ENSCAFP00845015889   ⟸   ENSCAFT00845020269
Protein Domains
Protein kinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000003465 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030006284 UniProtKB/TrEMBL
  ENSCAFG00845011396 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000005575.5 UniProtKB/TrEMBL
  ENSCAFT00000061399.2 UniProtKB/TrEMBL
  ENSCAFT00030011953.1 UniProtKB/TrEMBL
  ENSCAFT00030012255.1 UniProtKB/TrEMBL
  ENSCAFT00845020211.1 UniProtKB/TrEMBL
  ENSCAFT00845020269 ENTREZGENE
  ENSCAFT00845020269.1 UniProtKB/TrEMBL
Gene3D-CATH 3.80.20.20 UniProtKB/TrEMBL
  6.10.250.2930 UniProtKB/TrEMBL
  Hormone Receptor, Insulin-like Growth Factor Receptor 1, Chain A, domain 2 UniProtKB/TrEMBL
  Phosphorylase Kinase, domain 1 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Egfr_JX_dom UniProtKB/TrEMBL
  Furin-like_Cys-rich_dom UniProtKB/TrEMBL
  Furin_repeat UniProtKB/TrEMBL
  GF_recep_IV UniProtKB/TrEMBL
  Growth_fac_rcpt_cys_sf UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Rcpt_L-dom UniProtKB/TrEMBL
  Rcpt_L-dom_sf UniProtKB/TrEMBL
  RTK UniProtKB/TrEMBL
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/TrEMBL
  TM_ErbB1 UniProtKB/TrEMBL
  Tyr_kinase_AS UniProtKB/TrEMBL
  Tyr_kinase_cat_dom UniProtKB/TrEMBL
  Tyr_kinase_EGF/ERB/XmrK_rcpt UniProtKB/TrEMBL
NCBI Gene EGFR ENTREZGENE
PANTHER EPIDERMAL GROWTH FACTOR RECEPTOR UniProtKB/TrEMBL
  TYROSINE-PROTEIN KINASE RECEPTOR UniProtKB/TrEMBL
Pfam Furin-like UniProtKB/TrEMBL
  GF_recep_IV UniProtKB/TrEMBL
  PK_Tyr_Ser-Thr UniProtKB/TrEMBL
  Recep_L_domain UniProtKB/TrEMBL
  TM_ErbB1 UniProtKB/TrEMBL
PIRSF TyrPK_EGF-R UniProtKB/TrEMBL
PRINTS TYRKINASE UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_TYR UniProtKB/TrEMBL
SMART SM00261 UniProtKB/TrEMBL
  TyrKc UniProtKB/TrEMBL
Superfamily-SCOP L domain-like UniProtKB/TrEMBL
  SSF56112 UniProtKB/TrEMBL
  SSF57184 UniProtKB/TrEMBL
UniProt A0A8C0LIX3 ENTREZGENE
  A0A8C0MID8_CANLF UniProtKB/TrEMBL
  A0A8C0RE23 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D6L9C2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NJD5_CANLF UniProtKB/TrEMBL
  A0A8I3RYJ5 ENTREZGENE, UniProtKB/TrEMBL
  Q6QT04_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:51866 ENTREZGENE