MIR144 (microRNA mir-144) - Rat Genome Database

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Gene: MIR144 (microRNA mir-144) Canis lupus familiaris
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Symbol: MIR144
Name: microRNA mir-144
RGD ID: 12229029
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna
RefSeq Status: PROVISIONAL
Previously known as: cfa-mir-144; microRNA 144
RGD Orthologs
Human
Mouse
Rat
Pig
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1943,031,035 - 43,031,094 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl943,031,035 - 43,031,094 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha942,186,177 - 42,186,236 (-)NCBI
ROS_Cfam_1.0943,848,755 - 43,848,814 (-)NCBI
ROS_Cfam_1.0 Ensembl943,848,755 - 43,848,814 (-)Ensembl
UMICH_Zoey_3.1942,632,295 - 42,632,354 (-)NCBI
UNSW_CanFamBas_1.0942,924,318 - 42,924,377 (-)NCBI
UU_Cfam_GSD_1.0943,002,958 - 43,003,017 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:16381832   PMID:18392026  


Genomics

Comparative Map Data
MIR144
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1943,031,035 - 43,031,094 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl943,031,035 - 43,031,094 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha942,186,177 - 42,186,236 (-)NCBI
ROS_Cfam_1.0943,848,755 - 43,848,814 (-)NCBI
ROS_Cfam_1.0 Ensembl943,848,755 - 43,848,814 (-)Ensembl
UMICH_Zoey_3.1942,632,295 - 42,632,354 (-)NCBI
UNSW_CanFamBas_1.0942,924,318 - 42,924,377 (-)NCBI
UU_Cfam_GSD_1.0943,002,958 - 43,003,017 (-)NCBI
MIR144
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381728,861,533 - 28,861,618 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1728,861,533 - 28,861,618 (-)EnsemblGRCh38hg38GRCh38
GRCh371727,188,551 - 27,188,636 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361724,212,676 - 24,212,761 (-)NCBINCBI36hg18NCBI36
Celera1724,047,975 - 24,048,060 (-)NCBI
Cytogenetic Map17q11.2NCBI
HuRef1723,396,841 - 23,396,926 (-)NCBIHuRef
CHM1_11727,251,065 - 27,251,150 (-)NCBICHM1_1
T2T-CHM13v2.01729,804,306 - 29,804,391 (-)NCBI
Mir144
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391177,963,831 - 77,963,896 (+)NCBIGRCm39mm39
GRCm39 Ensembl1177,963,831 - 77,963,896 (+)Ensembl
GRCm381178,073,005 - 78,073,070 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1178,073,005 - 78,073,070 (+)EnsemblGRCm38mm10GRCm38
MGSCv371177,886,507 - 77,886,572 (+)NCBIGRCm37mm9NCBIm37
Celera1185,572,607 - 85,572,672 (+)NCBICelera
Cytogenetic Map11B5NCBI
Mir144
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21062,961,348 - 62,961,430 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1062,961,348 - 62,961,430 (+)Ensembl
Rnor_6.01065,291,365 - 65,291,447 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1065,291,365 - 65,291,447 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01066,340,681 - 66,340,763 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1061,939,438 - 61,939,520 (+)NCBICelera
Cytogenetic Map10q25NCBI
MIR144
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1245,088,959 - 45,089,035 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11245,088,958 - 45,089,033 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21247,176,953 - 47,177,028 (+)NCBISscrofa10.2Sscrofa10.2susScr3


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system
High
Medium
Low 1 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000032684
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl943,031,035 - 43,031,094 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845016048
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl943,848,755 - 43,848,814 (-)Ensembl
RefSeq Acc Id: NR_049384
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1943,031,035 - 43,031,094 (-)NCBI
Dog10K_Boxer_Tasha942,186,177 - 42,186,236 (-)NCBI
ROS_Cfam_1.0943,848,755 - 43,848,814 (-)NCBI
UMICH_Zoey_3.1942,632,295 - 42,632,354 (-)NCBI
UNSW_CanFamBas_1.0942,924,318 - 42,924,377 (-)NCBI
UU_Cfam_GSD_1.0943,002,958 - 43,003,017 (-)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000020577 Ensembl
  ENSCAFG00845009106 Ensembl, ENTREZGENE
Ensembl Transcript ENSCAFT00845016048 ENTREZGENE
miRBase MI0008158 ENTREZGENE
NCBI Gene MIR144 ENTREZGENE
RNAcentral URS000041D05E RNACentral
  URS00007E4E3C RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-02 MIR144  microRNA mir-144    microRNA 144  Symbol and/or name change 5135510 APPROVED