DNMT1 (DNA methyltransferase 1) - Rat Genome Database

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Gene: DNMT1 (DNA methyltransferase 1) Canis lupus familiaris
Analyze
Symbol: DNMT1
Name: DNA methyltransferase 1
RGD ID: 12303750
Description: ENCODES a protein that exhibits DNA (cytosine-5-)-methyltransferase activity (ortholog); histone deacetylase binding (ortholog); nuclear estrogen receptor binding (ortholog); INVOLVED IN cellular response to amino acid stimulus (ortholog); cellular response to bisphenol A (ortholog); cellular response to lead ion (ortholog); PARTICIPATES IN DNA modification pathway; glycine N-methyltransferase deficiency pathway; homocysteine metabolic pathway; ASSOCIATED WITH acute myeloid leukemia (ortholog); adenocarcinoma (ortholog); alopecia areata (ortholog); FOUND IN mitochondrion (ortholog); nucleus (ortholog); protein-containing complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: DNA (cytosine-5)-methyltransferase 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12050,872,213 - 50,928,352 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2050,879,527 - 50,928,029 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2050,741,748 - 50,797,884 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02051,393,895 - 51,450,128 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2051,401,720 - 51,450,127 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12050,599,735 - 50,657,798 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02051,028,945 - 51,085,072 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02051,269,676 - 51,325,956 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acute myeloid leukemia  (ISO)
adenocarcinoma  (ISO)
alopecia areata  (ISO)
anxiety disorder  (ISO)
asthma  (ISO)
Ataxia  (ISO)
autism spectrum disorder  (ISO)
autoimmune disease  (ISO)
autosomal dominant cerebellar ataxia, deafness and narcolepsy  (ISO)
Beckwith-Wiedemann syndrome  (ISO)
Binge Drinking  (ISO)
Brain Injuries  (ISO)
Breast Neoplasms  (ISO)
bronchiolo-alveolar adenocarcinoma  (ISO)
Carcinogenesis  (ISO)
carcinoma  (ISO)
cardiomyopathy  (ISO)
cerebellar ataxia  (ISO)
Charcot-Marie-Tooth disease  (ISO)
choline deficiency disease  (ISO)
choreatic disease  (ISO)
chronic myeloid leukemia  (ISO)
clear cell renal cell carcinoma  (ISO)
Colonic Neoplasms  (ISO)
Colorectal Neoplasms  (ISO)
congenital heart disease  (ISO)
congestive heart failure  (ISO)
dementia  (ISO)
Endometrial Neoplasms  (ISO)
Endometrioid Carcinomas  (ISO)
endometriosis  (ISO)
endometriosis of uterus  (ISO)
Experimental Arthritis  (ISO)
familial hypercholesterolemia  (ISO)
fetal alcohol spectrum disorder  (ISO)
Fetal Growth Retardation  (ISO)
genetic disease  (ISO)
Graves' disease  (ISO)
Hearing Loss  (ISO)
hepatocellular carcinoma  (ISO)
hereditary sensory neuropathy  (ISO)
hereditary sensory neuropathy type 1E  (ISO)
hypertrophic cardiomyopathy  (ISO)
immunodeficiency 35  (ISO)
liver cirrhosis  (ISO)
lung cancer  (ISO)
lung carcinoma  (ISO)
lung non-small cell carcinoma  (ISO)
medulloblastoma  (ISO)
metabolic dysfunction and alcohol associated liver disease  (ISO)
middle cerebral artery infarction  (ISO)
mucoepidermoid carcinoma  (ISO)
myelodysplastic syndrome  (ISO)
Neoplasm Invasiveness  (ISO)
Oral Lichen Planus  (ISO)
Ovarian Neoplasms  (ISO)
pancreatic ductal carcinoma  (ISO)
Pancreatic Intraepithelial Neoplasia  (ISO)
Peritoneal Fibrosis  (ISO)
Pituitary Stalk Interruption Syndrome  (ISO)
prostate adenocarcinoma  (ISO)
prostate cancer  (ISO)
prostate carcinoma in situ  (ISO)
Prostatic Neoplasms  (ISO)
rheumatoid arthritis  (ISO)
schizophrenia  (ISO)
sleep disorder  (ISO)
spastic ataxia  (ISO)
Spastic Paraparesis  (ISO)
Stomach Neoplasms  (ISO)
systemic lupus erythematosus  (ISO)
type 2 diabetes mellitus  (ISO)
urinary bladder cancer  (ISO)
Uterine Cervical Neoplasms  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
cellular response to amino acid stimulus  (IEA,ISO)
cellular response to bisphenol A  (IEA,ISO)
cellular response to lead ion  (ISO)
cellular response to nerve growth factor stimulus  (ISO)
cellular response to platelet-derived growth factor stimulus  (ISO)
cellular response to transforming growth factor beta stimulus  (ISO)
chromosomal DNA methylation maintenance following DNA replication  (IEA,ISO)
DNA methylation-dependent constitutive heterochromatin formation  (IEA)
DNA-templated transcription  (IEA,ISO)
epigenetic programming of gene expression  (IEA,ISO)
methylation  (IEA)
negative regulation of DNA-templated transcription  (IEA,ISO)
negative regulation of gene expression  (IEA,ISO)
negative regulation of gene expression via chromosomal CpG island methylation  (IBA,IEA,ISO)
negative regulation of transcription by RNA polymerase II  (IEA,ISO)
negative regulation of vascular associated smooth muscle cell apoptotic process  (IEA)
negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching  (IEA)
neuron differentiation  (ISO)
positive regulation of gene expression  (IEA)
positive regulation of vascular associated smooth muscle cell proliferation  (IEA)
regulation of cell population proliferation  (IEA,ISO)
regulation of gene expression  (IEA,ISO)
response to activity  (ISO)
response to alcohol  (ISO)
response to bisphenol A  (ISO)
response to caffeine  (ISO)
response to estradiol  (ISO)
response to ethanol  (ISO)
response to ionizing radiation  (ISO)
response to lead ion  (ISO)
response to lipopolysaccharide  (ISO)
response to nutrient levels  (ISO)
response to testosterone  (ISO)
response to toxic substance  (ISO)
response to vitamin A  (ISO)
response to xenobiotic stimulus  (ISO)

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:22609058   PMID:30032202  


Genomics

Comparative Map Data
DNMT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12050,872,213 - 50,928,352 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2050,879,527 - 50,928,029 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2050,741,748 - 50,797,884 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02051,393,895 - 51,450,128 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2051,401,720 - 51,450,127 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12050,599,735 - 50,657,798 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02051,028,945 - 51,085,072 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02051,269,676 - 51,325,956 (+)NCBIUU_Cfam_GSD_1.0
DNMT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381910,133,346 - 10,194,953 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1910,133,342 - 10,231,286 (-)EnsemblGRCh38hg38GRCh38
GRCh371910,244,022 - 10,305,629 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361910,105,022 - 10,166,811 (-)NCBINCBI36Build 36hg18NCBI36
Build 341910,105,022 - 10,166,811NCBI
Celera1910,139,454 - 10,201,147 (-)NCBICelera
Cytogenetic Map19p13.2NCBI
HuRef199,824,670 - 9,886,268 (-)NCBIHuRef
CHM1_11910,244,307 - 10,306,021 (-)NCBICHM1_1
T2T-CHM13v2.01910,259,569 - 10,321,116 (-)NCBIT2T-CHM13v2.0
Dnmt1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39920,818,501 - 20,871,084 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl920,818,505 - 20,871,184 (-)EnsemblGRCm39 Ensembl
GRCm38920,907,206 - 20,959,888 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl920,907,209 - 20,959,888 (-)EnsemblGRCm38mm10GRCm38
MGSCv37920,711,653 - 20,757,317 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36920,657,611 - 20,703,267 (-)NCBIMGSCv36mm8
Celera918,175,907 - 18,221,569 (-)NCBICelera
Cytogenetic Map9A3NCBI
cM Map97.66NCBI
Dnmt1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8827,716,797 - 27,763,405 (-)NCBIGRCr8
mRatBN7.2819,440,611 - 19,486,659 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl819,440,611 - 19,486,659 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx823,459,969 - 23,505,932 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0821,757,816 - 21,803,779 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0819,670,294 - 19,716,334 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0821,922,515 - 21,968,495 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl821,922,515 - 21,968,495 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0821,978,830 - 22,024,656 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4819,926,995 - 19,973,256 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1819,927,666 - 19,973,220 (-)NCBI
Celera820,835,612 - 20,881,380 (-)NCBICelera
Cytogenetic Map8q13NCBI
Dnmt1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554951,465,480 - 1,505,462 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554951,465,529 - 1,505,379 (-)NCBIChiLan1.0ChiLan1.0
DNMT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22015,048,374 - 15,112,823 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11914,048,694 - 14,110,457 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0199,681,847 - 9,745,334 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11910,342,478 - 10,390,397 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1910,342,478 - 10,406,972 (-)Ensemblpanpan1.1panPan2
Dnmt1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118209,789,213 - 209,834,531 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936659520,493 - 565,416 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936659520,181 - 565,496 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DNMT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl268,981,566 - 69,029,844 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1268,981,564 - 69,040,364 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2269,309,511 - 69,357,838 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DNMT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.169,199,006 - 9,263,890 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl69,199,003 - 9,263,607 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607410,795,260 - 10,857,063 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dnmt1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248282,315,251 - 2,358,711 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248282,316,042 - 2,358,866 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in DNMT1
563 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_022407066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022407067 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022407068 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038428672 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038428673 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038428674 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038428675 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038455410 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038504315 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038504316 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038504317 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038504318 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038504319 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038567347 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038567348 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038567349 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038567350 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038631495 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038631496 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038631497 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038631498 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038631499 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_533919 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000058 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000291 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCAFT00000028398   ⟹   ENSCAFP00000026412
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2050,879,527 - 50,928,029 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845032287   ⟹   ENSCAFP00845025238
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2051,401,720 - 51,450,127 (+)Ensembl
RefSeq Acc Id: XM_022407066   ⟹   XP_022262774
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12050,880,007 - 50,928,352 (+)NCBI
Dog10K_Boxer_Tasha2050,749,539 - 50,797,884 (+)NCBI
Sequence:
RefSeq Acc Id: XM_022407067   ⟹   XP_022262775
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12050,880,358 - 50,928,352 (+)NCBI
Dog10K_Boxer_Tasha2050,749,890 - 50,797,884 (+)NCBI
Sequence:
RefSeq Acc Id: XM_022407068   ⟹   XP_022262776
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12050,872,213 - 50,928,352 (+)NCBI
Dog10K_Boxer_Tasha2050,741,748 - 50,797,884 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038428672   ⟹   XP_038284600
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02051,401,677 - 51,450,128 (+)NCBI
RefSeq Acc Id: XM_038428673   ⟹   XP_038284601
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02051,402,028 - 51,450,128 (+)NCBI
RefSeq Acc Id: XM_038428674   ⟹   XP_038284602
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02051,393,895 - 51,450,128 (+)NCBI
RefSeq Acc Id: XM_038428675   ⟹   XP_038284603
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02051,417,259 - 51,450,128 (+)NCBI
RefSeq Acc Id: XM_038455410   ⟹   XP_038311338
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha2050,765,109 - 50,797,884 (+)NCBI
RefSeq Acc Id: XM_038504315   ⟹   XP_038360243
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12050,607,526 - 50,657,798 (+)NCBI
RefSeq Acc Id: XM_038504316   ⟹   XP_038360244
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12050,607,526 - 50,657,798 (+)NCBI
RefSeq Acc Id: XM_038504317   ⟹   XP_038360245
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12050,607,877 - 50,657,798 (+)NCBI
RefSeq Acc Id: XM_038504318   ⟹   XP_038360246
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12050,599,735 - 50,657,798 (+)NCBI
RefSeq Acc Id: XM_038504319   ⟹   XP_038360247
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12050,623,070 - 50,657,798 (+)NCBI
RefSeq Acc Id: XM_038567347   ⟹   XP_038423275
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02051,277,476 - 51,325,956 (+)NCBI
RefSeq Acc Id: XM_038567348   ⟹   XP_038423276
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02051,277,827 - 51,325,956 (+)NCBI
RefSeq Acc Id: XM_038567349   ⟹   XP_038423277
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02051,269,676 - 51,325,956 (+)NCBI
RefSeq Acc Id: XM_038567350   ⟹   XP_038423278
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02051,293,292 - 51,325,956 (+)NCBI
RefSeq Acc Id: XM_038631495   ⟹   XP_038487423
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02051,036,735 - 51,085,072 (+)NCBI
RefSeq Acc Id: XM_038631496   ⟹   XP_038487424
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02051,036,735 - 51,085,072 (+)NCBI
RefSeq Acc Id: XM_038631497   ⟹   XP_038487425
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02051,037,086 - 51,085,072 (+)NCBI
RefSeq Acc Id: XM_038631498   ⟹   XP_038487426
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02051,028,945 - 51,085,072 (+)NCBI
RefSeq Acc Id: XM_038631499   ⟹   XP_038487427
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02051,052,301 - 51,085,072 (+)NCBI
RefSeq Acc Id: XM_533919   ⟹   XP_533919
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12050,880,007 - 50,928,352 (+)NCBI
Dog10K_Boxer_Tasha2050,749,539 - 50,797,884 (+)NCBI
Sequence:
RefSeq Acc Id: XP_533919   ⟸   XM_533919
- Peptide Label: isoform X3
- UniProtKB: A0A8I3NUZ2 (UniProtKB/TrEMBL),   A0A8P0SM11 (UniProtKB/TrEMBL),   A0A8C0RQ92 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022262776   ⟸   XM_022407068
- Peptide Label: isoform X13
- UniProtKB: A0A8C0RQ92 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022262774   ⟸   XM_022407066
- Peptide Label: isoform X11
- UniProtKB: A0A8C0RQ92 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022262775   ⟸   XM_022407067
- Peptide Label: isoform X12
- UniProtKB: A0A8C0RQ92 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000026412   ⟸   ENSCAFT00000028398
RefSeq Acc Id: XP_038360246   ⟸   XM_038504318
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038360243   ⟸   XM_038504315
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038360244   ⟸   XM_038504316
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038360245   ⟸   XM_038504317
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038360247   ⟸   XM_038504319
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038487426   ⟸   XM_038631498
- Peptide Label: isoform X10
RefSeq Acc Id: XP_038487423   ⟸   XM_038631495
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038487424   ⟸   XM_038631496
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038487425   ⟸   XM_038631497
- Peptide Label: isoform X9
RefSeq Acc Id: XP_038487427   ⟸   XM_038631499
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038284602   ⟸   XM_038428674
- Peptide Label: isoform X2
- UniProtKB: A0A8C0RQ92 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038284600   ⟸   XM_038428672
- Peptide Label: isoform X3
- UniProtKB: A0A8I3NUZ2 (UniProtKB/TrEMBL),   A0A8P0SM11 (UniProtKB/TrEMBL),   A0A8C0RQ92 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038284601   ⟸   XM_038428673
- Peptide Label: isoform X1
- UniProtKB: A0A8C0RQ92 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038284603   ⟸   XM_038428675
- Peptide Label: isoform X4
- UniProtKB: A0A8C0RQ92 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038311338   ⟸   XM_038455410
- Peptide Label: isoform X4
- UniProtKB: A0A8C0RQ92 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038423277   ⟸   XM_038567349
- Peptide Label: isoform X2
- UniProtKB: A0A8C0RQ92 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038423275   ⟸   XM_038567347
- Peptide Label: isoform X3
- UniProtKB: A0A8C0RQ92 (UniProtKB/TrEMBL),   A0A8I3NUZ2 (UniProtKB/TrEMBL),   A0A8P0SM11 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038423276   ⟸   XM_038567348
- Peptide Label: isoform X1
- UniProtKB: A0A8C0RQ92 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038423278   ⟸   XM_038567350
- Peptide Label: isoform X4
- UniProtKB: A0A8C0RQ92 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845025238   ⟸   ENSCAFT00845032287
Protein Domains
BAH   CXXC-type   DMAP1-binding

Promoters
RGD ID:13687047
Promoter ID:EPDNEW_C5112
Type:multiple initiation site
Name:DNMT1_1
Description:DNA methyltransferase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_C5111  
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12050,880,032 - 50,880,092EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000017892 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030021211 UniProtKB/TrEMBL
  ENSCAFG00040021646 UniProtKB/TrEMBL
  ENSCAFG00845018246 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000028398.5 UniProtKB/TrEMBL
  ENSCAFT00030038943.1 UniProtKB/TrEMBL
  ENSCAFT00040040184.1 UniProtKB/TrEMBL
  ENSCAFT00845032287 ENTREZGENE
  ENSCAFT00845032287.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.2230 UniProtKB/TrEMBL
  2.30.30.490 UniProtKB/TrEMBL
  3.40.50.150 UniProtKB/TrEMBL
  DNA Methylase, subunit A, domain 2 UniProtKB/TrEMBL
InterPro BAH_dom UniProtKB/TrEMBL
  BAH_sf UniProtKB/TrEMBL
  C5-Methyltransferase UniProtKB/TrEMBL
  C5_DNA_meth_AS UniProtKB/TrEMBL
  C5_MeTfrase UniProtKB/TrEMBL
  C5_meth_CS UniProtKB/TrEMBL
  Cytosine_MeTrfase1_RFD UniProtKB/TrEMBL
  DMAP1-bd UniProtKB/TrEMBL
  DNMT1-like UniProtKB/TrEMBL
  SAM-dependent_MTases UniProtKB/TrEMBL
  Znf_CXXC UniProtKB/TrEMBL
NCBI Gene DNMT1 ENTREZGENE
PANTHER CYTOSINE-SPECIFIC METHYLTRANSFERASE UniProtKB/TrEMBL
  DNA (CYTOSINE-5)-METHYLTRANSFERASE 1 UniProtKB/TrEMBL
Pfam BAH UniProtKB/TrEMBL
  DMAP_binding UniProtKB/TrEMBL
  DNA_methylase UniProtKB/TrEMBL
  DNMT1-RFD UniProtKB/TrEMBL
  zf-CXXC UniProtKB/TrEMBL
PIRSF DNMT1 UniProtKB/TrEMBL
PRINTS C5METTRFRASE UniProtKB/TrEMBL
PROSITE BAH UniProtKB/TrEMBL
  C5_MTASE_1 UniProtKB/TrEMBL
  C5_MTASE_2 UniProtKB/TrEMBL
  DMAP1_BIND UniProtKB/TrEMBL
  SAM_MT_C5 UniProtKB/TrEMBL
  ZF_CXXC UniProtKB/TrEMBL
SMART BAH UniProtKB/TrEMBL
  DMAP_binding UniProtKB/TrEMBL
Superfamily-SCOP SSF53335 UniProtKB/TrEMBL
UniProt A0A8C0RQ92 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NUZ2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0SM11 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:108242 ENTREZGENE