RIN3 (Ras and Rab interactor 3) - Rat Genome Database

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Gene: RIN3 (Ras and Rab interactor 3) Canis lupus familiaris
Analyze
Symbol: RIN3
Name: Ras and Rab interactor 3
RGD ID: 12115840
Description: ENCODES a protein that exhibits GTPase activator activity (inferred); guanyl-nucleotide exchange factor activity (inferred); small GTPase binding (inferred); INVOLVED IN negative regulation of mast cell chemotaxis (ortholog); negative regulation of receptor internalization (ortholog); regulation of vesicle size (ortholog); ASSOCIATED WITH Paget's disease of bone (ortholog); FOUND IN axon (ortholog); cytoplasm (ortholog); cytoplasmic vesicle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.181,733,051 - 1,804,138 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl81,700,161 - 1,803,950 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha81,725,009 - 1,829,175 (+)NCBI
ROS_Cfam_1.081,755,334 - 1,859,544 (+)NCBI
UMICH_Zoey_3.181,693,043 - 1,797,175 (+)NCBI
UNSW_CanFamBas_1.081,660,348 - 1,747,245 (+)NCBI
UU_Cfam_GSD_1.081,770,397 - 1,874,571 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
axon  (IEA,ISO)
cytoplasm  (ISO)
cytoplasmic vesicle  (ISO)
dendrite  (IEA,ISO)
early endosome  (IEA)
endocytic vesicle  (IEA,ISO)
neuronal cell body  (IEA,ISO)
vesicle  (ISO)

Molecular Function

References

Genomics

Comparative Map Data
RIN3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.181,733,051 - 1,804,138 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl81,700,161 - 1,803,950 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha81,725,009 - 1,829,175 (+)NCBI
ROS_Cfam_1.081,755,334 - 1,859,544 (+)NCBI
UMICH_Zoey_3.181,693,043 - 1,797,175 (+)NCBI
UNSW_CanFamBas_1.081,660,348 - 1,747,245 (+)NCBI
UU_Cfam_GSD_1.081,770,397 - 1,874,571 (+)NCBI
RIN3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1492,513,781 - 92,688,994 (+)EnsemblGRCh38hg38GRCh38
GRCh381492,513,773 - 92,688,994 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371492,980,125 - 93,155,339 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361492,049,878 - 92,225,089 (+)NCBINCBI36hg18NCBI36
Build 341492,049,877 - 92,225,085NCBI
Celera1473,032,207 - 73,209,490 (+)NCBI
Cytogenetic Map14q32.12NCBI
HuRef1473,162,292 - 73,338,395 (+)NCBIHuRef
CHM1_11492,918,607 - 93,093,633 (+)NCBICHM1_1
Rin3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912102,248,572 - 102,358,982 (+)NCBIGRCm39mm39
GRCm39 Ensembl12102,249,307 - 102,357,114 (+)Ensembl
GRCm3812102,282,840 - 102,390,854 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12102,283,048 - 102,390,855 (+)EnsemblGRCm38mm10GRCm38
MGSCv3712103,521,284 - 103,629,064 (+)NCBIGRCm37mm9NCBIm37
MGSCv3612102,684,124 - 102,791,901 (+)NCBImm8
Celera12103,500,655 - 103,608,535 (+)NCBICelera
Cytogenetic Map12ENCBI
Rin3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.26121,431,803 - 121,540,957 (+)NCBI
Rnor_6.0 Ensembl6126,170,720 - 126,279,682 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.06126,170,672 - 126,279,682 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.06135,381,785 - 135,490,155 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46126,555,387 - 126,665,098 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.16126,556,517 - 126,668,118 (+)NCBI
Celera6118,920,459 - 119,029,000 (+)NCBICelera
Cytogenetic Map6q32NCBI
Rin3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543814,778,262 - 14,898,747 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543814,777,866 - 14,898,572 (+)NCBIChiLan1.0ChiLan1.0
RIN3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11492,488,770 - 92,662,415 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1492,488,770 - 92,662,415 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01473,148,000 - 73,322,798 (+)NCBIMhudiblu_PPA_v0panPan3
Rin3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864012,701,138 - 12,783,751 (-)NCBI
SpeTri2.0NW_004936733683,309 - 765,897 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RIN3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7114,035,353 - 114,166,543 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.17114,035,137 - 114,166,548 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27120,641,419 - 120,771,254 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RIN3
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12470,261,693 - 70,447,126 (+)NCBI
ChlSab1.1 Ensembl2470,303,459 - 70,450,059 (+)Ensembl
Rin3
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247349,080,109 - 9,197,536 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 4 6 2 8 3
Low 5 5 18 6 6 4 6 12 8 2 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000017468   ⟹   ENSCAFP00000016174
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl81,700,161 - 1,803,950 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000046960   ⟹   ENSCAFP00000040454
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl81,700,161 - 1,803,950 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000070987   ⟹   ENSCAFP00000046044
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl81,700,161 - 1,803,950 (+)Ensembl
RefSeq Acc Id: XM_022422496   ⟹   XP_022278204
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.181,733,051 - 1,804,138 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038482703   ⟹   XP_038338631
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.181,693,043 - 1,797,175 (+)NCBI
RefSeq Acc Id: XM_038482704   ⟹   XP_038338632
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.181,725,146 - 1,797,175 (+)NCBI
RefSeq Acc Id: XM_038544123   ⟹   XP_038400051
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.081,770,397 - 1,874,571 (+)NCBI
RefSeq Acc Id: XM_038544124   ⟹   XP_038400052
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.081,802,516 - 1,874,571 (+)NCBI
RefSeq Acc Id: XM_038582774   ⟹   XP_038438702
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha81,725,009 - 1,829,175 (+)NCBI
RefSeq Acc Id: XM_038582780   ⟹   XP_038438708
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha81,757,138 - 1,829,175 (+)NCBI
RefSeq Acc Id: XM_038608127   ⟹   XP_038464055
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.081,660,348 - 1,747,245 (+)NCBI
RefSeq Acc Id: XM_038673054   ⟹   XP_038528982
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.081,755,334 - 1,859,544 (+)NCBI
RefSeq Acc Id: XM_038673055   ⟹   XP_038528983
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.081,787,462 - 1,859,544 (+)NCBI
Reference Sequences
RefSeq Acc Id: XP_022278204   ⟸   XM_022422496
- Sequence:
RefSeq Acc Id: ENSCAFP00000046044   ⟸   ENSCAFT00000070987
RefSeq Acc Id: ENSCAFP00000016174   ⟸   ENSCAFT00000017468
RefSeq Acc Id: ENSCAFP00000040454   ⟸   ENSCAFT00000046960
RefSeq Acc Id: XP_038338631   ⟸   XM_038482703
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038338632   ⟸   XM_038482704
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038464055   ⟸   XM_038608127
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038528982   ⟸   XM_038673054
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038528983   ⟸   XM_038673055
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038438702   ⟸   XM_038582774
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038438708   ⟸   XM_038582780
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038400051   ⟸   XM_038544123
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038400052   ⟸   XM_038544124
- Peptide Label: isoform X2
Protein Domains
VPS9


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000010958 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00000016174 UniProtKB/TrEMBL
  ENSCAFP00000040454 UniProtKB/TrEMBL
  ENSCAFP00000046044 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000017468 UniProtKB/TrEMBL
  ENSCAFT00000046960 UniProtKB/TrEMBL
  ENSCAFT00000070987 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1050.80 UniProtKB/TrEMBL
  3.30.505.10 UniProtKB/TrEMBL
InterPro SH2 UniProtKB/TrEMBL
  SH2_dom_sf UniProtKB/TrEMBL
  VPS9 UniProtKB/TrEMBL
  VPS9_dom_sf UniProtKB/TrEMBL
NCBI Gene RIN3 ENTREZGENE
Pfam VPS9 UniProtKB/TrEMBL
PROSITE SH2 UniProtKB/TrEMBL
  VPS9 UniProtKB/TrEMBL
SMART SH2 UniProtKB/TrEMBL
  VPS9 UniProtKB/TrEMBL
Superfamily-SCOP SSF109993 UniProtKB/TrEMBL
  SSF55550 UniProtKB/TrEMBL
UniProt A0A5F4BZ35_CANLF UniProtKB/TrEMBL
  F1Q2X0_CANLF UniProtKB/TrEMBL
  J9P4H5_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:45588 ENTREZGENE