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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Respiratory Tract Neoplasms
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Accession:DOID:9003744 term browser browse the term
Definition:New abnormal growth of tissue in the RESPIRATORY SYSTEM.
Synonyms:exact_synonym: Respiratory Tract Neoplasm;   respiratory system neoplasm
 primary_id: MESH:D012142
 xref: EFO:0003853


show annotations for term's descendants           Sort by:
adenosquamous lung carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ttr transthyretin ISO protein:increased expression:lung (human) RGD PMID:26943652 RGD:151665207 NCBI chr18:12,216,684...12,225,972
Ensembl chr18:11,943,789...11,951,008 		JBrowse link
asbestos-related lung carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam28 ADAM metallopeptidase domain 28 ISO associated with lung adenocarcinoma ;mRNA:increased expression:lung RGD PMID:20544843 RGD:153298907 NCBI chr15:50,184,286...50,250,605
Ensembl chr15:42,944,467...43,840,672 		JBrowse link
G Kif5a kinesin family member 5A susceptibility ISO protein:increased expression:serum (human) RGD PMID:21231887 RGD:12793066 NCBI chr 7:64,937,210...64,974,339
Ensembl chr 7:63,049,424...63,092,858 		JBrowse link
G Rarb retinoic acid receptor, beta ISO DNA:hypomethylation:lung RGD PMID:28722770 RGD:13503322 NCBI chr15:10,837,252...11,482,037
Ensembl chr15:8,406,492...9,051,288 		JBrowse link
bronchiolo-alveolar adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alx4 ALX homeobox 4 ameliorates ISO RGD PMID:24037716 RGD:153344522 NCBI chr 3:100,067,052...100,103,624
Ensembl chr 3:79,611,719...79,648,260 		JBrowse link
G Ccnd1 cyclin D1 ISO protein:increased expression:lung RGD PMID:14674039 RGD:13434930 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Dnmt1 DNA methyltransferase 1 disease_progression ISO RGD PMID:19484794 RGD:4140940 NCBI chr 8:27,716,797...27,763,405
Ensembl chr 8:19,440,611...19,486,659 		JBrowse link
G Egfr epidermal growth factor receptor ISO
IMP		 DNA:snp:cds:p.T790M (human)
DNA:mutations:exons:
protein:increased expression:tumor (human)		 RGD PMID:15737014 PMID:26059825 PMID:21419590 RGD:5131465, RGD:11075076, RGD:5131630 NCBI chr14:95,378,626...95,551,358
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Egr1 early growth response 1 ISO mRNA:decreased expression:tumor (human) RGD PMID:11948124 RGD:5131942 NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 ISO DNA:hypermethylation:promoter (human) RGD PMID:19484794 RGD:4140940 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Kras KRAS proto-oncogene, GTPase IMP DNA:mutations:cds: RGD PMID:26059825 RGD:11075076 NCBI chr 4:179,916,255...179,949,613 JBrowse link
G Mir130a microRNA 130a ISO CTD Direct Evidence: marker/mechanism CTD PMID:25926378 NCBI chr 3:90,229,228...90,229,315
Ensembl chr 3:69,822,542...69,822,629 		JBrowse link
G Mir144 microRNA 144 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25926378 NCBI chr10:63,459,397...63,459,479
Ensembl chr10:62,961,348...62,961,430 		JBrowse link
G Mir19a microRNA 19a ISO CTD Direct Evidence: marker/mechanism CTD PMID:25926378 NCBI chr15:98,588,131...98,588,212
Ensembl chr15:92,180,912...92,180,993 		JBrowse link
G Mir345 microRNA 345 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25926378 NCBI chr 6:133,518,403...133,518,498
Ensembl chr 6:127,754,027...127,754,122 		JBrowse link
G Mir497 microRNA 497 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25926378 NCBI chr10:55,450,171...55,450,239
Ensembl chr10:54,951,505...54,951,584 		JBrowse link
G Tp53 tumor protein p53 IMP DNA:mutations:exons: RGD PMID:26059825 RGD:11075076 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
bronchus carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gstp1 glutathione S-transferase pi 1 ISO mRNA:decreased expression:bronchus, epithelial cell RGD PMID:10749130 RGD:4142527 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO protein:increased secretion:lung (human) RGD PMID:18764914 RGD:4145523 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Il10 interleukin 10 ISO protein:increased expression:lung RGD PMID:8030748 RGD:4143231 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO protein:increased expression, alternative forms:lung RGD PMID:8030748 RGD:4143231 NCBI chr 3:27,509,836...27,525,738
Ensembl chr 3:7,111,550...7,127,445 		JBrowse link
Carney Triad term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sdha succinate dehydrogenase complex flavoprotein subunit A ISO ClinVar Annotator: match by term: Carney triad | ClinVar Annotator: match by term: GASTRIC LEIOMYOSARCOMA, PULMONARY CHONDROMA, AND EXTRAADRENAL PARAGANGLIOMA ClinVar PMID:20484225 PMID:21505157 PMID:21752896 PMID:22955521 PMID:22974104 More... NCBI chr 1:30,764,553...30,789,523
Ensembl chr 1:28,940,164...28,961,535 		JBrowse link
G Sdhb succinate dehydrogenase complex iron sulfur subunit B ISO ClinVar Annotator: match by term: GASTRIC LEIOMYOSARCOMA, PULMONARY CHONDROMA, AND EXTRAADRENAL PARAGANGLIOMA ClinVar PMID:15987702 PMID:16288654 PMID:16317055 PMID:16912137 PMID:16916404 More... NCBI chr 5:158,547,775...158,568,589
Ensembl chr 5:153,264,899...153,314,293 		JBrowse link
G Sdhc succinate dehydrogenase complex subunit C ISO ClinVar Annotator: match by term: Carney triad | ClinVar Annotator: match by term: GASTRIC LEIOMYOSARCOMA, PULMONARY CHONDROMA, AND EXTRAADRENAL PARAGANGLIOMA ClinVar PMID:9536098 PMID:12658451 PMID:17576681 PMID:17667967 PMID:17804857 More... NCBI chr13:86,077,133...86,098,025
Ensembl chr13:83,544,652...83,566,253 		JBrowse link
DICER1 syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asb2 ankyrin repeat and SOCS box-containing 2 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:128,239,550...128,275,833
Ensembl chr 6:122,474,756...122,510,854 		JBrowse link
G Btbd7 BTB domain containing 7 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:127,685,185...127,774,947
Ensembl chr 6:121,923,023...121,972,405 		JBrowse link
G Cox8c cytochrome c oxidase subunit 8C ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:127,793,379...127,794,702
Ensembl chr 6:122,028,566...122,029,889 		JBrowse link
G Ddx24 DEAD-box helicase 24 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:128,329,554...128,346,818
Ensembl chr 6:122,564,767...122,581,927 		JBrowse link
G Dicer1 dicer 1 ribonuclease III ISO ClinVar Annotator: match by term: DICER1 syndrome OMIM
ClinVar		 PMID:9295070 PMID:9345104 PMID:9536098 PMID:15242644 PMID:15987463 More... NCBI chr 6:129,392,298...129,457,252
Ensembl chr 6:123,631,250...123,693,965 		JBrowse link
G Fam181a family with sequence similarity 181, member A ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:128,230,171...128,236,193
Ensembl chr 6:122,465,391...122,471,397 		JBrowse link
G Gsc goosecoid homeobox ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:129,152,836...129,154,875
Ensembl chr 6:123,388,072...123,390,111 		JBrowse link
G Ifi27 interferon, alpha-inducible protein 27 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:128,355,312...128,361,783
Ensembl chr 6:122,590,472...122,779,294 		JBrowse link
G Ifi27l2a interferon, alpha-inducible protein 27 like 2A ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:128,363,658...128,365,144
Ensembl chr 6:122,598,872...122,600,360 		JBrowse link
G Otub2 OTU deubiquitinase, ubiquitin aldehyde binding 2 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:128,309,863...128,328,444
Ensembl chr 6:122,545,061...122,563,644 		JBrowse link
G Ppp4r4 protein phosphatase 4, regulatory subunit 4 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:128,427,884...128,518,776
Ensembl chr 6:122,663,344...122,753,384 		JBrowse link
G Prima1 proline rich membrane anchor 1 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:128,094,686...128,155,592
Ensembl chr 6:122,338,370...122,389,921 		JBrowse link
G Serpina1 serpin family A member 1 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:128,631,101...128,653,125
Ensembl chr 6:122,866,312...122,888,339 		JBrowse link
G Serpina10 serpin family A member 10 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:128,520,894...128,529,332
Ensembl chr 6:122,756,108...122,764,544 		JBrowse link
G Serpina11 serpin family A member 11 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:128,668,030...128,677,476
Ensembl chr 6:122,903,250...122,912,670 		JBrowse link
G Serpina12 serpin family A member 12 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:128,717,334...128,732,049
Ensembl chr 6:122,952,552...122,967,271 		JBrowse link
G Serpina1f serpin family A member 1F ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:128,585,697...128,591,902
Ensembl chr 6:122,820,907...122,827,112 		JBrowse link
G Serpina3n serpin family A member 3N ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:129,088,392...129,095,950
Ensembl chr 6:123,323,629...123,332,433 		JBrowse link
G Serpina4 serpin family A member 4 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:128,764,738...128,773,858
Ensembl chr 6:122,999,900...123,009,082 		JBrowse link
G Serpina5 serpin family A member 5 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:128,774,006...128,793,187
Ensembl chr 6:123,023,306...123,028,407 		JBrowse link
G Serpina6 serpin family A member 6 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:128,544,828...128,555,064
Ensembl chr 6:122,780,043...122,790,349 		JBrowse link
G Serpina9 serpin family A member 9 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:122,918,819...122,936,000
Ensembl chr 6:122,918,880...122,936,000 		JBrowse link
G Ubr7 ubiquitin protein ligase E3 component n-recognin 7 ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:127,663,454...127,683,302
Ensembl chr 6:121,898,623...121,918,477 		JBrowse link
G Unc79 unc-79 homolog, NALCN channel complex subunit ISO ClinVar Annotator: match by term: DICER1 syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:127,841,671...128,092,380
Ensembl chr 6:122,080,308...122,327,591 		JBrowse link
glottis squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wrap53 WD repeat containing, antisense to TP53 disease_progression ISO RGD PMID:28849066 RGD:21081521 NCBI chr10:54,780,873...54,797,919
Ensembl chr10:54,282,105...54,298,929 		JBrowse link
large cell neuroendocrine carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc7a5 solute carrier family 7 member 5 disease_progression ISO RGD PMID:18440724 RGD:151361285 NCBI chr19:66,843,808...66,872,412
Ensembl chr19:49,935,220...49,963,823 		JBrowse link
laryngeal carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ackr3 atypical chemokine receptor 3 disease_progression ISO protein:increased expression:larynx (human) RGD PMID:16494043 RGD:152025548 NCBI chr 9:98,247,300...98,258,877
Ensembl chr 9:90,799,686...90,811,237 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 disease_progression ISO protein:increased expression:larynx (human) RGD PMID:16494043 RGD:152025548 NCBI chr13:42,630,383...42,634,288
Ensembl chr13:40,077,976...40,081,883 		JBrowse link
G Kmt2c lysine methyltransferase 2C ISO mRNA:decreased expression:larynx RGD PMID:25633166 RGD:151356763 NCBI chr 4:10,353,698...10,755,965
Ensembl chr 4:9,609,627...9,833,539 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 severity ISO RGD PMID:20164024 RGD:150573814 NCBI chr10:5,389,574...5,391,265
Ensembl chr10:4,882,560...4,884,383 		JBrowse link
G Traf6 TNF receptor associated factor 6 disease_progression ISO RGD PMID:20164024 RGD:150573814 NCBI chr 3:108,418,537...108,443,330
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
G Ubr5 ubiquitin protein ligase E3 component n-recognin 5 exacerbates ISO mRNA, protein:increased expression:larynx (human) RGD PMID:32468011 RGD:151665191 NCBI chr 7:71,000,197...71,109,841
Ensembl chr 7:69,116,761...69,224,903 		JBrowse link
G Xrcc1 X-ray repair cross complementing 1 susceptibility ISO DNA:missense mutation:cds: p.R280H (human)
DNA:SNPs, haplotype:: (rs3213403, rs1799778, rs3213282) (human) 		RGD PMID:27808358 PMID:24956286 RGD:151236313, RGD:151236314 NCBI chr 1:89,268,721...89,296,619
Ensembl chr 1:80,141,207...80,168,701 		JBrowse link
Laryngeal Neoplasms term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:18500343 NCBI chr 2:226,748,724...226,763,183
Ensembl chr 2:226,741,788...226,763,182 		JBrowse link
G Egfr epidermal growth factor receptor severity ISO protein:increased expression:tumor (human) RGD PMID:8883413 RGD:5131485 NCBI chr14:95,378,626...95,551,358
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit susceptibility ISO DNA:snp:exon:c.354T>C (human) (rs11615) RGD PMID:24582975 RGD:13207310 NCBI chr 1:88,099,308...88,135,966
Ensembl chr 1:78,996,390...79,007,963 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 ISO protein:increased expression:larynx RGD PMID:18335753 RGD:4140949 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Mir10a microRNA 10a sexual_dimorphism ISO miRNA:decreased expression:larynx epithelium (human) RGD PMID:25266939 RGD:153344531 NCBI chr10:81,779,709...81,779,818
Ensembl chr10:81,283,171...81,283,280 		JBrowse link
G Mir34c microRNA 34c sexual_dimorphism ISO miRNA:increased expression:larynx epithelium (human) RGD PMID:25266939 RGD:153344531 NCBI chr 8:60,306,091...60,306,167
Ensembl chr 8:51,409,726...51,409,802 		JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO RGD PMID:17786346 RGD:5130203 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Nat1 N-acetyltransferase 1 susceptibility ISO DNA:polymorphism: : RGD PMID:12037388 RGD:5131864 NCBI chr16:26,984,882...27,005,194
Ensembl chr16:22,208,194...22,238,520 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 severity ISO protein:increased expression:larynx RGD PMID:20429377 RGD:5135434 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Spp1 secreted phosphoprotein 1 ISO RGD PMID:16299231 RGD:1581365 NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
Laryngeal Papillomatosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO RGD PMID:19736197 RGD:5135499 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Serpina3n serpin family A member 3N ISO protein:decreased expression:serum RGD PMID:16273852 RGD:5147435 NCBI chr 6:129,088,392...129,095,950
Ensembl chr 6:123,323,629...123,332,433 		JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member ISO RGD PMID:10618282 RGD:5147846 NCBI chr20:4,658,171...4,668,543
Ensembl chr20:4,656,263...4,666,901 		JBrowse link
laryngeal squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase ISO protein:decreased activity:larynx RGD PMID:8138195 RGD:152995273 NCBI chr 3:172,818,174...172,842,283
Ensembl chr 3:152,398,747...152,447,088 		JBrowse link
G Cat catalase ISO protein:increased activity:larynx RGD PMID:8138195 RGD:152995273 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cdc73 cell division cycle 73 disease_progression ISO protein:decreased expression:larynx (human) RGD PMID:27334641 RGD:150539447 NCBI chr13:57,897,924...58,000,031
Ensembl chr13:55,357,226...55,449,656 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A ISO RGD PMID:15646812 RGD:8662837 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Chd4 chromodomain helicase DNA binding protein 4 exacerbates ISO mRNA:increased expression:larynx (human) RGD PMID:33315534 RGD:153323310 NCBI chr 4:159,584,623...159,617,867
Ensembl chr 4:157,899,391...157,931,541 		JBrowse link
G Egfr epidermal growth factor receptor disease_progression ISO RGD PMID:22549618 RGD:126790474 NCBI chr14:95,378,626...95,551,358
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 disease_progression ISO RGD PMID:22549618 RGD:126790474 NCBI chr10:83,907,491...83,931,365
Ensembl chr10:83,411,313...83,435,078 		JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 disease_progression ISO RGD PMID:22549618 RGD:126790474 NCBI chr 7:1,579,079...1,600,379
Ensembl chr 7:996,225...1,015,525 		JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 disease_progression ISO RGD PMID:22549618 RGD:126790474 NCBI chr 9:76,973,386...78,045,633
Ensembl chr 9:69,531,481...70,596,595 		JBrowse link
G Foxl2 forkhead box L2 exacerbates ISO mRNA:increased expression:larynx (human) RGD PMID:32517588 RGD:151667913 NCBI chr 8:108,392,466...108,395,553
Ensembl chr 8:99,513,303...99,514,427 		JBrowse link
G Gpx1 glutathione peroxidase 1 disease_progression
no_association		 ISO protein:increased expression:larynx (human)
DNA:missense mutation:CDS:p.P198L (human)
DNA:missense mutation:CDS:p.P198L (rs1050450) (human)		 RGD PMID:28641905 PMID:24074040 PMID:27188866 RGD:152995454, RGD:152995493, RGD:152995455 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 severity ISO associated with Neoplasm Metastasis; protein:mRNA,increased expression:larynx epithelium (human) RGD PMID:19513509 RGD:150429781 NCBI chr10:50,842,348...50,947,063
Ensembl chr10:50,344,915...50,447,993 		JBrowse link
G Mir10a microRNA 10a severity ISO miRNA:decreased expression:blood serum (human) RGD PMID:35117730 RGD:153344530 NCBI chr10:81,779,709...81,779,818
Ensembl chr10:81,283,171...81,283,280 		JBrowse link
G Mir136 microRNA 136 ISO RNA:decreased expression:larynx (human) RGD PMID:32014687 RGD:153344610 NCBI chr 6:134,331,335...134,331,416
Ensembl chr 6:128,549,096...128,549,177 		JBrowse link
G Mir21 microRNA 21 exacerbates ISO miRNA:increased expression:blood serum (human) RGD PMID:35117730 RGD:153344530 NCBI chr10:71,902,600...71,902,691
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mir31 microRNA 31 disease_progression ISO RNA:decreased expression:mucosa of larynx (human) RGD PMID:29737563 RGD:152998933 NCBI chr 5:108,714,849...108,714,954 JBrowse link
G Mlh1 mutL homolog 1 disease_progression ISO mRNA:decreased expression:larynx RGD PMID:23787767 RGD:126848783 NCBI chr 8:120,074,871...120,112,109
Ensembl chr 8:111,196,468...111,233,617 		JBrowse link
G Mmp2 matrix metallopeptidase 2 ISO RGD PMID:17786346 RGD:5130203 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Msh2 mutS homolog 2 disease_progression ISO mRNA:decreased expression:larynx RGD PMID:23787767 RGD:126848783 NCBI chr 6:12,567,368...12,626,534
Ensembl chr 6:6,813,795...6,872,938 		JBrowse link
G Nat2 N-acetyltransferase 2 susceptibility ISO DNA:polymorphisms: : RGD PMID:19922706 PMID:16155914 RGD:5131602, RGD:5131856 NCBI chr16:26,974,874...27,005,191
Ensembl chr16:22,208,194...22,238,520 		JBrowse link
G Plcg1 phospholipase C, gamma 1 ameliorates ISO mRNA:increased expression:larynx (human) RGD PMID:33466212 RGD:151665160 NCBI chr 3:169,805,299...169,836,040
Ensembl chr 3:149,385,587...149,416,330 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit severity ISO associated with Neoplasm Metastasis; protein:mRNA,increased expression:larynx epithelium (human) RGD PMID:19513509 RGD:150429781 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Xdh xanthine dehydrogenase ISO protein:increased activity:larynx RGD PMID:8138195 RGD:152995273 NCBI chr 6:27,282,319...27,344,022
Ensembl chr 6:21,530,113...21,592,268 		JBrowse link
G Xrcc1 X-ray repair cross complementing 1 ISO ClinVar Annotator: match by term: Laryngeal squamous cell carcinoma ClinVar NCBI chr 1:89,268,721...89,296,619
Ensembl chr 1:80,141,207...80,168,701 		JBrowse link
larynx cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cxcl12 C-X-C motif chemokine ligand 12 exacerbates ISO protein:increased expression: mucosa of larynx (human) RGD PMID:23259294 RGD:152177474 NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 exacerbates ISO protein:increased expression: mucosa of larynx (human) RGD PMID:23259294 RGD:152177474 NCBI chr13:42,630,383...42,634,288
Ensembl chr13:40,077,976...40,081,883 		JBrowse link
G Ercc5 ERCC excision repair 5, endonuclease susceptibility ISO DNA:missense mutation:CDS:p.D1104H (human) RGD PMID:19444904 RGD:155260337 NCBI chr 9:53,801,471...53,846,611
Ensembl chr 9:46,309,389...46,354,472 		JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor susceptibility ISO DNA:missense mutation:CDS:p.R1230P (human) RGD PMID:19444904 RGD:155260337 NCBI chr16:7,771,311...7,841,895
Ensembl chr16:7,765,013...7,835,587 		JBrowse link
G Gpx1 glutathione peroxidase 1 susceptibility ISO DNA:missense mutation:CDS: (rs1050450) (human) RGD PMID:23516596 RGD:152998903 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 ISO DNA:deletion: : RGD PMID:19252926 RGD:4140943 NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Gstm3 glutathione S-transferase mu 3 ISO RGD PMID:10067818 RGD:5135043 NCBI chr 2:198,295,442...198,300,742
Ensembl chr 2:195,607,289...195,612,475 		JBrowse link
G Gstm5 glutathione S-transferase, mu 5 ISO RGD PMID:10067818 RGD:5135043 NCBI chr 2:198,219,769...198,222,732
Ensembl chr 2:195,531,495...195,534,553 		JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 ameliorates ISO mRNA:increased expression:larynx (human) RGD PMID:32791689 RGD:155256869 NCBI chr12:7,389,032...7,398,377
Ensembl chr12:2,591,219...2,604,222 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 onset ISO DNA:insertion:Cds: 3020_3021insC (human) RGD PMID:20223031 RGD:5131515 NCBI chr19:34,555,832...34,596,281
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Vegfa vascular endothelial growth factor A treatment ISO RGD PMID:20967863 RGD:126925200 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
lung adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1b ATP-binding cassette, sub-family B member 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 4:26,197,706...26,280,156
Ensembl chr 4:25,242,798...25,325,199 		JBrowse link
G Abce1 ATP binding cassette subfamily E member 1 severity ISO mRNA, protein:increased expression:lung (human) RGD PMID:18788636 RGD:11046260 NCBI chr19:45,109,880...45,134,819
Ensembl chr19:28,205,555...28,230,489 		JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr  X:110,739,633...110,803,416
Ensembl chr  X:105,942,799...106,006,427 		JBrowse link
G Adam19 ADAM metallopeptidase domain 19 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr10:30,992,713...31,084,455
Ensembl chr10:30,491,405...30,583,105 		JBrowse link
G Adam28 ADAM metallopeptidase domain 28 exacerbates
disease_progression
treatment		 ISO protein:increased expression:lung RGD PMID:29882245 PMID:26800504 PMID:30190423 PMID:20112342 RGD:153297792, RGD:11531771, RGD:153297795, RGD:153297794 NCBI chr15:50,184,286...50,250,605
Ensembl chr15:42,944,467...43,840,672 		JBrowse link
G Adamtsl3 ADAMTS-like 3 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr 1:145,698,004...146,006,195
Ensembl chr 1:136,288,793...136,596,986 		JBrowse link
G Adgrg6 adhesion G protein-coupled receptor G6 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr 1:10,633,004...10,774,685
Ensembl chr 1:8,812,904...8,954,123 		JBrowse link
G Ahcy adenosylhomocysteinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 3:164,029,338...164,044,562
Ensembl chr 3:143,569,094...143,584,393 		JBrowse link
G Ahr aryl hydrocarbon receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:12597446 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 disease_progression ISO RGD PMID:30727821 RGD:27226687 NCBI chr 5:135,329,605...135,367,037
Ensembl chr 5:130,092,732...130,113,674 		JBrowse link
G Alb albumin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:249,325,082...249,357,383
Ensembl chr 1:239,375,669...239,407,890 		JBrowse link
G Aldoa aldolase, fructose-bisphosphate A ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr 1:190,832,820...190,838,021
Ensembl chr 1:181,402,275...181,406,182 		JBrowse link
G Alk ALK receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Lung adenocarcinoma		 CTD
ClinVar		 PMID:20979469 PMID:21823889 PMID:22071784 PMID:22135231 PMID:22153831 More... NCBI chr 6:28,631,431...29,351,321
Ensembl chr 6:22,880,625...23,598,034 		JBrowse link
G Alox12b arachidonate 12-lipoxygenase, 12R type ISO CTD Direct Evidence: marker/mechanism CTD PMID:30258081 NCBI chr10:53,863,060...53,874,938
Ensembl chr10:53,863,060...53,874,938 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:30258081 NCBI chr 4:151,203,948...151,251,126
Ensembl chr 4:149,531,515...149,578,743 		JBrowse link
G Alx1 ALX homeobox 1 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr 7:40,044,185...40,063,778
Ensembl chr 7:38,147,117...38,177,220 		JBrowse link
G Alx4 ALX homeobox 4 disease_progression ISO RGD PMID:18978557 RGD:153350135 NCBI chr 3:100,067,052...100,103,624
Ensembl chr 3:79,611,719...79,648,260 		JBrowse link
G Anapc2 anaphase promoting complex subunit 2 severity ISO mRNA:decreased expression:lung (human) RGD PMID:12036940 RGD:14696682 NCBI chr 3:28,484,590...28,496,338
Ensembl chr 3:8,086,462...8,098,178 		JBrowse link
G Anp32a acidic nuclear phosphoprotein 32 family member A ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 8:71,724,578...71,760,922
Ensembl chr 8:62,827,456...62,865,443 		JBrowse link
G Anxa1 annexin A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr 1:227,287,713...227,306,739
Ensembl chr 1:217,861,175...217,877,343 		JBrowse link
G Anxa5 annexin A5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr 2:121,242,133...121,272,935
Ensembl chr 2:119,314,007...119,353,369 		JBrowse link
G Apc APC regulator of WNT signaling pathway ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr18:26,138,382...26,196,021
Ensembl chr18:25,864,222...25,922,696 		JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr15:26,618,146...26,620,330
Ensembl chr15:24,144,362...24,146,785 		JBrowse link
G Apoa1 apolipoprotein A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr 8:55,423,945...55,425,729
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G Apoc3 apolipoprotein C3 ISO protein:altered glycosylation:: RGD PMID:19322776 RGD:153344619 NCBI chr 8:55,428,172...55,430,352
Ensembl chr 8:46,531,478...46,533,583 		JBrowse link
G Aqp4 aquaporin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr18:6,782,389...6,799,034
Ensembl chr18:6,507,903...6,524,856 		JBrowse link
G Arg1 arginase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:22,295,093...22,307,720
Ensembl chr 1:20,475,968...20,488,422 		JBrowse link
G Arhgap35 Rho GTPase activating protein 35 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr 1:77,202,436...77,319,298
Ensembl chr 1:77,202,436...77,319,298 		JBrowse link
G Arhgap44 Rho GTPase activating protein 44 ISO mRNA:decreased expression:lung (human) RGD PMID:28527113 RGD:401901290 NCBI chr10:50,154,724...50,322,027
Ensembl chr10:49,655,584...49,824,297 		JBrowse link
G Atp5pd ATP synthase peripheral stalk subunit d ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr10:101,156,673...101,161,926
Ensembl chr10:100,657,708...100,663,479 		JBrowse link
G Atrx ATRX, chromatin remodeler disease_progression ISO RGD PMID:31374064 RGD:127285382 NCBI chr  X:74,916,548...75,062,880
Ensembl chr  X:70,850,981...70,997,330 		JBrowse link
G Axin2 axin 2 susceptibility
disease_progression		 ISO DNA:SNP:cds:p.P50S(human)
DNA:SNPs::1712 +19 G>A,148 C>T(human)		 RGD PMID:16820935 PMID:30346805 RGD:151356657, RGD:151356655 NCBI chr10:94,393,379...94,426,579
Ensembl chr10:93,899,245...93,926,231 		JBrowse link
G Azgp1 alpha-2-glycoprotein 1, zinc-binding ISO mRNA,protein:increased expression:lung RGD PMID:17724461 RGD:153350134 NCBI chr12:22,044,685...22,051,248
Ensembl chr12:16,931,024...16,939,091 		JBrowse link
G Bap1 BRCA1 associated deubiquitinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231345 NCBI chr16:6,453,126...6,461,952
Ensembl chr16:6,446,709...6,455,535 		JBrowse link
G Bhlhe41 basic helix-loop-helix family, member e41 ISO mRNA:decreased expression:lung (human) RGD PMID:18223678 RGD:151665316 NCBI chr 4:180,565,003...180,569,415
Ensembl chr 4:178,834,271...178,838,468 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 exacerbates ISO mRNA:increased expression:B cell (human) RGD PMID:33098370 RGD:153323293 NCBI chr 8:13,285,702...13,313,329
Ensembl chr 8:5,000,845...5,015,802 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 ameliorates
disease_progression		 ISO mRNA:increased expression:lung (human) RGD PMID:31964418 RGD:153344516 NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Lung adenocarcinoma
ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma		 CTD
ClinVar		 PMID:12068308 PMID:12198537 PMID:12447372 PMID:12460918 PMID:12460919 More... NCBI chr 4:69,329,772...69,476,931
Ensembl chr 4:68,384,649...68,510,463 		JBrowse link
G Btk Bruton tyrosine kinase exacerbates
susceptibility		 ISO mRNA:decreased expression:lung (human) RGD PMID:31803536 PMID:32351880 RGD:151347849, RGD:151347848 NCBI chr  X:102,016,070...102,055,448
Ensembl chr  X:97,722,802...97,761,853 		JBrowse link
G Bzw2 basic leucine zipper and W2 domains 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 6:52,828,069...52,888,599
Ensembl chr 6:52,827,661...52,888,628 		JBrowse link
G Cadm1 cell adhesion molecule 1 IEP DNA, mRNA:hypermethylation, decreased expression:promoter:liver RGD PMID:16814249 RGD:2289096 NCBI chr 8:56,744,374...57,075,264
Ensembl chr 8:47,847,325...48,182,833 		JBrowse link
G Calr calreticulin treatment ISO human cells and recombinant gene in a mouse model RGD PMID:18245558 RGD:150521698 NCBI chr19:40,213,367...40,218,262
Ensembl chr19:23,308,351...23,313,414 		JBrowse link
G Capg capping actin protein, gelsolin like ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr 4:106,152,912...106,170,010
Ensembl chr 4:104,594,753...104,611,856 		JBrowse link
G Cbx5 chromobox 5 disease_progression ISO mRNA,protein:increased expression:lung: RGD PMID:22900142 RGD:9586743 NCBI chr 7:136,203,827...136,254,575
Ensembl chr 7:134,331,335...134,375,022 		JBrowse link
G Cbx7 chromobox 7 ISO mRNA,DNA:decreased expression, loss of heterozygosity:lung: RGD PMID:22214847 RGD:9587356 NCBI chr 7:113,341,030...113,358,716
Ensembl chr 7:111,460,656...111,477,973 		JBrowse link
G Ccnd1 cyclin D1 disease_progression
treatment		 ISO RGD PMID:26681199 PMID:19355812 RGD:11536846, RGD:13434927 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccnd2 cyclin D2 disease_progression ISO RGD PMID:30308939 RGD:151665105 NCBI chr 4:161,653,048...161,675,422
Ensembl chr 4:159,962,363...159,989,495 		JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 2:84,302,621...84,313,773
Ensembl chr 2:82,590,630...82,602,930 		JBrowse link
G Cd163 CD163 molecule ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr 4:158,770,751...158,804,146
Ensembl chr 4:157,085,093...157,117,878 		JBrowse link
G Cd44 CD44 molecule disease_progression ISO mRNA:splice variants:lung
mRNA:increased expression:lung (human)		 RGD PMID:18091389 PMID:29537891 RGD:2289345, RGD:149735539 NCBI chr 3:109,610,824...109,699,776
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Cdc73 cell division cycle 73 exacerbates ISO mRNA:decreased expression:lung (human) RGD PMID:21692036 RGD:150537041 NCBI chr13:57,897,924...58,000,031
Ensembl chr13:55,357,226...55,449,656 		JBrowse link
G Cdh1 cadherin 1 IDA DNA:increased methylation RGD PMID:16329148 RGD:1599556 NCBI chr19:51,402,178...51,471,572
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Cdk12 cyclin-dependent kinase 12 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar NCBI chr10:83,697,174...83,793,676
Ensembl chr10:83,201,211...83,280,888
Ensembl chr10:83,201,211...83,280,888 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 ISO protein:increased expression:lung
ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma		 ClinVar
RGD		 PMID:5377176 PMID:7652577 PMID:8528263 PMID:8968104 PMID:9228064 More... RGD:13464277 NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:62,883,105...62,942,403 		JBrowse link
G Cdk6 cyclin-dependent kinase 6 ISO protein:increased expression:lung RGD PMID:10574260 RGD:13464325 NCBI chr 4:31,592,384...31,784,732
Ensembl chr 4:30,646,460...30,829,634 		JBrowse link
G Chd4 chromodomain helicase DNA binding protein 4 susceptibility
ameliorates		 ISO mRNA:increased expression:lung (human)
DNA:missense mutation:CDS:p.D140E (rs7479004) (human)
human cells in a mouse model		 RGD PMID:28486105 PMID:29667179 PMID:32228507 RGD:153323299, RGD:151660359, RGD:153323307 NCBI chr 4:159,584,623...159,617,867
Ensembl chr 4:157,899,391...157,931,541 		JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit susceptibility ISO mRNA,protein:decreased expression:lung
ClinVar Annotator: match by term: Lung adenocarcinoma
DNA:SNPs:multiples:multiples (human)
protein:increased expression:lung
DNA:SNP: :rs8042374(human)
associated with smoking; DNA:SNP: :rs1051730(human)		 ClinVar
RGD		 PMID:27993330 PMID:19223495 PMID:25233467 PMID:24686516 PMID:24686516 More... RGD:150524354, RGD:151347535, RGD:151347530, RGD:151347530, RGD:150527848 NCBI chr 8:64,297,755...64,311,251
Ensembl chr 8:55,401,702...55,415,165 		JBrowse link
G Chrna5 cholinergic receptor nicotinic alpha 5 subunit susceptibility
disease_progression		 ISO DNA:SNP:cds: p.D398N (rs1696996)(human)
ClinVar Annotator: match by term: Lung adenocarcinoma
mRNA:increased expression:lung
DNA:SNP: :rs503464(human)
associated with smoking; DNA:SNPs: :rs2036527, rs684513, rs667282(human)
DNA:SNP:cds: p.D398N(human)		 ClinVar
RGD		 PMID:27993330 PMID:19223495 PMID:20124469 PMID:23314339 PMID:20554942 More... RGD:150524354, RGD:150527851, RGD:150527849, RGD:150527848, RGD:150524359, RGD:150524356 NCBI chr 8:64,265,879...64,294,233
Ensembl chr 8:55,369,794...55,398,146 		JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit ISO mRNA:increased expression:lung
DNA:hypomethylation:promoter:		 RGD PMID:20124469 PMID:22945651 RGD:150527851, RGD:151361154 NCBI chr 8:64,312,644...64,333,319
Ensembl chr 8:55,418,313...55,437,027 		JBrowse link
G Clptm1l CLPTM1-like susceptibility
no_association
ameliorates		 ISO CTD Direct Evidence: marker/mechanism
DNA:SNP: :rs401681(human)
DNA:SNP::rs77518573(human)
DNA:SNP:: rs4975616(human)
DNA:SNP::rs401681(human)
DNA:SNP:: rs31490(human)
mRNA:increased expression:lung		 CTD
RGD		 PMID:22675468 PMID:24386361 PMID:31935503 PMID:19955392 PMID:24861918 More... RGD:150537098, RGD:150530635, RGD:150530502, RGD:150530499, RGD:150530498, RGD:150530485, RGD:150530483, RGD:150530483 NCBI chr 1:31,496,094...31,512,148
Ensembl chr 1:29,667,545...29,683,530 		JBrowse link
G Cmtr2 cap methyltransferase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr19:55,100,135...55,106,966
Ensembl chr19:38,190,642...38,197,804 		JBrowse link
G Col10a1 collagen type X alpha 1 chain disease_progression ISO mRNA:increased expression:lung RGD PMID:33324550 PMID:33324550 RGD:150429752, RGD:150429752 NCBI chr20:39,737,536...39,744,518
Ensembl chr20:38,182,494...38,189,494 		JBrowse link
G Crebbp CREB binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr10:11,842,307...11,968,266
Ensembl chr10:11,335,953...11,461,888 		JBrowse link
G Csf1r colony stimulating factor 1 receptor ISO protein:increased expression:lung (human) RGD PMID:23702648 RGD:150524280 NCBI chr18:56,834,152...56,860,804
Ensembl chr18:54,546,659...54,590,415 		JBrowse link
G Csrp3 cysteine and glycine rich protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:107,664,338...107,682,916
Ensembl chr 1:98,528,068...98,546,653 		JBrowse link
G Ctnnb1 catenin beta 1 ISO ClinVar Annotator: match by term: Lung adenocarcinoma
ClinVar Annotator: match by term: Adenocarcinoma of lung		 ClinVar PMID:10192393 PMID:25741868 PMID:26619011 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 exacerbates ISO protein:increased expression:lung (human)
mRNA:increased expression:lung (human)		 RGD PMID:30103827 PMID:19716197 RGD:152023735, RGD:152177480 NCBI chr13:42,630,383...42,634,288
Ensembl chr13:40,077,976...40,081,883 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 ISO protein:increased expression:lung (human) RGD PMID:19358281 RGD:152177688 NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 ameliorates ISO DNA:hypomethylation:promoter (human)
mRNA:decreased expression:lung (human)
human cell line in a mouse model		 RGD PMID:24736069 PMID:25519225 PMID:27793774 RGD:151361181, RGD:151665499, RGD:151665173 NCBI chr 3:179,694,647...179,709,083
Ensembl chr 3:159,275,947...159,290,383 		JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18669584 NCBI chr 1:91,359,278...91,372,554
Ensembl chr 1:82,231,611...82,244,887 		JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Lung adenocarcinoma		 CTD
ClinVar		 PMID:26206333 PMID:27993330 NCBI chr13:84,726,412...84,851,032
Ensembl chr13:82,195,463...82,317,363 		JBrowse link
G Dll4 delta like canonical Notch ligand 4 treatment IEP RGD PMID:33628824 RGD:155663482 NCBI chr 3:126,770,945...126,780,769
Ensembl chr 3:106,316,986...106,326,931 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:21067377 PMID:21518476 PMID:22160010 PMID:22722925 PMID:22744846 More... NCBI chr 6:32,507,316...32,621,678
Ensembl chr 6:26,822,609...26,896,687 		JBrowse link
G Dnmt3b DNA methyltransferase 3 beta susceptibility ISO DNA:SNPs,haplotype:promoter:-283T >C,-579G>T(human) RGD PMID:15528220 RGD:9589086 NCBI chr 3:162,590,777...162,629,313
Ensembl chr 3:142,130,592...142,169,124 		JBrowse link
G Dok1 docking protein 1 disease_progression ISO RGD PMID:20139980 RGD:152177521 NCBI chr 4:115,537,453...115,540,464
Ensembl chr 4:115,537,462...115,540,465 		JBrowse link
G Dok2 docking protein 2 disease_progression
exacerbates		 ISO mRNA:decreased expression:lung (human) RGD PMID:20139980 PMID:30475228 PMID:20139980 PMID:24255704 RGD:152177521, RGD:152177492, RGD:152177521, RGD:152177493 NCBI chr15:52,237,046...52,251,091
Ensembl chr15:45,827,398...45,841,402 		JBrowse link
G Dok3 docking protein 3 disease_progression ISO RGD PMID:20139980 RGD:152177521 NCBI chr17:9,109,633...9,115,188
Ensembl chr17:9,109,597...9,115,188 		JBrowse link
G Dot1l DOT1 like histone lysine methyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr 7:9,569,439...9,607,095
Ensembl chr 7:8,917,786...8,956,475 		JBrowse link
G E2f1 E2F transcription factor 1 ISO mRNA:increased expression:lung RGD PMID:26695082 RGD:13464334 NCBI chr 3:163,524,739...163,535,563
Ensembl chr 3:143,049,478...143,075,361 		JBrowse link
G E2f3 E2F transcription factor 3 ISO RGD PMID:16938365 RGD:13464341 NCBI chr17:34,810,355...34,887,725
Ensembl chr17:34,601,830...34,676,253 		JBrowse link
G Eef2 eukaryotic translation elongation factor 2 exacerbates ISO protein:increased expression:lung (human) RGD PMID:21554491 RGD:153298904 NCBI chr 7:9,183,836...9,196,255
Ensembl chr 7:8,533,116...8,559,183 		JBrowse link
G Eef2k eukaryotic elongation factor-2 kinase ameliorates ISO Human cells in mouse model RGD PMID:30522114 RGD:153298964 NCBI chr 1:184,824,420...184,888,048
Ensembl chr 1:175,393,154...175,455,164 		JBrowse link
G Egf epidermal growth factor ISO DNA:polymorphism: :p.A61G (human) RGD PMID:26625757 RGD:11538684 NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:218,219,415...218,302,064 		JBrowse link
G Egfr epidermal growth factor receptor disease_progression ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Adenocarcinoma of lung, somatic | ClinVar Annotator: match by term: Lung adenocarcinoma		 CTD
ClinVar
RGD		 PMID:11423618 PMID:15118073 PMID:15118125 PMID:15272417 PMID:15329413 More... RGD:126790475 NCBI chr14:95,378,626...95,551,358
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 disease_progression ISO RGD PMID:20940408 RGD:9589170 NCBI chr20:3,924,263...3,941,238
Ensembl chr20:3,919,624...3,941,547 		JBrowse link
G Eif2b1 eukaryotic translation initiation factor 2B subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr12:37,686,149...37,694,830
Ensembl chr12:32,025,557...32,046,601 		JBrowse link
G Eif2b4 eukaryotic translation initiation factor 2B subunit delta ISO CTD Direct Evidence: marker/mechanism CTD PMID:24366584 NCBI chr 6:30,903,148...30,908,803
Ensembl chr 6:25,183,186...25,188,829 		JBrowse link
G Eif2b5 eukaryotic translation initiation factor 2B subunit epsilon ISO CTD Direct Evidence: marker/mechanism CTD PMID:24366584 NCBI chr11:80,394,433...80,404,468
Ensembl chr11:80,394,433...80,404,419 		JBrowse link
G Eif3e eukaryotic translation initiation factor 3 subunit E ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 7:76,224,567...76,257,346
Ensembl chr 7:74,339,828...74,373,096 		JBrowse link
G Eml4 EMAP like 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22980554 PMID:22999080 NCBI chr 6:16,972,054...17,087,365
Ensembl chr 6:11,219,566...11,334,879 		JBrowse link
G Emx2 empty spiracles homeobox 2 exacerbates ISO mRNA,protein:decreased expression:lung (human) RGD PMID:21726823 RGD:153323303 NCBI chr 1:258,626,584...258,633,594
Ensembl chr 1:258,626,584...258,633,594 		JBrowse link
G Eno1 enolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 PMID:27602772 NCBI chr 5:166,002,867...166,014,252
Ensembl chr 5:160,719,951...160,731,336
Ensembl chr 3:160,719,951...160,731,336 		JBrowse link
G Ep300 E1A binding protein p300 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 disease_progression ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar
RGD		 PMID:15457249 PMID:15753357 PMID:16638863 PMID:18334834 PMID:22325357 More... RGD:126790475 NCBI chr10:83,907,491...83,931,365
Ensembl chr10:83,411,313...83,435,078 		JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 disease_progression ISO RGD PMID:26824984 RGD:126790475 NCBI chr 7:1,579,079...1,600,379
Ensembl chr 7:996,225...1,015,525 		JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 disease_progression ISO RGD PMID:26824984 RGD:126790475 NCBI chr 9:76,973,386...78,045,633
Ensembl chr 9:69,531,481...70,596,595 		JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:21327329 NCBI chr 1:88,099,308...88,135,966
Ensembl chr 1:78,996,390...79,007,963 		JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor ISO mRNA, protein:increased expression:lung (human) RGD PMID:31615563 RGD:155260344 NCBI chr16:7,771,311...7,841,895
Ensembl chr16:7,765,013...7,835,587 		JBrowse link
G Ercc6l ERCC excision repair 6 like, spindle assembly checkpoint helicase exacerbates ISO mRNA:increased expression:lung (human) RGD PMID:35150321 RGD:155260359 NCBI chr  X:71,285,380...71,301,186
Ensembl chr  X:67,245,414...67,280,756 		JBrowse link
G Ergic3 ERGIC and golgi 3 ameliorates
disease_progression		 ISO mRNA,protein:increased expression:lung (human) RGD PMID:27588471 PMID:23374247 RGD:153323314, RGD:151708716 NCBI chr 3:164,985,108...164,994,897
Ensembl chr 3:144,525,092...144,534,813 		JBrowse link
G Erp29 endoplasmic reticulum protein 29 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr12:40,750,177...40,756,607
Ensembl chr12:35,089,707...35,096,376 		JBrowse link
G Esco2 establishment of sister chromatid cohesion N-acetyltransferase 2 ameliorates ISO RGD PMID:33573689 RGD:155791670 NCBI chr15:44,210,124...44,230,785
Ensembl chr15:40,034,568...40,055,306
Ensembl chr15:40,034,568...40,055,306 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit disease_progression ISO RGD PMID:24097870 RGD:126781716 NCBI chr 4:77,624,223...77,698,598
Ensembl chr 4:76,624,399...76,687,362 		JBrowse link
G Fas Fas cell surface death receptor ISO mRNA:decreased expression:lung (human) RGD PMID:29254206 RGD:151665107 NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Fasn fatty acid synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G Fbl fibrillarin ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:92,597,407...92,606,507
Ensembl chr 1:83,469,832...83,478,932 		JBrowse link
G Fes FES proto-oncogene, tyrosine kinase treatment ISO human cells in a mouse model RGD PMID:31573955 RGD:153323295 NCBI chr 1:143,746,945...143,756,181
Ensembl chr 1:134,337,698...134,346,934 		JBrowse link
G Fgf10 fibroblast growth factor 10 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr 2:52,533,939...52,610,980
Ensembl chr 2:50,800,992...50,876,866 		JBrowse link
G Fgf18 fibroblast growth factor 18 ISO mRNA:decreased expression:lung (human) RGD PMID:19296538 RGD:150429981 NCBI chr10:18,210,240...18,241,929
Ensembl chr10:17,706,174...17,736,818 		JBrowse link
G Fgf9 fibroblast growth factor 9 disease_progression ISO protein:increased expression:lung (human)
mRNA:decreased expression:lung (human)		 RGD PMID:19296538 PMID:19358281 PMID:20464547 RGD:150429981 RGD:152177688, RGD:152975620 NCBI chr15:36,325,552...36,369,995
Ensembl chr15:32,210,074...32,253,309 		JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 disease_progression
exacerbates		 ISO DNA:SNP:exon 9: p.G288R (human)
DNA:SNP:exon 9: p.G388R (rs351855)(human)
human cells in mouse model		 RGD PMID:16061909 PMID:19296538 PMID:29402970 RGD:150429976, RGD:150429981, RGD:150429984 NCBI chr17:9,466,686...9,481,423
Ensembl chr17:9,461,547...9,476,242 		JBrowse link
G Fkbp11 FKBP prolyl isomerase 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 7:131,750,828...131,757,784
Ensembl chr 7:129,871,870...129,875,303 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr12:12,333,050...12,504,750
Ensembl chr12:7,297,292...7,468,626 		JBrowse link
G Foxa1 forkhead box A1 ISO mRNA:increased expression:lung
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:34254728 PMID:12234996 PMID:29072684 RGD:151665758, RGD:151665822 NCBI chr 6:80,838,380...80,871,195
Ensembl chr 6:75,103,503...75,136,188 		JBrowse link
G Foxo3 forkhead box O3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19380174 NCBI chr20:47,251,968...47,348,254
Ensembl chr20:45,672,995...45,764,561 		JBrowse link
G Foxp1 forkhead box P1 IEP mRNA:decreased expression:lung (rat) RGD PMID:16023287 RGD:11561933 NCBI chr 4:133,117,346...133,808,647
Ensembl chr 4:131,564,756...132,112,258 		JBrowse link
G Foxp2 forkhead box P2 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr 4:44,099,848...44,677,700
Ensembl chr 4:43,133,912...43,711,683 		JBrowse link
G Foxp4 forkhead box P4 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr 9:13,058,506...13,115,406
Ensembl chr 9:13,058,476...13,114,879 		JBrowse link
G Fpr2 formyl peptide receptor 2 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr 1:67,449,637...67,458,272
Ensembl chr 1:58,776,752...58,786,019 		JBrowse link
G Frzb frizzled-related protein severity ISO mRNA:decreased expression:lung (human) RGD PMID:27623992 RGD:32716395 NCBI chr 3:85,739,162...85,772,168
Ensembl chr 3:65,332,277...65,365,208 		JBrowse link
G Fubp1 far upstream element binding protein 1 ISO mRNA:decreased expression:lung (human) RGD PMID:32481602 RGD:151361197 NCBI chr 2:243,819,529...243,846,544
Ensembl chr 2:241,159,512...241,186,602 		JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 4:159,648,592...159,653,436
Ensembl chr 4:157,962,343...157,966,235 		JBrowse link
G Gar1 GAR1 ribonucleoprotein ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 2:221,049,471...221,056,749
Ensembl chr 2:218,375,353...218,382,524 		JBrowse link
G Gart phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr11:44,351,841...44,377,086
Ensembl chr11:30,865,889...30,891,125 		JBrowse link
G Gjb2 gap junction protein, beta 2 IDA DNA, mRNA:hypermethylation, decreased expression:lung RGD PMID:16637067 RGD:11568669 NCBI chr15:35,375,977...35,393,817
Ensembl chr15:31,260,357...31,278,177 		JBrowse link
G Gng11 G protein subunit gamma 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24366584 NCBI chr 4:32,023,003...32,028,443
Ensembl chr 4:32,023,003...32,028,442 		JBrowse link
G Gnpnat1 glucosamine-phosphate N-acetyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr15:18,596,180...18,608,854
Ensembl chr15:18,596,442...18,608,739 		JBrowse link
G Golm1 golgi membrane protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr17:4,996,978...5,049,278
Ensembl chr17:4,996,104...5,034,057 		JBrowse link
G Gpi glucose-6-phosphate isomerase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:95,965,389...95,996,932
Ensembl chr 1:86,828,216...86,856,086 		JBrowse link
G Gpx3 glutathione peroxidase 3 ISO mRNA:decreased expression:lung (human) RGD PMID:23374247 RGD:151708716 NCBI chr10:39,529,335...39,537,406
Ensembl chr10:39,028,570...39,037,035 		JBrowse link
G Grwd1 glutamate-rich WD repeat containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:105,437,708...105,443,410
Ensembl chr 1:96,301,261...96,307,201 		JBrowse link
G H1f10 H1.10 linker histone ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 4:120,440,515...120,441,578
Ensembl chr 4:120,440,870...120,441,448 		JBrowse link
G Hells helicase, lymphoid specific ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:246,113,580...246,159,230
Ensembl chr 1:236,701,758...236,746,844 		JBrowse link
G Hk1 hexokinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr20:30,773,222...30,874,814
Ensembl chr20:30,230,486...30,332,131 		JBrowse link
G Hk2 hexokinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 4:116,792,258...116,841,275
Ensembl chr 4:115,234,509...115,283,530 		JBrowse link
G Hmgb2 high mobility group box 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24366584 PMID:27602772 NCBI chr16:37,721,374...37,723,950
Ensembl chr16:32,710,658...32,713,140
Ensembl chr 1:32,710,658...32,713,140 		JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 7:136,253,633...136,260,085
Ensembl chr 7:134,375,150...134,381,609 		JBrowse link
G Hoxb7 homeo box B7 severity ISO protein:increased expression:lung epithelium (human) RGD PMID:22911672 RGD:10402176 NCBI chr10:81,749,159...81,752,577
Ensembl chr10:81,252,553...81,256,034 		JBrowse link
G Hras HRas proto-oncogene, GTPase ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma		 CTD
ClinVar		 PMID:1904555 PMID:3510078 PMID:11150980 PMID:12835555 PMID:16155195 More... NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:196,296,263...196,300,615 		JBrowse link
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr  X:24,568,551...24,571,012
Ensembl chr  X:21,089,122...21,109,488 		JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 ISO mRNA:increased expression:lung (human) RGD PMID:23374247 RGD:151708716 NCBI chr 7:22,997,962...23,012,293
Ensembl chr 7:21,110,457...21,124,788 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr12:26,430,640...26,432,301
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Htr4 5-hydroxytryptamine receptor 4 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr18:58,036,277...58,221,327
Ensembl chr18:55,766,725...55,949,321 		JBrowse link
G Htra1 HtrA serine peptidase 1 disease_progression ISO human cells in mouse model RGD PMID:24356998 RGD:152975621 NCBI chr 1:194,928,069...194,977,619
Ensembl chr 1:185,497,735...185,547,379 		JBrowse link
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 disease_progression ISO mRNA:increased expression:lung (human)
ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma
protein:increased expression:blood plasma (human)		 ClinVar
RGD		 PMID:18772396 PMID:19657110 PMID:19798509 PMID:19818334 PMID:20946881 More... RGD:149735539, RGD:149735540 NCBI chr 9:74,027,887...74,057,442
Ensembl chr 9:66,534,146...66,563,708 		JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 severity ISO protein:increased expression:lung (human)
protein:increased expression:blood serum (human)		 RGD PMID:30128035 PMID:29465809 RGD:149735564, RGD:149735567 NCBI chr 1:143,447,925...143,467,248
Ensembl chr 1:134,029,772...134,058,025 		JBrowse link
G Igf2r insulin-like growth factor 2 receptor IAGP mRNA:deletions: :c.3698_4902del, c.3366_4902del, c.3817_4697del (rat) RGD PMID:12503077 RGD:1298968 NCBI chr 1:50,526,878...50,615,265
Ensembl chr 1:47,979,109...48,067,501 		JBrowse link
G Ikzf1 IKAROS family zinc finger 1 exacerbates
ameliorates		 ISO protein:increased expression:lung (human)
mRNA:increased expression:lung (human)		 RGD PMID:33738286 PMID:32787735 RGD:151347632, RGD:150540324 NCBI chr14:90,468,696...90,556,522
Ensembl chr14:86,255,065...86,342,416 		JBrowse link
G Il1r2 interleukin 1 receptor type 2 disease_progression
severity		 ISO mRNA:altered expression:lung (human)
mRNA:increased expression:lung (human)		 RGD PMID:31921619 PMID:29942094 RGD:152998982, RGD:152998998 NCBI chr 9:49,879,928...49,920,374
Ensembl chr 9:42,384,433...42,424,725 		JBrowse link
G Impdh2 inosine monophosphate dehydrogenase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 8:118,135,204...118,139,892
Ensembl chr 8:109,256,728...109,261,359 		JBrowse link
G Ipo4 importin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr15:33,087,321...33,097,241
Ensembl chr15:29,117,365...29,127,285 		JBrowse link
G Ipo5 importin 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr15:104,397,626...104,447,985
Ensembl chr15:98,005,299...98,041,126 		JBrowse link
G Iqsec1 IQ motif and Sec7 domain ArfGEF 1 disease_progression ISO RGD PMID:24902879 RGD:153350085 NCBI chr 4:124,725,917...125,045,351
Ensembl chr 4:123,168,719...123,488,172 		JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 ISO mRNA:increased expression:lung (human) RGD PMID:21278795 RGD:36049796 NCBI chr 7:57,538,522...57,600,166
Ensembl chr 7:55,653,962...55,713,121 		JBrowse link
G Ireb2 iron responsive element binding protein 2 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr 8:64,124,152...64,207,702
Ensembl chr 8:55,228,085...55,311,611 		JBrowse link
G Jak2 Janus kinase 2 treatment ISO human cells in mouse model RGD PMID:27025877 RGD:11574134 NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:24366584 NCBI chr19:40,081,126...40,082,910
Ensembl chr19:23,176,294...23,178,035 		JBrowse link
G Kcnj4 potassium inwardly-rectifying channel, subfamily J, member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30512237 NCBI chr 7:112,927,494...112,954,547
Ensembl chr 7:111,047,094...111,074,151 		JBrowse link
G Klf5 KLF transcription factor 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr15:82,472,081...82,487,267
Ensembl chr15:76,064,258...76,079,445 		JBrowse link
G Kmt2c lysine methyltransferase 2C disease_progression
onset		 ISO RGD PMID:32867667 PMID:30821106 RGD:151356760, RGD:151356761 NCBI chr 4:10,353,698...10,755,965
Ensembl chr 4:9,609,627...9,833,539 		JBrowse link
G Kpna2 karyopherin subunit alpha 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr10:92,433,678...92,445,841
Ensembl chr10:91,933,951...91,946,150 		JBrowse link
G Kras KRAS proto-oncogene, GTPase ISO DNA:point mutation:CDS:p.G12C (human)
ClinVar Annotator: match by term: Lung adenocarcinoma
ClinVar Annotator: match by term: Adenocarcinoma of lung
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
RGD		 PMID:2278970 PMID:3122217 PMID:6320174 PMID:8143615 PMID:8425762 More... RGD:1600465 NCBI chr 4:179,916,255...179,949,613 JBrowse link
G Ldha lactate dehydrogenase A ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:106,508,092...106,517,512
Ensembl chr 1:97,366,021...97,433,472 		JBrowse link
G Lect2 leukocyte cell-derived chemotaxin 2 ameliorates ISO human cells in mouse model RGD PMID:30453282 RGD:153323337 NCBI chr17:8,050,034...8,056,256
Ensembl chr17:8,044,759...8,050,983 		JBrowse link
G Lmna lamin A/C ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr 2:176,237,564...176,265,301
Ensembl chr 2:173,939,751...173,960,423 		JBrowse link
G Lmnb1 lamin B1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr18:52,373,939...52,413,284
Ensembl chr18:50,175,874...50,214,502 		JBrowse link
G Lrp1b LDL receptor related protein 1B disease_progression ISO DNA:mutations:multiple: (human) RGD PMID:18948947 RGD:11064706 NCBI chr 3:45,004,001...47,125,147
Ensembl chr 3:24,594,991...26,715,505 		JBrowse link
G Lrrc56 leucine rich repeat containing 56 ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:1904555 PMID:3510078 PMID:11150980 PMID:12835555 PMID:16155195 More... NCBI chr 1:205,729,402...205,744,754
Ensembl chr 1:196,299,846...196,315,172 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:lung (human)		 CTD
RGD		 PMID:22135231 PMID:29254206 RGD:151665107 NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:64,683,449...64,755,147 		JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 severity ISO RGD PMID:21896780 PMID:12231543 RGD:150429783, RGD:150429821 NCBI chr10:50,842,348...50,947,063
Ensembl chr10:50,344,915...50,447,993 		JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 exacerbates ISO human gene in a mouse model RGD PMID:34236045 RGD:155230828 NCBI chr12:7,389,032...7,398,377
Ensembl chr12:2,591,219...2,604,222 		JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 exacerbates ISO RGD PMID:23533274 RGD:151356978 NCBI chr17:58,078,175...58,098,455
Ensembl chr17:53,383,131...53,403,216 		JBrowse link
G Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 ameliorates
exacerbates		 ISO human cell line in a mouse model
mRNA, protein:increased expression:lung (human)		 RGD PMID:22824148 PMID:28306189 PMID:33510968 RGD:151347677, RGD:151347678, RGD:151347681 NCBI chr 9:49,696,573...49,822,353
Ensembl chr 9:42,200,278...42,326,698 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 exacerbates ISO mRNA:increased expression:lung (human) RGD PMID:31969449 RGD:151665505 NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,749,670...6,810,589 		JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member severity
treatment		 ISO mRNA:increased expression:lung (human)
human cells in mouse model		 RGD PMID:31200834 PMID:31200834 RGD:151356911, RGD:151356911 NCBI chr 2:185,884,840...185,912,532
Ensembl chr 2:183,219,220...183,222,303 		JBrowse link
G Meox1 mesenchyme homeobox 1 ISO CTD Direct Evidence: therapeutic CTD PMID:34837450 NCBI chr10:87,318,668...87,338,169
Ensembl chr10:86,818,478...86,837,660 		JBrowse link
G Mier3 MIER family member 3 ameliorates ISO RGD PMID:35117188 RGD:407571696 NCBI chr 2:45,021,167...45,049,745
Ensembl chr 2:43,287,916...43,316,136 		JBrowse link
G Mir127 microRNA 127 treatment ISO Human cells in mouse model RGD PMID:27869168 RGD:152995353 NCBI chr 6:134,328,454...134,328,550
Ensembl chr 6:128,546,215...128,546,311 		JBrowse link
G Mir154 microRNA 154 ISO associated with nicotine dependence; RNA:decreased expression:blood serum (human) RGD PMID:25386559 RGD:152995475 NCBI chr 6:134,574,352...134,574,435
Ensembl chr 6:128,752,947...128,753,030 		JBrowse link
G Mir20a microRNA 20a ISO RGD PMID:26560875 RGD:11572141 NCBI chr15:98,588,303...98,588,387
Ensembl chr15:92,181,084...92,181,168 		JBrowse link
G Mir21 microRNA 21 disease_progression ISO RNA:increased expression:lung (human)
miRNA:increased expression:sputum (human)		 RGD PMID:29892003 PMID:27777637 RGD:152998892, RGD:152998954 NCBI chr10:71,902,600...71,902,691
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mir31 microRNA 31 severity
disease_progression		 ISO RNA:increased expression:lung (human) RGD PMID:26657862 PMID:29367106 PMID:23946296 PMID:27215092 RGD:11343268, RGD:152998945, RGD:152998944, RGD:11250998 NCBI chr 5:108,714,849...108,714,954 JBrowse link
G Mki67 marker of proliferation Ki-67 disease_progression ISO protein:altered expression:lung (human) RGD PMID:26942465 RGD:152999419 NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:190,496,319...190,522,762 		JBrowse link
G Mlh1 mutL homolog 1 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr 8:120,074,871...120,112,109
Ensembl chr 8:111,196,468...111,233,617 		JBrowse link
G Mre11 MRE11 homolog, double strand break repair nuclease ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 8:19,900,211...19,961,906
Ensembl chr 8:11,632,354...11,678,279 		JBrowse link
G Mrpl12 mitochondrial ribosomal protein L12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr10:106,256,746...106,261,249
Ensembl chr10:105,758,410...105,762,913 		JBrowse link
G Mrps5 mitochondrial ribosomal protein S5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 3:135,274,333...135,290,577
Ensembl chr 3:114,821,046...114,837,291 		JBrowse link
G Ms4a1 membrane spanning 4-domains A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22514692 NCBI chr 1:217,331,274...217,351,934
Ensembl chr 1:207,906,374...207,918,512 		JBrowse link
G Msh2 mutS homolog 2 no_association ISO DNA:polymorphisms:introns:IVS10+12A>G, IVS12-6T>C (human)
DNA:polymorphisms:promoter, intron:-118T>C, IVS1+9G>C (human)		 RGD PMID:16614121 PMID:16614121 RGD:11065547, RGD:11065547 NCBI chr 6:12,567,368...12,626,534
Ensembl chr 6:6,813,795...6,872,938 		JBrowse link
G Msh3 mutS homolog 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21327329 NCBI chr 2:25,179,400...25,320,857 JBrowse link
G Msh6 mutS homolog 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21327329 NCBI chr 6:12,316,190...12,333,505
Ensembl chr 6:6,562,632...6,579,956 		JBrowse link
G Muc1 mucin 1, cell surface associated ISO mRNA:increased expression:lung RGD PMID:8694545 RGD:5131260 NCBI chr 2:176,933,312...176,938,497
Ensembl chr 2:174,635,995...174,640,733 		JBrowse link
G Muc4 mucin 4, cell surface associated disease_progression ISO protein:increased expression:trachea RGD PMID:17126950 RGD:5131208 NCBI chr11:81,513,321...81,575,200 JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr 1:206,293,717...206,326,006
Ensembl chr 1:196,864,336...196,896,475 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor ISO human cell line in mouse model
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:26656844 PMID:27602772 PMID:20033209 RGD:7207787 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor treatment
ameliorates		 ISO mouse cell line in a mouse model RGD PMID:32140881 PMID:30712876 RGD:150520172, RGD:150540309 NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Naa10 N(alpha)-acetyltransferase 10, NatA catalytic subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr  X:156,807,378...156,812,632
Ensembl chr  X:151,656,056...151,661,252 		JBrowse link
G Naip6 NLR family, apoptosis inhibitory protein 6 ameliorates ISO mRNA:increased expression:lung (human) RGD PMID:31964418 RGD:153344516 NCBI chr 2:33,241,520...33,293,184
Ensembl chr 2:31,507,424...31,570,542 		JBrowse link
G Ncapg non-SMC condensin I complex, subunit G ISO CTD Direct Evidence: marker/mechanism CTD PMID:34419073 NCBI chr14:69,616,473...69,645,445
Ensembl chr14:65,404,163...65,432,902 		JBrowse link
G Ncl nucleolin ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 9:94,447,559...94,456,083
Ensembl chr 9:86,998,019...87,008,136 		JBrowse link
G Nkx2-1 NK2 homeobox 1 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr 6:79,731,677...79,735,952
Ensembl chr 6:73,996,601...73,999,791 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
G Nop56 NOP56 ribonucleoprotein ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 3:137,926,187...137,934,971
Ensembl chr 3:117,477,053...117,481,841 		JBrowse link
G Nop58 NOP58 ribonucleoprotein ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 9:68,614,992...68,638,911
Ensembl chr 9:61,120,929...61,144,810 		JBrowse link
G Notch1 notch receptor 1 treatment IEP RGD PMID:33628824 RGD:155663482 NCBI chr 3:29,676,040...29,721,613
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Npm1 nucleophosmin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr10:18,245,739...18,255,913
Ensembl chr10:17,739,941...17,751,645
Ensembl chr  X:17,739,941...17,751,645 		JBrowse link
G Npm3 nucleophosmin/nucleoplasmin, 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:244,595,638...244,597,623
Ensembl chr 1:244,595,644...244,597,591 		JBrowse link
G Nudt21 nudix hydrolase 21 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr19:10,980,797...10,996,903
Ensembl chr19:10,974,241...10,991,682 		JBrowse link
G Nuf2 NUF2 component of NDC80 kinetochore complex disease_progression ISO RGD PMID:32226507 RGD:28912743 NCBI chr13:84,226,448...84,290,957
Ensembl chr13:81,693,598...81,722,766 		JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23951099 NCBI chr 4:148,030,237...148,037,599
Ensembl chr 4:146,474,750...146,484,766 		JBrowse link
G Pabpc4 poly(A) binding protein, cytoplasmic 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 5:140,847,835...140,864,089
Ensembl chr 5:135,563,562...135,578,979 		JBrowse link
G Pacrg parkin coregulated ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:12719539 NCBI chr 1:52,430,390...52,853,272
Ensembl chr 1:49,882,630...50,305,430 		JBrowse link
G Pcbd1 pterin-4 alpha-carbinolamine dehydratase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr20:29,573,362...29,587,181
Ensembl chr20:28,953,864...29,044,292
Ensembl chr20:28,953,864...29,044,292 		JBrowse link
G Pign phosphatidylinositol glycan anchor biosynthesis, class N ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr13:21,659,092...21,812,932
Ensembl chr13:21,662,455...21,806,790 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma		 CTD
ClinVar		 PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 More... NCBI chr 2:117,103,643...117,177,411
Ensembl chr 2:115,174,984...115,249,032 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 ISO mRNA:decreased expression:lung RGD PMID:26695082 RGD:13464334 NCBI chr 2:34,612,946...34,697,660
Ensembl chr 2:32,882,032...32,963,631 		JBrowse link
G Pitx2 paired-like homeodomain 2 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr 2:220,391,417...220,411,588
Ensembl chr 2:217,717,693...217,737,293 		JBrowse link
G Plcg1 phospholipase C, gamma 1 exacerbates ISO protein:decreased expression:lung (human) RGD PMID:33077911 RGD:151356960 NCBI chr 3:169,805,299...169,836,040
Ensembl chr 3:149,385,587...149,416,330 		JBrowse link
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 disease_progression ISO RGD PMID:29072684 RGD:151665822 NCBI chr 8:101,964,318...102,047,022
Ensembl chr 8:93,084,513...93,167,255 		JBrowse link
G Pold1 DNA polymerase delta 1, catalytic subunit exacerbates ISO protein:increased expression:lung (human) RGD PMID:33442399 RGD:153323317 NCBI chr 1:104,161,984...104,178,074
Ensembl chr 1:95,025,499...95,036,465 		JBrowse link
G Polr1d RNA polymerase I and III subunit D ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr12:13,084,505...13,118,069
Ensembl chr12:7,970,595...8,005,624 		JBrowse link
G Ppan peter pan homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 8:27,700,147...27,704,127
Ensembl chr 8:19,423,961...19,427,938 		JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr 2:227,839,058...228,113,560
Ensembl chr 2:225,165,766...225,438,974 		JBrowse link
G Pramex1 PRAME like, X-linked 1 ISO mRNA:decreased expression:lung (human) RGD PMID:27241212 RGD:11535020 NCBI chr  X:102,862,457...102,867,725
Ensembl chr  X:98,569,415...98,572,096 		JBrowse link
G Prdm1 PR/SET domain 1 exacerbates ISO RGD PMID:28378641 RGD:150530469 NCBI chr20:49,542,465...49,564,088
Ensembl chr20:47,959,858...47,981,488 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:10072423 PMID:12719539 PMID:20301651 PMID:22956510 PMID:25741868 More... NCBI chr 1:51,236,410...52,430,242
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Psat1 phosphoserine aminotransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:222,623,553...222,646,187
Ensembl chr 1:213,196,709...213,218,682 		JBrowse link
G Ptch1 patched 1 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar
RGD		 PMID:27993330 PMID:28492532 PMID:33359005 RGD:150524339 NCBI chr17:1,548,449...1,613,461
Ensembl chr17:1,542,877...1,607,333 		JBrowse link
G Pten phosphatase and tensin homolog ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Ptpn13 protein tyrosine phosphatase, non-receptor type 13 exacerbates
susceptibility		 ISO mRNA,protein:decreased expression:lung
DNA:missense mutations:cds:p.I1522M, p.Y2081D (human)		 RGD PMID:22245727 PMID:33536603 PMID:19672627 RGD:152176663, RGD:152975626, RGD:152176665 NCBI chr14:6,412,841...6,587,238
Ensembl chr14:6,108,211...6,282,563 		JBrowse link
G Ptprb protein tyrosine phosphatase, receptor type, B disease_progression ISO mRNA:altered expression:lung (human)
mRNA:decreased expression:lung (human)		 RGD PMID:29254206 PMID:7981622 RGD:151665107, RGD:151665112 NCBI chr 7:53,816,197...53,920,760
Ensembl chr 7:51,930,015...52,034,748 		JBrowse link
G Ptprj protein tyrosine phosphatase, receptor type, J susceptibility ISO DNA:missense mutations:cds:p.R326Q, p.Q276P (human) RGD PMID:19672627 RGD:152176665 NCBI chr 3:96,861,785...97,017,702
Ensembl chr 3:76,405,927...76,562,260 		JBrowse link
G Rac1 Rac family small GTPase 1 exacerbates
ameliorates		 ISO mRNA:increased expression:lung (human) RGD PMID:31779616 PMID:32366477 RGD:152998910, RGD:153345550 NCBI chr12:16,150,411...16,170,864
Ensembl chr12:11,036,698...11,057,251 		JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:1760348 PMID:8601312 PMID:10064593 PMID:12077328 PMID:17603482 More... NCBI chr 4:150,352,158...150,412,813
Ensembl chr 4:148,679,530...148,740,317 		JBrowse link
G Rangrf RAN guanine nucleotide release factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr10:54,176,325...54,177,696
Ensembl chr10:53,677,467...53,678,840 		JBrowse link
G Rarb retinoic acid receptor, beta ISO DNA:hypomethylation:lung RGD PMID:26695082 RGD:13464334 NCBI chr15:10,837,252...11,482,037
Ensembl chr15:8,406,492...9,051,288 		JBrowse link
G Rasa1 RAS p21 protein activator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr 2:17,593,136...17,676,707
Ensembl chr 2:15,857,980...15,940,854 		JBrowse link
G Rb1 RB transcriptional corepressor 1 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr15:54,780,858...54,911,989
Ensembl chr15:48,371,296...48,502,302 		JBrowse link
G Rbm10 RNA binding motif protein 10 ISO mRNA, protein:decreased expression:lung
DNA:missense mutations, protein-truncating variants: :multiple		 RGD PMID:29085465 PMID:22980975 PMID:30955253 RGD:151356983, RGD:11097386, RGD:151356984 NCBI chr  X:4,093,914...4,126,060
Ensembl chr  X:1,540,398...1,572,575 		JBrowse link
G Rcl1 RNA terminal phosphate cyclase-like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:236,238,078...236,282,597
Ensembl chr 1:226,824,534...226,902,315 		JBrowse link
G Rfc4 replication factor C subunit 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr11:91,254,273...91,268,727
Ensembl chr11:77,749,638...77,764,122 		JBrowse link
G Rin3 Ras and Rab interactor 3 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr 6:127,196,648...127,305,821
Ensembl chr 6:121,431,339...121,540,957 		JBrowse link
G Rnaseh2a ribonuclease H2, subunit A ISO CTD Direct Evidence: marker/mechanism CTD PMID:34254728 NCBI chr19:23,186,325...23,196,045
Ensembl chr19:23,186,383...23,196,041 		JBrowse link
G Rnf43 ring finger protein 43 severity ISO human cells in a mouse model RGD PMID:31286874 RGD:151361222 NCBI chr10:72,958,744...73,034,540
Ensembl chr10:72,464,348...72,536,977 		JBrowse link
G Ros1 ROS proto-oncogene 1 , receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Lung adenocarcinoma		 CTD
ClinVar		 PMID:22215748 PMID:27993330 NCBI chr20:31,975,328...32,126,675
Ensembl chr20:31,432,637...31,583,865 		JBrowse link
G Rpl10a ribosomal protein L10A ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr20:6,388,800...6,391,358
Ensembl chr20:6,385,823...6,391,357
Ensembl chr 9:6,385,823...6,391,357 		JBrowse link
G Rpl13a ribosomal protein L13A ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:104,746,223...104,748,975
Ensembl chr 1:95,609,370...95,620,463 		JBrowse link
G Rpl27a ribosomal protein L27A ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:163,539,732...163,542,771 JBrowse link
G Rpl36a ribosomal protein L36A ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr  X:97,766,179...97,768,892
Ensembl chr  X:97,766,179...97,768,892
Ensembl chr20:97,766,179...97,768,892 		JBrowse link
G Rpsa ribosomal protein SA ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 8:128,728,761...128,732,736
Ensembl chr 8:119,851,225...119,855,247 		JBrowse link
G Rrm1 ribonucleotide reductase catalytic subunit M1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:166,235,904...166,260,206
Ensembl chr 1:156,823,960...156,848,261 		JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 6:47,044,755...47,075,370
Ensembl chr 6:41,340,557...41,346,773 		JBrowse link
G Rrs1 ribosome biogenesis regulator 1 homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 5:14,516,303...14,517,936
Ensembl chr 5:9,733,091...9,735,140 		JBrowse link
G Runx1 RUNX family transcription factor 1 ISO RGD PMID:28926105 RGD:126779571 NCBI chr11:45,325,778...45,560,300
Ensembl chr11:31,843,764...32,074,542 		JBrowse link
G Satb1 SATB homeobox 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 9:4,677,817...4,773,061
Ensembl chr 9:4,680,920...4,753,251 		JBrowse link
G Sdc1 syndecan 1 ISO mRNA:increased expression:lung (human) RGD PMID:23374247 RGD:151708716 NCBI chr 6:37,282,041...37,304,503
Ensembl chr 6:31,562,739...31,585,264 		JBrowse link
G Serpina3n serpin family A member 3N ISO protein:increased expression:cytoplasm RGD PMID:8620411 RGD:5147446 NCBI chr 6:129,088,392...129,095,950
Ensembl chr 6:123,323,629...123,332,433 		JBrowse link
G Setd2 SET domain containing 2, histone lysine methyltransferase ameliorates
exacerbates
severity		 ISO human cells and genes in mouse model
DNA:mutations:multiple (human)		 RGD PMID:33223508 PMID:27687306 PMID:33707235 PMID:28202515 RGD:150429633, RGD:150429649, RGD:150429648, RGD:126848875 NCBI chr 8:119,390,207...119,475,863
Ensembl chr 8:110,511,772...110,597,489 		JBrowse link
G Sfn stratifin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr 5:151,110,582...151,111,854
Ensembl chr 5:145,826,201...145,831,314 		JBrowse link
G Sftpc surfactant protein C ISO CTD Direct Evidence: marker/mechanism CTD PMID:25851810 NCBI chr15:52,006,274...52,009,324
Ensembl chr15:45,596,574...45,610,777 		JBrowse link
G Sfxn1 sideroflexin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr17:10,486,250...10,522,640
Ensembl chr17:10,486,271...10,522,529 		JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr10:45,968,959...45,990,341
Ensembl chr10:45,468,700...45,497,820 		JBrowse link
G Slc15a2 solute carrier family 15 member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr11:77,519,565...77,548,609
Ensembl chr11:64,014,182...64,043,225 		JBrowse link
G Slc19a1 solute carrier family 19 member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr20:11,583,928...11,601,959
Ensembl chr20:11,584,411...11,601,972 		JBrowse link
G Slc1a5 solute carrier family 1 member 5 disease_progression ISO RGD PMID:26279756 RGD:151361150 NCBI chr 1:86,584,949...86,599,052
Ensembl chr 1:77,456,694...77,470,952 		JBrowse link
G Slc22a18 solute carrier family 22, member 18 disease_progression ISO mRNA:increased expression:lung (human)
ClinVar Annotator: match by term: Lung adenocarcinoma		 ClinVar
RGD		 PMID:27993330 PMID:32726996 RGD:150557423 NCBI chr 1:208,100,032...208,124,382
Ensembl chr 1:198,671,731...198,694,975 		JBrowse link
G Slc3a2 solute carrier family 3 member 2 disease_progression ISO RGD PMID:19171406 RGD:151361151 NCBI chr 1:215,033,601...215,048,064
Ensembl chr 1:205,604,468...205,618,931 		JBrowse link
G Slc4a4 solute carrier family 4 member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr14:19,125,394...19,577,379
Ensembl chr14:18,845,159...19,272,883 		JBrowse link
G Slc4a7 solute carrier family 4 member 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr15:13,015,854...13,095,485
Ensembl chr15:10,588,979...10,664,781 		JBrowse link
G Slc7a5 solute carrier family 7 member 5 disease_progression ISO RGD PMID:26279756 PMID:19171406 RGD:151361150, RGD:151361151 NCBI chr19:66,843,808...66,872,412
Ensembl chr19:49,935,220...49,963,823 		JBrowse link
G Smad4 SMAD family member 4 ISO ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:6604412 PMID:8898652 PMID:9214508 PMID:9285566 PMID:9582123 More... NCBI chr18:69,518,988...69,549,684
Ensembl chr18:67,243,742...67,274,438 		JBrowse link
G Smarcc1 SWI/SNF related BAF chromatin remodeling complex subunit C1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 8:118,986,917...119,093,161
Ensembl chr 8:110,111,122...110,214,720 		JBrowse link
G Snord22 small nucleolar RNA, C/D box 22 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr11:22,544,203...22,544,327
Ensembl chr11:9,097,799...9,097,923 		JBrowse link
G Snrpb small nuclear ribonucleoprotein polypeptides B and B1 severity ISO mRNA:increased expression:lung (human) RGD PMID:22876301 RGD:10768834 NCBI chr 3:117,369,816...117,379,344
Ensembl chr 3:117,370,100...117,379,339 		JBrowse link
G Snrpe small nuclear ribonucleoprotein polypeptide E severity ISO mRNA:increased expression:lung (human) RGD PMID:22876301 RGD:10768834 NCBI chr13:47,596,324...47,609,390
Ensembl chr13:45,050,986...45,057,310
Ensembl chr 8:45,050,986...45,057,310 		JBrowse link
G Snrpg small nuclear ribonucleoprotein polypeptide G ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 4:120,369,676...120,377,263
Ensembl chr 4:118,812,252...118,819,826
Ensembl chr  X:118,812,252...118,819,826 		JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr 6:20,286,117...20,363,350
Ensembl chr 6:14,533,360...14,611,107 		JBrowse link
G Sox2 SRY-box transcription factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25184679 NCBI chr 2:119,465,131...119,467,542
Ensembl chr 2:117,536,929...117,539,338 		JBrowse link
G Sox30 SRY-box transcription factor 30 disease_progression ISO RGD PMID:26330328 RGD:11535423 NCBI chr10:30,918,707...30,948,415
Ensembl chr10:30,418,473...30,446,453 		JBrowse link
G Sox4 SRY-box transcription factor 4 ISO protein:increased expression:lung RGD PMID:29882245 RGD:153297792 NCBI chr17:35,876,298...35,881,004
Ensembl chr17:35,667,537...35,673,665 		JBrowse link
G Spop speckle type BTB/POZ protein ameliorates ISO human gene and cell line in mouse model
mRNA, protein:increased expression:lung (human)		 RGD PMID:30607139 PMID:31105033 RGD:153298920, RGD:153298927 NCBI chr10:80,854,890...80,935,781
Ensembl chr10:80,358,124...80,483,955 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase severity ISO RGD PMID:12826049 RGD:150521546 NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Srm spermidine synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 5:164,309,002...164,312,203
Ensembl chr 5:159,025,873...159,029,405 		JBrowse link
G Srr serine racemase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr10:60,267,936...60,285,094
Ensembl chr10:59,769,571...59,787,011 		JBrowse link
G Srsf1 serine and arginine rich splicing factor 1 severity ISO RGD PMID:23071587 RGD:150429662 NCBI chr10:73,335,519...73,342,549
Ensembl chr10:72,839,274...72,845,336 		JBrowse link
G Srsf2 serine and arginine rich splicing factor 2 severity ISO RGD PMID:23071587 RGD:150429662 NCBI chr10:102,550,962...102,554,200
Ensembl chr10:102,052,314...102,055,338 		JBrowse link
G Stk11 serine/threonine kinase 11 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Lung adenocarcinoma		 CTD
ClinVar		 PMID:24793789 PMID:27993330 NCBI chr 7:10,225,204...10,241,965
Ensembl chr 7:9,575,269...9,591,315 		JBrowse link
G Stk39 serine threonine kinase 39 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 3:73,321,522...73,588,397
Ensembl chr 3:52,913,585...53,179,060 		JBrowse link
G Strbp spermatid perinuclear RNA binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 3:41,738,096...41,879,054
Ensembl chr 3:21,337,855...21,414,949 		JBrowse link
G Suclg2 succinate-CoA ligase GDP-forming subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 4:129,623,833...129,893,937
Ensembl chr 4:128,067,033...128,337,170 		JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 ISO DNA:SNP:exon:p.R213H, 638G>A (human) RGD PMID:14688021 RGD:1581441 NCBI chr 1:190,702,592...190,706,112
Ensembl chr 1:181,272,023...181,275,562 		JBrowse link
G Tert telomerase reverse transcriptase susceptibility ISO DNA:SNP: :rs2736098(human)
DNA:SNP::rs33963617(human)
DNA:SNP:: rs2736100(human)
DNA:SNPs:: rs2853669,rs2736108(human)		 RGD PMID:23738012 PMID:31935503 PMID:24761905 PMID:19955392 PMID:23908149 RGD:150530485, RGD:150530635, RGD:150530628, RGD:150530502, RGD:150530498 NCBI chr 1:31,465,766...31,488,650
Ensembl chr 1:29,637,506...29,659,561 		JBrowse link
G Tf transferrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19381893 NCBI chr 8:112,668,667...112,695,376
Ensembl chr 8:103,767,995...103,816,511 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr13:100,691,540...100,793,227
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
G Timm10 translocase of inner mitochondrial membrane 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 3:90,315,048...90,318,613
Ensembl chr 3:69,908,456...69,911,940 		JBrowse link
G Timm8a1 translocase of inner mitochondrial membrane 8A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr  X:102,011,206...102,015,444
Ensembl chr  X:97,717,920...97,721,960 		JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 ISO mRNA:decreased expression:lung (human) RGD PMID:23374247 RGD:151708716 NCBI chr 7:19,408,539...19,459,558
Ensembl chr 7:17,521,919...17,571,839 		JBrowse link
G Tk1 thymidine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr10:103,533,449...103,544,818
Ensembl chr10:103,031,521...103,046,920 		JBrowse link
G Tlr4 toll-like receptor 4 ISO ClinVar Annotator: match by term: Lung adenocarcinoma ClinVar PMID:27993330 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tnfsf10 TNF superfamily member 10 ISO CTD Direct Evidence: therapeutic CTD PMID:24345465 NCBI chr 2:112,136,550...112,155,903
Ensembl chr 2:110,207,916...110,225,135 		JBrowse link
G Tomm40 translocase of outer mitochondrial membrane 40 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 1:88,486,745...88,498,833
Ensembl chr 1:79,358,786...79,370,915 		JBrowse link
G Top2a DNA topoisomerase II alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr10:84,441,954...84,473,093
Ensembl chr10:83,945,735...83,976,874 		JBrowse link
G Tp53 tumor protein p53 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Adenocarcinoma of lung | ClinVar Annotator: match by term: Lung adenocarcinoma		 CTD
ClinVar		 PMID:1565144 PMID:1631137 PMID:2046748 PMID:7732013 PMID:8423216 More... NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tp63 tumor protein p63 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24880342 NCBI chr11:88,343,647...88,554,543
Ensembl chr11:74,838,859...75,049,398 		JBrowse link
G Tpi1 triosephosphate isomerase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 4:159,301,558...159,305,088
Ensembl chr 4:157,615,386...157,619,541 		JBrowse link
G Traf4 Tnf receptor associated factor 4 ISO mRNA:increased expression:lung (human) RGD PMID:29254206 RGD:151665107 NCBI chr10:63,552,251...63,558,356
Ensembl chr10:63,054,181...63,060,284 		JBrowse link
G Ttf1 transcription termination factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25851810 NCBI chr 3:32,782,544...32,807,202
Ensembl chr 3:12,384,655...12,409,257 		JBrowse link
G Ttr transthyretin ISO mRNA,protein:increased expression:lung (human) RGD PMID:26943652 RGD:151665207 NCBI chr18:12,216,684...12,225,972
Ensembl chr18:11,943,789...11,951,008 		JBrowse link
G Tyms thymidylate synthetase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 9:120,760,057...120,776,149
Ensembl chr 9:113,313,452...113,329,536 		JBrowse link
G Ubr5 ubiquitin protein ligase E3 component n-recognin 5 ameliorates ISO human cell line in a mouse model RGD PMID:32867711 RGD:151665200 NCBI chr 7:71,000,197...71,109,841
Ensembl chr 7:69,116,761...69,224,903 		JBrowse link
G Uck2 uridine-cytidine kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr13:81,913,732...81,971,036
Ensembl chr13:79,383,846...79,438,352 		JBrowse link
G Vav1 vav guanine nucleotide exchange factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27158780 NCBI chr 9:2,248,856...2,295,905
Ensembl chr 9:2,157,900...2,208,937 		JBrowse link
G Wrap53 WD repeat containing, antisense to TP53 severity ISO RGD PMID:28347242 RGD:21081522 NCBI chr10:54,780,873...54,797,919
Ensembl chr10:54,282,105...54,298,929 		JBrowse link
G Xpc XPC complex subunit, DNA damage recognition and repair factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:21327329 PMID:27777383 NCBI chr 4:125,550,833...125,578,084
Ensembl chr 4:123,993,666...124,021,010 		JBrowse link
G Xpo1 exportin 1 exacerbates ISO circRNA:increased expression:lung (human) RGD PMID:33268793 RGD:151665799 NCBI chr14:101,434,450...101,476,705
Ensembl chr14:97,233,270...97,275,498 		JBrowse link
G Xrcc1 X-ray repair cross complementing 1 susceptibility
severity		 ISO DNA:missense mutation:cds: p.R399Q (human)
DNA:missense mutation:exon 10: p.R399Q (rs25487) (human)		 RGD PMID:11104903 PMID:20003463 RGD:151347406, RGD:151347422 NCBI chr 1:89,268,721...89,296,619
Ensembl chr 1:80,141,207...80,168,701 		JBrowse link
G Xrcc5 X-ray repair cross complementing 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 9:81,404,507...81,493,293
Ensembl chr 9:73,955,216...74,044,018 		JBrowse link
G Xrcc6 X-ray repair cross complementing 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27602772 NCBI chr 7:115,423,026...115,443,884
Ensembl chr 7:113,543,057...113,563,762 		JBrowse link
G Zfhx3 zinc finger homeobox 3 ameliorates ISO DNA:mutations:multiple (human) RGD PMID:32653938 RGD:151361163 NCBI chr19:52,789,146...53,795,664
Ensembl chr19:36,630,254...36,881,771 		JBrowse link
lung adenoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anapc2 anaphase promoting complex subunit 2 ISO mRNA:decreased expression:lung (human) RGD PMID:14647414 RGD:10047051 NCBI chr 3:28,484,590...28,496,338
Ensembl chr 3:8,086,462...8,098,178 		JBrowse link
G Mir21 microRNA 21 ISO RNA:increased expression:lung: RGD PMID:20956945 RGD:41404697 NCBI chr10:71,902,600...71,902,691
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
lung cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 treatment ISO RGD PMID:35289739 RGD:153344587 NCBI chr10:1,022,041...1,162,431
Ensembl chr10:531,812...655,114 		JBrowse link
G Ace angiotensin I converting enzyme susceptibility ISO DNA:polymorphism (human) RGD PMID:20303010 RGD:4140486 NCBI chr10:91,410,129...91,430,246
Ensembl chr10:90,910,316...90,931,131 		JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 ISO RGD PMID:23936004 RGD:13831302 NCBI chr 9:87,563,601...87,613,078
Ensembl chr 9:80,115,112...80,164,627 		JBrowse link
G Acta2 actin alpha 2, smooth muscle ISO ClinVar Annotator: match by term: LUNG CANCER, SUSCEPTIBILITY TO ClinVar PMID:15937082 PMID:25741868 NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Alk ALK receptor tyrosine kinase ISO ClinVar Annotator: match by term: Lung cancer ClinVar PMID:22277784 PMID:24887559 PMID:25741868 PMID:26939704 PMID:28492532 NCBI chr 6:28,631,431...29,351,321
Ensembl chr 6:22,880,625...23,598,034 		JBrowse link
G Alx4 ALX homeobox 4 ISO DNA:hypermethylation:CpG_island: RGD PMID:24037716 RGD:153344522 NCBI chr 3:100,067,052...100,103,624
Ensembl chr 3:79,611,719...79,648,260 		JBrowse link
G Atm ATM serine/threonine kinase ISO ClinVar Annotator: match by term: Lung cancer ClinVar PMID:25741868 NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Atr ATR serine/threonine kinase treatment ISO RGD PMID:25010037 RGD:150340694 NCBI chr 8:105,306,299...105,403,742
Ensembl chr 8:96,426,724...96,524,136 		JBrowse link
G Axin1 axin 1 disease_progression
treatment		 ISO DNA:hypermethylation
protein:decreased expression:lung (human)
human cells in mouse model		 RGD PMID:23192643 PMID:21496867 PMID:32051824 PMID:23915259 RGD:150527862, RGD:150530293, RGD:150530284, RGD:150530274 NCBI chr10:15,667,894...15,720,092
Ensembl chr10:15,163,684...15,215,615 		JBrowse link
G Axin2 axin 2 susceptibility ISO DNA:SNPs:exons,introns:
DNA:SNP:exon:148T>C(rs2240308)(human)		 RGD PMID:28378643 PMID:25091576 RGD:151356504, RGD:151356659 NCBI chr10:94,393,379...94,426,579
Ensembl chr10:93,899,245...93,926,231 		JBrowse link
G Bard1 BRCA1 associated RING domain 1 ISO ClinVar Annotator: match by term: Lung cancer ClinVar PMID:19197335 PMID:20077502 PMID:25741868 PMID:26467025 PMID:26738429 More... NCBI chr 9:80,069,960...80,144,167
Ensembl chr 9:72,623,155...72,694,265 		JBrowse link
G Bmp2 bone morphogenetic protein 2 ISO ClinVar Annotator: match by term: Lung cancer ClinVar PMID:21515830 PMID:24465802 PMID:26253951 NCBI chr 3:141,264,648...141,275,416
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase ISO ClinVar Annotator: match by term: Lung cancer, somatic
ClinVar Annotator: match by term: EGFR-related lung cancer | ClinVar Annotator: match by term: Lung cancer, somatic		 OMIM
ClinVar		 PMID:16439621 PMID:16474404 PMID:17366577 PMID:17551924 PMID:17703371 More... NCBI chr 4:69,329,772...69,476,931
Ensembl chr 4:68,384,649...68,510,463 		JBrowse link
G Brca1 BRCA1, DNA repair associated ISO ClinVar Annotator: match by term: EGFR-related lung cancer
ClinVar Annotator: match by term: Lung cancer, somatic		 ClinVar PMID:8554067 PMID:9760198 PMID:10486320 PMID:10505028 PMID:11260866 More... NCBI chr10:86,917,693...86,978,012
Ensembl chr10:86,418,000...86,477,304 		JBrowse link
G Calr calreticulin treatment ISO protein:increased expression:blood serum (human)
human cells and recombinant gene in a mouse model		 RGD PMID:26314964 PMID:22083347 PMID:32161598 PMID:12215887 PMID:24111870 RGD:150520159, RGD:150521704, RGD:150521699, RGD:150521700, RGD:150521678 NCBI chr19:40,213,367...40,218,262
Ensembl chr19:23,308,351...23,313,414 		JBrowse link
G Car12 carbonic anhydrase 12 ISO protein:increased expression:serum; RGD PMID:22439015 RGD:155226862 NCBI chr 8:76,169,723...76,225,465
Ensembl chr 8:67,274,359...67,330,440 		JBrowse link
G Casp8 caspase 8 ISO ClinVar Annotator: match by term: Lung cancer | ClinVar Annotator: match by term: Lung cancer, protection against OMIM
ClinVar		 PMID:17450141 PMID:18305469 PMID:25741868 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Ccdc116 coiled-coil domain containing 116 ISO DNA:SNP:promoter:rs3747093 (human) RGD PMID:29193083 RGD:153297750 NCBI chr11:83,842,707...83,850,607
Ensembl chr11:83,845,557...83,850,607 		JBrowse link
G Ccl22 C-C motif chemokine ligand 22 disease_progression ISO RGD PMID:16453150 RGD:4891472 NCBI chr19:10,263,589...10,270,359
Ensembl chr19:10,257,601...10,264,400 		JBrowse link
G Ccng1 cyclin G1 treatment ISO human cells in mouse model RGD PMID:25472877 RGD:151361106 NCBI chr10:25,678,503...25,684,876
Ensembl chr10:25,176,234...25,181,641 		JBrowse link
G Cd164 CD164 molecule exacerbates ISO protein:increased expression:lung (human) RGD PMID:28903328 RGD:11555304 NCBI chr20:46,606,439...46,618,015
Ensembl chr20:45,023,973...45,035,634 		JBrowse link
G Cdc73 cell division cycle 73 exacerbates ISO mRNA:increased expression:lung (human) RGD PMID:29221126 RGD:150539444 NCBI chr13:57,897,924...58,000,031
Ensembl chr13:55,357,226...55,449,656 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B disease_progression IEP protein:decreased expression:lung (rat) RGD PMID:20512841 RGD:152998913 NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C disease_progression IEP
IAGP		 protein:decreased expression:lung (rat)
DNA:hypermethylation:promoter (rat)		 RGD PMID:20512841 PMID:20512841 RGD:152998913, RGD:152998913 NCBI chr 1:208,084,801...208,087,680
Ensembl chr 1:198,655,407...198,658,048 		JBrowse link
G Cftr CF transmembrane conductance regulator susceptibility ISO DNA:deletion, SNP, haplotype: :p.F508del, rs10487372 (human) RGD PMID:20116881 RGD:11566029 NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:46,560,885...46,728,756 		JBrowse link
G Chd4 chromodomain helicase DNA binding protein 4 ameliorates ISO DNA:missense mutation:CDS p.D140E (rs7479004) (human)
mRNA:increased expression:lung (human)		 RGD PMID:30031117 PMID:25407497 RGD:153323309, RGD:153323305 NCBI chr 4:159,584,623...159,617,867
Ensembl chr 4:157,899,391...157,931,541 		JBrowse link
G Chek2 checkpoint kinase 2 ISO ClinVar Annotator: match by term: Lung cancer, somatic ClinVar PMID:16883537 PMID:18484200 PMID:21244692 PMID:21618645 PMID:23318652 More... NCBI chr12:51,448,838...51,481,159
Ensembl chr12:45,788,827...45,821,286 		JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit susceptibility
onset		 ISO associated with smoking; DNA:SNP::rs1051730(human)
ClinVar Annotator: match by term: Lung cancer susceptibility 2
DNA:SNP:exon 2: rs8040868(T>C) (human)
DNA:SNP: :rs6495309(human)
DNA:haplotype:promoter:rs6495309(human)
associated with smoking; DNA:SNP: :rs1051730(human)
DNA:SNP:cds:rs3743073(human)		 OMIM
ClinVar
RGD		 PMID:18385676 PMID:18385738 PMID:18385739 PMID:28492532 PMID:29993116 More... RGD:150526806, RGD:151361155, RGD:151347536, RGD:151347534, RGD:151347455, RGD:151347454 NCBI chr 8:64,297,755...64,311,251
Ensembl chr 8:55,401,702...55,415,165 		JBrowse link
G Chrna5 cholinergic receptor nicotinic alpha 5 subunit susceptibility ISO DNA:SNP::rs16969968 (human)
DNA:SNP:exon, intron:rs1051730, rs1847529 (human)
ClinVar Annotator: match by term: Lung cancer susceptibility 2
DNA:SNP:intron:rs17486278(human)
associated with smoking; DNA:SNP::rs16969968 (human)
DNA:haplotype:promoter		 OMIM
ClinVar
RGD		 PMID:18385738 PMID:18385739 PMID:18618000 PMID:19132693 PMID:19443489 More... RGD:150524357, RGD:153297750, RGD:150527839, RGD:150526806, RGD:150524361 NCBI chr 8:64,265,879...64,294,233
Ensembl chr 8:55,369,794...55,398,146 		JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit disease_progression ISO DNA:CNV:: CNV-3956(human) RGD PMID:25407004 RGD:11074492 NCBI chr 1:126,123,425...126,249,181
Ensembl chr 1:116,714,711...116,837,240 		JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit susceptibility ISO DNA:SNP: :rs7178270(human)
DNA:SNP:3'utr: (rs1948)C>T (human)		 RGD PMID:20587604 PMID:29416783 RGD:150527839, RGD:151361155 NCBI chr 8:64,312,644...64,333,319
Ensembl chr 8:55,418,313...55,437,027 		JBrowse link
G Clptm1l CLPTM1-like disease_progression
sexual_dimorphism
susceptibility		 ISO in males;DNA:SNP: :rs370348(human)
associated with smoking; DNA:SNP:intron:rs31489(human)
DNA:SNPs:: rs402710,rs451360 (human)
DNA:SNPs::multiple (human)		 RGD PMID:27062701 PMID:24366883 PMID:21771723 PMID:21622582 PMID:25422207 More... RGD:150537097, RGD:150530483, RGD:150530643, RGD:150530642, RGD:150530631, RGD:150530494, RGD:150530484 NCBI chr 1:31,496,094...31,512,148
Ensembl chr 1:29,667,545...29,683,530 		JBrowse link
G Comt catechol-O-methyltransferase susceptibility ISO associated with nicotine dependence and alcohol dependence; DNA:SNP:exon 4: 472G>A, p.V158M (rs4680) (human) RGD PMID:27644662 RGD:401959228 NCBI chr11:96,072,371...96,091,956
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Csf1r colony stimulating factor 1 receptor susceptibility
exacerbates		 ISO DNA:missense mutation:CDS:p.H362R (rs10079250) (human)
protein:increased expression:lung (human)		 RGD PMID:25144241 PMID:29323162 RGD:150524283, RGD:150524284 NCBI chr18:56,834,152...56,860,804
Ensembl chr18:54,546,659...54,590,415 		JBrowse link
G Ctnnb1 catenin beta 1 treatment ISO human cells in mouse model RGD PMID:32051824 RGD:150530284 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 ISO associated with Pulmonary Emphysema;DNA:polymorphism: :p.I462V (human) RGD PMID:16696009 RGD:4892075 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 sexual_dimorphism ISO mRNA:increased expression:lung (human)
DNA:SNP:intron: (rs2765934) (human)		 RGD PMID:16180015 PMID:31264381 RGD:151361183, RGD:151665340 NCBI chr 3:179,694,647...179,709,083
Ensembl chr 3:159,275,947...159,290,383 		JBrowse link
G Dab2 DAB adaptor protein 2 disease_progression ISO protein:decreased expression:lung (human) RGD PMID:21496867 RGD:150530293 NCBI chr 2:57,241,947...57,294,893
Ensembl chr 2:55,514,700...55,567,476 		JBrowse link
G Dab2ip DAB2 interacting protein sexual_dimorphism ISO DNA:SNP:intron 1:97906C>A (rs1571801) (human) RGD PMID:22046421 RGD:151665197 NCBI chr 3:39,312,745...39,483,730
Ensembl chr 3:18,915,290...19,086,280 		JBrowse link
G Dagla diacylglycerol lipase, alpha ISO DNA:SNP:rs60507107 (human) RGD PMID:25592173 RGD:151356746 NCBI chr 1:216,315,515...216,372,219
Ensembl chr 1:206,890,638...206,947,232 		JBrowse link
G Dhfr dihydrofolate reductase ISO ClinVar Annotator: match by term: Lung cancer, somatic ClinVar PMID:28492532 NCBI chr 2:25,320,895...25,346,004
Ensembl chr 2:23,586,031...23,613,713 		JBrowse link
G Dicer1 dicer 1 ribonuclease III exacerbates ISO RGD PMID:19903759 RGD:149735199 NCBI chr 6:129,392,298...129,457,252
Ensembl chr 6:123,631,250...123,693,965 		JBrowse link
G Dnai7 dynein axonemal intermediate chain 7 ameliorates ISO DNA:missense mutation:CDS:p.N60S (mouse) RGD PMID:14583591 RGD:152998907 NCBI chr 4:178,143,499...178,179,871
Ensembl chr 4:178,143,500...178,179,980 		JBrowse link
G Dnmt1 DNA methyltransferase 1 disease_progression ISO protein:increased expression:lung:
protein:increased expression:lung (human)		 RGD PMID:24548441 PMID:21496867 RGD:9588658, RGD:150530293 NCBI chr 8:27,716,797...27,763,405
Ensembl chr 8:19,440,611...19,486,659 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha disease_progression ISO protein:increased expression:lung: RGD PMID:24548441 RGD:9588658 NCBI chr 6:32,507,316...32,621,678
Ensembl chr 6:26,822,609...26,896,687 		JBrowse link
G Dnmt3b DNA methyltransferase 3 beta disease_progression ISO protein:increased expression:lung: RGD PMID:24548441 RGD:9588658 NCBI chr 3:162,590,777...162,629,313
Ensembl chr 3:142,130,592...142,169,124 		JBrowse link
G Dvl3 dishevelled segment polarity protein 3 ISO DNA:SNP:intron:rs1969253 (human) RGD PMID:29193083 RGD:153297750 NCBI chr11:93,869,834...93,887,013
Ensembl chr11:80,366,117...80,382,462 		JBrowse link
G Egfr epidermal growth factor receptor susceptibility ISO ClinVar Annotator: match by term: EGFR-related condition | ClinVar Annotator: match by term: EGFR-related lung cancer | ClinVar Annotator: match by term: Lung cancer | ClinVar Annotator: match by term: Lung cancer, somatic
ClinVar Annotator: match by term: Adenocarcinoma of lung, response to tyrosine kinase inhibitor in, somatic | ClinVar Annotator: match by term: EGFR-related condition | ClinVar Annotator: match by term: EGFR-related lung cancer | ClinVar Annotator: match by term: Lung cancer | ClinVar Annotator: match by term: Lung cancer, somatic | ClinVar Annotator: match by term: MAP3K8-related condition		 ClinVar
OMIM		 PMID:7630400 PMID:9536098 PMID:11423618 PMID:15118073 PMID:15118125 More... NCBI chr14:95,378,626...95,551,358
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 ISO ClinVar Annotator: match by term: Lung cancer OMIM
ClinVar		 PMID:25741868 NCBI chr10:83,907,491...83,931,365
Ensembl chr10:83,411,313...83,435,078 		JBrowse link
G Ercc5 ERCC excision repair 5, endonuclease susceptibility ISO mRNA:decreased expression:lung (human) RGD PMID:10910954 RGD:155260338 NCBI chr 9:53,801,471...53,846,611
Ensembl chr 9:46,309,389...46,354,472 		JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor susceptibility
disease_progression
no_association		 ISO DNA:point mutation:promoter::c.-6530C>G (rs3793784) (human)
ClinVar Annotator: match by term: LUNG CANCER, SUSCEPTIBILITY TO | ClinVar Annotator: match by term: Lung cancer | ClinVar Annotator: match by term: Lung cancer, somatic
mRNA:decreased expression:lung (human)
DNA:SNPs: :p.G399D, p.Q1413R (human)
DNA:SNPs: :multiple		 OMIM
ClinVar
RGD		 PMID:887325 PMID:1339317 PMID:9150142 PMID:9443879 PMID:10196384 More... RGD:11561791, RGD:155260338, RGD:11567235, RGD:11567231 NCBI chr16:7,771,311...7,841,895
Ensembl chr16:7,765,013...7,835,587 		JBrowse link
G Esco2 establishment of sister chromatid cohesion N-acetyltransferase 2 severity ISO RGD PMID:33573689 RGD:155791670 NCBI chr15:44,210,124...44,230,785
Ensembl chr15:40,034,568...40,055,306
Ensembl chr15:40,034,568...40,055,306 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit susceptibility ISO DNA:SNPs, haplotype: :rs6950683, rs3757441 (human) RGD PMID:19901851 RGD:126781717 NCBI chr 4:77,624,223...77,698,598
Ensembl chr 4:76,624,399...76,687,362 		JBrowse link
G Fas Fas cell surface death receptor ISO ClinVar Annotator: match by term: LUNG CANCER, SUSCEPTIBILITY TO ClinVar PMID:15937082 PMID:25741868 NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Faslg Fas ligand susceptibility ISO ClinVar Annotator: match by term: Lung cancer | ClinVar Annotator: match by term: Lung cancer, somatic ClinVar
OMIM		 PMID:17605793 PMID:25741868 PMID:26456038 PMID:28492532 NCBI chr13:76,680,885...76,706,042
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Fgf9 fibroblast growth factor 9 ISS OMIM:211980 | OMIM:608935 | OMIM:612571 | OMIM:612593 | OMIM:614210 MouseDO NCBI chr15:36,325,552...36,369,995
Ensembl chr15:32,210,074...32,253,309 		JBrowse link
G Foxa1 forkhead box A1 disease_progression ISO RGD PMID:31221478 RGD:151665930 NCBI chr 6:80,838,380...80,871,195
Ensembl chr 6:75,103,503...75,136,188 		JBrowse link
G Foxm1 forkhead box M1 ISS OMIM:211980 | OMIM:608935 | OMIM:612571 | OMIM:612593 | OMIM:614210 MouseDO NCBI chr 4:163,325,628...163,338,100
Ensembl chr 4:161,638,816...161,650,684 		JBrowse link
G Gata1 GATA binding protein 1 ISO mRNA:increased expression:regulatory T cell:lung associated T cell RGD PMID:28814673 RGD:149735197 NCBI chr  X:17,193,291...17,209,462
Ensembl chr  X:14,529,702...14,537,530 		JBrowse link
G Gpx1 glutathione peroxidase 1 susceptibility
exacerbates		 ISO DNA:missense mutation:CDS:p.P198L (human)
DNA:missense mutation:CDS: (rs1050450) (human)
DNA:mutations:multiple (human)		 RGD PMID:16615267 PMID:23516596 PMID:15192016 PMID:32850411 PMID:11103801 RGD:152023634, RGD:152998903, RGD:152995506, RGD:152995450, RGD:152995449 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Gpx3 glutathione peroxidase 3 treatment ISO RGD PMID:33255360 PMID:26767034 RGD:151708705, RGD:151708707 NCBI chr10:39,529,335...39,537,406
Ensembl chr10:39,028,570...39,037,035 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 resistance ISO RGD PMID:19428374 RGD:4140941 NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Gstt1 glutathione S-transferase theta 1 susceptibility ISO DNA:deletion: : RGD PMID:20542754 RGD:4140924 NCBI chr20:12,856,068...12,873,020
Ensembl chr20:12,856,669...12,873,585 		JBrowse link
G Hnrnpl heterogeneous nuclear ribonucleoprotein L severity ISO human gene in a mouse model RGD PMID:20972334 RGD:9999427 NCBI chr 1:93,226,373...93,239,084
Ensembl chr 1:84,100,879...84,111,553 		JBrowse link
G Hp haptoglobin IEP RGD PMID:19794824 RGD:11041857 NCBI chr19:54,449,151...54,453,701
Ensembl chr19:37,539,627...37,544,523 		JBrowse link
G Hs3st2 heparan sulfate-glucosamine 3-sulfotransferase 2 ISO DNA:hypermethylation:promoter (human) RGD PMID:12527896 RGD:2317633 NCBI chr 1:185,387,445...185,508,700
Ensembl chr 1:175,956,157...176,077,399 		JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 ISO RGD PMID:30128035 RGD:149735564 NCBI chr 1:143,447,925...143,467,248
Ensembl chr 1:134,029,772...134,058,025 		JBrowse link
G Il1r2 interleukin 1 receptor type 2 susceptibility ISO DNA:SNP:CDS:multiple (human) RGD PMID:30895747 RGD:152998976 NCBI chr 9:49,879,928...49,920,374
Ensembl chr 9:42,384,433...42,424,725 		JBrowse link
G Irf1 interferon regulatory factor 1 ISO OMIM NCBI chr10:38,417,935...38,424,946
Ensembl chr10:37,916,670...37,924,166 		JBrowse link
G Irs4 insulin receptor substrate 4 treatment ISO human cells in mouse model RGD PMID:33894221 RGD:151347872 NCBI chr  X:110,132,490...110,148,473 JBrowse link
G Kdm4a lysine demethylase 4A ISO protein:increased expression:lung (human) RGD PMID:23168260 RGD:9587434 NCBI chr 5:136,958,178...137,004,942
Ensembl chr 5:131,672,754...131,719,501 		JBrowse link
G Kdm4b lysine demethylase 4B ISO mRNA, protein:increased expression:lung (human) RGD PMID:21930796 RGD:9587740 NCBI chr 9:1,245,885...1,324,384
Ensembl chr 9:1,158,752...1,236,543 		JBrowse link
G Kdm6a lysine demethylase 6A exacerbates ISO RGD PMID:29632194 RGD:150429738 NCBI chr  X:6,920,374...7,060,027
Ensembl chr  X:4,337,750...4,477,062 		JBrowse link
G Kmt2d lysine methyltransferase 2D ISO ClinVar Annotator: match by term: Lung cancer ClinVar PMID:25741868 NCBI chr 7:131,859,696...131,901,032
Ensembl chr 7:129,962,887...130,020,325 		JBrowse link
G Kras KRAS proto-oncogene, GTPase ISS
ISO		 OMIM:211980 | OMIM:608935 | OMIM:612571 | OMIM:612593 | OMIM:614210
ClinVar Annotator: match by term: EGFR-related lung cancer | ClinVar Annotator: match by term: Lung cancer | ClinVar Annotator: match by term: Lung cancer, somatic
protein:increased expression:lung (human)		 MouseDO
ClinVar
OMIM
RGD		 PMID:1875403 PMID:6320174 PMID:7773929 PMID:8439212 PMID:11745231 More... RGD:153344580 NCBI chr 4:179,916,255...179,949,613 JBrowse link
G Lrp1b LDL receptor related protein 1B severity ISO DNA:mutations: :multiple (human) RGD PMID:33219256 RGD:150429789 NCBI chr 3:45,004,001...47,125,147
Ensembl chr 3:24,594,991...26,715,505 		JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 ameliorates ISO DNA:SNP:promoter: -1304T>G (rs3826392) (human) RGD PMID:20554746 RGD:150429822 NCBI chr10:50,842,348...50,947,063
Ensembl chr10:50,344,915...50,447,993 		JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 exacerbates ISO ClinVar Annotator: match by term: MAP3K8-related condition ClinVar
OMIM
RGD		 PMID:25741868 PMID:28492532 PMID:26300007 RGD:11535492 NCBI chr17:58,078,175...58,098,455
Ensembl chr17:53,383,131...53,403,216 		JBrowse link
G Mat2a methionine adenosyltransferase 2A treatment ISO human cells in mouse model RGD PMID:34258296 RGD:153350142 NCBI chr 4:106,048,043...106,053,612
Ensembl chr 4:104,488,466...104,495,493 		JBrowse link
G Mbd1 methyl-CpG binding domain protein 1 susceptibility ISO DNA:snps, deletion:promoter, cds:g.-634G>A, g.-501delT, p.P401A (human)
DNA:snp::c.1221+135T>A (rs140689) (human)		 RGD PMID:16284366 PMID:18668384 RGD:9588651, RGD:9588657 NCBI chr18:70,145,093...70,159,744
Ensembl chr18:67,869,992...67,886,554 		JBrowse link
G Mbd4 methyl-CpG binding domain 4 DNA glycosylase susceptibility ISO DNA:snp:cds:p.E346K (rs140693) (human) RGD PMID:18495292 RGD:9588970 NCBI chr 4:150,565,646...150,577,433
Ensembl chr 4:148,894,280...148,904,982 		JBrowse link
G Mbl2 mannose binding lectin 2 susceptibility ISO DNA:polymorphisms:multiple (human) RGD PMID:19959685 RGD:4889433 NCBI chr 1:237,429,873...237,465,567 JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member ameliorates ISO human cells in mouse model
DNA:SNP:promoter:-190indel, -235C>A, (rs3831987,rs3738484)
protein:increased expression:lung (human)		 RGD PMID:31662324 PMID:21887682 PMID:28776569 RGD:151356915, RGD:151356991, RGD:151356930 NCBI chr 2:185,884,840...185,912,532
Ensembl chr 2:183,219,220...183,222,303 		JBrowse link
G Mef2d myocyte enhancer factor 2D treatment ISO human cells in mouse model RGD PMID:25472877 RGD:151361106 NCBI chr 2:175,904,332...175,933,451
Ensembl chr 2:173,606,490...173,634,457 		JBrowse link
G Mir122 microRNA 122 treatment ISO human cells in mouse model RGD PMID:25472877 RGD:151361106 NCBI chr18:61,028,817...61,028,901 JBrowse link
G Mir127 microRNA 127 ISO RNA:increased expression:lung (human) RGD PMID:20237410 RGD:152995484 NCBI chr 6:134,328,454...134,328,550
Ensembl chr 6:128,546,215...128,546,311 		JBrowse link
G Mir136 microRNA 136 ameliorates ISO RNA:increased expression:lung (human)
human cells in mouse model		 RGD PMID:20237410 PMID:34258296 RGD:152995484, RGD:153350142 NCBI chr 6:134,331,335...134,331,416
Ensembl chr 6:128,549,096...128,549,177 		JBrowse link
G Mir152 microRNA 152 ISO miRNA:increased expression:plasma RGD PMID:26958084 RGD:21066332 NCBI chr10:82,329,383...82,329,467
Ensembl chr10:81,832,936...81,833,020 		JBrowse link
G Mir193a microRNA 193a ameliorates
treatment		 ISO human cells in mouse model
DNA:hypermethylation		 RGD PMID:27821145 PMID:27669434 PMID:35289739 PMID:29183007 RGD:153344578, RGD:153344606, RGD:153344587, RGD:153344580 NCBI chr10:65,170,306...65,170,417
Ensembl chr10:64,672,343...64,672,454 		JBrowse link
G Mir205 microRNA 205 ISO RNA:increased expression:lung (human) RGD PMID:20237410 RGD:152995484 NCBI chr13:107,564,535...107,564,642
Ensembl chr13:105,035,878...105,035,985 		JBrowse link
G Mir21 microRNA 21 ameliorates ISO RNA:increased expression:blood serum (human) RGD PMID:22638884 PMID:22618808 RGD:152998900, RGD:152998905 NCBI chr10:71,902,600...71,902,691
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mir222 microRNA 222 ameliorates ISO RGD PMID:26909602 RGD:151708998 NCBI chr  X:6,022,621...6,022,723
Ensembl chr  X:3,428,904...3,429,006 		JBrowse link
G Mir31 microRNA 31 disease_progression ISO RNA:increased expression:peripheral blood mononuclear cell (human)
RNA:increased expression:lung (human)		 RGD PMID:20237410 PMID:25765717 RGD:152995484, RGD:152998919 NCBI chr 5:108,714,849...108,714,954 JBrowse link
G Mir337 microRNA 337 ISO RNA:increased expression:lung (human) RGD PMID:20237410 RGD:152995484 NCBI chr 6:134,321,142...134,321,238
Ensembl chr 6:128,538,902...128,538,998 		JBrowse link
G Mir410 microRNA 410 ISO RNA:increased expression:lung (human) RGD PMID:20237410 RGD:152995484 NCBI chr 6:134,579,763...134,579,838
Ensembl chr 6:128,758,354...128,758,434 		JBrowse link
G Mir431 microRNA 431 ISO RNA:increased expression:lung (human) RGD PMID:20237410 RGD:152995484 NCBI chr 6:128,544,210...128,544,323
Ensembl chr 6:128,544,210...128,544,323 		JBrowse link
G Mir98 microRNA 98 treatment ISO RGD PMID:35289739 RGD:153344587 NCBI chr  X:24,460,648...24,460,755
Ensembl chr  X:20,981,235...20,981,342 		JBrowse link
G Mirlet7bhg Mirlet7b host gene susceptibility ISO DNA:SNPs:multiple RGD PMID:26199339 RGD:152998959
G Mki67 marker of proliferation Ki-67 ameliorates ISO human cells in mouse model RGD PMID:29183007 RGD:153344580 NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:190,496,319...190,522,762 		JBrowse link
G Mlh1 mutL homolog 1 susceptibility
no_association		 ISO DNA:SNP:promoter:-93A>G (rs1800734) (human)
ClinVar Annotator: match by term: Lung cancer
DNA:SNP: :rs1800734 (human)
DNA:SNP: :9452A>T (rs1540354) (human)		 ClinVar
RGD		 PMID:25420488 PMID:26845104 PMID:28492532 PMID:30702970 PMID:21093954 More... RGD:126848792, RGD:126848798, RGD:126848792 NCBI chr 8:120,074,871...120,112,109
Ensembl chr 8:111,196,468...111,233,617 		JBrowse link
G Mmp1 matrix metallopeptidase 1 susceptibility ISO DNA:insertion, haplotype:promoter:g.-1607insG (human)
DNA:insertion:promoter:g.-1607insG (human)
associated with Respiratory Tract Diseases		 RGD PMID:19963114 PMID:11691799 PMID:15718477 RGD:4890379, RGD:7207021, RGD:5131088 NCBI chr 8:12,943,453...12,963,966
Ensembl chr 8:4,658,588...4,679,097 		JBrowse link
G Mmp3 matrix metallopeptidase 3 ISO protein:decreased expression:pleural fluid RGD PMID:20216542 RGD:5129491 NCBI chr 8:12,925,267...12,938,828
Ensembl chr 8:4,640,416...4,653,961 		JBrowse link
G Mpo myeloperoxidase ISO associated with Respiratory Tract Diseases
ClinVar Annotator: match by term: Lung cancer, protection against, in smokers		 ClinVar
RGD		 PMID:11087769 PMID:12915675 PMID:15023809 PMID:17304047 PMID:15718477 RGD:5131088 NCBI chr10:73,092,124...73,102,057
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Mpzl3 myelin protein zero-like 3 ISO DNA:SNP:UTR3:rs11216826 (human) RGD PMID:29193083 RGD:153297750 NCBI chr 8:54,257,235...54,277,422
Ensembl chr 8:45,349,054...45,380,662 		JBrowse link
G Msh2 mutS homolog 2 susceptibility ISO DNA:SNP: :rs2303425 (human) RGD PMID:25252909 RGD:126848798 NCBI chr 6:12,567,368...12,626,534
Ensembl chr 6:6,813,795...6,872,938 		JBrowse link
G Msh3 mutS homolog 3 ISO ClinVar Annotator: match by term: Lung cancer, somatic ClinVar PMID:28492532 NCBI chr 2:25,179,400...25,320,857 JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor treatment ISO human cells in mouse model RGD PMID:32051824 RGD:150530284 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor exacerbates ISO human cell line in a mouse model RGD PMID:22938463 RGD:150521529 NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Nat2 N-acetyltransferase 2 no_association
susceptibility		 ISO DNA:polymorphisms: : RGD PMID:15808403 PMID:19558213 RGD:5131861, RGD:5131605 NCBI chr16:26,974,874...27,005,191
Ensembl chr16:22,208,194...22,238,520 		JBrowse link
G Ncoa6 nuclear receptor coactivator 6 ISO DNA:amplification:cds (human) RGD PMID:10567404 RGD:9590137 NCBI chr 3:164,351,062...164,422,079
Ensembl chr 3:143,890,896...143,952,268 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 ISO ClinVar Annotator: match by term: EGFR-related lung cancer ClinVar NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 disease_progression
exacerbates		 ISO RGD PMID:26300007 PMID:26300007 RGD:11535492, RGD:11535492 NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nfkbia NFKB inhibitor alpha susceptibility ISO DNA:polymorphisms:promoter:-826C>T,-881A>G (human) RGD PMID:26870106 RGD:13793394 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 susceptibility ISO DNA:insertion: : 3020_3021insC (human) RGD PMID:16267612 RGD:5131514 NCBI chr19:34,555,832...34,596,281
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Palb2 partner and localizer of BRCA2 ISO ClinVar Annotator: match by term: Lung cancer, somatic ClinVar PMID:17200668 PMID:17200671 PMID:17200672 PMID:24136930 PMID:25099575 More... NCBI chr 1:186,096,312...186,120,284
Ensembl chr 1:176,665,076...176,688,990 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha ISO ClinVar Annotator: match by term: EGFR-related lung cancer
ClinVar Annotator: match by term: Lung cancer, somatic		 ClinVar
OMIM		 PMID:19366826 PMID:25157968 PMID:25741868 PMID:26619011 PMID:28492532 NCBI chr 2:117,103,643...117,177,411
Ensembl chr 2:115,174,984...115,249,032 		JBrowse link
G Plcg1 phospholipase C, gamma 1 exacerbates ISO RGD PMID:33077911 RGD:151356960 NCBI chr 3:169,805,299...169,836,040
Ensembl chr 3:149,385,587...149,416,330 		JBrowse link
G Pml PML nuclear body scaffold ameliorates ISO RGD PMID:25486572 RGD:41404692 NCBI chr 8:67,523,164...67,557,801
Ensembl chr 8:58,628,837...58,658,971 		JBrowse link
G Pole DNA polymerase epsilon, catalytic subunit severity ISO DNA:missense mutation:CDS:p.A252V (human) RGD PMID:17855454 RGD:11567235 NCBI chr12:52,005,155...52,053,761
Ensembl chr12:46,345,420...46,393,939 		JBrowse link
G Pot1 protection of telomeres 1 ISO DNA:SNP: : rs10244817 (human)
DNA:SNP: :rs116895242 (human)
DNA:SNP: :p.V326A (rs75932146) (human) 		RGD PMID:19285750 PMID:27459707 PMID:32514122 RGD:151356947, RGD:151356949, RGD:151356948 NCBI chr 4:55,170,821...55,228,588
Ensembl chr 4:54,205,332...54,263,042 		JBrowse link
G Ppp2r1b protein phosphatase 2 scaffold subunit A beta ISO ClinVar Annotator: match by term: PPP2R1B-related condition OMIM
ClinVar		 NCBI chr 8:60,092,540...60,125,512
Ensembl chr 8:51,186,717...51,228,485 		JBrowse link
G Prdm1 PR/SET domain 1 disease_progression ISO RGD PMID:28378641 RGD:150530469 NCBI chr20:49,542,465...49,564,088
Ensembl chr20:47,959,858...47,981,488 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase ISO ClinVar Annotator: match by term: Lung cancer | ClinVar Annotator: match by term: Lung cancer, somatic OMIM
ClinVar		 PMID:10072423 PMID:10824074 PMID:11179010 PMID:11558785 PMID:11889248 More... NCBI chr 1:51,236,410...52,430,242
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IMP RGD PMID:21303331 RGD:5135048 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rac1 Rac family small GTPase 1 treatment ISO DNA:SNPs:enhancers, intron: (rs836554, rs4720672, rs12536544) (human) RGD PMID:27299748 RGD:155230814 NCBI chr12:16,150,411...16,170,864
Ensembl chr12:11,036,698...11,057,251 		JBrowse link
G Rad52 RAD52 homolog, DNA repair protein susceptibility ISO DNA:SNP,haplotype:
DNA:SNP: (rs4766394) (human)		 RGD PMID:18449888 PMID:22382497 RGD:151660351, RGD:151660503 NCBI chr 4:154,778,320...154,802,002
Ensembl chr 4:153,106,062...153,128,207 		JBrowse link
G Rbm10 RNA binding motif protein 10 onset ISO RGD PMID:33219256 RGD:150429789 NCBI chr  X:4,093,914...4,126,060
Ensembl chr  X:1,540,398...1,572,575 		JBrowse link
G Recql RecQ like helicase ISO RGD PMID:18422747 RGD:2317370 NCBI chr 4:177,039,351...177,063,968
Ensembl chr 4:175,304,117...175,332,945 		JBrowse link
G Rictor RPTOR independent companion of MTOR, complex 2 ISO DNA:amplification: :lung (human) RGD PMID:26370156 RGD:11535413 NCBI chr 2:57,539,279...57,631,291
Ensembl chr 2:55,811,322...55,901,426 		JBrowse link
G Rnaset2 ribonuclease T2 ISO DNA:SNP:intergenic:rs444210 (human) RGD PMID:29193083 RGD:153297750 NCBI chr 1:52,576,344...52,603,151
Ensembl chr 1:52,585,929...52,603,147 		JBrowse link
G Robo1 roundabout guidance receptor 1 ISS OMIM:211980 | OMIM:608935 | OMIM:612571 | OMIM:612593 | OMIM:614210 MouseDO NCBI chr11:24,067,869...25,108,694
Ensembl chr11:10,580,908...11,620,203 		JBrowse link
G Rtel1 regulator of telomere elongation helicase 1 ameliorates
susceptibility		 ISO DNA:SNP:cds:rs2738789 (human)
DNA:SNP:cds:rs7261546|rs6062299|rs3787098 (human)		 RGD PMID:27765928 PMID:27765928 RGD:152993553, RGD:152993553 NCBI chr 3:188,778,329...188,842,877
Ensembl chr 3:168,419,579...168,465,348 		JBrowse link
G Setdb1 SET domain bifurcated histone lysine methyltransferase 1 severity ISO human gene in a mouse model RGD PMID:23770855 RGD:9590160 NCBI chr 2:185,587,722...185,619,084
Ensembl chr 2:182,898,738...182,930,506 		JBrowse link
G Sftpb surfactant protein B disease_progression ISO RGD PMID:24248694 PMID:28743125 RGD:151667422, RGD:151667423 NCBI chr 4:105,917,495...105,926,631
Ensembl chr 4:104,359,396...104,368,436 		JBrowse link
G Shox2 SHOX homeobox 2 ISO RGD PMID:25331797 RGD:12859082 NCBI chr 2:153,524,324...153,537,571
Ensembl chr 2:151,217,552...151,227,143 		JBrowse link
G Slc19a1 solute carrier family 19 member 1 ISO ClinVar Annotator: match by term: Lung cancer, somatic ClinVar PMID:15457444 PMID:15677700 PMID:17325736 PMID:18322994 PMID:19827168 More... NCBI chr20:11,583,928...11,601,959
Ensembl chr20:11,584,411...11,601,972 		JBrowse link
G Slc22a18 solute carrier family 22, member 18 ISO OMIM NCBI chr 1:208,100,032...208,124,382
Ensembl chr 1:198,671,731...198,694,975 		JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 ISO mRNA:increased expression:lung (human) RGD PMID:25625007 RGD:152995427 NCBI chr 4:176,282,577...176,355,557
Ensembl chr 4:174,551,480...174,619,981 		JBrowse link
G Smad3 SMAD family member 3 ISO ClinVar Annotator: match by term: Lung cancer ClinVar PMID:21515830 PMID:24465804 PMID:26253951 NCBI chr 8:73,022,204...73,132,324
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
G Smad4 SMAD family member 4 ISO ClinVar Annotator: match by term: Lung cancer ClinVar PMID:21515830 PMID:24465805 PMID:25741868 PMID:26253951 NCBI chr18:69,518,988...69,549,684
Ensembl chr18:67,243,742...67,274,438 		JBrowse link
G Smad9 SMAD family member 9 ISO ClinVar Annotator: match by term: Lung cancer ClinVar PMID:21515830 PMID:24465803 PMID:26253951 NCBI chr 2:141,106,668...141,156,477
Ensembl chr 2:138,986,471...139,006,307 		JBrowse link
G Sod2 superoxide dismutase 2 ISO RGD PMID:15213518 RGD:1581247 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sox30 SRY-box transcription factor 30 exacerbates ISO DNA:hypermethylation:lung: RGD PMID:25435374 PMID:25435374 RGD:151660338, RGD:151660338 NCBI chr10:30,918,707...30,948,415
Ensembl chr10:30,418,473...30,446,453 		JBrowse link
G Sox9 SRY-box transcription factor 9 disease_progression ISO mRNA:increased expression:lung RGD PMID:31221478 PMID:31221478 RGD:151665930, RGD:151665930 NCBI chr10:98,305,744...98,311,250
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
G Srsf6 serine and arginine rich splicing factor 6 ISO mRNA:increased expression:lung (human) RGD PMID:23132731 RGD:11039482 NCBI chr 3:172,009,072...172,014,395
Ensembl chr 3:151,589,535...151,594,860 		JBrowse link
G Stim1 stromal interaction molecule 1 ameliorates ISO human cells in mouse model RGD PMID:27863410 RGD:152995356 NCBI chr 1:166,067,450...166,230,733
Ensembl chr 1:156,656,013...156,818,363 		JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 ISO DNA:SNP:exon:p.R213H, 638G>A (human) RGD PMID:14688021 RGD:1581441 NCBI chr 1:190,702,592...190,706,112
Ensembl chr 1:181,272,023...181,275,562 		JBrowse link
G Tert telomerase reverse transcriptase ISO mRNA:increased expression:lung RGD PMID:10969652 RGD:152977758 NCBI chr 1:31,465,766...31,488,650
Ensembl chr 1:29,637,506...29,659,561 		JBrowse link
G Tnc tenascin C ISO protein:increased expression:lung RGD PMID:16928692 RGD:4889612 NCBI chr 5:82,391,340...82,476,197
Ensembl chr 5:77,375,851...77,460,624 		JBrowse link
G Tp63 tumor protein p63 ISO DNA:SNP:intron:rs12696594 (human) RGD PMID:29193083 RGD:153297750 NCBI chr11:88,343,647...88,554,543
Ensembl chr11:74,838,859...75,049,398 		JBrowse link
G Tp73 tumor protein p73 susceptibility ISO DNA:SNPs:exon 2:4G>A, 14C>T (human) RGD PMID:11139314 PMID:32063627 RGD:2291830, RGD:151347583 NCBI chr 5:169,903,801...169,988,075
Ensembl chr 5:164,621,377...164,681,128 		JBrowse link
G Trpc4 transient receptor potential cation channel, subfamily C, member 4 susceptibility ISO DNA:SNPs:: (rs9547991, rs978156) (human) RGD PMID:27617218 RGD:152995362 NCBI chr 2:140,457,841...140,629,556
Ensembl chr 2:138,308,084...138,476,768 		JBrowse link
G Trpc7 transient receptor potential cation channel, subfamily C, member 7 susceptibility ISO DNA:SNPs:: (rs11748198) (human) RGD PMID:27617218 RGD:152995362 NCBI chr17:7,708,911...7,833,435
Ensembl chr17:7,709,583...7,833,435 		JBrowse link
G Ttr transthyretin sexual_dimorphism
disease_progression		 ISO protein:decreased expression:blood serum (human) RGD PMID:17683510 PMID:20964562 RGD:151664742, RGD:151664750 NCBI chr18:12,216,684...12,225,972
Ensembl chr18:11,943,789...11,951,008 		JBrowse link
G Wt1 WT1 transcription factor ISO mRNA:decreased expression:lung (human) RGD PMID:27821145 RGD:153344578 NCBI chr 3:112,019,721...112,068,454
Ensembl chr 3:91,567,001...91,613,643 		JBrowse link
G Xpc XPC complex subunit, DNA damage recognition and repair factor ISS OMIM:211980 | OMIM:608935 | OMIM:612571 | OMIM:612593 | OMIM:614210 MouseDO NCBI chr 4:125,550,833...125,578,084
Ensembl chr 4:123,993,666...124,021,010 		JBrowse link
G Xrcc1 X-ray repair cross complementing 1 susceptibility
no_association
onset
severity		 ISO DNA:SNP:exon 10: c.1178G>A, p.R393H (human)
DNA:missense mutation:exon 10: p.R399Q (rs25487) (human)
DNA:missense mutation:cds: p.R399Q (human)
DNA:SNP, haplotype:5'utr: 77T>C (rs3213245) (human)
DNA:missense mutations:cds: p.R399Q, p.R194W (human)
DNA:SNPs, haplotypes:exon 6, exon 7: p.R194W, p.P206P (rs179978, rs915927) (human)
DNA:missense mutation:exon 10: p.R399Q (human)
DNA:missense mutation:exon 10: p.R399Q, 28152G>A (human)
DNA:missense mutation:exon 17: c.1804C>A, p.P602T (human)		 RGD PMID:24935603 PMID:25038912 PMID:15705867 PMID:16652158 PMID:17531525 More... RGD:11056906, RGD:151347450, RGD:151347439, RGD:151232296, RGD:151347426, RGD:151347416, RGD:151347407, RGD:151347172, RGD:151236316 NCBI chr 1:89,268,721...89,296,619
Ensembl chr 1:80,141,207...80,168,701 		JBrowse link
G Xrn2 5'-3' exoribonuclease 2 susceptibility ISO DNA:snp:intron:c.2171-314T>C (rs2025811) (human) RGD PMID:19915612 RGD:11041753 NCBI chr 3:154,888,558...154,962,519
Ensembl chr 3:134,437,109...134,509,306 		JBrowse link
Lung Carcinoid Tumors term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atrx ATRX, chromatin remodeler disease_progression ISO protein:decreased expression:nucleus, lung RGD PMID:31499081 RGD:127285379 NCBI chr  X:74,916,548...75,062,880
Ensembl chr  X:70,850,981...70,997,330 		JBrowse link
G Col4a3 collagen type IV alpha 3 chain severity ISO mRNA:decreased expression:lung (human) RGD PMID:25105010 RGD:151660336 NCBI chr 9:91,323,990...91,453,088
Ensembl chr 9:83,875,561...84,001,895 		JBrowse link
G Creb5 cAMP responsive element binding protein 5 severity ISO mRNA:decreased expression:lung (human) RGD PMID:25105010 RGD:151660336 NCBI chr 4:83,723,587...84,124,786
Ensembl chr 4:82,393,730...82,790,325 		JBrowse link
G Men1 menin 1 ISO ClinVar Annotator: match by term: Lung carcinoid tumor ClinVar PMID:9215689 PMID:9361035 PMID:9463336 PMID:9709921 PMID:10595737 More... NCBI chr 1:213,068,166...213,074,132
Ensembl chr 1:203,639,000...203,644,871 		JBrowse link
G Ptprb protein tyrosine phosphatase, receptor type, B severity ISO mRNA:decreased expression:lung (human) RGD PMID:25105010 RGD:151660336 NCBI chr 7:53,816,197...53,920,760
Ensembl chr 7:51,930,015...52,034,748 		JBrowse link
lung carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme ISO protein:decreased activity:serum (human) RGD PMID:183595 RGD:40400721 NCBI chr10:91,410,129...91,430,246
Ensembl chr10:90,910,316...90,931,131 		JBrowse link
G Apoe apolipoprotein E ISO RGD PMID:24175756 RGD:11040551 NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Arhgap44 Rho GTPase activating protein 44 ISO mRNA:decreased expression:lung (human) RGD PMID:28527113 RGD:401901290 NCBI chr10:50,154,724...50,322,027
Ensembl chr10:49,655,584...49,824,297 		JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase ISO ClinVar Annotator: match by term: Lung carcinoma ClinVar PMID:11313766 PMID:16007634 PMID:17437909 PMID:17704260 PMID:18042262 More... NCBI chr 4:69,329,772...69,476,931
Ensembl chr 4:68,384,649...68,510,463 		JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit susceptibility ISO DNA:SNP: :rs1051730(human) RGD PMID:24337855 RGD:151347533 NCBI chr 8:64,297,755...64,311,251
Ensembl chr 8:55,401,702...55,415,165 		JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein ISO RGD PMID:16391854 RGD:7488899 NCBI chr11:97,033,033...97,067,457
Ensembl chr11:83,526,530...83,563,238 		JBrowse link
G Ctnna1 catenin alpha 1 IEP RGD PMID:15195114 RGD:2289804 NCBI chr18:27,002,330...27,135,009
Ensembl chr18:26,728,485...26,860,910 		JBrowse link
G Ctnnb1 catenin beta 1 disease_progression IAGP DNA, protein:mutations, increased expression:cytoplasm, nucleus:multiple RGD PMID:17639448 RGD:2289843 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 susceptibility ISO DNA:SNP:3' utr: (rs4809957) (human) RGD PMID:22797725 RGD:151665791 NCBI chr 3:179,694,647...179,709,083
Ensembl chr 3:159,275,947...159,290,383 		JBrowse link
G Dnmt1 DNA methyltransferase 1 disease_progression IDA protein:increased expression:nucleus: RGD PMID:21163286 RGD:9588222 NCBI chr 8:27,716,797...27,763,405
Ensembl chr 8:19,440,611...19,486,659 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha disease_progression IDA protein:increased expression:nucleus: RGD PMID:21163286 RGD:9588222 NCBI chr 6:32,507,316...32,621,678
Ensembl chr 6:26,822,609...26,896,687 		JBrowse link
G Egfr epidermal growth factor receptor ISO ClinVar Annotator: match by term: Lung carcinoma ClinVar PMID:15118073 PMID:15118125 PMID:15329413 PMID:15623594 PMID:15788655 More... NCBI chr14:95,378,626...95,551,358
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit IDA RGD PMID:21530494 RGD:10045659 NCBI chr 1:88,099,308...88,135,966
Ensembl chr 1:78,996,390...79,007,963 		JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor ISO ClinVar Annotator: match by term: Lung carcinoma ClinVar PMID:9443879 PMID:10196384 PMID:18414213 PMID:18628313 PMID:18784753 More... NCBI chr16:7,771,311...7,841,895
Ensembl chr16:7,765,013...7,835,587 		JBrowse link
G Foxa1 forkhead box A1 ameliorates ISO RGD PMID:31221478 RGD:151665930 NCBI chr 6:80,838,380...80,871,195
Ensembl chr 6:75,103,503...75,136,188 		JBrowse link
G Gpx3 glutathione peroxidase 3 ISO protein decreased expression:heart RGD PMID:33693448 RGD:401827836 NCBI chr10:39,529,335...39,537,406
Ensembl chr10:39,028,570...39,037,035 		JBrowse link
G Jak2 Janus kinase 2 treatment ISO human cells in mouse model RGD PMID:26397387 RGD:11529462 NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Kdr kinase insert domain receptor treatment ISO RGD PMID:20118536 PMID:16763608 RGD:126925177, RGD:126925190 NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,217,871...32,261,018 		JBrowse link
G Kras KRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Lung carcinoma ClinVar PMID:6320174 PMID:11745231 PMID:15696205 PMID:16051643 PMID:16474404 More... NCBI chr 4:179,916,255...179,949,613 JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 exacerbates ISO DNA:missense mutation:CDS:p.E116K (human) RGD PMID:27028764 RGD:11529413 NCBI chr12:7,389,032...7,398,377
Ensembl chr12:2,591,219...2,604,222 		JBrowse link
G Mdc1 mediator of DNA damage checkpoint 1 ISO protein:decreased expression:bronchus, parenchyma (human) RGD PMID:17546051 RGD:9589053 NCBI chr20:2,898,496...2,914,960
Ensembl chr20:2,895,505...2,910,240 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase ISO ClinVar Annotator: match by term: Lung carcinoma ClinVar PMID:26637977 PMID:26892698 NCBI chr 4:46,756,823...46,864,041
Ensembl chr 4:45,790,791...45,897,876 		JBrowse link
G Mir21 microRNA 21 ISO RNA:increased expression:lung: RGD PMID:20956945 RGD:41404697 NCBI chr10:71,902,600...71,902,691
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mir222 microRNA 222 treatment ISO RGD PMID:27566197 RGD:151893461 NCBI chr  X:6,022,621...6,022,723
Ensembl chr  X:3,428,904...3,429,006 		JBrowse link
G Mlh1 mutL homolog 1 IDA RGD PMID:21530494 RGD:10045659 NCBI chr 8:120,074,871...120,112,109
Ensembl chr 8:111,196,468...111,233,617 		JBrowse link
G Muc4 mucin 4, cell surface associated ISO protein:altered expression:lung RGD PMID:11596032 RGD:5131258 NCBI chr11:81,513,321...81,575,200 JBrowse link
G Pfas phosphoribosylformylglycinamidine synthase ISO RGD PMID:6722784 RGD:5135276 NCBI chr10:54,189,157...54,210,685
Ensembl chr10:53,691,626...53,708,420 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha ISO ClinVar Annotator: match by term: Lung carcinoma ClinVar PMID:17376864 PMID:22729222 PMID:22729224 PMID:24033266 PMID:25741868 More... NCBI chr 2:117,103,643...117,177,411
Ensembl chr 2:115,174,984...115,249,032 		JBrowse link
G Ppm1d protein phosphatase, Mg2+/Mn2+ dependent, 1D ISO ClinVar Annotator: match by term: Lung carcinoma ClinVar PMID:23907125 PMID:24262437 PMID:25741868 PMID:28343630 PMID:28492532 More... NCBI chr10:70,670,026...70,706,030
Ensembl chr10:70,172,603...70,208,607 		JBrowse link
G Ppp2r1b protein phosphatase 2 scaffold subunit A beta ISO ClinVar Annotator: match by term: Lung carcinoma ClinVar PMID:9765152 PMID:11996789 NCBI chr 8:60,092,540...60,125,512
Ensembl chr 8:51,186,717...51,228,485 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase ISO ClinVar Annotator: match by term: Lung carcinoma ClinVar PMID:10072423 PMID:11558785 PMID:11889248 PMID:12114481 PMID:12730996 More... NCBI chr 1:51,236,410...52,430,242
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Slc22a18 solute carrier family 22, member 18 ISO ClinVar Annotator: match by term: Lung carcinoma ClinVar PMID:9751628 NCBI chr 1:208,100,032...208,124,382
Ensembl chr 1:198,671,731...198,694,975 		JBrowse link
G Sox9 SRY-box transcription factor 9 exacerbates ISO RGD PMID:31221478 RGD:151665930 NCBI chr10:98,305,744...98,311,250
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
G Strap serine/threonine kinase receptor associated protein ISO RGD PMID:16778189 RGD:1581429 NCBI chr 4:170,646,042...170,660,291
Ensembl chr 4:170,646,001...170,660,828 		JBrowse link
G Xpo1 exportin 1 ameliorates ISO human cell line in a mouse model RGD PMID:25629636 RGD:11058563 NCBI chr14:101,434,450...101,476,705
Ensembl chr14:97,233,270...97,275,498 		JBrowse link
lung large cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgap44 Rho GTPase activating protein 44 ISO mRNA:decreased expression:lung (human) RGD PMID:28527113 RGD:401901290 NCBI chr10:50,154,724...50,322,027
Ensembl chr10:49,655,584...49,824,297 		JBrowse link
G Chrna5 cholinergic receptor nicotinic alpha 5 subunit ISO mRNA:increased expression:lung RGD PMID:20124469 RGD:150527851 NCBI chr 8:64,265,879...64,294,233
Ensembl chr 8:55,369,794...55,398,146 		JBrowse link
G Dll4 delta like canonical Notch ligand 4 treatment IEP RGD PMID:33628824 RGD:155663482 NCBI chr 3:126,770,945...126,780,769
Ensembl chr 3:106,316,986...106,326,931 		JBrowse link
G Notch1 notch receptor 1 treatment IEP RGD PMID:33628824 RGD:155663482 NCBI chr 3:29,676,040...29,721,613
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Ptpn13 protein tyrosine phosphatase, non-receptor type 13 ISO mRNA,protein:decreased expression:lung RGD PMID:22245727 RGD:152176663 NCBI chr14:6,412,841...6,587,238
Ensembl chr14:6,108,211...6,282,563 		JBrowse link
G Ttr transthyretin ISO protein:increased expression:lung (human) RGD PMID:26943652 RGD:151665207 NCBI chr18:12,216,684...12,225,972
Ensembl chr18:11,943,789...11,951,008 		JBrowse link
lung metastasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam28 ADAM metallopeptidase domain 28 ameliorates ISO associated with lung carcinoma, breast carcinoma
associated with lung adenocarcinoma;		 RGD PMID:22636800 PMID:26800504 RGD:153297785, RGD:11531771 NCBI chr15:50,184,286...50,250,605
Ensembl chr15:42,944,467...43,840,672 		JBrowse link
G Arhgap5 Rho GTPase activating protein 5 ISO associated with Mammary Neoplasms, Experimental RGD PMID:20860838 RGD:126848767 NCBI chr 6:75,711,199...75,774,636
Ensembl chr 6:69,976,214...70,037,660 		JBrowse link
G Arid2 AT-rich interaction domain 2 exacerbates ISO associated with hepatocellular carcinoma, RGD PMID:32071245 RGD:150340708 NCBI chr 7:129,326,371...129,443,813
Ensembl chr 7:127,447,278...127,563,512 		JBrowse link
G Azgp1 alpha-2-glycoprotein 1, zinc-binding ameliorates ISO associated with hepatocellular carcinoma; RGD PMID:27993894 PMID:26902423 RGD:153350132, RGD:153350133 NCBI chr12:22,044,685...22,051,248
Ensembl chr12:16,931,024...16,939,091 		JBrowse link
G Car12 carbonic anhydrase 12 ameliorates ISO associated with breast cancer; RGD PMID:29786141 RGD:155226861 NCBI chr 8:76,169,723...76,225,465
Ensembl chr 8:67,274,359...67,330,440 		JBrowse link
G Cblb Cbl proto-oncogene B severity ISO associated with stomach carcinoma; RGD PMID:28334634 RGD:150540337 NCBI chr11:62,058,829...62,225,904
Ensembl chr11:48,592,703...48,756,839 		JBrowse link
G Ccng1 cyclin G1 ISO RGD PMID:30565428 RGD:151361205 NCBI chr10:25,678,503...25,684,876
Ensembl chr10:25,176,234...25,181,641 		JBrowse link
G Chd4 chromodomain helicase DNA binding protein 4 ameliorates ISO associated with human colon adenocarcinoma cells in a mouse model RGD PMID:28486105 RGD:153323299 NCBI chr 4:159,584,623...159,617,867
Ensembl chr 4:157,899,391...157,931,541 		JBrowse link
G Col10a1 collagen type X alpha 1 chain ameliorates ISO associated with H1299 cell RGD PMID:33324550 RGD:150429752 NCBI chr20:39,737,536...39,744,518
Ensembl chr20:38,182,494...38,189,494 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 ameliorates ISO associated with colorectal cancer; human cells in mouse model
associated with osteosarcoma and melanoma
associated with nasopharynx carcinoma; human cells in mouse model		 RGD PMID:31938138 PMID:18071913 PMID:26498029 PMID:16000558 RGD:151665329, RGD:152177473, RGD:152023752, RGD:151893515 NCBI chr13:42,630,383...42,634,288
Ensembl chr13:40,077,976...40,081,883 		JBrowse link
G Ddr1 discoidin domain receptor tyrosine kinase 1 ISO RGD PMID:29483153 RGD:151347599 NCBI chr20:3,047,269...3,069,277
Ensembl chr20:3,044,320...3,064,468 		JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 exacerbates ISO associated with tongue squamous cell carcinoma; RGD PMID:24556606 RGD:150429746 NCBI chr13:84,726,412...84,851,032
Ensembl chr13:82,195,463...82,317,363 		JBrowse link
G Fasn fatty acid synthase ISO associated with head and neck squamous cell carcinoma RGD PMID:20604875 RGD:126790467 NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit ISO human cells in mouse model RGD PMID:30326930 RGD:153344557 NCBI chr 6:30,017,952...30,039,269
Ensembl chr 6:24,300,956...24,320,034 		JBrowse link
G Hilpda hypoxia inducible lipid droplet-associated ISO human cells in mouse model RGD PMID:31142329 RGD:153344574 NCBI chr 4:58,836,463...58,839,423
Ensembl chr 4:57,871,110...57,874,557 		JBrowse link
G Iqsec1 IQ motif and Sec7 domain ArfGEF 1 ISO human cells in mouse model RGD PMID:18084281 RGD:153344604 NCBI chr 4:124,725,917...125,045,351
Ensembl chr 4:123,168,719...123,488,172 		JBrowse link
G Itgav integrin subunit alpha V treatment ISO human cells in rat model RGD PMID:20841470 RGD:152998949 NCBI chr 3:89,245,382...89,333,512
Ensembl chr 3:68,838,189...68,926,639 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 ameliorates ISO associated with breast carcinoma RGD PMID:16568086 RGD:150573808 NCBI chr 2:45,081,889...45,150,555
Ensembl chr 2:43,350,098...43,414,463 		JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 ameliorates ISO associated with clear cell renal cell carcinoma RGD PMID:23982215 RGD:151356974 NCBI chr17:58,078,175...58,098,455
Ensembl chr17:53,383,131...53,403,216 		JBrowse link
G Mir423 microRNA 423 ISO human cells in mouse model RGD PMID:30326930 RGD:153344557 NCBI chr10:62,412,272...62,412,350
Ensembl chr10:61,914,133...61,914,226 		JBrowse link
G Mir494 microRNA 494 ameliorates ISO associated with hepatocellular carcinoma RGD PMID:25820676 PMID:28055013 RGD:155900754, RGD:156430322 NCBI chr 6:134,550,115...134,550,197
Ensembl chr 6:128,728,709...128,728,793 		JBrowse link
G Nf2 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor ISO associated with hepatocellular carcinoma RGD PMID:26443326 RGD:11076529 NCBI chr14:83,850,894...83,934,263
Ensembl chr14:79,627,399...79,710,667 		JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 ameliorates ISO associated with mammary carcinoma RGD PMID:20802235 RGD:150520014 NCBI chr 1:141,526,192...141,913,575
Ensembl chr 1:132,132,849...132,503,286 		JBrowse link
G Pagr1 Paxip1-associated glutamate-rich protein 1 ISO human cells in mouse model RGD PMID:33833989 RGD:153344568 NCBI chr 1:191,053,228...191,055,554 JBrowse link
G Ptprb protein tyrosine phosphatase, receptor type, B treatment ISO RGD PMID:23899555 RGD:151660352 NCBI chr 7:53,816,197...53,920,760
Ensembl chr 7:51,930,015...52,034,748 		JBrowse link
G Rictor RPTOR independent companion of MTOR, complex 2 ISO human cells in mouse model RGD PMID:20978191 PMID:29809146 RGD:152995469, RGD:152995516 NCBI chr 2:57,539,279...57,631,291
Ensembl chr 2:55,811,322...55,901,426 		JBrowse link
G Rptor regulatory associated protein of MTOR, complex 1 ISO RGD PMID:29809146 RGD:152995516 NCBI chr10:105,376,943...105,675,416
Ensembl chr10:104,878,487...105,176,983 		JBrowse link
G Sf3b4 splicing factor 3B subunit 4 ISO human cells in mouse model RGD PMID:30391496 RGD:155804298 NCBI chr 2:186,421,667...186,426,419
Ensembl chr 2:183,732,754...183,737,959 		JBrowse link
G Sox30 SRY-box transcription factor 30 ameliorates ISO RGD PMID:29739711 RGD:151660333 NCBI chr10:30,918,707...30,948,415
Ensembl chr10:30,418,473...30,446,453 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase treatment
ameliorates		 ISO associated with breast cancer;
associated with nasopharynx carcinoma;		 RGD PMID:15753384 PMID:27078847 RGD:1581400, RGD:150521726 NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Tes testin LIM domain protein ameliorates ISO associated with breast cancer;
associated with stomach cancer;		 RGD PMID:22957844 PMID:30728082 RGD:597621668, RGD:597621672 NCBI chr 4:46,331,257...46,369,782
Ensembl chr 4:45,365,285...45,403,829 		JBrowse link
Lung Neoplasms term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:17902193 PMID:19180532 NCBI chr 4:156,570,163...156,619,870
Ensembl chr 4:154,897,877...154,947,786 		JBrowse link
G Ace angiotensin I converting enzyme ISO CTD Direct Evidence: marker/mechanism CTD PMID:21552421 NCBI chr10:91,410,129...91,430,246
Ensembl chr10:90,910,316...90,931,131 		JBrowse link
G Acsm1 acyl-CoA synthetase medium-chain family member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17114358 NCBI chr 1:183,417,052...183,451,897
Ensembl chr 1:173,984,672...174,025,495 		JBrowse link
G Actb actin, beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:23692979 NCBI chr12:16,776,664...16,779,634
Ensembl chr12:11,663,109...11,672,877 		JBrowse link
G Ada adenosine deaminase ISO CTD Direct Evidence: marker/mechanism CTD PMID:2305558 NCBI chr 3:172,818,174...172,842,283
Ensembl chr 3:152,398,747...152,447,088 		JBrowse link
G Adam28 ADAM metallopeptidase domain 28 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20544843 NCBI chr15:50,184,286...50,250,605
Ensembl chr15:42,944,467...43,840,672 		JBrowse link
G Ager advanced glycosylation end product-specific receptor ISO GAD PMID:15118671 RGD:1331525 NCBI chr20:4,152,758...4,155,956
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:12511591 PMID:21911043 PMID:22619562 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type ISO RGD PMID:7511046 RGD:2313872 NCBI chr10:55,456,923...55,469,239
Ensembl chr10:54,958,271...54,970,542 		JBrowse link
G Alx4 ALX homeobox 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24037716 NCBI chr 3:100,067,052...100,103,624
Ensembl chr 3:79,611,719...79,648,260 		JBrowse link
G Ank3 ankyrin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27935865 NCBI chr20:18,601,307...19,224,790
Ensembl chr20:18,602,786...19,086,300 		JBrowse link
G Anxa2 annexin A2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20682992 NCBI chr 8:78,986,252...79,022,638
Ensembl chr 8:70,105,253...70,141,658 		JBrowse link
G Apc APC regulator of WNT signaling pathway ISO CTD Direct Evidence: marker/mechanism CTD PMID:18337602 NCBI chr18:26,138,382...26,196,021
Ensembl chr18:25,864,222...25,922,696 		JBrowse link
G Apoa1 apolipoprotein A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19180532 NCBI chr 8:55,423,945...55,425,729
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G Apoc3 apolipoprotein C3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19180532 NCBI chr 8:55,428,172...55,430,352
Ensembl chr 8:46,531,478...46,533,583 		JBrowse link
G Apoe apolipoprotein E ISO CTD Direct Evidence: marker/mechanism CTD PMID:19180532 PMID:20430468 NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Ar androgen receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:30008631 NCBI chr  X:67,135,317...67,304,476
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Arhgef5 Rho guanine nucleotide exchange factor 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29054765 NCBI chr 4:73,087,240...73,112,311
Ensembl chr 4:72,087,247...72,111,254 		JBrowse link
G As3mt arsenite methyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:36399430 NCBI chr 1:245,595,939...245,628,921
Ensembl chr 1:245,596,108...245,627,872 		JBrowse link
G Atg101 autophagy related 101 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27935865 NCBI chr 7:134,277,223...134,286,387
Ensembl chr 7:132,398,483...132,407,633 		JBrowse link
G Atox1 antioxidant 1 copper chaperone ISO CTD Direct Evidence: marker/mechanism CTD PMID:23624903 NCBI chr10:40,065,525...40,080,627
Ensembl chr10:39,564,857...39,579,950 		JBrowse link
G Avpi1 arginine vasopressin-induced 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27935865 NCBI chr 1:240,930,236...240,936,154
Ensembl chr 1:240,930,236...240,936,154 		JBrowse link
G Azgp1 alpha-2-glycoprotein 1, zinc-binding ISO CTD Direct Evidence: marker/mechanism CTD PMID:18978557 NCBI chr12:22,044,685...22,051,248
Ensembl chr12:16,931,024...16,939,091 		JBrowse link
G Bap1 BRCA1 associated deubiquitinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26719535 NCBI chr16:6,453,126...6,461,952
Ensembl chr16:6,446,709...6,455,535 		JBrowse link
G Bcl2l1 Bcl2-like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16007126 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479 		JBrowse link
G Becn1 beclin 1 ISO CTD Direct Evidence: therapeutic CTD PMID:22481206 PMID:23790316 NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Bhlhe41 basic helix-loop-helix family, member e41 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27935865 NCBI chr 4:180,565,003...180,569,415
Ensembl chr 4:178,834,271...178,838,468 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:15981204 PMID:16108013 NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase ISO CTD Direct Evidence: marker/mechanism CTD NCBI chr 4:69,329,772...69,476,931
Ensembl chr 4:68,384,649...68,510,463 		JBrowse link
G Brca2 BRCA2, DNA repair associated ISO CTD Direct Evidence: marker/mechanism CTD PMID:24880342 NCBI chr12:4,895,092...4,939,340
Ensembl chr12:59,819...100,567 		JBrowse link
G Calml3 calmodulin-like 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27935865 NCBI chr17:71,329,438...71,333,068
Ensembl chr17:66,419,882...66,423,175 		JBrowse link
G Car12 carbonic anhydrase 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27935865 NCBI chr 8:76,169,723...76,225,465
Ensembl chr 8:67,274,359...67,330,440 		JBrowse link
G Casp7 caspase 7 disease_progression ISO RGD PMID:23979166 RGD:13209143 NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:255,437,172...255,476,729 		JBrowse link
G Casp8 caspase 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17450141 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Cav1 caveolin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29247004 NCBI chr 4:46,606,538...46,639,616
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Cbr2 carbonyl reductase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18597497 NCBI chr10:106,508,964...106,511,614
Ensembl chr10:105,991,589...106,013,001 		JBrowse link
G Cbx5 chromobox 5 ISO RGD PMID:22900142 RGD:9586743 NCBI chr 7:136,203,827...136,254,575
Ensembl chr 7:134,331,335...134,375,022 		JBrowse link
G Cbx7 chromobox 7 ISO protein:decreased expression:lung (human) RGD PMID:22214847 PMID:22214847 RGD:9587356, RGD:9587356 NCBI chr 7:113,341,030...113,358,716
Ensembl chr 7:111,460,656...111,477,973 		JBrowse link
G Ccn1 cellular communication network factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27935865 NCBI chr 2:237,222,730...237,225,689
Ensembl chr 2:234,562,408...234,565,484 		JBrowse link
G Ccn2 cellular communication network factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21552421 NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Ccnd1 cyclin D1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11307925 PMID:16289808 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccng1 cyclin G1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16289808 NCBI chr10:25,678,503...25,684,876
Ensembl chr10:25,176,234...25,181,641 		JBrowse link
G Cd274 CD274 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:27692344 PMID:34166680 NCBI chr 1:236,526,215...236,549,956
Ensembl chr 1:227,116,649...227,134,450 		JBrowse link
G Cdc5l cell division cycle 5-like ISO mRNA:increased expression:lung (mouse) RGD PMID:14647414 RGD:10047051 NCBI chr 9:23,062,397...23,100,901
Ensembl chr 9:15,564,767...15,603,450 		JBrowse link
G Cdh13 cadherin 13 IDA
ISO		 associated with Inflammation;DNA:hypermethylation:promoter
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:18337602 PMID:17971904 PMID:9737784 RGD:2293546, RGD:734736 NCBI chr19:63,258,251...64,296,122
Ensembl chr19:46,349,430...47,387,459 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:12466968 PMID:18508827 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:12466968 PMID:16391232 PMID:20512841 NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C ISO CTD Direct Evidence: marker/mechanism CTD PMID:20512841 PMID:21552421 NCBI chr 1:208,084,801...208,087,680
Ensembl chr 1:198,655,407...198,658,048 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A IDA
ISO		 DNA:hypermethylation:promoter
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:11872642 PMID:12115568 PMID:18337602 PMID:20135361 PMID:11872642 More... RGD:1298567, RGD:7248761 NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21552421 NCBI chr 1:90,171,401...90,187,810
Ensembl chr 1:81,043,595...81,059,992 		JBrowse link
G Ces1d carboxylesterase 1D ISO CTD Direct Evidence: marker/mechanism CTD PMID:17114358 PMID:17311802 NCBI chr19:30,046,494...30,085,039
Ensembl chr19:13,796,623...13,912,035 		JBrowse link
G Chd4 chromodomain helicase DNA binding protein 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30008631 NCBI chr 4:159,584,623...159,617,867
Ensembl chr 4:157,899,391...157,931,541 		JBrowse link
G Chek2 checkpoint kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24880342 NCBI chr12:51,448,838...51,481,159
Ensembl chr12:45,788,827...45,821,286 		JBrowse link
G Chrna2 cholinergic receptor nicotinic alpha 2 subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:28604730 NCBI chr15:44,517,862...44,534,144
Ensembl chr15:40,342,317...40,358,601 		JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:18385738 NCBI chr 8:64,297,755...64,311,251
Ensembl chr 8:55,401,702...55,415,165 		JBrowse link
G Chrna5 cholinergic receptor nicotinic alpha 5 subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:18385738 NCBI chr 8:64,265,879...64,294,233
Ensembl chr 8:55,369,794...55,398,146 		JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:24089524 NCBI chr 1:126,123,425...126,249,181
Ensembl chr 1:116,714,711...116,837,240 		JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:18385738 NCBI chr 8:64,312,644...64,333,319
Ensembl chr 8:55,418,313...55,437,027 		JBrowse link
G Chst15 carbohydrate sulfotransferase 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27935865 NCBI chr 1:196,458,978...196,540,088
Ensembl chr 1:187,028,970...187,107,707 		JBrowse link
G Clca2 chloride channel accessory 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27935865 NCBI chr 2:236,655,419...236,682,669
Ensembl chr 2:233,995,078...234,022,199 		JBrowse link
G Clptm1l CLPTM1-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:18978787 PMID:19151717 PMID:23433592 PMID:24366883 NCBI chr 1:31,496,094...31,512,148
Ensembl chr 1:29,667,545...29,683,530 		JBrowse link
G Cltb clathrin, light chain B ISO CTD Direct Evidence: marker/mechanism CTD PMID:27935865 NCBI chr17:10,006,416...10,024,278
Ensembl chr17:10,001,513...10,019,169 		JBrowse link
G Col6a1 collagen type VI alpha 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:23692979 NCBI chr20:11,905,690...11,924,111
Ensembl chr20:11,905,957...11,924,597 		JBrowse link
G Cox17 cytochrome c oxidase copper chaperone COX17 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23624903 NCBI chr11:75,906,245...75,912,036 JBrowse link
G Cpe carboxypeptidase E ISO CTD Direct Evidence: marker/mechanism CTD PMID:27935865 NCBI chr16:29,796,707...29,908,647
Ensembl chr16:25,030,276...25,142,233 		JBrowse link
G Crp C-reactive protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:17114654 NCBI chr13:87,694,062...87,695,978
Ensembl chr13:85,124,977...85,175,178 		JBrowse link
G Ctnnb1 catenin beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18372914 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Cwh43 cell wall biogenesis 43 C-terminal homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:27935865 NCBI chr14:35,108,328...35,154,578
Ensembl chr14:34,754,289...34,800,814 		JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 ISO CTD Direct Evidence: therapeutic CTD PMID:20562917 NCBI chr17:8,323,150...8,331,176
Ensembl chr17:8,317,933...8,324,839 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22072123 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11376689 NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22797725 NCBI chr 3:179,694,647...179,709,083
Ensembl chr 3:159,275,947...159,290,383 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:1673675 PMID:17093202 NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Dab2ip DAB2 interacting protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:22046421 NCBI chr 3:39,312,745...39,483,730
Ensembl chr 3:18,915,290...19,086,280 		JBrowse link
G Dapk1 death associated protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15172992 NCBI chr17:3,935,826...4,096,858
Ensembl chr17:3,930,213...4,090,991 		JBrowse link
G Ddr1 discoidin domain receptor tyrosine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21552421 NCBI chr20:3,047,269...3,069,277
Ensembl chr20:3,044,320...3,064,468 		JBrowse link
G Dnai7 dynein axonemal intermediate chain 7 susceptibility ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:15064703 PMID:16862160 RGD:11340955 NCBI chr 4:178,143,499...178,179,871
Ensembl chr 4:178,143,500...178,179,980 		JBrowse link
G Dnase1l3 deoxyribonuclease 1L3 ISO CTD Direct Evidence: therapeutic CTD PMID:21720004 NCBI chr15:19,351,683...19,378,536
Ensembl chr15:16,922,335...16,948,317 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:26192916 NCBI chr 6:32,507,316...32,621,678
Ensembl chr 6:26,822,609...26,896,687 		JBrowse link
G Dok1 docking protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20139980 NCBI chr 4:115,537,453...115,540,464
Ensembl chr 4:115,537,462...115,540,465 		JBrowse link
G Dok2 docking protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20139980 NCBI chr15:52,237,046...52,251,091
Ensembl chr15:45,827,398...45,841,402 		JBrowse link
G Dok3 docking protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20139980 NCBI chr17:9,109,633...9,115,188
Ensembl chr17:9,109,597...9,115,188 		JBrowse link
G Dpyd dihydropyrimidine dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19020767 NCBI chr 2:209,293,902...210,159,777
Ensembl chr 2:206,609,122...207,474,982 		JBrowse link
G Eaf2 ELL associated factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20564326 NCBI chr11:77,465,585...77,509,993
Ensembl chr11:63,960,200...64,004,610 		JBrowse link
G Eef2 eukaryotic translation elongation factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21554491 NCBI chr 7:9,183,836...9,196,255
Ensembl chr 7:8,533,116...8,559,183 		JBrowse link
G Efemp1 EGF containing fibulin extracellular matrix protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17671114 NCBI chr14:106,811,769...106,890,961
Ensembl chr14:102,610,908...102,690,018 		JBrowse link
G Efnb2 ephrin B2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27935865 NCBI chr16:87,485,215...87,529,224
Ensembl chr16:80,783,417...80,824,391 		JBrowse link
G Egfr epidermal growth factor receptor ISO protein:increased expression:tumor (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:18927287 PMID:19336973 PMID:20934974 PMID:21541241 PMID:23523951 More... RGD:5131628 NCBI chr14:95,378,626...95,551,358
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Egr1 early growth response 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27935865 NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20940408 NCBI chr20:3,924,263...3,941,238
Ensembl chr20:3,919,624...3,941,547 		JBrowse link
G Emx2 empty spiracles homeobox 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20697358 NCBI chr 1:258,626,584...258,633,594
Ensembl chr 1:258,626,584...258,633,594 		JBrowse link
G Ephx1 epoxide hydrolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17114358 PMID:17311802 NCBI chr13:95,246,079...95,275,852
Ensembl chr13:92,714,315...92,790,235 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12483526 NCBI chr10:83,907,491...83,931,365
Ensembl chr10:83,411,313...83,435,078 		JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12483526 NCBI chr 7:1,579,079...1,600,379
Ensembl chr 7:996,225...1,015,525 		JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:30453383 NCBI chr 1:88,099,308...88,135,966
Ensembl chr 1:78,996,390...79,007,963 		JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit susceptibility ISO DNA:haplotype:cds:p.K751Q(human) GAD
RGD		 PMID:15118671 PMID:17498557 RGD:1331525, RGD:12880386 NCBI chr 1:88,161,342...88,175,102
Ensembl chr 1:79,033,326...79,047,102 		JBrowse link
G Ercc3 ERCC excision repair 3, TFIIH core complex helicase subunit susceptibility ISO DNA:snps, haplotype:introns:c.43-61A>G, c.1151-2708A>G, (rs2271026, rs4150441) (human) RGD PMID:16835333 RGD:13207447 NCBI chr18:24,157,831...24,188,543
Ensembl chr18:23,883,580...23,914,329 		JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor susceptibility ISO CTD Direct Evidence: marker/mechanism
DNA:SNPs: :rs3793784, rs12571445 (human)		 CTD
RGD		 PMID:17854076 PMID:18789574 RGD:11567231 NCBI chr16:7,771,311...7,841,895
Ensembl chr16:7,765,013...7,835,587 		JBrowse link
G Ergic3 ERGIC and golgi 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27588471 NCBI chr 3:164,985,108...164,994,897
Ensembl chr 3:144,525,092...144,534,813 		JBrowse link
G Esr1 estrogen receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11872642 PMID:17077188 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Fas Fas cell surface death receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:26192916 NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Faslg Fas ligand ISO CTD Direct Evidence: marker/mechanism CTD NCBI chr13:76,680,885...76,706,042
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Fen1 flap structure-specific endonuclease 1 ISO DNA:missense mutation:cds:p.E160D
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:28371273 PMID:17589521 RGD:6484213 NCBI chr 1:216,270,016...216,274,873
Ensembl chr 1:206,844,884...206,850,003 		JBrowse link
G Fgf9 fibroblast growth factor 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20464547 NCBI chr15:36,325,552...36,369,995
Ensembl chr15:32,210,074...32,253,309 		JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21936542 NCBI chr16:73,194,631...73,249,855
Ensembl chr16:66,494,042...66,547,350 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17311802 NCBI chr 1:194,175,703...194,280,914
Ensembl chr 1:184,745,420...184,850,626 		JBrowse link
G Fhit fragile histidine triad diadenosine triphosphatase ISO CTD Direct Evidence: marker/mechanism CTD PMID:10959838 PMID:16061637 NCBI chr15:16,365,401...17,872,901
Ensembl chr15:13,934,995...15,442,340 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:16289808 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:27935865 NCBI chr 1:88,082,324...88,089,506
Ensembl chr 1:78,954,115...78,961,465 		JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:27935865 NCBI chr 6:30,017,952...30,039,269
Ensembl chr 6:24,300,956...24,320,034 		JBrowse link
G Foxm1 forkhead box M1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16489016 PMID:23255470 NCBI chr 4:163,325,628...163,338,100
Ensembl chr 4:161,638,816...161,650,684 		JBrowse link
G Foxp3 forkhead box P3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34166680 NCBI chr  X:17,580,380...17,601,181
Ensembl chr  X:14,908,494...14,923,838 		JBrowse link
G Fubp1 far upstream element binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35915169 NCBI chr 2:243,819,529...243,846,544
Ensembl chr 2:241,159,512...241,186,602 		JBrowse link
G Gast gastrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:11208460 NCBI chr10:85,765,216...85,767,881
Ensembl chr10:85,264,832...85,267,496 		JBrowse link
G Gata6 GATA binding protein 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16271038 NCBI chr18:2,460,909...2,492,322
Ensembl chr18:2,188,121...2,219,532 		JBrowse link
G Gc GC, vitamin D binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:17902193 NCBI chr14:18,916,255...18,951,670
Ensembl chr14:18,632,135...18,667,567 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:27935865 NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Ggt5 gamma-glutamyltransferase 5 IEP
ISO		 mRNA:increased expression:lung
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:9374738 PMID:9374738 RGD:69846 NCBI chr20:13,042,694...13,070,960
Ensembl chr20:13,043,257...13,071,450 		JBrowse link
G Gja1 gap junction protein, alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15166089 PMID:16926031 NCBI chr20:36,302,490...36,315,010
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Gjb1 gap junction protein, beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15492231 PMID:16926031 NCBI chr  X:70,541,845...70,549,776
Ensembl chr  X:66,501,820...66,509,925 		JBrowse link
G Gpx1 glutathione peroxidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11103801 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Gpx3 glutathione peroxidase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19180532 PMID:21552421 NCBI chr10:39,529,335...39,537,406
Ensembl chr10:39,028,570...39,037,035 		JBrowse link
G Grb7 growth factor receptor bound protein 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21552421 NCBI chr10:83,936,538...83,949,344
Ensembl chr10:83,444,004...83,453,052 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17114358 PMID:17311802 PMID:22072123 PMID:24852519 PMID:15118671 RGD:1331525 NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Gstm2 glutathione S-transferase mu 2 ISO GAD PMID:15118671 RGD:1331525 NCBI chr 2:198,312,179...198,316,962
Ensembl chr 2:195,544,426...195,628,961 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17909032 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Gstt1 glutathione S-transferase theta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17000715 PMID:24852519 NCBI chr20:12,856,068...12,873,020
Ensembl chr20:12,856,669...12,873,585 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17804716 NCBI chr11:84,210,632...84,213,045
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17804716 NCBI chr 2:95,003,935...95,006,457
Ensembl chr 2:93,095,498...93,100,312 		JBrowse link
G Hilpda hypoxia inducible lipid droplet-associated ISO CTD Direct Evidence: marker/mechanism CTD PMID:27935865 NCBI chr 4:58,836,463...58,839,423
Ensembl chr 4:57,871,110...57,874,557 		JBrowse link
G Hmox1 heme oxygenase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15688187 PMID:18508827 PMID:31227482 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hras HRas proto-oncogene, GTPase ISO CTD Direct Evidence: marker/mechanism CTD PMID:10779650 PMID:11307925 PMID:11552296 PMID:12765245 PMID:15902970 NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:196,296,263...196,300,615 		JBrowse link
G Htra1 HtrA serine peptidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27935865 NCBI chr 1:194,928,069...194,977,619
Ensembl chr 1:185,497,735...185,547,379 		JBrowse link
G Id3 inhibitor of DNA binding 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21552421 NCBI chr 5:153,656,253...153,657,860
Ensembl chr 5:148,372,762...148,374,349 		JBrowse link
G Ids iduronate 2-sulfatase ISO CTD Direct Evidence: marker/mechanism CTD PMID:27935865 NCBI chr  X:154,070,781...154,093,681
Ensembl chr  X:149,025,976...149,046,663 		JBrowse link
G Ier2 immediate early response 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27935865 NCBI chr19:40,399,373...40,400,897
Ensembl chr19:23,494,184...23,499,211 		JBrowse link
G Ifng interferon gamma ISO CTD Direct Evidence: therapeutic CTD PMID:7614408 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Igbp1 immunoglobulin binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21339737 NCBI chr  X:69,622,925...69,645,167
Ensembl chr  X:65,582,821...65,606,049 		JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:17114358 NCBI chr  X:157,358,279...157,397,563
Ensembl chr  X:152,216,596...152,239,499 		JBrowse link
G Il10 interleukin 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14587096 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il1b interleukin 1 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:22369883 PMID:28212736 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1r2 interleukin 1 receptor type 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27935865 NCBI chr 9:49,879,928...49,920,374
Ensembl chr 9:42,384,433...42,424,725 		JBrowse link
G Il2 interleukin 2 ISO CTD Direct Evidence: therapeutic CTD PMID:7614408 PMID:18298334 PMID:18625569 NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il24 interleukin 24 ISO CTD Direct Evidence: therapeutic CTD PMID:12830052 PMID:15713900 NCBI chr13:44,905,362...44,910,760
Ensembl chr13:42,353,090...42,358,487 		JBrowse link
G Il6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26372664 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Iqsec1 IQ motif and Sec7 domain ArfGEF 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27935865 NCBI chr 4:124,725,917...125,045,351
Ensembl chr 4:123,168,719...123,488,172 		JBrowse link
G Irf1 interferon regulatory factor 1 ISO CTD Direct Evidence: marker/mechanism CTD NCBI chr10:38,417,935...38,424,946
Ensembl chr10:37,916,670...37,924,166 		JBrowse link
G Irf4 interferon regulatory factor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35915169 NCBI chr17:33,930,460...33,948,842
Ensembl chr17:33,721,811...33,740,070 		JBrowse link
G Jag1 jagged canonical Notch ligand 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17804716 NCBI chr 3:144,859,453...144,894,883
Ensembl chr 3:124,406,794...124,442,209 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:20716630 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:16289808 PMID:27935865 NCBI chr19:40,081,126...40,082,910
Ensembl chr19:23,176,294...23,178,035 		JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:27935865 NCBI chr16:18,768,093...18,769,771
Ensembl chr16:18,734,122...18,735,799 		JBrowse link
G Kdr kinase insert domain receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:35917945 NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,217,871...32,261,018 		JBrowse link
G Kras KRAS proto-oncogene, GTPase ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:7614698 PMID:7750092 PMID:8508514 PMID:8597069 PMID:8761429 More... RGD:11568678 NCBI chr 4:179,916,255...179,949,613 JBrowse link
G Lect2 leukocyte cell-derived chemotaxin 2 ISO CTD Direct Evidence: therapeutic CTD PMID:30453282 NCBI chr17:8,050,034...8,056,256
Ensembl chr17:8,044,759...8,050,983 		JBrowse link
G Lmntd1 lamin tail domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15064703 NCBI chr 4:178,354,302...178,588,483
Ensembl chr 4:178,354,137...178,588,477 		JBrowse link
G LOC120095955 mucin-12-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:29054765 NCBI chr12:19,486,041...19,493,995 JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 ISO RGD PMID:24233520 RGD:7495808 NCBI chr10:46,107,639...46,128,986
Ensembl chr10:45,607,163...45,629,492 		JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21317887 NCBI chr12:7,389,032...7,398,377
Ensembl chr12:2,591,219...2,604,222 		JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 ISO CTD Direct Evidence: marker/mechanism CTD NCBI chr17:58,078,175...58,098,455
Ensembl chr17:53,383,131...53,403,216 		JBrowse link
G Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27935865 NCBI chr 9:49,696,573...49,822,353
Ensembl chr 9:42,200,278...42,326,698 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11884234 PMID:12376484 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 ameliorates ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:17468755 PMID:31969449 RGD:151665505 NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,749,670...6,810,589 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11884234 PMID:12083368 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Marcks myristoylated alanine rich protein kinase C substrate ISO CTD Direct Evidence: marker/mechanism CTD PMID:27935865 NCBI chr20:42,240,185...42,245,882
Ensembl chr20:40,685,315...40,691,012 		JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member ISO CTD Direct Evidence: marker/mechanism CTD PMID:19903766 PMID:27935865 NCBI chr 2:185,884,840...185,912,532
Ensembl chr 2:183,219,220...183,222,303 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20934974 NCBI chr 4:46,756,823...46,864,041
Ensembl chr 4:45,790,791...45,897,876 		JBrowse link
G Mir10a microRNA 10a ISO CTD Direct Evidence: marker/mechanism CTD PMID:25105010 NCBI chr10:81,779,709...81,779,818
Ensembl chr10:81,283,171...81,283,280 		JBrowse link
G Mir127 microRNA 127 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25105010 NCBI chr 6:134,328,454...134,328,550
Ensembl chr 6:128,546,215...128,546,311 		JBrowse link
G Mir136 microRNA 136 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25105010 NCBI chr 6:134,331,335...134,331,416
Ensembl chr 6:128,549,096...128,549,177 		JBrowse link
G Mir146a microRNA 146a ISO CTD Direct Evidence: marker/mechanism CTD PMID:25105010 NCBI chr10:28,349,996...28,350,090
Ensembl chr10:27,848,516...27,848,610 		JBrowse link
G Mir154 microRNA 154 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25105010 NCBI chr 6:134,574,352...134,574,435
Ensembl chr 6:128,752,947...128,753,030 		JBrowse link
G Mir155 microRNA 155 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25105010 PMID:27692344 NCBI chr11:37,261,114...37,261,178
Ensembl chr11:23,774,654...23,774,718 		JBrowse link
G Mir193a microRNA 193a ISO CTD Direct Evidence: marker/mechanism CTD PMID:25105010 NCBI chr10:65,170,306...65,170,417
Ensembl chr10:64,672,343...64,672,454 		JBrowse link
G Mir1a-1 microRNA 1a-1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23761296 NCBI chr 3:167,487,117...167,487,201
Ensembl chr 3:167,487,117...167,487,201 		JBrowse link
G Mir21 microRNA 21 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27323401 NCBI chr10:71,902,600...71,902,691
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mir222 microRNA 222 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25105010 NCBI chr  X:6,022,621...6,022,723
Ensembl chr  X:3,428,904...3,429,006 		JBrowse link
G Mir224 microRNA 224 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25105010 NCBI chr  X:155,107,130...155,107,211
Ensembl chr  X:150,065,088...150,065,169 		JBrowse link
G Mir30a microRNA 30a ISO CTD Direct Evidence: marker/mechanism CTD PMID:25105010 NCBI chr 9:33,233,941...33,234,011
Ensembl chr 9:25,737,600...25,737,670 		JBrowse link
G Mir31 microRNA 31 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20237410 NCBI chr 5:108,714,849...108,714,954 JBrowse link
G Mir34b microRNA 34b ISO CTD Direct Evidence: marker/mechanism CTD PMID:21339737 PMID:25105010 NCBI chr 8:60,306,609...60,306,692
Ensembl chr 8:51,410,244...51,410,327 		JBrowse link
G Mir34c microRNA 34c ISO CTD Direct Evidence: marker/mechanism CTD PMID:25105010 NCBI chr 8:60,306,091...60,306,167
Ensembl chr 8:51,409,726...51,409,802 		JBrowse link
G Mir370 microRNA 370 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25105010 NCBI chr 6:128,572,257...128,572,335
Ensembl chr 6:128,572,257...128,572,335 		JBrowse link
G Mir409 microRNA 409 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25105010 NCBI chr 6:134,579,185...134,579,261
Ensembl chr 6:128,757,779...128,757,858 		JBrowse link
G Mir410 microRNA 410 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25105010 NCBI chr 6:134,579,763...134,579,838
Ensembl chr 6:128,758,354...128,758,434 		JBrowse link
G Mir487b microRNA 487b ISO CTD Direct Evidence: marker/mechanism CTD PMID:25105010 NCBI chr 6:134,562,890...134,562,971
Ensembl chr 6:128,741,485...128,741,566 		JBrowse link
G Mir494 microRNA 494 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25105010 NCBI chr 6:134,550,115...134,550,197
Ensembl chr 6:128,728,709...128,728,793 		JBrowse link
G Mir98 microRNA 98 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27270317 NCBI chr  X:24,460,648...24,460,755
Ensembl chr  X:20,981,235...20,981,342 		JBrowse link
G Mirlet7bhg Mirlet7b host gene ISO CTD Direct Evidence: marker/mechanism CTD PMID:26199339
G Mmp1 matrix metallopeptidase 1 no_association ISO DNA:insertion:promoter:g.-1607insG (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:23548910 PMID:19843588 RGD:7207056 NCBI chr 8:12,943,453...12,963,966
Ensembl chr 8:4,658,588...4,679,097 		JBrowse link
G Mmp10 matrix metallopeptidase 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22022614 NCBI chr 8:12,974,707...12,982,613
Ensembl chr 8:4,689,840...4,697,748 		JBrowse link
G Mmp7 matrix metallopeptidase 7 ISO mRNA:increased expression:lung RGD PMID:19596921 RGD:5129528 NCBI chr 8:13,133,043...13,140,761
Ensembl chr 8:4,848,186...4,855,902 		JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO Pulmonary Sclerosing Hemangioma; mRNA, protein:increased expression:lung
associated with lung disease; protein:decreased expression:pleural fluid		 RGD PMID:17914564 PMID:20216542 RGD:5130173, RGD:5129491 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mpo myeloperoxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:12111688 NCBI chr10:73,092,124...73,102,057
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Mpp1 MAGUK p55 scaffold protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21552421
G Mthfr methylenetetrahydrofolate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:17389614 NCBI chr 5:163,748,346...163,768,141
Ensembl chr 5:158,465,296...158,483,797 		JBrowse link
G Mtor mechanistic target of rapamycin kinase treatment ISO RGD PMID:19966866 RGD:11568678 NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Muc16 mucin 16, cell surface associated ISO CTD Direct Evidence: marker/mechanism CTD PMID:29552305 NCBI chr 8:24,440,840...24,644,494 JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:16289808 PMID:28191284 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Myo18b myosin XVIIIb ISO CTD Direct Evidence: marker/mechanism CTD PMID:29054765 NCBI chr12:49,421,062...49,614,127
Ensembl chr12:43,747,010...43,953,695 		JBrowse link
G Nat1 N-acetyltransferase 1 susceptibility ISO DNA:polymorphism: : RGD PMID:9626964 RGD:5131866 NCBI chr16:26,984,882...27,005,194
Ensembl chr16:22,208,194...22,238,520 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31227482 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfya nuclear transcription factor Y subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:16271038 NCBI chr 9:20,085,067...20,111,521
Ensembl chr 9:12,586,259...12,613,898 		JBrowse link
G Nos2 nitric oxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12460898 PMID:22369883 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Notch2 notch receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17804716 NCBI chr 2:188,299,336...188,432,823
Ensembl chr 2:185,610,589...185,744,088 		JBrowse link
G Notch3 notch receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17804716 NCBI chr 7:11,783,550...11,834,585
Ensembl chr 7:11,133,706...11,184,025 		JBrowse link
G Nppa natriuretic peptide A ISO CTD Direct Evidence: therapeutic CTD PMID:18717826 NCBI chr 5:163,712,184...163,713,493
Ensembl chr 5:158,429,042...158,430,351 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 susceptibility ISO DNA:polymorphism: : 609C>T (human)
DNA:SNP: :609C>T (human)
DNA:polymorphism:cds:		 RGD PMID:15781212 PMID:12018106 PMID:18798003 RGD:5134987, RGD:10769350, RGD:5134963 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nrg1 neuregulin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28604730 NCBI chr16:65,954,084...67,007,484
Ensembl chr16:59,250,854...60,296,884 		JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:17441966 PMID:19336973 NCBI chr 4:148,030,237...148,037,599
Ensembl chr 4:146,474,750...146,484,766 		JBrowse link
G Pcna proliferating cell nuclear antigen ISO CTD Direct Evidence: marker/mechanism CTD PMID:11884234 NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Pdcd1 programmed cell death 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34166680 NCBI chr 9:101,866,124...101,879,278
Ensembl chr 9:94,418,791...94,431,937 		JBrowse link
G Pdcd4 programmed cell death 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27323401 NCBI chr 1:262,912,659...262,949,581
Ensembl chr 1:252,921,392...252,944,275 		JBrowse link
G Pdgfrb platelet derived growth factor receptor beta ISO RGD PMID:17050049 RGD:2292176 NCBI chr18:56,770,348...56,809,228
Ensembl chr18:54,499,964...54,538,843 		JBrowse link
G Pdlim4 PDZ and LIM domain 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27935865 NCBI chr10:38,699,444...38,713,696
Ensembl chr10:38,198,689...38,212,938 		JBrowse link
G Pggt1b protein geranylgeranyltransferase type I subunit beta ISO CTD Direct Evidence: therapeutic CTD PMID:22028818 NCBI chr18:41,138,536...41,182,145
Ensembl chr18:38,952,914...38,995,503 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:16847462 RGD:2290476 NCBI chr 2:117,103,643...117,177,411
Ensembl chr 2:115,174,984...115,249,032 		JBrowse link
G Plau plasminogen activator, urokinase severity ISO protein:increased expression:tumor, cytoplasm (human) RGD PMID:2054790 RGD:7241261 NCBI chr15:3,505,485...3,511,987
Ensembl chr15:3,456,232...3,462,775 		JBrowse link
G Pon1 paraoxonase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16323636 NCBI chr 4:34,261,312...34,292,327
Ensembl chr 4:33,294,722...33,321,360 		JBrowse link
G Ppbp pro-platelet basic protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:27935865 NCBI chr14:17,586,495...17,587,299
Ensembl chr14:17,302,326...17,303,130 		JBrowse link
G Ppp1r9b protein phosphatase 1, regulatory subunit 9B severity ISO protein:decreased expression:lung (human) RGD PMID:21598252 RGD:10043809 NCBI chr10:80,434,888...80,450,919
Ensembl chr10:79,938,066...79,954,083 		JBrowse link
G Ppp2r1b protein phosphatase 2 scaffold subunit A beta ISO CTD Direct Evidence: marker/mechanism CTD NCBI chr 8:60,092,540...60,125,512
Ensembl chr 8:51,186,717...51,228,485 		JBrowse link
G Prdx1 peroxiredoxin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22537621 NCBI chr 5:135,383,906...135,399,504
Ensembl chr 5:130,147,204...130,162,856 		JBrowse link
G Prdx6 peroxiredoxin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23692979 NCBI chr13:76,062,082...76,072,631
Ensembl chr13:73,528,210...73,539,355 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19946270 PMID:25640678 NCBI chr 1:51,236,410...52,430,242
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Pten phosphatase and tensin homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:17909629 PMID:27980214 NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Ptgis prostaglandin I2 synthase ISO CTD Direct Evidence: therapeutic CTD PMID:11830527 NCBI chr 3:176,347,589...176,383,251
Ensembl chr 3:155,916,412...155,965,451 		JBrowse link
G Ptma prothymosin alpha ISO CTD Direct Evidence: therapeutic CTD PMID:10822126 NCBI chr 9:94,624,194...94,628,276
Ensembl chr 9:87,176,230...87,180,333 		JBrowse link
G Pycard PYD and CARD domain containing ISO CTD Direct Evidence: marker/mechanism CTD PMID:16778195 NCBI chr 1:192,032,124...192,033,419
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Rad52 RAD52 homolog, DNA repair protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:26013599 NCBI chr 4:154,778,320...154,802,002
Ensembl chr 4:153,106,062...153,128,207 		JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:11884234 NCBI chr 4:150,352,158...150,412,813
Ensembl chr 4:148,679,530...148,740,317 		JBrowse link
G Ramp2 receptor activity modifying protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17671114 NCBI chr10:86,689,148...86,690,956
Ensembl chr10:86,188,812...86,231,829 		JBrowse link
G Rarb retinoic acid receptor, beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:14656941 NCBI chr15:10,837,252...11,482,037
Ensembl chr15:8,406,492...9,051,288 		JBrowse link
G Rassf1 Ras association domain family member 1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:18337602 PMID:12222680 PMID:17325427 RGD:2291977, RGD:2291979 NCBI chr 8:117,103,665...117,114,805
Ensembl chr 8:108,225,023...108,236,164 		JBrowse link
G Rchy1 ring finger and CHY zinc finger domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28191284 NCBI chr14:16,397,533...16,413,286
Ensembl chr14:16,113,224...16,129,167 		JBrowse link
G Riox2 ribosomal oxygenase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15897898 NCBI chr11:54,327,311...54,353,989
Ensembl chr11:40,860,774...40,884,574 		JBrowse link
G Rnaset2 ribonuclease T2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28604730 NCBI chr 1:52,576,344...52,603,151
Ensembl chr 1:52,585,929...52,603,147 		JBrowse link
G Robo1 roundabout guidance receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17671114 NCBI chr11:24,067,869...25,108,694
Ensembl chr11:10,580,908...11,620,203 		JBrowse link
G Rtel1 regulator of telomere elongation helicase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28604730 NCBI chr 3:188,778,329...188,842,877
Ensembl chr 3:168,419,579...168,465,348 		JBrowse link
G Runx3 RUNX family transcription factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21552421 NCBI chr 5:152,644,270...152,702,835
Ensembl chr 5:147,360,994...147,419,156 		JBrowse link
G Scgb3a2 secretoglobin, family 3A, member 2 ISO RGD PMID:20466451 PMID:19418968 RGD:5147390, RGD:5147392 NCBI chr18:36,183,745...36,186,667
Ensembl chr18:35,932,840...35,935,762 		JBrowse link
G Secisbp2l SECIS binding protein 2-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:28604730 NCBI chr 3:133,443,023...133,489,467
Ensembl chr 3:112,991,908...113,035,884 		JBrowse link
G Selenbp1 selenium binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14991897 NCBI chr 2:185,183,022...185,193,612
Ensembl chr 2:182,493,978...182,504,594 		JBrowse link
G Selenop selenoprotein P ISO CTD Direct Evidence: marker/mechanism CTD PMID:19058871 NCBI chr 2:54,225,736...54,236,022
Ensembl chr 2:52,498,339...52,508,852 		JBrowse link
G Serpina1 serpin family A member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17902193 NCBI chr 6:128,631,101...128,653,125
Ensembl chr 6:122,866,312...122,888,339 		JBrowse link
G Serping1 serpin family G member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27935865 NCBI chr 3:90,249,410...90,259,299
Ensembl chr 3:69,842,739...69,852,034 		JBrowse link
G Sftpb surfactant protein B ISO CTD Direct Evidence: marker/mechanism CTD PMID:16570259 NCBI chr 4:105,917,495...105,926,631
Ensembl chr 4:104,359,396...104,368,436 		JBrowse link
G Sftpd surfactant protein D ISO CTD Direct Evidence: marker/mechanism CTD PMID:14522914 PMID:15136449 NCBI chr16:17,080,575...17,093,047
Ensembl chr16:17,046,483...17,059,927 		JBrowse link
G Sidt2 SID1 transmembrane family, member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27935865 NCBI chr 8:55,129,091...55,146,446
Ensembl chr 8:46,232,383...46,248,700 		JBrowse link
G Slc22a18 solute carrier family 22, member 18 ISO CTD Direct Evidence: marker/mechanism CTD NCBI chr 1:208,100,032...208,124,382
Ensembl chr 1:198,671,731...198,694,975 		JBrowse link
G Slc3a2 solute carrier family 3 member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26621329 NCBI chr 1:215,033,601...215,048,064
Ensembl chr 1:205,604,468...205,618,931 		JBrowse link
G Slc7a5 solute carrier family 7 member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26621329 NCBI chr19:66,843,808...66,872,412
Ensembl chr19:49,935,220...49,963,823 		JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22326869 PMID:25625007 NCBI chr 4:176,282,577...176,355,557
Ensembl chr 4:174,551,480...174,619,981 		JBrowse link
G Smarcc1 SWI/SNF related BAF chromatin remodeling complex subunit C1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21552421 NCBI chr 8:118,986,917...119,093,161
Ensembl chr 8:110,111,122...110,214,720 		JBrowse link
G Smc2 structural maintenance of chromosomes 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27935865 NCBI chr 5:71,592,428...71,648,636
Ensembl chr 5:66,807,011...66,853,242 		JBrowse link
G Snd1 staphylococcal nuclease and tudor domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25940438 NCBI chr 4:58,060,689...58,459,926
Ensembl chr 4:57,095,208...57,530,843 		JBrowse link
G Sox2 SRY-box transcription factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19801978 NCBI chr 2:119,465,131...119,467,542
Ensembl chr 2:117,536,929...117,539,338 		JBrowse link
G Sox30 SRY-box transcription factor 30 ISO CTD Direct Evidence: therapeutic CTD PMID:25435374 NCBI chr10:30,918,707...30,948,415
Ensembl chr10:30,418,473...30,446,453 		JBrowse link
G Sox9 SRY-box transcription factor 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27935865 NCBI chr10:98,305,744...98,311,250
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
G Spp1 secreted phosphoprotein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21552421 PMID:22481206 NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
G Spry2 sprouty RTK signaling antagonist 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15136453 NCBI chr15:89,106,809...89,111,926
Ensembl chr15:82,692,143...82,698,009 		JBrowse link
G Srsf1 serine and arginine rich splicing factor 1 ISO protein:increased expression:lung (mouse) RGD PMID:15390079 RGD:11038777 NCBI chr10:73,335,519...73,342,549
Ensembl chr10:72,839,274...72,845,336 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO CTD Direct Evidence: therapeutic CTD PMID:38101582 NCBI chr10:86,311,528...86,363,513
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A ISO CTD Direct Evidence: marker/mechanism CTD PMID:21552421 NCBI chr10:86,285,859...86,310,187
Ensembl chr10:85,785,537...85,809,866 		JBrowse link
G Stim1 stromal interaction molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27863410 NCBI chr 1:166,067,450...166,230,733
Ensembl chr 1:156,656,013...156,818,363 		JBrowse link
G Stk11 serine/threonine kinase 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17676035 NCBI chr 7:10,225,204...10,241,965
Ensembl chr 7:9,575,269...9,591,315 		JBrowse link
G Stn1 STN1 subunit of CST complex ISO CTD Direct Evidence: marker/mechanism CTD PMID:28604730 NCBI chr 1:256,336,916...256,371,143
Ensembl chr 1:246,395,613...246,429,531 		JBrowse link
G Tep1 telomerase associated protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11323394 NCBI chr15:26,519,429...26,567,073
Ensembl chr15:24,045,878...24,093,526 		JBrowse link
G Tert telomerase reverse transcriptase treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:11323394 PMID:19151717 PMID:23433592 PMID:19903903 RGD:11038656 NCBI chr 1:31,465,766...31,488,650
Ensembl chr 1:29,637,506...29,659,561 		JBrowse link
G Tfrc transferrin receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:16904380 NCBI chr11:81,668,478...81,690,318
Ensembl chr11:68,163,413...68,185,257 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:11074608 PMID:11641043 PMID:17418594 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11074608 NCBI chr 8:124,672,677...124,761,741
Ensembl chr 8:115,794,537...115,883,228 		JBrowse link
G Tlr4 toll-like receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19925653 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tlr9 toll-like receptor 9 ISO mRNA, protein:increased expression:tumor (human) RGD PMID:18763053 RGD:5130705 NCBI chr 8:115,743,407...115,747,523
Ensembl chr 8:106,864,680...106,868,796 		JBrowse link
G Tmem45a transmembrane protein 45A ISO CTD Direct Evidence: marker/mechanism CTD PMID:27935865 NCBI chr11:43,713,309...43,799,526
Ensembl chr11:43,713,782...43,799,526 		JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:14587096 PMID:22369883 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tp53 tumor protein p53 ISO
IMP		 CTD Direct Evidence: marker/mechanism|therapeutic
DNA:transitional mutations:exons:		 CTD
RGD		 PMID:8049841 PMID:11798837 PMID:16247444 PMID:16410370 PMID:17325666 More... RGD:1331525, RGD:11075092 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tp63 tumor protein p63 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20871597 PMID:21725308 NCBI chr11:88,343,647...88,554,543
Ensembl chr11:74,838,859...75,049,398 		JBrowse link
G Tp73 tumor protein p73 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28212736 NCBI chr 5:169,903,801...169,988,075
Ensembl chr 5:164,621,377...164,681,128 		JBrowse link
G Tsc1 TSC complex subunit 1 ISO RGD PMID:19966866 RGD:11568678 NCBI chr 3:32,367,434...32,416,565
Ensembl chr 3:11,979,729...12,015,674 		JBrowse link
G Tsc2 TSC complex subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30008631 NCBI chr10:14,125,679...14,160,317
Ensembl chr10:13,621,136...13,655,951 		JBrowse link
G Tshr thyroid stimulating hormone receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:9062474 NCBI chr 6:116,072,321...116,206,009
Ensembl chr 6:110,341,581...110,474,538 		JBrowse link
G Ttr transthyretin ISO CTD Direct Evidence: marker/mechanism CTD PMID:17902193 PMID:19180532 NCBI chr18:12,216,684...12,225,972
Ensembl chr18:11,943,789...11,951,008 		JBrowse link
G Tyms thymidylate synthetase ISO CTD Direct Evidence: marker/mechanism CTD PMID:18281538 PMID:19020767 NCBI chr 9:120,760,057...120,776,149
Ensembl chr 9:113,313,452...113,329,536 		JBrowse link
G Tyrp1 tyrosinase-related protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21552421 NCBI chr 5:100,327,111...100,345,657
Ensembl chr 5:95,280,982...95,299,516 		JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17416778 NCBI chr14:21,378,882...21,390,631
Ensembl chr14:21,024,006...21,035,986 		JBrowse link
G Usp18 ubiquitin specific peptidase 18 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27980214 NCBI chr 4:156,143,770...156,171,292
Ensembl chr 4:154,471,592...154,499,144 		JBrowse link
G Vhl von Hippel-Lindau tumor suppressor ISO CTD Direct Evidence: marker/mechanism CTD PMID:16061637 NCBI chr 4:148,328,099...148,334,992
Ensembl chr 4:146,772,468...146,779,377 		JBrowse link
G Wnt5a Wnt family member 5A ISO CTD Direct Evidence: marker/mechanism CTD PMID:23349696 NCBI chr16:3,702,300...3,724,860
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
G Wt1 WT1 transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:14961577 NCBI chr 3:112,019,721...112,068,454
Ensembl chr 3:91,567,001...91,613,643 		JBrowse link
G Xpc XPC complex subunit, DNA damage recognition and repair factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:17325666 PMID:24084170 NCBI chr 4:125,550,833...125,578,084
Ensembl chr 4:123,993,666...124,021,010 		JBrowse link
lung non-small cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A treatment ISO DNA:SNPs: :2677G>T, 3435C>T(human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:20627363 PMID:17534875 RGD:11080964 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 treatment ISO DNA:SNPs: :-24C>T, 3972C>T(human) RGD PMID:17534875 RGD:11080964 NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase treatment ISO human cells in mouse model RGD PMID:26758680 RGD:126925226 NCBI chr 3:35,377,587...35,480,843
Ensembl chr 3:14,979,853...15,083,065 		JBrowse link
G Acvr1b activin A receptor type 1B susceptibility ISO DNA:SNP:intron:rs12809597(human) RGD PMID:22586632 RGD:151665491 NCBI chr 7:134,164,987...134,208,389
Ensembl chr 7:132,286,275...132,329,673 		JBrowse link
G Ada adenosine deaminase ISO protein:decreased expression:lymphocyte,erythrocyte: RGD PMID:31375946 RGD:152995295 NCBI chr 3:172,818,174...172,842,283
Ensembl chr 3:152,398,747...152,447,088 		JBrowse link
G Adam28 ADAM metallopeptidase domain 28 treatment ISO DNA:hypermethylation:promoter RGD PMID:22354764 PMID:21429053 RGD:153297789, RGD:153298914 NCBI chr15:50,184,286...50,250,605
Ensembl chr15:42,944,467...43,840,672 		JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19027488 NCBI chr11:38,418,565...38,427,384
Ensembl chr11:24,931,761...24,941,103 		JBrowse link
G Ager advanced glycosylation end product-specific receptor ISO mRNA, protein:decreased expression:lung (human) RGD PMID:15539404 RGD:7245515 NCBI chr20:4,152,758...4,155,956
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17094902 NCBI chr17:70,720,397...70,747,285
Ensembl chr17:65,810,475...65,837,326 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 ameliorates
treatment		 ISO human cells in mouse model RGD PMID:21277552 PMID:32276600 PMID:23632475 RGD:5133243, RGD:151357000, RGD:150404268 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Akt3 AKT serine/threonine kinase 3 disease_progression ISO RGD PMID:19846969 RGD:13432583 NCBI chr13:91,475,839...91,758,060
Ensembl chr13:88,946,091...89,225,708 		JBrowse link
G Alb albumin disease_progression ISO RGD PMID:23778417 RGD:11036091 NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Alk ALK receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:17625570 PMID:20979469 PMID:20979473 PMID:21102269 PMID:21336183 More... NCBI chr 6:28,631,431...29,351,321
Ensembl chr 6:22,880,625...23,598,034 		JBrowse link
G Amd1 adenosylmethionine decarboxylase 1 disease_progression ISO DNA:SNP: :rs1279590(human) RGD PMID:30650190 RGD:14390072 NCBI chr20:43,695,783...43,711,476
Ensembl chr20:43,697,237...43,711,476 		JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 ISO mRNA:decreased expression:lung RGD PMID:28982084 RGD:13703106 NCBI chr 7:27,381,392...27,466,772
Ensembl chr 7:25,494,609...25,579,540 		JBrowse link
G Apc APC regulator of WNT signaling pathway ISO CTD Direct Evidence: marker/mechanism CTD PMID:18337602 NCBI chr18:26,138,382...26,196,021
Ensembl chr18:25,864,222...25,922,696 		JBrowse link
G Areg amphiregulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:15496427 PMID:16230376 NCBI chr14:17,256,384...17,265,641
Ensembl chr14:16,972,187...16,981,535 		JBrowse link
G Arid1a AT-rich interaction domain 1A disease_progression
treatment		 ISO protein:decreased expression:lung (human)
DNA:mutations 		RGD PMID:24566899 PMID:32791957 RGD:126848781, RGD:126848874 NCBI chr 5:151,192,014...151,269,291
Ensembl chr 5:145,908,181...145,985,564 		JBrowse link
G Arid1b AT-rich interaction domain 1B treatment ISO DNA:mutations RGD PMID:32791957 RGD:126848874 NCBI chr 1:47,973,199...48,328,793
Ensembl chr 1:45,563,623...45,923,493 		JBrowse link
G Arpc5 actin related protein 2/3 complex, subunit 5 ISO mRNA:increased expression:lung (human) RGD PMID:22089643 RGD:11049488 NCBI chr13:64,904,504...64,913,413
Ensembl chr13:64,887,136...64,913,410 		JBrowse link
G Atf3 activating transcription factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17043644 NCBI chr13:105,274,103...105,331,653
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Atm ATM serine/threonine kinase susceptibility
treatment		 ISO DNA:SNPs,haplotypes:intron: (rs227060, rs170548) (human)
human cells in mouse model		 RGD PMID:17582598 PMID:23632475 RGD:150383340, RGD:150404268 NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Aven apoptosis and caspase activation inhibitor ISO CTD Direct Evidence: marker/mechanism CTD PMID:15496427 NCBI chr 3:99,299,009...99,431,635
Ensembl chr 3:99,298,930...99,431,634 		JBrowse link
G Axin1 axin 1 disease_progression ISO protein:decreased expression:lung (human) RGD PMID:19735876 RGD:150530290 NCBI chr10:15,667,894...15,720,092
Ensembl chr10:15,163,684...15,215,615 		JBrowse link
G Axl Axl receptor tyrosine kinase ISO CTD Direct Evidence: therapeutic CTD PMID:22751098 NCBI chr 1:90,392,864...90,424,123
Ensembl chr 1:81,265,088...81,296,265 		JBrowse link
G Bad BCL2-associated agonist of cell death disease_progression ISO protein:decreased expression:lung RGD PMID:21918885 PMID:24092988 RGD:13432584, RGD:13434906 NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bag6 BAG cochaperone 6 susceptibility ISO DNA:SNP: :rs3117582(human) RGD PMID:25884493 RGD:14390136 NCBI chr20:3,680,607...3,693,329
Ensembl chr20:3,675,938...3,688,657 		JBrowse link
G Bambi BMP and activin membrane-bound inhibitor ISO mRNA,protein:increased expression:lung: RGD PMID:20716422 RGD:14390157 NCBI chr17:58,816,438...58,821,003
Ensembl chr17:54,121,255...54,126,060 		JBrowse link
G Bard1 BRCA1 associated RING domain 1 disease_progression ISO RGD PMID:21815143 RGD:127229947 NCBI chr 9:80,069,960...80,144,167
Ensembl chr 9:72,623,155...72,694,265 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator treatment ISO human cells in mouse model RGD PMID:23632475 RGD:150404268 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bbc3 Bcl-2 binding component 3 treatment ISO human cells in mouse model RGD PMID:23632475 RGD:150404268 NCBI chr 1:86,141,450...86,150,666
Ensembl chr 1:77,014,543...77,022,509 		JBrowse link
G Bcl11a BCL11 transcription factor A severity ISO mRNA, protein:increased expression:lung (human) RGD PMID:23758992 RGD:11099968 NCBI chr14:102,230,147...102,325,289
Ensembl chr14:98,030,461...98,124,180 		JBrowse link
G Bcorl1 BCL6 co-repressor-like 1 severity ISO RGD PMID:26648304 RGD:11342082 NCBI chr  X:132,394,703...132,462,414
Ensembl chr  X:127,537,538...127,584,087 		JBrowse link
G Bend4 BEN domain containing 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28722770 NCBI chr14:40,753,048...40,788,686
Ensembl chr14:40,753,077...40,783,504 		JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 exacerbates ISO protein:increased expression:lung (human) RGD PMID:27737687 RGD:152998985 NCBI chr 8:13,253,697...13,273,672
Ensembl chr 8:4,968,842...4,988,732 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 exacerbates
ameliorates		 ISO protein:increased expression:lung (human)
DNA:SNP:intron: (rs11225211) (human)		 RGD PMID:27737687 PMID:32905523 PMID:20959404 RGD:152998985, RGD:153297804, RGD:152999005 NCBI chr 8:13,285,702...13,313,329
Ensembl chr 8:5,000,845...5,015,802 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16382892 NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase ISO ClinVar Annotator: match by term: Non-small cell lung cancer | ClinVar Annotator: match by term: Non-small cell lung carcinoma ClinVar
RGD		 PMID:2102266 PMID:12068308 PMID:12198537 PMID:12447372 PMID:12460918 More... RGD:5133243, RGD:5133242 NCBI chr 4:69,329,772...69,476,931
Ensembl chr 4:68,384,649...68,510,463 		JBrowse link
G Brca1 BRCA1, DNA repair associated disease_progression
treatment		 ISO DNA:hypermethylation:promoter RGD PMID:23128816 PMID:23335114 PMID:24443257 PMID:21575522 RGD:126925968, RGD:127229949, RGD:127229948, RGD:127229935 NCBI chr10:86,917,693...86,978,012
Ensembl chr10:86,418,000...86,477,304 		JBrowse link
G Brd7 bromodomain containing 7 disease_progression ISO protein:increased expression:lung: RGD PMID:22008115 RGD:9586442 NCBI chr19:34,882,238...34,910,944
Ensembl chr19:18,709,022...18,737,494 		JBrowse link
G Btk Bruton tyrosine kinase ameliorates ISO mRNA:increased expression:lung (human) RGD PMID:32623229 RGD:151347854 NCBI chr  X:102,016,070...102,055,448
Ensembl chr  X:97,722,802...97,761,853 		JBrowse link
G Calr calreticulin ameliorates ISO protein:increased expression:lung (human)
mRNA, protein:increased expression:lung (human)		 RGD PMID:26842877 PMID:29228584 RGD:150521685, RGD:150521696 NCBI chr19:40,213,367...40,218,262
Ensembl chr19:23,308,351...23,313,414 		JBrowse link
G Car12 carbonic anhydrase 12 disease_progression ISO RGD PMID:23910904 RGD:155226863 NCBI chr 8:76,169,723...76,225,465
Ensembl chr 8:67,274,359...67,330,440 		JBrowse link
G Car9 carbonic anhydrase 9 disease_progression ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:30381462 PMID:23910904 RGD:155226863 NCBI chr 5:62,559,024...62,565,626
Ensembl chr 5:57,763,206...57,769,838 		JBrowse link
G Casp3 caspase 3 ISO DNA:SNP: :77G>A (human)
mRNA:increased expression:lung		 RGD PMID:20661084 PMID:16231180 RGD:13434908, RGD:13434909 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp6 caspase 6 ISO mRNA:increased expression:lung RGD PMID:16231180 RGD:13434909 NCBI chr 2:221,140,287...221,152,727
Ensembl chr 2:218,466,076...218,478,502 		JBrowse link
G Casp7 caspase 7 ISO DNA:SNP: :rs2227310 (human) RGD PMID:20661084 RGD:13434908 NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:255,437,172...255,476,729 		JBrowse link
G Casp8 caspase 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20471133 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 no_association ISO DNA, mRNA:SNP, decreased expression:exon, lung:rs1052576 (human)
mRNA:increased expression:lung
mRNA:splice variant:lung
DNA:SNP: :rs4645981 (human)
DNA:SNP:exon:rs1052571 (human)		 RGD PMID:17285546 PMID:16231180 PMID:20972334 PMID:20661084 PMID:17285546 RGD:13434907, RGD:13434909, RGD:9999427, RGD:13434908, RGD:13434907 Ensembl chr 5:154,109,046...154,126,626 JBrowse link
G Cat catalase ISO CTD Direct Evidence: marker/mechanism CTD PMID:11731445 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cbl Cbl proto-oncogene ISO DNA:missense mutations, loss of heterozygosity:multiple (human) RGD PMID:20126411 RGD:11576301 NCBI chr 8:53,384,656...53,468,067
Ensembl chr 8:44,489,410...44,571,176 		JBrowse link
G Cblb Cbl proto-oncogene B disease_progression
treatment
no_association		 ISO DNA:SNPs: :rs2305035, rs9657904 (human)
DNA:SNP,haplotype: :rs2305035(human)
DNA:SNPs: :rs3772534 (human)		 RGD PMID:29707316 PMID:26732495 PMID:29707316 RGD:126925239, RGD:150540334, RGD:126925239 NCBI chr11:62,058,829...62,225,904
Ensembl chr11:48,592,703...48,756,839 		JBrowse link
G Ccnb1 cyclin B1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34837450 NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Ccnd1 cyclin D1 disease_progression
treatment		 ISO DNA:amplification
mRNA:splice variant
DNA:SNP: :870A>G (human)		 RGD PMID:26055143 PMID:9462706 PMID:18715616 PMID:16406195 RGD:11052612, RGD:13434928, RGD:13434926, RGD:13434924 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccnd2 cyclin D2 ISO mRNA:increased expression:lung
protein:increased expression:lung		 RGD PMID:31253987 PMID:30227870 RGD:151665100, RGD:151665108 NCBI chr 4:161,653,048...161,675,422
Ensembl chr 4:159,962,363...159,989,495 		JBrowse link
G Ccne1 cyclin E1 disease_progression ISO RGD PMID:11212263 RGD:13673913 NCBI chr 1:99,918,672...99,927,986
Ensembl chr 1:90,781,949...90,791,101 		JBrowse link
G Ccnh cyclin H ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr 2:17,570,449...17,591,078
Ensembl chr 2:15,834,833...15,855,819 		JBrowse link
G Cd74 CD74 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:22919003 NCBI chr18:56,527,071...56,536,406
Ensembl chr18:54,256,778...54,266,003 		JBrowse link
G Cd9 CD9 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:17043644 NCBI chr 4:159,942,553...159,975,463
Ensembl chr 4:158,256,328...158,289,222 		JBrowse link
G Cda cytidine deaminase ISO DNA:snp:cds:p.K27Q (human) RGD PMID:18347182 RGD:2316365 NCBI chr 5:150,556,615...150,583,231
Ensembl chr 5:150,556,615...150,583,231 		JBrowse link
G Cdh13 cadherin 13 ISO DNA:hypermethylation:promoter
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:18337602 PMID:11389090 RGD:2293545 NCBI chr19:63,258,251...64,296,122
Ensembl chr19:46,349,430...47,387,459 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 disease_progression
treatment		 ISO RGD PMID:24959380 PMID:24496383 RGD:13464275, RGD:13464276 NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:62,883,105...62,942,403 		JBrowse link
G Cdk6 cyclin-dependent kinase 6 treatment ISO RGD PMID:27874949 PMID:23591808 RGD:13464321, RGD:13464324 NCBI chr 4:31,592,384...31,784,732
Ensembl chr 4:30,646,460...30,829,634 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A treatment ISO human cells in mouse model RGD PMID:23632475 RGD:150404268 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B disease_progression ISO RGD PMID:9500468 RGD:13673920 NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:18337602 PMID:19375815 NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B disease_progression ISO DNA:hypermethylation:promoter RGD PMID:11445839 RGD:13673922 NCBI chr 5:109,123,308...109,134,906
Ensembl chr 5:104,010,680...104,019,050 		JBrowse link
G Cenpa centromere protein A severity ISO mRNA:increased expression:lung (human) RGD PMID:30008938 RGD:36947379 NCBI chr 6:31,420,062...31,431,703
Ensembl chr 6:25,700,142...25,711,675 		JBrowse link
G Cert1 ceramide transporter 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15496427 NCBI chr 2:29,617,202...29,721,734
Ensembl chr 2:27,882,555...27,987,074 		JBrowse link
G Chfr checkpoint with forkhead and ring finger domains ISO CTD Direct Evidence: marker/mechanism CTD PMID:20705357 NCBI chr12:52,164,214...52,197,860
Ensembl chr12:46,504,497...46,538,014 		JBrowse link
G Chga chromogranin A ISO CTD Direct Evidence: marker/mechanism CTD PMID:21595568 NCBI chr 6:127,460,895...127,472,238
Ensembl chr 6:121,696,051...121,707,398 		JBrowse link
G Chi3l1 chitinase 3 like 1 severity ISO protein:increased secretion:serum (human) RGD PMID:20564116 RGD:4892660 NCBI chr13:48,193,839...48,201,822
Ensembl chr13:45,641,802...45,649,787 		JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit disease_progression
susceptibility		 ISO DNA:SNP: :rs6495309(human)
DNA:SNP:exon: (rs1051730) (human) 		RGD PMID:22722785 PMID:21747048 RGD:151347532, RGD:151660346 NCBI chr 8:64,297,755...64,311,251
Ensembl chr 8:55,401,702...55,415,165 		JBrowse link
G Chrna5 cholinergic receptor nicotinic alpha 5 subunit disease_progression ISO DNA:SNP: :rs667282(human) RGD PMID:27050379 RGD:150527847 NCBI chr 8:64,265,879...64,294,233
Ensembl chr 8:55,369,794...55,398,146 		JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit ameliorates ISO RGD PMID:19151195 PMID:19326440 RGD:151667906, RGD:151667908 NCBI chr 1:126,123,425...126,249,181
Ensembl chr 1:116,714,711...116,837,240 		JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit severity ISO RGD PMID:25172267 RGD:151361147 NCBI chr 8:64,312,644...64,333,319
Ensembl chr 8:55,418,313...55,437,027 		JBrowse link
G Clptm1l CLPTM1-like disease_progression
no_association		 ISO CTD Direct Evidence: marker/mechanism
DNA:SNPs: :rs4975616,rs401681(human)
DNA:SNP: :rs31490(human)
DNA:SNPs:: rs401681,rs4975616(human)		 CTD
RGD		 PMID:22675468 PMID:24679952 PMID:27982019 PMID:24175795 RGD:150530644, RGD:150530632, RGD:150530500 NCBI chr 1:31,496,094...31,512,148
Ensembl chr 1:29,667,545...29,683,530 		JBrowse link
G Cmpk1 cytidine/uridine monophosphate kinase 1 severity ISO DNA:snps:intron:IVS1+1057C>A rs4492666, IVS1-928C>A rs11211524 (human) RGD PMID:21642870 RGD:5133252 NCBI chr 5:128,480,301...128,507,830
Ensembl chr 5:128,480,301...128,507,830 		JBrowse link
G Col7a1 collagen type VII alpha 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:30381462 NCBI chr 8:118,483,364...118,515,736
Ensembl chr 8:109,604,861...109,637,252 		JBrowse link
G Coro1c coronin 1C ISO CTD Direct Evidence: marker/mechanism CTD PMID:15496427 NCBI chr12:48,373,573...48,445,718
Ensembl chr12:42,712,991...42,785,179 		JBrowse link
G Csf1r colony stimulating factor 1 receptor ameliorates
severity		 ISO human cells in a mouse model
mRNA,protein:increased expression:lung (human)
mRNA:decreased expression:lung (human)
DNA:missense mutation:CDS:p.H362R (rs10079250) (human)		 RGD PMID:27486763 PMID:33428598 PMID:24451080 PMID:28449811 RGD:150524288, RGD:150524295, RGD:150524294, RGD:150524292 NCBI chr18:56,834,152...56,860,804
Ensembl chr18:54,546,659...54,590,415 		JBrowse link
G Csf3 colony stimulating factor 3 ISO CTD Direct Evidence: therapeutic CTD PMID:7692001 NCBI chr10:84,157,485...84,159,860
Ensembl chr10:83,661,207...83,663,603 		JBrowse link
G Cst6 cystatin E/M ISO CTD Direct Evidence: marker/mechanism CTD PMID:17043644 NCBI chr 1:212,084,676...212,086,384
Ensembl chr 1:202,655,322...202,657,030 		JBrowse link
G Ctdspl CTD small phosphatase like ISO mRNA:decreased expression:lung (human) RGD PMID:22491060 RGD:153350086 NCBI chr 8:127,520,478...127,644,999
Ensembl chr 8:118,642,672...118,767,117 		JBrowse link
G Cux1 cut-like homeobox 1 exacerbates ISO mRNA:increased expression:lung (human) RGD PMID:28405678 RGD:152985544 NCBI chr12:25,728,393...26,062,497
Ensembl chr12:20,107,311...20,425,866
Ensembl chr 4:20,107,311...20,425,866 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 disease_progression ISO protein:increased expression:lung (human) RGD PMID:22977534 RGD:152023747 NCBI chr13:42,630,383...42,634,288
Ensembl chr13:40,077,976...40,081,883 		JBrowse link
G Cycs cytochrome c, somatic severity
treatment		 ISO protein:decreased expression:serum RGD PMID:25578497 PMID:25578497 RGD:13792769, RGD:13792769 NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054 		JBrowse link
G Cyld CYLD lysine 63 deubiquitinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:17043644 NCBI chr19:34,487,491...34,547,311
Ensembl chr19:18,314,019...18,373,658 		JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 exacerbates
susceptibility
disease_progression		 ISO mRNA:increased expression:lung (human)
DNA:SNPs:multiple (human)
DNA:SNPs:CDS, 3' utr: (rs6068816, rs4809957) (human)
DNA:SNP:exon, intron: (rs6068816, rs2181874) (human)
DNA:SNP:intron 4: (rs3787554) (human)		 RGD PMID:29250167 PMID:29726119 PMID:17671213 PMID:25544771 PMID:27669215 More... RGD:151361179, RGD:151708739, RGD:151708738, RGD:151665789, RGD:151665175, RGD:151361185, RGD:151361182 NCBI chr 3:179,694,647...179,709,083
Ensembl chr 3:159,275,947...159,290,383 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16142352 NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Dab2ip DAB2 interacting protein disease_progression ISO protein:decreased expression:lung (human) RGD PMID:31849482 RGD:151665206 NCBI chr 3:39,312,745...39,483,730
Ensembl chr 3:18,915,290...19,086,280 		JBrowse link
G Dapk1 death associated protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11313923 NCBI chr17:3,935,826...4,096,858
Ensembl chr17:3,930,213...4,090,991 		JBrowse link
G Ddr1 discoidin domain receptor tyrosine kinase 1 disease_progression ISO RGD PMID:17299390 RGD:150429714 NCBI chr20:3,047,269...3,069,277
Ensembl chr20:3,044,320...3,064,468 		JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 ISO mRNA:decreased expression:lung RGD PMID:17299390 RGD:150429714 NCBI chr13:84,726,412...84,851,032
Ensembl chr13:82,195,463...82,317,363 		JBrowse link
G Deup1 deuterosome assembly protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr 8:12,380,300...12,442,649
Ensembl chr 8:12,380,302...12,442,199 		JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein ISO mRNA:increased expression:lung RGD PMID:16231180 RGD:13434909 NCBI chr12:38,716,668...38,731,285
Ensembl chr12:33,055,263...33,070,387 		JBrowse link
G Dnai7 dynein axonemal intermediate chain 7 ameliorates ISO RGD PMID:24860162 RGD:152998908 NCBI chr 4:178,143,499...178,179,871
Ensembl chr 4:178,143,500...178,179,980 		JBrowse link
G Dnmt1 DNA methyltransferase 1 treatment ISO RGD PMID:32211850 PMID:32211850 RGD:126848780, RGD:126848780 NCBI chr 8:27,716,797...27,763,405
Ensembl chr 8:19,440,611...19,486,659 		JBrowse link
G Dusp3 dual specificity phosphatase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15496427 NCBI chr10:87,420,213...87,434,202
Ensembl chr10:86,920,014...86,933,962 		JBrowse link
G E2f1 E2F transcription factor 1 treatment
disease_progression
severity		 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:29754146 PMID:28498400 PMID:12358350 PMID:12237873 PMID:23543735 RGD:13464333, RGD:13464343, RGD:13464342, RGD:9590260 NCBI chr 3:163,524,739...163,535,563
Ensembl chr 3:143,049,478...143,075,361 		JBrowse link
G E2f2 E2F transcription factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29754146 NCBI chr 5:153,682,789...153,706,087
Ensembl chr 5:148,399,642...148,421,217 		JBrowse link
G E2f3 E2F transcription factor 3 disease_progression ISO DNA:SNP: :rs3806116 (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:29754146 PMID:27557513 RGD:13464345 NCBI chr17:34,810,355...34,887,725
Ensembl chr17:34,601,830...34,676,253 		JBrowse link
G E2f5 E2F transcription factor 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29754146 NCBI chr 2:86,997,331...87,012,908
Ensembl chr 2:86,997,332...87,012,990 		JBrowse link
G E2f6 E2F transcription factor 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29754146 NCBI chr 6:39,592,224...39,608,685
Ensembl chr 6:39,592,228...39,608,683 		JBrowse link
G E2f7 E2F transcription factor 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29754146 NCBI chr 7:46,150,533...46,192,739
Ensembl chr 7:46,151,293...46,192,734 		JBrowse link
G E2f8 E2F transcription factor 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29754146 NCBI chr 1:107,701,985...107,720,538
Ensembl chr 1:98,565,717...98,584,098 		JBrowse link
G Eef2 eukaryotic translation elongation factor 2 disease_progression ISO protein:increased expression:blood serum (human) RGD PMID:24377563 RGD:153298905 NCBI chr 7:9,183,836...9,196,255
Ensembl chr 7:8,533,116...8,559,183 		JBrowse link
G Egf epidermal growth factor treatment ISO RGD PMID:26927662 PMID:25992884 RGD:13464348, RGD:13464350 NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:218,219,415...218,302,064 		JBrowse link
G Egfr epidermal growth factor receptor ameliorates
severity
treatment
susceptibility		 ISO ClinVar Annotator: match by term: Non-small cell lung cancer | ClinVar Annotator: match by term: Non-small cell lung carcinoma | ClinVar Annotator: match by term: Nonsmall cell lung cancer, response to tyrosine kinase inhibitor in, somatic
human cells in mouse model
CTD Direct Evidence: marker/mechanism
protein:decreased expression:tumor (human)
DNA:deletion:cds:2240del18 (human)		 ClinVar
CTD
RGD		 PMID:11423618 PMID:15118073 PMID:15118125 PMID:15272417 PMID:15329413 More... RGD:5133242, RGD:153344584, RGD:151357000, RGD:126790479, RGD:13464349, RGD:5131629, RGD:5131640, RGD:1601010, RGD:5133241 NCBI chr14:95,378,626...95,551,358
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Egr1 early growth response 1 resistance ISO mRNA:increased expression:tumor (human) RGD PMID:15774784 RGD:5131925 NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 treatment ISO human cells in mouse model RGD PMID:23632475 RGD:150404268 NCBI chr16:71,495,457...71,508,845
Ensembl chr16:64,790,226...64,805,984 		JBrowse link
G Eml4 EMAP like 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17625570 PMID:21757253 PMID:21767331 PMID:22568572 PMID:22617245 More... NCBI chr 6:16,972,054...17,087,365
Ensembl chr 6:11,219,566...11,334,879 		JBrowse link
G Eno1 enolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17094902 NCBI chr 5:166,002,867...166,014,252
Ensembl chr 5:160,719,951...160,731,336
Ensembl chr 3:160,719,951...160,731,336 		JBrowse link
G Eno2 enolase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21595568 NCBI chr 4:159,258,371...159,267,220
Ensembl chr 4:157,572,088...157,580,980 		JBrowse link
G Epas1 endothelial PAS domain protein 1 treatment ISO RGD PMID:21812995 RGD:10395382 NCBI chr 6:13,543,252...13,626,147
Ensembl chr 6:7,790,647...7,871,228 		JBrowse link
G Ephx1 epoxide hydrolase 1 disease_progression ISO RGD PMID:17273734 RGD:4889124 NCBI chr13:95,246,079...95,275,852
Ensembl chr13:92,714,315...92,790,235 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 ISO ClinVar Annotator: match by term: Non-small cell lung carcinoma ClinVar
RGD		 PMID:15457249 PMID:15753357 PMID:16638863 PMID:16863509 PMID:18334834 More... RGD:5133243 NCBI chr10:83,907,491...83,931,365
Ensembl chr10:83,411,313...83,435,078 		JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 treatment
disease_progression		 ISO RGD PMID:20364069 PMID:11789762 RGD:126790478, RGD:126790479 NCBI chr 7:1,579,079...1,600,379
Ensembl chr 7:996,225...1,015,525 		JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit treatment
disease_progression
severity		 ISO CTD Direct Evidence: marker/mechanism
DNA:SNPs:multiple (human)
DNA:silent mutation:cds:p.N118N (human)
protein:decreased expression:lung (human)		 CTD
RGD		 PMID:21553054 PMID:23912706 PMID:28924235 PMID:23549037 PMID:24443257 More... RGD:153323316, RGD:127229950, RGD:127229948, RGD:13207428, RGD:13207308 NCBI chr 1:88,099,308...88,135,966
Ensembl chr 1:78,996,390...79,007,963 		JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit disease_progression
treatment		 ISO DNA:polymorphism:cds:p.K751Q(human)
DNA:SNPs:multiple (human)		 RGD PMID:25596702 PMID:28924235 RGD:12880391, RGD:153323316 NCBI chr 1:88,161,342...88,175,102
Ensembl chr 1:79,033,326...79,047,102 		JBrowse link
G Ercc3 ERCC excision repair 3, TFIIH core complex helicase subunit treatment ISO DNA:snp:intron:c.2064+741T>C (rs3738948) (human) RGD PMID:25069034 RGD:11098167 NCBI chr18:24,157,831...24,188,543
Ensembl chr18:23,883,580...23,914,329 		JBrowse link
G Ercc5 ERCC excision repair 5, endonuclease treatment ISO DNA:SNPs:multiple (human) RGD PMID:24782167 PMID:28924235 RGD:151347410, RGD:153323316 NCBI chr 9:53,801,471...53,846,611
Ensembl chr 9:46,309,389...46,354,472 		JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor treatment ISO DNA:SNP:intron: (rs4253002) (human) RGD PMID:28924235 RGD:153323316 NCBI chr16:7,771,311...7,841,895
Ensembl chr16:7,765,013...7,835,587 		JBrowse link
G Ergic3 ERGIC and golgi 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27588471 NCBI chr 3:164,985,108...164,994,897
Ensembl chr 3:144,525,092...144,534,813 		JBrowse link
G Esr1 estrogen receptor 1 ISO DNA:hypermethylation: :lung RGD PMID:19506903 RGD:4892255 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit disease_progression ISO RGD PMID:21539681 PMID:23300840 RGD:126781700, RGD:126781715 NCBI chr 4:77,624,223...77,698,598
Ensembl chr 4:76,624,399...76,687,362 		JBrowse link
G Fap fibroblast activation protein, alpha disease_progression ISO RGD PMID:29415055 RGD:152600902 NCBI chr 3:67,547,398...67,616,271
Ensembl chr 3:47,138,813...47,225,545 		JBrowse link
G Faslg Fas ligand ISO CTD Direct Evidence: marker/mechanism CTD PMID:21807637 NCBI chr13:76,680,885...76,706,042
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Fat1 FAT atypical cadherin 1 treatment ISO CTD Direct Evidence: therapeutic CTD
RGD		 PMID:34390292 PMID:31085721 RGD:151347689 NCBI chr16:53,909,759...54,029,175
Ensembl chr16:47,177,248...47,296,107 		JBrowse link
G Fbxo11 F-box protein 11 treatment ISO RGD PMID:31778188 RGD:152025265 NCBI chr 6:12,240,348...12,316,223
Ensembl chr 6:6,486,015...6,562,662 		JBrowse link
G Fgf9 fibroblast growth factor 9 severity ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:lung (human)		 CTD
RGD		 PMID:19358281 PMID:24239165 PMID:31884893 RGD:152177524, RGD:152177912 NCBI chr15:36,325,552...36,369,995
Ensembl chr15:32,210,074...32,253,309 		JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 disease_progression ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:22286583 PMID:27794399 PMID:23806793 RGD:25330355 NCBI chr16:73,194,631...73,249,855
Ensembl chr16:66,494,042...66,547,350 		JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 disease_progression
severity		 ISO mRNA, protein:increased expression:lung (human)
DNA:SNP:exon 9: p.G3888R (rs351855) (human)		 RGD PMID:26045670 PMID:23524567 RGD:150429970, RGD:150429982 NCBI chr17:9,466,686...9,481,423
Ensembl chr17:9,461,547...9,476,242 		JBrowse link
G Fh fumarate hydratase severity ISO DNA:SNP: (rs1414493) (human) RGD PMID:25576295 RGD:150340558 NCBI chr13:90,056,565...90,082,450
Ensembl chr13:87,524,337...87,550,266 		JBrowse link
G Fhit fragile histidine triad diadenosine triphosphatase disease_progression ISO CTD Direct Evidence: marker/mechanism
DNA:loss of heterozygosity:intron:		 CTD
RGD		 PMID:11788890 PMID:9635574 PMID:9850082 RGD:13792815, RGD:13792770 NCBI chr15:16,365,401...17,872,901
Ensembl chr15:13,934,995...15,442,340 		JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit disease_progression ISO protein:increased expression:lung (human) RGD PMID:25375657 RGD:11074609 NCBI chr 6:30,017,952...30,039,269
Ensembl chr 6:24,300,956...24,320,034 		JBrowse link
G Foxa1 forkhead box A1 disease_progression ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:lung		 CTD
RGD		 PMID:32717239 PMID:26658322 PMID:26909612 RGD:11554787, RGD:151665747 NCBI chr 6:80,838,380...80,871,195
Ensembl chr 6:75,103,503...75,136,188 		JBrowse link
G Foxa2 forkhead box A2 ISO mRNA:decreased expression:lung RGD PMID:26658322 RGD:11554787 NCBI chr 3:155,923,305...155,927,508
Ensembl chr 3:135,470,131...135,474,326 		JBrowse link
G Foxl2 forkhead box L2 ISO DNA:hypermethylation: (human) RGD PMID:23599765 RGD:13503323 NCBI chr 8:108,392,466...108,395,553
Ensembl chr 8:99,513,303...99,514,427 		JBrowse link
G Foxm1 forkhead box M1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18345025 PMID:19672312 NCBI chr 4:163,325,628...163,338,100
Ensembl chr 4:161,638,816...161,650,684 		JBrowse link
G Foxo3 forkhead box O3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19380174 NCBI chr20:47,251,968...47,348,254
Ensembl chr20:45,672,995...45,764,561 		JBrowse link
G Foxp1 forkhead box P1 ISO mRNA:decreased expression:lung (human) RGD PMID:22491060 RGD:153350086 NCBI chr 4:133,117,346...133,808,647
Ensembl chr 4:131,564,756...132,112,258 		JBrowse link
G Frzb frizzled-related protein ISO DNA:hypermethylation:exon 1 RGD PMID:27623992 RGD:32716395 NCBI chr 3:85,739,162...85,772,168
Ensembl chr 3:65,332,277...65,365,208 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:15496427 NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gipr gastric inhibitory polypeptide receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:17094902 NCBI chr 1:78,804,287...78,814,462
Ensembl chr 1:78,805,593...78,814,462 		JBrowse link
G Gnaq G protein subunit alpha q disease_progression ISO RGD PMID:24518087 RGD:126781753 NCBI chr 1:222,852,453...223,098,754
Ensembl chr 1:213,424,465...213,667,672 		JBrowse link
G Gpr135 G protein-coupled receptor 135 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28722770 NCBI chr 6:90,627,533...90,630,661
Ensembl chr 6:90,629,178...90,630,551 		JBrowse link
G Gpx1 glutathione peroxidase 1 treatment
onset		 ISO DNA:SNP: (human)
mRNA:increased expression:leukocyte (human)		 RGD PMID:19347979 PMID:33474835 RGD:152998881, RGD:152998904 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Grik2 glutamate ionotropic receptor kainate type subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr20:53,717,564...54,415,283
Ensembl chr20:52,133,851...52,838,375 		JBrowse link
G Grp gastrin releasing peptide disease_progression ISO protein:increased expression:serum (human) RGD PMID:30146822 RGD:401700396 NCBI chr18:61,658,655...61,672,037
Ensembl chr18:59,388,274...59,402,061 		JBrowse link
G Gstm2 glutathione S-transferase mu 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19900515 NCBI chr 2:198,312,179...198,316,962
Ensembl chr 2:195,544,426...195,628,961 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 susceptibility ISO DNA:SNP: :p.A114V (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphism:exon:p.I105V (human)		 CTD
RGD		 PMID:17094902 PMID:18258609 PMID:19174490 RGD:4140950, RGD:4140944 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G H19 H19 imprinted maternally expressed transcript disease_progression ISO mRNA:increased expression:lung (human) RGD PMID:30280776 RGD:126925764 NCBI chr 1:207,160,175...207,162,851
Ensembl chr 1:197,730,698...197,733,134 		JBrowse link
G Hdac3 histone deacetylase 3 ISO RGD PMID:24482232 RGD:9588265 NCBI chr18:30,021,847...30,041,061
Ensembl chr18:29,770,636...29,793,856 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21994468 NCBI chr11:84,210,632...84,213,045
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:30381462 PMID:21812995 RGD:10395382 NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 ISO protein:increased expression:lung (human) RGD PMID:20716340 RGD:9999189 NCBI chr 7:136,253,633...136,260,085
Ensembl chr 7:134,375,150...134,381,609 		JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 susceptibility ISO antibody 703D4 recognizes Hnrnpa2b1 protein (RGD:9685415);protein:increased expression:sputum (human) RGD PMID:2846790 RGD:9685413 NCBI chr 4:81,867,354...81,875,886
Ensembl chr 4:80,534,651...80,545,249 		JBrowse link
G Hras HRas proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Non-small cell lung carcinoma ClinVar PMID:2674130 PMID:3004741 PMID:3283542 PMID:3304147 PMID:6287572 More... NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:196,296,263...196,300,615 		JBrowse link
G Hs3st2 heparan sulfate-glucosamine 3-sulfotransferase 2 ISO DNA:hypermethylation RGD PMID:27777637 RGD:152998954 NCBI chr 1:185,387,445...185,508,700
Ensembl chr 1:175,956,157...176,077,399 		JBrowse link
G Htra1 HtrA serine peptidase 1 exacerbates ISO protein:decreased expression:lung (human) RGD PMID:32878625 RGD:152975629 NCBI chr 1:194,928,069...194,977,619
Ensembl chr 1:185,497,735...185,547,379 		JBrowse link
G Icam1 intercellular adhesion molecule 1 disease_progression ISO progression-free survival; protein:increased secretion:serum (human) RGD PMID:19949019 RGD:4145465 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 severity ISO DNA:SNP: (rs11540478) (human) RGD PMID:25576295 RGD:150340558 NCBI chr 1:143,447,925...143,467,248
Ensembl chr 1:134,029,772...134,058,025 		JBrowse link
G Ikzf2 IKAROS family zinc finger 2 exacerbates ISO protein:decreased expression:venous blood, lung, regulatory T cell (human) RGD PMID:26460798 RGD:151347635 NCBI chr 9:78,495,670...78,640,896
Ensembl chr 9:71,042,440...71,190,867 		JBrowse link
G Ikzf3 IKAROS family zinc finger 3 exacerbates ISO protein:increased expression:lung (human) RGD PMID:24823637 RGD:151347636 NCBI chr10:83,956,850...84,049,861
Ensembl chr10:83,465,745...83,553,591 		JBrowse link
G Il10 interleukin 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20471133 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il18 interleukin 18 ISO protein:increased expression:serum RGD PMID:15955140 RGD:4889836 NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il1a interleukin 1 alpha ISO DNA:SNPs: : RGD PMID:19505916 RGD:4142793 NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta susceptibility ISO DNA:polymorphism: :-31T>C (human) RGD PMID:16126303 RGD:4143167 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1rn interleukin 1 receptor antagonist susceptibility ISO DNA:polymorphism (human) RGD PMID:16126303 RGD:4143167 NCBI chr 3:27,509,836...27,525,738
Ensembl chr 3:7,111,550...7,127,445 		JBrowse link
G Il6r interleukin 6 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:22552503 NCBI chr 2:177,582,020...177,646,705
Ensembl chr 2:175,298,686...175,347,536 		JBrowse link
G Il7 interleukin 7 disease_progression ISO RGD PMID:21159243 RGD:151347686 NCBI chr 2:96,142,523...96,186,282
Ensembl chr 2:94,234,766...94,280,075 		JBrowse link
G Il7r interleukin 7 receptor disease_progression
susceptibility		 ISO DNA:SNPs:: rs1494555,rs7737000(human) RGD PMID:21159243 PMID:19505916 RGD:151347686, RGD:4142793 NCBI chr 2:60,179,561...60,204,937
Ensembl chr 2:58,454,217...58,477,757 		JBrowse link
G Iqsec1 IQ motif and Sec7 domain ArfGEF 1 ISO mRNA:decreased expression:lung (human) RGD PMID:22491060 RGD:153350086 NCBI chr 4:124,725,917...125,045,351
Ensembl chr 4:123,168,719...123,488,172 		JBrowse link
G Irf1 interferon regulatory factor 1 ISO ClinVar Annotator: match by term: Non-small cell lung carcinoma ClinVar
RGD		 PMID:10395927 PMID:10395927 RGD:1600014 NCBI chr10:38,417,935...38,424,946
Ensembl chr10:37,916,670...37,924,166 		JBrowse link
G Irs4 insulin receptor substrate 4 ISO protein:increased expression:lung (human) RGD PMID:33894221 RGD:151347872 NCBI chr  X:110,132,490...110,148,473 JBrowse link
G Itga9 integrin subunit alpha 9 ISO mRNA:decreased expression:lung (human) RGD PMID:22491060 RGD:153350086 NCBI chr 8:127,185,244...127,493,296
Ensembl chr 8:118,307,381...118,613,754 		JBrowse link
G Itgb1 integrin subunit beta 1 ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:lung		 CTD
RGD		 PMID:21478906 PMID:28537888 RGD:13792830 NCBI chr19:73,602,277...73,650,271
Ensembl chr19:56,705,171...56,753,195 		JBrowse link
G Itgb3 integrin subunit beta 3 ISO RGD PMID:19386436 RGD:5037228 NCBI chr10:90,009,927...90,067,787
Ensembl chr10:89,509,989...89,564,679 		JBrowse link
G Itgb4 integrin subunit beta 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27107458 NCBI chr10:101,705,592...101,741,933
Ensembl chr10:101,206,665...101,243,012 		JBrowse link
G Jak1 Janus kinase 1 disease_progression ISO protein:increased phosphorylation:lung RGD PMID:28989534 RGD:150524360 NCBI chr 5:120,895,606...121,004,207
Ensembl chr 5:115,780,248...115,888,926 		JBrowse link
G Jak2 Janus kinase 2 treatment ISO human cells in mouse model RGD PMID:25869210 PMID:21325979 RGD:149735332, RGD:149735342 NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit severity ISO RNA:increased expression:lung (human) RGD PMID:29895215 RGD:151347665 NCBI chr19:40,081,126...40,082,910
Ensembl chr19:23,176,294...23,178,035 		JBrowse link
G Kat2a lysine acetyltransferase 2A disease_progression ISO RGD PMID:23543735 RGD:9590260 NCBI chr10:86,132,535...86,140,877
Ensembl chr10:85,632,216...85,640,166 		JBrowse link
G Kdm1a lysine demethylase 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:22493729 NCBI chr 5:154,066,436...154,121,913
Ensembl chr 5:148,782,976...148,838,319 		JBrowse link
G Kdm2a lysine demethylase 2A severity ISO mRNA:increased expression:stomach (human)
human gene in a mouse model		 RGD PMID:24200691 PMID:24482232 RGD:9588263, RGD:9588265 NCBI chr 1:211,041,859...211,125,749
Ensembl chr 1:201,612,453...201,680,787 		JBrowse link
G Kdm3b lysine demethylase 3B ISO DNA:amplification:lung, peripheral blood mononuclear cell (human) RGD PMID:18975135 RGD:9586737 NCBI chr18:26,655,004...26,710,814
Ensembl chr18:26,380,964...26,436,628 		JBrowse link
G Kdm5a lysine demethylase 5A severity ISO protein:increased expression:lung (human) RGD PMID:25162518 RGD:9588530 NCBI chr 4:155,238,124...155,316,121
Ensembl chr 4:153,565,846...153,642,422 		JBrowse link
G Kdm6a lysine demethylase 6A exacerbates ISO human cells in a mouse model RGD PMID:32879445 RGD:150429731 NCBI chr  X:6,920,374...7,060,027
Ensembl chr  X:4,337,750...4,477,062 		JBrowse link
G Kdr kinase insert domain receptor disease_progression
treatment		 ISO DNA:CNVs
protein:increased expression:plasma
DNA:SNP:promoter:���906T>C (rs2071559) (human)
DNA, protein:CNVs, increased expression:lung		 RGD PMID:21724587 PMID:21481963 PMID:25975224 PMID:12415261 PMID:16697074 More... RGD:126908001, RGD:126925199, RGD:126925198, RGD:126925192, RGD:126925189, RGD:126925188 NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,217,871...32,261,018 		JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22684020 NCBI chr 8:28,044,555...28,054,042
Ensembl chr 8:19,768,375...19,777,862 		JBrowse link
G Kif5b kinesin family member 5B ISO CTD Direct Evidence: marker/mechanism CTD PMID:21757253 NCBI chr17:56,185,386...56,222,990
Ensembl chr17:51,489,944...51,527,508 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:24688052 NCBI chr14:32,901,615...32,978,895
Ensembl chr14:32,548,877...32,624,652 		JBrowse link
G Kmt2c lysine methyltransferase 2C disease_progression ISO RGD PMID:33665490 RGD:150523771 NCBI chr 4:10,353,698...10,755,965
Ensembl chr 4:9,609,627...9,833,539 		JBrowse link
G Kmt2d lysine methyltransferase 2D disease_progression ISO DNA, protein:missense mutations, nonsense mutations, frameshift mutation, increased expression:lung RGD PMID:29627316 PMID:33665490 PMID:25112956 RGD:150523767, RGD:150523771, RGD:150523769 NCBI chr 7:131,859,696...131,901,032
Ensembl chr 7:129,962,887...130,020,325 		JBrowse link
G Kras KRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Non-small cell lung cancer | ClinVar Annotator: match by term: Non-small cell lung carcinoma
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
RGD		 PMID:1875403 PMID:2547513 PMID:3627975 PMID:6320174 PMID:6695174 More... RGD:5133242 NCBI chr 4:179,916,255...179,949,613 JBrowse link
G L1cam L1 cell adhesion molecule disease_progression ISO RGD PMID:22307136 RGD:11570503 NCBI chr  X:156,748,597...156,775,116
Ensembl chr  X:151,597,277...151,623,857 		JBrowse link
G Lamb3 laminin subunit beta 3 ISO mRNA:increased expression:lung: RGD PMID:10964684 RGD:13793368 NCBI chr13:107,362,514...107,404,081
Ensembl chr13:104,833,873...104,875,405 		JBrowse link
G Lamc2 laminin subunit gamma 2 disease_progression ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:lung:		 CTD
RGD		 PMID:30381462 PMID:26180921 PMID:10964684 RGD:13793367, RGD:13793368 NCBI chr13:67,835,199...67,894,694
Ensembl chr13:65,284,664...65,344,200 		JBrowse link
G Lep leptin ISO protein:increased expression:serum RGD PMID:19033693 RGD:5128815 NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Lgals1 galectin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17094902 NCBI chr 7:112,365,695...112,368,801
Ensembl chr 7:110,481,392...110,488,345 		JBrowse link
G Lrp1b LDL receptor related protein 1B ameliorates ISO DNA:mutations:multiple: (human) RGD PMID:31164891 RGD:150429775 NCBI chr 3:45,004,001...47,125,147
Ensembl chr 3:24,594,991...26,715,505 		JBrowse link
G Lrrc56 leucine rich repeat containing 56 ISO ClinVar Annotator: match by term: Non-small cell lung carcinoma ClinVar PMID:2674130 PMID:3004741 PMID:3283542 PMID:3304147 PMID:6287572 More... NCBI chr 1:205,729,402...205,744,754
Ensembl chr 1:196,299,846...196,315,172 		JBrowse link
G Lrrc59 leucine rich repeat containing 59 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr10:80,069,162...80,083,820
Ensembl chr10:79,572,317...79,602,533 		JBrowse link
G Lta lymphotoxin alpha ISO protein:increased expression:lung RGD PMID:9669810 RGD:4143264 NCBI chr20:3,622,291...3,625,852
Ensembl chr20:3,618,853...3,620,859 		JBrowse link
G Ltf lactotransferrin ISO RGD PMID:21532506 RGD:7243860 NCBI chr 8:119,878,344...119,901,189
Ensembl chr 8:110,999,948...111,022,795 		JBrowse link
G Macir macrophage immunometabolism regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr 9:105,868,072...105,888,128
Ensembl chr 9:98,420,376...98,441,733 		JBrowse link
G Manf mesencephalic astrocyte-derived neurotrophic factor susceptibility ISO RGD PMID:8971156 RGD:1599219 NCBI chr 8:116,427,053...116,430,259
Ensembl chr 8:107,548,352...107,551,438 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 ameliorates ISO ClinVar Annotator: match by term: Non-small cell lung carcinoma
ClinVar Annotator: match by term: Non-small cell lung cancer | ClinVar Annotator: match by term: Non-small cell lung carcinoma		 ClinVar
RGD		 PMID:7651428 PMID:17704260 PMID:18060073 PMID:18632602 PMID:19411838 More... RGD:5133242, RGD:150530476, RGD:5133243 NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:64,683,449...64,755,147 		JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 ameliorates ISO RGD PMID:21514245 RGD:150530476 NCBI chr 7:9,241,449...9,264,216
Ensembl chr 7:8,580,905...8,610,243 		JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 ameliorates ISO associated with Postoperative Complications;DNA:SNP:intron: (rs12452497)(human) RGD PMID:26165383 RGD:11521299 NCBI chr10:50,842,348...50,947,063
Ensembl chr10:50,344,915...50,447,993 		JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 susceptibility
exacerbates		 ISO DNA:SNP:3' utr: (rs3679) (human) RGD PMID:27861856 PMID:21317887 RGD:155230827, RGD:155249848 NCBI chr12:7,389,032...7,398,377
Ensembl chr12:2,591,219...2,604,222 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 severity ISO DNA:SNPs:5'-UTR, intron 1: (rs17661089, rs16886403, rs726501) (human) RGD PMID:21636554 RGD:150573805 NCBI chr 2:45,081,889...45,150,555
Ensembl chr 2:43,350,098...43,414,463 		JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 disease_progression ISO RGD PMID:28393206 PMID:23533274 RGD:151356965, RGD:151356978 NCBI chr17:58,078,175...58,098,455
Ensembl chr17:53,383,131...53,403,216 		JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member disease_progression
ameliorates
severity		 ISO protein:increased expression:lung, cytoplasm (human)
human cells in mouse model
protein:increased expression:lung (human)
DNA:mutations:multiple		 RGD PMID:24469836 PMID:31662324 PMID:32945371 PMID:29567880 PMID:32276600 More... RGD:151356906 RGD:151356915 RGD:151356931, RGD:151356750, RGD:151357000, RGD:151356758 NCBI chr 2:185,884,840...185,912,532
Ensembl chr 2:183,219,220...183,222,303 		JBrowse link
G Mdm2 MDM2 proto-oncogene ISO CTD Direct Evidence: marker/mechanism CTD PMID:19941079 PMID:21268124 NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Meox1 mesenchyme homeobox 1 ISO CTD Direct Evidence: therapeutic CTD PMID:34837450 NCBI chr10:87,318,668...87,338,169
Ensembl chr10:86,818,478...86,837,660 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase disease_progression ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:21623265 PMID:21815704 PMID:22787409 PMID:24688052 PMID:20519133 More... RGD:5133241, RGD:13434906, RGD:5133243, RGD:5133242 NCBI chr 4:46,756,823...46,864,041
Ensembl chr 4:45,790,791...45,897,876 		JBrowse link
G Mier3 MIER family member 3 ISO mRNA:decreased expression:lung RGD PMID:35117188 RGD:407571696 NCBI chr 2:45,021,167...45,049,745
Ensembl chr 2:43,287,916...43,316,136 		JBrowse link
G Mif macrophage migration inhibitory factor ISO RGD PMID:12576459 RGD:4891022 NCBI chr20:12,767,138...12,791,222
Ensembl chr20:12,790,902...12,799,504
Ensembl chr 4:12,790,902...12,799,504 		JBrowse link
G Mir107 microRNA 107 ISO mRNA:decreased expression:lung (human) RGD PMID:30280776 RGD:126925764 NCBI chr 1:241,750,418...241,750,504
Ensembl chr 1:232,337,767...232,337,853 		JBrowse link
G Mir126a microRNA 126a ISO CTD Direct Evidence: therapeutic CTD PMID:20097187 NCBI chr 3:29,813,150...29,813,267
Ensembl chr 3:9,415,063...9,415,180 		JBrowse link
G Mir136 microRNA 136 ameliorates ISO RNA:decreased expression:lung (human)
human cells in mouse model		 RGD PMID:31059060 PMID:34556984 RGD:153344623, RGD:153344608 NCBI chr 6:134,331,335...134,331,416
Ensembl chr 6:128,549,096...128,549,177 		JBrowse link
G Mir145 microRNA 145 ISO CTD Direct Evidence: therapeutic CTD PMID:20097187 NCBI chr18:57,369,983...57,370,070
Ensembl chr18:55,099,640...55,099,727 		JBrowse link
G Mir146a microRNA 146a ameliorates
severity		 ISO RGD PMID:27494902 PMID:27494902 RGD:151665165, RGD:151665165 NCBI chr10:28,349,996...28,350,090
Ensembl chr10:27,848,516...27,848,610 		JBrowse link
G Mir154 microRNA 154 treatment
disease_progression		 ISO human cells in mouse model
RNA:decreased expression:lung (human)		 RGD PMID:30780105 PMID:25846246 RGD:152995466, RGD:152995468 NCBI chr 6:134,574,352...134,574,435
Ensembl chr 6:128,752,947...128,753,030 		JBrowse link
G Mir193a microRNA 193a ameliorates ISO miRNA:decreased expression:lung (human)
human cells in mouse model		 RGD PMID:26655272 PMID:31205511 RGD:11085320, RGD:153344584 NCBI chr10:65,170,306...65,170,417
Ensembl chr10:64,672,343...64,672,454 		JBrowse link
G Mir205 microRNA 205 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21563230 NCBI chr13:107,564,535...107,564,642
Ensembl chr13:105,035,878...105,035,985 		JBrowse link
G Mir21 microRNA 21 disease_progression ISO RNA:increased expression:lung (human)
RNA:increased expression:blood serum (human)		 RGD PMID:20956945 PMID:20223231 PMID:25477028 PMID:22956424 PMID:33467964 More... RGD:41404697, RGD:152998901, RGD:152998899, RGD:152998889, RGD:152998886, RGD:152998885 NCBI chr10:71,902,600...71,902,691
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mir222 microRNA 222 disease_progression ISO RGD PMID:24955421 PMID:30233216 RGD:151708732, RGD:151708743 NCBI chr  X:6,022,621...6,022,723
Ensembl chr  X:3,428,904...3,429,006 		JBrowse link
G Mir223 microRNA 223 severity
treatment		 ISO RGD PMID:29615147 PMID:29615147 RGD:21408562, RGD:21408562 NCBI chr  X:65,151,383...65,151,492
Ensembl chr  X:61,141,887...61,141,996 		JBrowse link
G Mir29a microRNA 29a ISO CTD Direct Evidence: marker/mechanism CTD PMID:22048643 NCBI chr 4:60,617,955...60,618,042 JBrowse link
G Mir29b1 microRNA 29b-1 treatment ISO RGD PMID:23591808 RGD:13464324 NCBI chr 4:60,618,334...60,618,414
Ensembl chr 4:59,650,986...59,651,067 		JBrowse link
G Mir301a microRNA 301a ISO CTD Direct Evidence: marker/mechanism CTD PMID:35305058 NCBI chr10:72,422,599...72,422,698
Ensembl chr10:71,925,336...71,925,435 		JBrowse link
G Mir30c1 microRNA 30c-1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20889907 NCBI chr 5:139,634,455...139,634,543
Ensembl chr 5:134,349,237...134,349,325 		JBrowse link
G Mir31 microRNA 31 ISO miRNA:increased expression:sputum (human) RGD PMID:27777637 RGD:152998954 NCBI chr 5:108,714,849...108,714,954 JBrowse link
G Mir346 microRNA 346 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27777383 NCBI chr16:10,224,300...10,224,397
Ensembl chr16:10,218,118...10,218,215 		JBrowse link
G Mir377 microRNA 377 ISO miRNA:decreased expression:lung RGD PMID:27874949 RGD:13464321 NCBI chr 6:128,755,051...128,755,122 JBrowse link
G Mir381 microRNA 381 treatment ISO RGD PMID:29287202 RGD:13464271 NCBI chr 6:134,562,381...134,562,441 JBrowse link
G Mir484 microRNA 484 disease_progression ISO mRNA:increased expression:lung
mRNA:decreased expression:lung		 RGD PMID:28982084 PMID:28982084 RGD:13703106, RGD:13703106 NCBI chr10:1,394,905...1,394,981
Ensembl chr10:887,684...887,760 		JBrowse link
G Mir497 microRNA 497 ISO miRNA:decreased expression:lung RGD PMID:31115562 RGD:126925181 NCBI chr10:55,450,171...55,450,239
Ensembl chr10:54,951,505...54,951,584 		JBrowse link
G Mir665 microRNA 665 disease_progression ISO associated with metastasis; mRNA:increased expression:lung (human) RGD PMID:32269632 PMID:32269632 RGD:151361291, RGD:151361291 NCBI chr 6:134,321,679...134,321,772
Ensembl chr 6:128,539,440...128,539,533 		JBrowse link
G Mir671 microRNA 671 severity ISO RGD PMID:30664171 RGD:151665171 NCBI chr 4:11,473,194...11,473,274
Ensembl chr 4:10,580,738...10,580,835 		JBrowse link
G Mki67 marker of proliferation Ki-67 ameliorates ISO human cells in mouse model RGD PMID:31205511 RGD:153344584 NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:190,496,319...190,522,762 		JBrowse link
G Mlh1 mutL homolog 1 severity ISO RGD PMID:32211850 PMID:18370958 RGD:126848780, RGD:126848801 NCBI chr 8:120,074,871...120,112,109
Ensembl chr 8:111,196,468...111,233,617 		JBrowse link
G Mmp1 matrix metallopeptidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20471133 NCBI chr 8:12,943,453...12,963,966
Ensembl chr 8:4,658,588...4,679,097 		JBrowse link
G Mmp11 matrix metallopeptidase 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10741738 NCBI chr20:12,730,284...12,739,067
Ensembl chr20:12,730,836...12,739,628 		JBrowse link
G Mmp2 matrix metallopeptidase 2 severity ISO protein:increased expression, increased activity:lung RGD PMID:17143501 RGD:5130739 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp7 matrix metallopeptidase 7 ISO mRNA:increased expression:lung RGD PMID:19596921 RGD:5129528 NCBI chr 8:13,133,043...13,140,761
Ensembl chr 8:4,848,186...4,855,902 		JBrowse link
G Mmp9 matrix metallopeptidase 9 disease_progression ISO protein:increased expression:serum
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:21789004 PMID:20704821 RGD:5129215 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Ms4a1 membrane spanning 4-domains A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22514692 NCBI chr 1:217,331,274...217,351,934
Ensembl chr 1:207,906,374...207,918,512 		JBrowse link
G Msh2 mutS homolog 2 treatment ISO protein:decreased expression:lung
DNA:SNP: :rs6544991 (human)		 RGD PMID:32211850 PMID:20458443 PMID:16783774 PMID:20145178 PMID:28093084 RGD:126848780, RGD:126848800, RGD:126848791, RGD:126848789, RGD:126848786 NCBI chr 6:12,567,368...12,626,534
Ensembl chr 6:6,813,795...6,872,938 		JBrowse link
G Msh3 mutS homolog 3 treatment ISO DNA:SNPs: :rs6151627, rs6151670, rs7709909 (human) RGD PMID:28093084 RGD:126848786 NCBI chr 2:25,179,400...25,320,857 JBrowse link
G Msh5 mutS homolog 5 treatment ISO DNA:SNPs: :rs805304, rs707939 (human) RGD PMID:28093084 RGD:126848786 NCBI chr20:3,779,180...3,797,996
Ensembl chr20:3,776,942...3,793,336 		JBrowse link
G Mt3 metallothionein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17043644 NCBI chr19:10,854,676...10,856,080
Ensembl chr19:10,848,755...10,850,158 		JBrowse link
G Mtor mechanistic target of rapamycin kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:24688052 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor disease_progression ISO protein:increased expression:lung (human)
DNA:hypomethylation:promoter (human)		 RGD PMID:31432177 PMID:32010578 RGD:150519919, RGD:150524328 NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Nat1 N-acetyltransferase 1 susceptibility ISO DNA:polymorphism: : RGD PMID:18258609 RGD:4140950 NCBI chr16:26,984,882...27,005,194
Ensembl chr16:22,208,194...22,238,520 		JBrowse link
G Ncaph non-SMC condensin I complex, subunit H ISO protein:decreased expression:lung (human) RGD PMID:32945371 RGD:151356931 NCBI chr 3:134,825,271...134,852,502
Ensembl chr 3:114,371,941...114,399,180 		JBrowse link
G Ncoa2 nuclear receptor coactivator 2 ISO DNA:SNPs:introns: (rs2926702, rs11993276) (human) RGD PMID:23144319 RGD:153002581 NCBI chr 5:10,618,712...10,852,776
Ensembl chr 5:5,835,706...6,067,451 		JBrowse link
G Ncoa3 nuclear receptor coactivator 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20852035 NCBI chr 3:175,157,824...175,237,831
Ensembl chr 3:154,738,581...154,818,594 		JBrowse link
G Ndc80 NDC80 kinetochore complex component disease_progression ISO RGD PMID:17079454 RGD:28867236 NCBI chr 9:118,853,806...118,887,582
Ensembl chr 9:111,407,191...111,440,924 		JBrowse link
G Ndrg1 N-myc downstream regulated 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15341671 NCBI chr 7:100,573,526...100,614,902
Ensembl chr 7:98,684,487...98,725,880 		JBrowse link
G Nek2 NIMA-related kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28509438 NCBI chr13:105,936,809...105,950,054
Ensembl chr13:103,405,819...103,419,051 		JBrowse link
G Nf1 neurofibromin 1 ISO mRNA:increased expression:lung (human) RGD PMID:30280776 RGD:126925764 NCBI chr10:64,803,986...65,037,086
Ensembl chr10:64,306,301...64,536,658 		JBrowse link
G Nf2 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor ISO RGD PMID:21743150 RGD:150530639 NCBI chr14:83,850,894...83,934,263
Ensembl chr14:79,627,399...79,710,667 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22684020 PMID:26482881 PMID:33148531 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 susceptibility ISO DNA:polymorphism:rs28362491(human)
protein:increased expression:nucleus		 RGD PMID:26221384 PMID:17899287 RGD:13793390, RGD:13793391 NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nnat neuronatin ISO CTD Direct Evidence: marker/mechanism CTD PMID:17043644 NCBI chr 3:166,646,373...166,648,845
Ensembl chr 3:146,226,407...146,228,834 		JBrowse link
G Notch3 notch receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21994468 NCBI chr 7:11,783,550...11,834,585
Ensembl chr 7:11,133,706...11,184,025 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 disease_progression ISO DNA:polymorphism: :
CTD Direct Evidence: marker/mechanism
DNA:polymorphism:cds: 609 C>T (human)		 CTD
RGD		 PMID:9865924 PMID:21479364 PMID:21479364 PMID:19596483 RGD:5133265, RGD:5133268 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 disease_progression ISO protein:increased expression:lung RGD PMID:16806572 RGD:4892333 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Nras NRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Non-small cell lung carcinoma ClinVar PMID:1654209 PMID:6587382 PMID:12727991 PMID:14508525 PMID:18633438 More... NCBI chr 2:193,271,399...193,282,023
Ensembl chr 2:190,582,918...190,591,626 		JBrowse link
G Nrp1 neuropilin 1 disease_progression ISO DNA, protein:CNVs, increased expression:lung RGD PMID:25561764 RGD:126925188 NCBI chr19:73,256,557...73,411,705
Ensembl chr19:56,359,455...56,513,633 		JBrowse link
G Nsd2 nuclear receptor binding SET domain protein 2 ISO mRNA:increased expression:lung (human) RGD PMID:34551195 RGD:155663369 NCBI chr14:81,057,727...81,135,866
Ensembl chr14:76,835,637...76,913,641 		JBrowse link
G Nuf2 NUF2 component of NDC80 kinetochore complex disease_progression ISO RGD PMID:17079454 RGD:28867236 NCBI chr13:84,226,448...84,290,957
Ensembl chr13:81,693,598...81,722,766 		JBrowse link
G Oip5-as1 OIP5 antisense RNA 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35044041 NCBI chr 3:106,578,309...106,591,845 JBrowse link
G Osmr oncostatin M receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:15496427 NCBI chr 2:57,634,517...57,688,802
Ensembl chr 2:55,907,132...55,961,262 		JBrowse link
G Oxtr oxytocin receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:17043644 NCBI chr 4:147,154,374...147,171,723
Ensembl chr 4:145,599,561...145,614,674 		JBrowse link
G Paox polyamine oxidase susceptibility ISO DNA:SNPs: :rs7316, rs1046175(human) RGD PMID:31016788 RGD:151667418 NCBI chr 1:204,349,326...204,358,140
Ensembl chr 1:194,903,273...194,928,504 		JBrowse link
G Pbrm1 polybromo 1 disease_progression ISO RGD PMID:32195359 RGD:150340625 NCBI chr16:6,219,933...6,319,336
Ensembl chr16:6,213,300...6,311,780 		JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 disease_progression ISO mRNA:increased expression:blood serum RGD PMID:25064732 RGD:13503320 NCBI chr10:13,610,000...13,687,226
Ensembl chr10:13,105,498...13,174,623 		JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 treatment ISO human cells in mouse model RGD PMID:23632475 RGD:150404268 NCBI chr10:92,090,263...92,152,002
Ensembl chr10:91,590,521...91,652,116 		JBrowse link
G Pgam1 phosphoglycerate mutase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17094902 NCBI chr 1:250,673,152...250,680,762
Ensembl chr 1:240,723,920...240,738,452 		JBrowse link
G Phgdh phosphoglycerate dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:26482881 NCBI chr 2:188,595,700...188,624,789
Ensembl chr 2:185,906,966...185,935,944 		JBrowse link
G Phlda2 pleckstrin homology-like domain, family A, member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15496427 NCBI chr 1:208,126,302...208,127,241
Ensembl chr 1:198,696,897...198,697,836 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha ISO ClinVar Annotator: match by term: Non-small cell lung cancer | ClinVar Annotator: match by term: Non-small cell lung carcinoma ClinVar
RGD		 PMID:15016963 PMID:15520168 PMID:15608678 PMID:15930273 PMID:17376864 More... RGD:5133243, RGD:5133242 NCBI chr 2:117,103,643...117,177,411
Ensembl chr 2:115,174,984...115,249,032 		JBrowse link
G Plau plasminogen activator, urokinase ISO RGD PMID:20937265 RGD:4892055 NCBI chr15:3,505,485...3,511,987
Ensembl chr15:3,456,232...3,462,775 		JBrowse link
G Plbd1 phospholipase B domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15496427 NCBI chr 4:169,472,983...169,529,277
Ensembl chr 4:169,472,983...169,529,277 		JBrowse link
G Plcg1 phospholipase C, gamma 1 treatment ISO human cell line in a mouse model RGD PMID:33928024 RGD:151665816 NCBI chr 3:169,805,299...169,836,040
Ensembl chr 3:149,385,587...149,416,330 		JBrowse link
G Pole DNA polymerase epsilon, catalytic subunit ameliorates ISO DNA:mutations:multiple (human) RGD PMID:32433714 RGD:151347639 NCBI chr12:52,005,155...52,053,761
Ensembl chr12:46,345,420...46,393,939 		JBrowse link
G Ppia peptidylprolyl isomerase A ISO CTD Direct Evidence: marker/mechanism CTD PMID:17094902 NCBI chr14:85,491,223...85,496,884
Ensembl chr14:81,275,091...81,299,601 		JBrowse link
G Pramex1 PRAME like, X-linked 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16179254 NCBI chr  X:102,862,457...102,867,725
Ensembl chr  X:98,569,415...98,572,096 		JBrowse link
G Prdm14 PR/SET domain 14 disease_progression ISO DNA:hypermethylation RGD PMID:23690269 PMID:27777637 RGD:150530468, RGD:152998954 NCBI chr 5:10,864,137...10,876,666
Ensembl chr 5:6,082,442...6,092,712 		JBrowse link
G Prdx1 peroxiredoxin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17094902 NCBI chr 5:135,383,906...135,399,504
Ensembl chr 5:130,147,204...130,162,856 		JBrowse link
G Prex2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 ISO mRNA:increased expression:lung (human) RGD PMID:31711559 RGD:151665187 NCBI chr 5:12,720,683...13,036,077
Ensembl chr 5:7,942,573...8,253,068 		JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 treatment ISO human cells in mouse model RGD PMID:23632475 RGD:150404268 NCBI chr 2:55,967,766...56,003,450
Ensembl chr 2:54,240,137...54,275,978 		JBrowse link
G Prkcb protein kinase C, beta ISO DNA:hypermethylation:promoter:lung RGD PMID:28422739 RGD:13503321 NCBI chr 1:186,263,397...186,594,743
Ensembl chr 1:176,832,226...177,163,536 		JBrowse link
G Prr13 proline rich 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21157449 NCBI chr 7:133,592,511...133,595,817
Ensembl chr 7:133,592,490...133,601,005 		JBrowse link
G Psat1 phosphoserine aminotransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26482881 NCBI chr 1:222,623,553...222,646,187
Ensembl chr 1:213,196,709...213,218,682 		JBrowse link
G Pten phosphatase and tensin homolog ISO mRNA:decreased expression:lung (human)
DNA:loss of heterozygosity:cds: (human)		 RGD PMID:20951313 PMID:20223231 PMID:22956424 PMID:9458098 RGD:5133242, RGD:152998901, RGD:152998889, RGD:12832745 NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Ptges prostaglandin E synthase severity ISO protein:increased expression:lung RGD PMID:20592629 RGD:5135302 NCBI chr 3:34,575,643...34,586,987 JBrowse link
G Ptgis prostaglandin I2 synthase severity ISO protein:decreased expression:lung (human) RGD PMID:16314486 RGD:151347842 NCBI chr 3:176,347,589...176,383,251
Ensembl chr 3:155,916,412...155,965,451 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 severity ISO protein:increased expression:lung
DNA:SNP: :929G>C(human)		 RGD PMID:20592629 PMID:20016751 RGD:5135302, RGD:5135471 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Pthlh parathyroid hormone-like hormone ISO CTD Direct Evidence: therapeutic CTD PMID:17676588 NCBI chr 4:181,919,400...181,930,454
Ensembl chr 4:180,188,792...180,199,847 		JBrowse link
G Ptprb protein tyrosine phosphatase, receptor type, B disease_progression ISO human cells in mouse model
mRNA:decreased expression:lung (human)		 RGD PMID:27314562 PMID:27314562 RGD:151361281, RGD:151361281 NCBI chr 7:53,816,197...53,920,760
Ensembl chr 7:51,930,015...52,034,748 		JBrowse link
G Pxn paxillin ISO CTD Direct Evidence: marker/mechanism CTD PMID:21159652 NCBI chr12:46,721,546...46,768,706
Ensembl chr12:41,060,791...41,107,931 		JBrowse link
G Pycard PYD and CARD domain containing ISO CTD Direct Evidence: marker/mechanism CTD PMID:16778195 NCBI chr 1:192,032,124...192,033,419
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Rad21 RAD21 cohesin complex component susceptibility
exacerbates		 ISO DNA:SNP:intron: (rs1374297) (human)
mRNA:increased expression:lung (human)		 RGD PMID:32178590 PMID:28977903 RGD:150520031, RGD:150520036 NCBI chr 7:85,177,715...85,204,657
Ensembl chr 7:83,287,870...83,314,817 		JBrowse link
G Rad52 RAD52 homolog, DNA repair protein susceptibility ISO DNA:SNPs,haplotype:multiple RGD PMID:32401173 RGD:151660355 NCBI chr 4:154,778,320...154,802,002
Ensembl chr 4:153,106,062...153,128,207 		JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16862215 NCBI chr 4:150,352,158...150,412,813
Ensembl chr 4:148,679,530...148,740,317 		JBrowse link
G Rarb retinoic acid receptor, beta ISO DNA:hypermethylation:lung RGD PMID:23599765 PMID:18349282 RGD:13503323, RGD:13503324 NCBI chr15:10,837,252...11,482,037
Ensembl chr15:8,406,492...9,051,288 		JBrowse link
G Rassf1 Ras association domain family member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18337602 NCBI chr 8:117,103,665...117,114,805
Ensembl chr 8:108,225,023...108,236,164 		JBrowse link
G Rassf5 Ras association domain family member 5 ISO RGD PMID:20434789 RGD:13503325 NCBI chr13:45,189,768...45,255,277
Ensembl chr13:42,637,549...42,703,024 		JBrowse link
G Rb1 RB transcriptional corepressor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16862215 NCBI chr15:54,780,858...54,911,989
Ensembl chr15:48,371,296...48,502,302 		JBrowse link
G Rbm7 RNA binding motif protein 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15496427 NCBI chr 8:48,831,894...48,838,399
Ensembl chr 8:48,831,894...48,838,411 		JBrowse link
G Reck reversion-inducing-cysteine-rich protein with kazal motifs ISO CTD Direct Evidence: marker/mechanism CTD PMID:17233834 NCBI chr 5:62,898,717...62,965,274
Ensembl chr 5:58,102,981...58,169,502 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit ISO RGD PMID:16287968 RGD:2298765 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Rheb Ras homolog, mTORC1 binding ISO CTD Direct Evidence: marker/mechanism CTD PMID:20554106 NCBI chr 4:11,012,173...11,053,860
Ensembl chr 4:10,279,370...10,320,160 		JBrowse link
G Rnf168 ring finger protein 168 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34873829 NCBI chr11:81,991,352...82,013,306
Ensembl chr11:68,486,321...68,508,277 		JBrowse link
G Robo1 roundabout guidance receptor 1 IEP mRNA:altered expression:lung RGD PMID:15264215 RGD:2314868 NCBI chr11:24,067,869...25,108,694
Ensembl chr11:10,580,908...11,620,203 		JBrowse link
G Ros1 ROS proto-oncogene 1 , receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:22215748 PMID:22585869 PMID:22617245 PMID:22919003 NCBI chr20:31,975,328...32,126,675
Ensembl chr20:31,432,637...31,583,865 		JBrowse link
G Rrad RRAD, Ras related glycolysis inhibitor and calcium channel regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:17195088 NCBI chr19:360,581...363,874
Ensembl chr19:354,198...357,417 		JBrowse link
G Rrm1 ribonucleotide reductase catalytic subunit M1 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:21496433 PMID:19002265 RGD:127229933 NCBI chr 1:166,235,904...166,260,206
Ensembl chr 1:156,823,960...156,848,261 		JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 treatment ISO RGD PMID:19002265 RGD:127229933 NCBI chr 6:47,044,755...47,075,370
Ensembl chr 6:41,340,557...41,346,773 		JBrowse link
G Runx1 RUNX family transcription factor 1 disease_progression ISO mRNA:alternative form:lung RGD PMID:26685324 RGD:126779572 NCBI chr11:45,325,778...45,560,300
Ensembl chr11:31,843,764...32,074,542 		JBrowse link
G Runx2 RUNX family transcription factor 2 ISO human cells in mouse model RGD PMID:30780105 RGD:152995466 NCBI chr 9:23,661,278...23,990,248
Ensembl chr 9:16,167,482...16,492,167 		JBrowse link
G Runx3 RUNX family transcription factor 3 ISO DNA:hypermethylation:promoter RGD PMID:18349282 RGD:13503324 NCBI chr 5:152,644,270...152,702,835
Ensembl chr 5:147,360,994...147,419,156 		JBrowse link
G Rxrg retinoid X receptor gamma ISO DNA:hypermethylation:promoter RGD PMID:20113835 RGD:13503326 NCBI chr13:82,276,330...82,318,097
Ensembl chr13:79,743,563...79,785,167 		JBrowse link
G Scgb3a2 secretoglobin, family 3A, member 2 ISO RGD PMID:20466451 RGD:5147390 NCBI chr18:36,183,745...36,186,667
Ensembl chr18:35,932,840...35,935,762 		JBrowse link
G Sdc4 syndecan 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22919003 NCBI chr 3:173,574,239...173,592,923
Ensembl chr 3:153,154,896...153,173,580 		JBrowse link
G Sdha succinate dehydrogenase complex flavoprotein subunit A susceptibility ISO DNA:SNP: 3'utr (rs13173911) (human) RGD PMID:25576295 RGD:150340558 NCBI chr 1:30,764,553...30,789,523
Ensembl chr 1:28,940,164...28,961,535 		JBrowse link
G Sdhc succinate dehydrogenase complex subunit C exacerbates ISO DNA:SNP: 3'utr (rs12064957) (human) RGD PMID:25576295 RGD:150340558 NCBI chr13:86,077,133...86,098,025
Ensembl chr13:83,544,652...83,566,253 		JBrowse link
G Selenos selenoprotein S ISO CTD Direct Evidence: marker/mechanism CTD PMID:20471133 NCBI chr 1:129,070,240...129,080,007
Ensembl chr 1:119,659,751...119,669,833 		JBrowse link
G Serpinf1 serpin family F member 1 ISO protein:increased expression:serum, pleural effusion (human) RGD PMID:20230924 RGD:27226710 NCBI chr10:60,748,504...60,760,898
Ensembl chr10:60,249,708...60,262,646 		JBrowse link
G Sftpb surfactant protein B susceptibility ISO DNA:SNPs: :rs7316, rs9752 (human) RGD PMID:31016788 RGD:151667418 NCBI chr 4:105,917,495...105,926,631
Ensembl chr 4:104,359,396...104,368,436 		JBrowse link
G Sftpd surfactant protein D disease_progression ISO RGD PMID:20401612 RGD:4143490 NCBI chr16:17,080,575...17,093,047
Ensembl chr16:17,046,483...17,059,927 		JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26482881 NCBI chr 7:65,244,247...65,249,580
Ensembl chr 7:63,358,961...63,364,236 		JBrowse link
G Slc22a18 solute carrier family 22, member 18 disease_progression ISO mRNA:increased expression:lung (human)
protein:increased expression:lung (human)		 RGD PMID:25498886 PMID:22237119 RGD:150557424, RGD:150557425 NCBI chr 1:208,100,032...208,124,382
Ensembl chr 1:198,671,731...198,694,975 		JBrowse link
G Slc22a22 solute carrier family 22 member 22 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr 7:90,610,007...90,639,718
Ensembl chr 7:88,720,427...88,750,111 		JBrowse link
G Slc34a2 solute carrier family 34 member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22617245 PMID:22919003 NCBI chr14:57,910,931...57,930,236
Ensembl chr14:57,910,480...57,930,436 		JBrowse link
G Slc3a2 solute carrier family 3 member 2 disease_progression
severity
sexual_dimorphism		 ISO DNA:SNP:5'utr: (rs105929) (human)
protein:increased expression:lung (human)		 RGD PMID:22110199 PMID:24782339 PMID:25084765 RGD:151361206, RGD:152995443, RGD:152995442 NCBI chr 1:215,033,601...215,048,064
Ensembl chr 1:205,604,468...205,618,931 		JBrowse link
G Slc7a5 solute carrier family 7 member 5 disease_progression
treatment		 ISO RGD PMID:21187458 PMID:22110199 RGD:151361159, RGD:151361206 NCBI chr19:66,843,808...66,872,412
Ensembl chr19:49,935,220...49,963,823 		JBrowse link
G Smad3 SMAD family member 3 ISO protein:increased expression:lung (human) RGD PMID:25375657 RGD:11074609 NCBI chr 8:73,022,204...73,132,324
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
G Smarca4 SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4 ISO RGD PMID:15287030 RGD:2302526 NCBI chr 8:28,438,370...28,535,071
Ensembl chr 8:20,167,717...20,258,975 		JBrowse link
G Snap47 synaptosome associated protein 47 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34664776 NCBI chr10:44,692,430...44,733,986
Ensembl chr10:44,191,218...44,234,424 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 disease_progression ISO RGD PMID:31910343 RGD:150573699 NCBI chr10:5,389,574...5,391,265
Ensembl chr10:4,882,560...4,884,383 		JBrowse link
G Socs2 suppressor of cytokine signaling 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35305058 NCBI chr 7:31,890,564...31,932,092
Ensembl chr 7:30,008,578...30,043,548 		JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11731445 PMID:17094902 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sox30 SRY-box transcription factor 30 disease_progression ISO RGD PMID:32443323 RGD:151660331 NCBI chr10:30,918,707...30,948,415
Ensembl chr10:30,418,473...30,446,453 		JBrowse link
G Sox4 SRY-box transcription factor 4 severity ISO RGD PMID:16052521 RGD:153297793 NCBI chr17:35,876,298...35,881,004
Ensembl chr17:35,667,537...35,673,665 		JBrowse link
G Spop speckle type BTB/POZ protein ameliorates ISO mRNA, protein:increased expression:lung (human) RGD PMID:28927035 RGD:153298923 NCBI chr10:80,854,890...80,935,781
Ensembl chr10:80,358,124...80,483,955 		JBrowse link
G Spp1 secreted phosphoprotein 1 ISO RGD PMID:16533775 RGD:1581361 NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
G Srsf1 serine and arginine rich splicing factor 1 severity ISO protein:increased expression:lung (human) RGD PMID:20682707 PMID:23071587 RGD:11038729, RGD:150429662 NCBI chr10:73,335,519...73,342,549
Ensembl chr10:72,839,274...72,845,336 		JBrowse link
G Srsf2 serine and arginine rich splicing factor 2 ISO protein:increased expression:lung epithelium,nucleus RGD PMID:23071587 RGD:150429662 NCBI chr10:102,550,962...102,554,200
Ensembl chr10:102,052,314...102,055,338 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 severity ISO CTD Direct Evidence: marker/mechanism
protein:increased phosphorylation:lung (human)		 CTD
RGD		 PMID:21549414 PMID:22977534 RGD:152023747 NCBI chr10:86,311,528...86,363,513
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Stat5b signal transducer and activator of transcription 5B disease_progression ISO mRNA,protein:increased expression:lung (human) RGD PMID:25137041 RGD:153298930 NCBI chr10:86,205,148...86,276,178
Ensembl chr10:85,705,670...85,775,668 		JBrowse link
G Stim1 stromal interaction molecule 1 ISO mRNA:increased expression:blood plasma (human) RGD PMID:32184656 RGD:152995359 NCBI chr 1:166,067,450...166,230,733
Ensembl chr 1:156,656,013...156,818,363 		JBrowse link
G Syp synaptophysin ISO CTD Direct Evidence: marker/mechanism CTD PMID:21595568 NCBI chr  X:17,521,348...17,536,449
Ensembl chr  X:14,849,444...14,864,745 		JBrowse link
G Tab2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 ISO mRNA:increased expression:lung (human) RGD PMID:34551195 RGD:155663369 NCBI chr 1:4,195,400...4,245,485
Ensembl chr 1:2,375,490...2,424,756 		JBrowse link
G Tent5a terminal nucleotidyltransferase 5A susceptibility ISO DNA:repeats: : RGD PMID:25884493 RGD:14390136 NCBI chr 8:86,222,294...86,229,045
Ensembl chr 8:86,225,357...86,229,045 		JBrowse link
G Tert telomerase reverse transcriptase disease_progression ISO CTD Direct Evidence: marker/mechanism
DNA:SNP: :rs2736098(human)
DNA:SNPs, haplotype: :rs2853669,rs2736108(human)		 CTD
RGD		 PMID:21252717 PMID:24679952 PMID:27982019 RGD:150530644, RGD:150530632 NCBI chr 1:31,465,766...31,488,650
Ensembl chr 1:29,637,506...29,659,561 		JBrowse link
G Tes testin LIM domain protein ameliorates ISO RGD PMID:28000866 RGD:597621667 NCBI chr 4:46,331,257...46,369,782
Ensembl chr 4:45,365,285...45,403,829 		JBrowse link
G Tet2 tet methylcytosine dioxygenase 2 ISO DNA:mutations:multiple RGD PMID:32554069 RGD:150429694 NCBI chr 2:224,662,654...224,746,819
Ensembl chr 2:221,988,645...222,072,534 		JBrowse link
G Tgfa transforming growth factor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:16230376 NCBI chr 4:120,175,549...120,258,342
Ensembl chr 4:118,618,269...118,700,894 		JBrowse link
G Thbd thrombomodulin disease_progression ISO RGD PMID:20607726 RGD:5685035 NCBI chr 3:156,316,526...156,320,178
Ensembl chr 3:135,862,835...135,867,193 		JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 disease_progression ISO RGD PMID:30233216 RGD:151708743 NCBI chr 7:19,408,539...19,459,558
Ensembl chr 7:17,521,919...17,571,839 		JBrowse link
G Tk1 thymidine kinase 1 ISO protein:increased expression:serum (human) RGD PMID:15583816 RGD:2317237 NCBI chr10:103,533,449...103,544,818
Ensembl chr10:103,031,521...103,046,920 		JBrowse link
G Tlr9 toll-like receptor 9 ISO mRNA, protein:increased expression:tumor (human) RGD PMID:15631627 RGD:5130185 NCBI chr 8:115,743,407...115,747,523
Ensembl chr 8:106,864,680...106,868,796 		JBrowse link
G Tmem135 transmembrane protein 135 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr 1:152,418,929...152,692,405
Ensembl chr 1:143,006,344...143,221,171 		JBrowse link
G Tnf tumor necrosis factor ISO DNA:SNPs: :
protein:increased expression:lung		 RGD PMID:19505916 PMID:9669810 RGD:4142793, RGD:4143264 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A disease_progression
severity		 ISO protein:increased expression:serum (human)
DNA:snp:5' utr:g.-329G>T rs4149570 (human)		 RGD PMID:20824709 PMID:20422457 RGD:5131156, RGD:5131202 NCBI chr 4:159,837,119...159,849,817
Ensembl chr 4:158,150,820...158,163,591 		JBrowse link
G Tp53 tumor protein p53 treatment ISO human cells in mouse model
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:17290066 PMID:23435014 PMID:24688052 PMID:30381462 PMID:20951313 More... RGD:5133242, RGD:150404268 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr 3:128,620,320...128,724,716
Ensembl chr 3:108,169,980...108,269,822 		JBrowse link
G Tp73 tumor protein p73 treatment ISO DNA:SNP:intron: (rs3765701) (human) RGD PMID:21965272 RGD:151347589 NCBI chr 5:169,903,801...169,988,075
Ensembl chr 5:164,621,377...164,681,128 		JBrowse link
G Trmt11 tRNA methyltransferase 11 homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:30705370 NCBI chr 1:28,873,361...28,928,679
Ensembl chr 1:27,054,420...27,201,610 		JBrowse link
G Ttr transthyretin disease_progression ISO protein:decreased expression:blood serum (human) RGD PMID:31031974 RGD:151664739 NCBI chr18:12,216,684...12,225,972
Ensembl chr18:11,943,789...11,951,008 		JBrowse link
G Tymp thymidine phosphorylase ISO RGD PMID:19671868 RGD:2325156 NCBI chr 7:122,318,396...122,323,716
Ensembl chr 7:120,438,770...120,443,874
Ensembl chr 7:120,438,770...120,443,874 		JBrowse link
G Ubr5 ubiquitin protein ligase E3 component n-recognin 5 exacerbates ISO circRNA:decreased expression:lung (human) RGD PMID:29944885 RGD:151665198 NCBI chr 7:71,000,197...71,109,841
Ensembl chr 7:69,116,761...69,224,903 		JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17094902 NCBI chr14:41,838,859...41,849,743
Ensembl chr14:41,485,031...41,495,590 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 treatment ISO DNA:repeat:promoter:(TA) RGD PMID:16636344 RGD:10769339 NCBI chr 9:96,249,143...96,256,264
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Vegfa vascular endothelial growth factor A disease_progression ISO CTD Direct Evidence: marker/mechanism
protein:inctreased expression:lung (human)
protein:increased expression:plasma		 CTD
RGD		 PMID:15956251 PMID:22977534 PMID:21481963 RGD:152023747, RGD:126925199 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Wee1 WEE1 G2 checkpoint kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:34664776 NCBI chr 1:173,605,609...173,632,450
Ensembl chr 1:164,174,779...164,197,688 		JBrowse link
G Wrap53 WD repeat containing, antisense to TP53 disease_progression ISO RNA:increased expression:lung
DNA:hypermethylation:promoter		 RGD PMID:31281482 PMID:30344734 RGD:21081513, RGD:21081519 NCBI chr10:54,780,873...54,797,919
Ensembl chr10:54,282,105...54,298,929 		JBrowse link
G Xpc XPC complex subunit, DNA damage recognition and repair factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:27777383 NCBI chr 4:125,550,833...125,578,084
Ensembl chr 4:123,993,666...124,021,010 		JBrowse link
G Xpo1 exportin 1 ameliorates
treatment		 ISO human cell line in a mouse model RGD PMID:31113936 PMID:24946002 RGD:151665798, RGD:151667438 NCBI chr14:101,434,450...101,476,705
Ensembl chr14:97,233,270...97,275,498 		JBrowse link
G Xpo5 exportin 5 severity ISO DNA:snp, haplotype:3' utr:c.*659A>C (rs11077) (human) RGD PMID:21799879 RGD:11041736 NCBI chr 9:22,237,760...22,275,745
Ensembl chr 9:14,740,182...14,778,171 		JBrowse link
G Xrcc1 X-ray repair cross complementing 1 treatment
severity
susceptibility		 ISO DNA:missense mutation:p.R399Q (human)
DNA:SNP:3'utr: (rs25487) (human)
DNA:missense mutation:cds: p.R194W (human)
DNA:missense mutations:cds:p.R194W, p.R399Q (human)		 RGD PMID:23549037 PMID:15301704 PMID:24446315 PMID:26345972 PMID:24782167 More... RGD:127229950, RGD:151347427, RGD:11097268, RGD:11251107, RGD:151347410, RGD:151347402, RGD:151347175, RGD:11538163, RGD:151232297, RGD:151232295 NCBI chr 1:89,268,721...89,296,619
Ensembl chr 1:80,141,207...80,168,701 		JBrowse link
G Zfhx3 zinc finger homeobox 3 ameliorates
exacerbates		 ISO DNA:mutations:multiple (human)
mRNA:decreased expression:lung (human)		 RGD PMID:32653938 PMID:23144151 RGD:151361163, RGD:151361164 NCBI chr19:52,789,146...53,795,664
Ensembl chr19:36,630,254...36,881,771 		JBrowse link
G Zfp462 zinc finger protein 462 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29059373 NCBI chr 5:74,465,383...74,606,020
Ensembl chr 5:69,670,328...69,810,327 		JBrowse link
lung non-squamous non-small cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Daxx death-domain associated protein exacerbates ISO protein:decreased expression:lung (human) RGD PMID:28004751 RGD:152025202 NCBI chr20:4,971,973...4,978,062
Ensembl chr20:4,970,092...4,975,843 		JBrowse link
G Tnik TRAF2 and NCK interacting kinase ISO mRNA,protein:increased expression:lung RGD PMID:25250715 PMID:25250715 RGD:151347838, RGD:151347838 NCBI chr 2:113,112,937...113,511,341
Ensembl chr 2:111,184,387...111,580,750 		JBrowse link
lung pleomorphic carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc3a2 solute carrier family 3 member 2 disease_progression ISO RGD PMID:30300664 RGD:151361288 NCBI chr 1:215,033,601...215,048,064
Ensembl chr 1:205,604,468...205,618,931 		JBrowse link
G Slc7a5 solute carrier family 7 member 5 disease_progression ISO RGD PMID:30300664 RGD:151361288 NCBI chr19:66,843,808...66,872,412
Ensembl chr19:49,935,220...49,963,823 		JBrowse link
lung sarcomatoid carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kras KRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Lung sarcomatoid carcinoma ClinVar PMID:8439212 PMID:15696205 PMID:17332249 PMID:17704260 PMID:19047918 More... NCBI chr 4:179,916,255...179,949,613 JBrowse link
G Msh6 mutS homolog 6 ISO ClinVar Annotator: match by term: Lung sarcomatoid carcinoma ClinVar NCBI chr 6:12,316,190...12,333,505
Ensembl chr 6:6,562,632...6,579,956 		JBrowse link
G Palb2 partner and localizer of BRCA2 ISO ClinVar Annotator: match by term: Lung sarcomatoid carcinoma ClinVar NCBI chr 1:186,096,312...186,120,284
Ensembl chr 1:176,665,076...176,688,990 		JBrowse link
G Pdgfra platelet derived growth factor receptor alpha ISO ClinVar Annotator: match by term: Lung sarcomatoid carcinoma ClinVar PMID:28492532 NCBI chr14:33,360,027...33,408,604
Ensembl chr14:33,005,839...33,054,335 		JBrowse link
G Rad50 RAD50 double strand break repair protein ISO ClinVar Annotator: match by term: Lung sarcomatoid carcinoma ClinVar PMID:16474176 PMID:24894818 PMID:25741868 PMID:26467025 PMID:26787654 More... NCBI chr10:38,310,147...38,362,100
Ensembl chr10:37,808,726...37,861,396 		JBrowse link
G Ros1 ROS proto-oncogene 1 , receptor tyrosine kinase ISO ClinVar Annotator: match by term: Lung sarcomatoid carcinoma ClinVar NCBI chr20:31,975,328...32,126,675
Ensembl chr20:31,432,637...31,583,865 		JBrowse link
G Tert telomerase reverse transcriptase ISO ClinVar Annotator: match by term: Lung sarcomatoid carcinoma ClinVar PMID:32923861 NCBI chr 1:31,465,766...31,488,650
Ensembl chr 1:29,637,506...29,659,561 		JBrowse link
G Tp53 tumor protein p53 ISO ClinVar Annotator: match by term: Lung sarcomatoid carcinoma ClinVar PMID:12826609 PMID:28492532 PMID:29979965 PMID:30224644 PMID:33251333 More... NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Vhl von Hippel-Lindau tumor suppressor ISO ClinVar Annotator: match by term: Lung sarcomatoid carcinoma ClinVar PMID:9829912 PMID:17006605 PMID:28492532 NCBI chr 4:148,328,099...148,334,992
Ensembl chr 4:146,772,468...146,779,377 		JBrowse link
lung small cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1b activin A receptor type 1B ISO RGD PMID:33880365 RGD:151665493 NCBI chr 7:134,164,987...134,208,389
Ensembl chr 7:132,286,275...132,329,673 		JBrowse link
G Adcy1 adenylate cyclase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr14:86,125,119...86,234,459
Ensembl chr14:81,911,099...82,028,969 		JBrowse link
G Apoa1 apolipoprotein A1 treatment ISO RGD PMID:26996551 RGD:11561502 NCBI chr 8:55,423,945...55,425,729
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G Apoc3 apolipoprotein C3 treatment ISO RGD PMID:26996551 RGD:11561502 NCBI chr 8:55,428,172...55,430,352
Ensembl chr 8:46,531,478...46,533,583 		JBrowse link
G Ascl1 achaete-scute family bHLH transcription factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26253517 NCBI chr 7:23,790,642...23,793,509
Ensembl chr 7:21,903,126...21,905,993 		JBrowse link
G Atm ATM serine/threonine kinase susceptibility ISO DNA:SNP:intron:(rs227060) (human) RGD PMID:28642860 RGD:150383339 NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Atrx ATRX, chromatin remodeler disease_progression ISO RGD PMID:31374064 PMID:29748005 RGD:127285382, RGD:127285383 NCBI chr  X:74,916,548...75,062,880
Ensembl chr  X:70,850,981...70,997,330 		JBrowse link
G Avp arginine vasopressin ISO CTD Direct Evidence: marker/mechanism CTD PMID:2832203 NCBI chr 3:138,246,544...138,248,522
Ensembl chr 3:117,793,457...117,795,425 		JBrowse link
G Axin2 axin 2 disease_progression ISO DNA:SNP::1386 C>T(human) RGD PMID:30346805 RGD:151356655 NCBI chr10:94,393,379...94,426,579
Ensembl chr10:93,899,245...93,926,231 		JBrowse link
G B2m beta-2 microglobulin ISO ClinVar Annotator: match by term: Small cell lung cancer | ClinVar Annotator: match by term: Small cell lung carcinoma ClinVar PMID:26619011 NCBI chr 3:129,549,236...129,555,354
Ensembl chr 3:109,095,729...109,101,766 		JBrowse link
G Bcl2 BCL2, apoptosis regulator susceptibility ISO DNA:SNP: :rs2279115(human) RGD PMID:26311051 RGD:13673911 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bclaf1 BCL2-associated transcription factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr 1:16,904,572...16,937,106
Ensembl chr 1:15,070,894...15,148,832 		JBrowse link
G Ccnd1 cyclin D1 disease_progression ISO DNA:snp:exon:c.870G>A (human) RGD PMID:29739297 RGD:13673912 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B ISO protein:increased expression:lung RGD PMID:9500468 RGD:13673920 NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cdyl chromodomain Y-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr17:29,188,697...29,409,805
Ensembl chr17:28,982,037...29,204,313 		JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit susceptibility ISO mRNA:increased expression:lung
DNA:SNP:cds:rs8040868(human)		 RGD PMID:20124469 PMID:22280835 RGD:150527851, RGD:151347453 NCBI chr 8:64,297,755...64,311,251
Ensembl chr 8:55,401,702...55,415,165 		JBrowse link
G Chrna5 cholinergic receptor nicotinic alpha 5 subunit ISO mRNA:increased expression:lung RGD PMID:20124469 RGD:150527851 NCBI chr 8:64,265,879...64,294,233
Ensembl chr 8:55,369,794...55,398,146 		JBrowse link
G Chrna9 cholinergic receptor nicotinic alpha 9 subunit susceptibility ISO DNA:SNPs:multiples: RGD PMID:22280835 RGD:151347453 NCBI chr14:42,588,948...42,595,669
Ensembl chr14:42,235,226...42,242,192 		JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit ISO mRNA:increased expression:lung RGD PMID:20124469 RGD:150527851 NCBI chr 8:64,312,644...64,333,319
Ensembl chr 8:55,418,313...55,437,027 		JBrowse link
G Ckb creatine kinase B ISO CTD Direct Evidence: marker/mechanism CTD PMID:2828370 NCBI chr 6:136,550,583...136,553,464
Ensembl chr 6:130,729,423...130,732,315 		JBrowse link
G Cntnap2 contactin associated protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr 4:75,109,358...77,366,258
Ensembl chr 4:74,109,472...76,362,027 		JBrowse link
G Col22a1 collagen type XXII alpha 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr 7:103,730,939...103,968,452
Ensembl chr 7:103,731,037...103,968,462 		JBrowse link
G Col4a2 collagen type IV alpha 2 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr16:84,749,672...84,885,520
Ensembl chr16:78,047,602...78,183,839 		JBrowse link
G Crebbp CREB binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941188 NCBI chr10:11,842,307...11,968,266
Ensembl chr10:11,335,953...11,461,888 		JBrowse link
G Csf1r colony stimulating factor 1 receptor exacerbates ISO protein:increased expression:lung (human) RGD PMID:1390197 RGD:150524305 NCBI chr18:56,834,152...56,860,804
Ensembl chr18:54,546,659...54,590,415 		JBrowse link
G Csf3 colony stimulating factor 3 ISO CTD Direct Evidence: therapeutic CTD PMID:9093707 NCBI chr10:84,157,485...84,159,860
Ensembl chr10:83,661,207...83,663,603 		JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 susceptibility ISO DNA:SNP:CDS: (rs6068816) (human) RGD PMID:31264381 RGD:151665340 NCBI chr 3:179,694,647...179,709,083
Ensembl chr 3:159,275,947...159,290,383 		JBrowse link
G Dip2c disco-interacting protein 2 homolog C ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr17:60,647,346...61,032,467
Ensembl chr17:60,649,065...61,032,305 		JBrowse link
G Dll4 delta like canonical Notch ligand 4 treatment IEP RGD PMID:33628824 RGD:155663482 NCBI chr 3:126,770,945...126,780,769
Ensembl chr 3:106,316,986...106,326,931 		JBrowse link
G Dnmt3b DNA methyltransferase 3 beta susceptibility ISO DNA:SNPs:promoter:-283T >C,-579G>T(human) RGD PMID:15528220 RGD:9589086 NCBI chr 3:162,590,777...162,629,313
Ensembl chr 3:142,130,592...142,169,124 		JBrowse link
G E2f1 E2F transcription factor 1 disease_progression
treatment		 ISO mRNA, protein:increased expression:lung RGD PMID:24755270 PMID:11313916 PMID:23792570 RGD:13464335, RGD:13464344, RGD:13464337 NCBI chr 3:163,524,739...163,535,563
Ensembl chr 3:143,049,478...143,075,361 		JBrowse link
G Eef2 eukaryotic translation elongation factor 2 ISO protein:increased expression:lung (human) RGD PMID:24589652 RGD:153297816 NCBI chr 7:9,183,836...9,196,255
Ensembl chr 7:8,533,116...8,559,183 		JBrowse link
G Egfr epidermal growth factor receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20837450 NCBI chr14:95,378,626...95,551,358
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Elavl2 ELAV like RNA binding protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr 5:105,960,872...106,086,463
Ensembl chr 5:105,960,875...106,109,097 		JBrowse link
G Ep300 E1A binding protein p300 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941188 NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088 		JBrowse link
G Epha7 Eph receptor A7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941188 NCBI chr 5:47,771,776...47,925,189
Ensembl chr 5:42,975,405...43,127,112 		JBrowse link
G Fat1 FAT atypical cadherin 1 ISO DNA:mutations:multiple (human) RGD PMID:31199602 RGD:150429733 NCBI chr16:53,909,759...54,029,175
Ensembl chr16:47,177,248...47,296,107 		JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941188 NCBI chr16:73,194,631...73,249,855
Ensembl chr16:66,494,042...66,547,350 		JBrowse link
G Foxa1 forkhead box A1 disease_progression ISO RGD PMID:22383183 RGD:151665760 NCBI chr 6:80,838,380...80,871,195
Ensembl chr 6:75,103,503...75,136,188 		JBrowse link
G Grik3 glutamate ionotropic receptor kainate type subunit 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr 5:143,052,442...143,268,873
Ensembl chr 5:137,767,865...137,984,307 		JBrowse link
G Grm8 glutamate metabotropic receptor 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr 4:56,771,247...57,696,951
Ensembl chr 4:55,805,955...56,730,831 		JBrowse link
G Grp gastrin releasing peptide disease_progression ISO protein:increased expression:serum (human) RGD PMID:30146822 RGD:401700396 NCBI chr18:61,658,655...61,672,037
Ensembl chr18:59,388,274...59,402,061 		JBrowse link
G Id2 inhibitor of DNA binding 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23582323 NCBI chr 6:47,469,162...47,470,995
Ensembl chr 6:41,728,946...41,744,400 		JBrowse link
G Insm1 INSM transcriptional repressor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23582323 NCBI chr 3:154,093,310...154,096,243
Ensembl chr 3:133,639,580...133,643,003 		JBrowse link
G Itgb1 integrin subunit beta 1 disease_progression
treatment		 ISO RGD PMID:21063403 PMID:12168902 RGD:13792831, RGD:13792832 NCBI chr19:73,602,277...73,650,271
Ensembl chr19:56,705,171...56,753,195 		JBrowse link
G Kdm6a lysine demethylase 6A ISO DNA:mutations:multiple: (human) RGD PMID:31199602 RGD:150429733 NCBI chr  X:6,920,374...7,060,027
Ensembl chr  X:4,337,750...4,477,062 		JBrowse link
G Khsrp KH-type splicing regulatory protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr 9:1,949,557...1,959,400
Ensembl chr 9:1,862,899...1,872,451 		JBrowse link
G Kif21a kinesin family member 21A ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr 7:123,942,079...124,058,594
Ensembl chr 7:122,062,537...122,178,999 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:15499612 NCBI chr14:32,901,615...32,978,895
Ensembl chr14:32,548,877...32,624,652 		JBrowse link
G Kmt2a lysine methyltransferase 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941188 NCBI chr 8:54,013,547...54,089,219
Ensembl chr 8:45,118,814...45,193,181 		JBrowse link
G Kmt2d lysine methyltransferase 2D disease_progression ISO DNA:missense mutations, insertion/deletion:plasma RGD PMID:28007623 PMID:29748005 PMID:27873319 PMID:29627316 RGD:150523766, RGD:127285383, RGD:150523768, RGD:150523767 NCBI chr 7:131,859,696...131,901,032
Ensembl chr 7:129,962,887...130,020,325 		JBrowse link
G Lama3 laminin subunit alpha 3 ISO DNA:hyper-methylation:promoter: RGD PMID:12855645 RGD:13793369 NCBI chr18:3,797,898...4,033,021
Ensembl chr18:3,523,133...3,751,353 		JBrowse link
G Lamb3 laminin subunit beta 3 ISO DNA:hyper-methylation:promoter: RGD PMID:12855645 RGD:13793369 NCBI chr13:107,362,514...107,404,081
Ensembl chr13:104,833,873...104,875,405 		JBrowse link
G Lamc2 laminin subunit gamma 2 ISO DNA:hyper-methylation:promoter: RGD PMID:12855645 RGD:13793369 NCBI chr13:67,835,199...67,894,694
Ensembl chr13:65,284,664...65,344,200 		JBrowse link
G Lyrm9 LYR motif containing 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr10:64,223,732...64,237,791
Ensembl chr10:63,725,743...63,739,772 		JBrowse link
G Max MYC associated factor X ISO DNA:loss of heterozygosity:lung RGD PMID:24362264 RGD:13793386 NCBI chr 6:101,369,989...101,395,333
Ensembl chr 6:95,636,858...95,662,137 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase severity ISO protein:missense mutation:cds:p.A222V (human) RGD PMID:17533396 RGD:4891158 NCBI chr 5:163,748,346...163,768,141
Ensembl chr 5:158,465,296...158,483,797 		JBrowse link
G Mtor mechanistic target of rapamycin kinase disease_progression ISO DNA:SNP: :rs2536(human) RGD PMID:28280736 RGD:13825123 NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor disease_progression ISO RGD PMID:28089889 RGD:13793389 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Mycl MYCL proto-oncogene, bHLH transcription factor ISO CTD Direct Evidence: therapeutic CTD PMID:22941189 NCBI chr 5:135,274,713...135,281,584
Ensembl chr 5:135,274,748...135,281,582 		JBrowse link
G Ndrg1 N-myc downstream regulated 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15341671 NCBI chr 7:100,573,526...100,614,902
Ensembl chr 7:98,684,487...98,725,880 		JBrowse link
G Notch1 notch receptor 1 treatment IEP RGD PMID:33628824 RGD:155663482 NCBI chr 3:29,676,040...29,721,613
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Pbrm1 polybromo 1 disease_progression ISO RGD PMID:29748005 RGD:127285383 NCBI chr16:6,219,933...6,319,336
Ensembl chr16:6,213,300...6,311,780 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha ISO ClinVar Annotator: match by term: Small cell lung carcinoma ClinVar PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 More... NCBI chr 2:117,103,643...117,177,411
Ensembl chr 2:115,174,984...115,249,032 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 disease_progression ISO DNA:SNPs: :rs3756668,rs12755(human) RGD PMID:28280736 RGD:13825123 NCBI chr 2:34,612,946...34,697,660
Ensembl chr 2:32,882,032...32,963,631 		JBrowse link
G Plscr4 phospholipid scramblase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr 8:101,867,057...101,905,827
Ensembl chr 8:92,987,381...93,026,049 		JBrowse link
G Pten phosphatase and tensin homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941188 NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Ptk2 protein tyrosine kinase 2 disease_progression ISO DNA:CNV:: RGD PMID:21800286 PMID:20802517 RGD:13825133, RGD:13825141 NCBI chr 7:107,015,730...107,220,865
Ensembl chr 7:105,126,728...105,331,783 		JBrowse link
G Rad52 RAD52 homolog, DNA repair protein susceptibility
treatment		 ISO DNA:SNP:3'utr: (rs7963551) (human)
DNA:SNP: (rs10774474)(human)		 RGD PMID:26629180 PMID:27531263 RGD:151660337, RGD:151660339 NCBI chr 4:154,778,320...154,802,002
Ensembl chr 4:153,106,062...153,128,207 		JBrowse link
G Rarb retinoic acid receptor, beta ISO DNA:methylation: : RGD PMID:29851970 RGD:13825142 NCBI chr15:10,837,252...11,482,037
Ensembl chr15:8,406,492...9,051,288 		JBrowse link
G Rassf8 Ras association domain family member 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr 4:178,716,110...178,798,042
Ensembl chr 4:178,719,992...178,796,690 		JBrowse link
G Rb1 RB transcriptional corepressor 1 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Small cell lung carcinoma		 CTD
ClinVar		 PMID:2594029 PMID:22941188 PMID:22941189 PMID:25741868 NCBI chr15:54,780,858...54,911,989
Ensembl chr15:48,371,296...48,502,302 		JBrowse link
G Rictor RPTOR independent companion of MTOR, complex 2 severity ISO associated with Neoplasm Metastasis; protein:increased expression:lung, lymph node (human)
DNA:CNV, amplification:exon (human)		 RGD PMID:31454632 PMID:27863413 RGD:152995447, RGD:152995517 NCBI chr 2:57,539,279...57,631,291
Ensembl chr 2:55,811,322...55,901,426 		JBrowse link
G Rims2 regulating synaptic membrane exocytosis 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr 7:72,133,004...72,644,059
Ensembl chr 7:70,243,872...70,757,491 		JBrowse link
G Runx1t1 RUNX1 partner transcriptional co-repressor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr 5:31,984,946...32,136,878
Ensembl chr 5:27,187,551...27,335,592 		JBrowse link
G Satb2 SATB homeobox 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr 9:65,842,351...66,028,569
Ensembl chr 9:58,350,246...58,530,707 		JBrowse link
G Skp2 S-phase kinase associated protein 2 ISO mRNA:increased expression:lung: RGD PMID:12107105 RGD:13825152 NCBI chr 2:59,888,406...59,916,471
Ensembl chr 2:58,161,229...58,189,338 		JBrowse link
G Slit2 slit guidance ligand 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941188 NCBI chr14:66,829,661...67,168,517
Ensembl chr14:62,617,067...62,955,948 		JBrowse link
G Smarca4 SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26343384 NCBI chr 8:28,438,370...28,535,071
Ensembl chr 8:20,167,717...20,258,975 		JBrowse link
G Sox2 SRY-box transcription factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr 2:119,465,131...119,467,542
Ensembl chr 2:117,536,929...117,539,338 		JBrowse link
G Tmem132d transmembrane protein 132D ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr12:33,905,971...34,553,267
Ensembl chr12:28,270,712...28,915,374 		JBrowse link
G Tp53 tumor protein p53 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941188 PMID:22941189 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tp73 tumor protein p73 ISO DNA:mutations:multiple: (human) RGD PMID:26168399 RGD:151347582 NCBI chr 5:169,903,801...169,988,075
Ensembl chr 5:164,621,377...164,681,128 		JBrowse link
G Ttr transthyretin ISO protein:increased expression:lung (human) RGD PMID:26943652 RGD:151665207 NCBI chr18:12,216,684...12,225,972
Ensembl chr18:11,943,789...11,951,008 		JBrowse link
G Ubxn11 UBX domain protein 11 ISO ClinVar Annotator: match by term: Small cell lung cancer | ClinVar Annotator: match by term: Small cell lung carcinoma ClinVar NCBI chr 5:151,613,411...151,637,274
Ensembl chr 5:146,329,842...146,353,526 		JBrowse link
G Xpo5 exportin 5 severity ISO DNA:snp, haplotype:3' utr:c.*659A>C (rs11077) (human) RGD PMID:24648983 RGD:11041738 NCBI chr 9:22,237,760...22,275,745
Ensembl chr 9:14,740,182...14,778,171 		JBrowse link
G Zdbf2 zinc finger, DBF-type containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr 9:72,203,598...72,242,287
Ensembl chr 9:64,709,880...64,744,265 		JBrowse link
lung squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alk ALK receptor tyrosine kinase ISO ClinVar Annotator: match by term: Squamous cell lung carcinoma ClinVar PMID:24033266 PMID:24728327 PMID:25741868 PMID:28492532 NCBI chr 6:28,631,431...29,351,321
Ensembl chr 6:22,880,625...23,598,034 		JBrowse link
G Arhgap44 Rho GTPase activating protein 44 ISO mRNA:decreased expression:lung (human) RGD PMID:28527113 RGD:401901290 NCBI chr10:50,154,724...50,322,027
Ensembl chr10:49,655,584...49,824,297 		JBrowse link
G Arid1a AT-rich interaction domain 1A exacerbates ISO protein:decreased expression:lung (human) RGD PMID:32823232 RGD:126848760 NCBI chr 5:151,192,014...151,269,291
Ensembl chr 5:145,908,181...145,985,564 		JBrowse link
G Arpc5 actin related protein 2/3 complex, subunit 5 ISO mRNA:increased expression:lung (human) RGD PMID:22089643 RGD:11049488 NCBI chr13:64,904,504...64,913,413
Ensembl chr13:64,887,136...64,913,410 		JBrowse link
G Atm ATM serine/threonine kinase susceptibility ISO DNA:SNP:intron:(rs228589) (human) RGD PMID:28642860 RGD:150383339 NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Atrx ATRX, chromatin remodeler severity ISO RGD PMID:31374064 RGD:127285382 NCBI chr  X:74,916,548...75,062,880
Ensembl chr  X:70,850,981...70,997,330 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 disease_progression ISO mRNA:increased expression:lung (human) RGD PMID:31964418 RGD:153344516 NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Birc6 baculoviral IAP repeat-containing 6 disease_progression ISO mRNA:increased expression:lung (human) RGD PMID:31964418 RGD:153344516 NCBI chr 6:26,474,843...26,668,275
Ensembl chr 6:20,722,922...20,916,434 		JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase ISO ClinVar Annotator: match by term: Squamous cell lung carcinoma ClinVar PMID:12068308 PMID:12460918 PMID:12460919 PMID:12960123 PMID:14612909 More... NCBI chr 4:69,329,772...69,476,931
Ensembl chr 4:68,384,649...68,510,463 		JBrowse link
G Bsg basigin ISO mRNA:increased expression:lung RGD PMID:9154157 RGD:2289059 NCBI chr 7:10,643,788...10,651,005
Ensembl chr 7:9,993,170...10,000,387 		JBrowse link
G Cblb Cbl proto-oncogene B disease_progression ISO RGD PMID:29384143 RGD:150540336 NCBI chr11:62,058,829...62,225,904
Ensembl chr11:48,592,703...48,756,839 		JBrowse link
G Ccnd1 cyclin D1 disease_progression ISO protein:increased expression:lung RGD PMID:27498289 RGD:13434929 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccnd2 cyclin D2 ISO DNA:hypermethylation:promoter RGD PMID:30308939 RGD:151665105 NCBI chr 4:161,653,048...161,675,422
Ensembl chr 4:159,962,363...159,989,495 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 ISO protein:increased expression:lung RGD PMID:9751261 RGD:13464277 NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:62,883,105...62,942,403 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A ISO ClinVar Annotator: match by term: Squamous cell lung carcinoma ClinVar PMID:8552400 PMID:8573142 PMID:9053859 PMID:9660926 PMID:10498896 More... NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Chd4 chromodomain helicase DNA binding protein 4 ISO mRNA:increased expression:lung (human) RGD PMID:28486105 RGD:153323299 NCBI chr 4:159,584,623...159,617,867
Ensembl chr 4:157,899,391...157,931,541 		JBrowse link
G Chrna5 cholinergic receptor nicotinic alpha 5 subunit susceptibility ISO DNA:SNP: :rs503464(human)
mRNA:increased expression:lung		 RGD PMID:23314339 PMID:20124469 RGD:150527849, RGD:150527851 NCBI chr 8:64,265,879...64,294,233
Ensembl chr 8:55,369,794...55,398,146 		JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit susceptibility ISO mRNA:increased expression:lung
DNA:hypomethylation:promoter:
DNA:SNP:: (rs7178270) (human)		 RGD PMID:20124469 PMID:22945651 PMID:23397474 RGD:150527851, RGD:151361154, RGD:151361148 NCBI chr 8:64,312,644...64,333,319
Ensembl chr 8:55,418,313...55,437,027 		JBrowse link
G Clptm1l CLPTM1-like susceptibility
no_association		 ISO mRNA:increased expression:lung
DNA:SNP: :rs401681(human)
DNA:SNP::rs401681(human)
DNA:SNP:: rs31490(human)		 RGD PMID:24366883 PMID:24386361 PMID:24861918 PMID:23908149 RGD:150530483, RGD:150537098, RGD:150530499, RGD:150530498 NCBI chr 1:31,496,094...31,512,148
Ensembl chr 1:29,667,545...29,683,530 		JBrowse link
G Crebbp CREB binding protein ISO ClinVar Annotator: match by term: Squamous cell carcinoma of lung ClinVar PMID:21390126 PMID:21680795 PMID:21796119 PMID:22832583 PMID:23334668 More... NCBI chr10:11,842,307...11,968,266
Ensembl chr10:11,335,953...11,461,888 		JBrowse link
G Csf1r colony stimulating factor 1 receptor ISO protein:increased expression:lung (human) RGD PMID:23702648 RGD:150524280 NCBI chr18:56,834,152...56,860,804
Ensembl chr18:54,546,659...54,590,415 		JBrowse link
G Ctnnb1 catenin beta 1 disease_progression ISO protein:increased expression:lung RGD PMID:27498289 RGD:13434929 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Cycs cytochrome c, somatic treatment ISO RGD PMID:25578497 RGD:13792769 NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 susceptibility ISO Carcinoma, Squamous Cell;DNA:snp:cds:p.A119S (human) RGD PMID:10739169 RGD:7829734 NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 severity ISO ClinVar Annotator: match by term: Squamous cell lung carcinoma
mRNA:increased expression:lung		 ClinVar
RGD		 PMID:22328973 PMID:25741868 PMID:26206333 PMID:28492532 PMID:24885564 More... RGD:150429702, RGD:150429703 NCBI chr13:84,726,412...84,851,032
Ensembl chr13:82,195,463...82,317,363 		JBrowse link
G E2f1 E2F transcription factor 1 treatment ISO RGD PMID:28927142 RGD:13464332 NCBI chr 3:163,524,739...163,535,563
Ensembl chr 3:143,049,478...143,075,361 		JBrowse link
G E2f3 E2F transcription factor 3 ISO RGD PMID:16938365 RGD:13464341 NCBI chr17:34,810,355...34,887,725
Ensembl chr17:34,601,830...34,676,253 		JBrowse link
G Eef2 eukaryotic translation elongation factor 2 disease_progression ISO protein:increased expression:lung (human) RGD PMID:27542262 RGD:153298910 NCBI chr 7:9,183,836...9,196,255
Ensembl chr 7:8,533,116...8,559,183 		JBrowse link
G Egfr epidermal growth factor receptor ISO ClinVar Annotator: match by term: Squamous cell lung carcinoma ClinVar PMID:20942962 PMID:24033266 PMID:25382819 PMID:25741868 PMID:27294619 More... NCBI chr14:95,378,626...95,551,358
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Emx2 empty spiracles homeobox 2 exacerbates ISO protein:decreased expression:lung (human) RGD PMID:26132438 RGD:11079903 NCBI chr 1:258,626,584...258,633,594
Ensembl chr 1:258,626,584...258,633,594 		JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor ISO mRNA, protein:increased expression:lung (human) RGD PMID:31615563 RGD:155260344 NCBI chr16:7,771,311...7,841,895
Ensembl chr16:7,765,013...7,835,587 		JBrowse link
G Ercc6l ERCC excision repair 6 like, spindle assembly checkpoint helicase ISO mRNA:increased expression:lung (human) RGD PMID:35150321 RGD:155260359 NCBI chr  X:71,285,380...71,301,186
Ensembl chr  X:67,245,414...67,280,756 		JBrowse link
G Fap fibroblast activation protein, alpha disease_progression ISO RGD PMID:26252379 RGD:152600901 NCBI chr 3:67,547,398...67,616,271
Ensembl chr 3:47,138,813...47,225,545 		JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 ISO ClinVar Annotator: match by term: Squamous cell carcinoma of lung | ClinVar Annotator: match by term: Squamous cell lung carcinoma ClinVar PMID:25741868 PMID:26619011 NCBI chr 2:172,447,738...172,609,591
Ensembl chr 2:170,149,694...170,309,941 		JBrowse link
G Fgf9 fibroblast growth factor 9 ISO mRNA:decreased expression:lung (human) RGD PMID:28440022 RGD:152180844 NCBI chr15:36,325,552...36,369,995
Ensembl chr15:32,210,074...32,253,309 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 ISO ClinVar Annotator: match by term: Squamous cell lung carcinoma ClinVar NCBI chr 1:194,175,703...194,280,914
Ensembl chr 1:184,745,420...184,850,626 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 ISO ClinVar Annotator: match by term: Squamous cell carcinoma of lung | ClinVar Annotator: match by term: Squamous cell lung carcinoma ClinVar PMID:8589699 PMID:10471491 PMID:11038465 PMID:11879084 PMID:15772091 More... NCBI chr14:81,211,800...81,227,215
Ensembl chr14:76,987,993...77,003,341 		JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 disease_progression ISO human cells in mouse model RGD PMID:29402970 RGD:150429984 NCBI chr17:9,466,686...9,481,423
Ensembl chr17:9,461,547...9,476,242 		JBrowse link
G Frzb frizzled-related protein ISO protein:decreased expression:lung (human) RGD PMID:27623992 RGD:32716395 NCBI chr 3:85,739,162...85,772,168
Ensembl chr 3:65,332,277...65,365,208 		JBrowse link
G Fubp1 far upstream element binding protein 1 ISO mRNA:decreased expression:lung (human) RGD PMID:32481602 RGD:151361197 NCBI chr 2:243,819,529...243,846,544
Ensembl chr 2:241,159,512...241,186,602 		JBrowse link
G Gpx1 glutathione peroxidase 1 susceptibility ISO DNA:missense mutation:CDS:p.P198L (rs1050450) (human)
DNA:missense mutation:CDS:p.P200L (rs1050450) (human)		 RGD PMID:16797832 PMID:18298806 RGD:152995481, RGD:152995507 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Hras HRas proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Squamous cell lung carcinoma ClinVar PMID:16372351 PMID:24033266 PMID:25741868 PMID:28492532 NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:196,296,263...196,300,615 		JBrowse link
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 ISO protein:increased expression:blood plasma (human) RGD PMID:24046070 RGD:149735540 NCBI chr 9:74,027,887...74,057,442
Ensembl chr 9:66,534,146...66,563,708 		JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 severity
susceptibility		 ISO protein:increased expression:lung (human)
protein:increased expression:blood serum (human)
DNA:SNP:CD: (rs11540478) C>T (human)		 RGD PMID:30128035 PMID:29465809 PMID:27649069 RGD:149735564, RGD:149735567, RGD:149735566 NCBI chr 1:143,447,925...143,467,248
Ensembl chr 1:134,029,772...134,058,025 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase ISO ClinVar Annotator: match by term: Squamous cell lung carcinoma ClinVar PMID:25741868 NCBI chr14:32,901,615...32,978,895
Ensembl chr14:32,548,877...32,624,652 		JBrowse link
G Kmt2d lysine methyltransferase 2D disease_progression ISO RGD PMID:24323028 PMID:30885352 PMID:28177435 RGD:150523770, RGD:150523777, RGD:150523776 NCBI chr 7:131,859,696...131,901,032
Ensembl chr 7:129,962,887...130,020,325 		JBrowse link
G Kras KRAS proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Squamous cell lung carcinoma ClinVar PMID:6695174 PMID:15696205 PMID:17704260 PMID:26242988 PMID:28492532 NCBI chr 4:179,916,255...179,949,613 JBrowse link
G Lamc2 laminin subunit gamma 2 disease_progression ISO RGD PMID:23124251 RGD:13793371 NCBI chr13:67,835,199...67,894,694
Ensembl chr13:65,284,664...65,344,200 		JBrowse link
G Lrrc56 leucine rich repeat containing 56 ISO ClinVar Annotator: match by term: Squamous cell lung carcinoma ClinVar PMID:16372351 PMID:24033266 PMID:25741868 PMID:28492532 NCBI chr 1:205,729,402...205,744,754
Ensembl chr 1:196,299,846...196,315,172 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 ISO ClinVar Annotator: match by term: Squamous cell lung carcinoma ClinVar PMID:25741868 NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:64,683,449...64,755,147 		JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 ISO mRNA:decreased expression:lung (human) RGD PMID:31089135 RGD:155253742 NCBI chr12:7,389,032...7,398,377
Ensembl chr12:2,591,219...2,604,222 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase ISO ClinVar Annotator: match by term: Squamous cell lung carcinoma ClinVar NCBI chr 4:46,756,823...46,864,041
Ensembl chr 4:45,790,791...45,897,876 		JBrowse link
G Mir154 microRNA 154 ISO associated with nicotine dependence; RNA:decreased expression:blood serum (human) RGD PMID:25386559 RGD:152995475 NCBI chr 6:134,574,352...134,574,435
Ensembl chr 6:128,752,947...128,753,030 		JBrowse link
G Mir193a microRNA 193a exacerbates ISO DNA:Hypermethylation RGD PMID:22282464 RGD:153344598 NCBI chr10:65,170,306...65,170,417
Ensembl chr10:64,672,343...64,672,454 		JBrowse link
G Mir20a microRNA 20a ISO RGD PMID:26560875 RGD:11572141 NCBI chr15:98,588,303...98,588,387
Ensembl chr15:92,181,084...92,181,168 		JBrowse link
G Mir210 microRNA 210 ISO miRNA:increased expression:sputum (human) RGD PMID:27777637 RGD:152998954 NCBI chr 1:205,755,923...205,756,032
Ensembl chr 1:196,326,337...196,326,454 		JBrowse link
G Mir31 microRNA 31 severity ISO RNA:increased expression:blood serum (human)
RNA:increased expression:lung (human)		 RGD PMID:21658006 PMID:21890451 RGD:152998938, RGD:152998950 NCBI chr 5:108,714,849...108,714,954 JBrowse link
G Mir497 microRNA 497 ISO RGD PMID:31115562 RGD:126925181 NCBI chr10:55,450,171...55,450,239
Ensembl chr10:54,951,505...54,951,584 		JBrowse link
G Mir9-3 microRNA 9-3 exacerbates ISO DNA:Hypermethylation RGD PMID:22282464 RGD:153344598 NCBI chr 1:142,849,400...142,849,489 JBrowse link
G Pdgfra platelet derived growth factor receptor alpha ISO ClinVar Annotator: match by term: Squamous cell lung carcinoma ClinVar PMID:24033266 PMID:25741868 PMID:28492532 NCBI chr14:33,360,027...33,408,604
Ensembl chr14:33,005,839...33,054,335 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha ISO ClinVar Annotator: match by term: Squamous cell lung carcinoma ClinVar PMID:25741868 NCBI chr 2:117,103,643...117,177,411
Ensembl chr 2:115,174,984...115,249,032 		JBrowse link
G Pole DNA polymerase epsilon, catalytic subunit ameliorates ISO DNA:mutations:multiple (human) RGD PMID:29650000 RGD:151347653 NCBI chr12:52,005,155...52,053,761
Ensembl chr12:46,345,420...46,393,939 		JBrowse link
G Prex2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 ISO mRNA:increased expression:lung (human) RGD PMID:32537022 RGD:151665184 NCBI chr 5:12,720,683...13,036,077
Ensembl chr 5:7,942,573...8,253,068 		JBrowse link
G Ptch1 patched 1 disease_progression ISO DNA:CNVs RGD PMID:21889114 RGD:150524337 NCBI chr17:1,548,449...1,613,461
Ensembl chr17:1,542,877...1,607,333 		JBrowse link
G Pten phosphatase and tensin homolog ISO ClinVar Annotator: match by term: Squamous cell lung carcinoma ClinVar NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Ptk2 protein tyrosine kinase 2 severity ISO RGD PMID:23906871 RGD:152176664 NCBI chr 7:107,015,730...107,220,865
Ensembl chr 7:105,126,728...105,331,783 		JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 ISO ClinVar Annotator: match by term: Squamous cell carcinoma of lung ClinVar PMID:11704759 PMID:12634870 PMID:12717436 PMID:14644997 PMID:14974085 More... NCBI chr12:41,026,079...41,085,577
Ensembl chr12:35,383,144...35,424,925 		JBrowse link
G Ptpn13 protein tyrosine phosphatase, non-receptor type 13 susceptibility
severity		 ISO mRNA,protein:decreased expression:lung
DNA:missense mutations:cds:p.I1522M, p.Y2081D (human)		 RGD PMID:22245727 PMID:19672627 PMID:23906871 RGD:152176663, RGD:152176665, RGD:152176664 NCBI chr14:6,412,841...6,587,238
Ensembl chr14:6,108,211...6,282,563 		JBrowse link
G Ptprj protein tyrosine phosphatase, receptor type, J susceptibility ISO DNA:missense mutations:cds:p.R326Q, p.Q276P (human) RGD PMID:19672627 RGD:152176665 NCBI chr 3:96,861,785...97,017,702
Ensembl chr 3:76,405,927...76,562,260 		JBrowse link
G Rad52 RAD52 homolog, DNA repair protein ameliorates
susceptibility		 ISO DNA:SNP: (rs6489769) (human) RGD PMID:28415565 PMID:22585858 RGD:151660334, RGD:151660345 NCBI chr 4:154,778,320...154,802,002
Ensembl chr 4:153,106,062...153,128,207 		JBrowse link
G Sftpb surfactant protein B susceptibility ISO DNA:polymorphism:intron (human)
DNA:variants:intron:		 RGD PMID:16570259 PMID:12107845 RGD:4143389, RGD:151667424 NCBI chr 4:105,917,495...105,926,631
Ensembl chr 4:104,359,396...104,368,436 		JBrowse link
G Slc7a5 solute carrier family 7 member 5 ISO RGD PMID:19068093 RGD:151361158 NCBI chr19:66,843,808...66,872,412
Ensembl chr19:49,935,220...49,963,823 		JBrowse link
G Sox30 SRY-box transcription factor 30 disease_progression ISO RGD PMID:26330328 RGD:11535423 NCBI chr10:30,918,707...30,948,415
Ensembl chr10:30,418,473...30,446,453 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase severity ISO RGD PMID:12826049 RGD:150521546 NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Srsf1 serine and arginine rich splicing factor 1 ISO protein:increased expression:lung epithelium RGD PMID:23071587 RGD:150429662 NCBI chr10:73,335,519...73,342,549
Ensembl chr10:72,839,274...72,845,336 		JBrowse link
G Srsf2 serine and arginine rich splicing factor 2 ISO protein:increased expression:lung epithelium,nucleus RGD PMID:23071587 RGD:150429662 NCBI chr10:102,550,962...102,554,200
Ensembl chr10:102,052,314...102,055,338 		JBrowse link
G Stk11 serine/threonine kinase 11 ISO ClinVar Annotator: match by term: Squamous cell lung carcinoma ClinVar PMID:15800014 PMID:17676035 PMID:25741868 PMID:28492532 NCBI chr 7:10,225,204...10,241,965
Ensembl chr 7:9,575,269...9,591,315 		JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 ISO DNA:SNP:exon:p.R213H, 638G>A (human) RGD PMID:14688021 RGD:1581441 NCBI chr 1:190,702,592...190,706,112
Ensembl chr 1:181,272,023...181,275,562 		JBrowse link
G Tert telomerase reverse transcriptase susceptibility ISO DNA:SNP:: rs2853669(human)
DNA:SNP::rs33963617(human)		 RGD PMID:23908149 PMID:31935503 RGD:150530498, RGD:150530635 NCBI chr 1:31,465,766...31,488,650
Ensembl chr 1:29,637,506...29,659,561 		JBrowse link
G Tp53 tumor protein p53 ISO ClinVar Annotator: match by term: Squamous cell lung carcinoma ClinVar PMID:1349175 PMID:1359493 PMID:1565143 PMID:1565144 PMID:1591732 More... NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tp73 tumor protein p73 treatment ISO DNA:SNP:: rs2273953(human)
mRNA:increased expression:lung (human)		 RGD PMID:30420492 PMID:27246533 RGD:151347580, RGD:151347584 NCBI chr 5:169,903,801...169,988,075
Ensembl chr 5:164,621,377...164,681,128 		JBrowse link
malignant mesothelioma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1b activin A receptor type 1B ameliorates ISO RGD PMID:30061637 RGD:151665492 NCBI chr 7:134,164,987...134,208,389
Ensembl chr 7:132,286,275...132,329,673 		JBrowse link
G Ada adenosine deaminase treatment ISO RGD PMID:17952507 RGD:152995277 NCBI chr 3:172,818,174...172,842,283
Ensembl chr 3:152,398,747...152,447,088 		JBrowse link
G Adamts2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26139392 NCBI chr10:35,422,030...35,627,483
Ensembl chr10:34,921,049...35,123,821 		JBrowse link
G Ago1 argonaute RISC component 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 5:144,006,618...144,064,740
Ensembl chr 5:138,722,111...138,773,546 		JBrowse link
G Ago2 argonaute RISC catalytic component 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 7:106,907,209...106,994,124
Ensembl chr 7:105,029,120...105,104,974 		JBrowse link
G Anxa2 annexin A2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20682992 NCBI chr 8:78,986,252...79,022,638
Ensembl chr 8:70,105,253...70,141,658 		JBrowse link
G Apoa1 apolipoprotein A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23056237 NCBI chr 8:55,423,945...55,425,729
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G Bap1 BRCA1 associated deubiquitinase 1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:24928783 PMID:25231345 PMID:26463840 PMID:26928227 PMID:29112861 More... RGD:9586039 NCBI chr16:6,453,126...6,461,952
Ensembl chr16:6,446,709...6,455,535 		JBrowse link
G Bcl10 BCL10, immune signaling adaptor ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Mesothelioma, malignant | ClinVar Annotator: match by term: Mesothelioma, somatic		 OMIM
CTD
ClinVar		 PMID:9989495 PMID:10380920 PMID:10408400 PMID:25741868 PMID:28492532 NCBI chr 2:237,501,181...237,510,821
Ensembl chr 2:234,840,858...234,850,523 		JBrowse link
G Bcl2 BCL2, apoptosis regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:16850164 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G C9 complement C9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23056237 NCBI chr 2:57,300,510...57,348,759
Ensembl chr 2:55,572,992...55,621,338 		JBrowse link
G Calb2 calbindin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22784439 NCBI chr19:38,114,435...38,141,438
Ensembl chr19:38,114,424...38,141,438 		JBrowse link
G Ccl27 C-C motif chemokine ligand 27 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr 5:61,737,261...61,744,375
Ensembl chr 5:56,941,402...56,948,506 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Ccl7 C-C motif chemokine ligand 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr10:67,514,095...67,515,945
Ensembl chr10:67,016,446...67,018,303 		JBrowse link
G Ccne2 cyclin E2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 5:29,082,169...29,094,879
Ensembl chr 5:24,284,922...24,297,632 		JBrowse link
G Cd40 CD40 molecule treatment ISO RGD PMID:22002241 RGD:11522742 NCBI chr 3:174,209,113...174,224,592
Ensembl chr 3:153,790,449...153,805,534 		JBrowse link
G Cdh5 cadherin 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28377727 NCBI chr19:821,875...860,931
Ensembl chr19:815,411...854,368 		JBrowse link
G Cdk6 cyclin-dependent kinase 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 4:31,592,384...31,784,732
Ensembl chr 4:30,646,460...30,829,634 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:11453316 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:19223589 PMID:21526190 PMID:29112861 PMID:37441092 NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Cfap45 cilia and flagella associated protein 45 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26928227 NCBI chr13:87,521,831...87,545,236
Ensembl chr13:84,981,728...85,012,878 		JBrowse link
G Cldn10 claudin 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28377727 NCBI chr15:102,269,858...102,361,589
Ensembl chr15:95,862,760...95,954,526 		JBrowse link
G Cldn15 claudin 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28377727 NCBI chr12:19,698,167...19,708,419
Ensembl chr12:19,698,337...19,706,819 		JBrowse link
G Cldn4 claudin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28377727 NCBI chr12:27,388,160...27,389,958
Ensembl chr12:21,751,331...21,753,436 		JBrowse link
G Cldn5 claudin 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28377727 NCBI chr11:95,717,172...95,718,598
Ensembl chr11:82,211,475...82,214,992 		JBrowse link
G Cldn8 claudin 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28377727 NCBI chr11:27,875,857...27,878,106
Ensembl chr11:27,875,692...27,878,513 		JBrowse link
G Clec11a C-type lectin domain containing 11A ISO CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr 1:94,800,456...94,809,002
Ensembl chr 1:94,801,496...94,804,633 		JBrowse link
G Col12a1 collagen type XII alpha 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 8:89,427,834...89,545,886
Ensembl chr 8:80,547,593...80,665,686 		JBrowse link
G Copg1 COPI coat complex subunit gamma 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26463840 NCBI chr 4:120,366,540...120,392,502
Ensembl chr 4:120,366,542...120,415,616 		JBrowse link
G Csf1 colony stimulating factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr 2:198,065,400...198,084,774
Ensembl chr 2:195,377,215...195,411,704 		JBrowse link
G Ctnnb1 catenin beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22784439 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Cxcl13 C-X-C motif chemokine ligand 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23056237 NCBI chr14:13,912,858...13,917,920
Ensembl chr14:13,608,902...13,613,933 		JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr14:16,007,166...16,012,077
Ensembl chr14:15,722,908...15,728,435 		JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked ISO CTD Direct Evidence: marker/mechanism CTD PMID:26928227 NCBI chr  X:12,152,346...12,165,983
Ensembl chr  X:9,479,532...9,493,168 		JBrowse link
G Ddx51 DEAD-box helicase 51 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26928227 NCBI chr12:46,011,303...46,015,989
Ensembl chr12:46,011,070...46,016,200 		JBrowse link
G Efemp1 EGF containing fibulin extracellular matrix protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27032653 NCBI chr14:106,811,769...106,890,961
Ensembl chr14:102,610,908...102,690,018 		JBrowse link
G Egfr epidermal growth factor receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:27032653 NCBI chr14:95,378,626...95,551,358
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Enox2 ecto-NOX disulfide-thiol exchanger 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26807072 NCBI chr  X:133,148,813...133,470,914
Ensembl chr  X:128,271,074...128,593,039 		JBrowse link
G Ephx1 epoxide hydrolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16697254 NCBI chr13:95,246,079...95,275,852
Ensembl chr13:92,714,315...92,790,235 		JBrowse link
G F9 coagulation factor IX ISO CTD Direct Evidence: marker/mechanism CTD PMID:23056237 NCBI chr  X:143,388,642...143,433,143
Ensembl chr  X:138,352,298...138,396,835 		JBrowse link
G Fgd6 FYVE, RhoGEF and PH domain containing 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 7:28,597,609...28,712,908
Ensembl chr 7:28,597,609...28,712,456 		JBrowse link
G Fgf18 fibroblast growth factor 18 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr10:18,210,240...18,241,929
Ensembl chr10:17,706,174...17,736,818 		JBrowse link
G Fgf9 fibroblast growth factor 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr15:36,325,552...36,369,995
Ensembl chr15:32,210,074...32,253,309 		JBrowse link
G Fn1 fibronectin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23056237 NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Fth1 ferritin heavy chain 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26818092 NCBI chr 1:216,052,037...216,054,325
Ensembl chr 1:206,627,103...206,725,424 		JBrowse link
G Gpr27 G protein-coupled receptor 27 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 4:132,328,364...132,329,497
Ensembl chr 4:132,328,364...132,329,497 		JBrowse link
G Gpr37 G protein-coupled receptor 37 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 4:55,104,355...55,126,420
Ensembl chr 4:54,138,870...54,161,001 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 ISO DNA:deletion:cds (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:16697254 PMID:7606714 RGD:7495814 NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Hdac4 histone deacetylase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 9:99,950,972...100,200,994
Ensembl chr 9:92,507,611...92,750,164 		JBrowse link
G Heph hephaestin ISO CTD Direct Evidence: marker/mechanism CTD PMID:26818092 NCBI chr  X:65,160,628...65,412,457
Ensembl chr  X:61,296,345...61,402,980 		JBrowse link
G Hgf hepatocyte growth factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr 4:19,628,902...19,700,467
Ensembl chr 4:18,677,101...18,745,409 		JBrowse link
G Htra1 HtrA serine peptidase 1 disease_progression ISO protein:increased expression:mesothelium (human) RGD PMID:18681782 RGD:152975625 NCBI chr 1:194,928,069...194,977,619
Ensembl chr 1:185,497,735...185,547,379 		JBrowse link
G Icam2 intercellular adhesion molecule 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23056237 NCBI chr10:91,308,608...91,319,536
Ensembl chr10:91,308,538...91,315,293 		JBrowse link
G Ifng interferon gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Igf2bp3 insulin-like growth factor 2 mRNA binding protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23621518 NCBI chr 4:79,391,367...79,525,923
Ensembl chr 4:78,060,494...78,194,865 		JBrowse link
G Il12b interleukin 12B ISO CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr10:29,390,300...29,405,194
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G Il1a interleukin 1 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il2ra interleukin 2 receptor subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr17:71,759,802...71,808,475
Ensembl chr17:66,849,974...66,898,697 		JBrowse link
G Il3 interleukin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr10:38,906,460...38,908,810
Ensembl chr10:38,405,716...38,408,066 		JBrowse link
G Il4 interleukin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Ilk integrin-linked kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23045294 NCBI chr 1:169,500,716...169,506,972
Ensembl chr 1:160,088,897...160,095,140 		JBrowse link
G Kat5 lysine acetyltransferase 5 ISO CTD Direct Evidence: therapeutic CTD PMID:26780987 NCBI chr 1:212,325,089...212,332,640
Ensembl chr 1:202,895,751...202,903,458 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23056237 NCBI chr14:32,901,615...32,978,895
Ensembl chr14:32,548,877...32,624,652 		JBrowse link
G Limch1 LIM and calponin homology domains 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr14:41,466,433...41,779,477
Ensembl chr14:41,114,803...41,425,191 		JBrowse link
G Lta lymphotoxin alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr20:3,622,291...3,625,852
Ensembl chr20:3,618,853...3,620,859 		JBrowse link
G Mcam melanoma cell adhesion molecule disease_progression IEP
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:22784439 PMID:23621518 PMID:23621518 RGD:7364782 NCBI chr 8:53,376,225...53,384,407
Ensembl chr 8:44,479,376...44,487,571 		JBrowse link
G Mdk midkine ISO CTD Direct Evidence: marker/mechanism CTD PMID:23056237 NCBI chr 3:98,356,789...98,358,960
Ensembl chr 3:77,901,158...77,903,130 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 4:46,756,823...46,864,041
Ensembl chr 4:45,790,791...45,897,876 		JBrowse link
G Mif macrophage migration inhibitory factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr20:12,767,138...12,791,222
Ensembl chr20:12,790,902...12,799,504
Ensembl chr 4:12,790,902...12,799,504 		JBrowse link
G Mir125a microRNA 125a ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 1:67,350,675...67,350,759
Ensembl chr 1:58,677,626...58,677,710 		JBrowse link
G Mir126a microRNA 126a ISO CTD Direct Evidence: marker/mechanism CTD PMID:21483773 NCBI chr 3:29,813,150...29,813,267
Ensembl chr 3:9,415,063...9,415,180 		JBrowse link
G Mir32 microRNA 32 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27716620 NCBI chr 5:71,596,083...71,596,152
Ensembl chr 5:71,596,083...71,596,152 		JBrowse link
G Mir484 microRNA 484 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr10:1,394,905...1,394,981
Ensembl chr10:887,684...887,760 		JBrowse link
G Mlana melan-A ISO CTD Direct Evidence: marker/mechanism CTD PMID:22784439 NCBI chr 1:227,469,537...227,483,343
Ensembl chr 1:227,469,537...227,483,343 		JBrowse link
G Msln mesothelin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19190155 PMID:27032653 NCBI chr10:15,276,489...15,285,921
Ensembl chr10:14,771,961...14,777,643 		JBrowse link
G Mtmr4 myotubularin related protein 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr10:72,890,665...72,913,598
Ensembl chr10:72,392,551...72,416,342 		JBrowse link
G Muc1 mucin 1, cell surface associated ISO CTD Direct Evidence: marker/mechanism CTD PMID:22784439 NCBI chr 2:176,933,312...176,938,497
Ensembl chr 2:174,635,995...174,640,733 		JBrowse link
G Nanos1 nanos C2HC-type zinc finger 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 1:259,897,663...259,901,561
Ensembl chr 1:259,897,939...259,898,730 		JBrowse link
G Nat2 N-acetyltransferase 2 susceptibility ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:16697254 PMID:15993904 RGD:5131858 NCBI chr16:26,974,874...27,005,191
Ensembl chr16:22,208,194...22,238,520 		JBrowse link
G Nf2 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor disease_progression ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:23435014 PMID:26463840 PMID:26678224 PMID:26928227 PMID:29112861 More... RGD:150530636, RGD:150530640 NCBI chr14:83,850,894...83,934,263
Ensembl chr14:79,627,399...79,710,667 		JBrowse link
G Ngf nerve growth factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:25162674 NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Osmr oncostatin M receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 2:57,634,517...57,688,802
Ensembl chr 2:55,907,132...55,961,262 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21543585 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pdpn podoplanin ISO CTD Direct Evidence: marker/mechanism CTD PMID:22784439 NCBI chr 5:160,884,995...160,919,112
Ensembl chr 5:155,601,691...155,635,656 		JBrowse link
G Pllp plasmolipin ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr19:10,315,104...10,335,892
Ensembl chr19:10,315,104...10,335,892 		JBrowse link
G Ptprf protein tyrosine phosphatase, receptor type, F ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 5:137,027,376...137,109,405
Ensembl chr 5:131,742,754...131,810,023 		JBrowse link
G Pycard PYD and CARD domain containing ISO CTD Direct Evidence: marker/mechanism CTD PMID:26935421 NCBI chr 1:192,032,124...192,033,419
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 4:150,352,158...150,412,813
Ensembl chr 4:148,679,530...148,740,317 		JBrowse link
G Rxra retinoid X receptor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 3:31,387,892...31,474,415
Ensembl chr 3:10,989,832...11,073,712 		JBrowse link
G Ryr2 ryanodine receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26928227 NCBI chr17:63,081,527...63,667,141
Ensembl chr17:58,389,925...58,975,142 		JBrowse link
G S100b S100 calcium binding protein B ISO CTD Direct Evidence: marker/mechanism CTD PMID:28377727 NCBI chr20:12,372,345...12,381,159
Ensembl chr20:12,372,881...12,394,743 		JBrowse link
G Sdc1 syndecan 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27032653 NCBI chr 6:37,282,041...37,304,503
Ensembl chr 6:31,562,739...31,585,264 		JBrowse link
G Sema4f semaphorin 4F ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 4:116,969,137...116,995,442
Ensembl chr 4:115,411,417...115,437,721 		JBrowse link
G Serpina4 serpin family A member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23056237 NCBI chr 6:128,764,738...128,773,858
Ensembl chr 6:122,999,900...123,009,082 		JBrowse link
G Setd2 SET domain containing 2, histone lysine methyltransferase ISO CTD Direct Evidence: marker/mechanism
DNA:mutations:multiple (human)		 CTD
RGD		 PMID:26928227 PMID:27834213 RGD:150429641 NCBI chr 8:119,390,207...119,475,863
Ensembl chr 8:110,511,772...110,597,489 		JBrowse link
G Setdb1 SET domain bifurcated histone lysine methyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26928227 NCBI chr 2:185,587,722...185,619,084
Ensembl chr 2:182,898,738...182,930,506 		JBrowse link
G Sf3b1 splicing factor 3b, subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26928227 NCBI chr 9:63,986,829...64,026,723
Ensembl chr 9:56,492,403...56,532,300 		JBrowse link
G Shbg sex hormone binding globulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:28377727 NCBI chr10:54,831,716...54,849,162
Ensembl chr10:54,332,941...54,351,057 		JBrowse link
G Slc22a5 solute carrier family 22 member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr10:38,509,072...38,536,240
Ensembl chr10:38,008,311...38,035,309 		JBrowse link
G Slc2a1 solute carrier family 2 member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22784439 NCBI chr 5:138,002,522...138,030,742
Ensembl chr 5:132,717,196...132,745,416 		JBrowse link
G Smarca2 SWI/SNF related BAF chromatin remodeling complex subunit ATPase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 1:233,617,277...233,784,908
Ensembl chr 1:224,191,125...224,358,684 		JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20617513 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Tbl1xr1 TBL1X/Y related 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 2:106,718,811...106,857,989
Ensembl chr 2:104,801,721...104,929,055 		JBrowse link
G Tf transferrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:26818092 NCBI chr 8:112,668,667...112,695,376
Ensembl chr 8:103,767,995...103,816,511 		JBrowse link
G Tfdp2 transcription factor Dp-2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr 8:105,640,018...105,781,026
Ensembl chr 8:96,760,504...96,896,682 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr13:100,691,540...100,793,227
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
G Tnfrsf8 TNF receptor superfamily member 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23056237 NCBI chr 5:162,406,387...162,451,620
Ensembl chr 5:157,123,185...157,168,421 		JBrowse link
G Tp53 tumor protein p53 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26928227 PMID:37441092 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Traf7 TNF receptor associated factor 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26928227 NCBI chr10:14,038,117...14,056,832
Ensembl chr10:13,533,570...13,552,203 		JBrowse link
G Txn1 thioredoxin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27032653 NCBI chr 5:77,507,455...77,519,685
Ensembl chr 5:72,711,933...72,724,629 		JBrowse link
G Ulk2 unc-51 like autophagy activating kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26928227 NCBI chr10:46,951,038...47,029,844
Ensembl chr10:46,454,030...46,530,407 		JBrowse link
G Vim vimentin ISO CTD Direct Evidence: marker/mechanism CTD PMID:22784439 NCBI chr17:81,577,261...81,585,746
Ensembl chr17:76,668,647...76,677,187 		JBrowse link
G Wnt3 Wnt family member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr10:89,180,224...89,224,195
Ensembl chr10:88,680,248...88,724,099 		JBrowse link
G Wt1 WT1 transcription factor ISO ClinVar Annotator: match by term: Mesothelioma, malignant
CTD Direct Evidence: marker/mechanism		 OMIM
ClinVar
CTD		 PMID:1302008 PMID:1327525 PMID:1338906 PMID:1655284 PMID:1658787 More... NCBI chr 3:112,019,721...112,068,454
Ensembl chr 3:91,567,001...91,613,643 		JBrowse link
G Wwc1 WW and C2 domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25756049 NCBI chr10:20,804,173...20,958,437
Ensembl chr10:20,300,833...20,454,497 		JBrowse link
G Xrcc1 X-ray repair cross complementing 1 treatment ISO RGD PMID:22982660 RGD:151347428 NCBI chr 1:89,268,721...89,296,619
Ensembl chr 1:80,141,207...80,168,701 		JBrowse link
Malignant Pleural Effusions term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase disease_progression ISO protein:decreased expression:serum:
protein:increased activity:serum:		 RGD PMID:27300446 PMID:1689629 PMID:1818842 RGD:152995272, RGD:152995292, RGD:152998934 NCBI chr 3:172,818,174...172,842,283
Ensembl chr 3:152,398,747...152,447,088 		JBrowse link
G Il10 interleukin 10 ISO RGD PMID:30695099 RGD:14975123 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Mmp2 matrix metallopeptidase 2 ISO associated with pleurisy; protein:decreased activity:pleura RGD PMID:17611666 RGD:5130711 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO associated with pleurisy; protein:decreased activity:pleura RGD PMID:17611666 RGD:5130711 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
malignant pleural mesothelioma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bap1 BRCA1 associated deubiquitinase 1 disease_progression ISO RGD PMID:27422796 RGD:127229946 NCBI chr16:6,453,126...6,461,952
Ensembl chr16:6,446,709...6,455,535 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 exacerbates ISO mRNA:increased expression:pleura, lung (human) RGD PMID:17253596 RGD:153344528 NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Birc7 baculoviral IAP repeat-containing 7 ameliorates ISO mRNA:increased expression:pleura, lung (human) RGD PMID:17253596 RGD:153344528 NCBI chr 3:188,425,392...188,430,174
Ensembl chr 3:168,047,824...168,052,606 		JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit ameliorates ISO RGD PMID:18722110 RGD:151667912 NCBI chr 1:126,123,425...126,249,181
Ensembl chr 1:116,714,711...116,837,240 		JBrowse link
G Csf1r colony stimulating factor 1 receptor ISO mRNA:increased expression:peritoneum�� (human) RGD PMID:24722292 RGD:150524278 NCBI chr18:56,834,152...56,860,804
Ensembl chr18:54,546,659...54,590,415 		JBrowse link
G Emx2 empty spiracles homeobox 2 exacerbates ISO mRNA:decreased expression:mesothelium of pleural cavity (human) RGD PMID:25023662 RGD:153323312 NCBI chr 1:258,626,584...258,633,594
Ensembl chr 1:258,626,584...258,633,594 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit disease_progression ISO mRNA, protein:increased expression:pleura RGD PMID:22028491 RGD:126781718 NCBI chr 4:77,624,223...77,698,598
Ensembl chr 4:76,624,399...76,687,362 		JBrowse link
G Il7r interleukin 7 receptor disease_progression ISO RGD PMID:26155428 RGD:151347688 NCBI chr 2:60,179,561...60,204,937
Ensembl chr 2:58,454,217...58,477,757 		JBrowse link
G Kdm6a lysine demethylase 6A ISO mRNA:increased expression:mesothelium of pleural cavity (human) RGD PMID:28197626 RGD:150429737 NCBI chr  X:6,920,374...7,060,027
Ensembl chr  X:4,337,750...4,477,062 		JBrowse link
G Mir192 microRNA 192 ISO miRNA:decreased expression:pleura (human) RGD PMID:26125439 RGD:11529530 NCBI chr 1:203,564,946...203,565,055
Ensembl chr 1:203,564,946...203,565,055 		JBrowse link
G Mir193a microRNA 193a ISO miRNA:decreased expression:pleura (human) RGD PMID:26125439 RGD:11529530 NCBI chr10:65,170,306...65,170,417
Ensembl chr10:64,672,343...64,672,454 		JBrowse link
G Mir200b microRNA 200b ISO miRNA:decreased expression:pleura (human) RGD PMID:26125439 RGD:11529530 NCBI chr 5:171,931,495...171,931,589
Ensembl chr 5:166,649,272...166,649,366 		JBrowse link
G Mlh1 mutL homolog 1 disease_progression ISO RGD PMID:23810210 RGD:126848799 NCBI chr 8:120,074,871...120,112,109
Ensembl chr 8:111,196,468...111,233,617 		JBrowse link
G Ncoa2 nuclear receptor coactivator 2 ameliorates ISO protein:increased expression:mesothelium of pleural cavity (human) RGD PMID:22011668 RGD:153002578 NCBI chr 5:10,618,712...10,852,776
Ensembl chr 5:5,835,706...6,067,451 		JBrowse link
G Nf2 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor disease_progression ISO DNA:loss of heterozygosity RGD PMID:27378628 PMID:26928227 PMID:26493618 RGD:150530638, RGD:150429647, RGD:11553131 NCBI chr14:83,850,894...83,934,263
Ensembl chr14:79,627,399...79,710,667 		JBrowse link
G Rad21 RAD21 cohesin complex component ISO RGD PMID:19380173 RGD:150520037 NCBI chr 7:85,177,715...85,204,657
Ensembl chr 7:83,287,870...83,314,817 		JBrowse link
G Setd2 SET domain containing 2, histone lysine methyltransferase disease_progression ISO DNA:mutations:CDS:multiple (human) RGD PMID:26928227 PMID:33691361 RGD:150429647, RGD:150520202 NCBI chr 8:119,390,207...119,475,863
Ensembl chr 8:110,511,772...110,597,489 		JBrowse link
G Slc7a5 solute carrier family 7 member 5 disease_progression ISO protein:increased expression:pleura RGD PMID:22199264 PMID:24912849 RGD:151361201, RGD:151660330 NCBI chr19:66,843,808...66,872,412
Ensembl chr19:49,935,220...49,963,823 		JBrowse link
G Smo smoothened, frizzled class receptor disease_progression ISO DNA:missense mutations RGD PMID:23379358 PMID:33209614 RGD:150521620, RGD:150521621 NCBI chr 4:59,311,084...59,341,280
Ensembl chr 4:58,343,529...58,373,829 		JBrowse link
G Xiap X-linked inhibitor of apoptosis ameliorates ISO mRNA:increased expression:pleura, lung (human) RGD PMID:17253596 RGD:153344528 NCBI chr  X:125,756,107...125,803,979
Ensembl chr  X:120,897,907...120,934,700 		JBrowse link
maxillary sinus squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn1a cyclin-dependent kinase inhibitor 1A ISO RGD PMID:15040115 RGD:8662355 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
nasal cavity adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clu clusterin ISO RGD PMID:19903339 RGD:9014708 NCBI chr15:44,336,619...44,375,861
Ensembl chr15:40,174,617...40,200,315 		JBrowse link
nasal cavity cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sox2 SRY-box transcription factor 2 ISO DNA:amplification RGD PMID:23544055 RGD:8661654 NCBI chr 2:119,465,131...119,467,542
Ensembl chr 2:117,536,929...117,539,338 		JBrowse link
G Tp53 tumor protein p53 ISO RGD PMID:19950227 RGD:8547762 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
nasal type extranodal NK/T-cell lymphoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A severity ISO Nasal Type;protein:increased expression:nasal cavity (human) RGD PMID:18756548 RGD:8657087 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Cd274 CD274 molecule disease_progression ISO associated with Epstein-Barr Virus Infections RGD PMID:27595782 RGD:41412182 NCBI chr 1:236,526,215...236,549,956
Ensembl chr 1:227,116,649...227,134,450 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:15924153 NCBI chr 9:67,679,502...67,747,226
Ensembl chr 9:60,185,452...60,237,034 		JBrowse link
G Fas Fas cell surface death receptor ISO DNA:insertion, deletions:cds:multiple (human) RGD PMID:12466128 RGD:8662407 NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Gpx3 glutathione peroxidase 3 treatment ISO associated with ethmoid sinus cancer and Neoplasm Metastasis RGD PMID:29496492 RGD:151708712 NCBI chr10:39,529,335...39,537,406
Ensembl chr10:39,028,570...39,037,035 		JBrowse link
G Jak3 Janus kinase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22705984 PMID:23689514 NCBI chr16:18,418,807...18,432,515
Ensembl chr16:18,386,405...18,398,536 		JBrowse link
G Prdm1 PR/SET domain 1 disease_progression ISO RGD PMID:24438193 RGD:150530467 NCBI chr20:49,542,465...49,564,088
Ensembl chr20:47,959,858...47,981,488 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO protein:increased expression:nasal cavity (human) RGD PMID:17225522 RGD:153298933 NCBI chr10:86,311,528...86,363,513
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Stat5b signal transducer and activator of transcription 5B ISO CTD Direct Evidence: marker/mechanism CTD PMID:29200404 NCBI chr10:86,205,148...86,276,178
Ensembl chr10:85,705,670...85,775,668 		JBrowse link
nasopharynx carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arid1a AT-rich interaction domain 1A disease_progression ISO protein:decreased expression:nasopharynx(human) RGD PMID:31213911 RGD:126781707 NCBI chr 5:151,192,014...151,269,291
Ensembl chr 5:145,908,181...145,985,564 		JBrowse link
G Atm ATM serine/threonine kinase treatment ISO protein:decreased expression:epithelium of nasopharynx (human)
associated with Epstein-Barr Virus Infections;mRNA:decreased expression:nasopharyngeal tissue (human)		 RGD PMID:29230817 PMID:19142888 PMID:28820634 RGD:126779560, RGD:126790562, RGD:150340692 NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Atr ATR serine/threonine kinase treatment ISO RGD PMID:28820634 RGD:150340692 NCBI chr 8:105,306,299...105,403,742
Ensembl chr 8:96,426,724...96,524,136 		JBrowse link
G Bcl2 BCL2, apoptosis regulator disease_progression ISO protein:increased expression:epithelium of nasopharynx (human) RGD PMID:12099337 RGD:11526103 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Brca1 BRCA1, DNA repair associated ISO DNA:nonsense mutation: :p.Q563* (human) RGD PMID:28857155 RGD:127229936 NCBI chr10:86,917,693...86,978,012
Ensembl chr10:86,418,000...86,477,304 		JBrowse link
G Btk Bruton tyrosine kinase ISO mRNA:decreased expression:nasopharynx (human) RGD PMID:33096113 RGD:151347855 NCBI chr  X:102,016,070...102,055,448
Ensembl chr  X:97,722,802...97,761,853 		JBrowse link
G Calr calreticulin exacerbates
disease_progression		 ISO protein:increased expression:epithelium of nasopharynx (human) RGD PMID:31632490 PMID:31956372 RGD:150520157, RGD:150521689 NCBI chr19:40,213,367...40,218,262
Ensembl chr19:23,308,351...23,313,414 		JBrowse link
G Ccnd2 cyclin D2 disease_progression ISO RGD PMID:20473882 RGD:151665334 NCBI chr 4:161,653,048...161,675,422
Ensembl chr 4:159,962,363...159,989,495 		JBrowse link
G Cd163 CD163 molecule exacerbates ISO protein:increased expression:nasopharynx, macrophage (human) RGD PMID:28395580 RGD:127285800 NCBI chr 4:158,770,751...158,804,146
Ensembl chr 4:157,085,093...157,117,878 		JBrowse link
G Chrna5 cholinergic receptor nicotinic alpha 5 subunit susceptibility ISO DNA:SNP: :rs3841324(human) RGD PMID:25329654 RGD:150527838 NCBI chr 8:64,265,879...64,294,233
Ensembl chr 8:55,369,794...55,398,146 		JBrowse link
G Clptm1l CLPTM1-like susceptibility ISO DNA:SNP: :rs401681(human)
protein:increased expression:nasopharynx
DNA:SNP:intron:rs31489(human) 		RGD PMID:26621837 PMID:26621837 PMID:26545403 PMID:31270100 RGD:11564613, RGD:11564613, RGD:11556976, RGD:150537099 NCBI chr 1:31,496,094...31,512,148
Ensembl chr 1:29,667,545...29,683,530 		JBrowse link
G Cr2 complement C3d receptor 2 susceptibility ISO DNA:SNP:5'UTR:24T>C (rs3813946)(human) RGD PMID:23612877 RGD:127338247 NCBI chr13:109,207,034...109,244,980
Ensembl chr13:106,685,413...106,716,235 		JBrowse link
G Csf1r colony stimulating factor 1 receptor treatment ISO RGD PMID:22267178 RGD:150524299 NCBI chr18:56,834,152...56,860,804
Ensembl chr18:54,546,659...54,590,415 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 disease_progression
exacerbates		 ISO mRNA:increased expression:nasopharynx (human)
protein:increased expression:nasopharynx (human)		 RGD PMID:26611644 PMID:15978137 RGD:152023644, RGD:152177484 NCBI chr13:42,630,383...42,634,288
Ensembl chr13:40,077,976...40,081,883 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 ISO DNA:SNP: :rs2031920 (human) RGD PMID:26582733 RGD:11061495 NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Dab2ip DAB2 interacting protein disease_progression ISO mRNA,protein:decreased expression:epithelium of nasopharynx (human) RGD PMID:28586035 RGD:151665144 NCBI chr 3:39,312,745...39,483,730
Ensembl chr 3:18,915,290...19,086,280 		JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 ISO mRNA:increased expression:epithelium of nasopharynx RGD PMID:18023033 RGD:150429715 NCBI chr13:84,726,412...84,851,032
Ensembl chr13:82,195,463...82,317,363 		JBrowse link
G Efnb2 ephrin B2 disease_progression ISO protein:increased expression:nasopharynx (human) RGD PMID:23631129 RGD:153305949 NCBI chr16:87,485,215...87,529,224
Ensembl chr16:80,783,417...80,824,391 		JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 disease_progression ISO RGD PMID:24825912 RGD:126781774 NCBI chr 7:1,579,079...1,600,379
Ensembl chr 7:996,225...1,015,525 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit disease_progression ISO mRNA, protein:increased expression:ventral nasal meatus RGD PMID:21300475 RGD:126779603 NCBI chr 4:77,624,223...77,698,598
Ensembl chr 4:76,624,399...76,687,362 		JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 severity ISO protein:increased expression:nasopharynx (human) RGD PMID:26535066 RGD:150520063 NCBI chr17:9,466,686...9,481,423
Ensembl chr17:9,461,547...9,476,242 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 disease_progression ISO RGD PMID:16480593 RGD:126925191 NCBI chr12:12,333,050...12,504,750
Ensembl chr12:7,297,292...7,468,626 		JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit ISO mRNA:increased expression:nasopharynx (human) RGD PMID:30326930 RGD:153344557 NCBI chr 6:30,017,952...30,039,269
Ensembl chr 6:24,300,956...24,320,034 		JBrowse link
G Fubp1 far upstream element binding protein 1 exacerbates ISO protein:increased expression:nasopharynx (human) RGD PMID:26469968 RGD:11343512 NCBI chr 2:243,819,529...243,846,544
Ensembl chr 2:241,159,512...241,186,602 		JBrowse link
G Gpx1 glutathione peroxidase 1 susceptibility ISO DNA:missense mutation:CDS:p.P198L (human) RGD PMID:33616746 RGD:152995452 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A ISO protein:decreased expression:nasopharynx (human) RGD PMID:26681223 RGD:150539449 NCBI chr10:6,136,458...6,560,003
Ensembl chr10:5,631,369...6,044,637 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 no_association ISO DNA:SNP: :1270533T>G (human) RGD PMID:24711137 PMID:19448408 RGD:14700933, RGD:14700955 NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Jak2 Janus kinase 2 severity ISO protein:increased expression:mucosa of nasopharynx (human) RGD PMID:30123088 RGD:149735327 NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Kdm3a lysine demethylase 3A severity ISO protein:decreased expression:nasopharyngeal epithelium (human) RGD PMID:21541331 RGD:9590228 NCBI chr 4:105,189,208...105,233,526
Ensembl chr 4:103,630,908...103,675,073 		JBrowse link
G Kdr kinase insert domain receptor disease_progression ISO RGD PMID:16480593 RGD:126925191 NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,217,871...32,261,018 		JBrowse link
G Kmt2c lysine methyltransferase 2C ISO RGD PMID:31646828 RGD:151356762 NCBI chr 4:10,353,698...10,755,965
Ensembl chr 4:9,609,627...9,833,539 		JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 ameliorates ISO DNA:SNP:promoter: -1304T>G, -1304G>G (human)
associated with Epstein-Barr Virus Infections; DNA:SNPs:promoter: -1304G>G, -1304T>G (human)		 RGD PMID:27373035 PMID:21702039 RGD:150429759, RGD:150429763 NCBI chr10:50,842,348...50,947,063
Ensembl chr10:50,344,915...50,447,993 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 treatment ISO human cell line in a mouse model RGD PMID:32449282 RGD:151665502 NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,749,670...6,810,589 		JBrowse link
G Mir132 microRNA 132 treatment ISO RGD PMID:29442000 RGD:151665745 NCBI chr10:60,522,033...60,522,133
Ensembl chr10:60,023,696...60,023,796 		JBrowse link
G Mir152 microRNA 152 ISO miRNA:decreased expression:nasopharynx RGD PMID:28000885 RGD:19165149 NCBI chr10:82,329,383...82,329,467
Ensembl chr10:81,832,936...81,833,020 		JBrowse link
G Mir154 microRNA 154 disease_progression ISO RNA:decreased expression:epithelium of nasopharynx (human) RGD PMID:32214824 RGD:152995464 NCBI chr 6:134,574,352...134,574,435
Ensembl chr 6:128,752,947...128,753,030 		JBrowse link
G Mir222 microRNA 222 ISO RNA:increased expression:nasopharynx RGD PMID:29115464 RGD:151708744 NCBI chr  X:6,022,621...6,022,723
Ensembl chr  X:3,428,904...3,429,006 		JBrowse link
G Mir31 microRNA 31 disease_progression
ameliorates		 ISO RNA:decreased expression:peripheral blood mononuclear cell (human)
Human cells in mouse model		 RGD PMID:31129965 PMID:25098679 RGD:152998936, RGD:152998921 NCBI chr 5:108,714,849...108,714,954 JBrowse link
G Mir423 microRNA 423 disease_progression ISO mRNA:decreased expression:nasopharynx (human) RGD PMID:30326930 RGD:153344557 NCBI chr10:62,412,272...62,412,350
Ensembl chr10:61,914,133...61,914,226 		JBrowse link
G Mst1r macrophage stimulating 1 receptor susceptibility ISO ClinVar Annotator: match by term: MST1R-related condition | ClinVar Annotator: match by term: Nasopharyngeal carcinoma, susceptibility to, 3 OMIM
ClinVar		 PMID:25741868 PMID:26951679 PMID:28492532 NCBI chr 8:117,471,928...117,491,059
Ensembl chr 8:108,597,299...108,612,455 		JBrowse link
G Muc5b mucin 5B, oligomeric mucus/gel-forming IEP RGD PMID:19068094 RGD:2325214 NCBI chr 1:206,346,400...206,378,367
Ensembl chr 1:196,916,825...196,949,250 		JBrowse link
G Npc1 NPC intracellular cholesterol transporter 1 ISO ClinVar Annotator: match by term: Nasopharyngeal carcinoma ClinVar PMID:10480349 PMID:11182931 PMID:11333381 PMID:11349231 PMID:12408188 More... NCBI chr18:3,654,237...3,699,853
Ensembl chr18:3,379,482...3,425,049 		JBrowse link
G Ppia peptidylprolyl isomerase A ISO mRNA, protein:increased expression:blood serum, nasopharynx, extracellular exosome (human) RGD PMID:31063269 RGD:150429622 NCBI chr14:85,491,223...85,496,884
Ensembl chr14:81,275,091...81,299,601 		JBrowse link
G Rac1 Rac family small GTPase 1 exacerbates ISO protein:increased expression:nasopharynx (human) RGD PMID:19506399 RGD:153350125 NCBI chr12:16,150,411...16,170,864
Ensembl chr12:11,036,698...11,057,251 		JBrowse link
G Rad52 RAD52 homolog, DNA repair protein severity ISO protein:increased expression:nasopharynx (human) RGD PMID:25026830 RGD:151361208 NCBI chr 4:154,778,320...154,802,002
Ensembl chr 4:153,106,062...153,128,207 		JBrowse link
G Snrpd1 small nuclear ribonucleoprotein D1 polypeptide ISO mRNA:increased expression:nasopharynx (human) RGD PMID:24080422 RGD:10755709 NCBI chr18:1,969,351...1,980,207
Ensembl chr18:1,696,852...1,708,256 		JBrowse link
G Snrpe small nuclear ribonucleoprotein polypeptide E ISO mRNA:increased expression:nasopharynx (human) RGD PMID:24080422 RGD:10755709 NCBI chr13:47,596,324...47,609,390
Ensembl chr13:45,050,986...45,057,310
Ensembl chr 8:45,050,986...45,057,310 		JBrowse link
G Snrpf small nuclear ribonucleoprotein polypeptide F ISO mRNA:increased expression:nasopharynx (human) RGD PMID:24080422 RGD:10755709 NCBI chr 7:30,017,460...30,024,162
Ensembl chr 7:28,130,427...28,137,129 		JBrowse link
G Snrpg small nuclear ribonucleoprotein polypeptide G ISO mRNA:increased expression:nasopharynx (human) RGD PMID:24080422 RGD:10755709 NCBI chr 4:120,369,676...120,377,263
Ensembl chr 4:118,812,252...118,819,826
Ensembl chr  X:118,812,252...118,819,826 		JBrowse link
G Spen spen family transcriptional repressor disease_progression ISO protein:increased expression:mucosa of nasopharynx (human) RGD PMID:32641685 RGD:151347437 NCBI chr 5:159,058,258...159,131,789
Ensembl chr 5:153,776,234...153,848,811 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase disease_progression ISO RGD PMID:27078847 RGD:150521726 NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 severity ISO protein:increased expression:mucosa of nasopharynx (human) RGD PMID:30123088 RGD:149735327 NCBI chr10:86,311,528...86,363,513
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Tert telomerase reverse transcriptase ISO protein:increased expression:nasopharynx RGD PMID:26621837 RGD:11564613 NCBI chr 1:31,465,766...31,488,650
Ensembl chr 1:29,637,506...29,659,561 		JBrowse link
G Tet2 tet methylcytosine dioxygenase 2 severity ISO human cells in mouse model RGD PMID:32774157 RGD:150429610 NCBI chr 2:224,662,654...224,746,819
Ensembl chr 2:221,988,645...222,072,534 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 treatment ISO RGD PMID:26149137 RGD:151347434 NCBI chr 1:15,528,921...15,543,993
Ensembl chr 1:13,709,206...13,725,282 		JBrowse link
G Tp53 tumor protein p53 ISO ClinVar Annotator: match by term: Nasopharyngeal carcinoma ClinVar
OMIM
RGD		 PMID:1565143 PMID:1565144 PMID:1591732 PMID:1631137 PMID:1631151 More... RGD:8547825 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Vegfa vascular endothelial growth factor A disease_progression
severity		 ISO protein:increased expression:mucosa of nasopharynx (human)
protein:increased expression:nasopharynx (human)		 RGD PMID:16480593 PMID:30123088 PMID:23631129 RGD:126925191, RGD:149735327, RGD:153305949 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Wrap53 WD repeat containing, antisense to TP53 ISO associated with Epstein-Barr Virus Infections; protein:increased expression:nasopharynx epithelium RGD PMID:28607398 RGD:21081524 NCBI chr10:54,780,873...54,797,919
Ensembl chr10:54,282,105...54,298,929 		JBrowse link
G Xrcc1 X-ray repair cross complementing 1 treatment
sexual_dimorphism
susceptibility		 ISO DNA:SNP:3'utr: (rs25489) (human)
DNA:missense mutation:cds: p.R194W (human)
associated with Tobacco Use Disorder; DNA:missense mutation:cds: p.R399Q (human)
DNA:missense mutation:exon 10: p.R399Q G>A, (rs25487) (human)		 RGD PMID:29108254 PMID:16796765 PMID:27356695 PMID:24175791 PMID:17630853 RGD:150530619, RGD:150573694, RGD:150573697, RGD:150573698, RGD:150573708 NCBI chr 1:89,268,721...89,296,619
Ensembl chr 1:80,141,207...80,168,701 		JBrowse link
Nose Neoplasms term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dmbt1 deleted in malignant brain tumors 1 IEP mRNA, Protein:increased expression RGD PMID:12419858 RGD:1599782 NCBI chr 1:195,047,702...195,126,704
Ensembl chr 1:185,617,294...185,696,478 		JBrowse link
G Mmp2 matrix metallopeptidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16178123 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
paranasal sinus benign neoplasm term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa1 annexin A1 ISO RGD PMID:20970165 RGD:7421559 NCBI chr 1:227,287,713...227,306,739
Ensembl chr 1:217,861,175...217,877,343 		JBrowse link
G Anxa2 annexin A2 disease_progression ISO RGD PMID:20970165 RGD:7421559 NCBI chr 8:78,986,252...79,022,638
Ensembl chr 8:70,105,253...70,141,658 		JBrowse link
G Tp53 tumor protein p53 treatment ISO DNA:mutations:cds: RGD PMID:22575263 PMID:23369851 RGD:8547763, RGD:8547764 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
peritoneal mesothelioma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lats1 large tumor suppressor kinase 1 ISO ClinVar Annotator: match by term: Malignant peritoneal mesothelioma ClinVar NCBI chr 1:3,980,801...4,014,029
Ensembl chr 1:2,160,411...2,193,640 		JBrowse link
G Lats2 large tumor suppressor kinase 2 ISO ClinVar Annotator: match by term: Malignant peritoneal mesothelioma ClinVar NCBI chr15:35,940,632...35,992,225
Ensembl chr15:31,825,092...31,877,220 		JBrowse link
G Mecom MDS1 and EVI1 complex locus ISO ClinVar Annotator: match by term: Malignant peritoneal mesothelioma ClinVar NCBI chr 2:114,837,815...115,393,052
Ensembl chr 2:112,909,321...113,464,590 		JBrowse link
G Traf7 TNF receptor associated factor 7 ISO DNA:missense mutations:multiple RGD PMID:30171198 RGD:151356964 NCBI chr10:14,038,117...14,056,832
Ensembl chr10:13,533,570...13,552,203 		JBrowse link
Pleural Neoplasms term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nf2 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor ISO CTD Direct Evidence: marker/mechanism CTD PMID:23435014 NCBI chr14:83,850,894...83,934,263
Ensembl chr14:79,627,399...79,710,667 		JBrowse link
G Spp1 secreted phosphoprotein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16221779 NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
pleuropulmonary blastoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asb2 ankyrin repeat and SOCS box-containing 2 ISO ClinVar Annotator: match by term: DICER1-related pleuropulmonary blastoma cancer predisposition syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:128,239,550...128,275,833
Ensembl chr 6:122,474,756...122,510,854 		JBrowse link
G Btbd7 BTB domain containing 7 ISO ClinVar Annotator: match by term: DICER1-related pleuropulmonary blastoma cancer predisposition syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:127,685,185...127,774,947
Ensembl chr 6:121,923,023...121,972,405 		JBrowse link
G Cox8c cytochrome c oxidase subunit 8C ISO ClinVar Annotator: match by term: DICER1-related pleuropulmonary blastoma cancer predisposition syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:127,793,379...127,794,702
Ensembl chr 6:122,028,566...122,029,889 		JBrowse link
G Ddx24 DEAD-box helicase 24 ISO ClinVar Annotator: match by term: DICER1-related pleuropulmonary blastoma cancer predisposition syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:128,329,554...128,346,818
Ensembl chr 6:122,564,767...122,581,927 		JBrowse link
G Dicer1 dicer 1 ribonuclease III ISO ClinVar Annotator: match by term: DICER1-related pleuropulmonary blastoma cancer predisposition syndrome | ClinVar Annotator: match by term: Pleuropulmonary blastoma
CTD Direct Evidence: marker/mechanism
DNA:mutations:cds		 ClinVar
CTD
RGD		 PMID:9295070 PMID:9345104 PMID:9536098 PMID:15242644 PMID:15987463 More... RGD:149735200, RGD:11552609 NCBI chr 6:129,392,298...129,457,252
Ensembl chr 6:123,631,250...123,693,965 		JBrowse link
G Fam181a family with sequence similarity 181, member A ISO ClinVar Annotator: match by term: DICER1-related pleuropulmonary blastoma cancer predisposition syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:128,230,171...128,236,193
Ensembl chr 6:122,465,391...122,471,397 		JBrowse link
G Fgf9 fibroblast growth factor 9 ISS MouseDO NCBI chr15:36,325,552...36,369,995
Ensembl chr15:32,210,074...32,253,309 		JBrowse link
G Gsc goosecoid homeobox ISO ClinVar Annotator: match by term: DICER1-related pleuropulmonary blastoma cancer predisposition syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:129,152,836...129,154,875
Ensembl chr 6:123,388,072...123,390,111 		JBrowse link
G Ifi27 interferon, alpha-inducible protein 27 ISO ClinVar Annotator: match by term: DICER1-related pleuropulmonary blastoma cancer predisposition syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:128,355,312...128,361,783
Ensembl chr 6:122,590,472...122,779,294 		JBrowse link
G Ifi27l2a interferon, alpha-inducible protein 27 like 2A ISO ClinVar Annotator: match by term: DICER1-related pleuropulmonary blastoma cancer predisposition syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:128,363,658...128,365,144
Ensembl chr 6:122,598,872...122,600,360 		JBrowse link
G Otub2 OTU deubiquitinase, ubiquitin aldehyde binding 2 ISO ClinVar Annotator: match by term: DICER1-related pleuropulmonary blastoma cancer predisposition syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:128,309,863...128,328,444
Ensembl chr 6:122,545,061...122,563,644 		JBrowse link
G Ppp4r4 protein phosphatase 4, regulatory subunit 4 ISO ClinVar Annotator: match by term: DICER1-related pleuropulmonary blastoma cancer predisposition syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:128,427,884...128,518,776
Ensembl chr 6:122,663,344...122,753,384 		JBrowse link
G Prima1 proline rich membrane anchor 1 ISO ClinVar Annotator: match by term: DICER1-related pleuropulmonary blastoma cancer predisposition syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:128,094,686...128,155,592
Ensembl chr 6:122,338,370...122,389,921 		JBrowse link
G Serpina1 serpin family A member 1 ISO ClinVar Annotator: match by term: DICER1-related pleuropulmonary blastoma cancer predisposition syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:128,631,101...128,653,125
Ensembl chr 6:122,866,312...122,888,339 		JBrowse link
G Serpina10 serpin family A member 10 ISO ClinVar Annotator: match by term: DICER1-related pleuropulmonary blastoma cancer predisposition syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:128,520,894...128,529,332
Ensembl chr 6:122,756,108...122,764,544 		JBrowse link
G Serpina11 serpin family A member 11 ISO ClinVar Annotator: match by term: DICER1-related pleuropulmonary blastoma cancer predisposition syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:128,668,030...128,677,476
Ensembl chr 6:122,903,250...122,912,670 		JBrowse link
G Serpina12 serpin family A member 12 ISO ClinVar Annotator: match by term: DICER1-related pleuropulmonary blastoma cancer predisposition syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:128,717,334...128,732,049
Ensembl chr 6:122,952,552...122,967,271 		JBrowse link
G Serpina1f serpin family A member 1F ISO ClinVar Annotator: match by term: DICER1-related pleuropulmonary blastoma cancer predisposition syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:128,585,697...128,591,902
Ensembl chr 6:122,820,907...122,827,112 		JBrowse link
G Serpina3n serpin family A member 3N ISO ClinVar Annotator: match by term: DICER1-related pleuropulmonary blastoma cancer predisposition syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:129,088,392...129,095,950
Ensembl chr 6:123,323,629...123,332,433 		JBrowse link
G Serpina4 serpin family A member 4 ISO ClinVar Annotator: match by term: DICER1-related pleuropulmonary blastoma cancer predisposition syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:128,764,738...128,773,858
Ensembl chr 6:122,999,900...123,009,082 		JBrowse link
G Serpina5 serpin family A member 5 ISO ClinVar Annotator: match by term: DICER1-related pleuropulmonary blastoma cancer predisposition syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:128,774,006...128,793,187
Ensembl chr 6:123,023,306...123,028,407 		JBrowse link
G Serpina6 serpin family A member 6 ISO ClinVar Annotator: match by term: DICER1-related pleuropulmonary blastoma cancer predisposition syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:128,544,828...128,555,064
Ensembl chr 6:122,780,043...122,790,349 		JBrowse link
G Serpina9 serpin family A member 9 ISO ClinVar Annotator: match by term: DICER1-related pleuropulmonary blastoma cancer predisposition syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:122,918,819...122,936,000
Ensembl chr 6:122,918,880...122,936,000 		JBrowse link
G Ubr7 ubiquitin protein ligase E3 component n-recognin 7 ISO ClinVar Annotator: match by term: DICER1-related pleuropulmonary blastoma cancer predisposition syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:127,663,454...127,683,302
Ensembl chr 6:121,898,623...121,918,477 		JBrowse link
G Unc79 unc-79 homolog, NALCN channel complex subunit ISO ClinVar Annotator: match by term: DICER1-related pleuropulmonary blastoma cancer predisposition syndrome ClinVar PMID:26545620 PMID:26555935 PMID:28492532 NCBI chr 6:127,841,671...128,092,380
Ensembl chr 6:122,080,308...122,327,591 		JBrowse link
G Yy1 YY1 transcription factor ISS OMIM:601200 MouseDO NCBI chr 6:133,471,615...133,500,875
Ensembl chr 6:127,707,596...127,732,747 		JBrowse link
pulmonary neuroendocrine tumor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rnaset2 ribonuclease T2 ISO mRNA:increased expression:lung (human) RGD PMID:29763721 RGD:153002569 NCBI chr 1:52,576,344...52,603,151
Ensembl chr 1:52,585,929...52,603,147 		JBrowse link
G Srsf2 serine and arginine rich splicing factor 2 ISO mRNA, protein:increased expression:lung (human) RGD PMID:23518498 RGD:11039050 NCBI chr10:102,550,962...102,554,200
Ensembl chr10:102,052,314...102,055,338 		JBrowse link
pulmonary venoocclusive disease 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr2 bone morphogenetic protein receptor type 2 ISO ClinVar Annotator: match by term: Familial pulmonary capillary hemangiomatosis ClinVar PMID:18626305 PMID:24292273 NCBI chr 9:68,685,942...68,801,353
Ensembl chr 9:61,190,566...61,301,809 		JBrowse link
G Eif2ak4 eukaryotic translation initiation factor 2 alpha kinase 4 ISO ClinVar Annotator: match by term: EIF2AK4-related condition | ClinVar Annotator: match by term: Familial pulmonary capillary hemangiomatosis OMIM
ClinVar		 PMID:12215525 PMID:24033266 PMID:24135949 PMID:24292273 PMID:24310610 More... NCBI chr 3:125,810,207...125,895,574
Ensembl chr 3:105,356,261...105,441,630 		JBrowse link
sarcomatoid mesothelioma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn2a cyclin-dependent kinase inhibitor 2A IAGP DNA:deletion RGD PMID:20065947 RGD:7248760 NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
sinonasal undifferentiated carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Maml3 mastermind-like transcriptional coactivator 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24859338 NCBI chr 2:137,871,267...138,288,615
Ensembl chr 2:135,721,021...136,137,814 		JBrowse link
G Pax3 paired box 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24859338 NCBI chr 9:87,015,960...87,112,531
Ensembl chr 9:79,568,634...79,664,042 		JBrowse link
G Smarcb1 SWI/SNF related BAF chromatin remodeling complex subunit B1 ISO RGD PMID:30120966 RGD:127285653 NCBI chr20:12,740,105...12,763,054
Ensembl chr20:12,741,477...12,763,620 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19140
    disease of anatomical entity 18453
      respiratory system disease 5243
        Respiratory Tract Neoplasms 1016
          Laryngeal Neoplasms + 50
          Lung Neoplasms + 991
          Nose Neoplasms + 20
          Pleural Neoplasms + 25
          respiratory system benign neoplasm + 5
          respiratory system cancer + 803
          tracheal neoplasm + 0
Path 2
Term Annotations click to browse term
  disease 19140
    disease of anatomical entity 18453
      respiratory system disease 5243
        thoracic disease 4046
          Thoracic Neoplasms 1020
            Respiratory Tract Neoplasms 1016
              Laryngeal Neoplasms + 50
              Lung Neoplasms + 991
              Nose Neoplasms + 20
              Pleural Neoplasms + 25
              respiratory system benign neoplasm + 5
              respiratory system cancer + 803
              tracheal neoplasm + 0
paths to the root