SLC3A2 (solute carrier family 3 member 2) - Rat Genome Database

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Gene: SLC3A2 (solute carrier family 3 member 2) Canis lupus familiaris
Analyze
Symbol: SLC3A2
Name: solute carrier family 3 member 2
RGD ID: 12310193
Description: ENCODES a protein that exhibits double-stranded RNA binding (ortholog); neutral amino acid transmembrane transporter activity (ortholog); INVOLVED IN leucine import across plasma membrane (ortholog); leucine transport (ortholog); neutral amino acid transport (ortholog); PARTICIPATES IN amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; bumetanide pharmacodynamics pathway; ASSOCIATED WITH familial temporal lobe epilepsy 8 (ortholog); intellectual disability (ortholog); Lung Neoplasms (ortholog); FOUND IN apical plasma membrane (ortholog); basal plasma membrane (ortholog); basolateral plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4F2 cell-surface antigen heavy chain; 4F2hc; solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11853,810,468 - 53,819,021 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1853,810,398 - 53,819,021 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1852,416,355 - 52,424,896 (-)NCBI
ROS_Cfam_1.01854,862,432 - 54,870,971 (-)NCBI
UMICH_Zoey_3.11853,959,818 - 53,968,341 (-)NCBI
UNSW_CanFamBas_1.01853,533,954 - 53,542,486 (-)NCBI
UU_Cfam_GSD_1.01854,325,863 - 54,334,403 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References

Genomics

Comparative Map Data
SLC3A2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11853,810,468 - 53,819,021 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1853,810,398 - 53,819,021 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1852,416,355 - 52,424,896 (-)NCBI
ROS_Cfam_1.01854,862,432 - 54,870,971 (-)NCBI
UMICH_Zoey_3.11853,959,818 - 53,968,341 (-)NCBI
UNSW_CanFamBas_1.01853,533,954 - 53,542,486 (-)NCBI
UU_Cfam_GSD_1.01854,325,863 - 54,334,403 (-)NCBI
SLC3A2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1162,856,004 - 62,888,880 (+)EnsemblGRCh38hg38GRCh38
GRCh381162,856,109 - 62,888,860 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371162,623,581 - 62,656,332 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361162,380,094 - 62,412,929 (+)NCBINCBI36hg18NCBI36
Build 341162,380,149 - 62,412,840NCBI
Celera1159,946,914 - 59,979,926 (+)NCBI
Cytogenetic Map11q12.3NCBI
HuRef1158,952,521 - 58,985,401 (+)NCBIHuRef
CHM1_11162,506,504 - 62,539,366 (+)NCBICHM1_1
Slc3a2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39198,684,246 - 8,700,733 (-)NCBIGRCm39mm39
GRCm39 Ensembl198,684,246 - 8,700,733 (-)Ensembl
GRCm38198,706,882 - 8,723,369 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl198,706,882 - 8,723,369 (-)EnsemblGRCm38mm10GRCm38
MGSCv37198,781,372 - 8,797,859 (-)NCBIGRCm37mm9NCBIm37
MGSCv36198,773,927 - 8,780,919 (-)NCBImm8
Celera198,465,148 - 8,481,790 (-)NCBICelera
Cytogenetic Map19ANCBI
cM Map195.44NCBI
Slc3a2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21205,604,468 - 205,618,931 (-)NCBI
Rnor_6.0 Ensembl1224,906,554 - 224,921,092 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01224,906,566 - 224,921,029 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01231,843,822 - 231,858,285 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41211,375,889 - 211,390,313 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11211,534,318 - 211,548,743 (-)NCBI
Celera1203,117,365 - 203,131,828 (-)NCBICelera
Cytogenetic Map1q43NCBI
Slc3a2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955599376,245 - 391,311 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955599376,133 - 391,434 (-)NCBIChiLan1.0ChiLan1.0
SLC3A2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11161,565,664 - 61,594,579 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1161,565,680 - 61,594,579 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01158,212,395 - 58,241,686 (+)NCBIMhudiblu_PPA_v0panPan3
Slc3a2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494710,311,055 - 10,327,851 (-)NCBI
SpeTri2.0NW_004936581424,801 - 441,592 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC3A2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl28,892,089 - 8,919,072 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.128,892,071 - 8,919,070 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.228,245,279 - 8,273,049 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLC3A2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1111,011,351 - 11,050,494 (-)NCBI
ChlSab1.1 Ensembl111,008,120 - 11,050,298 (-)Ensembl
Vero_WHO_p1.0NW_023666038108,363,791 - 108,393,242 (-)NCBI
Slc3a2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249261,301,866 - 1,314,598 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 5 22 6 6 6 6 6 12 8 10 6
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000024598   ⟹   ENSCAFP00000022829
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1853,810,398 - 53,819,021 (-)Ensembl
RefSeq Acc Id: NM_001314120   ⟹   NP_001301049
RefSeq Status: VALIDATED
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11853,810,468 - 53,819,021 (-)NCBI
Dog10K_Boxer_Tasha1852,416,355 - 52,424,896 (-)NCBI
ROS_Cfam_1.01854,862,432 - 54,870,971 (-)NCBI
UMICH_Zoey_3.11853,959,818 - 53,968,341 (-)NCBI
UNSW_CanFamBas_1.01853,533,954 - 53,542,486 (-)NCBI
UU_Cfam_GSD_1.01854,325,863 - 54,334,403 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001301049 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAO65809 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001301049   ⟸   NM_001314120
- Sequence:
RefSeq Acc Id: ENSCAFP00000022829   ⟸   ENSCAFT00000024598
Protein Domains
Aamy

Promoters
RGD ID:13686640
Promoter ID:EPDNEW_C4708
Type:initiation region
Name:SLC3A2_1
Description:Canis lupus familiaris solute carrier family 3 member 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11853,818,963 - 53,819,023EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000015495 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00000022829 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000024598 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.1180 UniProtKB/TrEMBL
InterPro Glyco_hydro_13_cat_dom UniProtKB/TrEMBL
  Glyco_hydro_b UniProtKB/TrEMBL
  Glycoside_hydrolase_SF UniProtKB/TrEMBL
  SLC3A2 UniProtKB/TrEMBL
  SLC3A2_N UniProtKB/TrEMBL
KEGG Report cfa:483777 UniProtKB/TrEMBL
NCBI Gene SLC3A2 ENTREZGENE
PANTHER PTHR46673 UniProtKB/TrEMBL
Pfam Alpha-amylase UniProtKB/TrEMBL
  SLC3A2_N UniProtKB/TrEMBL
SMART Aamy UniProtKB/TrEMBL
Superfamily-SCOP SSF51445 UniProtKB/TrEMBL
UniProt F1PRC5_CANLF UniProtKB/TrEMBL
  X5IHJ5_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:46410 ENTREZGENE