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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Respiratory Tract Neoplasms
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Accession:DOID:9003744 term browser browse the term
Definition:New abnormal growth of tissue in the RESPIRATORY SYSTEM.
Synonyms:exact_synonym: Respiratory Tract Neoplasm;   respiratory system neoplasm
 primary_id: MESH:D012142
 xref: EFO:0003853
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
adenosquamous lung carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ttr transthyretin ISO protein:increased expression:lung (human) RGD PMID:26943652 RGD:151665207 NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008 		JBrowse link
asbestos-related lung carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam28 ADAM metallopeptidase domain 28 ISO associated with lung adenocarcinoma ;mRNA:increased expression:lung RGD PMID:20544843 RGD:153298907 NCBI chr15:43,774,463...43,840,726
Ensembl chr15:42,944,467...43,840,672 		JBrowse link
G Kif5a kinesin family member 5A susceptibility ISO protein:increased expression:serum (human) RGD PMID:21231887 RGD:12793066 NCBI chr 7:63,051,894...63,089,024
Ensembl chr 7:63,049,424...63,092,858 		JBrowse link
G Rarb retinoic acid receptor, beta ISO DNA:hypomethylation:lung RGD PMID:28722770 RGD:13503322 NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288 		JBrowse link
bronchiolo-alveolar adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alx4 ALX homeobox 4 ameliorates ISO RGD PMID:24037716 RGD:153344522 NCBI chr 3:79,611,682...79,648,260
Ensembl chr 3:79,611,719...79,648,260 		JBrowse link
G Ccnd1 cyclin D1 ISO protein:increased expression:lung RGD PMID:14674039 RGD:13434930 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Dnmt1 DNA methyltransferase 1 disease_progression ISO RGD PMID:19484794 RGD:4140940 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659 		JBrowse link
G Egfr epidermal growth factor receptor ISO
IMP		 protein:increased expression:tumor (human)
DNA:mutations:exons:
DNA:snp:cds:p.T790M (human)		 RGD PMID:21419590 PMID:26059825 PMID:15737014 RGD:5131630, RGD:11075076, RGD:5131465 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Egr1 early growth response 1 ISO mRNA:decreased expression:tumor (human) RGD PMID:11948124 RGD:5131942 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 ISO DNA:hypermethylation:promoter (human) RGD PMID:19484794 RGD:4140940 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Kras KRAS proto-oncogene, GTPase IMP DNA:mutations:cds: RGD PMID:26059825 RGD:11075076 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Mir130a microRNA 130a ISO CTD Direct Evidence: marker/mechanism CTD PMID:25926378 NCBI chr 3:69,822,542...69,822,629
Ensembl chr 3:69,822,542...69,822,629 		JBrowse link
G Mir144 microRNA 144 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25926378 NCBI chr10:62,961,348...62,961,430
Ensembl chr10:62,961,348...62,961,430 		JBrowse link
G Mir19a microRNA 19a ISO CTD Direct Evidence: marker/mechanism CTD PMID:25926378 NCBI chr15:92,180,912...92,180,993
Ensembl chr15:92,180,912...92,180,993 		JBrowse link
G Mir345 microRNA 345 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25926378 NCBI chr 6:127,754,027...127,754,122
Ensembl chr 6:127,754,027...127,754,122 		JBrowse link
G Mir497 microRNA 497 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25926378 NCBI chr10:54,951,514...54,951,582
Ensembl chr10:54,951,505...54,951,584 		JBrowse link
G Tp53 tumor protein p53 IMP DNA:mutations:exons: RGD PMID:26059825 RGD:11075076 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
bronchus carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gstp1 glutathione S-transferase pi 1 ISO mRNA:decreased expression:bronchus, epithelial cell RGD PMID:10749130 RGD:4142527 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO protein:increased secretion:lung (human) RGD PMID:18764914 RGD:4145523 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Il10 interleukin 10 ISO protein:increased expression:lung RGD PMID:8030748 RGD:4143231 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO protein:increased expression, alternative forms:lung RGD PMID:8030748 RGD:4143231 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445 		JBrowse link
Carney Triad term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sdha succinate dehydrogenase complex flavoprotein subunit A ISO ClinVar Annotator: match by term: Carney triad ClinVar PMID:20484225 PMID:21505157 PMID:21752896 PMID:22955521 PMID:22974104 More... NCBI chr 1:28,935,965...28,960,936
Ensembl chr 1:28,940,164...28,961,535 		JBrowse link
G Sdhb succinate dehydrogenase complex iron sulfur subunit B ISO ClinVar Annotator: match by term: GASTRIC LEIOMYOSARCOMA, PULMONARY CHONDROMA, AND EXTRAADRENAL PARAGANGLIOMA ClinVar PMID:15987702 PMID:16288654 PMID:16317055 PMID:16912137 PMID:16916404 More... NCBI chr 5:153,264,906...153,285,570
Ensembl chr 5:153,264,899...153,314,293 		JBrowse link
G Sdhc succinate dehydrogenase complex subunit C ISO ClinVar Annotator: match by term: Carney triad | ClinVar Annotator: match by term: GASTRIC LEIOMYOSARCOMA, PULMONARY CHONDROMA, AND EXTRAADRENAL PARAGANGLIOMA ClinVar PMID:9536098 PMID:12658451 PMID:17576681 PMID:17667967 PMID:17804857 More... NCBI chr13:83,544,652...83,565,560
Ensembl chr13:83,544,652...83,566,253 		JBrowse link
DICER1 syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asb2 ankyrin repeat and SOCS box-containing 2 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:122,474,754...122,511,014
Ensembl chr 6:122,474,756...122,510,854 		JBrowse link
G Btbd7 BTB domain containing 7 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:121,920,365...122,010,114
Ensembl chr 6:121,923,023...121,972,405 		JBrowse link
G Cox8c cytochrome c oxidase subunit 8C ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:122,028,566...122,029,889
Ensembl chr 6:122,028,566...122,029,889 		JBrowse link
G Ddx24 DEAD-box helicase 24 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:122,564,767...122,582,032
Ensembl chr 6:122,564,767...122,581,927 		JBrowse link
G Dicer1 dicer 1 ribonuclease III ISO ClinVar Annotator: match by term: DICER1 syndrome OMIM
ClinVar		 PMID:9295070 PMID:9345104 PMID:9536098 PMID:15242644 PMID:15987463 More... NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965 		JBrowse link
G Fam181a family with sequence similarity 181, member A ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:122,465,373...122,471,397
Ensembl chr 6:122,465,391...122,471,397 		JBrowse link
G Gsc goosecoid homeobox ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:123,388,072...123,390,111
Ensembl chr 6:123,388,072...123,390,111 		JBrowse link
G Ifi27 interferon, alpha-inducible protein 27 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:122,590,461...122,596,996
Ensembl chr 6:122,590,472...122,779,294 		JBrowse link
G Ifi27l2b interferon, alpha-inducible protein 27 like 2B ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:122,598,872...122,600,358
Ensembl chr 6:122,598,872...122,600,360 		JBrowse link
G Otub2 OTU deubiquitinase, ubiquitin aldehyde binding 2 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:122,545,029...122,563,651
Ensembl chr 6:122,545,061...122,563,644 		JBrowse link
G Ppp4r4 protein phosphatase 4, regulatory subunit 4 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:122,663,172...122,753,988
Ensembl chr 6:122,663,344...122,753,384 		JBrowse link
G Prima1 proline rich membrane anchor 1 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:122,338,365...122,390,955
Ensembl chr 6:122,338,370...122,389,921 		JBrowse link
G Serpina1 serpin family A member 1 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:122,866,314...122,888,339
Ensembl chr 6:122,866,312...122,888,339 		JBrowse link
G Serpina10 serpin family A member 10 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:122,756,106...122,764,544
Ensembl chr 6:122,756,108...122,764,544 		JBrowse link
G Serpina11 serpin family A member 11 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:122,903,246...122,912,695
Ensembl chr 6:122,903,250...122,912,670 		JBrowse link
G Serpina12 serpin family A member 12 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:122,952,552...122,967,271
Ensembl chr 6:122,952,552...122,967,271 		JBrowse link
G Serpina1f serpin family A member 1F ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:122,820,752...122,827,112
Ensembl chr 6:122,820,907...122,827,112 		JBrowse link
G Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:123,323,632...123,331,166
Ensembl chr 6:123,323,629...123,332,433 		JBrowse link
G Serpina4 serpin family A member 4 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:122,999,970...123,009,083
Ensembl chr 6:122,999,900...123,009,082 		JBrowse link
G Serpina5 serpin family A member 5 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:123,009,224...123,028,412
Ensembl chr 6:123,023,306...123,028,407 		JBrowse link
G Serpina6 serpin family A member 6 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:122,780,040...122,790,274
Ensembl chr 6:122,780,043...122,790,349 		JBrowse link
G Serpina9 serpin family A member 9 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:122,918,819...122,936,000
Ensembl chr 6:122,918,880...122,936,000 		JBrowse link
G Ubr7 ubiquitin protein ligase E3 component n-recognin 7 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:121,898,613...121,918,480
Ensembl chr 6:121,898,623...121,918,477 		JBrowse link
G Unc79 unc-79 homolog, NALCN channel complex subunit ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:122,082,369...122,327,641
Ensembl chr 6:122,080,308...122,327,591 		JBrowse link
glottis squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wrap53 WD repeat containing, antisense to TP53 disease_progression ISO RGD PMID:28849066 RGD:21081521 NCBI chr10:54,282,092...54,299,908
Ensembl chr10:54,282,105...54,298,929 		JBrowse link
large cell neuroendocrine carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc7a5 solute carrier family 7 member 5 disease_progression ISO RGD PMID:18440724 RGD:151361285 NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823 		JBrowse link
laryngeal carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ackr3 atypical chemokine receptor 3 disease_progression ISO protein:increased expression:larynx (human) RGD PMID:16494043 RGD:152025548 NCBI chr 9:90,799,682...90,811,246
Ensembl chr 9:90,799,686...90,811,237 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 disease_progression ISO protein:increased expression:larynx (human) RGD PMID:16494043 RGD:152025548 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883 		JBrowse link
G Kmt2c lysine methyltransferase 2C ISO mRNA:decreased expression:larynx RGD PMID:25633166 RGD:151356763 NCBI chr 4:9,620,638...9,834,787
Ensembl chr 4:9,609,627...9,833,539 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 severity ISO RGD PMID:20164024 RGD:150573814 NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383 		JBrowse link
G Traf6 TNF receptor associated factor 6 disease_progression ISO RGD PMID:20164024 RGD:150573814 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
G Ubr5 ubiquitin protein ligase E3 component n-recognin 5 exacerbates ISO mRNA, protein:increased expression:larynx (human) RGD PMID:32468011 RGD:151665191 NCBI chr 7:69,116,758...69,224,490
Ensembl chr 7:69,116,761...69,224,903 		JBrowse link
G Xrcc1 X-ray repair cross complementing 1 susceptibility ISO DNA:SNPs, haplotype:: (rs3213403, rs1799778, rs3213282) (human)
DNA:missense mutation:cds: p.R280H (human)		 RGD PMID:24956286 PMID:27808358 RGD:151236314, RGD:151236313 NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701 		JBrowse link
Laryngeal Neoplasms term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:18500343 NCBI chr 2:226,748,724...226,763,183
Ensembl chr 2:226,741,788...226,763,182 		JBrowse link
G Egfr epidermal growth factor receptor severity ISO protein:increased expression:tumor (human) RGD PMID:8883413 RGD:5131485 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit susceptibility ISO DNA:snp:exon:c.354T>C (human) (rs11615) RGD PMID:24582975 RGD:13207310 NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 ISO protein:increased expression:larynx RGD PMID:18335753 RGD:4140949 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Mir10a microRNA 10a sexual_dimorphism ISO miRNA:decreased expression:larynx epithelium (human) RGD PMID:25266939 RGD:153344531 NCBI chr10:81,283,171...81,283,280
Ensembl chr10:81,283,171...81,283,280 		JBrowse link
G Mir34c microRNA 34c sexual_dimorphism ISO miRNA:increased expression:larynx epithelium (human) RGD PMID:25266939 RGD:153344531 NCBI chr 8:51,409,726...51,409,802
Ensembl chr 8:51,409,726...51,409,802 		JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO RGD PMID:17786346 RGD:5130203 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Nat1 N-acetyltransferase 1 susceptibility ISO DNA:polymorphism: : RGD PMID:12037388 RGD:5131864 NCBI chr16:22,218,217...22,238,516
Ensembl chr16:22,208,194...22,238,520 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 severity ISO protein:increased expression:larynx RGD PMID:20429377 RGD:5135434 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Spp1 secreted phosphoprotein 1 ISO RGD PMID:16299231 RGD:1581365 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
Laryngeal Papillomatosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO RGD PMID:19736197 RGD:5135499 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N ISO protein:decreased expression:serum RGD PMID:16273852 RGD:5147435 NCBI chr 6:123,323,632...123,331,166
Ensembl chr 6:123,323,629...123,332,433 		JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member ISO RGD PMID:10618282 RGD:5147846 NCBI chr20:4,656,262...4,666,634
Ensembl chr20:4,656,263...4,666,901 		JBrowse link
laryngeal squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase ISO protein:decreased activity:larynx RGD PMID:8138195 RGD:152995273 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088 		JBrowse link
G Cat catalase ISO protein:increased activity:larynx RGD PMID:8138195 RGD:152995273 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cdc73 cell division cycle 73 disease_progression ISO protein:decreased expression:larynx (human) RGD PMID:27334641 RGD:150539447 NCBI chr13:55,357,226...55,449,690
Ensembl chr13:55,357,226...55,449,656 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A ISO RGD PMID:15646812 RGD:8662837 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Chd4 chromodomain helicase DNA binding protein 4 exacerbates ISO mRNA:increased expression:larynx (human) RGD PMID:33315534 RGD:153323310 NCBI chr 4:157,898,503...157,931,632
Ensembl chr 4:157,899,391...157,931,541 		JBrowse link
G Egfr epidermal growth factor receptor disease_progression ISO RGD PMID:22549618 RGD:126790474 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 disease_progression ISO RGD PMID:22549618 RGD:126790474 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078 		JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 disease_progression ISO RGD PMID:22549618 RGD:126790474 NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525 		JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 disease_progression ISO RGD PMID:22549618 RGD:126790474 NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595 		JBrowse link
G Foxl2 forkhead box L2 exacerbates ISO mRNA:increased expression:larynx (human) RGD PMID:32517588 RGD:151667913 NCBI chr 8:99,512,971...99,514,500
Ensembl chr 8:99,513,303...99,514,427 		JBrowse link
G Gpx1 glutathione peroxidase 1 disease_progression
no_association		 ISO protein:increased expression:larynx (human)
DNA:missense mutation:CDS:p.P198L (human)
DNA:missense mutation:CDS:p.P198L (rs1050450) (human)		 RGD PMID:28641905 PMID:24074040 PMID:27188866 RGD:152995454, RGD:152995493, RGD:152995455 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 severity ISO associated with Neoplasm Metastasis; protein:mRNA,increased expression:larynx epithelium (human) RGD PMID:19513509 RGD:150429781 NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993 		JBrowse link
G Mir10a microRNA 10a severity ISO miRNA:decreased expression:blood serum (human) RGD PMID:35117730 RGD:153344530 NCBI chr10:81,283,171...81,283,280
Ensembl chr10:81,283,171...81,283,280 		JBrowse link
G Mir136 microRNA 136 ISO RNA:decreased expression:larynx (human) RGD PMID:32014687 RGD:153344610 NCBI chr 6:128,549,096...128,549,177
Ensembl chr 6:128,549,096...128,549,177 		JBrowse link
G Mir21 microRNA 21 exacerbates ISO miRNA:increased expression:blood serum (human) RGD PMID:35117730 RGD:153344530 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mir31 microRNA 31 disease_progression ISO RNA:decreased expression:mucosa of larynx (human) RGD PMID:29737563 RGD:152998933 NCBI chr 5:103,599,038...103,599,143 JBrowse link
G Mlh1 mutL homolog 1 disease_progression ISO mRNA:decreased expression:larynx RGD PMID:23787767 RGD:126848783 NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617 		JBrowse link
G Mmp2 matrix metallopeptidase 2 ISO RGD PMID:17786346 RGD:5130203 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Msh2 mutS homolog 2 disease_progression ISO mRNA:decreased expression:larynx RGD PMID:23787767 RGD:126848783 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938 		JBrowse link
G Nat2 N-acetyltransferase 2 susceptibility ISO DNA:polymorphisms: : RGD PMID:19922706 PMID:16155914 RGD:5131602, RGD:5131856 NCBI chr16:22,207,362...22,238,513
Ensembl chr16:22,208,194...22,238,520 		JBrowse link
G Plcg1 phospholipase C, gamma 1 ameliorates ISO mRNA:increased expression:larynx (human) RGD PMID:33466212 RGD:151665160 NCBI chr 3:149,385,587...149,416,330
Ensembl chr 3:149,385,587...149,416,330 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit severity ISO associated with Neoplasm Metastasis; protein:mRNA,increased expression:larynx epithelium (human) RGD PMID:19513509 RGD:150429781 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Xdh xanthine dehydrogenase ISO protein:increased activity:larynx RGD PMID:8138195 RGD:152995273 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268 		JBrowse link
larynx cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cxcl12 C-X-C motif chemokine ligand 12 exacerbates ISO protein:increased expression: mucosa of larynx (human) RGD PMID:23259294 RGD:152177474 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 exacerbates ISO protein:increased expression: mucosa of larynx (human) RGD PMID:23259294 RGD:152177474 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883 		JBrowse link
G Ercc5 ERCC excision repair 5, endonuclease susceptibility ISO DNA:missense mutation:CDS:p.D1104H (human) RGD PMID:19444904 RGD:155260337 NCBI chr 9:46,309,477...46,354,478
Ensembl chr 9:46,309,389...46,354,472 		JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor susceptibility ISO DNA:missense mutation:CDS:p.R1230P (human) RGD PMID:19444904 RGD:155260337 NCBI chr16:7,764,983...7,835,587
Ensembl chr16:7,765,013...7,835,587 		JBrowse link
G Gpx1 glutathione peroxidase 1 susceptibility ISO DNA:missense mutation:CDS: (rs1050450) (human) RGD PMID:23516596 RGD:152998903 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 ISO DNA:deletion: : RGD PMID:19252926 RGD:4140943 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Gstm3 glutathione S-transferase mu 3 ISO RGD PMID:10067818 RGD:5135043 NCBI chr 2:195,590,450...195,612,578
Ensembl chr 2:195,607,289...195,612,475 		JBrowse link
G Gstm5 glutathione S-transferase, mu 5 ISO RGD PMID:10067818 RGD:5135043 NCBI chr 2:195,531,627...195,534,562
Ensembl chr 2:195,531,495...195,534,553 		JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 ameliorates ISO mRNA:increased expression:larynx (human) RGD PMID:32791689 RGD:155256869 NCBI chr12:2,591,312...2,604,211
Ensembl chr12:2,591,219...2,604,222 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 onset ISO DNA:insertion:Cds: 3020_3021insC (human) RGD PMID:20223031 RGD:5131515 NCBI chr19:18,379,720...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Vegfa vascular endothelial growth factor A treatment ISO RGD PMID:20967863 RGD:126925200 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
lung adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199 		JBrowse link
G Abce1 ATP binding cassette subfamily E member 1 severity ISO mRNA, protein:increased expression:lung (human) RGD PMID:18788636 RGD:11046260 NCBI chr19:28,205,566...28,230,489
Ensembl chr19:28,205,555...28,230,489 		JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr  X:105,942,794...106,006,573
Ensembl chr  X:105,942,799...106,006,427 		JBrowse link
G Adam28 ADAM metallopeptidase domain 28 disease_progression
treatment
exacerbates		 ISO protein:increased expression:lung RGD PMID:30190423 PMID:20112342 PMID:29882245 PMID:26800504 RGD:153297795, RGD:153297794, RGD:153297792, RGD:11531771 NCBI chr15:43,774,463...43,840,726
Ensembl chr15:42,944,467...43,840,672 		JBrowse link
G Ahcy adenosylhomocysteinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 3:143,569,134...143,584,359
Ensembl chr 3:143,569,094...143,584,393 		JBrowse link
G Ahr aryl hydrocarbon receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:12597446 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 disease_progression ISO RGD PMID:30727821 RGD:27226687 NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:17611497 PMID:18256540 PMID:18392055 PMID:18504432 PMID:18611285 More... NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Alb albumin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:239,375,657...239,407,967
Ensembl chr 1:239,375,669...239,407,890 		JBrowse link
G Aldoa aldolase, fructose-bisphosphate A ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182 		JBrowse link
G Alk ALK receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Lung adenocarcinoma		 CTD
ClinVar		 PMID:18923525 PMID:20979469 PMID:20979473 PMID:21030459 PMID:21575866 More... NCBI chr 6:22,879,653...23,599,636
Ensembl chr 6:22,880,625...23,598,034 		JBrowse link
G Alox12b arachidonate 12-lipoxygenase, 12R type ISO CTD Direct Evidence: marker/mechanism CTD PMID:30258081 NCBI chr10:53,863,060...53,874,938
Ensembl chr10:53,863,060...53,874,938 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:30258081 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743 		JBrowse link
G Alx4 ALX homeobox 4 disease_progression ISO RGD PMID:18978557 RGD:153350135 NCBI chr 3:79,611,682...79,648,260
Ensembl chr 3:79,611,719...79,648,260 		JBrowse link
G Anapc2 anaphase promoting complex subunit 2 severity ISO mRNA:decreased expression:lung (human) RGD PMID:12036940 RGD:14696682 NCBI chr 3:8,086,434...8,098,182
Ensembl chr 3:8,086,462...8,098,178 		JBrowse link
G Anp32a acidic nuclear phosphoprotein 32 family member A ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 Ensembl chr 8:62,827,456...62,865,443 JBrowse link
G Anxa1 annexin A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343 		JBrowse link
G Anxa5 annexin A5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369 		JBrowse link
G Apc APC regulator of WNT signaling pathway ISO ClinVar Annotator: match by term: Adenocarcinoma of lung ClinVar PMID:1316610 PMID:1338764 PMID:2281069 PMID:8187091 PMID:8381579 More... NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696 		JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785 		JBrowse link
G Apoa1 apolipoprotein A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G Apoc3 apolipoprotein C3 ISO protein:altered glycosylation:: RGD PMID:19322776 RGD:153344619 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583 		JBrowse link
G Aqp4 aquaporin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856 		JBrowse link
G Araf A-Raf proto-oncogene, serine/threonine kinase ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:24569458 PMID:26619011 NCBI chr  X:1,227,392...1,292,356
Ensembl chr  X:1,227,392...1,239,073 		JBrowse link
G Arg1 arginase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422 		JBrowse link
G Arhgap35 Rho GTPase activating protein 35 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr 1:77,202,436...77,319,298
Ensembl chr 1:77,202,436...77,319,298 		JBrowse link
G Atp5pd ATP synthase peripheral stalk subunit d ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr10:100,657,700...100,662,960
Ensembl chr10:100,657,708...100,663,479 		JBrowse link
G Atrx ATRX, chromatin remodeler disease_progression ISO RGD PMID:31374064 RGD:127285382 NCBI chr  X:70,850,981...70,997,330
Ensembl chr  X:70,850,981...70,997,330 		JBrowse link
G Axin2 axin 2 disease_progression
susceptibility		 ISO DNA:SNPs::1712 +19 G>A,148 C>T(human)
DNA:SNP:cds:p.P50S(human)		 RGD PMID:30346805 PMID:16820935 RGD:151356655, RGD:151356657 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231 		JBrowse link
G Azgp1 alpha-2-glycoprotein 1, zinc-binding ISO mRNA,protein:increased expression:lung RGD PMID:17724461 RGD:153350134 NCBI chr12:16,930,990...16,939,333
Ensembl chr12:16,931,024...16,939,091 		JBrowse link
G B2m beta-2 microglobulin ISO ClinVar Annotator: match by term: Adenocarcinoma of lung ClinVar PMID:26619011 NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766 		JBrowse link
G Bap1 Brca1 associated protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231345 NCBI chr16:6,446,709...6,455,535
Ensembl chr16:6,446,709...6,455,535 		JBrowse link
G Bhlhe41 basic helix-loop-helix family, member e41 ISO mRNA:decreased expression:lung (human) RGD PMID:18223678 RGD:151665316 NCBI chr 4:178,833,085...178,838,685
Ensembl chr 4:178,834,271...178,838,468 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 exacerbates ISO mRNA:increased expression:B cell (human) RGD PMID:33098370 RGD:153323293 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 disease_progression
ameliorates		 ISO mRNA:increased expression:lung (human) RGD PMID:31964418 RGD:153344516 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma		 CTD
ClinVar		 PMID:12068308 PMID:12198537 PMID:12447372 PMID:12460918 PMID:12460919 More... NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463 		JBrowse link
G Btk Bruton tyrosine kinase exacerbates
susceptibility		 ISO mRNA:decreased expression:lung (human) RGD PMID:31803536 PMID:32351880 RGD:151347849, RGD:151347848 NCBI chr  X:97,722,796...97,762,315
Ensembl chr  X:97,722,802...97,761,853 		JBrowse link
G Bzw2 basic leucine zipper and W2 domains 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 6:52,828,069...52,888,599
Ensembl chr 6:52,827,661...52,888,628 		JBrowse link
G Cadm1 cell adhesion molecule 1 IEP DNA, mRNA:hypermethylation, decreased expression:promoter:liver RGD PMID:16814249 RGD:2289096 NCBI chr 8:47,847,836...48,178,703
Ensembl chr 8:47,847,325...48,182,833 		JBrowse link
G Calr calreticulin treatment ISO human cells and recombinant gene in a mouse model RGD PMID:18245558 RGD:150521698 NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414 		JBrowse link
G Capg capping actin protein, gelsolin like ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr 4:104,594,743...104,611,856
Ensembl chr 4:104,594,753...104,611,856 		JBrowse link
G Cbx5 chromobox 5 disease_progression ISO mRNA,protein:increased expression:lung: RGD PMID:22900142 RGD:9586743 NCBI chr 7:134,333,165...134,376,102
Ensembl chr 7:134,331,335...134,375,022 		JBrowse link
G Cbx7 chromobox 7 ISO mRNA,DNA:decreased expression, loss of heterozygosity:lung: RGD PMID:22214847 RGD:9587356 NCBI chr 7:111,460,656...111,479,231
Ensembl chr 7:111,460,656...111,477,973 		JBrowse link
G Ccnd1 cyclin D1 treatment
disease_progression		 ISO RGD PMID:19355812 PMID:26681199 RGD:13434927, RGD:11536846 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccnd2 cyclin D2 disease_progression ISO RGD PMID:30308939 RGD:151665105 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495 		JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 2:82,591,750...82,602,903
Ensembl chr 2:82,590,630...82,602,930 		JBrowse link
G Cd44 CD44 molecule (Indian blood group) disease_progression ISO mRNA:splice variants:lung
mRNA:increased expression:lung (human)		 RGD PMID:18091389 PMID:29537891 RGD:2289345, RGD:149735539 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Cdc73 cell division cycle 73 exacerbates ISO mRNA:decreased expression:lung (human) RGD PMID:21692036 RGD:150537041 NCBI chr13:55,357,226...55,449,690
Ensembl chr13:55,357,226...55,449,656 		JBrowse link
G Cdh1 cadherin 1 IDA DNA:increased methylation RGD PMID:16329148 RGD:1599556 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Cdk12 cyclin-dependent kinase 12 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar NCBI chr10:83,201,177...83,256,906
NCBI chr10:83,267,332...83,280,881
Ensembl chr10:83,201,211...83,280,888 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 ISO protein:increased expression:lung
ClinVar Annotator: match by term: Lung adenocarcinoma		 ClinVar
RGD		 PMID:5377176 PMID:7652577 PMID:8528263 PMID:8968104 PMID:9228064 More... RGD:13464277 NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403 		JBrowse link
G Cdk6 cyclin-dependent kinase 6 ISO protein:increased expression:lung RGD PMID:10574260 RGD:13464325 NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A ISO ClinVar Annotator: match by term: Adenocarcinoma of lung ClinVar PMID:7780957 PMID:8521414 PMID:9324288 PMID:10491434 PMID:16234564 More... NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Chd4 chromodomain helicase DNA binding protein 4 ameliorates
susceptibility		 ISO human cells in a mouse model
mRNA:increased expression:lung (human)
DNA:missense mutation:CDS:p.D140E (rs7479004) (human)		 RGD PMID:28486105 PMID:32228507 PMID:29667179 RGD:153323299, RGD:153323307, RGD:151660359 NCBI chr 4:157,898,503...157,931,632
Ensembl chr 4:157,899,391...157,931,541 		JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit susceptibility ISO DNA:SNP: :rs8042374(human)
mRNA,protein:decreased expression:lung
associated with smoking; DNA:SNP: :rs1051730(human)
DNA:SNPs:multiples:multiples (human)
protein:increased expression:lung		 RGD PMID:24686516 PMID:19223495 PMID:20554942 PMID:25233467 PMID:24686516 RGD:151347530, RGD:150524354, RGD:150527848, RGD:151347535, RGD:151347530 NCBI chr 8:55,401,981...55,415,012
Ensembl chr 8:55,401,702...55,415,165 		JBrowse link
G Chrna5 cholinergic receptor nicotinic alpha 5 subunit susceptibility
disease_progression		 ISO associated with smoking; DNA:SNPs: :rs2036527, rs684513, rs667282(human)
DNA:SNP:cds: p.D398N (rs1696996)(human)
DNA:SNP:cds: p.D398N(human)
mRNA:increased expression:lung
DNA:SNP: :rs503464(human)		 RGD PMID:20554942 PMID:19223495 PMID:19577767 PMID:23430818 PMID:20124469 More... RGD:150527848, RGD:150524354, RGD:150524359, RGD:150524356, RGD:150527851, RGD:150527849 NCBI chr 8:55,369,794...55,398,526
Ensembl chr 8:55,369,794...55,398,146 		JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit ISO mRNA:increased expression:lung
DNA:hypomethylation:promoter:		 RGD PMID:20124469 PMID:22945651 RGD:150527851, RGD:151361154 NCBI chr 8:55,418,379...55,436,967
Ensembl chr 8:55,418,313...55,437,027 		JBrowse link
G Clptm1l CLPTM1-like susceptibility
no_association
ameliorates		 ISO mRNA:increased expression:lung
CTD Direct Evidence: marker/mechanism
DNA:SNP: :rs401681(human)
DNA:SNP::rs77518573(human)
DNA:SNP::rs401681(human)
DNA:SNP:: rs4975616(human)
DNA:SNP:: rs31490(human)		 CTD
RGD		 PMID:22675468 PMID:24366883 PMID:24386361 PMID:31935503 PMID:24861918 More... RGD:150530483, RGD:150537098, RGD:150530635, RGD:150530499, RGD:150530502, RGD:150530498, RGD:150530483, RGD:150530485 NCBI chr 1:29,667,545...29,683,530
Ensembl chr 1:29,667,545...29,683,530 		JBrowse link
G Cmtr2 cap methyltransferase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr19:38,190,718...38,197,549
Ensembl chr19:38,190,642...38,197,804 		JBrowse link
G Col10a1 collagen type X alpha 1 chain disease_progression ISO mRNA:increased expression:lung RGD PMID:33324550 PMID:33324550 RGD:150429752, RGD:150429752 NCBI chr20:38,183,103...38,189,488
Ensembl chr20:38,182,494...38,189,494 		JBrowse link
G Crebbp CREB binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888 		JBrowse link
G Csf1r colony stimulating factor 1 receptor ISO protein:increased expression:lung (human) RGD PMID:23702648 RGD:150524280 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415 		JBrowse link
G Csrp3 cysteine and glycine rich protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:98,528,067...98,546,647
Ensembl chr 1:98,528,068...98,546,653 		JBrowse link
G Ctnnb1 catenin beta 1 ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:9065402 PMID:9065403 PMID:9294210 PMID:9500465 PMID:9927029 More... NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 exacerbates ISO mRNA:increased expression:lung (human)
protein:increased expression:lung (human)		 RGD PMID:19716197 PMID:30103827 RGD:152177480, RGD:152023735 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 ISO protein:increased expression:lung (human) RGD PMID:19358281 RGD:152177688 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 ameliorates ISO mRNA:decreased expression:lung (human)
human cell line in a mouse model
DNA:hypomethylation:promoter (human)		 RGD PMID:25519225 PMID:27793774 PMID:24736069 RGD:151665499, RGD:151665173, RGD:151361181 NCBI chr 3:159,275,947...159,290,383
Ensembl chr 3:159,275,947...159,290,383 		JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18669584 NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887 		JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26206333 NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363 		JBrowse link
G Dll4 delta like canonical Notch ligand 4 treatment IEP RGD PMID:33628824 RGD:155663482 NCBI chr 3:106,317,114...106,327,004
Ensembl chr 3:106,316,986...106,326,931 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:21067377 PMID:21518476 PMID:22160010 PMID:22722925 PMID:22744846 More... NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687 		JBrowse link
G Dnmt3b DNA methyltransferase 3 beta susceptibility ISO DNA:SNPs,haplotype:promoter:-283T >C,-579G>T(human) RGD PMID:15528220 RGD:9589086 NCBI chr 3:142,130,592...142,169,124
Ensembl chr 3:142,130,592...142,169,124 		JBrowse link
G Dok1 docking protein 1 disease_progression ISO RGD PMID:20139980 RGD:152177521 NCBI chr 4:115,537,453...115,540,464
Ensembl chr 4:115,537,462...115,540,465 		JBrowse link
G Dok2 docking protein 2 disease_progression
exacerbates		 ISO mRNA:decreased expression:lung (human) RGD PMID:20139980 PMID:30475228 PMID:20139980 PMID:24255704 RGD:152177521, RGD:152177492, RGD:152177521, RGD:152177493 NCBI chr15:45,826,984...45,841,409
Ensembl chr15:45,827,398...45,841,402 		JBrowse link
G Dok3 docking protein 3 disease_progression ISO RGD PMID:20139980 RGD:152177521 NCBI chr17:9,109,633...9,115,188
Ensembl chr17:9,109,597...9,115,188 		JBrowse link
G Dot1l DOT1 like histone lysine methyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr 7:8,917,786...8,959,474
Ensembl chr 7:8,917,786...8,956,475 		JBrowse link
G E2f1 E2F transcription factor 1 ISO mRNA:increased expression:lung RGD PMID:26695082 RGD:13464334 NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361 		JBrowse link
G E2f3 E2F transcription factor 3 ISO RGD PMID:16938365 RGD:13464341 NCBI chr17:34,601,756...34,679,139
Ensembl chr17:34,601,830...34,676,253 		JBrowse link
G Eef2 eukaryotic translation elongation factor 2 exacerbates ISO protein:increased expression:lung (human) RGD PMID:21554491 RGD:153298904 NCBI chr 7:8,533,248...8,538,518
Ensembl chr 7:8,533,116...8,559,183 		JBrowse link
G Eef2k eukaryotic elongation factor-2 kinase ameliorates ISO Human cells in mouse model RGD PMID:30522114 RGD:153298964 NCBI chr 1:175,393,119...175,454,452
Ensembl chr 1:175,393,154...175,455,164 		JBrowse link
G Egf epidermal growth factor ISO DNA:polymorphism: :p.A61G (human) RGD PMID:26625757 RGD:11538684 NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064 		JBrowse link
G Egfr epidermal growth factor receptor disease_progression ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
RGD		 PMID:2302402 PMID:15118073 PMID:15118125 PMID:15329413 PMID:15710947 More... RGD:126790475 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 disease_progression ISO RGD PMID:20940408 RGD:9589170 NCBI chr20:3,919,623...3,936,751
Ensembl chr20:3,919,624...3,941,547 		JBrowse link
G Eif2b1 eukaryotic translation initiation factor 2B subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr12:32,025,593...32,033,848
Ensembl chr12:32,025,557...32,046,601 		JBrowse link
G Eif2b4 eukaryotic translation initiation factor 2B subunit delta ISO CTD Direct Evidence: marker/mechanism CTD PMID:24366584 NCBI chr 6:25,183,177...25,188,832
Ensembl chr 6:25,183,186...25,188,829 		JBrowse link
G Eif2b5 eukaryotic translation initiation factor 2B subunit epsilon ISO CTD Direct Evidence: marker/mechanism CTD PMID:24366584 NCBI chr11:80,394,433...80,404,468
Ensembl chr11:80,394,433...80,404,419 		JBrowse link
G Eif3e eukaryotic translation initiation factor 3 subunit E ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 7:74,339,848...74,372,483
Ensembl chr 7:74,339,828...74,373,096 		JBrowse link
G Eml4 EMAP like 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22980554 PMID:22999080 NCBI chr 6:11,219,545...11,334,824
Ensembl chr 6:11,219,566...11,334,879 		JBrowse link
G Emx2 empty spiracles homeobox 2 exacerbates ISO mRNA,protein:decreased expression:lung (human) RGD PMID:21726823 RGD:153323303 NCBI chr 1:258,626,584...258,633,594
Ensembl chr 1:258,626,584...258,633,594 		JBrowse link
G Eno1 enolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 PMID:27602772 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336 		JBrowse link
G Ep300 E1A binding protein p300 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088 		JBrowse link
G Epha5 EPH receptor A5 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:16140923 NCBI chr14:23,653,393...24,020,135
Ensembl chr14:23,653,393...24,017,317 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 disease_progression ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar
RGD		 PMID:15457249 PMID:22908275 PMID:24033266 PMID:26619011 PMID:26824984 RGD:126790475 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078 		JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 disease_progression ISO RGD PMID:26824984 RGD:126790475 NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525 		JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 disease_progression ISO RGD PMID:26824984 RGD:126790475 NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595 		JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:21327329 NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963 		JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor ISO mRNA, protein:increased expression:lung (human) RGD PMID:31615563 RGD:155260344 NCBI chr16:7,764,983...7,835,587
Ensembl chr16:7,765,013...7,835,587 		JBrowse link
G Ercc6l ERCC excision repair 6 like, spindle assembly checkpoint helicase exacerbates ISO mRNA:increased expression:lung (human) RGD PMID:35150321 RGD:155260359 NCBI chr  X:67,245,414...67,261,222
Ensembl chr  X:67,245,414...67,280,756 		JBrowse link
G Ergic3 ERGIC and golgi 3 ameliorates
disease_progression		 ISO mRNA,protein:increased expression:lung (human) RGD PMID:27588471 PMID:23374247 RGD:153323314, RGD:151708716 NCBI chr 3:144,525,059...144,534,813
Ensembl chr 3:144,525,092...144,534,813 		JBrowse link
G Erp29 endoplasmic reticulum protein 29 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376 		JBrowse link
G Esco2 establishment of sister chromatid cohesion N-acetyltransferase 2 ameliorates ISO RGD PMID:33573689 RGD:155791670 NCBI chr15:40,034,566...40,052,295
Ensembl chr15:40,034,568...40,055,306 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit disease_progression ISO RGD PMID:24097870 RGD:126781716 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362 		JBrowse link
G Fas Fas cell surface death receptor ISO mRNA:decreased expression:lung (human) RGD PMID:29254206 RGD:151665107 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Fasn fatty acid synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G Fbl fibrillarin ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:83,469,832...83,478,932
Ensembl chr 1:83,469,832...83,478,932 		JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 ISO ClinVar Annotator: match by term: Adenocarcinoma of lung ClinVar PMID:26619011 NCBI chr 2:170,150,552...170,310,698
Ensembl chr 2:170,149,694...170,309,941 		JBrowse link
G Fes FES proto-oncogene, tyrosine kinase treatment ISO human cells in a mouse model RGD PMID:31573955 RGD:153323295 NCBI chr 1:134,337,698...134,346,934
Ensembl chr 1:134,337,698...134,346,934 		JBrowse link
G Fgf18 fibroblast growth factor 18 ISO mRNA:decreased expression:lung (human) RGD PMID:19296538 RGD:150429981 NCBI chr10:17,706,011...17,737,702
Ensembl chr10:17,706,174...17,736,818 		JBrowse link
G Fgf9 fibroblast growth factor 9 disease_progression ISO mRNA:decreased expression:lung (human)
protein:increased expression:lung (human)		 RGD PMID:19296538 PMID:19358281 PMID:20464547 RGD:150429981 RGD:152177688, RGD:152975620 NCBI chr15:32,208,993...32,254,952
Ensembl chr15:32,210,074...32,253,309 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:17525745 PMID:18552176 PMID:22238366 PMID:23002168 PMID:23908597 More... NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 ISO ClinVar Annotator: match by term: Adenocarcinoma of lung ClinVar PMID:1908846 PMID:7773297 PMID:8858131 PMID:9677066 PMID:10073901 More... NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341 		JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 disease_progression
exacerbates		 ISO DNA:SNP:exon 9: p.G288R (human)
DNA:SNP:exon 9: p.G388R (rs351855)(human)
human cells in mouse model		 RGD PMID:16061909 PMID:19296538 PMID:29402970 RGD:150429976, RGD:150429981, RGD:150429984 NCBI chr17:9,461,541...9,476,268
Ensembl chr17:9,461,547...9,476,242 		JBrowse link
G Fkbp11 FKBP prolyl isomerase 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 7:129,871,870...129,877,760
Ensembl chr 7:129,871,870...129,875,303 		JBrowse link
G Foxa1 forkhead box A1 ISO mRNA:increased expression:lung
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:34254728 PMID:12234996 PMID:29072684 RGD:151665758, RGD:151665822 NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188 		JBrowse link
G Foxo3 forkhead box O3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19380174 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561 		JBrowse link
G Foxp1 forkhead box P1 IEP mRNA:decreased expression:lung (rat) RGD PMID:16023287 RGD:11561933 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258 		JBrowse link
G Frzb frizzled-related protein severity ISO mRNA:decreased expression:lung (human) RGD PMID:27623992 RGD:32716395 NCBI chr 3:65,332,274...65,365,208
Ensembl chr 3:65,332,277...65,365,208 		JBrowse link
G Fubp1 far upstream element binding protein 1 ISO mRNA:decreased expression:lung (human) RGD PMID:32481602 RGD:151361197 NCBI chr 2:241,159,481...241,186,591
Ensembl chr 2:241,159,512...241,186,602 		JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235 		JBrowse link
G Gar1 GAR1 ribonucleoprotein ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 2:218,375,231...218,382,509
Ensembl chr 2:218,375,353...218,382,524 		JBrowse link
G Gart phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr11:30,864,896...30,891,125
Ensembl chr11:30,865,889...30,891,125 		JBrowse link
G Gjb2 gap junction protein, beta 2 IDA DNA, mRNA:hypermethylation, decreased expression:lung RGD PMID:16637067 RGD:11568669 NCBI chr15:31,260,390...31,278,222
Ensembl chr15:31,260,357...31,278,177 		JBrowse link
G Gnas GNAS complex locus ISO ClinVar Annotator: match by term: Adenocarcinoma of lung ClinVar PMID:1517386 PMID:1594625 PMID:1944469 PMID:2549426 PMID:3720010 More... NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262 		JBrowse link
G Gng11 G protein subunit gamma 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24366584 NCBI chr 4:32,023,003...32,028,443
Ensembl chr 4:32,023,003...32,028,442 		JBrowse link
G Gnpnat1 glucosamine-phosphate N-acetyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr15:18,596,180...18,608,854
Ensembl chr15:18,596,442...18,608,739 		JBrowse link
G Golm1 golgi membrane protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr17:4,995,925...5,044,329
Ensembl chr17:4,996,104...5,034,057 		JBrowse link
G Gpi glucose-6-phosphate isomerase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:86,828,211...86,856,077
Ensembl chr 1:86,828,216...86,856,086 		JBrowse link
G Gpx3 glutathione peroxidase 3 ISO mRNA:decreased expression:lung (human) RGD PMID:23374247 RGD:151708716 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035 		JBrowse link
G Grwd1 glutamate-rich WD repeat containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:96,301,260...96,306,962
Ensembl chr 1:96,301,261...96,307,201 		JBrowse link
G H1f10 H1.10 linker histone ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 4:120,440,515...120,444,705
Ensembl chr 4:120,440,870...120,441,448 		JBrowse link
G Hells helicase, lymphoid specific ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:236,701,704...236,748,239
Ensembl chr 1:236,701,758...236,746,844 		JBrowse link
G Hk1 hexokinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr20:30,230,488...30,332,161
Ensembl chr20:30,230,486...30,332,131 		JBrowse link
G Hk2 hexokinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530 		JBrowse link
G Hmgb2 high mobility group box 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24366584 PMID:27602772 NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140 		JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 7:134,375,318...134,381,610
Ensembl chr 7:134,375,150...134,381,609 		JBrowse link
G Hoxb7 homeo box B7 severity ISO protein:increased expression:lung epithelium (human) RGD PMID:22911672 RGD:10402176 NCBI chr10:81,252,616...81,256,034
Ensembl chr10:81,252,553...81,256,034 		JBrowse link
G Hras HRas proto-oncogene, GTPase ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma		 CTD
ClinVar		 PMID:1904555 PMID:3510078 PMID:11150980 PMID:12835555 PMID:16155195 More... NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615 		JBrowse link
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr  X:21,089,152...21,091,597
Ensembl chr  X:21,089,122...21,109,488 		JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 ISO mRNA:increased expression:lung (human) RGD PMID:23374247 RGD:151708716 NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Htra1 HtrA serine peptidase 1 disease_progression ISO human cells in mouse model RGD PMID:24356998 RGD:152975621 NCBI chr 1:185,497,815...185,547,380
Ensembl chr 1:185,497,735...185,547,379 		JBrowse link
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 disease_progression ISO mRNA:increased expression:lung (human)
ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma
protein:increased expression:blood plasma (human)		 ClinVar
RGD		 PMID:18772396 PMID:19657110 PMID:19798509 PMID:19818334 PMID:20946881 More... RGD:149735539, RGD:149735540 NCBI chr 9:66,534,146...66,563,703
Ensembl chr 9:66,534,146...66,563,708 		JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 severity ISO protein:increased expression:blood serum (human)
protein:increased expression:lung (human)		 RGD PMID:29465809 PMID:30128035 RGD:149735567, RGD:149735564 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025 		JBrowse link
G Igf2r insulin-like growth factor 2 receptor IAGP mRNA:deletions: :c.3698_4902del, c.3366_4902del, c.3817_4697del (rat) RGD PMID:12503077 RGD:1298968 NCBI chr 1:47,979,109...48,067,501
Ensembl chr 1:47,979,109...48,067,501 		JBrowse link
G Ikzf1 IKAROS family zinc finger 1 exacerbates
ameliorates		 ISO protein:increased expression:lung (human)
mRNA:increased expression:lung (human)		 RGD PMID:33738286 PMID:32787735 RGD:151347632, RGD:150540324 NCBI chr14:86,255,065...86,340,839
Ensembl chr14:86,255,065...86,342,416 		JBrowse link
G Il1r2 interleukin 1 receptor type 2 severity
disease_progression		 ISO mRNA:increased expression:lung (human)
mRNA:altered expression:lung (human)		 RGD PMID:29942094 PMID:31921619 RGD:152998998, RGD:152998982 NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725 		JBrowse link
G Impdh2 inosine monophosphate dehydrogenase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 8:109,256,705...109,261,365
Ensembl chr 8:109,256,728...109,261,359 		JBrowse link
G Ipo4 importin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr15:29,117,365...29,127,382
Ensembl chr15:29,117,365...29,127,285 		JBrowse link
G Ipo5 importin 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr15:97,990,755...98,041,074
Ensembl chr15:98,005,299...98,041,126 		JBrowse link
G Iqsec1 IQ motif and Sec7 domain ArfGEF 1 disease_progression ISO RGD PMID:24902879 RGD:153350085 NCBI chr 4:123,168,719...123,488,300
Ensembl chr 4:123,168,719...123,488,172 		JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 ISO mRNA:increased expression:lung (human) RGD PMID:21278795 RGD:36049796 NCBI chr 7:55,653,949...55,714,371
Ensembl chr 7:55,653,962...55,713,121 		JBrowse link
G Jak2 Janus kinase 2 treatment ISO human cells in mouse model RGD PMID:27025877 RGD:11574134 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:24366584 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035 		JBrowse link
G Kcnj4 potassium inwardly-rectifying channel, subfamily J, member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30512237 NCBI chr 7:111,047,097...111,074,151
Ensembl chr 7:111,047,094...111,074,151 		JBrowse link
G Klf5 KLF transcription factor 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr15:76,060,320...76,079,445
Ensembl chr15:76,064,258...76,079,445 		JBrowse link
G Kmt2c lysine methyltransferase 2C disease_progression
onset		 ISO RGD PMID:32867667 PMID:30821106 RGD:151356760, RGD:151356761 NCBI chr 4:9,620,638...9,834,787
Ensembl chr 4:9,609,627...9,833,539 		JBrowse link
G Kpna2 karyopherin subunit alpha 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr10:91,933,951...91,946,115
Ensembl chr10:91,933,951...91,946,150 		JBrowse link
G Kras KRAS proto-oncogene, GTPase ISO DNA:point mutation:CDS:p.G12C (human)
ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
RGD		 PMID:2278970 PMID:3122217 PMID:6320174 PMID:8143615 PMID:8425762 More... RGD:1600465 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Ldha lactate dehydrogenase A ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472 		JBrowse link
G Lect2 leukocyte cell-derived chemotaxin 2 ameliorates ISO human cells in mouse model RGD PMID:30453282 RGD:153323337 NCBI chr17:8,044,759...8,050,983
Ensembl chr17:8,044,759...8,050,983 		JBrowse link
G Lmna lamin A/C ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423 		JBrowse link
G Lmnb1 lamin B1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr18:50,175,861...50,215,210
Ensembl chr18:50,175,874...50,214,502 		JBrowse link
G Lrp1b LDL receptor related protein 1B disease_progression ISO DNA:mutations:multiple: (human) RGD PMID:18948947 RGD:11064706 NCBI chr 3:24,594,302...26,715,037
Ensembl chr 3:24,594,991...26,715,505 		JBrowse link
G Lrrc56 leucine rich repeat containing 56 ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:1904555 PMID:3510078 PMID:11150980 PMID:12835555 PMID:16155195 More... NCBI chr 1:196,299,843...196,315,170
Ensembl chr 1:196,299,846...196,315,172 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma
mRNA:increased expression:lung (human)		 CTD
ClinVar
RGD		 PMID:18632602 PMID:21383288 PMID:22135231 PMID:22197931 PMID:22588879 More... RGD:151665107 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147 		JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 severity ISO RGD PMID:12231543 PMID:21896780 RGD:150429821, RGD:150429783 NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993 		JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 exacerbates ISO human gene in a mouse model RGD PMID:34236045 RGD:155230828 NCBI chr12:2,591,312...2,604,211
Ensembl chr12:2,591,219...2,604,222 		JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 exacerbates ISO RGD PMID:23533274 RGD:151356978 NCBI chr17:53,382,908...53,403,216
Ensembl chr17:53,383,131...53,403,216 		JBrowse link
G Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 ameliorates
exacerbates		 ISO protein:increased expression:lung (human)
human cell line in a mouse model
mRNA, protein:increased expression:lung (human)		 RGD PMID:22824148 PMID:33510968 PMID:28306189 RGD:151347677, RGD:151347681, RGD:151347678 NCBI chr 9:42,200,708...42,326,708
Ensembl chr 9:42,200,278...42,326,698 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 exacerbates ISO mRNA:increased expression:lung (human) RGD PMID:31969449 RGD:151665505 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589 		JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member treatment
severity		 ISO human cells in mouse model
mRNA:increased expression:lung (human)		 RGD PMID:31200834 PMID:31200834 RGD:151356911, RGD:151356911 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303 		JBrowse link
G Meox1 mesenchyme homeobox 1 ISO CTD Direct Evidence: therapeutic CTD PMID:34837450 NCBI chr10:86,818,450...86,837,563
Ensembl chr10:86,818,478...86,837,660 		JBrowse link
G Mir127 microRNA 127 treatment ISO Human cells in mouse model RGD PMID:27869168 RGD:152995353 NCBI chr 6:128,546,215...128,546,311
Ensembl chr 6:128,546,215...128,546,311 		JBrowse link
G Mir154 microRNA 154 ISO associated with nicotine dependence; RNA:decreased expression:blood serum (human) RGD PMID:25386559 RGD:152995475 NCBI chr 6:128,752,947...128,753,030
Ensembl chr 6:128,752,947...128,753,030 		JBrowse link
G Mir20a microRNA 20a ISO RGD PMID:26560875 RGD:11572141 NCBI chr15:92,181,084...92,181,168
Ensembl chr15:92,181,084...92,181,168 		JBrowse link
G Mir21 microRNA 21 disease_progression ISO miRNA:increased expression:sputum (human)
RNA:increased expression:lung (human)		 RGD PMID:27777637 PMID:29892003 RGD:152998954, RGD:152998892 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mir31 microRNA 31 disease_progression
severity		 ISO RNA:increased expression:lung (human) RGD PMID:23946296 PMID:26657862 PMID:29367106 PMID:27215092 RGD:152998944, RGD:11343268, RGD:152998945, RGD:11250998 NCBI chr 5:103,599,038...103,599,143 JBrowse link
G Mki67 marker of proliferation Ki-67 disease_progression ISO protein:altered expression:lung (human) RGD PMID:26942465 RGD:152999419 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762 		JBrowse link
G Mlh1 mutL homolog 1 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:15340264 PMID:17510385 PMID:18307539 PMID:19419416 PMID:22136435 More... NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617 		JBrowse link
G Mre11 MRE11 homolog, double strand break repair nuclease ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 8:11,618,876...11,680,451
Ensembl chr 8:11,632,354...11,678,279 		JBrowse link
G Mrpl12 mitochondrial ribosomal protein L12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr10:105,758,410...105,762,913
Ensembl chr10:105,758,410...105,762,913 		JBrowse link
G Mrps5 mitochondrial ribosomal protein S5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 3:114,821,046...114,837,291
Ensembl chr 3:114,821,046...114,837,291 		JBrowse link
G Ms4a1 membrane spanning 4-domains A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22514692 NCBI chr 1:207,906,370...207,927,028
Ensembl chr 1:207,906,374...207,918,512 		JBrowse link
G Msh2 mutS homolog 2 no_association ISO DNA:polymorphisms:promoter, intron:-118T>C, IVS1+9G>C (human)
DNA:polymorphisms:introns:IVS10+12A>G, IVS12-6T>C (human)		 RGD PMID:16614121 PMID:16614121 RGD:11065547, RGD:11065547 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938 		JBrowse link
G Msh3 mutS homolog 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21327329 NCBI chr 2:23,444,326...23,585,777 JBrowse link
G Msh6 mutS homolog 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21327329 NCBI chr 6:6,562,631...6,579,995
Ensembl chr 6:6,562,632...6,579,956 		JBrowse link
G Muc1 mucin 1, cell surface associated ISO mRNA:increased expression:lung RGD PMID:8694545 RGD:5131260 NCBI chr 2:174,635,559...174,640,738
Ensembl chr 2:174,635,995...174,640,733 		JBrowse link
G Muc4 mucin 4, cell surface associated disease_progression ISO protein:increased expression:trachea RGD PMID:17126950 RGD:5131208 NCBI chr11:68,008,245...68,053,229 JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor ISO human cell line in mouse model
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Lung adenocarcinoma		 CTD
ClinVar
RGD		 PMID:25157968 PMID:26619011 PMID:26656844 PMID:27602772 PMID:20033209 RGD:7207787 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor ameliorates
treatment		 ISO mouse cell line in a mouse model RGD PMID:30712876 PMID:32140881 RGD:150540309, RGD:150520172 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Naa10 N(alpha)-acetyltransferase 10, NatA catalytic subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr  X:151,656,056...151,661,304
Ensembl chr  X:151,656,056...151,661,252 		JBrowse link
G Naip6 NLR family, apoptosis inhibitory protein 6 ameliorates ISO mRNA:increased expression:lung (human) RGD PMID:31964418 RGD:153344516 NCBI chr 2:31,507,423...31,559,098
Ensembl chr 2:31,507,424...31,570,542 		JBrowse link
G Ncapg non-SMC condensin I complex, subunit G ISO CTD Direct Evidence: marker/mechanism CTD PMID:34419073 NCBI chr14:65,404,235...65,432,902
Ensembl chr14:65,404,163...65,432,902 		JBrowse link
G Ncl nucleolin ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 9:86,999,588...87,008,112
Ensembl chr 9:86,998,019...87,008,136 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:26619011 PMID:29018201 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nop56 NOP56 ribonucleoprotein ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 3:117,476,963...117,481,847
Ensembl chr 3:117,477,053...117,481,841 		JBrowse link
G Nop58 NOP58 ribonucleoprotein ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 9:61,120,939...61,144,810
Ensembl chr 9:61,120,929...61,144,810 		JBrowse link
G Notch1 notch receptor 1 treatment IEP RGD PMID:33628824 RGD:155663482 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Npm1 nucleophosmin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645 		JBrowse link
G Npm3 nucleophosmin/nucleoplasmin, 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:244,595,638...244,597,623
Ensembl chr 1:244,595,644...244,597,591 		JBrowse link
G Nras NRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Adenocarcinoma of lung ClinVar PMID:1654209 PMID:2278970 PMID:2674680 PMID:3122217 PMID:6587382 More... NCBI chr 2:190,582,885...190,593,509
Ensembl chr 2:190,582,918...190,591,626 		JBrowse link
G Nudt21 nudix hydrolase 21 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr19:10,974,800...10,993,841
Ensembl chr19:10,974,241...10,991,682 		JBrowse link
G Nuf2 NUF2 component of NDC80 kinetochore complex disease_progression ISO RGD PMID:32226507 RGD:28912743 NCBI chr13:81,693,675...81,722,765
Ensembl chr13:81,693,598...81,722,766 		JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23951099 NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766 		JBrowse link
G Pabpc4 poly(A) binding protein, cytoplasmic 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 5:135,563,142...135,578,985
Ensembl chr 5:135,563,562...135,578,979 		JBrowse link
G Pacrg parkin coregulated ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:12719539 NCBI chr 1:49,882,671...50,305,564
Ensembl chr 1:49,882,630...50,305,430 		JBrowse link
G Pcbd1 pterin-4 alpha-carbinolamine dehydratase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr20:29,037,545...29,044,322
Ensembl chr20:28,953,864...29,044,292
Ensembl chr20:28,953,864...29,044,292 		JBrowse link
G Pign phosphatidylinositol glycan anchor biosynthesis, class N ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr13:21,659,092...21,812,932
Ensembl chr13:21,662,455...21,806,790 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma		 CTD
ClinVar		 PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 More... NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 ISO mRNA:decreased expression:lung RGD PMID:26695082 RGD:13464334 NCBI chr 2:32,878,942...32,963,611
Ensembl chr 2:32,882,032...32,963,631 		JBrowse link
G Plcg1 phospholipase C, gamma 1 exacerbates ISO protein:decreased expression:lung (human) RGD PMID:33077911 RGD:151356960 NCBI chr 3:149,385,587...149,416,330
Ensembl chr 3:149,385,587...149,416,330 		JBrowse link
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 disease_progression ISO RGD PMID:29072684 RGD:151665822 NCBI chr 8:93,084,548...93,167,255
Ensembl chr 8:93,084,513...93,167,255 		JBrowse link
G Pold1 DNA polymerase delta 1, catalytic subunit exacerbates ISO protein:increased expression:lung (human) RGD PMID:33442399 RGD:153323317 NCBI chr 1:95,025,462...95,041,559
Ensembl chr 1:95,025,499...95,036,465 		JBrowse link
G Polr1d RNA polymerase I and III subunit D ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr12:7,970,592...8,004,157
Ensembl chr12:7,970,595...8,005,624 		JBrowse link
G Ppan peter pan homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 8:19,423,908...19,427,941
Ensembl chr 8:19,423,961...19,427,938 		JBrowse link
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha ISO ClinVar Annotator: match by term: Adenocarcinoma of lung ClinVar PMID:25741868 PMID:26168268 PMID:26619011 PMID:28492532 PMID:31687265 NCBI chr 1:60,540,223...60,559,467
Ensembl chr 1:60,540,194...60,560,129 		JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974 		JBrowse link
G Prame PRAME nuclear receptor transcriptional regulator ISO mRNA:decreased expression:lung (human) RGD PMID:27241212 RGD:11535020 NCBI chr  X:98,567,994...98,574,654
Ensembl chr  X:98,569,415...98,572,096 		JBrowse link
G Prdm1 PR/SET domain 1 exacerbates ISO RGD PMID:28378641 RGD:150530469 NCBI chr20:47,959,858...47,981,488
Ensembl chr20:47,959,858...47,981,488 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:12719539 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Psat1 phosphoserine aminotransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:213,196,709...213,218,564
Ensembl chr 1:213,196,709...213,218,682 		JBrowse link
G Ptch1 patched 1 ISO RGD PMID:33359005 RGD:150524339 NCBI chr17:1,542,705...1,607,730
Ensembl chr17:1,542,877...1,607,333 		JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 ISO ClinVar Annotator: match by term: Adenocarcinoma of lung ClinVar PMID:26619011 PMID:26822237 NCBI chr12:35,365,436...35,424,925
Ensembl chr12:35,383,144...35,424,925 		JBrowse link
G Ptpn13 protein tyrosine phosphatase, non-receptor type 13 exacerbates
susceptibility		 ISO DNA:missense mutations:cds:p.I1522M, p.Y2081D (human)
mRNA,protein:decreased expression:lung		 RGD PMID:33536603 PMID:19672627 PMID:22245727 RGD:152975626, RGD:152176665, RGD:152176663 NCBI chr14:6,108,202...6,282,619
Ensembl chr14:6,108,211...6,282,563 		JBrowse link
G Ptprb protein tyrosine phosphatase, receptor type, B disease_progression ISO mRNA:altered expression:lung (human)
mRNA:decreased expression:lung (human)		 RGD PMID:29254206 PMID:7981622 RGD:151665107, RGD:151665112 NCBI chr 7:51,953,375...52,034,751
Ensembl chr 7:51,930,015...52,034,748 		JBrowse link
G Ptprj protein tyrosine phosphatase, receptor type, J susceptibility ISO DNA:missense mutations:cds:p.R326Q, p.Q276P (human) RGD PMID:19672627 RGD:152176665 NCBI chr 3:76,405,917...76,561,842
Ensembl chr 3:76,405,927...76,562,260 		JBrowse link
G Rac1 Rac family small GTPase 1 exacerbates
ameliorates		 ISO mRNA:increased expression:lung (human) RGD PMID:31779616 PMID:32366477 RGD:152998910, RGD:153345550 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251 		JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase ISO ClinVar Annotator: match by term: Adenocarcinoma of lung ClinVar PMID:1760348 PMID:8601312 PMID:10064593 PMID:12077328 PMID:17603482 More... NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317 		JBrowse link
G Rangrf RAN guanine nucleotide release factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr10:53,677,467...53,678,880
Ensembl chr10:53,677,467...53,678,840 		JBrowse link
G Rarb retinoic acid receptor, beta ISO DNA:hypomethylation:lung RGD PMID:26695082 RGD:13464334 NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288 		JBrowse link
G Rasa1 RAS p21 protein activator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr 2:15,857,704...15,940,757
Ensembl chr 2:15,857,980...15,940,854 		JBrowse link
G Rbm10 RNA binding motif protein 10 ISO mRNA, protein:decreased expression:lung
DNA:missense mutations, protein-truncating variants: :multiple		 RGD PMID:29085465 PMID:22980975 PMID:30955253 RGD:151356983, RGD:11097386, RGD:151356984 NCBI chr  X:1,540,399...1,572,571
Ensembl chr  X:1,540,398...1,572,575 		JBrowse link
G Rcl1 RNA terminal phosphate cyclase-like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:226,824,524...226,869,046
Ensembl chr 1:226,824,534...226,902,315 		JBrowse link
G Rfc4 replication factor C subunit 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr11:77,749,642...77,764,123
Ensembl chr11:77,749,638...77,764,122 		JBrowse link
G Rhoa ras homolog family member A ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:26619011 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746 		JBrowse link
G Rnaseh2a ribonuclease H2, subunit A ISO CTD Direct Evidence: marker/mechanism CTD PMID:34254728 NCBI chr19:23,186,325...23,196,045
Ensembl chr19:23,186,383...23,196,041 		JBrowse link
G Rnf43 ring finger protein 43 severity ISO human cells in a mouse model RGD PMID:31286874 RGD:151361222 NCBI chr10:72,461,508...72,535,977
Ensembl chr10:72,464,348...72,536,977 		JBrowse link
G Ros1 ROS proto-oncogene 1 , receptor tyrosine kinase ISO ClinVar Annotator: match by term: Lung adenocarcinoma
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD		 PMID:22215748 PMID:23724914 NCBI chr20:31,432,636...31,583,998
Ensembl chr20:31,432,637...31,583,865 		JBrowse link
G Rpl10a ribosomal protein L10A ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr20:6,388,800...6,391,358
Ensembl chr20:6,385,823...6,391,357 		JBrowse link
G Rpl13a ribosomal protein L13A ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:95,609,374...95,612,557
Ensembl chr 1:95,609,370...95,620,463 		JBrowse link
G Rpl27a ribosomal protein L27A ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:163,539,732...163,542,771 JBrowse link
G Rpl36a ribosomal protein L36A ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr  X:97,766,179...97,768,892
Ensembl chr  X:97,766,179...97,768,892 		JBrowse link
G Rpsa ribosomal protein SA ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 8:119,851,225...119,855,103
Ensembl chr 8:119,851,225...119,855,247 		JBrowse link
G Rrm1 ribonucleotide reductase catalytic subunit M1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:156,823,960...156,848,262
Ensembl chr 1:156,823,960...156,848,261 		JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773 		JBrowse link
G Rrs1 ribosome biogenesis regulator 1 homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 5:9,733,486...9,735,119
Ensembl chr 5:9,733,091...9,735,140 		JBrowse link
G Runx1 RUNX family transcription factor 1 ISO RGD PMID:28926105 RGD:126779571 NCBI chr11:31,839,880...32,074,427
Ensembl chr11:31,843,764...32,074,542 		JBrowse link
G Satb1 SATB homeobox 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 9:4,677,817...4,773,061
Ensembl chr 9:4,680,920...4,753,251 		JBrowse link
G Sdc1 syndecan 1 ISO mRNA:increased expression:lung (human) RGD PMID:23374247 RGD:151708716 NCBI chr 6:31,562,799...31,585,267
Ensembl chr 6:31,562,739...31,585,264 		JBrowse link
G Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N ISO protein:increased expression:cytoplasm RGD PMID:8620411 RGD:5147446 NCBI chr 6:123,323,632...123,331,166
Ensembl chr 6:123,323,629...123,332,433 		JBrowse link
G Setd2 SET domain containing 2, histone lysine methyltransferase ameliorates
severity
exacerbates		 ISO human cells and genes in mouse model
DNA:mutations:multiple (human)		 RGD PMID:33223508 PMID:33707235 PMID:28202515 PMID:27687306 RGD:150429633, RGD:150429648, RGD:126848875, RGD:150429649 NCBI chr 8:110,511,808...110,597,489
Ensembl chr 8:110,511,772...110,597,489 		JBrowse link
G Sfn stratifin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 Ensembl chr 5:145,826,201...145,831,314 JBrowse link
G Sftpc surfactant protein C ISO CTD Direct Evidence: marker/mechanism CTD PMID:25851810 NCBI chr15:45,596,565...45,599,615
Ensembl chr15:45,596,574...45,610,777 		JBrowse link
G Sfxn1 sideroflexin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr17:10,486,250...10,522,640
Ensembl chr17:10,486,271...10,522,529 		JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr10:45,468,698...45,497,820
Ensembl chr10:45,468,700...45,497,820 		JBrowse link
G Slc15a2 solute carrier family 15 member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr11:64,014,182...64,043,228
Ensembl chr11:64,014,182...64,043,225 		JBrowse link
G Slc19a1 solute carrier family 19 member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr20:11,584,410...11,602,429
Ensembl chr20:11,584,411...11,601,972 		JBrowse link
G Slc1a5 solute carrier family 1 member 5 disease_progression ISO RGD PMID:26279756 RGD:151361150 NCBI chr 1:77,456,849...77,470,952
Ensembl chr 1:77,456,694...77,470,952 		JBrowse link
G Slc22a18 solute carrier family 22, member 18 disease_progression ISO mRNA:increased expression:lung (human) RGD PMID:32726996 RGD:150557423 NCBI chr 1:198,670,626...198,694,977
Ensembl chr 1:198,671,731...198,694,975 		JBrowse link
G Slc3a2 solute carrier family 3 member 2 disease_progression ISO RGD PMID:19171406 RGD:151361151 NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931 		JBrowse link
G Slc4a4 solute carrier family 4 member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr14:18,841,289...19,293,297
Ensembl chr14:18,845,159...19,272,883 		JBrowse link
G Slc4a7 solute carrier family 4 member 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr15:10,585,307...10,664,781
Ensembl chr15:10,588,979...10,664,781 		JBrowse link
G Slc7a5 solute carrier family 7 member 5 disease_progression ISO RGD PMID:19171406 PMID:26279756 RGD:151361151, RGD:151361150 NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823 		JBrowse link
G Smad4 SMAD family member 4 ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:6604412 PMID:8898652 PMID:9214508 PMID:9285566 PMID:9582123 More... NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438 		JBrowse link
G Smarcc1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 8:110,111,097...110,214,727
Ensembl chr 8:110,111,122...110,214,720 		JBrowse link
G Snord22 small nucleolar RNA, C/D box 22 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr11:9,097,799...9,097,923
Ensembl chr11:9,097,799...9,097,923 		JBrowse link
G Snrpb small nuclear ribonucleoprotein polypeptides B and B1 severity ISO mRNA:increased expression:lung (human) RGD PMID:22876301 RGD:10768834 NCBI chr 3:117,369,816...117,379,344
Ensembl chr 3:117,370,100...117,379,339 		JBrowse link
G Snrpe small nuclear ribonucleoprotein polypeptide E severity ISO mRNA:increased expression:lung (human) RGD PMID:22876301 RGD:10768834 NCBI chr13:45,050,986...45,057,231
Ensembl chr13:45,050,986...45,057,310 		JBrowse link
G Snrpg small nuclear ribonucleoprotein polypeptide G ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 4:118,812,278...118,819,827
Ensembl chr 4:118,812,252...118,819,826 		JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 ISO ClinVar Annotator: match by term: Lung adenocarcinoma
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD		 PMID:26619011 PMID:27158780 NCBI chr 6:14,533,870...14,613,348
Ensembl chr 6:14,533,360...14,611,107 		JBrowse link
G Sox2 SRY-box transcription factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25184679 NCBI chr 2:117,536,929...117,539,338
Ensembl chr 2:117,536,929...117,539,338 		JBrowse link
G Sox30 SRY-box transcription factor 30 disease_progression ISO RGD PMID:26330328 RGD:11535423 NCBI chr10:30,417,499...30,446,441
Ensembl chr10:30,418,473...30,446,453 		JBrowse link
G Sox4 SRY-box transcription factor 4 ISO protein:increased expression:lung RGD PMID:29882245 RGD:153297792 NCBI chr17:35,667,809...35,672,515
Ensembl chr17:35,667,537...35,673,665 		JBrowse link
G Spop speckle type BTB/POZ protein ameliorates ISO human gene and cell line in mouse model
mRNA, protein:increased expression:lung (human)		 RGD PMID:30607139 PMID:31105033 RGD:153298920, RGD:153298927 NCBI chr10:80,358,121...80,438,983
Ensembl chr10:80,358,124...80,483,955 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase severity ISO RGD PMID:12826049 RGD:150521546 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Srm spermidine synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 5:159,025,919...159,029,076
Ensembl chr 5:159,025,873...159,029,405 		JBrowse link
G Srr serine racemase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr10:59,769,563...59,786,688
Ensembl chr10:59,769,571...59,787,011 		JBrowse link
G Srsf1 serine and arginine rich splicing factor 1 severity ISO RGD PMID:23071587 RGD:150429662 NCBI chr10:72,838,926...72,859,066
Ensembl chr10:72,839,274...72,845,336 		JBrowse link
G Srsf2 serine and arginine rich splicing factor 2 severity ISO RGD PMID:23071587 RGD:150429662 NCBI chr10:102,052,158...102,055,365
Ensembl chr10:102,052,314...102,055,338 		JBrowse link
G Stk11 serine/threonine kinase 11 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Lung adenocarcinoma		 CTD
ClinVar		 PMID:10408777 PMID:12865922 PMID:15863673 PMID:16287113 PMID:16582077 More... NCBI chr 7:9,574,553...9,591,315
Ensembl chr 7:9,575,269...9,591,315 		JBrowse link
G Stk39 serine threonine kinase 39 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 3:52,913,583...53,179,060
Ensembl chr 3:52,913,585...53,179,060 		JBrowse link
G Strbp spermatid perinuclear RNA binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 3:21,328,310...21,467,753
Ensembl chr 3:21,337,855...21,414,949 		JBrowse link
G Suclg2 succinate-CoA ligase GDP-forming subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 4:128,067,031...128,337,146
Ensembl chr 4:128,067,033...128,337,170 		JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 ISO DNA:SNP:exon:p.R213H, 638G>A (human) RGD PMID:14688021 RGD:1581441 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562 		JBrowse link
G Tert telomerase reverse transcriptase susceptibility ISO DNA:SNP: :rs2736098(human)
DNA:SNP::rs33963617(human)
DNA:SNPs:: rs2853669,rs2736108(human)
DNA:SNP:: rs2736100(human)		 RGD PMID:23738012 PMID:31935503 PMID:23908149 PMID:19955392 PMID:24761905 RGD:150530485, RGD:150530635, RGD:150530498, RGD:150530502, RGD:150530628 NCBI chr 1:29,637,213...29,659,509
Ensembl chr 1:29,637,506...29,659,561 		JBrowse link
G Tf transferrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511 		JBrowse link
G Timm10 translocase of inner mitochondrial membrane 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 3:69,908,397...69,911,943
Ensembl chr 3:69,908,456...69,911,940 		JBrowse link
G Timm8a1 translocase of inner mitochondrial membrane 8A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr  X:97,717,932...97,721,918
Ensembl chr  X:97,717,920...97,721,960 		JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 ISO mRNA:decreased expression:lung (human) RGD PMID:23374247 RGD:151708716 NCBI chr 7:17,520,827...17,571,871
Ensembl chr 7:17,521,919...17,571,839 		JBrowse link
G Tk1 thymidine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr10:103,034,755...103,046,125
Ensembl chr10:103,031,521...103,046,920 		JBrowse link
G Tnfsf10 TNF superfamily member 10 ISO CTD Direct Evidence: therapeutic CTD PMID:24345465 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135 		JBrowse link
G Tomm40 translocase of outer mitochondrial membrane 40 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:79,358,781...79,370,976
Ensembl chr 1:79,358,786...79,370,915 		JBrowse link
G Top2a DNA topoisomerase II alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr10:83,946,186...83,975,694
Ensembl chr10:83,945,735...83,976,874 		JBrowse link
G Tp53 tumor protein p53 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma		 CTD
ClinVar		 PMID:1349175 PMID:1359493 PMID:1565143 PMID:1565144 PMID:1569604 More... NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tp63 tumor protein p63 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24880342 NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398 		JBrowse link
G Tpi1 triosephosphate isomerase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541 		JBrowse link
G Traf4 Tnf receptor associated factor 4 ISO mRNA:increased expression:lung (human) RGD PMID:29254206 RGD:151665107 NCBI chr10:63,054,169...63,060,284
Ensembl chr10:63,054,181...63,060,284 		JBrowse link
G Ttf1 transcription termination factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25851810 NCBI chr 3:12,384,626...12,409,257
Ensembl chr 3:12,384,655...12,409,257 		JBrowse link
G Ttr transthyretin ISO mRNA,protein:increased expression:lung (human) RGD PMID:26943652 RGD:151665207 NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008 		JBrowse link
G Tyms thymidylate synthetase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536 		JBrowse link
G U2af1 U2 small nuclear RNA auxiliary factor 1 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:22158538 PMID:23029227 PMID:23861105 PMID:24498085 PMID:26619011 NCBI chr20:9,742,904...9,753,840
Ensembl chr20:9,742,905...9,753,832 		JBrowse link
G Ubr5 ubiquitin protein ligase E3 component n-recognin 5 ameliorates ISO human cell line in a mouse model RGD PMID:32867711 RGD:151665200 NCBI chr 7:69,116,758...69,224,490
Ensembl chr 7:69,116,761...69,224,903 		JBrowse link
G Uck2 uridine-cytidine kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr13:79,380,807...79,438,352
Ensembl chr13:79,383,846...79,438,352 		JBrowse link
G Vav1 vav guanine nucleotide exchange factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr 9:2,161,985...2,209,951
Ensembl chr 9:2,157,900...2,208,937 		JBrowse link
G Wrap53 WD repeat containing, antisense to TP53 severity ISO RGD PMID:28347242 RGD:21081522 NCBI chr10:54,282,092...54,299,908
Ensembl chr10:54,282,105...54,298,929 		JBrowse link
G Xpc XPC complex subunit, DNA damage recognition and repair factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:21327329 PMID:27777383 NCBI chr 4:123,993,670...124,020,922
Ensembl chr 4:123,993,666...124,021,010 		JBrowse link
G Xpo1 exportin 1 exacerbates ISO circRNA:increased expression:lung (human) RGD PMID:33268793 RGD:151665799 NCBI chr14:97,233,263...97,275,536
Ensembl chr14:97,233,270...97,275,498 		JBrowse link
G Xrcc1 X-ray repair cross complementing 1 susceptibility
severity		 ISO DNA:missense mutation:cds: p.R399Q (human)
DNA:missense mutation:exon 10: p.R399Q (rs25487) (human)		 RGD PMID:11104903 PMID:20003463 RGD:151347406, RGD:151347422 NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701 		JBrowse link
G Xrcc5 X-ray repair cross complementing 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 9:73,955,220...74,044,020
Ensembl chr 9:73,955,216...74,044,018 		JBrowse link
G Xrcc6 X-ray repair cross complementing 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 7:113,542,992...113,563,762
Ensembl chr 7:113,543,057...113,563,762 		JBrowse link
G Zfhx3 zinc finger homeobox 3 ameliorates ISO DNA:mutations:multiple (human) RGD PMID:32653938 RGD:151361163 NCBI chr19:36,257,196...36,886,104
Ensembl chr19:36,630,254...36,881,771 		JBrowse link
lung adenoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anapc2 anaphase promoting complex subunit 2 ISO mRNA:decreased expression:lung (human) RGD PMID:14647414 RGD:10047051 NCBI chr 3:8,086,434...8,098,182
Ensembl chr 3:8,086,462...8,098,178 		JBrowse link
G Mir21 microRNA 21 ISO RNA:increased expression:lung: RGD PMID:20956945 RGD:41404697 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
lung cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 treatment ISO RGD PMID:35289739 RGD:153344587 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114 		JBrowse link
G Ace angiotensin I converting enzyme susceptibility ISO DNA:polymorphism (human) RGD PMID:20303010 RGD:4140486 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131 		JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 ISO RGD PMID:23936004 RGD:13831302 NCBI chr 9:80,140,996...80,164,636
Ensembl chr 9:80,115,112...80,164,627 		JBrowse link
G Alk ALK receptor tyrosine kinase ISO ClinVar Annotator: match by term: Lung cancer ClinVar PMID:20979473 PMID:21575866 PMID:22277784 PMID:24327273 PMID:24670165 More... NCBI chr 6:22,879,653...23,599,636
Ensembl chr 6:22,880,625...23,598,034 		JBrowse link
G Alx4 ALX homeobox 4 ISO DNA:hypermethylation:CpG_island: RGD PMID:24037716 RGD:153344522 NCBI chr 3:79,611,682...79,648,260
Ensembl chr 3:79,611,719...79,648,260 		JBrowse link
G Arid1a AT-rich interaction domain 1A ISO ClinVar Annotator: match by term: Lung cancer, somatic ClinVar NCBI chr 5:145,908,181...145,981,609
Ensembl chr 5:145,908,181...145,985,564 		JBrowse link
G Arid2 AT-rich interaction domain 2 ISO ClinVar Annotator: match by term: Lung cancer ClinVar NCBI chr 7:127,447,192...127,565,987
Ensembl chr 7:127,447,278...127,563,512 		JBrowse link
G Atm ATM serine/threonine kinase ISO ClinVar Annotator: match by term: Lung cancer ClinVar PMID:21665257 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Atr ATR serine/threonine kinase treatment ISO RGD PMID:25010037 RGD:150340694 NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136 		JBrowse link
G Axin1 axin 1 treatment
disease_progression		 ISO human cells in mouse model
DNA:hypermethylation
protein:decreased expression:lung (human)		 RGD PMID:23915259 PMID:23192643 PMID:21496867 PMID:32051824 RGD:150530274, RGD:150527862, RGD:150530293, RGD:150530284 NCBI chr10:15,163,684...15,215,615
Ensembl chr10:15,163,684...15,215,615 		JBrowse link
G Axin2 axin 2 susceptibility ISO DNA:SNPs:exons,introns:
DNA:SNP:exon:148T>C(rs2240308)(human)		 RGD PMID:28378643 PMID:25091576 RGD:151356504, RGD:151356659 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231 		JBrowse link
G Bard1 BRCA1 associated RING domain 1 ISO ClinVar Annotator: match by term: Lung cancer ClinVar PMID:20077502 PMID:25741868 PMID:26467025 PMID:26738429 PMID:28492532 NCBI chr 9:72,616,070...72,694,553
Ensembl chr 9:72,623,155...72,694,265 		JBrowse link
G Bmp2 bone morphogenetic protein 2 ISO ClinVar Annotator: match by term: Lung cancer ClinVar PMID:21515830 PMID:24465802 PMID:26253951 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase ISO ClinVar Annotator: match by term: Lung cancer | ClinVar Annotator: match by term: Lung cancer, somatic ClinVar PMID:18039235 PMID:18413255 PMID:20395089 PMID:21871821 PMID:24033266 More... NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463 		JBrowse link
G Brca1 BRCA1, DNA repair associated ISO ClinVar Annotator: match by term: Lung cancer, somatic ClinVar PMID:8554067 PMID:9760198 PMID:10486320 PMID:11739404 PMID:11802209 More... NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304 		JBrowse link
G Calr calreticulin treatment ISO protein:increased expression:blood serum (human)
human cells and recombinant gene in a mouse model		 RGD PMID:26314964 PMID:32161598 PMID:22083347 PMID:24111870 PMID:12215887 RGD:150520159, RGD:150521699, RGD:150521704, RGD:150521678, RGD:150521700 NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414 		JBrowse link
G Car12 carbonic anhydrase 12 ISO protein:increased expression:serum; RGD PMID:22439015 RGD:155226862 NCBI chr 8:67,274,739...67,330,428
Ensembl chr 8:67,274,359...67,330,440 		JBrowse link
G Casp8 caspase 8 ISO ClinVar Annotator: match by term: Lung cancer, protection against ClinVar PMID:17450141 PMID:18305469 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Ccdc116 coiled-coil domain containing 116 ISO DNA:SNP:promoter:rs3747093 (human) RGD PMID:29193083 RGD:153297750 NCBI chr11:83,842,707...83,850,607
Ensembl chr11:83,845,557...83,850,607 		JBrowse link
G Ccl22 C-C motif chemokine ligand 22 disease_progression ISO RGD PMID:16453150 RGD:4891472 NCBI chr19:10,257,602...10,264,373
Ensembl chr19:10,257,601...10,264,400 		JBrowse link
G Ccng1 cyclin G1 treatment ISO human cells in mouse model RGD PMID:25472877 RGD:151361106 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641 		JBrowse link
G Cd164 CD164 molecule exacerbates ISO protein:increased expression:lung (human) RGD PMID:28903328 RGD:11555304 NCBI chr20:45,024,051...45,035,628
Ensembl chr20:45,023,973...45,035,634 		JBrowse link
G Cdc27 cell division cycle 27 ISO ClinVar Annotator: match by term: Lung cancer ClinVar NCBI chr10:89,400,931...89,449,823
Ensembl chr10:89,400,940...89,449,736 		JBrowse link
G Cdc73 cell division cycle 73 exacerbates ISO mRNA:increased expression:lung (human) RGD PMID:29221126 RGD:150539444 NCBI chr13:55,357,226...55,449,690
Ensembl chr13:55,357,226...55,449,656 		JBrowse link
G Cdh10 cadherin 10 ISO ClinVar Annotator: match by term: Lung cancer ClinVar NCBI chr 2:68,628,623...68,850,995
Ensembl chr 2:68,628,780...68,850,995 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B disease_progression IEP protein:decreased expression:lung (rat) RGD PMID:20512841 RGD:152998913 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C disease_progression IAGP
IEP		 DNA:hypermethylation:promoter (rat)
protein:decreased expression:lung (rat)		 RGD PMID:20512841 PMID:20512841 RGD:152998913, RGD:152998913 NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A ISO ClinVar Annotator: match by term: Lung cancer ClinVar PMID:7777061 PMID:9751050 PMID:10498896 PMID:10892805 PMID:18803811 More... NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Cftr CF transmembrane conductance regulator susceptibility ISO DNA:deletion, SNP, haplotype: :p.F508del, rs10487372 (human) RGD PMID:20116881 RGD:11566029 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756 		JBrowse link
G Chd4 chromodomain helicase DNA binding protein 4 ameliorates ISO DNA:missense mutation:CDS p.D140E (rs7479004) (human)
mRNA:increased expression:lung (human)		 RGD PMID:30031117 PMID:25407497 RGD:153323309, RGD:153323305 NCBI chr 4:157,898,503...157,931,632
Ensembl chr 4:157,899,391...157,931,541 		JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit susceptibility
onset		 ISO ClinVar Annotator: match by term: Lung cancer susceptibility 2
associated with smoking; DNA:SNP::rs1051730(human)
DNA:SNP:exon 2: rs8040868(T>C) (human)
DNA:SNP:cds:rs3743073(human)
DNA:SNP: :rs6495309(human)
DNA:haplotype:promoter:rs6495309(human)
associated with smoking; DNA:SNP: :rs1051730(human)		 OMIM
ClinVar
RGD		 PMID:18385676 PMID:18385738 PMID:18385739 PMID:28492532 PMID:29993116 More... RGD:150526806, RGD:151361155, RGD:151347454, RGD:151347536, RGD:151347534, RGD:151347455 NCBI chr 8:55,401,981...55,415,012
Ensembl chr 8:55,401,702...55,415,165 		JBrowse link
G Chrna5 cholinergic receptor nicotinic alpha 5 subunit susceptibility ISO DNA:haplotype:promoter
DNA:SNP:intron:rs17486278(human)
DNA:SNP::rs16969968 (human)
ClinVar Annotator: match by term: Lung cancer susceptibility 2
associated with smoking; DNA:SNP::rs16969968 (human)
DNA:SNP:exon, intron:rs1051730, rs1847529 (human)		 OMIM
ClinVar
RGD		 PMID:18385738 PMID:18385739 PMID:18618000 PMID:19132693 PMID:19443489 More... RGD:150524361, RGD:150527839, RGD:150524357, RGD:150526806, RGD:153297750 NCBI chr 8:55,369,794...55,398,526
Ensembl chr 8:55,369,794...55,398,146 		JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit disease_progression ISO DNA:CNV:: CNV-3956(human) RGD PMID:25407004 RGD:11074492 NCBI chr 1:116,715,286...116,837,223
Ensembl chr 1:116,714,711...116,837,240 		JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit susceptibility ISO DNA:SNP:3'utr: (rs1948)C>T (human)
DNA:SNP: :rs7178270(human)		 RGD PMID:29416783 PMID:20587604 RGD:151361155, RGD:150527839 NCBI chr 8:55,418,379...55,436,967
Ensembl chr 8:55,418,313...55,437,027 		JBrowse link
G Clptm1l CLPTM1-like susceptibility
disease_progression
sexual_dimorphism 		ISO DNA:SNPs::multiple (human)
in males;DNA:SNP: :rs370348(human)
DNA:SNPs:: rs402710,rs451360 (human)
DNA:SNP:intron:rs31489(human)
associated with smoking; DNA:SNP:intron:rs31489(human) 		RGD PMID:27062701 PMID:26852039 PMID:21771723 PMID:25526467 PMID:25422207 More... RGD:150537097, RGD:150530484, RGD:150530643, RGD:150530494, RGD:150530631, RGD:150530642, RGD:150530483 NCBI chr 1:29,667,545...29,683,530
Ensembl chr 1:29,667,545...29,683,530 		JBrowse link
G Csf1r colony stimulating factor 1 receptor exacerbates
susceptibility		 ISO protein:increased expression:lung (human)
DNA:missense mutation:CDS:p.H362R (rs10079250) (human)		 RGD PMID:29323162 PMID:25144241 RGD:150524284, RGD:150524283 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415 		JBrowse link
G Ctnnb1 catenin beta 1 treatment ISO human cells in mouse model
ClinVar Annotator: match by term: Lung cancer, somatic		 ClinVar
RGD		 PMID:9065403 PMID:10027390 PMID:10192393 PMID:11351304 PMID:11930117 More... RGD:150530284 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Ctnnd2 catenin delta 2 ISO ClinVar Annotator: match by term: Lung cancer ClinVar NCBI chr 2:81,168,976...82,016,495
Ensembl chr 2:81,167,117...82,015,764 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 ISO associated with Pulmonary Emphysema;DNA:polymorphism: :p.I462V (human) RGD PMID:16696009 RGD:4892075 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 sexual_dimorphism ISO DNA:SNP:intron: (rs2765934) (human)
mRNA:increased expression:lung (human)		 RGD PMID:31264381 PMID:16180015 RGD:151665340, RGD:151361183 NCBI chr 3:159,275,947...159,290,383
Ensembl chr 3:159,275,947...159,290,383 		JBrowse link
G Dab2 DAB adaptor protein 2 disease_progression ISO protein:decreased expression:lung (human) RGD PMID:21496867 RGD:150530293 NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476 		JBrowse link
G Dab2ip DAB2 interacting protein sexual_dimorphism ISO DNA:SNP:intron 1:97906C>A (rs1571801) (human) RGD PMID:22046421 RGD:151665197 NCBI chr 3:18,915,290...19,086,282
Ensembl chr 3:18,915,290...19,086,280 		JBrowse link
G Dagla diacylglycerol lipase, alpha ISO DNA:SNP:rs60507107 (human) RGD PMID:25592173 RGD:151356746 NCBI chr 1:206,890,635...206,947,332
Ensembl chr 1:206,890,638...206,947,232 		JBrowse link
G Dhfr dihydrofolate reductase ISO ClinVar Annotator: match by term: Lung cancer ClinVar PMID:28492532 NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713 		JBrowse link
G Dicer1 dicer 1 ribonuclease III exacerbates ISO RGD PMID:19903759 RGD:149735199 NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965 		JBrowse link
G Dnai7 dynein axonemal intermediate chain 7 ameliorates ISO DNA:missense mutation:CDS:p.N60S (mouse) RGD PMID:14583591 RGD:152998907 NCBI chr 4:178,143,499...178,179,871
Ensembl chr 4:178,143,500...178,179,980 		JBrowse link
G Dnmt1 DNA methyltransferase 1 disease_progression ISO protein:increased expression:lung:
protein:increased expression:lung (human)		 RGD PMID:24548441 PMID:21496867 RGD:9588658, RGD:150530293 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha disease_progression ISO protein:increased expression:lung: RGD PMID:24548441 RGD:9588658 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687 		JBrowse link
G Dnmt3b DNA methyltransferase 3 beta disease_progression ISO protein:increased expression:lung: RGD PMID:24548441 RGD:9588658 NCBI chr 3:142,130,592...142,169,124
Ensembl chr 3:142,130,592...142,169,124 		JBrowse link
G Drd4 dopamine receptor D4 ISO ClinVar Annotator: match by term: Lung cancer ClinVar NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553 		JBrowse link
G Dspp dentin sialophosphoprotein ISO ClinVar Annotator: match by term: Lung cancer ClinVar PMID:26467025 NCBI chr14:5,565,562...5,571,669
Ensembl chr14:5,565,629...5,571,672 		JBrowse link
G Dvl3 dishevelled segment polarity protein 3 ISO DNA:SNP:intron:rs1969253 (human) RGD PMID:29193083 RGD:153297750 NCBI chr11:80,365,446...80,382,641
Ensembl chr11:80,366,117...80,382,462 		JBrowse link
G Egfr epidermal growth factor receptor ISO ClinVar Annotator: match by term: Lung cancer | ClinVar Annotator: match by term: Lung cancer, somatic ClinVar PMID:11423618 PMID:15118073 PMID:15118125 PMID:15272417 PMID:15329413 More... NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Epb41l3 erythrocyte membrane protein band 4.1-like 3 ISO ClinVar Annotator: match by term: Lung cancer ClinVar NCBI chr 9:109,056,178...109,260,607
Ensembl chr 9:109,016,113...109,260,607 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 ISO ClinVar Annotator: match by term: Lung cancer ClinVar PMID:1681519 PMID:2999974 PMID:3003577 PMID:8095488 PMID:24033266 More... NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078 		JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 ISO ClinVar Annotator: match by term: Lung cancer ClinVar NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595 		JBrowse link
G Ercc5 ERCC excision repair 5, endonuclease susceptibility ISO mRNA:decreased expression:lung (human) RGD PMID:10910954 RGD:155260338 NCBI chr 9:46,309,477...46,354,478
Ensembl chr 9:46,309,389...46,354,472 		JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor susceptibility
disease_progression
no_association		 ISO DNA:point mutation:promoter::c.-6530C>G (rs3793784) (human)
ClinVar Annotator: match by term: LUNG CANCER, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Lung cancer | ClinVar Annotator: match by term: Lung cancer, somatic
mRNA:decreased expression:lung (human)
DNA:SNPs: :p.G399D, p.Q1413R (human)
DNA:SNPs: :multiple		 ClinVar
RGD		 PMID:9443879 PMID:10767341 PMID:16754848 PMID:17854076 PMID:18414213 More... RGD:11561791, RGD:155260338, RGD:11567235, RGD:11567231 NCBI chr16:7,764,983...7,835,587
Ensembl chr16:7,765,013...7,835,587 		JBrowse link
G Esco2 establishment of sister chromatid cohesion N-acetyltransferase 2 severity ISO RGD PMID:33573689 RGD:155791670 NCBI chr15:40,034,566...40,052,295
Ensembl chr15:40,034,568...40,055,306 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit susceptibility ISO DNA:SNPs, haplotype: :rs6950683, rs3757441 (human) RGD PMID:19901851 RGD:126781717 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362 		JBrowse link
G Faslg Fas ligand ISO ClinVar Annotator: match by term: Lung cancer, somatic ClinVar PMID:17605793 PMID:25741868 PMID:28492532 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Fat1 FAT atypical cadherin 1 ISO ClinVar Annotator: match by term: Lung cancer ClinVar NCBI chr16:47,177,253...47,296,261
Ensembl chr16:47,177,248...47,296,107 		JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 ISO ClinVar Annotator: match by term: Lung cancer ClinVar NCBI chr 2:170,150,552...170,310,698
Ensembl chr 2:170,149,694...170,309,941 		JBrowse link
G Fgf9 fibroblast growth factor 9 ISS OMIM:211980 | OMIM:608935 | OMIM:612571 | OMIM:612593 | OMIM:614210 MouseDO NCBI chr15:32,208,993...32,254,952
Ensembl chr15:32,210,074...32,253,309 		JBrowse link
G Foxa1 forkhead box A1 disease_progression ISO RGD PMID:31221478 RGD:151665930 NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188 		JBrowse link
G Foxm1 forkhead box M1 ISS OMIM:211980 | OMIM:608935 | OMIM:612571 | OMIM:612593 | OMIM:614210 MouseDO NCBI chr 4:161,639,561...161,652,012
Ensembl chr 4:161,638,816...161,650,684 		JBrowse link
G Gata1 GATA binding protein 1 ISO mRNA:increased expression:regulatory T cell:lung associated T cell RGD PMID:28814673 RGD:149735197 NCBI chr  X:14,529,706...14,537,530
Ensembl chr  X:14,529,702...14,537,530 		JBrowse link
G Gnaq G protein subunit alpha q ISO ClinVar Annotator: match by term: Lung cancer ClinVar NCBI chr 1:213,425,631...213,671,947
Ensembl chr 1:213,424,465...213,667,672 		JBrowse link
G Gpx1 glutathione peroxidase 1 susceptibility
exacerbates		 ISO DNA:missense mutation:CDS:p.P198L (human)
DNA:missense mutation:CDS: (rs1050450) (human)
DNA:mutations:multiple (human)		 RGD PMID:16615267 PMID:23516596 PMID:15192016 PMID:32850411 PMID:11103801 RGD:152023634, RGD:152998903, RGD:152995506, RGD:152995450, RGD:152995449 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Gpx3 glutathione peroxidase 3 treatment ISO RGD PMID:26767034 PMID:33255360 RGD:151708707, RGD:151708705 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 resistance ISO RGD PMID:19428374 RGD:4140941 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Gstt1 glutathione S-transferase theta 1 susceptibility ISO DNA:deletion: : RGD PMID:20542754 RGD:4140924 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585 		JBrowse link
G Hnrnpl heterogeneous nuclear ribonucleoprotein L severity ISO human gene in a mouse model RGD PMID:20972334 RGD:9999427 NCBI chr 1:84,098,558...84,111,568
Ensembl chr 1:84,100,879...84,111,553 		JBrowse link
G Hp haptoglobin IEP RGD PMID:19794824 RGD:11041857 NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523 		JBrowse link
G Hs3st2 heparan sulfate-glucosamine 3-sulfotransferase 2 ISO DNA:hypermethylation:promoter (human) RGD PMID:12527896 RGD:2317633 NCBI chr 1:175,956,161...176,077,400
Ensembl chr 1:175,956,157...176,077,399 		JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 ISO RGD PMID:30128035 RGD:149735564 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025 		JBrowse link
G Il1r2 interleukin 1 receptor type 2 susceptibility ISO DNA:SNP:CDS:multiple (human) RGD PMID:30895747 RGD:152998976 NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725 		JBrowse link
G Irs4 insulin receptor substrate 4 treatment ISO human cells in mouse model RGD PMID:33894221 RGD:151347872 NCBI chr  X:105,344,016...105,359,985 JBrowse link
G Kdm4a lysine demethylase 4A ISO protein:increased expression:lung (human) RGD PMID:23168260 RGD:9587434 NCBI chr 5:131,672,754...131,719,534
Ensembl chr 5:131,672,754...131,719,501 		JBrowse link
G Kdm4b lysine demethylase 4B ISO mRNA, protein:increased expression:lung (human) RGD PMID:21930796 RGD:9587740 NCBI chr 9:1,158,737...1,237,228
Ensembl chr 9:1,158,752...1,236,543 		JBrowse link
G Kdm6a lysine demethylase 6A exacerbates ISO RGD PMID:29632194 RGD:150429738 NCBI chr  X:4,337,466...4,477,100
Ensembl chr  X:4,337,750...4,477,062 		JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 ISO ClinVar Annotator: match by term: Lung cancer ClinVar NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862 		JBrowse link
G Kmt2c lysine methyltransferase 2C ISO ClinVar Annotator: match by term: Lung cancer | ClinVar Annotator: match by term: Lung cancer, somatic ClinVar PMID:25741868 PMID:28492532 NCBI chr 4:9,620,638...9,834,787
Ensembl chr 4:9,609,627...9,833,539 		JBrowse link
G Kmt2d lysine methyltransferase 2D ISO ClinVar Annotator: match by term: Lung cancer ClinVar PMID:25741868 NCBI chr 7:129,980,744...130,022,088
Ensembl chr 7:129,962,887...130,020,325 		JBrowse link
G Kras KRAS proto-oncogene, GTPase ISS
ISO		 OMIM:211980 | OMIM:608935 | OMIM:612571 | OMIM:612593 | OMIM:614210
ClinVar Annotator: match by term: Lung cancer, somatic
protein:increased expression:lung (human)		 MouseDO
ClinVar
RGD		 PMID:2278970 PMID:3122217 PMID:12460918 PMID:15696205 PMID:16361624 More... RGD:153344580 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Lrp1b LDL receptor related protein 1B severity ISO DNA:mutations: :multiple (human)
ClinVar Annotator: match by term: Lung cancer		 ClinVar
RGD		 PMID:33219256 RGD:150429789 NCBI chr 3:24,594,302...26,715,037
Ensembl chr 3:24,594,991...26,715,505 		JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 ameliorates ISO DNA:SNP:promoter: -1304T>G (rs3826392) (human) RGD PMID:20554746 RGD:150429822 NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993 		JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 exacerbates ISO RGD PMID:26300007 RGD:11535492 NCBI chr17:53,382,908...53,403,216
Ensembl chr17:53,383,131...53,403,216 		JBrowse link
G Mat2a methionine adenosyltransferase 2A treatment ISO human cells in mouse model RGD PMID:34258296 RGD:153350142 NCBI chr 4:104,489,877...104,495,447
Ensembl chr 4:104,488,466...104,495,493 		JBrowse link
G Mbd1 methyl-CpG binding domain protein 1 susceptibility ISO DNA:snp::c.1221+135T>A (rs140689) (human)
DNA:snps, deletion:promoter, cds:g.-634G>A, g.-501delT, p.P401A (human)		 RGD PMID:18668384 PMID:16284366 RGD:9588657, RGD:9588651 NCBI chr18:67,869,870...67,884,501
Ensembl chr18:67,869,992...67,886,554 		JBrowse link
G Mbd4 methyl-CpG binding domain 4 DNA glycosylase susceptibility ISO DNA:snp:cds:p.E346K (rs140693) (human) RGD PMID:18495292 RGD:9588970 NCBI chr 4:148,893,049...148,904,833
Ensembl chr 4:148,894,280...148,904,982 		JBrowse link
G Mbl2 mannose binding lectin 2 susceptibility ISO DNA:polymorphisms:multiple (human) RGD PMID:19959685 RGD:4889433 NCBI chr 1:228,016,439...228,024,736 JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member ameliorates ISO human cells in mouse model
protein:increased expression:lung (human)
DNA:SNP:promoter:-190indel, -235C>A, (rs3831987,rs3738484) 		RGD PMID:31662324 PMID:28776569 PMID:21887682 RGD:151356915, RGD:151356930, RGD:151356991 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303 		JBrowse link
G Mef2d myocyte enhancer factor 2D treatment ISO human cells in mouse model RGD PMID:25472877 RGD:151361106 NCBI chr 2:173,606,054...173,635,620
Ensembl chr 2:173,606,490...173,634,457 		JBrowse link
G Mir122 microRNA 122 treatment ISO human cells in mouse model RGD PMID:25472877 RGD:151361106 NCBI chr18:58,758,703...58,758,787 JBrowse link
G Mir127 microRNA 127 ISO RNA:increased expression:lung (human) RGD PMID:20237410 RGD:152995484 NCBI chr 6:128,546,215...128,546,311
Ensembl chr 6:128,546,215...128,546,311 		JBrowse link
G Mir136 microRNA 136 ameliorates ISO RNA:increased expression:lung (human)
human cells in mouse model		 RGD PMID:20237410 PMID:34258296 RGD:152995484, RGD:153350142 NCBI chr 6:128,549,096...128,549,177
Ensembl chr 6:128,549,096...128,549,177 		JBrowse link
G Mir152 microRNA 152 ISO miRNA:increased expression:plasma RGD PMID:26958084 RGD:21066332 NCBI chr10:81,832,936...81,833,020
Ensembl chr10:81,832,936...81,833,020 		JBrowse link
G Mir193a microRNA 193a ameliorates
treatment		 ISO human cells in mouse model
DNA:hypermethylation		 RGD PMID:27821145 PMID:27669434 PMID:35289739 PMID:29183007 RGD:153344578, RGD:153344606, RGD:153344587, RGD:153344580 NCBI chr10:64,672,343...64,672,454
Ensembl chr10:64,672,343...64,672,454 		JBrowse link
G Mir205 microRNA 205 ISO RNA:increased expression:lung (human) RGD PMID:20237410 RGD:152995484 NCBI chr13:105,035,878...105,035,985
Ensembl chr13:105,035,878...105,035,985 		JBrowse link
G Mir21 microRNA 21 ameliorates ISO RNA:increased expression:blood serum (human) RGD PMID:22618808 PMID:22638884 RGD:152998905, RGD:152998900 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mir222 microRNA 222 ameliorates ISO RGD PMID:26909602 RGD:151708998 NCBI chr  X:3,428,904...3,429,006
Ensembl chr  X:3,428,904...3,429,006 		JBrowse link
G Mir31 microRNA 31 disease_progression ISO RNA:increased expression:peripheral blood mononuclear cell (human)
RNA:increased expression:lung (human)		 RGD PMID:20237410 PMID:25765717 RGD:152995484, RGD:152998919 NCBI chr 5:103,599,038...103,599,143 JBrowse link
G Mir337 microRNA 337 ISO RNA:increased expression:lung (human) RGD PMID:20237410 RGD:152995484 NCBI chr 6:128,538,903...128,538,999
Ensembl chr 6:128,538,902...128,538,998 		JBrowse link
G Mir410 microRNA 410 ISO RNA:increased expression:lung (human) RGD PMID:20237410 RGD:152995484 NCBI chr 6:128,758,358...128,758,433
Ensembl chr 6:128,758,354...128,758,434 		JBrowse link
G Mir431 microRNA 431 ISO RNA:increased expression:lung (human) RGD PMID:20237410 RGD:152995484 NCBI chr 6:128,544,210...128,544,323
Ensembl chr 6:128,544,210...128,544,323 		JBrowse link
G Mir98 microRNA 98 treatment ISO RGD PMID:35289739 RGD:153344587 NCBI chr  X:20,981,235...20,981,342
Ensembl chr  X:20,981,235...20,981,342 		JBrowse link
G Mirlet7bhg Mirlet7b host gene susceptibility ISO DNA:SNPs:multiple RGD PMID:26199339 RGD:152998959
G Mki67 marker of proliferation Ki-67 ameliorates ISO human cells in mouse model RGD PMID:29183007 RGD:153344580 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762 		JBrowse link
G Mlh1 mutL homolog 1 susceptibility
no_association		 ISO DNA:SNP: :rs1800734 (human)
ClinVar Annotator: match by term: Lung cancer
DNA:SNP: :9452A>T (rs1540354) (human)
DNA:SNP:promoter:-93A>G (rs1800734) (human)		 ClinVar
RGD		 PMID:25420488 PMID:26845104 PMID:28492532 PMID:30702970 PMID:25252909 More... RGD:126848798, RGD:126848792, RGD:126848792 NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617 		JBrowse link
G Mmp1 matrix metallopeptidase 1 susceptibility ISO associated with Respiratory Tract Diseases
DNA:insertion:promoter:g.-1607insG (human)
DNA:insertion, haplotype:promoter:g.-1607insG (human)		 RGD PMID:15718477 PMID:11691799 PMID:19963114 RGD:5131088, RGD:7207021, RGD:4890379 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097 		JBrowse link
G Mmp3 matrix metallopeptidase 3 ISO protein:decreased expression:pleural fluid RGD PMID:20216542 RGD:5129491 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961 		JBrowse link
G Mpo myeloperoxidase ISO associated with Respiratory Tract Diseases
ClinVar Annotator: match by term: Lung cancer, protection against, in smokers		 ClinVar
RGD		 PMID:11087769 PMID:12915675 PMID:15023809 PMID:17304047 PMID:15718477 RGD:5131088 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Mpzl3 myelin protein zero-like 3 ISO DNA:SNP:UTR3:rs11216826 (human) RGD PMID:29193083 RGD:153297750 NCBI chr 8:45,360,475...45,380,662
Ensembl chr 8:45,349,054...45,380,662 		JBrowse link
G Msh2 mutS homolog 2 susceptibility ISO DNA:SNP: :rs2303425 (human) RGD PMID:25252909 RGD:126848798 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938 		JBrowse link
G Msh3 mutS homolog 3 ISO ClinVar Annotator: match by term: Lung cancer ClinVar PMID:28492532 NCBI chr 2:23,444,326...23,585,777 JBrowse link
G Muc16 mucin 16, cell surface associated ISO ClinVar Annotator: match by term: Lung cancer ClinVar NCBI chr 8:16,164,531...16,323,126 JBrowse link
G Muc19 mucin 19, oligomeric ISO ClinVar Annotator: match by term: Lung cancer ClinVar NCBI chr 7:123,017,896...123,139,053
Ensembl chr 7:123,017,896...123,139,053 		JBrowse link
G Muc2 mucin 2, oligomeric mucus/gel-forming ISO ClinVar Annotator: match by term: Lung cancer ClinVar NCBI chr 1:196,796,257...196,831,740
Ensembl chr 1:196,799,517...196,831,756 		JBrowse link
G Muc3a mucin 3A, cell surface associated ISO ClinVar Annotator: match by term: Lung cancer ClinVar NCBI chr12:19,455,783...19,462,165
Ensembl chr12:19,446,094...19,460,522 		JBrowse link
G Muc4 mucin 4, cell surface associated ISO ClinVar Annotator: match by term: Lung cancer ClinVar NCBI chr11:68,008,245...68,053,229 JBrowse link
G Muc6 mucin 6, oligomeric mucus/gel-forming ISO ClinVar Annotator: match by term: Lung cancer ClinVar NCBI chr 1:196,726,678...196,764,842
Ensembl chr 1:196,726,807...196,764,842 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor treatment ISO human cells in mouse model RGD PMID:32051824 RGD:150530284 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor exacerbates ISO human cell line in a mouse model RGD PMID:22938463 RGD:150521529 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Nat2 N-acetyltransferase 2 susceptibility
no_association		 ISO DNA:polymorphisms: : RGD PMID:19558213 PMID:15808403 RGD:5131605, RGD:5131861 NCBI chr16:22,207,362...22,238,513
Ensembl chr16:22,208,194...22,238,520 		JBrowse link
G Ncoa6 nuclear receptor coactivator 6 ISO DNA:amplification:cds (human) RGD PMID:10567404 RGD:9590137 NCBI chr 3:143,890,896...143,961,916
Ensembl chr 3:143,890,896...143,952,268 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 ISO ClinVar Annotator: match by term: Lung cancer ClinVar NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 exacerbates
disease_progression		 ISO RGD PMID:26300007 PMID:26300007 RGD:11535492, RGD:11535492 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nfkbia NFKB inhibitor alpha susceptibility ISO DNA:polymorphisms:promoter:-826C>T,-881A>G (human) RGD PMID:26870106 RGD:13793394 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 ISO ClinVar Annotator: match by term: Lung cancer ClinVar NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 susceptibility ISO DNA:insertion: : 3020_3021insC (human) RGD PMID:16267612 RGD:5131514 NCBI chr19:18,379,720...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Palb2 partner and localizer of BRCA2 ISO ClinVar Annotator: match by term: Lung cancer ClinVar PMID:17200668 PMID:17200671 PMID:17200672 PMID:24136930 PMID:25099575 More... NCBI chr 1:176,665,076...176,689,053
Ensembl chr 1:176,665,076...176,688,990 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha ISO ClinVar Annotator: match by term: Lung cancer, somatic ClinVar PMID:19366826 PMID:25157968 PMID:25741868 PMID:26619011 NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032 		JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma ISO ClinVar Annotator: match by term: Lung cancer ClinVar NCBI chr 6:48,766,778...48,802,098
Ensembl chr 6:48,766,864...48,802,043 		JBrowse link
G Plcg1 phospholipase C, gamma 1 exacerbates ISO RGD PMID:33077911 RGD:151356960 NCBI chr 3:149,385,587...149,416,330
Ensembl chr 3:149,385,587...149,416,330 		JBrowse link
G Pml PML nuclear body scaffold ameliorates ISO RGD PMID:25486572 RGD:41404692 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971 		JBrowse link
G Pole DNA polymerase epsilon, catalytic subunit severity ISO DNA:missense mutation:CDS:p.A252V (human) RGD PMID:17855454 RGD:11567235 NCBI chr12:46,345,420...46,393,984
Ensembl chr12:46,345,420...46,393,939 		JBrowse link
G Pot1 protection of telomeres 1 ISO DNA:SNP: :rs116895242 (human)
DNA:SNP: :p.V326A (rs75932146) (human)
DNA:SNP: : rs10244817 (human)		 RGD PMID:27459707 PMID:32514122 PMID:19285750 RGD:151356949, RGD:151356948, RGD:151356947 NCBI chr 4:54,205,330...54,263,137
Ensembl chr 4:54,205,332...54,263,042 		JBrowse link
G Prdm1 PR/SET domain 1 disease_progression ISO RGD PMID:28378641 RGD:150530469 NCBI chr20:47,959,858...47,981,488
Ensembl chr20:47,959,858...47,981,488 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase ISO ClinVar Annotator: match by term: Lung cancer, somatic ClinVar PMID:25741868 PMID:25939424 PMID:28492532 PMID:28862745 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IMP RGD PMID:21303331 RGD:5135048 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rac1 Rac family small GTPase 1 treatment ISO DNA:SNPs:enhancers, intron: (rs836554, rs4720672, rs12536544) (human) RGD PMID:27299748 RGD:155230814 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251 		JBrowse link
G Rad52 RAD52 homolog, DNA repair protein susceptibility ISO DNA:SNP,haplotype:
DNA:SNP: (rs4766394) (human)		 RGD PMID:18449888 PMID:22382497 RGD:151660351, RGD:151660503 NCBI chr 4:153,106,062...153,128,598
Ensembl chr 4:153,106,062...153,128,207 		JBrowse link
G Rbm10 RNA binding motif protein 10 onset ISO RGD PMID:33219256 RGD:150429789 NCBI chr  X:1,540,399...1,572,571
Ensembl chr  X:1,540,398...1,572,575 		JBrowse link
G Recql RecQ like helicase ISO RGD PMID:18422747 RGD:2317370 NCBI chr 4:175,308,337...175,332,965
Ensembl chr 4:175,304,117...175,332,945 		JBrowse link
G Reln reelin ISO ClinVar Annotator: match by term: Lung cancer ClinVar NCBI chr 4:12,736,177...13,162,956
Ensembl chr 4:12,736,130...13,162,211 		JBrowse link
G Rictor RPTOR independent companion of MTOR, complex 2 ISO DNA:amplification: :lung (human) RGD PMID:26370156 RGD:11535413 NCBI chr 2:55,811,877...55,903,893
Ensembl chr 2:55,811,322...55,901,426 		JBrowse link
G Rnaset2 ribonuclease T2 ISO DNA:SNP:intergenic:rs444210 (human) RGD PMID:29193083 RGD:153297750 NCBI chr 1:52,576,344...52,603,151
Ensembl chr 1:52,585,929...52,603,147 		JBrowse link
G Robo1 roundabout guidance receptor 1 ISS OMIM:211980 | OMIM:608935 | OMIM:612571 | OMIM:612593 | OMIM:614210 MouseDO NCBI chr11:10,580,863...11,621,672
Ensembl chr11:10,580,908...11,620,203 		JBrowse link
G Rtel1 regulator of telomere elongation helicase 1 susceptibility
ameliorates		 ISO DNA:SNP:cds:rs7261546|rs6062299|rs3787098 (human)
DNA:SNP:cds:rs2738789 (human)		 RGD PMID:27765928 PMID:27765928 RGD:152993553, RGD:152993553 NCBI chr 3:168,427,247...168,465,349
Ensembl chr 3:168,419,579...168,465,348 		JBrowse link
G Setdb1 SET domain bifurcated histone lysine methyltransferase 1 severity ISO human gene in a mouse model RGD PMID:23770855 RGD:9590160 NCBI chr 2:182,898,738...182,930,283
Ensembl chr 2:182,898,738...182,930,506 		JBrowse link
G Sftpb surfactant protein B disease_progression ISO RGD PMID:24248694 PMID:28743125 RGD:151667422, RGD:151667423 NCBI chr 4:104,359,303...104,368,439
Ensembl chr 4:104,359,396...104,368,436 		JBrowse link
G Shox2 short stature homeobox 2 ISO RGD PMID:25331797 RGD:12859082 NCBI chr 2:151,217,049...151,227,180
Ensembl chr 2:151,217,552...151,227,143 		JBrowse link
G Slc25a5 solute carrier family 25 member 5 ISO ClinVar Annotator: match by term: Lung cancer ClinVar NCBI chr  X:116,031,896...116,034,963
Ensembl chr  X:116,031,803...116,034,967 		JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 ISO mRNA:increased expression:lung (human) RGD PMID:25625007 RGD:152995427 NCBI chr 4:174,551,463...174,619,988
Ensembl chr 4:174,551,480...174,619,981 		JBrowse link
G Smad3 SMAD family member 3 ISO ClinVar Annotator: match by term: Lung cancer ClinVar PMID:21515830 PMID:24465804 PMID:26253951 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
G Smad4 SMAD family member 4 ISO ClinVar Annotator: match by term: Lung cancer ClinVar PMID:21515830 PMID:24465805 PMID:26253951 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438 		JBrowse link
G Smad9 SMAD family member 9 ISO ClinVar Annotator: match by term: Lung cancer ClinVar PMID:21515830 PMID:24465803 PMID:26253951 NCBI chr 2:138,956,326...139,006,315
Ensembl chr 2:138,986,471...139,006,307 		JBrowse link
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 ISO ClinVar Annotator: match by term: Lung cancer ClinVar NCBI chr 8:20,167,717...20,258,975
Ensembl chr 8:20,167,717...20,258,975 		JBrowse link
G Sod2 superoxide dismutase 2 ISO RGD PMID:15213518 RGD:1581247 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sox30 SRY-box transcription factor 30 exacerbates ISO DNA:hypermethylation:lung: RGD PMID:25435374 PMID:25435374 RGD:151660338, RGD:151660338 NCBI chr10:30,417,499...30,446,441
Ensembl chr10:30,418,473...30,446,453 		JBrowse link
G Sox9 SRY-box transcription factor 9 disease_progression ISO mRNA:increased expression:lung RGD PMID:31221478