NLRP3 (NLR family pyrin domain containing 3) - Rat Genome Database

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Gene: NLRP3 (NLR family pyrin domain containing 3) Canis lupus familiaris
Analyze
Symbol: NLRP3
Name: NLR family pyrin domain containing 3
RGD ID: 12364239
Description: ENCODES a protein that exhibits DNA-binding transcription factor binding (ortholog); sequence-specific DNA binding (ortholog); INVOLVED IN activation of cysteine-type endopeptidase activity involved in apoptotic process (ortholog); acute inflammatory response (ortholog); cellular response to peptidoglycan (ortholog); PARTICIPATES IN interleukin-1 signaling pathway; ASSOCIATED WITH acne (ortholog); Acute Lung Injury (ortholog); alcoholic hepatitis (ortholog); FOUND IN cytoplasm (ortholog); inflammasome complex (ortholog); NLRP3 inflammasome complex (ortholog); INTERACTS WITH ochratoxin A
Type: protein-coding
RefSeq Status: MODEL
Previously known as: NACHT, LRR and PYD domains-containing protein 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.18251,776 - 313,290 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl8253,407 - 313,059 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha8277,639 - 339,097 (+)NCBI
ROS_Cfam_1.08299,639 - 361,123 (+)NCBI
ROS_Cfam_1.0 Ensembl8301,633 - 360,913 (+)Ensembl
UMICH_Zoey_3.18242,540 - 300,444 (+)NCBI
UNSW_CanFamBas_1.08204,531 - 262,443 (+)NCBI
UU_Cfam_GSD_1.08337,026 - 389,302 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
ochratoxin A  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
activation of cysteine-type endopeptidase activity involved in apoptotic process  (ISO)
acute inflammatory response  (ISO)
cellular response to lipopolysaccharide  (IEA)
cellular response to peptidoglycan  (ISO)
cellular response to virus  (IEA)
defense response to Gram-positive bacterium  (ISO)
defense response to virus  (ISO)
inflammatory response  (IEA)
leukocyte migration involved in inflammatory response  (ISO)
negative regulation of acute inflammatory response  (IEA)
negative regulation of inflammatory response  (ISO)
negative regulation of interleukin-1 beta production  (IEA)
negative regulation of NF-kappaB transcription factor activity  (IEA)
negative regulation of NIK/NF-kappaB signaling  (IBA)
NLRP3 inflammasome complex assembly  (IEA,ISO)
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process  (IBA)
positive regulation of cytokine production involved in immune response  (ISO)
positive regulation of interleukin-1 beta production  (IEA,ISO)
positive regulation of interleukin-13 production  (ISO)
positive regulation of interleukin-4 production  (ISO)
positive regulation of interleukin-5 production  (ISO)
positive regulation of NF-kappaB transcription factor activity  (IEA)
positive regulation of T-helper 17 cell differentiation  (ISO)
positive regulation of T-helper 2 cell cytokine production  (ISO)
positive regulation of T-helper 2 cell differentiation  (ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
positive regulation of type 2 immune response  (ISO)
regulation of inflammatory response  (ISO)
response to ethanol  (ISO)
response to organic cyclic compound  (ISO)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
NLRP3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.18251,776 - 313,290 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl8253,407 - 313,059 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha8277,639 - 339,097 (+)NCBI
ROS_Cfam_1.08299,639 - 361,123 (+)NCBI
ROS_Cfam_1.0 Ensembl8301,633 - 360,913 (+)Ensembl
UMICH_Zoey_3.18242,540 - 300,444 (+)NCBI
UNSW_CanFamBas_1.08204,531 - 262,443 (+)NCBI
UU_Cfam_GSD_1.08337,026 - 389,302 (+)NCBI
NLRP3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381247,416,077 - 247,448,817 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1247,416,156 - 247,449,108 (+)EnsemblGRCh38hg38GRCh38
GRCh371247,579,475 - 247,612,119 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361245,646,098 - 245,679,033 (+)NCBINCBI36hg18NCBI36
Build 341243,907,391 - 243,938,445NCBI
Celera1220,878,780 - 220,911,159 (+)NCBI
Cytogenetic Map1q44NCBI
HuRef1217,973,841 - 218,006,798 (+)NCBIHuRef
CHM1_11248,851,104 - 248,884,745 (+)NCBICHM1_1
T2T-CHM13v2.01246,852,663 - 246,885,459 (+)NCBI
Nlrp3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391159,432,395 - 59,457,781 (+)NCBIGRCm39mm39
GRCm39 Ensembl1159,432,394 - 59,457,782 (+)Ensembl
GRCm381159,541,569 - 59,566,955 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1159,541,568 - 59,566,956 (+)EnsemblGRCm38mm10GRCm38
MGSCv371159,356,188 - 59,380,458 (+)NCBIGRCm37mm9NCBIm37
MGSCv361160,078,786 - 60,103,056 (+)NCBImm8
MGSCv361159,358,881 - 59,383,151 (+)NCBImm8
Cytogenetic Map11B1.3NCBI
Nlrp3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21044,326,770 - 44,353,814 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1044,328,566 - 44,352,811 (+)Ensembl
Rnor_6.01045,884,324 - 45,918,290 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1045,893,018 - 45,918,254 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01045,648,191 - 45,674,617 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41045,850,224 - 45,874,533 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11045,864,282 - 45,887,837 (+)NCBI
Celera1043,590,413 - 43,614,602 (+)NCBICelera
Cytogenetic Map10q22NCBI
Nlrp3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955581597,667 - 617,410 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955581597,952 - 616,903 (+)NCBIChiLan1.0ChiLan1.0
NLRP3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11228,505,147 - 228,537,216 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1228,505,147 - 228,537,216 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01223,052,307 - 223,084,736 (+)NCBIMhudiblu_PPA_v0panPan3
Nlrp3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721388,366,531 - 88,390,960 (+)NCBI
SpeTri2.0NW_004936864709,693 - 732,119 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NLRP3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl256,892,243 - 56,977,228 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1256,892,241 - 56,977,412 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2257,789,084 - 57,873,272 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NLRP3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12584,431,436 - 84,463,387 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2584,434,527 - 84,463,249 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605586,817,681 - 86,848,042 (+)NCBIVero_WHO_p1.0
Nlrp3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624937564,191 - 584,470 (-)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium
Low 7 3 6 3 4 5 5 5
Below cutoff 5 5 15 3 3 2 6 7 8 5 1

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005623148 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005623149 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005623150 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038482671 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038482672 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038482673 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038482674 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038482675 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038482676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038482677 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038482678 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038482679 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038482680 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038482681 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038544093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038544094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038544095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038544096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038544097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038544098 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038544099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038544100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038544101 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038544102 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038544103 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038582545 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038582546 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038582552 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038582566 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038582575 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038582583 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038582596 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038608220 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038608221 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038608222 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038608223 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038608224 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038608225 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038608226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038608227 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038608228 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038608229 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038608230 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038673023 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038673024 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038673025 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038673026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038673027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038673028 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038673029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038673030 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038673031 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038673032 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038673033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_843284 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000086 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000017002   ⟹   ENSCAFP00000015730
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl8253,407 - 313,059 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000068646   ⟹   ENSCAFP00000056038
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl8253,407 - 313,059 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000070287   ⟹   ENSCAFP00000044134
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl8253,407 - 313,059 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000091465   ⟹   ENSCAFP00000058017
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl8253,789 - 313,059 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845032436   ⟹   ENSCAFP00845025361
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl8301,633 - 360,913 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845032499   ⟹   ENSCAFP00845025412
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl8301,633 - 360,913 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845032568   ⟹   ENSCAFP00845025471
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl8301,633 - 360,913 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845032636   ⟹   ENSCAFP00845025523
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl8301,633 - 360,913 (+)Ensembl
RefSeq Acc Id: XM_005623148   ⟹   XP_005623205
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.18251,777 - 313,290 (+)NCBI
Dog10K_Boxer_Tasha8277,639 - 339,097 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005623149   ⟹   XP_005623206
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.18251,776 - 313,290 (+)NCBI
Dog10K_Boxer_Tasha8277,639 - 339,097 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005623150   ⟹   XP_005623207
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.18251,776 - 313,290 (+)NCBI
Dog10K_Boxer_Tasha8277,639 - 339,097 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038482671   ⟹   XP_038338599
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.18242,540 - 300,444 (+)NCBI
RefSeq Acc Id: XM_038482672   ⟹   XP_038338600
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.18244,165 - 300,444 (+)NCBI
RefSeq Acc Id: XM_038482673   ⟹   XP_038338601
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.18242,565 - 300,444 (+)NCBI
RefSeq Acc Id: XM_038482674   ⟹   XP_038338602
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.18242,540 - 300,444 (+)NCBI
RefSeq Acc Id: XM_038482675   ⟹   XP_038338603
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.18242,540 - 300,444 (+)NCBI
RefSeq Acc Id: XM_038482676   ⟹   XP_038338604
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.18242,540 - 300,444 (+)NCBI
RefSeq Acc Id: XM_038482677   ⟹   XP_038338605
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.18242,540 - 300,444 (+)NCBI
RefSeq Acc Id: XM_038482678   ⟹   XP_038338606
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.18244,722 - 300,444 (+)NCBI
RefSeq Acc Id: XM_038482679   ⟹   XP_038338607
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.18244,636 - 300,444 (+)NCBI
RefSeq Acc Id: XM_038482680   ⟹   XP_038338608
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.18242,540 - 300,444 (+)NCBI
RefSeq Acc Id: XM_038482681   ⟹   XP_038338609
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.18242,540 - 300,444 (+)NCBI
RefSeq Acc Id: XM_038544093   ⟹   XP_038400021
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.08337,026 - 389,302 (+)NCBI
RefSeq Acc Id: XM_038544094   ⟹   XP_038400022
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.08338,652 - 389,302 (+)NCBI
RefSeq Acc Id: XM_038544095   ⟹   XP_038400023
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.08337,051 - 389,302 (+)NCBI
RefSeq Acc Id: XM_038544096   ⟹   XP_038400024
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.08337,026 - 389,302 (+)NCBI
RefSeq Acc Id: XM_038544097   ⟹   XP_038400025
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.08337,026 - 389,302 (+)NCBI
RefSeq Acc Id: XM_038544098   ⟹   XP_038400026
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.08337,026 - 389,302 (+)NCBI
RefSeq Acc Id: XM_038544099   ⟹   XP_038400027
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.08337,026 - 389,302 (+)NCBI
RefSeq Acc Id: XM_038544100   ⟹   XP_038400028
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.08339,209 - 389,302 (+)NCBI
RefSeq Acc Id: XM_038544101   ⟹   XP_038400029
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.08339,123 - 389,302 (+)NCBI
RefSeq Acc Id: XM_038544102   ⟹   XP_038400030
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.08337,026 - 389,302 (+)NCBI
RefSeq Acc Id: XM_038544103   ⟹   XP_038400031
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.08337,026 - 389,302 (+)NCBI
RefSeq Acc Id: XM_038582545   ⟹   XP_038438473
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha8279,265 - 339,097 (+)NCBI
RefSeq Acc Id: XM_038582546   ⟹   XP_038438474
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha8277,666 - 339,097 (+)NCBI
RefSeq Acc Id: XM_038582552   ⟹   XP_038438480
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha8277,639 - 339,097 (+)NCBI
RefSeq Acc Id: XM_038582566   ⟹   XP_038438494
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha8277,639 - 339,097 (+)NCBI
RefSeq Acc Id: XM_038582575   ⟹   XP_038438503
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha8279,822 - 339,097 (+)NCBI
RefSeq Acc Id: XM_038582583   ⟹   XP_038438511
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha8279,736 - 339,097 (+)NCBI
RefSeq Acc Id: XM_038582596   ⟹   XP_038438524
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha8277,639 - 339,097 (+)NCBI
RefSeq Acc Id: XM_038608220   ⟹   XP_038464148
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.08204,531 - 262,443 (+)NCBI
RefSeq Acc Id: XM_038608221   ⟹   XP_038464149
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.08206,156 - 262,443 (+)NCBI
RefSeq Acc Id: XM_038608222   ⟹   XP_038464150
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.08204,556 - 262,443 (+)NCBI
RefSeq Acc Id: XM_038608223   ⟹   XP_038464151
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.08204,531 - 262,443 (+)NCBI
RefSeq Acc Id: XM_038608224   ⟹   XP_038464152
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.08204,531 - 262,443 (+)NCBI
RefSeq Acc Id: XM_038608225   ⟹   XP_038464153
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.08204,531 - 262,443 (+)NCBI
RefSeq Acc Id: XM_038608226   ⟹   XP_038464154
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.08204,531 - 262,443 (+)NCBI
RefSeq Acc Id: XM_038608227   ⟹   XP_038464155
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.08206,713 - 262,443 (+)NCBI
RefSeq Acc Id: XM_038608228   ⟹   XP_038464156
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.08206,627 - 262,443 (+)NCBI
RefSeq Acc Id: XM_038608229   ⟹   XP_038464157
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.08204,531 - 262,443 (+)NCBI
RefSeq Acc Id: XM_038608230   ⟹   XP_038464158
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.08204,531 - 262,443 (+)NCBI
RefSeq Acc Id: XM_038673023   ⟹   XP_038528951
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.08299,639 - 361,123 (+)NCBI
RefSeq Acc Id: XM_038673024   ⟹   XP_038528952
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.08301,266 - 361,123 (+)NCBI
RefSeq Acc Id: XM_038673025   ⟹   XP_038528953
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.08299,664 - 361,123 (+)NCBI
RefSeq Acc Id: XM_038673026   ⟹   XP_038528954
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.08299,639 - 361,123 (+)NCBI
RefSeq Acc Id: XM_038673027   ⟹   XP_038528955
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.08299,639 - 361,123 (+)NCBI
RefSeq Acc Id: XM_038673028   ⟹   XP_038528956
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.08299,639 - 361,123 (+)NCBI
RefSeq Acc Id: XM_038673029   ⟹   XP_038528957
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.08299,639 - 361,123 (+)NCBI
RefSeq Acc Id: XM_038673030   ⟹   XP_038528958
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.08301,823 - 361,123 (+)NCBI
RefSeq Acc Id: XM_038673031   ⟹   XP_038528959
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.08301,737 - 361,123 (+)NCBI
RefSeq Acc Id: XM_038673032   ⟹   XP_038528960
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.08299,639 - 361,123 (+)NCBI
RefSeq Acc Id: XM_038673033   ⟹   XP_038528961
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.08299,639 - 361,123 (+)NCBI
RefSeq Acc Id: XM_843284   ⟹   XP_848377
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.18251,777 - 313,290 (+)NCBI
Dog10K_Boxer_Tasha8277,639 - 339,097 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005623205 (Get FASTA)   NCBI Sequence Viewer  
  XP_005623206 (Get FASTA)   NCBI Sequence Viewer  
  XP_005623207 (Get FASTA)   NCBI Sequence Viewer  
  XP_038338599 (Get FASTA)   NCBI Sequence Viewer  
  XP_038338600 (Get FASTA)   NCBI Sequence Viewer  
  XP_038338601 (Get FASTA)   NCBI Sequence Viewer  
  XP_038338602 (Get FASTA)   NCBI Sequence Viewer  
  XP_038338603 (Get FASTA)   NCBI Sequence Viewer  
  XP_038338604 (Get FASTA)   NCBI Sequence Viewer  
  XP_038338605 (Get FASTA)   NCBI Sequence Viewer  
  XP_038338606 (Get FASTA)   NCBI Sequence Viewer  
  XP_038338607 (Get FASTA)   NCBI Sequence Viewer  
  XP_038338608 (Get FASTA)   NCBI Sequence Viewer  
  XP_038338609 (Get FASTA)   NCBI Sequence Viewer  
  XP_038400021 (Get FASTA)   NCBI Sequence Viewer  
  XP_038400022 (Get FASTA)   NCBI Sequence Viewer  
  XP_038400023 (Get FASTA)   NCBI Sequence Viewer  
  XP_038400024 (Get FASTA)   NCBI Sequence Viewer  
  XP_038400025 (Get FASTA)   NCBI Sequence Viewer  
  XP_038400026 (Get FASTA)   NCBI Sequence Viewer  
  XP_038400027 (Get FASTA)   NCBI Sequence Viewer  
  XP_038400028 (Get FASTA)   NCBI Sequence Viewer  
  XP_038400029 (Get FASTA)   NCBI Sequence Viewer  
  XP_038400030 (Get FASTA)   NCBI Sequence Viewer  
  XP_038400031 (Get FASTA)   NCBI Sequence Viewer  
  XP_038438473 (Get FASTA)   NCBI Sequence Viewer  
  XP_038438474 (Get FASTA)   NCBI Sequence Viewer  
  XP_038438480 (Get FASTA)   NCBI Sequence Viewer  
  XP_038438494 (Get FASTA)   NCBI Sequence Viewer  
  XP_038438503 (Get FASTA)   NCBI Sequence Viewer  
  XP_038438511 (Get FASTA)   NCBI Sequence Viewer  
  XP_038438524 (Get FASTA)   NCBI Sequence Viewer  
  XP_038464148 (Get FASTA)   NCBI Sequence Viewer  
  XP_038464149 (Get FASTA)   NCBI Sequence Viewer  
  XP_038464150 (Get FASTA)   NCBI Sequence Viewer  
  XP_038464151 (Get FASTA)   NCBI Sequence Viewer  
  XP_038464152 (Get FASTA)   NCBI Sequence Viewer  
  XP_038464153 (Get FASTA)   NCBI Sequence Viewer  
  XP_038464154 (Get FASTA)   NCBI Sequence Viewer  
  XP_038464155 (Get FASTA)   NCBI Sequence Viewer  
  XP_038464156 (Get FASTA)   NCBI Sequence Viewer  
  XP_038464157 (Get FASTA)   NCBI Sequence Viewer  
  XP_038464158 (Get FASTA)   NCBI Sequence Viewer  
  XP_038528951 (Get FASTA)   NCBI Sequence Viewer  
  XP_038528952 (Get FASTA)   NCBI Sequence Viewer  
  XP_038528953 (Get FASTA)   NCBI Sequence Viewer  
  XP_038528954 (Get FASTA)   NCBI Sequence Viewer  
  XP_038528955 (Get FASTA)   NCBI Sequence Viewer  
  XP_038528956 (Get FASTA)   NCBI Sequence Viewer  
  XP_038528957 (Get FASTA)   NCBI Sequence Viewer  
  XP_038528958 (Get FASTA)   NCBI Sequence Viewer  
  XP_038528959 (Get FASTA)   NCBI Sequence Viewer  
  XP_038528960 (Get FASTA)   NCBI Sequence Viewer  
  XP_038528961 (Get FASTA)   NCBI Sequence Viewer  
  XP_848377 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_848377   ⟸   XM_843284
- Peptide Label: isoform X1
- UniProtKB: F6Y2W8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005623206   ⟸   XM_005623149
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_005623207   ⟸   XM_005623150
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_005623205   ⟸   XM_005623148
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSCAFP00000044134   ⟸   ENSCAFT00000070287
RefSeq Acc Id: ENSCAFP00000056038   ⟸   ENSCAFT00000068646
RefSeq Acc Id: ENSCAFP00000058017   ⟸   ENSCAFT00000091465
RefSeq Acc Id: ENSCAFP00000015730   ⟸   ENSCAFT00000017002
RefSeq Acc Id: XP_038338599   ⟸   XM_038482671
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038338604   ⟸   XM_038482676
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038338608   ⟸   XM_038482680
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038338609   ⟸   XM_038482681
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038338603   ⟸   XM_038482675
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038338602   ⟸   XM_038482674
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038338605   ⟸   XM_038482677
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038338601   ⟸   XM_038482673
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038338600   ⟸   XM_038482672
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038338607   ⟸   XM_038482679
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038338606   ⟸   XM_038482678
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038464148   ⟸   XM_038608220
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038464153   ⟸   XM_038608225
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038464157   ⟸   XM_038608229
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038464158   ⟸   XM_038608230
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038464152   ⟸   XM_038608224
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038464151   ⟸   XM_038608223
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038464154   ⟸   XM_038608226
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038464150   ⟸   XM_038608222
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038464149   ⟸   XM_038608221
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038464156   ⟸   XM_038608228
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038464155   ⟸   XM_038608227
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038528951   ⟸   XM_038673023
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038528956   ⟸   XM_038673028
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038528960   ⟸   XM_038673032
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038528961   ⟸   XM_038673033
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038528955   ⟸   XM_038673027
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038528954   ⟸   XM_038673026
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038528957   ⟸   XM_038673029
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038528953   ⟸   XM_038673025
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038528952   ⟸   XM_038673024
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038528959   ⟸   XM_038673031
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038528958   ⟸   XM_038673030
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038438524   ⟸   XM_038582596
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038438480   ⟸   XM_038582552
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038438494   ⟸   XM_038582566
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038438474   ⟸   XM_038582546
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038438473   ⟸   XM_038582545
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038438511   ⟸   XM_038582583
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038438503   ⟸   XM_038582575
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038400021   ⟸   XM_038544093
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038400026   ⟸   XM_038544098
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038400030   ⟸   XM_038544102
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038400031   ⟸   XM_038544103
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038400025   ⟸   XM_038544097
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038400024   ⟸   XM_038544096
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038400027   ⟸   XM_038544099
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038400023   ⟸   XM_038544095
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038400022   ⟸   XM_038544094
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038400029   ⟸   XM_038544101
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038400028   ⟸   XM_038544100
- Peptide Label: isoform X6
RefSeq Acc Id: ENSCAFP00845025412   ⟸   ENSCAFT00845032499
RefSeq Acc Id: ENSCAFP00845025361   ⟸   ENSCAFT00845032436
RefSeq Acc Id: ENSCAFP00845025471   ⟸   ENSCAFT00845032568
RefSeq Acc Id: ENSCAFP00845025523   ⟸   ENSCAFT00845032636
Protein Domains
NACHT   Pyrin


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000010686 Ensembl
  ENSCAFG00030001707 UniProtKB/TrEMBL
  ENSCAFG00040015669 UniProtKB/TrEMBL
  ENSCAFG00845018347 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00030002709.1 UniProtKB/TrEMBL
  ENSCAFP00030002722.1 UniProtKB/TrEMBL
  ENSCAFP00030002740.1 UniProtKB/TrEMBL
  ENSCAFP00030002759.1 UniProtKB/TrEMBL
  ENSCAFP00040025020 UniProtKB/TrEMBL
  ENSCAFP00040025045 UniProtKB/TrEMBL
  ENSCAFP00040025100 UniProtKB/TrEMBL
  ENSCAFP00040025141 UniProtKB/TrEMBL
  ENSCAFP00845025361 ENTREZGENE
  ENSCAFP00845025361.1 UniProtKB/TrEMBL
  ENSCAFP00845025412 ENTREZGENE
  ENSCAFP00845025412.1 UniProtKB/TrEMBL
  ENSCAFP00845025471.1 UniProtKB/TrEMBL
  ENSCAFP00845025523 ENTREZGENE
  ENSCAFP00845025523.1 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00030003054.1 UniProtKB/TrEMBL
  ENSCAFT00030003067.1 UniProtKB/TrEMBL
  ENSCAFT00030003088.1 UniProtKB/TrEMBL
  ENSCAFT00030003107.1 UniProtKB/TrEMBL
  ENSCAFT00040028810 UniProtKB/TrEMBL
  ENSCAFT00040028834 UniProtKB/TrEMBL
  ENSCAFT00040028900 UniProtKB/TrEMBL
  ENSCAFT00040028944 UniProtKB/TrEMBL
  ENSCAFT00845032436 ENTREZGENE
  ENSCAFT00845032436.1 UniProtKB/TrEMBL
  ENSCAFT00845032499 ENTREZGENE
  ENSCAFT00845032499.1 UniProtKB/TrEMBL
  ENSCAFT00845032568.1 UniProtKB/TrEMBL
  ENSCAFT00845032636 ENTREZGENE
  ENSCAFT00845032636.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.533.10 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/TrEMBL
InterPro DAPIN UniProtKB/TrEMBL
  DEATH-like_dom_sf UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
  NACHT-assoc UniProtKB/TrEMBL
  NACHT_NTPase UniProtKB/TrEMBL
  NLRP_HD2 UniProtKB/TrEMBL
  NOD2_WH UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
NCBI Gene NLRP3 ENTREZGENE
Pfam FISNA UniProtKB/TrEMBL
  LRR_6 UniProtKB/TrEMBL
  NACHT UniProtKB/TrEMBL
  NLRC4_HD2 UniProtKB/TrEMBL
  NOD2_WH UniProtKB/TrEMBL
  PYRIN UniProtKB/TrEMBL
PROSITE DAPIN UniProtKB/TrEMBL
  NACHT UniProtKB/TrEMBL
SMART FISNA UniProtKB/TrEMBL
  PYRIN UniProtKB/TrEMBL
Superfamily-SCOP SSF47986 UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt A0A8C0M1T8_CANLF UniProtKB/TrEMBL
  A0A8C0M351_CANLF UniProtKB/TrEMBL
  A0A8C0SSV5_CANLF UniProtKB/TrEMBL
  A0A8C0YZB5_CANLF UniProtKB/TrEMBL
  A0A8I3NW69_CANLF UniProtKB/TrEMBL
  A0A8I3P020_CANLF UniProtKB/TrEMBL
  A0A8I3P6D8_CANLF UniProtKB/TrEMBL
  A0A8I3PDL7_CANLF UniProtKB/TrEMBL
  F6Y2W8 ENTREZGENE
VGNC ID VGNC:43848 ENTREZGENE