BRAF (B-Raf proto-oncogene, serine/threonine kinase) - Rat Genome Database

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Gene: BRAF (B-Raf proto-oncogene, serine/threonine kinase) Canis lupus familiaris
Analyze
Symbol: BRAF
Name: B-Raf proto-oncogene, serine/threonine kinase
RGD ID: 12185039
Description: ENCODES a protein that exhibits MAP kinase kinase kinase activity (ortholog); mitogen-activated protein kinase kinase binding (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN alpha-beta T cell differentiation (ortholog); CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (ortholog); CD4-positive, alpha-beta T cell differentiation (ortholog); PARTICIPATES IN adenosine signaling pathway; altered extracellular signal-regulated Raf/Mek/Erk signaling pathway; colorectal cancer pathway; ASSOCIATED WITH transitional cell carcinoma; adrenocortical carcinoma (ortholog); ameloblastoma (ortholog); FOUND IN cell body (inferred); cytoplasm (inferred); cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: B-raf protein; serine/threonine-protein kinase B-raf; v-raf murine sarcoma viral oncogene homolog B1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1168,222,909 - 8,318,179 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl168,222,907 - 8,317,906 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha168,989,501 - 9,160,850 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0168,065,738 - 8,237,942 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl168,065,737 - 8,239,141 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1168,017,140 - 8,188,930 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0167,861,588 - 8,033,660 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0167,929,505 - 8,101,841 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
adrenocortical carcinoma  (ISO)
ameloblastoma  (ISO)
Aortic Aneurysm, Giant Congenital  (ISO)
arteriovenous malformations of the brain  (ISO)
ataxia telangiectasia  (ISO)
B-Cell Chronic Lymphocytic Leukemia  (ISO)
bile duct adenoma  (ISO)
Brain Neoplasms  (ISO)
Breast Neoplasms  (ISO)
cancer  (ISO)
Carcinogenesis  (ISO)
cardiofaciocutaneous syndrome  (ISO)
cardiofaciocutaneous syndrome 1  (ISO)
cardiomyopathy  (ISO)
cholangiocarcinoma  (ISO)
chronic lymphocytic leukemia  (ISO)
chronic myelogenous leukemia, BCR-ABL1 positive  (ISO)
chronic myeloid leukemia  (ISO)
colon carcinoma  (ISO)
Colonic Neoplasms  (ISO)
colorectal adenocarcinoma  (ISO)
colorectal cancer  (ISO)
Colorectal Neoplasms  (ISO)
Costello syndrome  (ISO)
craniopharyngioma  (ISO)
Dandy-Walker syndrome  (ISO)
Developmental Disabilities  (ISO)
diffuse large B-cell lymphoma  (ISO)
dilated cardiomyopathy  (ISO)
disease of cellular proliferation  (ISO)
dysembryoplastic neuroepithelial tumor  (ISO)
dysplastic nevus syndrome  (ISO)
endometrial carcinoma  (ISO)
Experimental Melanoma  (ISO)
Experimental Neoplasms  (ISO)
familial melanoma  (ISO)
Follicular Thyroid Cancer  (ISO)
gallbladder cancer  (ISO)
ganglioglioma  (ISO)
gastric adenocarcinoma  (ISO)
gastrointestinal stromal tumor  (ISO)
genetic disease  (ISO)
germinoma  (ISO)
glioblastoma  (ISO)
head and neck squamous cell carcinoma  (ISO)
hepatocellular carcinoma  (ISO)
high grade glioma  (ISO)
hypertrophic cardiomyopathy  (ISO)
hypertrophic cardiomyopathy 4  (ISO)
intellectual disability  (ISO)
intrahepatic cholangiocarcinoma  (ISO)
Kidney Neoplasms  (ISO)
Langerhans-cell histiocytosis  (ISO)
Liver Metastasis  (ISO)
Liver Neoplasms  (ISO)
lung adenocarcinoma  (ISO)
lung cancer  (ISO)
lung carcinoma  (ISO)
Lung Neoplasms  (ISO)
lung non-small cell carcinoma  (ISO)
lung squamous cell carcinoma  (ISO)
lymphangioma  (ISO)
Lymphatic Metastasis  (ISO)
malignant astrocytoma  (ISO)
Mandibular Neoplasms  (ISO)
melanoma  (ISO)
Microsatellite Instability  (ISO)
multiple myeloma  (ISO)
myoepithelioma  (ISO)
Neoplasm Metastasis  (ISO)
nephroblastoma  (ISO)
neuroendocrine tumor  (ISO)
Nevus  (ISO)
newborn respiratory distress syndrome  (ISO)
non-Hodgkin lymphoma  (ISO)
Nonseminomatous Germ Cell Tumor  (ISO)
Noonan syndrome  (ISO)
Noonan syndrome 1  (ISO)
Noonan syndrome 7  (ISO)
Noonan syndrome with multiple lentigines  (ISO)
Noonan syndrome with multiple lentigines 3  (ISO)
Ovarian Neoplasms  (ISO)
ovarian serous cystadenocarcinoma  (ISO)
pancreatic acinar cell adenocarcinoma  (ISO)
pancreatic cancer  (ISO)
papillary renal cell carcinoma  (ISO)
Paraproteinemias  (ISO)
PHACE Association  (ISO)
plasma cell neoplasm  (ISO)
pleomorphic xanthoastrocytoma  (ISO)
Premature Birth  (ISO)
primary cutaneous T-cell non-Hodgkin lymphoma  (ISO)
prostate adenocarcinoma  (ISO)
Prostate Cancer, Hereditary, 1  (ISO)
Prostatic Neoplasms  (ISO)
pulmonary valve stenosis  (ISO)
RASopathy  (ISO)
Sezary's disease  (ISO)
skin melanoma  (ISO)
Sporadic Papillary Renal Cell Carcinoma  (ISO)
tethered spinal cord syndrome  (ISO)
thyroid gland papillary carcinoma  (ISO)
Thyroid Neoplasms  (ISO)
transitional cell carcinoma  (IAGP,ISO)
type 2 diabetes mellitus  (ISO)
uterine cancer  (ISO)
Vascular Malformations  (ISO)
ventricular septal defect  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
alpha-beta T cell differentiation  (IEA,ISO)
CD4-positive or CD8-positive, alpha-beta T cell lineage commitment  (IEA,ISO)
CD4-positive, alpha-beta T cell differentiation  (IEA,ISO)
cell differentiation  (IEA,ISO)
cellular response to calcium ion  (IEA)
cellular response to nerve growth factor stimulus  (ISO)
cellular response to xenobiotic stimulus  (IEA,ISO)
endothelial cell apoptotic process  (IEA,ISO)
epidermal growth factor receptor signaling pathway  (IEA)
ERK1 and ERK2 cascade  (IEA,ISO)
establishment of protein localization to membrane  (IEA)
face development  (IEA,ISO)
head morphogenesis  (IEA,ISO)
long-term synaptic potentiation  (IEA,ISO)
MAPK cascade  (IEA)
myeloid progenitor cell differentiation  (IEA,ISO)
negative regulation of apoptotic process  (IEA)
negative regulation of endothelial cell apoptotic process  (IEA,ISO)
negative regulation of fibroblast migration  (IEA,ISO)
negative regulation of neuron apoptotic process  (IEA,ISO)
negative regulation of synaptic vesicle exocytosis  (IEA,ISO)
positive regulation of axon regeneration  (IEA,ISO)
positive regulation of axonogenesis  (IEA,ISO)
positive regulation of ERK1 and ERK2 cascade  (IEA,ISO)
positive regulation of gene expression  (IEA,ISO)
positive regulation of glucose transmembrane transport  (IEA)
positive regulation of peptidyl-serine phosphorylation  (IEA)
positive regulation of stress fiber assembly  (IEA,ISO)
positive regulation of substrate adhesion-dependent cell spreading  (IEA,ISO)
positive T cell selection  (IEA,ISO)
protein phosphorylation  (ISO)
Ras protein signal transduction  (IEA)
regulation of axon regeneration  (IEA,ISO)
regulation of cell population proliferation  (IEA,ISO)
regulation of T cell differentiation  (IEA,ISO)
response to cAMP  (ISO)
response to peptide hormone  (ISO)
signal transduction  (IEA)
somatic stem cell population maintenance  (IEA,ISO)
stress fiber assembly  (IEA,ISO)
substrate adhesion-dependent cell spreading  (IEA,ISO)
synaptic vesicle exocytosis  (IEA,ISO)
T cell differentiation in thymus  (IEA,ISO)
T cell receptor signaling pathway  (IEA,ISO)
thymus development  (IEA,ISO)
thyroid gland development  (IEA,ISO)
trehalose metabolism in response to stress  (IEA)
visual learning  (IEA,ISO)

Cellular Component

References
Additional References at PubMed
PMID:15834638   PMID:21203559   PMID:22301074   PMID:26053201   PMID:30032202   PMID:30541168   PMID:31048548   PMID:32385388   PMID:33205710   PMID:33926328  


Genomics

Comparative Map Data
BRAF
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1168,222,909 - 8,318,179 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl168,222,907 - 8,317,906 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha168,989,501 - 9,160,850 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0168,065,738 - 8,237,942 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl168,065,737 - 8,239,141 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1168,017,140 - 8,188,930 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0167,861,588 - 8,033,660 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0167,929,505 - 8,101,841 (+)NCBIUU_Cfam_GSD_1.0
BRAF
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387140,713,328 - 140,924,929 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7140,719,327 - 140,924,929 (-)EnsemblGRCh38hg38GRCh38
GRCh377140,413,128 - 140,624,729 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367140,080,751 - 140,271,033 (-)NCBINCBI36Build 36hg18NCBI36
Build 347139,887,462 - 140,077,748NCBI
Celera7135,155,867 - 135,346,614 (-)NCBICelera
Cytogenetic Map7q34NCBI
HuRef7134,729,459 - 134,920,529 (-)NCBIHuRef
CHM1_17140,368,045 - 140,559,148 (-)NCBICHM1_1
T2T-CHM13v2.07142,027,505 - 142,239,131 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27139,771,989 - 139,962,886 (-)NCBI
Braf
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39639,580,171 - 39,702,592 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl639,580,171 - 39,702,397 (-)EnsemblGRCm39 Ensembl
GRCm38639,603,231 - 39,725,658 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl639,603,237 - 39,725,463 (-)EnsemblGRCm38mm10GRCm38
MGSCv37639,553,236 - 39,675,462 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36639,557,807 - 39,675,462 (-)NCBIMGSCv36mm8
Celera639,588,093 - 39,710,723 (-)NCBICelera
Cytogenetic Map6B1NCBI
cM Map618.43NCBI
Braf
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8469,329,772 - 69,476,931 (-)NCBIGRCr8
mRatBN7.2468,375,484 - 68,510,652 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl468,384,649 - 68,510,463 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0467,389,331 - 67,520,549 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl467,396,192 - 67,520,356 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0467,196,477 - 67,327,649 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4467,117,759 - 67,243,058 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1467,405,110 - 67,426,026 (-)NCBI
Celera463,383,337 - 63,515,499 (-)NCBICelera
Cytogenetic Map4q23NCBI
Braf
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554942,567,238 - 2,712,708 (+)NCBIChiLan1.0ChiLan1.0
BRAF
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26177,509,195 - 177,712,794 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1729,523,822 - 29,723,049 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07132,651,908 - 132,855,422 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17145,124,291 - 145,327,115 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7145,138,510 - 145,327,115 (-)Ensemblpanpan1.1panPan2
Braf
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511814,385,958 - 14,495,443 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365924,737,011 - 4,834,664 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365924,728,371 - 4,833,830 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BRAF
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl188,957,991 - 9,132,553 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1188,957,963 - 9,132,558 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2189,522,257 - 9,636,501 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BRAF
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121109,495,525 - 109,690,261 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660726,137,051 - 6,336,885 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Braf
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476520,773,885 - 20,951,736 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476520,766,368 - 20,951,560 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in BRAF
525 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 3 3 5 8
Low 5 5 19 6 6 6 3 6 7 10 6
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005629550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005629551 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022403735 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022403736 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038452809 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038452810 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038452811 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038452812 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038452813 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038452814 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038452815 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038452816 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038497047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038497048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038497049 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038497050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038497051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038497052 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038559385 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038559386 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038559387 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038559388 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038559389 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038559390 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038623366 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038623367 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038623368 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038623369 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038623370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038623371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038689084 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038689085 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038689086 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038689087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038689088 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038689089 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY545218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY545219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000104 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MN581672 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSCAFT00000006305   ⟹   ENSCAFP00000005841
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl168,222,907 - 8,317,906 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000006306   ⟹   ENSCAFP00000005842
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl168,222,907 - 8,317,906 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000092688   ⟹   ENSCAFP00000064812
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl168,222,907 - 8,317,906 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845055173   ⟹   ENSCAFP00845043390
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl168,065,737 - 8,239,141 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845055177   ⟹   ENSCAFP00845043393
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl168,065,737 - 8,239,141 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845055184   ⟹   ENSCAFP00845043400
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl168,065,737 - 8,239,141 (+)Ensembl
RefSeq Acc Id: XM_038452809   ⟹   XP_038308737
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha168,989,501 - 9,160,850 (+)NCBI
RefSeq Acc Id: XM_038452810   ⟹   XP_038308738
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha168,989,501 - 9,155,826 (+)NCBI
RefSeq Acc Id: XM_038452811   ⟹   XP_038308739
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha168,989,501 - 9,160,850 (+)NCBI
RefSeq Acc Id: XM_038452812   ⟹   XP_038308740
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha168,989,501 - 9,144,914 (+)NCBI
RefSeq Acc Id: XM_038452813   ⟹   XP_038308741
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha168,989,501 - 9,143,944 (+)NCBI
RefSeq Acc Id: XM_038452814   ⟹   XP_038308742
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha169,077,720 - 9,160,850 (+)NCBI
RefSeq Acc Id: XM_038452815   ⟹   XP_038308743
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha168,989,501 - 9,160,850 (+)NCBI
RefSeq Acc Id: XM_038452816   ⟹   XP_038308744
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha168,989,501 - 9,155,826 (+)NCBI
RefSeq Acc Id: XM_038497047   ⟹   XP_038352975
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1168,017,140 - 8,188,930 (+)NCBI
RefSeq Acc Id: XM_038497048   ⟹   XP_038352976
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1168,017,140 - 8,188,930 (+)NCBI
RefSeq Acc Id: XM_038497049   ⟹   XP_038352977
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1168,017,140 - 8,173,018 (+)NCBI
RefSeq Acc Id: XM_038497050   ⟹   XP_038352978
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1168,017,140 - 8,172,049 (+)NCBI
RefSeq Acc Id: XM_038497051   ⟹   XP_038352979
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1168,105,861 - 8,188,930 (+)NCBI
RefSeq Acc Id: XM_038497052   ⟹   XP_038352980
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1168,017,140 - 8,188,930 (+)NCBI
RefSeq Acc Id: XM_038559385   ⟹   XP_038415313
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0167,929,505 - 8,101,841 (+)NCBI
RefSeq Acc Id: XM_038559386   ⟹   XP_038415314
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0167,929,505 - 8,101,841 (+)NCBI
RefSeq Acc Id: XM_038559387   ⟹   XP_038415315
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0167,929,505 - 8,085,895 (+)NCBI
RefSeq Acc Id: XM_038559388   ⟹   XP_038415316
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0167,929,505 - 8,084,926 (+)NCBI
RefSeq Acc Id: XM_038559389   ⟹   XP_038415317
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0168,018,347 - 8,101,841 (+)NCBI
RefSeq Acc Id: XM_038559390   ⟹   XP_038415318
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0167,929,505 - 8,101,841 (+)NCBI
RefSeq Acc Id: XM_038623366   ⟹   XP_038479294
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0167,861,588 - 8,033,660 (+)NCBI
RefSeq Acc Id: XM_038623367   ⟹   XP_038479295
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0167,861,588 - 8,033,660 (+)NCBI
RefSeq Acc Id: XM_038623368   ⟹   XP_038479296
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0167,861,588 - 8,017,730 (+)NCBI
RefSeq Acc Id: XM_038623369   ⟹   XP_038479297
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0167,861,588 - 8,016,761 (+)NCBI
RefSeq Acc Id: XM_038623370   ⟹   XP_038479298
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0167,950,421 - 8,033,660 (+)NCBI
RefSeq Acc Id: XM_038623371   ⟹   XP_038479299
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0167,861,588 - 8,033,660 (+)NCBI
RefSeq Acc Id: XM_038689084   ⟹   XP_038545012
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0168,065,738 - 8,237,942 (+)NCBI
RefSeq Acc Id: XM_038689085   ⟹   XP_038545013
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0168,065,738 - 8,237,942 (+)NCBI
RefSeq Acc Id: XM_038689086   ⟹   XP_038545014
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0168,065,738 - 8,222,010 (+)NCBI
RefSeq Acc Id: XM_038689087   ⟹   XP_038545015
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0168,065,738 - 8,221,041 (+)NCBI
RefSeq Acc Id: XM_038689088   ⟹   XP_038545016
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0168,154,674 - 8,237,942 (+)NCBI
RefSeq Acc Id: XM_038689089   ⟹   XP_038545017
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0168,065,738 - 8,237,942 (+)NCBI
Protein Sequences
Protein RefSeqs XP_038308737 (Get FASTA)   NCBI Sequence Viewer  
  XP_038308738 (Get FASTA)   NCBI Sequence Viewer  
  XP_038308739 (Get FASTA)   NCBI Sequence Viewer  
  XP_038308740 (Get FASTA)   NCBI Sequence Viewer  
  XP_038308741 (Get FASTA)   NCBI Sequence Viewer  
  XP_038308742 (Get FASTA)   NCBI Sequence Viewer  
  XP_038308743 (Get FASTA)   NCBI Sequence Viewer  
  XP_038308744 (Get FASTA)   NCBI Sequence Viewer  
  XP_038352975 (Get FASTA)   NCBI Sequence Viewer  
  XP_038352976 (Get FASTA)   NCBI Sequence Viewer  
  XP_038352977 (Get FASTA)   NCBI Sequence Viewer  
  XP_038352978 (Get FASTA)   NCBI Sequence Viewer  
  XP_038352979 (Get FASTA)   NCBI Sequence Viewer  
  XP_038352980 (Get FASTA)   NCBI Sequence Viewer  
  XP_038415313 (Get FASTA)   NCBI Sequence Viewer  
  XP_038415314 (Get FASTA)   NCBI Sequence Viewer  
  XP_038415315 (Get FASTA)   NCBI Sequence Viewer  
  XP_038415316 (Get FASTA)   NCBI Sequence Viewer  
  XP_038415317 (Get FASTA)   NCBI Sequence Viewer  
  XP_038415318 (Get FASTA)   NCBI Sequence Viewer  
  XP_038479294 (Get FASTA)   NCBI Sequence Viewer  
  XP_038479295 (Get FASTA)   NCBI Sequence Viewer  
  XP_038479296 (Get FASTA)   NCBI Sequence Viewer  
  XP_038479297 (Get FASTA)   NCBI Sequence Viewer  
  XP_038479298 (Get FASTA)   NCBI Sequence Viewer  
  XP_038479299 (Get FASTA)   NCBI Sequence Viewer  
  XP_038545012 (Get FASTA)   NCBI Sequence Viewer  
  XP_038545013 (Get FASTA)   NCBI Sequence Viewer  
  XP_038545014 (Get FASTA)   NCBI Sequence Viewer  
  XP_038545015 (Get FASTA)   NCBI Sequence Viewer  
  XP_038545016 (Get FASTA)   NCBI Sequence Viewer  
  XP_038545017 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAT77155 (Get FASTA)   NCBI Sequence Viewer  
  AAT77156 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCAFP00000005841.4
  ENSCAFP00000005842.5
  ENSCAFP00000064812.2
  ENSCAFP00030010265.1
  ENSCAFP00030010333.1
  ENSCAFP00040012062.1
  ENSCAFP00040012093.1
  ENSCAFP00845043390
  ENSCAFP00845043390.1
  ENSCAFP00845043393
  ENSCAFP00845043393.1
  ENSCAFP00845043400.1
GenBank Protein QHJ68501 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: ENSCAFP00000005841   ⟸   ENSCAFT00000006305
RefSeq Acc Id: ENSCAFP00000005842   ⟸   ENSCAFT00000006306
RefSeq Acc Id: ENSCAFP00000064812   ⟸   ENSCAFT00000092688
RefSeq Acc Id: XP_038352980   ⟸   XM_038497052
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038352975   ⟸   XM_038497047
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038352976   ⟸   XM_038497048
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038352977   ⟸   XM_038497049
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038352978   ⟸   XM_038497050
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038352979   ⟸   XM_038497051
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038479299   ⟸   XM_038623371
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038479294   ⟸   XM_038623366
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038479295   ⟸   XM_038623367
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038479296   ⟸   XM_038623368
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038479297   ⟸   XM_038623369
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038479298   ⟸   XM_038623370
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038545017   ⟸   XM_038689089
- Peptide Label: isoform X6
- UniProtKB: A0A8C0S060 (UniProtKB/TrEMBL),   A0A8I3SCX1 (UniProtKB/TrEMBL),   Q698R1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038545012   ⟸   XM_038689084
- Peptide Label: isoform X1
- UniProtKB: Q698R1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038545013   ⟸   XM_038689085
- Peptide Label: isoform X2
- UniProtKB: A0A6B9SMP2 (UniProtKB/TrEMBL),   Q698R1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038545014   ⟸   XM_038689086
- Peptide Label: isoform X3
- UniProtKB: A0A8C0MIU3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038545015   ⟸   XM_038689087
- Peptide Label: isoform X4
- UniProtKB: A0A8C0MIU3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038545016   ⟸   XM_038689088
- Peptide Label: isoform X5
- UniProtKB: A0A8C0L7C0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038308743   ⟸   XM_038452815
- Peptide Label: isoform X6
- UniProtKB: A0A8C0S060 (UniProtKB/TrEMBL),   A0A8I3SCX1 (UniProtKB/TrEMBL),   Q698R1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038308737   ⟸   XM_038452809
- Peptide Label: isoform X1
- UniProtKB: Q698R1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038308739   ⟸   XM_038452811
- Peptide Label: isoform X2
- UniProtKB: A0A6B9SMP2 (UniProtKB/TrEMBL),   Q698R1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038308744   ⟸   XM_038452816
- Peptide Label: isoform X8
- UniProtKB: Q698R1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038308738   ⟸   XM_038452810
- Peptide Label: isoform X7
- UniProtKB: Q698R1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038308740   ⟸   XM_038452812
- Peptide Label: isoform X3
- UniProtKB: A0A8C0MIU3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038308741   ⟸   XM_038452813
- Peptide Label: isoform X4
- UniProtKB: A0A8C0MIU3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038308742   ⟸   XM_038452814
- Peptide Label: isoform X5
- UniProtKB: A0A8C0L7C0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038415318   ⟸   XM_038559390
- Peptide Label: isoform X6
- UniProtKB: A0A8C0S060 (UniProtKB/TrEMBL),   A0A8I3SCX1 (UniProtKB/TrEMBL),   Q698R1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038415313   ⟸   XM_038559385
- Peptide Label: isoform X1
- UniProtKB: Q698R1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038415314   ⟸   XM_038559386
- Peptide Label: isoform X2
- UniProtKB: A0A6B9SMP2 (UniProtKB/TrEMBL),   Q698R1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038415315   ⟸   XM_038559387
- Peptide Label: isoform X3
- UniProtKB: A0A8C0MIU3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038415316   ⟸   XM_038559388
- Peptide Label: isoform X4
- UniProtKB: A0A8C0MIU3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038415317   ⟸   XM_038559389
- Peptide Label: isoform X5
- UniProtKB: A0A8C0L7C0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845043393   ⟸   ENSCAFT00845055177
RefSeq Acc Id: ENSCAFP00845043390   ⟸   ENSCAFT00845055173
RefSeq Acc Id: ENSCAFP00845043400   ⟸   ENSCAFT00845055184
Protein Domains
Phorbol-ester/DAG-type   Protein kinase   RBD


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000003907 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030006391 UniProtKB/TrEMBL
  ENSCAFG00040007486 UniProtKB/TrEMBL
  ENSCAFG00845031038 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000006305.6 UniProtKB/TrEMBL
  ENSCAFT00000006306.5 UniProtKB/TrEMBL
  ENSCAFT00000092688.2 UniProtKB/TrEMBL
  ENSCAFT00030011725.1 UniProtKB/TrEMBL
  ENSCAFT00030011794.1 UniProtKB/TrEMBL
  ENSCAFT00040013934.1 UniProtKB/TrEMBL
  ENSCAFT00040013975.1 UniProtKB/TrEMBL
  ENSCAFT00845055173 ENTREZGENE
  ENSCAFT00845055173.1 UniProtKB/TrEMBL
  ENSCAFT00845055177 ENTREZGENE
  ENSCAFT00845055177.1 UniProtKB/TrEMBL
  ENSCAFT00845055184.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.60.20 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro C1-like_sf UniProtKB/TrEMBL
  DAG/PE-bd UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  PE/DAG-bd UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  RBD_dom UniProtKB/TrEMBL
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/TrEMBL
NCBI Gene BRAF ENTREZGENE
PANTHER SERINE/THREONINE-PROTEIN KINASE B-RAF UniProtKB/TrEMBL
  SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED UniProtKB/TrEMBL
Pfam C1_1 UniProtKB/TrEMBL
  PK_Tyr_Ser-Thr UniProtKB/TrEMBL
  RBD UniProtKB/TrEMBL
PRINTS DAGPEDOMAIN UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
  RBD UniProtKB/TrEMBL
  ZF_DAG_PE_1 UniProtKB/TrEMBL
  ZF_DAG_PE_2 UniProtKB/TrEMBL
SMART RBD UniProtKB/TrEMBL
  S_TKc UniProtKB/TrEMBL
  SM00109 UniProtKB/TrEMBL
Superfamily-SCOP SSF54236 UniProtKB/TrEMBL
  SSF56112 UniProtKB/TrEMBL
  SSF57889 UniProtKB/TrEMBL
UniProt A0A6B9SMP2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0L7C0 ENTREZGENE
  A0A8C0MIU3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0QQ90_CANLF UniProtKB/TrEMBL
  A0A8C0S060 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3QBG2_CANLF UniProtKB/TrEMBL
  A0A8I3QW85_CANLF UniProtKB/TrEMBL
  A0A8I3SCX1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0N6P0_CANLF UniProtKB/TrEMBL
  A0A8P0PDE0_CANLF UniProtKB/TrEMBL
  Q698R0_CANLF UniProtKB/TrEMBL
  Q698R1 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:38514 ENTREZGENE