PLCG1 (phospholipase C gamma 1) - Rat Genome Database

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Gene: PLCG1 (phospholipase C gamma 1) Canis lupus familiaris
Analyze
Symbol: PLCG1
Name: phospholipase C gamma 1
RGD ID: 12206121
Description: ENCODES a protein that exhibits calcium-dependent phospholipase C activity (ortholog); glutamate receptor binding (ortholog); insulin receptor binding (ortholog); INVOLVED IN calcium ion transport (ortholog); calcium-mediated signaling (ortholog); cell migration (ortholog); PARTICIPATES IN E-cadherin signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; epidermal growth factor/neuregulin signaling pathway; ASSOCIATED WITH adult T-cell leukemia (ortholog); Alzheimer's disease (ortholog); angiosarcoma (ortholog); FOUND IN cell projection (ortholog); cell-cell junction (ortholog); clathrin-coated vesicle (ortholog); INTERACTS WITH 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine; 1-stearoyl-2-arachidonoylphosphatidic acid; dihexadecanoyl phosphatidic acid
Type: protein-coding
RefSeq Status: MODEL
Also known as: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12429,198,536 - 29,213,899 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2429,198,556 - 29,214,714 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2428,823,106 - 28,859,401 (+)NCBI
ROS_Cfam_1.02429,883,241 - 29,919,530 (+)NCBI
UMICH_Zoey_3.12429,152,120 - 29,188,420 (+)NCBI
UNSW_CanFamBas_1.02429,256,001 - 29,292,271 (+)NCBI
UU_Cfam_GSD_1.02429,752,157 - 29,788,483 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

Genomics

Comparative Map Data
PLCG1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12429,198,536 - 29,213,899 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2429,198,556 - 29,214,714 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2428,823,106 - 28,859,401 (+)NCBI
ROS_Cfam_1.02429,883,241 - 29,919,530 (+)NCBI
UMICH_Zoey_3.12429,152,120 - 29,188,420 (+)NCBI
UNSW_CanFamBas_1.02429,256,001 - 29,292,271 (+)NCBI
UU_Cfam_GSD_1.02429,752,157 - 29,788,483 (+)NCBI
PLCG1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2041,136,960 - 41,196,801 (+)EnsemblGRCh38hg38GRCh38
GRCh382041,137,519 - 41,177,626 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372039,766,183 - 39,806,266 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362039,199,575 - 39,237,771 (+)NCBINCBI36hg18NCBI36
Build 342039,199,574 - 39,237,771NCBI
Celera2036,476,730 - 36,514,924 (+)NCBI
Cytogenetic Map20q12NCBI
HuRef2036,504,215 - 36,542,409 (+)NCBIHuRef
CHM1_12039,670,573 - 39,708,755 (+)NCBICHM1_1
Plcg1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392160,573,230 - 160,617,680 (+)NCBIGRCm39mm39
GRCm39 Ensembl2160,573,220 - 160,617,680 (+)Ensembl
GRCm382160,731,310 - 160,775,760 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2160,731,300 - 160,775,760 (+)EnsemblGRCm38mm10GRCm38
MGSCv372160,557,046 - 160,601,496 (+)NCBIGRCm37mm9NCBIm37
MGSCv362160,422,751 - 160,467,201 (+)NCBImm8
Celera2166,663,373 - 166,707,819 (+)NCBICelera
Cytogenetic Map2H2NCBI
cM Map280.97NCBI
Plcg1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23149,385,587 - 149,416,330 (+)NCBI
Rnor_6.0 Ensembl3156,727,642 - 156,758,307 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.03156,727,642 - 156,758,307 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03162,957,126 - 162,987,842 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43151,522,949 - 151,553,998 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13151,428,984 - 151,460,034 (+)NCBI
Celera3148,059,477 - 148,090,220 (+)NCBICelera
RH 3.4 Map31368.6RGD
Cytogenetic Map3q42NCBI
Plcg1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544515,787,496 - 15,823,859 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544515,787,496 - 15,823,859 (-)NCBIChiLan1.0ChiLan1.0
PLCG1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12038,577,199 - 38,615,149 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2038,572,709 - 38,615,145 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02037,477,077 - 37,515,854 (+)NCBIMhudiblu_PPA_v0panPan3
Plcg1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640178,117,909 - 178,150,680 (+)NCBI
SpeTri2.0NW_004936561598,372 - 631,575 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLCG1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1743,809,677 - 43,844,555 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11743,810,003 - 43,844,553 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21749,203,540 - 49,238,416 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PLCG1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1222,599,547 - 22,638,394 (-)NCBI
Vero_WHO_p1.0NW_02366605071,416,788 - 71,455,730 (-)NCBI
Plcg1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249191,766,533 - 1,800,130 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 4 1 17 1 6 1 6 12 8 10 6
Low 1 4 5 5 5 6
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005635060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022408860 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038433833 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038433834 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038457654 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038457655 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038508979 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038508980 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038572317 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038572318 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038636570 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038636571 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000024 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000265 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000024 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000014441   ⟹   ENSCAFP00000013354
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2429,198,556 - 29,212,611 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000070025   ⟹   ENSCAFP00000046841
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2429,198,556 - 29,214,714 (+)Ensembl
RefSeq Acc Id: XM_038433833   ⟹   XP_038289761
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02429,883,241 - 29,919,530 (+)NCBI
RefSeq Acc Id: XM_038433834   ⟹   XP_038289762
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02429,883,262 - 29,919,530 (+)NCBI
RefSeq Acc Id: XM_038457654   ⟹   XP_038313582
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha2428,823,106 - 28,859,401 (+)NCBI
RefSeq Acc Id: XM_038457655   ⟹   XP_038313583
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha2428,823,127 - 28,859,401 (+)NCBI
RefSeq Acc Id: XM_038508979   ⟹   XP_038364907
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12429,152,120 - 29,188,420 (+)NCBI
RefSeq Acc Id: XM_038508980   ⟹   XP_038364908
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12429,152,141 - 29,188,420 (+)NCBI
RefSeq Acc Id: XM_038572317   ⟹   XP_038428245
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02429,752,157 - 29,788,483 (+)NCBI
RefSeq Acc Id: XM_038572318   ⟹   XP_038428246
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02429,752,178 - 29,788,483 (+)NCBI
RefSeq Acc Id: XM_038636570   ⟹   XP_038492498
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02429,256,001 - 29,292,271 (+)NCBI
RefSeq Acc Id: XM_038636571   ⟹   XP_038492499
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02429,256,022 - 29,292,271 (+)NCBI
Reference Sequences
RefSeq Acc Id: ENSCAFP00000046841   ⟸   ENSCAFT00000070025
RefSeq Acc Id: ENSCAFP00000013354   ⟸   ENSCAFT00000014441
RefSeq Acc Id: XP_038364907   ⟸   XM_038508979
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038364908   ⟸   XM_038508980
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038492498   ⟸   XM_038636570
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038492499   ⟸   XM_038636571
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038289761   ⟸   XM_038433833
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038289762   ⟸   XM_038433834
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038313582   ⟸   XM_038457654
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038313583   ⟸   XM_038457655
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038428245   ⟸   XM_038572317
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038428246   ⟸   XM_038572318
- Peptide Label: isoform X2
Protein Domains
C2   EF-hand   PH   PI-PLC Y-box   SH2   SH3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000009082 Ensembl, ENTREZGENE
NCBI Gene PLCG1 ENTREZGENE
VGNC ID VGNC:44651 ENTREZGENE