Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References FTP Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer ACP Haplotyper Genome Scanner
Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: EGFR (epidermal growth factor receptor) Canis lupus familiaris
Analyze
Symbol: EGFR
Name: epidermal growth factor receptor
Description: ENCODES a protein that exhibits calmodulin binding (ortholog); enzyme binding (ortholog); integrin binding (ortholog); INVOLVED IN activation of MAPKK activity (ortholog); astrocyte activation (ortholog); cell surface receptor signaling pathway (ortholog); PARTICIPATES IN cetuximab pharmacodynamics pathway; E-cadherin signaling pathway; eicosanoid signaling pathway; ASSOCIATED WITH acute kidney failure (ortholog); Acute Lung Injury (ortholog); adenocarcinoma (ortholog); FOUND IN apical plasma membrane (ortholog); basolateral plasma membrane (ortholog); cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
Orthologs:
Homo sapiens (human) : EGFR (epidermal growth factor receptor)  HGNC  Alliance
Mus musculus (house mouse) : Egfr (epidermal growth factor receptor)  MGI  Alliance
Rattus norvegicus (Norway rat) : Egfr (epidermal growth factor receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Egfr (epidermal growth factor receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : EGFR (epidermal growth factor receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Egfr (epidermal growth factor receptor)
Sus scrofa (pig) : EGFR (epidermal growth factor receptor)
Chlorocebus sabaeus (African green monkey) : EGFR (epidermal growth factor receptor)
Heterocephalus glaber (naked mole-rat) : Egfr (epidermal growth factor receptor)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl185,982,770 - 6,042,631 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1185,983,669 - 6,044,092 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)
Model

Annotation    (Toggle Annotation Detail/Summary View)

Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated

Genomics

Comparative Map Data

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
  
More on EGFR
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 12340764
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2020-07-01
Status: ACTIVE



Contact Us |  About Us |  License CC BY 4.0 |  Legal Disclaimer |  © Medical College of Wisconsin
NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.