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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Bronchial Neoplasms
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Accession:DOID:9001241 term browser browse the term
Definition:Tumors or cancer of the BRONCHI.
Synonyms:exact_synonym: bronchial neoplasm;   bronchial neoplasms;   bronchus neoplasm;   neoplasm of bronchus
 primary_id: MESH:D001984
For additional species annotation, visit the Alliance of Genome Resources.



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bronchiolo-alveolar adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnd1 cyclin D1 ISO protein:increased expression:lung RGD PMID:14674039 RGD:13434930 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Dnmt1 DNA methyltransferase 1 disease_progression ISO RGD PMID:19484794 RGD:4140940 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
JBrowse link
G Egfr epidermal growth factor receptor ISO
IMP
DNA:snp:cds:p.T790M (human)
DNA:mutations:exons:
protein:increased expression:tumor (human)
RGD PMID:15737014 PMID:26059825 PMID:21419590 RGD:5131465, RGD:11075076, RGD:5131630 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Egr1 early growth response 1 ISO mRNA:decreased expression:tumor (human) RGD PMID:11948124 RGD:5131942 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Gstp1 glutathione S-transferase pi 1 ISO DNA:hypermethylation:promoter (human) RGD PMID:19484794 RGD:4140940 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Kras KRAS proto-oncogene, GTPase IMP DNA:mutations:cds: RGD PMID:26059825 RGD:11075076 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Mir130a microRNA 130a ISO CTD Direct Evidence: marker/mechanism CTD PMID:25926378 NCBI chr 3:69,822,542...69,822,629
Ensembl chr 3:69,822,542...69,822,629
JBrowse link
G Mir144 microRNA 144 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25926378 NCBI chr10:62,961,348...62,961,430
Ensembl chr10:62,961,348...62,961,430
JBrowse link
G Mir19a microRNA 19a ISO CTD Direct Evidence: marker/mechanism CTD PMID:25926378 NCBI chr15:92,180,912...92,180,993
Ensembl chr15:92,180,912...92,180,993
JBrowse link
G Mir345 microRNA 345 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25926378 NCBI chr 6:127,754,027...127,754,122
Ensembl chr 6:127,754,027...127,754,122
JBrowse link
G Mir497 microRNA 497 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25926378 NCBI chr10:54,951,514...54,951,582
Ensembl chr10:54,951,505...54,951,584
JBrowse link
G Tp53 tumor protein p53 IMP DNA:mutations:exons: RGD PMID:26059825 RGD:11075076 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
bronchus carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gstp1 glutathione S-transferase pi 1 ISO mRNA:decreased expression:bronchus, epithelial cell RGD PMID:10749130 RGD:4142527 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO protein:increased secretion:lung (human) RGD PMID:18764914 RGD:4145523 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Il10 interleukin 10 ISO protein:increased expression:lung RGD PMID:8030748 RGD:4143231 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO protein:increased expression, alternative forms:lung RGD PMID:8030748 RGD:4143231 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
JBrowse link
large cell neuroendocrine carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc7a5 solute carrier family 7 member 5 disease_progression ISO RGD PMID:18440724 RGD:151361285 NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823
JBrowse link
lung adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
JBrowse link
G Abce1 ATP binding cassette subfamily E member 1 severity ISO mRNA, protein:increased expression:lung (human) RGD PMID:18788636 RGD:11046260 NCBI chr19:28,205,566...28,230,489
Ensembl chr19:28,205,555...28,230,489
JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr  X:105,942,794...106,006,573
Ensembl chr  X:105,942,799...106,006,427
JBrowse link
G Adam28 ADAM metallopeptidase domain 28 exacerbates
disease_progression
treatment
ISO protein:increased expression:lung RGD PMID:29882245 PMID:26800504 PMID:30190423 PMID:20112342 RGD:153297792, RGD:11531771, RGD:153297795, RGD:153297794 NCBI chr15:43,774,463...43,840,726
Ensembl chr15:42,944,467...43,840,672
JBrowse link
G Ahcy adenosylhomocysteinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 3:143,569,134...143,584,359
Ensembl chr 3:143,569,094...143,584,393
JBrowse link
G Ahr aryl hydrocarbon receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:12597446 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 disease_progression ISO RGD PMID:30727821 RGD:27226687 NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674
JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO ClinVar Annotator: match by term: Adenocarcinoma of lung ClinVar PMID:17611497 PMID:18256540 PMID:18392055 PMID:18504432 PMID:18611285 More... NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Alb albumin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:239,375,657...239,407,967
Ensembl chr 1:239,375,669...239,407,890
JBrowse link
G Aldoa aldolase, fructose-bisphosphate A ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182
JBrowse link
G Alk ALK receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Lung adenocarcinoma
CTD
ClinVar
PMID:18923525 PMID:20979469 PMID:20979473 PMID:21030459 PMID:21575866 More... NCBI chr 6:22,879,653...23,599,636
Ensembl chr 6:22,880,625...23,598,034
JBrowse link
G Alox12b arachidonate 12-lipoxygenase, 12R type ISO CTD Direct Evidence: marker/mechanism CTD PMID:30258081 NCBI chr10:53,863,060...53,874,938
Ensembl chr10:53,863,060...53,874,938
JBrowse link
G Alox5 arachidonate 5-lipoxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:30258081 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
JBrowse link
G Anapc2 anaphase promoting complex subunit 2 severity ISO mRNA:decreased expression:lung (human) RGD PMID:12036940 RGD:14696682 NCBI chr 3:8,086,434...8,098,182
Ensembl chr 3:8,086,462...8,098,178
JBrowse link
G Anp32a acidic nuclear phosphoprotein 32 family member A ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 Ensembl chr 8:62,827,456...62,865,443 JBrowse link
G Anxa1 annexin A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
JBrowse link
G Anxa5 annexin A5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369
JBrowse link
G Apc APC regulator of WNT signaling pathway ISO ClinVar Annotator: match by term: Adenocarcinoma of lung ClinVar PMID:1316610 PMID:1338764 PMID:2281069 PMID:8187091 PMID:8381579 More... NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785
JBrowse link
G Apoa1 apolipoprotein A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Aqp4 aquaporin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856
JBrowse link
G Araf A-Raf proto-oncogene, serine/threonine kinase ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:24569458 PMID:26619011 NCBI chr  X:1,227,392...1,292,356
Ensembl chr  X:1,227,392...1,239,073
JBrowse link
G Arg1 arginase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
JBrowse link
G Arhgap35 Rho GTPase activating protein 35 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr 1:77,202,436...77,319,298
Ensembl chr 1:77,202,436...77,319,298
JBrowse link
G Atp5pd ATP synthase peripheral stalk subunit d ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr10:100,657,700...100,662,960
Ensembl chr10:100,657,708...100,663,479
JBrowse link
G Atrx ATRX, chromatin remodeler disease_progression ISO RGD PMID:31374064 RGD:127285382 NCBI chr  X:70,850,981...70,997,330
Ensembl chr  X:70,850,981...70,997,330
JBrowse link
G Axin2 axin 2 susceptibility
disease_progression
ISO DNA:SNP:cds:p.P50S(human)
DNA:SNPs::1712 +19 G>A,148 C>T(human)
RGD PMID:16820935 PMID:30346805 RGD:151356657, RGD:151356655 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231
JBrowse link
G B2m beta-2 microglobulin ISO ClinVar Annotator: match by term: Adenocarcinoma of lung ClinVar PMID:26619011 NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766
JBrowse link
G Bap1 Brca1 associated protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231345 NCBI chr16:6,446,709...6,455,535
Ensembl chr16:6,446,709...6,455,535
JBrowse link
G Bhlhe41 basic helix-loop-helix family, member e41 ISO mRNA:decreased expression:lung (human) RGD PMID:18223678 RGD:151665316 NCBI chr 4:178,833,085...178,838,685
Ensembl chr 4:178,834,271...178,838,468
JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma
CTD
ClinVar
PMID:12068308 PMID:12198537 PMID:12447372 PMID:12460918 PMID:12460919 More... NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463
JBrowse link
G Btk Bruton tyrosine kinase exacerbates
susceptibility
ISO mRNA:decreased expression:lung (human) RGD PMID:31803536 PMID:32351880 RGD:151347849, RGD:151347848 NCBI chr  X:97,722,796...97,762,315
Ensembl chr  X:97,722,802...97,761,853
JBrowse link
G Bzw2 basic leucine zipper and W2 domains 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 6:52,828,069...52,888,599
Ensembl chr 6:52,827,661...52,888,628
JBrowse link
G Cadm1 cell adhesion molecule 1 IEP DNA, mRNA:hypermethylation, decreased expression:promoter:liver RGD PMID:16814249 RGD:2289096 NCBI chr 8:47,847,836...48,178,703
Ensembl chr 8:47,847,325...48,182,833
JBrowse link
G Calr calreticulin treatment ISO human cells and recombinant gene in a mouse model RGD PMID:18245558 RGD:150521698 NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414
JBrowse link
G Capg capping actin protein, gelsolin like ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr 4:104,594,743...104,611,856
Ensembl chr 4:104,594,753...104,611,856
JBrowse link
G Cbx5 chromobox 5 disease_progression ISO mRNA,protein:increased expression:lung: RGD PMID:22900142 RGD:9586743 NCBI chr 7:134,333,165...134,376,102
Ensembl chr 7:134,331,335...134,375,022
JBrowse link
G Cbx7 chromobox 7 ISO mRNA,DNA:decreased expression, loss of heterozygosity:lung: RGD PMID:22214847 RGD:9587356 NCBI chr 7:111,460,656...111,479,231
Ensembl chr 7:111,460,656...111,477,973
JBrowse link
G Ccnd1 cyclin D1 disease_progression
treatment
ISO RGD PMID:26681199 PMID:19355812 RGD:11536846, RGD:13434927 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccnd2 cyclin D2 disease_progression ISO RGD PMID:30308939 RGD:151665105 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 2:82,591,750...82,602,903
Ensembl chr 2:82,590,630...82,602,930
JBrowse link
G Cd44 CD44 molecule (Indian blood group) disease_progression ISO mRNA:splice variants:lung
mRNA:increased expression:lung (human)
RGD PMID:18091389 PMID:29537891 RGD:2289345, RGD:149735539 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cdc73 cell division cycle 73 exacerbates ISO mRNA:decreased expression:lung (human) RGD PMID:21692036 RGD:150537041 NCBI chr13:55,357,226...55,449,690
Ensembl chr13:55,357,226...55,449,656
JBrowse link
G Cdh1 cadherin 1 IDA DNA:increased methylation RGD PMID:16329148 RGD:1599556 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdk12 cyclin-dependent kinase 12 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar NCBI chr10:83,201,177...83,256,906
NCBI chr10:83,267,332...83,280,881
Ensembl chr10:83,201,211...83,280,888
JBrowse link
G Cdk4 cyclin-dependent kinase 4 ISO protein:increased expression:lung
ClinVar Annotator: match by term: Lung adenocarcinoma
ClinVar
RGD
PMID:5377176 PMID:7652577 PMID:8528263 PMID:8968104 PMID:9228064 More... RGD:13464277 NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Cdk6 cyclin-dependent kinase 6 ISO protein:increased expression:lung RGD PMID:10574260 RGD:13464325 NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A ISO ClinVar Annotator: match by term: Adenocarcinoma of lung ClinVar PMID:7780957 PMID:8521414 PMID:9324288 PMID:10491434 PMID:16234564 More... NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit susceptibility ISO mRNA,protein:decreased expression:lung
DNA:SNPs:multiples:multiples (human)
protein:increased expression:lung
DNA:SNP: :rs8042374(human)
associated with smoking; DNA:SNP: :rs1051730(human)
RGD PMID:19223495 PMID:25233467 PMID:24686516 PMID:24686516 PMID:20554942 RGD:150524354, RGD:151347535, RGD:151347530, RGD:151347530, RGD:150527848 NCBI chr 8:55,401,981...55,415,012
Ensembl chr 8:55,401,702...55,415,165
JBrowse link
G Chrna5 cholinergic receptor nicotinic alpha 5 subunit susceptibility
disease_progression
ISO DNA:SNP:cds: p.D398N (rs1696996)(human)
mRNA:increased expression:lung
DNA:SNP: :rs503464(human)
associated with smoking; DNA:SNPs: :rs2036527, rs684513, rs667282(human)
DNA:SNP:cds: p.D398N(human)
RGD PMID:19223495 PMID:20124469 PMID:23314339 PMID:20554942 PMID:19577767 More... RGD:150524354, RGD:150527851, RGD:150527849, RGD:150527848, RGD:150524359, RGD:150524356 NCBI chr 8:55,369,794...55,398,526
Ensembl chr 8:55,369,794...55,398,146
JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit ISO mRNA:increased expression:lung
DNA:hypomethylation:promoter:
RGD PMID:20124469 PMID:22945651 RGD:150527851, RGD:151361154 NCBI chr 8:55,418,379...55,436,967
Ensembl chr 8:55,418,313...55,437,027
JBrowse link
G Clptm1l CLPTM1-like susceptibility
no_association
ameliorates
ISO CTD Direct Evidence: marker/mechanism
DNA:SNP: :rs401681(human)
DNA:SNP::rs77518573(human)
DNA:SNP:: rs4975616(human)
DNA:SNP::rs401681(human)
DNA:SNP:: rs31490(human)
mRNA:increased expression:lung
CTD
RGD
PMID:22675468 PMID:24386361 PMID:31935503 PMID:19955392 PMID:24861918 More... RGD:150537098, RGD:150530635, RGD:150530502, RGD:150530499, RGD:150530498, RGD:150530485, RGD:150530483, RGD:150530483 NCBI chr 1:29,667,545...29,683,530
Ensembl chr 1:29,667,545...29,683,530
JBrowse link
G Cmtr2 cap methyltransferase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr19:38,190,718...38,197,549
Ensembl chr19:38,190,642...38,197,804
JBrowse link
G Col10a1 collagen type X alpha 1 chain disease_progression ISO mRNA:increased expression:lung RGD PMID:33324550 PMID:33324550 RGD:150429752, RGD:150429752 NCBI chr20:38,183,103...38,189,488
Ensembl chr20:38,182,494...38,189,494
JBrowse link
G Crebbp CREB binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888
JBrowse link
G Csf1r colony stimulating factor 1 receptor ISO protein:increased expression:lung (human) RGD PMID:23702648 RGD:150524280 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
JBrowse link
G Csrp3 cysteine and glycine rich protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:98,528,067...98,546,647
Ensembl chr 1:98,528,068...98,546,653
JBrowse link
G Ctnnb1 catenin beta 1 ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:9065402 PMID:9065403 PMID:9294210 PMID:9500465 PMID:9927029 More... NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 exacerbates ISO protein:increased expression:lung (human)
mRNA:increased expression:lung (human)
RGD PMID:30103827 PMID:19716197 RGD:152023735, RGD:152177480 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 ISO protein:increased expression:lung (human) RGD PMID:19358281 RGD:152177688 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 ameliorates ISO DNA:hypomethylation:promoter (human)
mRNA:decreased expression:lung (human)
human cell line in a mouse model
RGD PMID:24736069 PMID:25519225 PMID:27793774 RGD:151361181, RGD:151665499, RGD:151665173 NCBI chr 3:159,275,947...159,290,383
Ensembl chr 3:159,275,947...159,290,383
JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18669584 NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887
JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26206333 NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:21067377 PMID:21518476 PMID:22160010 PMID:22744846 PMID:22898539 More... NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta susceptibility ISO DNA:SNPs,haplotype:promoter:-283T >C,-579G>T(human) RGD PMID:15528220 RGD:9589086 NCBI chr 3:142,130,592...142,169,124
Ensembl chr 3:142,130,592...142,169,124
JBrowse link
G Dok1 docking protein 1 disease_progression ISO RGD PMID:20139980 RGD:152177521 NCBI chr 4:115,537,453...115,540,464
Ensembl chr 4:115,537,462...115,540,465
JBrowse link
G Dok2 docking protein 2 disease_progression
exacerbates
ISO mRNA:decreased expression:lung (human) RGD PMID:20139980 PMID:30475228 PMID:20139980 PMID:24255704 RGD:152177521, RGD:152177492, RGD:152177521, RGD:152177493 NCBI chr15:45,826,984...45,841,409
Ensembl chr15:45,827,398...45,841,402
JBrowse link
G Dok3 docking protein 3 disease_progression ISO RGD PMID:20139980 RGD:152177521 NCBI chr17:9,109,633...9,115,188
Ensembl chr17:9,109,597...9,115,188
JBrowse link
G Dot1l DOT1 like histone lysine methyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr 7:8,917,786...8,959,474
Ensembl chr 7:8,917,786...8,956,475
JBrowse link
G E2f1 E2F transcription factor 1 ISO mRNA:increased expression:lung RGD PMID:26695082 RGD:13464334 NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361
JBrowse link
G E2f3 E2F transcription factor 3 ISO RGD PMID:16938365 RGD:13464341 NCBI chr17:34,601,756...34,679,139
Ensembl chr17:34,601,830...34,676,253
JBrowse link
G Eef2 eukaryotic translation elongation factor 2 exacerbates ISO protein:increased expression:lung (human) RGD PMID:21554491 RGD:153298904 NCBI chr 7:8,533,248...8,538,518
Ensembl chr 7:8,533,116...8,559,183
JBrowse link
G Eef2k eukaryotic elongation factor-2 kinase ameliorates ISO Human cells in mouse model RGD PMID:30522114 RGD:153298964 NCBI chr 1:175,393,119...175,454,452
Ensembl chr 1:175,393,154...175,455,164
JBrowse link
G Egf epidermal growth factor ISO DNA:polymorphism: :p.A61G (human) RGD PMID:26625757 RGD:11538684 NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Egfr epidermal growth factor receptor disease_progression ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma
CTD
ClinVar
RGD
PMID:2302402 PMID:15118073 PMID:15118125 PMID:15329413 PMID:15710947 More... RGD:126790475 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 disease_progression ISO RGD PMID:20940408 RGD:9589170 NCBI chr20:3,919,623...3,936,751
Ensembl chr20:3,919,624...3,941,547
JBrowse link
G Eif2b1 eukaryotic translation initiation factor 2B subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr12:32,025,593...32,033,848
Ensembl chr12:32,025,557...32,046,601
JBrowse link
G Eif2b4 eukaryotic translation initiation factor 2B subunit delta ISO CTD Direct Evidence: marker/mechanism CTD PMID:24366584 NCBI chr 6:25,183,177...25,188,832
Ensembl chr 6:25,183,186...25,188,829
JBrowse link
G Eif2b5 eukaryotic translation initiation factor 2B subunit epsilon ISO CTD Direct Evidence: marker/mechanism CTD PMID:24366584 NCBI chr11:80,394,433...80,404,468
Ensembl chr11:80,394,433...80,404,419
JBrowse link
G Eif3e eukaryotic translation initiation factor 3 subunit E ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 7:74,339,848...74,372,483
Ensembl chr 7:74,339,828...74,373,096
JBrowse link
G Eml4 EMAP like 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22980554 PMID:22999080 NCBI chr 6:11,219,545...11,334,824
Ensembl chr 6:11,219,566...11,334,879
JBrowse link
G Eno1 enolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 PMID:27602772 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
JBrowse link
G Ep300 E1A binding protein p300 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088
JBrowse link
G Epha5 EPH receptor A5 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:16140923 NCBI chr14:23,653,393...24,020,135
Ensembl chr14:23,653,393...24,017,317
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 disease_progression ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar
RGD
PMID:15457249 PMID:22908275 PMID:24033266 PMID:26619011 PMID:26824984 RGD:126790475 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 disease_progression ISO RGD PMID:26824984 RGD:126790475 NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525
JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 disease_progression ISO RGD PMID:26824984 RGD:126790475 NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595
JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:21327329 NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963
JBrowse link
G Erp29 endoplasmic reticulum protein 29 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit disease_progression ISO RGD PMID:24097870 RGD:126781716 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362
JBrowse link
G Fas Fas cell surface death receptor ISO mRNA:decreased expression:lung (human) RGD PMID:29254206 RGD:151665107 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Fasn fatty acid synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fbl fibrillarin ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:83,469,832...83,478,932
Ensembl chr 1:83,469,832...83,478,932
JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 ISO ClinVar Annotator: match by term: Adenocarcinoma of lung ClinVar PMID:26619011 NCBI chr 2:170,150,552...170,310,698
Ensembl chr 2:170,149,694...170,309,941
JBrowse link
G Fgf18 fibroblast growth factor 18 ISO mRNA:decreased expression:lung (human) RGD PMID:19296538 RGD:150429981 NCBI chr10:17,706,011...17,737,702
Ensembl chr10:17,706,174...17,736,818
JBrowse link
G Fgf9 fibroblast growth factor 9 disease_progression ISO protein:increased expression:lung (human)
mRNA:decreased expression:lung (human)
RGD PMID:19296538 PMID:19358281 PMID:20464547 RGD:150429981 RGD:152177688, RGD:152975620 NCBI chr15:32,208,993...32,254,952
Ensembl chr15:32,210,074...32,253,309
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:17525745 PMID:18552176 PMID:22238366 PMID:23002168 PMID:23908597 More... NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 ISO ClinVar Annotator: match by term: Adenocarcinoma of lung ClinVar PMID:1908846 PMID:7773297 PMID:8858131 PMID:9677066 PMID:10073901 More... NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341
JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 disease_progression
exacerbates
ISO DNA:SNP:exon 9: p.G288R (human)
DNA:SNP:exon 9: p.G388R (rs351855)(human)
human cells in mouse model
RGD PMID:16061909 PMID:19296538 PMID:29402970 RGD:150429976, RGD:150429981, RGD:150429984 NCBI chr17:9,461,541...9,476,268
Ensembl chr17:9,461,547...9,476,242
JBrowse link
G Fkbp11 FKBP prolyl isomerase 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 7:129,871,870...129,877,760
Ensembl chr 7:129,871,870...129,875,303
JBrowse link
G Foxa1 forkhead box A1 ISO mRNA:increased expression:lung
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:34254728 PMID:12234996 PMID:29072684 RGD:151665758, RGD:151665822 NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188
JBrowse link
G Foxo3 forkhead box O3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19380174 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
JBrowse link
G Foxp1 forkhead box P1 IEP mRNA:decreased expression:lung (rat) RGD PMID:16023287 RGD:11561933 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258
JBrowse link
G Frzb frizzled-related protein severity ISO mRNA:decreased expression:lung (human) RGD PMID:27623992 RGD:32716395 NCBI chr 3:65,332,274...65,365,208
Ensembl chr 3:65,332,277...65,365,208
JBrowse link
G Fubp1 far upstream element binding protein 1 ISO mRNA:decreased expression:lung (human) RGD PMID:32481602 RGD:151361197 NCBI chr 2:241,159,481...241,186,591
Ensembl chr 2:241,159,512...241,186,602
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
JBrowse link
G Gar1 GAR1 ribonucleoprotein ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 2:218,375,231...218,382,509
Ensembl chr 2:218,375,353...218,382,524
JBrowse link
G Gart phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr11:30,864,896...30,891,125
Ensembl chr11:30,865,889...30,891,125
JBrowse link
G Gjb2 gap junction protein, beta 2 IDA DNA, mRNA:hypermethylation, decreased expression:lung RGD PMID:16637067 RGD:11568669 NCBI chr15:31,260,390...31,278,222
Ensembl chr15:31,260,357...31,278,177
JBrowse link
G Gnas GNAS complex locus ISO ClinVar Annotator: match by term: Adenocarcinoma of lung ClinVar PMID:1517386 PMID:1594625 PMID:1944469 PMID:2549426 PMID:3720010 More... NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262
JBrowse link
G Gng11 G protein subunit gamma 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24366584 NCBI chr 4:32,023,003...32,028,443
Ensembl chr 4:32,023,003...32,028,442
JBrowse link
G Gnpnat1 glucosamine-phosphate N-acetyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr15:18,596,180...18,608,854
Ensembl chr15:18,596,442...18,608,739
JBrowse link
G Golm1 golgi membrane protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr17:4,995,925...5,044,329
Ensembl chr17:4,996,104...5,034,057
JBrowse link
G Gpi glucose-6-phosphate isomerase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:86,828,211...86,856,077
Ensembl chr 1:86,828,216...86,856,086
JBrowse link
G Gpx3 glutathione peroxidase 3 ISO mRNA:decreased expression:lung (human) RGD PMID:23374247 RGD:151708716 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035
JBrowse link
G Grwd1 glutamate-rich WD repeat containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:96,301,260...96,306,962
Ensembl chr 1:96,301,261...96,307,201
JBrowse link
G H1f10 H1.10 linker histone ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 4:120,440,515...120,444,705
Ensembl chr 4:120,440,870...120,441,448
JBrowse link
G Hells helicase, lymphoid specific ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:236,701,704...236,748,239
Ensembl chr 1:236,701,758...236,746,844
JBrowse link
G Hk1 hexokinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr20:30,230,488...30,332,161
Ensembl chr20:30,230,486...30,332,131
JBrowse link
G Hk2 hexokinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530
JBrowse link
G Hmgb2 high mobility group box 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24366584 PMID:27602772 NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140
JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 7:134,375,318...134,381,610
Ensembl chr 7:134,375,150...134,381,609
JBrowse link
G Hoxb7 homeo box B7 severity ISO protein:increased expression:lung epithelium (human) RGD PMID:22911672 RGD:10402176 NCBI chr10:81,252,616...81,256,034
Ensembl chr10:81,252,553...81,256,034
JBrowse link
G Hras HRas proto-oncogene, GTPase ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma
CTD
ClinVar
PMID:1904555 PMID:3510078 PMID:11150980 PMID:12835555 PMID:16155195 More... NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
JBrowse link
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr  X:21,089,152...21,091,597
Ensembl chr  X:21,089,122...21,109,488
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
JBrowse link
G Htra1 HtrA serine peptidase 1 disease_progression ISO human cells in mouse model RGD PMID:24356998 RGD:152975621 NCBI chr 1:185,497,815...185,547,380
Ensembl chr 1:185,497,735...185,547,379
JBrowse link
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 disease_progression ISO mRNA:increased expression:lung (human)
ClinVar Annotator: match by term: Adenocarcinoma of lung
protein:increased expression:blood plasma (human)
ClinVar
RGD
PMID:18772396 PMID:19657110 PMID:19798509 PMID:19818334 PMID:20946881 More... RGD:149735539, RGD:149735540 NCBI chr 9:66,534,146...66,563,703
Ensembl chr 9:66,534,146...66,563,708
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 severity ISO protein:increased expression:lung (human)
protein:increased expression:blood serum (human)
RGD PMID:30128035 PMID:29465809 RGD:149735564, RGD:149735567 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
JBrowse link
G Igf2r insulin-like growth factor 2 receptor IAGP mRNA:deletions: :c.3698_4902del, c.3366_4902del, c.3817_4697del (rat) RGD PMID:12503077 RGD:1298968 NCBI chr 1:47,979,109...48,067,501
Ensembl chr 1:47,979,109...48,067,501
JBrowse link
G Ikzf1 IKAROS family zinc finger 1 exacerbates
ameliorates
ISO protein:increased expression:lung (human)
mRNA:increased expression:lung (human)
RGD PMID:33738286 PMID:32787735 RGD:151347632, RGD:150540324 NCBI chr14:86,255,065...86,340,839
Ensembl chr14:86,255,065...86,342,416
JBrowse link
G Il1r2 interleukin 1 receptor type 2 disease_progression
severity
ISO mRNA:altered expression:lung (human)
mRNA:increased expression:lung (human)
RGD PMID:31921619 PMID:29942094 RGD:152998982, RGD:152998998 NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725
JBrowse link
G Impdh2 inosine monophosphate dehydrogenase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 8:109,256,705...109,261,365
Ensembl chr 8:109,256,728...109,261,359
JBrowse link
G Ipo4 importin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr15:29,117,365...29,127,382
Ensembl chr15:29,117,365...29,127,285
JBrowse link
G Ipo5 importin 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr15:97,990,755...98,041,074
Ensembl chr15:98,005,299...98,041,126
JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 ISO mRNA:increased expression:lung (human) RGD PMID:21278795 RGD:36049796 NCBI chr 7:55,653,949...55,714,371
Ensembl chr 7:55,653,962...55,713,121
JBrowse link
G Jak2 Janus kinase 2 treatment ISO human cells in mouse model RGD PMID:27025877 RGD:11574134 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:24366584 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
JBrowse link
G Kcnj4 potassium inwardly-rectifying channel, subfamily J, member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30512237 NCBI chr 7:111,047,097...111,074,151
Ensembl chr 7:111,047,094...111,074,151
JBrowse link
G Klf5 Kruppel-like factor 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr15:76,060,320...76,079,445
Ensembl chr15:76,064,258...76,079,445
JBrowse link
G Kmt2c lysine methyltransferase 2C disease_progression
onset
ISO RGD PMID:32867667 PMID:30821106 RGD:151356760, RGD:151356761 NCBI chr 4:9,620,638...9,834,787
Ensembl chr 4:9,609,627...9,833,539
JBrowse link
G Kpna2 karyopherin subunit alpha 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr10:91,933,951...91,946,115
Ensembl chr10:91,933,951...91,946,150
JBrowse link
G Kras KRAS proto-oncogene, GTPase ISO DNA:point mutation:CDS:p.G12C (human)
ClinVar Annotator: match by term: Adenocarcinoma of lung
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
RGD
PMID:2278970 PMID:3122217 PMID:6320174 PMID:8143615 PMID:8425762 More... RGD:1600465 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Ldha lactate dehydrogenase A ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472
JBrowse link
G Lmna lamin A/C ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423
JBrowse link
G Lmnb1 lamin B1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr18:50,175,861...50,215,210
Ensembl chr18:50,175,874...50,214,502
JBrowse link
G Lrp1b LDL receptor related protein 1B disease_progression ISO DNA:mutations:multiple: (human) RGD PMID:18948947 RGD:11064706 NCBI chr 3:24,594,302...26,715,037
Ensembl chr 3:24,594,991...26,715,505
JBrowse link
G Lrrc56 leucine rich repeat containing 56 ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:1904555 PMID:3510078 PMID:11150980 PMID:12835555 PMID:16155195 More... NCBI chr 1:196,299,843...196,315,170
Ensembl chr 1:196,299,846...196,315,172
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma
mRNA:increased expression:lung (human)
CTD
ClinVar
RGD
PMID:18632602 PMID:21383288 PMID:22135231 PMID:22197931 PMID:22588879 More... RGD:151665107 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 severity ISO RGD PMID:21896780 PMID:12231543 RGD:150429783, RGD:150429821 NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993
JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 exacerbates ISO RGD PMID:23533274 RGD:151356978 NCBI chr17:53,382,908...53,403,216
Ensembl chr17:53,383,131...53,403,216
JBrowse link
G Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 ameliorates
exacerbates
ISO human cell line in a mouse model
mRNA, protein:increased expression:lung (human)
RGD PMID:22824148 PMID:28306189 PMID:33510968 RGD:151347677, RGD:151347678, RGD:151347681 NCBI chr 9:42,200,708...42,326,708
Ensembl chr 9:42,200,278...42,326,698
JBrowse link
G Mapk14 mitogen activated protein kinase 14 exacerbates ISO mRNA:increased expression:lung (human) RGD PMID:31969449 RGD:151665505 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member severity
treatment
ISO mRNA:increased expression:lung (human)
human cells in mouse model
RGD PMID:31200834 PMID:31200834 RGD:151356911, RGD:151356911 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Mir127 microRNA 127 treatment ISO Human cells in mouse model RGD PMID:27869168 RGD:152995353 NCBI chr 6:128,546,215...128,546,311
Ensembl chr 6:128,546,215...128,546,311
JBrowse link
G Mir154 microRNA 154 ISO associated with nicotine dependence; RNA:decreased expression:blood serum (human) RGD PMID:25386559 RGD:152995475 NCBI chr 6:128,752,947...128,753,030
Ensembl chr 6:128,752,947...128,753,030
JBrowse link
G Mir20a microRNA 20a ISO RGD PMID:26560875 RGD:11572141 NCBI chr15:92,181,084...92,181,168
Ensembl chr15:92,181,084...92,181,168
JBrowse link
G Mir21 microRNA 21 disease_progression ISO RNA:increased expression:lung (human)
miRNA:increased expression:sputum (human)
RGD PMID:29892003 PMID:27777637 RGD:152998892, RGD:152998954 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
JBrowse link
G Mir31 microRNA 31 severity
disease_progression
ISO RNA:increased expression:lung (human) RGD PMID:26657862 PMID:29367106 PMID:23946296 PMID:27215092 RGD:11343268, RGD:152998945, RGD:152998944, RGD:11250998 NCBI chr 5:103,599,038...103,599,143 JBrowse link
G Mki67 marker of proliferation Ki-67 disease_progression ISO protein:altered expression:lung (human) RGD PMID:26942465 RGD:152999419 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Mlh1 mutL homolog 1 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:15340264 PMID:17510385 PMID:18307539 PMID:19419416 PMID:22136435 More... NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617
JBrowse link
G Mre11 MRE11 homolog, double strand break repair nuclease ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 8:11,618,876...11,680,451
Ensembl chr 8:11,632,354...11,678,279
JBrowse link
G Mrpl12 mitochondrial ribosomal protein L12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr10:105,758,410...105,762,913
Ensembl chr10:105,758,410...105,762,913
JBrowse link
G Mrps5 mitochondrial ribosomal protein S5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 3:114,821,046...114,837,291
Ensembl chr 3:114,821,046...114,837,291
JBrowse link
G Ms4a1 membrane spanning 4-domains A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22514692 NCBI chr 1:207,906,370...207,927,028
Ensembl chr 1:207,906,374...207,918,512
JBrowse link
G Msh2 mutS homolog 2 no_association ISO DNA:polymorphisms:introns:IVS10+12A>G, IVS12-6T>C (human)
DNA:polymorphisms:promoter, intron:-118T>C, IVS1+9G>C (human)
RGD PMID:16614121 PMID:16614121 RGD:11065547, RGD:11065547 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938
JBrowse link
G Msh3 mutS homolog 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21327329 NCBI chr 2:23,444,326...23,585,777 JBrowse link
G Msh6 mutS homolog 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21327329 NCBI chr 6:6,562,631...6,579,995
Ensembl chr 6:6,562,632...6,579,956
JBrowse link
G Muc1 mucin 1, cell surface associated ISO mRNA:increased expression:lung RGD PMID:8694545 RGD:5131260 NCBI chr 2:174,635,559...174,640,738
Ensembl chr 2:174,635,995...174,640,733
JBrowse link
G Muc4 mucin 4, cell surface associated disease_progression ISO protein:increased expression:trachea RGD PMID:17126950 RGD:5131208 NCBI chr11:68,008,245...68,053,229 JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor ISO human cell line in mouse model
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Lung adenocarcinoma
CTD
ClinVar
RGD
PMID:25157968 PMID:26619011 PMID:26656844 PMID:27602772 PMID:20033209 RGD:7207787 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor treatment
ameliorates
ISO mouse cell line in a mouse model RGD PMID:32140881 PMID:30712876 RGD:150520172, RGD:150540309 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
JBrowse link
G Naa10 N(alpha)-acetyltransferase 10, NatA catalytic subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr  X:151,656,056...151,661,304
Ensembl chr  X:151,656,056...151,661,252
JBrowse link
G Ncapg non-SMC condensin I complex, subunit G ISO CTD Direct Evidence: marker/mechanism CTD PMID:34419073 NCBI chr14:65,404,235...65,432,902
Ensembl chr14:65,404,163...65,432,902
JBrowse link
G Ncl nucleolin ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 9:86,999,588...87,008,112
Ensembl chr 9:86,998,019...87,008,136
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:26619011 PMID:29018201 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nop56 NOP56 ribonucleoprotein ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 3:117,476,963...117,481,847
Ensembl chr 3:117,477,053...117,481,841
JBrowse link
G Nop58 NOP58 ribonucleoprotein ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 9:61,120,939...61,144,810
Ensembl chr 9:61,120,929...61,144,810
JBrowse link
G Npm1 nucleophosmin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645
JBrowse link
G Npm3 nucleophosmin/nucleoplasmin, 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:244,595,638...244,597,623
Ensembl chr 1:244,595,644...244,597,591
JBrowse link
G Nras NRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Adenocarcinoma of lung ClinVar PMID:1654209 PMID:2278970 PMID:2674680 PMID:3122217 PMID:6587382 More... NCBI chr 2:190,582,885...190,593,509
Ensembl chr 2:190,582,918...190,591,626
JBrowse link
G Nudt21 nudix hydrolase 21 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr19:10,974,800...10,993,841
Ensembl chr19:10,974,241...10,991,682
JBrowse link
G Nuf2 NUF2 component of NDC80 kinetochore complex disease_progression ISO RGD PMID:32226507 RGD:28912743 NCBI chr13:81,693,675...81,722,765
Ensembl chr13:81,693,598...81,722,766
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23951099 NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766
JBrowse link
G Pabpc4 poly(A) binding protein, cytoplasmic 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 5:135,563,142...135,578,985
Ensembl chr 5:135,563,562...135,578,979
JBrowse link
G Pacrg parkin coregulated ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:12719539 NCBI chr 1:49,882,671...50,305,564
Ensembl chr 1:49,882,630...50,305,430
JBrowse link
G Pcbd1 pterin-4 alpha-carbinolamine dehydratase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr20:29,037,545...29,044,322
Ensembl chr20:28,953,864...29,044,292
Ensembl chr20:28,953,864...29,044,292
JBrowse link
G Pign phosphatidylinositol glycan anchor biosynthesis, class N ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr13:21,659,092...21,812,932
Ensembl chr13:21,662,455...21,806,790
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Adenocarcinoma of lung, somatic | ClinVar Annotator: match by term: Lung adenocarcinoma
CTD
ClinVar
PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 More... NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 ISO mRNA:decreased expression:lung RGD PMID:26695082 RGD:13464334 NCBI chr 2:32,878,942...32,963,611
Ensembl chr 2:32,882,032...32,963,631
JBrowse link
G Plcg1 phospholipase C, gamma 1 exacerbates ISO protein:decreased expression:lung (human) RGD PMID:33077911 RGD:151356960 NCBI chr 3:149,385,587...149,416,330
Ensembl chr 3:149,385,587...149,416,330
JBrowse link
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 disease_progression ISO RGD PMID:29072684 RGD:151665822 NCBI chr 8:93,084,548...93,167,255
Ensembl chr 8:93,084,513...93,167,255
JBrowse link
G Polr1d RNA polymerase I and III subunit D ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr12:7,970,592...8,004,157
Ensembl chr12:7,970,595...8,005,624
JBrowse link
G Ppan peter pan homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 8:19,423,908...19,427,941
Ensembl chr 8:19,423,961...19,427,938
JBrowse link
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha ISO ClinVar Annotator: match by term: Adenocarcinoma of lung ClinVar PMID:25741868 PMID:26168268 PMID:26619011 PMID:28492532 NCBI chr 1:60,540,223...60,559,467
Ensembl chr 1:60,540,194...60,560,129
JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974
JBrowse link
G Prame PRAME nuclear receptor transcriptional regulator ISO mRNA:decreased expression:lung (human) RGD PMID:27241212 RGD:11535020 NCBI chr  X:98,567,994...98,574,654
Ensembl chr  X:98,569,415...98,572,096
JBrowse link
G Prdm1 PR/SET domain 1 exacerbates ISO RGD PMID:28378641 RGD:150530469 NCBI chr20:47,959,858...47,981,488
Ensembl chr20:47,959,858...47,981,488
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:12719539 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
JBrowse link
G Psat1 phosphoserine aminotransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:213,196,709...213,218,564
Ensembl chr 1:213,196,709...213,218,682
JBrowse link
G Ptch1 patched 1 ISO RGD PMID:33359005 RGD:150524339 NCBI chr17:1,542,705...1,607,730
Ensembl chr17:1,542,877...1,607,333
JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 ISO ClinVar Annotator: match by term: Adenocarcinoma of lung ClinVar PMID:26619011 PMID:26822237 NCBI chr12:35,365,436...35,424,925
Ensembl chr12:35,383,144...35,424,925
JBrowse link
G Ptpn13 protein tyrosine phosphatase, non-receptor type 13 exacerbates
susceptibility
ISO mRNA,protein:decreased expression:lung
DNA:missense mutations:cds:p.I1522M, p.Y2081D (human)
RGD PMID:22245727 PMID:33536603 PMID:19672627 RGD:152176663, RGD:152975626, RGD:152176665 NCBI chr14:6,108,202...6,282,619
Ensembl chr14:6,108,211...6,282,563
JBrowse link
G Ptprb protein tyrosine phosphatase, receptor type, B disease_progression ISO mRNA:altered expression:lung (human)
mRNA:decreased expression:lung (human)
RGD PMID:29254206 PMID:7981622 RGD:151665107, RGD:151665112 NCBI chr 7:51,953,375...52,034,751
Ensembl chr 7:51,930,015...52,034,748
JBrowse link
G Ptprj protein tyrosine phosphatase, receptor type, J susceptibility ISO DNA:missense mutations:cds:p.R326Q, p.Q276P (human) RGD PMID:19672627 RGD:152176665 NCBI chr 3:76,405,917...76,561,842
Ensembl chr 3:76,405,927...76,562,260
JBrowse link
G Rac1 Rac family small GTPase 1 exacerbates ISO mRNA:increased expression:lung (human) RGD PMID:31779616 RGD:152998910 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase ISO ClinVar Annotator: match by term: Adenocarcinoma of lung ClinVar PMID:1760348 PMID:8601312 PMID:10064593 PMID:12077328 PMID:17603482 More... NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
JBrowse link
G Rangrf RAN guanine nucleotide release factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr10:53,677,467...53,678,880
Ensembl chr10:53,677,467...53,678,840
JBrowse link
G Rarb retinoic acid receptor, beta ISO DNA:hypomethylation:lung RGD PMID:26695082 RGD:13464334 NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288
JBrowse link
G Rasa1 RAS p21 protein activator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr 2:15,857,704...15,940,757
Ensembl chr 2:15,857,980...15,940,854
JBrowse link
G Rbm10 RNA binding motif protein 10 ISO mRNA, protein:decreased expression:lung
DNA:missense mutations, protein-truncating variants: :multiple
RGD PMID:29085465 PMID:22980975 PMID:30955253 RGD:151356983, RGD:11097386, RGD:151356984 NCBI chr  X:1,540,399...1,572,571
Ensembl chr  X:1,540,398...1,572,575
JBrowse link
G Rcl1 RNA terminal phosphate cyclase-like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:226,824,524...226,869,046
Ensembl chr 1:226,824,534...226,902,315
JBrowse link
G Rfc4 replication factor C subunit 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr11:77,749,642...77,764,123
Ensembl chr11:77,749,638...77,764,122
JBrowse link
G Rhoa ras homolog family member A ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:26619011 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G Rnaseh2a ribonuclease H2, subunit A ISO CTD Direct Evidence: marker/mechanism CTD PMID:34254728 NCBI chr19:23,186,325...23,196,045
Ensembl chr19:23,186,383...23,196,041
JBrowse link
G Rnf43 ring finger protein 43 severity ISO human cells in a mouse model RGD PMID:31286874 RGD:151361222 NCBI chr10:72,461,508...72,535,977
Ensembl chr10:72,464,348...72,536,977
JBrowse link
G Ros1 ROS proto-oncogene 1 , receptor tyrosine kinase ISO ClinVar Annotator: match by term: Lung adenocarcinoma
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
PMID:22215748 PMID:23724914 NCBI chr20:31,432,636...31,583,998
Ensembl chr20:31,432,637...31,583,865
JBrowse link
G Rpl10a ribosomal protein L10A ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr20:6,388,800...6,391,358
Ensembl chr20:6,385,823...6,391,357
JBrowse link
G Rpl13a ribosomal protein L13A ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:95,609,374...95,612,557
Ensembl chr 1:95,609,370...95,620,463
JBrowse link
G Rpl27a ribosomal protein L27A ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:163,539,732...163,542,771 JBrowse link
G Rpl36a ribosomal protein L36A ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr  X:97,766,179...97,768,892
Ensembl chr  X:97,766,179...97,768,892
JBrowse link
G Rpsa ribosomal protein SA ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 8:119,851,225...119,855,103
Ensembl chr 8:119,851,225...119,855,247
JBrowse link
G Rrm1 ribonucleotide reductase catalytic subunit M1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:156,823,960...156,848,262
Ensembl chr 1:156,823,960...156,848,261
JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773
JBrowse link
G Rrs1 ribosome biogenesis regulator 1 homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 5:9,733,486...9,735,119
Ensembl chr 5:9,733,091...9,735,140
JBrowse link
G Runx1 RUNX family transcription factor 1 ISO RGD PMID:28926105 RGD:126779571 NCBI chr11:31,839,880...32,074,427
Ensembl chr11:31,843,764...32,074,542
JBrowse link
G Satb1 SATB homeobox 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 9:4,677,817...4,773,061
Ensembl chr 9:4,680,920...4,753,251
JBrowse link
G Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N ISO protein:increased expression:cytoplasm RGD PMID:8620411 RGD:5147446 NCBI chr 6:123,323,632...123,331,166
Ensembl chr 6:123,323,629...123,332,433
JBrowse link
G Setd2 SET domain containing 2, histone lysine methyltransferase ameliorates
exacerbates
severity
ISO human cells and genes in mouse model
DNA:mutations:multiple (human)
RGD PMID:33223508 PMID:27687306 PMID:33707235 PMID:28202515 RGD:150429633, RGD:150429649, RGD:150429648, RGD:126848875 NCBI chr 8:110,511,808...110,597,489
Ensembl chr 8:110,511,772...110,597,489
JBrowse link
G Sfn stratifin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 Ensembl chr 5:145,826,201...145,831,314 JBrowse link
G Sftpc surfactant protein C ISO CTD Direct Evidence: marker/mechanism CTD PMID:25851810 NCBI chr15:45,596,565...45,599,615
Ensembl chr15:45,596,574...45,610,777
JBrowse link
G Sfxn1 sideroflexin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr17:10,486,250...10,522,640
Ensembl chr17:10,486,271...10,522,529
JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr10:45,468,698...45,497,820
Ensembl chr10:45,468,700...45,497,820
JBrowse link
G Slc15a2 solute carrier family 15 member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr11:64,014,182...64,043,228
Ensembl chr11:64,014,182...64,043,225
JBrowse link
G Slc19a1 solute carrier family 19 member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr20:11,584,410...11,602,429
Ensembl chr20:11,584,411...11,601,972
JBrowse link
G Slc1a5 solute carrier family 1 member 5 disease_progression ISO RGD PMID:26279756 RGD:151361150 NCBI chr 1:77,456,849...77,470,952
Ensembl chr 1:77,456,694...77,470,952
JBrowse link
G Slc22a18 solute carrier family 22, member 18 disease_progression ISO mRNA:increased expression:lung (human) RGD PMID:32726996 RGD:150557423 NCBI chr 1:198,670,626...198,694,977
Ensembl chr 1:198,671,731...198,694,975
JBrowse link
G Slc3a2 solute carrier family 3 member 2 disease_progression ISO RGD PMID:19171406 RGD:151361151 NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931
JBrowse link
G Slc4a4 solute carrier family 4 member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr14:18,841,289...19,293,297
Ensembl chr14:18,845,159...19,272,883
JBrowse link
G Slc4a7 solute carrier family 4 member 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr15:10,585,307...10,664,781
Ensembl chr15:10,588,979...10,664,781
JBrowse link
G Slc7a5 solute carrier family 7 member 5 disease_progression ISO RGD PMID:26279756 PMID:19171406 RGD:151361150, RGD:151361151 NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823
JBrowse link
G Smad4 SMAD family member 4 ISO ClinVar Annotator: match by term: Adenocarcinoma of lung ClinVar PMID:6604412 PMID:8898652 PMID:9214508 PMID:9285566 PMID:9582123 More... NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438
JBrowse link
G Smarcc1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 8:110,111,097...110,214,727
Ensembl chr 8:110,111,122...110,214,720
JBrowse link
G Snord22 small nucleolar RNA, C/D box 22 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr11:9,097,799...9,097,923
Ensembl chr11:9,097,799...9,097,923
JBrowse link
G Snrpb small nuclear ribonucleoprotein polypeptides B and B1 severity ISO mRNA:increased expression:lung (human) RGD PMID:22876301 RGD:10768834 NCBI chr 3:117,369,816...117,379,344
Ensembl chr 3:117,370,100...117,379,339
JBrowse link
G Snrpe small nuclear ribonucleoprotein polypeptide E severity ISO mRNA:increased expression:lung (human) RGD PMID:22876301 RGD:10768834 NCBI chr13:45,050,986...45,057,231
Ensembl chr13:45,050,986...45,057,310
JBrowse link
G Snrpg small nuclear ribonucleoprotein polypeptide G ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 4:118,812,278...118,819,827
Ensembl chr 4:118,812,252...118,819,826
JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 ISO ClinVar Annotator: match by term: Lung adenocarcinoma
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
PMID:26619011 PMID:27158780 NCBI chr 6:14,533,870...14,613,348
Ensembl chr 6:14,533,360...14,611,107
JBrowse link
G Sox2 SRY-box transcription factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25184679 NCBI chr 2:117,536,929...117,539,338
Ensembl chr 2:117,536,929...117,539,338
JBrowse link
G Sox30 SRY-box transcription factor 30 disease_progression ISO RGD PMID:26330328 RGD:11535423 NCBI chr10:30,417,499...30,446,441
Ensembl chr10:30,418,473...30,446,453
JBrowse link
G Sox4 SRY-box transcription factor 4 ISO protein:increased expression:lung RGD PMID:29882245 RGD:153297792 NCBI chr17:35,667,809...35,672,515
Ensembl chr17:35,667,537...35,673,665
JBrowse link
G Spop speckle type BTB/POZ protein ameliorates ISO human gene and cell line in mouse model
mRNA, protein:increased expression:lung (human)
RGD PMID:30607139 PMID:31105033 RGD:153298920, RGD:153298927 NCBI chr10:80,358,121...80,438,983
Ensembl chr10:80,358,124...80,483,955
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase severity ISO RGD PMID:12826049 RGD:150521546 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Srm spermidine synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 5:159,025,919...159,029,076
Ensembl chr 5:159,025,873...159,029,405
JBrowse link
G Srr serine racemase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr10:59,769,563...59,786,688
Ensembl chr10:59,769,571...59,787,011
JBrowse link
G Srsf1 serine and arginine rich splicing factor 1 severity ISO RGD PMID:23071587 RGD:150429662 NCBI chr10:72,838,926...72,859,066
Ensembl chr10:72,839,274...72,845,336
JBrowse link
G Srsf2 serine and arginine rich splicing factor 2 severity ISO RGD PMID:23071587 RGD:150429662 NCBI chr10:102,052,158...102,055,365
Ensembl chr10:102,052,314...102,055,338
JBrowse link
G Stk11 serine/threonine kinase 11 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma
CTD
ClinVar
PMID:10408777 PMID:12865922 PMID:15863673 PMID:16287113 PMID:16582077 More... NCBI chr 7:9,574,553...9,591,315
Ensembl chr 7:9,575,269...9,591,315
JBrowse link
G Stk39 serine threonine kinase 39 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 3:52,913,583...53,179,060
Ensembl chr 3:52,913,585...53,179,060
JBrowse link
G Strbp spermatid perinuclear RNA binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 3:21,328,310...21,467,753
Ensembl chr 3:21,337,855...21,414,949
JBrowse link
G Suclg2 succinate-CoA ligase GDP-forming subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 4:128,067,031...128,337,146
Ensembl chr 4:128,067,033...128,337,170
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 ISO DNA:SNP:exon:p.R213H, 638G>A (human) RGD PMID:14688021 RGD:1581441 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562
JBrowse link
G Tert telomerase reverse transcriptase susceptibility ISO DNA:SNP: :rs2736098(human)
DNA:SNP::rs33963617(human)
DNA:SNP:: rs2736100(human)
DNA:SNPs:: rs2853669,rs2736108(human)
RGD PMID:23738012 PMID:31935503 PMID:24761905 PMID:19955392 PMID:23908149 RGD:150530485, RGD:150530635, RGD:150530628, RGD:150530502, RGD:150530498 NCBI chr 1:29,637,213...29,659,509
Ensembl chr 1:29,637,506...29,659,561
JBrowse link
G Tf transferrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511
JBrowse link
G Timm10 translocase of inner mitochondrial membrane 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 3:69,908,397...69,911,943
Ensembl chr 3:69,908,456...69,911,940
JBrowse link
G Timm8a1 translocase of inner mitochondrial membrane 8A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr  X:97,717,932...97,721,918
Ensembl chr  X:97,717,920...97,721,960
JBrowse link
G Tk1 thymidine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr10:103,034,755...103,046,125
Ensembl chr10:103,031,521...103,046,920
JBrowse link
G Tnfsf10 TNF superfamily member 10 ISO CTD Direct Evidence: therapeutic CTD PMID:24345465 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link
G Tomm40 translocase of outer mitochondrial membrane 40 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:79,358,781...79,370,976
Ensembl chr 1:79,358,786...79,370,915
JBrowse link
G Top2a DNA topoisomerase II alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr10:83,946,186...83,975,694
Ensembl chr10:83,945,735...83,976,874
JBrowse link
G Tp53 tumor protein p53 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Adenocarcinoma of lung, somatic | ClinVar Annotator: match by term: Lung adenocarcinoma
CTD
ClinVar
PMID:1349175 PMID:1359493 PMID:1565143 PMID:1565144 PMID:1569604 More... NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tp63 tumor protein p63 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24880342 NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398
JBrowse link
G Tpi1 triosephosphate isomerase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541
JBrowse link
G Traf4 Tnf receptor associated factor 4 ISO mRNA:increased expression:lung (human) RGD PMID:29254206 RGD:151665107 NCBI chr10:63,054,169...63,060,284
Ensembl chr10:63,054,181...63,060,284
JBrowse link
G Ttf1 transcription termination factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25851810 NCBI chr 3:12,384,626...12,409,257
Ensembl chr 3:12,384,655...12,409,257
JBrowse link
G Ttr transthyretin ISO mRNA,protein:increased expression:lung (human) RGD PMID:26943652 RGD:151665207 NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008
JBrowse link
G Tyms thymidylate synthetase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536
JBrowse link
G U2af1 U2 small nuclear RNA auxiliary factor 1 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:22158538 PMID:23029227 PMID:23861105 PMID:24498085 PMID:26619011 NCBI chr20:9,742,904...9,753,840
Ensembl chr20:9,742,905...9,753,832
JBrowse link
G Ubr5 ubiquitin protein ligase E3 component n-recognin 5 ameliorates ISO human cell line in a mouse model RGD PMID:32867711 RGD:151665200 NCBI chr 7:69,116,758...69,224,490
Ensembl chr 7:69,116,761...69,224,903
JBrowse link
G Uck2 uridine-cytidine kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr13:79,380,807...79,438,352
Ensembl chr13:79,383,846...79,438,352
JBrowse link
G Vav1 vav guanine nucleotide exchange factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr 9:2,161,985...2,209,951
Ensembl chr 9:2,157,900...2,208,937
JBrowse link
G Wrap53 WD repeat containing, antisense to TP53 severity ISO RGD PMID:28347242 RGD:21081522 NCBI chr10:54,282,092...54,299,908
Ensembl chr10:54,282,105...54,298,929
JBrowse link
G Xpc XPC complex subunit, DNA damage recognition and repair factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:21327329 PMID:27777383 NCBI chr 4:123,993,670...124,020,922
Ensembl chr 4:123,993,666...124,021,010
JBrowse link
G Xpo1 exportin 1 exacerbates ISO circRNA:increased expression:lung (human) RGD PMID:33268793 RGD:151665799 NCBI chr14:97,233,263...97,275,536
Ensembl chr14:97,233,270...97,275,498
JBrowse link
G Xrcc1 X-ray repair cross complementing 1 susceptibility
severity
ISO DNA:missense mutation:cds: p.R399Q (human)
DNA:missense mutation:exon 10: p.R399Q (rs25487) (human)
RGD PMID:11104903 PMID:20003463 RGD:151347406, RGD:151347422 NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701
JBrowse link
G Xrcc5 X-ray repair cross complementing 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 9:73,955,220...74,044,020
Ensembl chr 9:73,955,216...74,044,018
JBrowse link
G Xrcc6 X-ray repair cross complementing 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 7:113,542,992...113,563,762
Ensembl chr 7:113,543,057...113,563,762
JBrowse link
G Zfhx3 zinc finger homeobox 3 ameliorates ISO DNA:mutations:multiple (human) RGD PMID:32653938 RGD:151361163 NCBI chr19:36,257,196...36,886,104
Ensembl chr19:36,630,254...36,881,771
JBrowse link
lung large cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrna5 cholinergic receptor nicotinic alpha 5 subunit ISO mRNA:increased expression:lung RGD PMID:20124469 RGD:150527851 NCBI chr 8:55,369,794...55,398,526
Ensembl chr 8:55,369,794...55,398,146
JBrowse link
G Ptpn13 protein tyrosine phosphatase, non-receptor type 13 ISO mRNA,protein:decreased expression:lung RGD PMID:22245727 RGD:152176663 NCBI chr14:6,108,202...6,282,619
Ensembl chr14:6,108,211...6,282,563
JBrowse link
G Ttr transthyretin ISO protein:increased expression:lung (human) RGD PMID:26943652 RGD:151665207 NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008
JBrowse link
lung non-small cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A treatment ISO DNA:SNPs: :2677G>T, 3435C>T(human)
ClinVar Annotator: match by term: Non-small cell lung cancer
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
RGD
PMID:10716719 PMID:11502320 PMID:12686700 PMID:15452305 PMID:15452306 More... RGD:11080964 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 treatment ISO DNA:SNPs: :-24C>T, 3972C>T(human) RGD PMID:17534875 RGD:11080964 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase treatment ISO human cells in mouse model RGD PMID:26758680 RGD:126925226 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065
JBrowse link
G Acvr1b activin A receptor type 1B susceptibility ISO DNA:SNP:intron:rs12809597(human) RGD PMID:22586632 RGD:151665491 NCBI chr 7:132,286,266...132,329,679
Ensembl chr 7:132,286,275...132,329,673
JBrowse link
G Ada adenosine deaminase ISO protein:decreased expression:lymphocyte,erythrocyte: RGD PMID:31375946 RGD:152995295 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088
JBrowse link
G Adam28 ADAM metallopeptidase domain 28 treatment ISO DNA:hypermethylation:promoter RGD PMID:22354764 PMID:21429053 RGD:153297789, RGD:153298914 NCBI chr15:43,774,463...43,840,726
Ensembl chr15:42,944,467...43,840,672
JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19027488 NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103
JBrowse link
G Ager advanced glycosylation end product-specific receptor ISO mRNA, protein:decreased expression:lung (human) RGD PMID:15539404 RGD:7245515 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17094902 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326
JBrowse link
G Akt1 AKT serine/threonine kinase 1 ameliorates
treatment
ISO human cells in mouse model
ClinVar Annotator: match by term: Non-small cell lung cancer
ClinVar
RGD
PMID:17611497 PMID:18256540 PMID:18392055 PMID:18504432 PMID:18611285 More... RGD:5133243, RGD:151357000, RGD:150404268 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Akt2 AKT serine/threonine kinase 2 ISO ClinVar Annotator: match by term: Non-small cell lung carcinoma ClinVar PMID:21479466 PMID:25157968 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817
JBrowse link
G Akt3 AKT serine/threonine kinase 3 disease_progression ISO RGD PMID:19846969 RGD:13432583 NCBI chr13:88,943,708...89,225,831
Ensembl chr13:88,946,091...89,225,708
JBrowse link
G Alb albumin disease_progression ISO RGD PMID:23778417 RGD:11036091 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Alk ALK receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Non-small cell lung carcinoma
CTD
ClinVar
PMID:17625570 PMID:18923525 PMID:20979469 PMID:20979473 PMID:21030459 More... NCBI chr 6:22,879,653...23,599,636
Ensembl chr 6:22,880,625...23,598,034
JBrowse link
G Amd1 adenosylmethionine decarboxylase 1 disease_progression ISO DNA:SNP: :rs1279590(human) RGD PMID:30650190 RGD:14390072 NCBI chr20:43,695,783...43,711,476
Ensembl chr20:43,697,237...43,711,476
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 ISO mRNA:decreased expression:lung RGD PMID:28982084 RGD:13703106 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
JBrowse link
G Apc APC regulator of WNT signaling pathway ISO CTD Direct Evidence: marker/mechanism CTD PMID:18337602 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696
JBrowse link
G Araf A-Raf proto-oncogene, serine/threonine kinase ISO ClinVar Annotator: match by term: Non-small cell lung carcinoma ClinVar PMID:24569458 PMID:26619011 NCBI chr  X:1,227,392...1,292,356
Ensembl chr  X:1,227,392...1,239,073
JBrowse link
G Areg amphiregulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:15496427 PMID:16230376 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
JBrowse link
G Arid1a AT-rich interaction domain 1A disease_progression
treatment
ISO protein:decreased expression:lung (human)
DNA:mutations
RGD PMID:24566899 PMID:32791957 RGD:126848781, RGD:126848874 NCBI chr 5:145,908,181...145,981,609
Ensembl chr 5:145,908,181...145,985,564
JBrowse link
G Arid1b AT-rich interaction domain 1B treatment ISO DNA:mutations RGD PMID:32791957 RGD:126848874 NCBI chr 1:45,567,991...45,923,644
Ensembl chr 1:45,563,623...45,923,493
JBrowse link
G Arpc5 actin related protein 2/3 complex, subunit 5 ISO mRNA:increased expression:lung (human) RGD PMID:22089643 RGD:11049488 NCBI chr13:64,904,504...64,913,413
Ensembl chr13:64,887,136...64,913,410
JBrowse link
G Atf3 activating transcription factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17043644 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Atm ATM serine/threonine kinase susceptibility
treatment
ISO DNA:SNPs,haplotypes:intron: (rs227060, rs170548) (human)
human cells in mouse model
RGD PMID:17582598 PMID:23632475 RGD:150383340, RGD:150404268 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Aven apoptosis and caspase activation inhibitor ISO CTD Direct Evidence: marker/mechanism CTD PMID:15496427 NCBI chr 3:99,299,009...99,431,635
Ensembl chr 3:99,298,930...99,431,634
JBrowse link
G Axin1 axin 1 disease_progression ISO protein:decreased expression:lung (human) RGD PMID:19735876 RGD:150530290 NCBI chr10:15,163,684...15,215,615
Ensembl chr10:15,163,684...15,215,615
JBrowse link
G Axl Axl receptor tyrosine kinase ISO CTD Direct Evidence: therapeutic CTD PMID:22751098 NCBI chr 1:81,265,656...81,296,278
Ensembl chr 1:81,265,088...81,296,265
JBrowse link
G Bad BCL2-associated agonist of cell death disease_progression ISO protein:decreased expression:lung RGD PMID:21918885 PMID:24092988 RGD:13432584, RGD:13434906 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bag6 BAG cochaperone 6 susceptibility ISO DNA:SNP: :rs3117582(human) RGD PMID:25884493 RGD:14390136 NCBI chr20:3,675,938...3,690,414
Ensembl chr20:3,675,938...3,688,657
JBrowse link
G Bambi BMP and activin membrane-bound inhibitor ISO mRNA,protein:increased expression:lung: RGD PMID:20716422 RGD:14390157 NCBI chr17:54,121,251...54,125,816
Ensembl chr17:54,121,255...54,126,060
JBrowse link
G Bard1 BRCA1 associated RING domain 1 disease_progression ISO RGD PMID:21815143 RGD:127229947 NCBI chr 9:72,616,070...72,694,553
Ensembl chr 9:72,623,155...72,694,265
JBrowse link
G Bax BCL2 associated X, apoptosis regulator treatment ISO human cells in mouse model RGD PMID:23632475 RGD:150404268 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bbc3 Bcl-2 binding component 3 treatment ISO human cells in mouse model RGD PMID:23632475 RGD:150404268 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
JBrowse link
G Bcl11a BAF chromatin remodeling complex subunit BCL11A severity ISO mRNA, protein:increased expression:lung (human) RGD PMID:23758992 RGD:11099968 NCBI chr14:98,029,018...98,124,181
Ensembl chr14:98,030,461...98,124,180
JBrowse link
G Bcorl1 BCL6 co-repressor-like 1 severity ISO RGD PMID:26648304 RGD:11342082 NCBI chr  X:127,516,504...127,584,529
Ensembl chr  X:127,537,538...127,584,087
JBrowse link
G Bend4 BEN domain containing 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28722770 NCBI chr14:40,753,048...40,788,686
Ensembl chr14:40,753,077...40,783,504
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 exacerbates ISO protein:increased expression:lung (human) RGD PMID:27737687 RGD:152998985 NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 exacerbates
ameliorates
ISO protein:increased expression:lung (human)
DNA:SNP:intron: (rs11225211) (human)
RGD PMID:27737687 PMID:32905523 PMID:20959404 RGD:152998985, RGD:153297804, RGD:152999005 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16382892 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase ISO ClinVar Annotator: match by term: Non-small cell lung cancer | ClinVar Annotator: match by term: Non-small cell lung carcinoma ClinVar
RGD
PMID:2102266 PMID:12068308 PMID:12198537 PMID:12447372 PMID:12460918 More... RGD:5133243, RGD:5133242 NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463
JBrowse link
G Brca1 BRCA1, DNA repair associated disease_progression
treatment
ISO DNA:hypermethylation:promoter RGD PMID:23128816 PMID:23335114 PMID:24443257 PMID:21575522 RGD:126925968, RGD:127229949, RGD:127229948, RGD:127229935 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
JBrowse link
G Brd7 bromodomain containing 7 disease_progression ISO protein:increased expression:lung: RGD PMID:22008115 RGD:9586442 NCBI chr19:18,708,792...18,737,500
Ensembl chr19:18,709,022...18,737,494
JBrowse link
G Btk Bruton tyrosine kinase ameliorates ISO mRNA:increased expression:lung (human) RGD PMID:32623229 RGD:151347854 NCBI chr  X:97,722,796...97,762,315
Ensembl chr  X:97,722,802...97,761,853
JBrowse link
G Calr calreticulin ameliorates ISO protein:increased expression:lung (human)
mRNA, protein:increased expression:lung (human)
RGD PMID:26842877 PMID:29228584 RGD:150521685, RGD:150521696 NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414
JBrowse link
G Car9 carbonic anhydrase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30381462 NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838
JBrowse link
G Casp3 caspase 3 ISO DNA:SNP: :77G>A (human)
mRNA:increased expression:lung
RGD PMID:20661084 PMID:16231180 RGD:13434908, RGD:13434909 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp6 caspase 6 ISO mRNA:increased expression:lung RGD PMID:16231180 RGD:13434909 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502
JBrowse link
G Casp7 caspase 7 ISO DNA:SNP: :rs2227310 (human) RGD PMID:20661084 RGD:13434908 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp8 caspase 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20471133 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 no_association ISO DNA, mRNA:SNP, decreased expression:exon, lung:rs1052576 (human)
mRNA:increased expression:lung
mRNA:splice variant:lung
DNA:SNP: :rs4645981 (human)
DNA:SNP:exon:rs1052571 (human)
RGD PMID:17285546 PMID:16231180 PMID:20972334 PMID:20661084 PMID:17285546 RGD:13434907, RGD:13434909, RGD:9999427, RGD:13434908, RGD:13434907 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase ISO CTD Direct Evidence: marker/mechanism CTD PMID:11731445 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cbl Cbl proto-oncogene ISO DNA:missense mutations, loss of heterozygosity:multiple (human) RGD PMID:20126411 RGD:11576301 NCBI chr 8:44,487,824...44,571,620
Ensembl chr 8:44,489,410...44,571,176
JBrowse link
G Cblb Cbl proto-oncogene B disease_progression
treatment
no_association
ISO DNA:SNPs: :rs2305035, rs9657904 (human)
DNA:SNP,haplotype: :rs2305035(human)
DNA:SNPs: :rs3772534 (human)
RGD PMID:29707316 PMID:26732495 PMID:29707316 RGD:126925239, RGD:150540334, RGD:126925239 NCBI chr11:48,589,878...48,756,940
Ensembl chr11:48,592,703...48,756,839
JBrowse link
G Ccnd1 cyclin D1 disease_progression
treatment
ISO DNA:amplification
mRNA:splice variant
DNA:SNP: :870A>G (human)
RGD PMID:26055143 PMID:9462706 PMID:18715616 PMID:16406195 RGD:11052612, RGD:13434928, RGD:13434926, RGD:13434924 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccnd2 cyclin D2 ISO mRNA:increased expression:lung
protein:increased expression:lung
RGD PMID:31253987 PMID:30227870 RGD:151665100, RGD:151665108 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
JBrowse link
G Ccne1 cyclin E1 disease_progression ISO RGD PMID:11212263 RGD:13673913 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Ccnh cyclin H ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr 2:15,834,833...15,855,643
Ensembl chr 2:15,834,833...15,855,819
JBrowse link
G Cd74 CD74 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:22919003 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003
JBrowse link
G Cd9 CD9 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:17043644 NCBI chr 4:158,256,328...158,289,136
Ensembl chr 4:158,256,328...158,289,222
JBrowse link
G Cda cytidine deaminase ISO DNA:snp:cds:p.K27Q (human) RGD PMID:18347182 RGD:2316365 NCBI chr 5:150,556,615...150,583,231
Ensembl chr 5:150,556,615...150,583,231
JBrowse link
G Cdh13 cadherin 13 ISO DNA:hypermethylation:promoter
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:18337602 PMID:11389090 RGD:2293545 NCBI chr19:46,349,562...47,387,462
Ensembl chr19:46,349,430...47,387,459
JBrowse link
G Cdk4 cyclin-dependent kinase 4 disease_progression
treatment
ISO RGD PMID:24959380 PMID:24496383 RGD:13464275, RGD:13464276 NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Cdk6 cyclin-dependent kinase 6 treatment ISO RGD PMID:27874949 PMID:23591808 RGD:13464321, RGD:13464324 NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A treatment ISO human cells in mouse model RGD PMID:23632475 RGD:150404268 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B disease_progression ISO RGD PMID:9500468 RGD:13673920 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:18337602 PMID:19375815 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B disease_progression ISO DNA:hypermethylation:promoter RGD PMID:11445839 RGD:13673922 NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050
JBrowse link
G Cenpa centromere protein A severity ISO mRNA:increased expression:lung (human) RGD PMID:30008938 RGD:36947379 NCBI chr 6:25,700,142...25,711,767
Ensembl chr 6:25,700,142...25,711,675
JBrowse link
G Cert1 ceramide transporter 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15496427 NCBI chr 2:27,882,546...27,987,090
Ensembl chr 2:27,882,555...27,987,074
JBrowse link
G Chfr checkpoint with forkhead and ring finger domains ISO CTD Direct Evidence: marker/mechanism CTD PMID:20705357 NCBI chr12:46,504,497...46,538,104
Ensembl chr12:46,504,497...46,538,014
JBrowse link
G Chga chromogranin A ISO CTD Direct Evidence: marker/mechanism CTD PMID:21595568 NCBI chr 6:121,696,051...121,707,399
Ensembl chr 6:121,696,051...121,707,398
JBrowse link
G Chi3l1 chitinase 3 like 1 severity ISO protein:increased secretion:serum (human) RGD PMID:20564116 RGD:4892660 NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787
JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit disease_progression
susceptibility
ISO DNA:SNP: :rs6495309(human)
DNA:SNP:exon: (rs1051730) (human)
RGD PMID:22722785 PMID:21747048 RGD:151347532, RGD:151660346 NCBI chr 8:55,401,981...55,415,012
Ensembl chr 8:55,401,702...55,415,165
JBrowse link
G Chrna5 cholinergic receptor nicotinic alpha 5 subunit disease_progression ISO DNA:SNP: :rs667282(human) RGD PMID:27050379 RGD:150527847 NCBI chr 8:55,369,794...55,398,526
Ensembl chr 8:55,369,794...55,398,146
JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit ameliorates ISO RGD PMID:19151195 PMID:19326440 RGD:151667906, RGD:151667908 NCBI chr 1:116,715,286...116,837,223
Ensembl chr 1:116,714,711...116,837,240
JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit severity ISO RGD PMID:25172267 RGD:151361147 NCBI chr 8:55,418,379...55,436,967
Ensembl chr 8:55,418,313...55,437,027
JBrowse link
G Clptm1l CLPTM1-like disease_progression
no_association
ISO CTD Direct Evidence: marker/mechanism
DNA:SNPs: :rs4975616,rs401681(human)
DNA:SNP: :rs31490(human)
DNA:SNPs:: rs401681,rs4975616(human)
CTD
RGD
PMID:22675468 PMID:24679952 PMID:27982019 PMID:24175795 RGD:150530644, RGD:150530632, RGD:150530500 NCBI chr 1:29,667,545...29,683,530
Ensembl chr 1:29,667,545...29,683,530
JBrowse link
G Cmpk1 cytidine/uridine monophosphate kinase 1 severity ISO DNA:snps:intron:IVS1+1057C>A rs4492666, IVS1-928C>A rs11211524 (human) RGD PMID:21642870 RGD:5133252 NCBI chr 5:128,480,301...128,507,830
Ensembl chr 5:128,480,301...128,507,830
JBrowse link
G Col7a1 collagen type VII alpha 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:30381462 NCBI chr 8:109,604,877...109,637,252
Ensembl chr 8:109,604,861...109,637,252
JBrowse link
G Coro1c coronin 1C ISO CTD Direct Evidence: marker/mechanism CTD PMID:15496427 NCBI chr12:42,712,960...42,785,179
Ensembl chr12:42,712,991...42,785,179
JBrowse link
G Csf1r colony stimulating factor 1 receptor ameliorates
severity
ISO human cells in a mouse model
mRNA,protein:increased expression:lung (human)
mRNA:decreased expression:lung (human)
DNA:missense mutation:CDS:p.H362R (rs10079250) (human)
RGD PMID:27486763 PMID:33428598 PMID:24451080 PMID:28449811 RGD:150524288, RGD:150524295, RGD:150524294, RGD:150524292 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
JBrowse link
G Csf3 colony stimulating factor 3 ISO CTD Direct Evidence: therapeutic CTD PMID:7692001 NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
JBrowse link
G Cst6 cystatin E/M ISO CTD Direct Evidence: marker/mechanism CTD PMID:17043644 NCBI chr 1:202,655,322...202,657,030
Ensembl chr 1:202,655,322...202,657,030
JBrowse link
G Cux1 cut-like homeobox 1 exacerbates ISO mRNA:increased expression:lung (human) RGD PMID:28405678 RGD:152985544 NCBI chr12:20,107,062...20,425,868
Ensembl chr12:20,107,311...20,425,866
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 disease_progression ISO protein:increased expression:lung (human) RGD PMID:22977534 RGD:152023747 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
JBrowse link
G Cycs cytochrome c, somatic severity
treatment
ISO protein:decreased expression:serum RGD PMID:25578497 PMID:25578497 RGD:13792769, RGD:13792769 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
JBrowse link
G Cyld CYLD lysine 63 deubiquitinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:17043644 NCBI chr19:18,310,632...18,373,696
Ensembl chr19:18,314,019...18,373,658
JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 exacerbates
susceptibility
disease_progression
ISO mRNA:increased expression:lung (human)
DNA:SNPs:multiple (human)
DNA:SNPs:CDS, 3' utr: (rs6068816, rs4809957) (human)
DNA:SNP:exon, intron: (rs6068816, rs2181874) (human)
DNA:SNP:intron 4: (rs3787554) (human)
RGD PMID:29250167 PMID:29726119 PMID:17671213 PMID:25544771 PMID:27669215 More... RGD:151361179, RGD:151708739, RGD:151708738, RGD:151665789, RGD:151665175, RGD:151361185, RGD:151361182 NCBI chr 3:159,275,947...159,290,383
Ensembl chr 3:159,275,947...159,290,383
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16142352 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Dab2ip DAB2 interacting protein disease_progression ISO protein:decreased expression:lung (human) RGD PMID:31849482 RGD:151665206 NCBI chr 3:18,915,290...19,086,282
Ensembl chr 3:18,915,290...19,086,280
JBrowse link
G Dapk1 death associated protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11313923 NCBI chr17:3,930,223...4,090,991
Ensembl chr17:3,930,213...4,090,991
JBrowse link
G Ddr1 discoidin domain receptor tyrosine kinase 1 disease_progression ISO RGD PMID:17299390 RGD:150429714 NCBI chr20:3,042,494...3,064,442
Ensembl chr20:3,044,320...3,064,468
JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 ISO mRNA:decreased expression:lung
ClinVar Annotator: match by term: Non-small cell lung carcinoma
ClinVar
RGD
PMID:18938156 PMID:22328973 PMID:23932362 PMID:28492532 PMID:17299390 RGD:150429714 NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363
JBrowse link
G Deup1 deuterosome assembly protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr 8:12,380,300...12,442,649
Ensembl chr 8:12,380,302...12,442,199
JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein ISO mRNA:increased expression:lung RGD PMID:16231180 RGD:13434909 NCBI chr12:33,055,784...33,070,400
Ensembl chr12:33,055,263...33,070,387
JBrowse link
G Dnai7 dynein axonemal intermediate chain 7 ameliorates ISO RGD PMID:24860162 RGD:152998908 NCBI chr 4:178,143,499...178,179,871
Ensembl chr 4:178,143,500...178,179,980
JBrowse link
G Dnmt1 DNA methyltransferase 1 treatment ISO RGD PMID:32211850 PMID:32211850 RGD:126848780, RGD:126848780 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
JBrowse link
G Dusp3 dual specificity phosphatase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15496427 NCBI chr10:86,920,014...86,933,739
Ensembl chr10:86,920,014...86,933,962
JBrowse link
G E2f1 E2F transcription factor 1 treatment
disease_progression
severity
ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:29754146 PMID:28498400 PMID:12358350 PMID:12237873 PMID:23543735 RGD:13464333, RGD:13464343, RGD:13464342, RGD:9590260 NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361
JBrowse link
G E2f2 E2F transcription factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29754146 NCBI chr 5:148,399,193...148,422,595
Ensembl chr 5:148,399,642...148,421,217
JBrowse link
G E2f3 E2F transcription factor 3 disease_progression ISO DNA:SNP: :rs3806116 (human)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:29754146 PMID:27557513 RGD:13464345 NCBI chr17:34,601,756...34,679,139
Ensembl chr17:34,601,830...34,676,253
JBrowse link
G E2f5 E2F transcription factor 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29754146 NCBI chr 2:86,997,331...87,012,901
Ensembl chr 2:86,997,332...87,012,990
JBrowse link
G E2f6 E2F transcription factor 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29754146 NCBI chr 6:39,592,224...39,608,685
Ensembl chr 6:39,592,228...39,608,683
JBrowse link
G E2f7 E2F transcription factor 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29754146 NCBI chr 7:46,150,533...46,192,739
Ensembl chr 7:46,151,293...46,192,734
JBrowse link
G E2f8 E2F transcription factor 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29754146 NCBI chr 1:98,565,717...98,584,265
Ensembl chr 1:98,565,717...98,584,098
JBrowse link
G Eef2 eukaryotic translation elongation factor 2 disease_progression ISO protein:increased expression:blood serum (human) RGD PMID:24377563 RGD:153298905 NCBI chr 7:8,533,248...8,538,518
Ensembl chr 7:8,533,116...8,559,183
JBrowse link
G Egf epidermal growth factor treatment ISO RGD PMID:26927662 PMID:25992884 RGD:13464348, RGD:13464350 NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Egfr epidermal growth factor receptor ameliorates
severity
treatment
susceptibility
ISO ClinVar Annotator: match by term: Non-small cell lung cancer | ClinVar Annotator: match by term: Non-small cell lung carcinoma | ClinVar Annotator: match by term: Nonsmall cell lung cancer, response to tyrosine kinase inhibitor in, somatic
human cells in mouse model
CTD Direct Evidence: marker/mechanism
protein:decreased expression:tumor (human)
DNA:deletion:cds:2240del18 (human)
ClinVar
CTD
RGD
PMID:2302402 PMID:11423618 PMID:15118073 PMID:15118125 PMID:15272417 More... RGD:5133242, RGD:151357000, RGD:126790479, RGD:13464349, RGD:5131629, RGD:5131640, RGD:1601010, RGD:5133241 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Egr1 early growth response 1 resistance ISO mRNA:increased expression:tumor (human) RGD PMID:15774784 RGD:5131925 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 treatment ISO human cells in mouse model RGD PMID:23632475 RGD:150404268 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
JBrowse link
G Eml4 EMAP like 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17625570 PMID:21757253 PMID:21767331 PMID:22568572 PMID:22617245 More... NCBI chr 6:11,219,545...11,334,824
Ensembl chr 6:11,219,566...11,334,879
JBrowse link
G Eno1 enolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17094902 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
JBrowse link
G Eno2 enolase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21595568 NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980
JBrowse link
G Epas1 endothelial PAS domain protein 1 treatment ISO RGD PMID:21812995 RGD:10395382 NCBI chr 6:7,790,236...7,871,246
Ensembl chr 6:7,790,647...7,871,228
JBrowse link
G Ephx1 epoxide hydrolase 1 disease_progression ISO RGD PMID:17273734 RGD:4889124 NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 ISO ClinVar Annotator: match by term: Non-small cell lung carcinoma ClinVar
RGD
PMID:15457249 PMID:15753357 PMID:16638863 PMID:16863509 PMID:18334834 More... RGD:5133243 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 treatment
disease_progression
ISO RGD PMID:20364069 PMID:11789762 RGD:126790478, RGD:126790479 NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525
JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit disease_progression
treatment
severity
ISO CTD Direct Evidence: marker/mechanism
DNA:silent mutation:cds:p.N118N (human)
protein:decreased expression:lung (human)
CTD
RGD
PMID:21553054 PMID:23912706 PMID:23549037 PMID:24443257 PMID:15140544 More... RGD:127229950, RGD:127229948, RGD:13207428, RGD:13207308 NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963
JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit disease_progression ISO DNA:polymorphism:cds:p.K751Q(human)
ClinVar Annotator: match by term: Non-small cell lung carcinoma
ClinVar
RGD
PMID:19434073 PMID:19470925 PMID:24033266 PMID:24728327 PMID:25741868 More... RGD:12880391 NCBI chr 1:79,033,342...79,047,102
Ensembl chr 1:79,033,326...79,047,102
JBrowse link
G Ercc3 ERCC excision repair 3, TFIIH core complex helicase subunit treatment ISO DNA:snp:intron:c.2064+741T>C (rs3738948) (human) RGD PMID:25069034 RGD:11098167 NCBI chr18:23,883,613...23,914,326
Ensembl chr18:23,883,580...23,914,329
JBrowse link
G Ercc5 ERCC excision repair 5, endonuclease treatment ISO RGD PMID:24782167 RGD:151347410 NCBI chr 9:46,309,477...46,354,478
Ensembl chr 9:46,309,389...46,354,472
JBrowse link
G Ergic3 ERGIC and golgi 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27588471 NCBI chr 3:144,525,059...144,534,813
Ensembl chr 3:144,525,092...144,534,813
JBrowse link
G Esr1 estrogen receptor 1 ISO DNA:hypermethylation: :lung RGD PMID:19506903 RGD:4892255 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit disease_progression ISO RGD PMID:21539681 PMID:23300840 RGD:126781700, RGD:126781715 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362
JBrowse link
G Fap fibroblast activation protein, alpha disease_progression ISO RGD PMID:29415055 RGD:152600902 NCBI chr 3:47,138,823...47,207,671
Ensembl chr 3:47,138,813...47,225,545
JBrowse link
G Faslg Fas ligand ISO CTD Direct Evidence: marker/mechanism CTD PMID:21807637 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fat1 FAT atypical cadherin 1 treatment ISO CTD Direct Evidence: therapeutic CTD
RGD
PMID:34390292 PMID:31085721 RGD:151347689 NCBI chr16:47,177,253...47,296,261
Ensembl chr16:47,177,248...47,296,107
JBrowse link
G Fbxo11 F-box protein 11 treatment ISO RGD PMID:31778188 RGD:152025265 NCBI chr 6:6,486,761...6,562,664
Ensembl chr 6:6,486,015...6,562,662
JBrowse link
G Fgf9 fibroblast growth factor 9 severity ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:lung (human)
CTD
RGD
PMID:19358281 PMID:24239165 PMID:31884893 RGD:152177524, RGD:152177912 NCBI chr15:32,208,993...32,254,952
Ensembl chr15:32,210,074...32,253,309
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 disease_progression ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:22286583 PMID:27794399 PMID:23806793 RGD:25330355 NCBI chr16:66,492,445...66,546,731
Ensembl chr16:66,494,042...66,547,350
JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 disease_progression
severity
ISO mRNA, protein:increased expression:lung (human)
DNA:SNP:exon 9: p.G3888R (rs351855) (human)
RGD PMID:26045670 PMID:23524567 RGD:150429970, RGD:150429982 NCBI chr17:9,461,541...9,476,268
Ensembl chr17:9,461,547...9,476,242
JBrowse link
G Fh fumarate hydratase severity ISO DNA:SNP: (rs1414493) (human) RGD PMID:25576295 RGD:150340558 NCBI chr13:87,524,331...87,550,215
Ensembl chr13:87,524,337...87,550,266
JBrowse link
G Fhit fragile histidine triad diadenosine triphosphatase disease_progression ISO CTD Direct Evidence: marker/mechanism
DNA:loss of heterozygosity:intron:
CTD
RGD
PMID:11788890 PMID:9635574 PMID:9850082 RGD:13792815, RGD:13792770 NCBI chr15:13,935,029...15,442,620
Ensembl chr15:13,934,995...15,442,340
JBrowse link
G Foxa1 forkhead box A1 disease_progression ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:lung
CTD
RGD
PMID:32717239 PMID:26658322 PMID:26909612 RGD:11554787, RGD:151665747 NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188
JBrowse link
G Foxa2 forkhead box A2 ISO mRNA:decreased expression:lung RGD PMID:26658322 RGD:11554787 NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326
JBrowse link
G Foxl2 forkhead box L2 ISO DNA:hypermethylation: (human) RGD PMID:23599765 RGD:13503323 NCBI chr 8:99,512,971...99,514,500
Ensembl chr 8:99,513,303...99,514,427
JBrowse link
G Foxm1 forkhead box M1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18345025 PMID:19672312 NCBI chr 4:161,639,561...161,652,012
Ensembl chr 4:161,638,816...161,650,684
JBrowse link
G Foxo3 forkhead box O3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19380174 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
JBrowse link
G Frzb frizzled-related protein ISO DNA:hypermethylation:exon 1 RGD PMID:27623992 RGD:32716395 NCBI chr 3:65,332,274...65,365,208
Ensembl chr 3:65,332,277...65,365,208
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:15496427 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gipr gastric inhibitory polypeptide receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:17094902 NCBI chr 1:78,804,287...78,814,462
Ensembl chr 1:78,805,593...78,814,462
JBrowse link
G Gnaq G protein subunit alpha q disease_progression ISO RGD PMID:24518087 RGD:126781753 NCBI chr 1:213,425,631...213,671,947
Ensembl chr 1:213,424,465...213,667,672
JBrowse link
G Gpr135 G protein-coupled receptor 135 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28722770 NCBI chr 6:90,627,533...90,636,311
Ensembl chr 6:90,629,178...90,630,551
JBrowse link
G Gpx1 glutathione peroxidase 1 treatment
onset
ISO DNA:SNP: (human)
mRNA:increased expression:leukocyte (human)
RGD PMID:19347979 PMID:33474835 RGD:152998881, RGD:152998904 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Grik2 glutamate ionotropic receptor kainate type subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr20:52,135,325...52,833,061
Ensembl chr20:52,133,851...52,838,375
JBrowse link
G Gstm2 glutathione S-transferase mu 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19900515 NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961
JBrowse link
G Gstp1 glutathione S-transferase pi 1 susceptibility ISO DNA:SNP: :p.A114V (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphism:exon:p.I105V (human)
CTD
RGD
PMID:17094902 PMID:18258609 PMID:19174490 RGD:4140950, RGD:4140944 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G H19 H19 imprinted maternally expressed transcript disease_progression ISO mRNA:increased expression:lung (human) RGD PMID:30280776 RGD:126925764 NCBI chr 1:197,730,698...197,733,374
Ensembl chr 1:197,730,698...197,733,134
JBrowse link
G Hdac3 histone deacetylase 3 ISO RGD PMID:24482232 RGD:9588265 NCBI chr18:29,770,637...29,789,850
Ensembl chr18:29,770,636...29,793,856
JBrowse link
G Hes1 hes family bHLH transcription factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21994468 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:30381462 PMID:21812995 RGD:10395382 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 ISO protein:increased expression:lung (human) RGD PMID:20716340 RGD:9999189 NCBI chr 7:134,375,318...134,381,610
Ensembl chr 7:134,375,150...134,381,609
JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 susceptibility ISO antibody 703D4 recognizes Hnrnpa2b1 protein (RGD:9685415);protein:increased expression:sputum (human) RGD PMID:2846790 RGD:9685413 NCBI chr 4:80,534,659...80,545,297
Ensembl chr 4:80,534,651...80,545,249
JBrowse link
G Hras HRas proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Non-small cell lung carcinoma ClinVar PMID:2674130 PMID:3004741 PMID:3283542 PMID:3304147 PMID:6287572 More... NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
JBrowse link
G Hs3st2 heparan sulfate-glucosamine 3-sulfotransferase 2 ISO DNA:hypermethylation RGD PMID:27777637 RGD:152998954 NCBI chr 1:175,956,161...176,077,400
Ensembl chr 1:175,956,157...176,077,399
JBrowse link
G Htra1 HtrA serine peptidase 1 exacerbates ISO protein:decreased expression:lung (human) RGD PMID:32878625 RGD:152975629 NCBI chr 1:185,497,815...185,547,380
Ensembl chr 1:185,497,735...185,547,379
JBrowse link
G Icam1 intercellular adhesion molecule 1 disease_progression ISO progression-free survival; protein:increased secretion:serum (human) RGD PMID:19949019 RGD:4145465 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 severity ISO DNA:SNP: (rs11540478) (human) RGD PMID:25576295 RGD:150340558 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
JBrowse link
G Ikzf2 IKAROS family zinc finger 2 exacerbates ISO protein:decreased expression:venous blood, lung, regulatory T cell (human) RGD PMID:26460798 RGD:151347635 NCBI chr 9:71,042,440...71,191,296
Ensembl chr 9:71,042,440...71,190,867
JBrowse link
G Ikzf3 IKAROS family zinc finger 3 exacerbates ISO protein:increased expression:lung (human) RGD PMID:24823637 RGD:151347636 NCBI chr10:83,460,564...83,553,591
Ensembl chr10:83,465,745...83,553,591
JBrowse link
G Il10 interleukin 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20471133 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il18 interleukin 18 ISO protein:increased expression:serum RGD PMID:15955140 RGD:4889836 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il1a interleukin 1 alpha ISO DNA:SNPs: : RGD PMID:19505916 RGD:4142793 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta susceptibility ISO DNA:polymorphism: :-31T>C (human) RGD PMID:16126303 RGD:4143167 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1rn interleukin 1 receptor antagonist susceptibility ISO DNA:polymorphism (human) RGD PMID:16126303 RGD:4143167 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
JBrowse link
G Il6r interleukin 6 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:22552503 NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536
JBrowse link
G Il7 interleukin 7 disease_progression ISO RGD PMID:21159243 RGD:151347686 NCBI chr 2:94,235,219...94,280,075
Ensembl chr 2:94,234,766...94,280,075
JBrowse link
G Il7r interleukin 7 receptor disease_progression
susceptibility
ISO DNA:SNPs:: rs1494555,rs7737000(human) RGD PMID:21159243 PMID:19505916 RGD:151347686, RGD:4142793 NCBI chr 2:58,452,393...58,477,757
Ensembl chr 2:58,454,217...58,477,757
JBrowse link
G Irf1 interferon regulatory factor 1 ISO ClinVar Annotator: match by term: Non-small cell lung carcinoma ClinVar
RGD
PMID:10395927 PMID:10395927 RGD:1600014 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
JBrowse link
G Irs4 insulin receptor substrate 4 ISO protein:increased expression:lung (human) RGD PMID:33894221 RGD:151347872 NCBI chr  X:105,344,016...105,359,985 JBrowse link
G Itgb1 integrin subunit beta 1 ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:lung
CTD
RGD
PMID:21478906 PMID:28537888 RGD:13792830 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
JBrowse link
G Itgb3 integrin subunit beta 3 ISO RGD PMID:19386436 RGD:5037228 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
JBrowse link
G Itgb4 integrin subunit beta 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27107458 NCBI chr10:101,206,657...101,243,012
Ensembl chr10:101,206,665...101,243,012
JBrowse link
G Jak1 Janus kinase 1 disease_progression ISO protein:increased phosphorylation:lung RGD PMID:28989534 RGD:150524360 NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926
JBrowse link
G Jak2 Janus kinase 2 treatment ISO human cells in mouse model RGD PMID:25869210 PMID:21325979 RGD:149735332, RGD:149735342 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit severity ISO RNA:increased expression:lung (human) RGD PMID:29895215 RGD:151347665 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
JBrowse link
G Kat2a lysine acetyltransferase 2A disease_progression ISO RGD PMID:23543735 RGD:9590260 NCBI chr10:85,632,216...85,640,561
Ensembl chr10:85,632,216...85,640,166
JBrowse link
G Kdm1a lysine demethylase 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:22493729 NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319
JBrowse link
G Kdm2a lysine demethylase 2A severity ISO mRNA:increased expression:stomach (human)
human gene in a mouse model
RGD PMID:24200691 PMID:24482232 RGD:9588263, RGD:9588265 NCBI chr 1:201,612,427...201,682,359
Ensembl chr 1:201,612,453...201,680,787
JBrowse link
G Kdm3b lysine demethylase 3B ISO DNA:amplification:lung, peripheral blood mononuclear cell (human) RGD PMID:18975135 RGD:9586737 NCBI chr18:26,380,859...26,436,701
Ensembl chr18:26,380,964...26,436,628
JBrowse link
G Kdm5a lysine demethylase 5A severity ISO protein:increased expression:lung (human) RGD PMID:25162518 RGD:9588530 NCBI chr 4:153,565,909...153,643,912
Ensembl chr 4:153,565,846...153,642,422
JBrowse link
G Kdm6a lysine demethylase 6A exacerbates ISO human cells in a mouse model RGD PMID:32879445 RGD:150429731 NCBI chr  X:4,337,466...4,477,100
Ensembl chr  X:4,337,750...4,477,062
JBrowse link
G Kdr kinase insert domain receptor disease_progression
treatment
ISO DNA:CNVs
protein:increased expression:plasma
DNA:SNP:promoter:���906T>C (rs2071559) (human)
DNA, protein:CNVs, increased expression:lung
RGD PMID:21724587 PMID:21481963 PMID:25975224 PMID:12415261 PMID:16697074 More... RGD:126908001, RGD:126925199, RGD:126925198, RGD:126925192, RGD:126925189, RGD:126925188 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22684020 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
JBrowse link
G Kif5b kinesin family member 5B ISO CTD Direct Evidence: marker/mechanism CTD PMID:21757253 NCBI chr17:51,489,873...51,527,508
Ensembl chr17:51,489,944...51,527,508
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Non-small cell lung carcinoma
CTD
ClinVar
PMID:7530509 PMID:9438854 PMID:11276010 PMID:15790786 PMID:16731599 More... NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
JBrowse link
G Kmt2c lysine methyltransferase 2C disease_progression ISO RGD PMID:33665490 RGD:150523771 NCBI chr 4:9,620,638...9,834,787
Ensembl chr 4:9,609,627...9,833,539
JBrowse link
G Kmt2d lysine methyltransferase 2D disease_progression ISO DNA, protein:missense mutations, nonsense mutations, frameshift mutation, increased expression:lung RGD PMID:29627316 PMID:33665490 PMID:25112956 RGD:150523767, RGD:150523771, RGD:150523769 NCBI chr 7:129,980,744...130,022,088
Ensembl chr 7:129,962,887...130,020,325
JBrowse link
G Kras KRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Non-small cell lung cancer | ClinVar Annotator: match by term: Non-small cell lung carcinoma
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
RGD
PMID:2278970 PMID:2547513 PMID:3122217 PMID:3627975 PMID:6320174 More... RGD:5133242 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G L1cam L1 cell adhesion molecule disease_progression ISO RGD PMID:22307136 RGD:11570503 NCBI chr  X:151,597,270...151,623,776
Ensembl chr  X:151,597,277...151,623,857
JBrowse link
G Lamb3 laminin subunit beta 3 ISO mRNA:increased expression:lung: RGD PMID:10964684 RGD:13793368 NCBI chr13:104,833,810...104,875,405
Ensembl chr13:104,833,873...104,875,405
JBrowse link
G Lamc2 laminin subunit gamma 2 disease_progression ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:lung:
CTD
RGD
PMID:30381462 PMID:26180921 PMID:10964684 RGD:13793367, RGD:13793368 NCBI chr13:65,284,664...65,344,200
Ensembl chr13:65,284,664...65,344,200
JBrowse link
G Lep leptin ISO protein:increased expression:serum RGD PMID:19033693 RGD:5128815 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lgals1 galectin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17094902 NCBI chr 7:110,485,239...110,488,345
Ensembl chr 7:110,481,392...110,488,345
JBrowse link
G Lrp1b LDL receptor related protein 1B ameliorates ISO DNA:mutations:multiple: (human) RGD PMID:31164891 RGD:150429775 NCBI chr 3:24,594,302...26,715,037
Ensembl chr 3:24,594,991...26,715,505
JBrowse link
G Lrrc56 leucine rich repeat containing 56 ISO ClinVar Annotator: match by term: Non-small cell lung carcinoma ClinVar PMID:2674130 PMID:3004741 PMID:3283542 PMID:3304147 PMID:6287572 More... NCBI chr 1:196,299,843...196,315,170
Ensembl chr 1:196,299,846...196,315,172
JBrowse link
G Lrrc59 leucine rich repeat containing 59 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr10:79,572,295...79,586,953
Ensembl chr10:79,572,317...79,602,533
JBrowse link
G Lta lymphotoxin alpha ISO protein:increased expression:lung RGD PMID:9669810 RGD:4143264 NCBI chr20:3,618,853...3,621,324
Ensembl chr20:3,618,853...3,620,859
JBrowse link
G Ltf lactotransferrin ISO RGD PMID:21532506 RGD:7243860 NCBI chr 8:110,999,948...111,022,795
Ensembl chr 8:110,999,948...111,022,795
JBrowse link
G Macir macrophage immunometabolism regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr 9:98,420,760...98,440,818
Ensembl chr 9:98,420,376...98,441,733
JBrowse link
G Manf mesencephalic astrocyte-derived neurotrophic factor susceptibility ISO RGD PMID:8971156 RGD:1599219 NCBI chr 8:107,500,856...107,551,595
Ensembl chr 8:107,548,352...107,551,438
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 ameliorates ISO ClinVar Annotator: match by term: Non-small cell lung carcinoma ClinVar
RGD
PMID:7651428 PMID:17704260 PMID:18060073 PMID:18632602 PMID:19411838 More... RGD:5133242, RGD:150530476, RGD:5133243 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 ameliorates ISO RGD PMID:21514245 RGD:150530476 NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243
JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 ameliorates ISO associated with Postoperative Complications;DNA:SNP:intron: (rs12452497)(human) RGD PMID:26165383 RGD:11521299 NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993
JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 severity ISO DNA:SNPs:5'-UTR, intron 1: (rs17661089, rs16886403, rs726501) (human) RGD PMID:21636554 RGD:150573805 NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463
JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 disease_progression ISO RGD PMID:28393206 PMID:23533274 RGD:151356965, RGD:151356978 NCBI chr17:53,382,908...53,403,216
Ensembl chr17:53,383,131...53,403,216
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member disease_progression
ameliorates
severity
ISO protein:increased expression:lung, cytoplasm (human)
human cells in mouse model
protein:increased expression:lung (human)
DNA:mutations:multiple
RGD PMID:24469836 PMID:31662324 PMID:32945371 PMID:29567880 PMID:32276600 More... RGD:151356906 RGD:151356915 RGD:151356931, RGD:151356750, RGD:151357000, RGD:151356758 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Mdm2 MDM2 proto-oncogene ISO CTD Direct Evidence: marker/mechanism CTD PMID:19941079 PMID:21268124 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase disease_progression ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:21623265 PMID:21815704 PMID:22787409 PMID:24688052 PMID:20519133 More... RGD:5133241, RGD:13434906, RGD:5133243, RGD:5133242 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876
JBrowse link
G Mif macrophage migration inhibitory factor ISO RGD PMID:12576459 RGD:4891022 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
JBrowse link
G Mir107 microRNA 107 ISO mRNA:decreased expression:lung (human) RGD PMID:30280776 RGD:126925764 NCBI chr 1:232,337,767...232,337,853
Ensembl chr 1:232,337,767...232,337,853
JBrowse link
G Mir126b microRNA 126b ISO CTD Direct Evidence: therapeutic CTD PMID:20097187 NCBI chr 3:9,415,087...9,415,159 JBrowse link
G Mir145 microRNA 145 ISO CTD Direct Evidence: therapeutic CTD PMID:20097187 NCBI chr18:55,099,640...55,099,727
Ensembl chr18:55,099,640...55,099,727
JBrowse link
G Mir146a microRNA 146a ameliorates
severity
ISO RGD PMID:27494902 PMID:27494902 RGD:151665165, RGD:151665165 NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610
JBrowse link
G Mir154 microRNA 154 treatment
disease_progression
ISO human cells in mouse model
RNA:decreased expression:lung (human)
RGD PMID:30780105 PMID:25846246 RGD:152995466, RGD:152995468 NCBI chr 6:128,752,947...128,753,030
Ensembl chr 6:128,752,947...128,753,030
JBrowse link
G Mir205 microRNA 205 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21563230 NCBI chr13:105,035,878...105,035,985
Ensembl chr13:105,035,878...105,035,985
JBrowse link
G Mir21 microRNA 21 disease_progression ISO RNA:increased expression:lung (human)
RNA:increased expression:blood serum (human)
RGD PMID:20956945 PMID:20223231 PMID:25477028 PMID:22956424 PMID:33467964 More... RGD:41404697, RGD:152998901, RGD:152998899, RGD:152998889, RGD:152998886, RGD:152998885 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
JBrowse link
G Mir222 microRNA 222 disease_progression ISO RGD PMID:24955421 PMID:30233216 RGD:151708732, RGD:151708743 NCBI chr  X:3,428,904...3,429,006
Ensembl chr  X:3,428,904...3,429,006
JBrowse link
G Mir223 microRNA 223 severity
treatment
ISO RGD PMID:29615147 PMID:29615147 RGD:21408562, RGD:21408562 NCBI chr  X:61,141,887...61,141,996
Ensembl chr  X:61,141,887...61,141,996
JBrowse link
G Mir29a microRNA 29a ISO CTD Direct Evidence: marker/mechanism CTD PMID:22048643 NCBI chr 4:59,650,608...59,650,695 JBrowse link
G Mir29b1 microRNA 29b-1 treatment ISO RGD PMID:23591808 RGD:13464324 NCBI chr 4:59,650,987...59,651,067
Ensembl chr 4:59,650,986...59,651,067
JBrowse link
G Mir30c1 microRNA 30c-1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20889907 NCBI chr 5:134,349,237...134,349,325
Ensembl chr 5:134,349,237...134,349,325
JBrowse link
G Mir31 microRNA 31 ISO miRNA:increased expression:sputum (human) RGD PMID:27777637 RGD:152998954 NCBI chr 5:103,599,038...103,599,143 JBrowse link
G Mir346 microRNA 346 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27777383 NCBI chr16:10,218,118...10,218,215
Ensembl chr16:10,218,118...10,218,215
JBrowse link
G Mir377 microRNA 377 ISO miRNA:decreased expression:lung RGD PMID:27874949 RGD:13464321 NCBI chr 6:128,755,051...128,755,122 JBrowse link
G Mir381 microRNA 381 treatment ISO RGD PMID:29287202 RGD:13464271 NCBI chr 6:128,740,976...128,741,036 JBrowse link
G Mir484 microRNA 484 disease_progression ISO mRNA:increased expression:lung
mRNA:decreased expression:lung
RGD PMID:28982084 PMID:28982084 RGD:13703106, RGD:13703106 NCBI chr10:887,684...887,760
Ensembl chr10:887,684...887,760
JBrowse link
G Mir497 microRNA 497 ISO miRNA:decreased expression:lung RGD PMID:31115562 RGD:126925181 NCBI chr10:54,951,514...54,951,582
Ensembl chr10:54,951,505...54,951,584
JBrowse link
G Mir665 microRNA 665 disease_progression ISO associated with metastasis; mRNA:increased expression:lung (human) RGD PMID:32269632 PMID:32269632 RGD:151361291, RGD:151361291 NCBI chr 6:128,539,440...128,539,533
Ensembl chr 6:128,539,440...128,539,533
JBrowse link
G Mir671 microRNA 671 severity ISO RGD PMID:30664171 RGD:151665171 NCBI chr 4:10,580,747...10,580,827
Ensembl chr 4:10,580,738...10,580,835
JBrowse link
G Mki67 marker of proliferation Ki-67 ameliorates ISO human cells in mouse model RGD PMID:32276600 RGD:151357000 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Mlh1 mutL homolog 1 severity ISO RGD PMID:32211850 PMID:18370958 RGD:126848780, RGD:126848801 NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617
JBrowse link
G Mmp1 matrix metallopeptidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20471133 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
JBrowse link
G Mmp11 matrix metallopeptidase 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10741738 NCBI chr20:12,730,846...12,739,629
Ensembl chr20:12,730,836...12,739,628
JBrowse link
G Mmp2 matrix metallopeptidase 2 severity ISO protein:increased expression, increased activity:lung RGD PMID:17143501 RGD:5130739 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp7 matrix metallopeptidase 7 ISO mRNA:increased expression:lung RGD PMID:19596921 RGD:5129528 NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902
JBrowse link
G Mmp9 matrix metallopeptidase 9 disease_progression ISO protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:21789004 PMID:20704821 RGD:5129215 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Ms4a1 membrane spanning 4-domains A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22514692 NCBI chr 1:207,906,370...207,927,028
Ensembl chr 1:207,906,374...207,918,512
JBrowse link
G Msh2 mutS homolog 2 treatment ISO protein:decreased expression:lung
DNA:SNP: :rs6544991 (human)
RGD PMID:32211850 PMID:20458443 PMID:16783774 PMID:20145178 PMID:28093084 RGD:126848780, RGD:126848800, RGD:126848791, RGD:126848789, RGD:126848786 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938
JBrowse link
G Msh3 mutS homolog 3 treatment ISO DNA:SNPs: :rs6151627, rs6151670, rs7709909 (human) RGD PMID:28093084 RGD:126848786 NCBI chr 2:23,444,326...23,585,777 JBrowse link
G Msh5 mutS homolog 5 treatment ISO DNA:SNPs: :rs805304, rs707939 (human) RGD PMID:28093084 RGD:126848786 NCBI chr20:3,773,867...3,793,337
Ensembl chr20:3,776,942...3,793,336
JBrowse link
G Mt3 metallothionein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17043644 NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158
JBrowse link
G Mtor mechanistic target of rapamycin kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:24688052 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor disease_progression ISO protein:increased expression:lung (human)
DNA:hypomethylation:promoter (human)
RGD PMID:31432177 PMID:32010578 RGD:150519919, RGD:150524328 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
JBrowse link
G Nat1 N-acetyltransferase 1 susceptibility ISO DNA:polymorphism: : RGD PMID:18258609 RGD:4140950 NCBI chr16:22,218,217...22,238,516
Ensembl chr16:22,208,194...22,238,520
JBrowse link
G Ncaph non-SMC condensin I complex, subunit H ISO protein:decreased expression:lung (human) RGD PMID:32945371 RGD:151356931 NCBI chr 3:114,371,937...114,399,223
Ensembl chr 3:114,371,941...114,399,180
JBrowse link
G Ncoa2 nuclear receptor coactivator 2 ISO DNA:SNPs:introns: (rs2926702, rs11993276) (human) RGD PMID:23144319 RGD:153002581 NCBI chr 5:5,835,642...6,069,693
Ensembl chr 5:5,835,706...6,067,451
JBrowse link
G Ncoa3 nuclear receptor coactivator 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20852035 NCBI chr 3:154,738,566...154,821,395
Ensembl chr 3:154,738,581...154,818,594
JBrowse link
G Ndc80 NDC80 kinetochore complex component disease_progression ISO RGD PMID:17079454 RGD:28867236 NCBI chr 9:111,407,191...111,440,921
Ensembl chr 9:111,407,191...111,440,924
JBrowse link
G Ndrg1 N-myc downstream regulated 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15341671 NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880
JBrowse link
G Nek2 NIMA-related kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28509438 NCBI chr13:103,405,818...103,419,063
Ensembl chr13:103,405,819...103,419,051
JBrowse link
G Nf1 neurofibromin 1 ISO mRNA:increased expression:lung (human) RGD PMID:30280776 RGD:126925764 NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658
JBrowse link
G Nf2 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor ISO RGD PMID:21743150 RGD:150530639 NCBI chr14:79,627,399...79,710,709
Ensembl chr14:79,627,399...79,710,667
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22684020 PMID:26482881 PMID:33148531 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 susceptibility ISO DNA:polymorphism:rs28362491(human)
protein:increased expression:nucleus
RGD PMID:26221384 PMID:17899287 RGD:13793390, RGD:13793391 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nnat neuronatin ISO CTD Direct Evidence: marker/mechanism CTD PMID:17043644 NCBI chr 3:146,225,941...146,228,868
Ensembl chr 3:146,226,407...146,228,834
JBrowse link
G Notch1 notch receptor 1 ISO ClinVar Annotator: match by term: Non-small cell lung carcinoma ClinVar PMID:20007775 PMID:25741868 PMID:28492532 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
JBrowse link
G Notch3 notch receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21994468 NCBI chr 7:11,132,984...11,184,025
Ensembl chr 7:11,133,706...11,184,025
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 disease_progression ISO DNA:polymorphism: :
CTD Direct Evidence: marker/mechanism
DNA:polymorphism:cds: 609 C>T (human)
CTD
RGD
PMID:9865924 PMID:21479364 PMID:21479364 PMID:19596483 RGD:5133265, RGD:5133268 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 disease_progression ISO protein:increased expression:lung RGD PMID:16806572 RGD:4892333 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Nras NRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Non-small cell lung cancer | ClinVar Annotator: match by term: Non-small cell lung carcinoma ClinVar PMID:1654209 PMID:2278970 PMID:2674680 PMID:3122217 PMID:6587382 More... NCBI chr 2:190,582,885...190,593,509
Ensembl chr 2:190,582,918...190,591,626
JBrowse link
G Nrp1 neuropilin 1 disease_progression ISO DNA, protein:CNVs, increased expression:lung RGD PMID:25561764 RGD:126925188 NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633
JBrowse link
G Nuf2 NUF2 component of NDC80 kinetochore complex disease_progression ISO RGD PMID:17079454 RGD:28867236 NCBI chr13:81,693,675...81,722,765
Ensembl chr13:81,693,598...81,722,766
JBrowse link
G Osmr oncostatin M receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:15496427 NCBI chr 2:55,907,119...55,961,373
Ensembl chr 2:55,907,132...55,961,262
JBrowse link
G Oxtr oxytocin receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:17043644 NCBI chr 4:145,598,549...145,614,674
Ensembl chr 4:145,599,561...145,614,674
JBrowse link
G Paox polyamine oxidase susceptibility ISO DNA:SNPs: :rs7316, rs1046175(human) RGD PMID:31016788 RGD:151667418 NCBI chr 1:194,903,267...194,928,504
Ensembl chr 1:194,903,273...194,928,504
JBrowse link
G Pbrm1 polybromo 1 disease_progression ISO RGD PMID:32195359 RGD:150340625 NCBI chr16:6,213,507...6,312,895
Ensembl chr16:6,213,300...6,311,780
JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 disease_progression ISO mRNA:increased expression:blood serum RGD PMID:25064732 RGD:13503320 NCBI chr10:13,105,435...13,182,664
Ensembl chr10:13,105,498...13,174,623
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 treatment ISO human cells in mouse model RGD PMID:23632475 RGD:150404268 NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116
JBrowse link
G Pgam1 phosphoglycerate mutase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17094902 NCBI chr 1:240,723,832...240,731,443
Ensembl chr 1:240,723,920...240,738,452
JBrowse link
G Phgdh phosphoglycerate dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:26482881 NCBI chr 2:185,906,964...185,936,160
Ensembl chr 2:185,906,966...185,935,944
JBrowse link
G Phlda2 pleckstrin homology-like domain, family A, member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15496427 NCBI chr 1:198,696,897...198,699,292
Ensembl chr 1:198,696,897...198,697,836
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha ISO ClinVar Annotator: match by term: Non-small cell lung cancer | ClinVar Annotator: match by term: Non-small cell lung carcinoma ClinVar
RGD
PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 More... RGD:5133243, RGD:5133242 NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
JBrowse link
G Plau plasminogen activator, urokinase ISO RGD PMID:20937265 RGD:4892055 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
JBrowse link
G Plbd1 phospholipase B domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15496427 NCBI chr 4:169,472,983...169,529,277
Ensembl chr 4:169,472,983...169,529,277
JBrowse link
G Plcg1 phospholipase C, gamma 1 treatment ISO human cell line in a mouse model RGD PMID:33928024 RGD:151665816 NCBI chr 3:149,385,587...149,416,330
Ensembl chr 3:149,385,587...149,416,330
JBrowse link
G Pole DNA polymerase epsilon, catalytic subunit ameliorates ISO DNA:mutations:multiple (human) RGD PMID:32433714 RGD:151347639 NCBI chr12:46,345,420...46,393,984
Ensembl chr12:46,345,420...46,393,939
JBrowse link
G Ppia peptidylprolyl isomerase A<