PCBD1 (pterin-4 alpha-carbinolamine dehydratase 1) - Rat Genome Database

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Gene: PCBD1 (pterin-4 alpha-carbinolamine dehydratase 1) Canis lupus familiaris
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Symbol: PCBD1
Name: pterin-4 alpha-carbinolamine dehydratase 1
RGD ID: 12291612
Description: ENCODES a protein that exhibits transcription coactivator activity (ortholog); INVOLVED IN L-phenylalanine metabolic process (ortholog); positive regulation of transcription, DNA-templated (ortholog); regulation of protein binding (ortholog); ASSOCIATED WITH Animal Disease Models (ortholog); Hyperphenylalaninemia with Primapterinuria (ortholog); lung adenocarcinoma (ortholog); FOUND IN nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1); pterin-4-alpha-carbinolamine dehydratase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1421,719,863 - 21,723,493 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl421,719,863 - 21,721,574 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha421,854,056 - 21,858,488 (-)NCBI
ROS_Cfam_1.0421,997,912 - 22,002,345 (-)NCBI
UMICH_Zoey_3.1421,893,535 - 21,897,967 (-)NCBI
UNSW_CanFamBas_1.0422,098,728 - 22,103,182 (-)NCBI
UU_Cfam_GSD_1.0422,451,020 - 22,455,453 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (IEA)
nucleoplasm  (IEA)
nucleus  (ISO)

References

Genomics

Comparative Map Data
PCBD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1421,719,863 - 21,723,493 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl421,719,863 - 21,721,574 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha421,854,056 - 21,858,488 (-)NCBI
ROS_Cfam_1.0421,997,912 - 22,002,345 (-)NCBI
UMICH_Zoey_3.1421,893,535 - 21,897,967 (-)NCBI
UNSW_CanFamBas_1.0422,098,728 - 22,103,182 (-)NCBI
UU_Cfam_GSD_1.0422,451,020 - 22,455,453 (-)NCBI
PCBD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1070,882,280 - 70,888,565 (-)EnsemblGRCh38hg38GRCh38
GRCh381070,882,280 - 70,888,565 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371072,642,037 - 72,648,322 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361072,313,273 - 72,318,547 (-)NCBINCBI36hg18NCBI36
Celera1065,925,552 - 65,930,826 (-)NCBI
Cytogenetic Map10q22.1NCBI
HuRef1066,637,269 - 66,642,544 (-)NCBIHuRef
CHM1_11072,926,052 - 72,931,326 (-)NCBICHM1_1
Pcbd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391060,925,110 - 60,930,108 (+)NCBIGRCm39mm39
GRCm39 Ensembl1060,925,110 - 60,930,103 (+)Ensembl
GRCm381061,089,331 - 61,094,329 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1061,089,331 - 61,094,324 (+)EnsemblGRCm38mm10GRCm38
MGSCv371060,552,091 - 60,557,077 (+)NCBIGRCm37mm9NCBIm37
MGSCv361060,484,716 - 60,489,676 (+)NCBImm8
Celera1062,189,905 - 62,194,954 (+)NCBICelera
Cytogenetic Map10B4NCBI
cM Map1032.14NCBI
Pcbd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22029,037,545 - 29,044,322 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl2028,953,864 - 29,044,292 (+)Ensembl
mRatBN7.2 Ensembl2028,953,864 - 29,044,321 (+)Ensembl
Rnor_6.02030,689,690 - 30,696,465 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2030,690,810 - 30,696,476 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02032,484,965 - 32,491,740 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42028,448,703 - 28,454,184 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12028,462,435 - 28,467,964 (+)NCBI
Celera2030,472,263 - 30,477,776 (+)NCBICelera
Cytogenetic Map20q11NCBI
Pcbd1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543720,482,589 - 20,488,249 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543720,482,589 - 20,487,337 (+)NCBIChiLan1.0ChiLan1.0
PCBD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11069,877,545 - 69,884,030 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1069,878,773 - 69,881,174 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01067,353,903 - 67,359,073 (-)NCBIMhudiblu_PPA_v0panPan3
Pcbd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721359,351,220 - 59,355,096 (+)NCBI
SpeTri2.0NW_0049365217,843,945 - 7,847,827 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PCBD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1473,772,835 - 73,807,281 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11473,769,339 - 73,807,278 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21479,648,886 - 79,655,375 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PCBD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1960,417,301 - 60,422,313 (+)NCBIChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604821,141,594 - 21,146,607 (+)NCBIVero_WHO_p1.0
Pcbd1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247544,893,868 - 4,898,410 (-)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 5 22 6 6 6 6 1 12 10 6
Low 5 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000022390   ⟹   ENSCAFP00000020792
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl421,719,863 - 21,721,574 (-)Ensembl
RefSeq Acc Id: XM_005618986   ⟹   XP_005619043
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1421,719,863 - 21,723,493 (-)NCBI
Dog10K_Boxer_Tasha421,854,056 - 21,857,691 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038473187   ⟹   XP_038329115
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1421,893,535 - 21,897,169 (-)NCBI
RefSeq Acc Id: XM_038473188   ⟹   XP_038329116
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1421,893,535 - 21,897,967 (-)NCBI
RefSeq Acc Id: XM_038490898   ⟹   XP_038346826
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha421,854,056 - 21,858,488 (-)NCBI
RefSeq Acc Id: XM_038534248   ⟹   XP_038390176
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0422,451,020 - 22,454,655 (-)NCBI
RefSeq Acc Id: XM_038534249   ⟹   XP_038390177
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0422,451,020 - 22,455,453 (-)NCBI
RefSeq Acc Id: XM_038598564   ⟹   XP_038454492
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0422,098,728 - 22,102,353 (-)NCBI
RefSeq Acc Id: XM_038598565   ⟹   XP_038454493
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0422,098,728 - 22,103,182 (-)NCBI
RefSeq Acc Id: XM_038662834   ⟹   XP_038518762
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0421,997,912 - 22,001,547 (-)NCBI
RefSeq Acc Id: XM_038662835   ⟹   XP_038518763
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0421,997,912 - 22,002,345 (-)NCBI
Reference Sequences
RefSeq Acc Id: XP_005619043   ⟸   XM_005618986
- Peptide Label: isoform X1
- UniProtKB: F1PU84 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000020792   ⟸   ENSCAFT00000022390
RefSeq Acc Id: XP_038329116   ⟸   XM_038473188
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038329115   ⟸   XM_038473187
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038454493   ⟸   XM_038598565
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038454492   ⟸   XM_038598564
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038518763   ⟸   XM_038662835
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038518762   ⟸   XM_038662834
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038346826   ⟸   XM_038490898
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038390177   ⟸   XM_038534249
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038390176   ⟸   XM_038534248
- Peptide Label: isoform X1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000014104 Ensembl
NCBI Gene PCBD1 ENTREZGENE
UniProt F1PU84 ENTREZGENE
VGNC ID VGNC:44291 ENTREZGENE