ERBB4 (erb-b2 receptor tyrosine kinase 4) - Rat Genome Database

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Gene: ERBB4 (erb-b2 receptor tyrosine kinase 4) Canis lupus familiaris
Analyze
Symbol: ERBB4
Name: erb-b2 receptor tyrosine kinase 4
RGD ID: 12144612
Description: ENCODES a protein that exhibits ATP binding (inferred); epidermal growth factor receptor activity (inferred); epidermal growth factor receptor binding (inferred); INVOLVED IN cell fate commitment (ortholog); cellular response to epidermal growth factor stimulus (ortholog); establishment of planar polarity involved in nephron morphogenesis (ortholog); PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog); amyotrophic lateral sclerosis type 10 (ortholog); amyotrophic lateral sclerosis type 19 (ortholog); FOUND IN caveola (ortholog); dendrite (ortholog); GABA-ergic synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: receptor tyrosine-protein kinase erbB-4; v-erb-a erythroblastic leukemia viral oncogene homolog 4; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13719,029,647 - 20,134,576 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3719,037,217 - 20,134,426 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3719,902,993 - 21,014,297 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03718,975,969 - 20,127,356 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3718,980,387 - 20,127,189 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13718,924,908 - 20,033,426 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03718,881,529 - 19,982,057 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03718,890,858 - 19,999,263 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
cardiac muscle tissue regeneration  (IEA)
cell fate commitment  (IEA,ISO)
cell migration  (IEA)
cell surface receptor protein tyrosine kinase signaling pathway  (IEA)
cell surface receptor signaling pathway  (IEA)
cell surface receptor signaling pathway via JAK-STAT  (IEA)
cellular response to epidermal growth factor stimulus  (IEA,ISO)
central nervous system morphogenesis  (IEA)
embryonic pattern specification  (IEA)
epidermal growth factor receptor signaling pathway  (IEA)
ERBB signaling pathway  (IEA)
ERBB2-ERBB4 signaling pathway  (IEA)
ERBB4 signaling pathway  (IEA)
ERBB4-ERBB4 signaling pathway  (IEA)
establishment of planar polarity involved in nephron morphogenesis  (IEA,ISO)
heart development  (IEA,ISO)
lactation  (IEA)
mammary gland alveolus development  (IEA)
mammary gland development  (ISO)
mammary gland epithelial cell differentiation  (IEA)
mitochondrial fragmentation involved in apoptotic process  (IEA)
negative regulation of apoptotic process  (IEA,ISO)
negative regulation of cell population proliferation  (IEA)
negative regulation of muscle cell apoptotic process  (ISO)
negative regulation of neuron migration  (ISO)
nervous system development  (IEA,ISO)
neural crest cell migration  (IEA)
neurogenesis  (IEA)
neurotransmitter receptor localization to postsynaptic specialization membrane  (IEA)
olfactory bulb interneuron differentiation  (IEA)
positive regulation of apoptotic process  (ISO)
positive regulation of cardiac muscle cell proliferation  (IEA)
positive regulation of cell migration  (ISO)
positive regulation of cell population proliferation  (IEA,ISO)
positive regulation of DNA-templated transcription  (IEA)
positive regulation of epithelial cell proliferation  (ISO)
positive regulation of ERK1 and ERK2 cascade  (IEA)
positive regulation of glucose import  (ISO)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction  (IEA,ISO)
positive regulation of phospholipid biosynthetic process  (ISO)
positive regulation of protein localization to cell surface  (IEA,ISO)
positive regulation of receptor signaling pathway via JAK-STAT  (IEA)
positive regulation of synaptic transmission, GABAergic  (ISO)
positive regulation of tyrosine phosphorylation of STAT protein  (IEA)
regulation of cell communication  (IEA)
regulation of cell migration  (IEA)
regulation of cell population proliferation  (IEA)
regulation of signaling  (IEA)
response to hydrogen peroxide  (ISO)
response to progesterone  (ISO)
response to xenobiotic stimulus  (ISO)
signal transduction  (IEA)
surfactant homeostasis  (ISO)
synapse assembly  (IEA)
synapse maturation  (ISO)
telencephalon development  (ISO)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:19010331   PMID:19193720   PMID:22301074   PMID:30032202   PMID:33508276  


Genomics

Comparative Map Data
ERBB4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13719,029,647 - 20,134,576 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3719,037,217 - 20,134,426 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3719,902,993 - 21,014,297 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03718,975,969 - 20,127,356 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3718,980,387 - 20,127,189 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13718,924,908 - 20,033,426 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03718,881,529 - 19,982,057 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03718,890,858 - 19,999,263 (-)NCBIUU_Cfam_GSD_1.0
ERBB4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382211,375,717 - 212,538,802 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2211,375,717 - 212,538,841 (-)EnsemblGRCh38hg38GRCh38
GRCh372212,240,442 - 213,403,526 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362211,948,687 - 213,111,597 (-)NCBINCBI36Build 36hg18NCBI36
Build 342212,072,320 - 213,228,793NCBI
Celera2206,008,419 - 207,168,130 (-)NCBICelera
Cytogenetic Map2q34NCBI
HuRef2204,087,816 - 205,252,852 (-)NCBIHuRef
CHM1_12212,246,189 - 213,409,602 (-)NCBICHM1_1
T2T-CHM13v2.02211,856,201 - 213,019,445 (-)NCBIT2T-CHM13v2.0
Erbb4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39168,071,063 - 69,147,756 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl168,071,345 - 69,147,218 (-)EnsemblGRCm39 Ensembl
GRCm38168,031,884 - 69,108,576 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl168,032,186 - 69,108,059 (-)EnsemblGRCm38mm10GRCm38
MGSCv37168,086,540 - 69,154,633 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36167,973,174 - 69,041,267 (-)NCBIMGSCv36mm8
Celera168,604,658 - 69,678,621 (-)NCBICelera
Cytogenetic Map1C3NCBI
cM Map133.8NCBI
Erbb4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8976,973,386 - 78,045,633 (-)NCBIGRCr8
mRatBN7.2969,523,733 - 70,596,743 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl969,531,481 - 70,596,595 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx978,025,868 - 79,086,390 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0983,154,766 - 84,215,249 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0981,560,145 - 82,620,859 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0975,021,790 - 76,178,936 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl975,021,790 - 75,528,644 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0974,804,287 - 75,310,350 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4966,843,898 - 67,967,970 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1966,990,879 - 68,114,952 (-)NCBI
Celera967,006,553 - 68,064,842 (-)NCBICelera
Cytogenetic Map9q32-q33NCBI
Erbb4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554573,177,991 - 4,228,558 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554573,177,905 - 4,236,152 (+)NCBIChiLan1.0ChiLan1.0
ERBB4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213113,991,295 - 115,165,716 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B114,006,258 - 115,180,343 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B98,625,630 - 99,795,371 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B217,107,266 - 218,272,621 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B217,069,644 - 218,272,006 (-)Ensemblpanpan1.1panPan2
Erbb4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303167,518,016 - 168,559,414 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365864,066,498 - 5,100,035 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365864,065,767 - 5,100,690 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ERBB4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15113,974,437 - 115,096,565 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115113,966,573 - 115,096,984 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215125,910,709 - 126,652,753 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ERBB4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11097,099,090 - 98,281,697 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666040101,138,707 - 102,297,290 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Erbb4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247653,613,379 - 4,734,585 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247653,612,781 - 4,742,219 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ERBB4
16519 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 1 7
Low 5 9 2 5 8 7 1
Below cutoff 5 7 1 5 1 6 4 3 5

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003434277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_003640190 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_003640191 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_003640192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022415050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022415051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022415052 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038447855 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038447856 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038447857 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038447858 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038447859 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038463588 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038521881 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038521882 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038521883 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038521884 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038521885 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038585647 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038585648 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038585649 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038585650 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038585651 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038650031 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038650032 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038650033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038650034 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038650035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000357 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000368 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSCAFT00000022535   ⟹   ENSCAFP00000020924
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3719,037,217 - 19,777,746 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000064322   ⟹   ENSCAFP00000056010
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3719,037,217 - 19,741,464 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000071657   ⟹   ENSCAFP00000046067
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3719,037,217 - 20,134,426 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000075474   ⟹   ENSCAFP00000046598
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3719,037,217 - 19,741,464 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000076373   ⟹   ENSCAFP00000064758
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3719,037,217 - 19,870,965 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000080671   ⟹   ENSCAFP00000062810
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3719,037,217 - 19,741,464 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000082727   ⟹   ENSCAFP00000058824
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3719,037,217 - 19,870,965 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000091250   ⟹   ENSCAFP00000044233
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3719,037,217 - 19,741,464 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000093639   ⟹   ENSCAFP00000048210
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3719,037,217 - 19,741,464 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845033485   ⟹   ENSCAFP00845026212
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3718,980,387 - 20,127,189 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845033862   ⟹   ENSCAFP00845026498
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3718,980,387 - 19,669,996 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845034087   ⟹   ENSCAFP00845026686
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3718,980,387 - 19,669,996 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845034317   ⟹   ENSCAFP00845026863
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3718,980,387 - 19,669,996 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845034477   ⟹   ENSCAFP00845027004
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3718,980,387 - 19,669,996 (-)Ensembl
RefSeq Acc Id: XM_003434277   ⟹   XP_003434325
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.13719,029,647 - 20,134,576 (-)NCBI
Dog10K_Boxer_Tasha3719,902,993 - 21,014,296 (-)NCBI
Sequence:
RefSeq Acc Id: XM_003640190   ⟹   XP_003640238
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.13719,029,647 - 20,134,576 (-)NCBI
Dog10K_Boxer_Tasha3719,902,993 - 21,014,296 (-)NCBI
Sequence:
RefSeq Acc Id: XM_003640191   ⟹   XP_003640239
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.13719,029,647 - 20,134,576 (-)NCBI
Dog10K_Boxer_Tasha3719,902,993 - 21,014,297 (-)NCBI
Sequence:
RefSeq Acc Id: XM_003640192   ⟹   XP_003640240
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.13719,029,647 - 20,134,576 (-)NCBI
Dog10K_Boxer_Tasha3719,902,993 - 21,014,297 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038447855   ⟹   XP_038303783
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03718,975,969 - 20,127,355 (-)NCBI
RefSeq Acc Id: XM_038447856   ⟹   XP_038303784
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03718,975,969 - 20,127,356 (-)NCBI
RefSeq Acc Id: XM_038447857   ⟹   XP_038303785
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03718,975,969 - 20,127,356 (-)NCBI
RefSeq Acc Id: XM_038447858   ⟹   XP_038303786
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03718,975,969 - 20,127,356 (-)NCBI
RefSeq Acc Id: XM_038447859   ⟹   XP_038303787
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03718,975,969 - 19,448,455 (-)NCBI
RefSeq Acc Id: XM_038463588   ⟹   XP_038319516
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha3719,902,993 - 20,381,664 (-)NCBI
RefSeq Acc Id: XM_038521881   ⟹   XP_038377809
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.13718,924,908 - 20,033,425 (-)NCBI
RefSeq Acc Id: XM_038521882   ⟹   XP_038377810
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.13718,924,908 - 20,033,425 (-)NCBI
RefSeq Acc Id: XM_038521883   ⟹   XP_038377811
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.13718,924,908 - 20,033,425 (-)NCBI
RefSeq Acc Id: XM_038521884   ⟹   XP_038377812
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.13718,924,908 - 20,033,426 (-)NCBI
RefSeq Acc Id: XM_038521885   ⟹   XP_038377813
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.13718,924,908 - 19,401,595 (-)NCBI
RefSeq Acc Id: XM_038585647   ⟹   XP_038441575
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.03718,890,858 - 19,999,262 (-)NCBI
RefSeq Acc Id: XM_038585648   ⟹   XP_038441576
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.03718,890,858 - 19,999,262 (-)NCBI
RefSeq Acc Id: XM_038585649   ⟹   XP_038441577
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.03718,890,858 - 19,999,262 (-)NCBI
RefSeq Acc Id: XM_038585650   ⟹   XP_038441578
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.03718,890,858 - 19,999,263 (-)NCBI
RefSeq Acc Id: XM_038585651   ⟹   XP_038441579
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.03718,890,858 - 19,366,205 (-)NCBI
RefSeq Acc Id: XM_038650031   ⟹   XP_038505959
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.03718,881,529 - 19,982,056 (-)NCBI
RefSeq Acc Id: XM_038650032   ⟹   XP_038505960
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.03718,881,529 - 19,982,057 (-)NCBI
RefSeq Acc Id: XM_038650033   ⟹   XP_038505961
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.03718,881,529 - 19,982,056 (-)NCBI
RefSeq Acc Id: XM_038650034   ⟹   XP_038505962
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.03718,881,529 - 19,982,057 (-)NCBI
RefSeq Acc Id: XM_038650035   ⟹   XP_038505963
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.03718,881,529 - 19,352,828 (-)NCBI
Protein Sequences
Protein RefSeqs XP_003434325 (Get FASTA)   NCBI Sequence Viewer  
  XP_003640238 (Get FASTA)   NCBI Sequence Viewer  
  XP_003640239 (Get FASTA)   NCBI Sequence Viewer  
  XP_003640240 (Get FASTA)   NCBI Sequence Viewer  
  XP_038303783 (Get FASTA)   NCBI Sequence Viewer  
  XP_038303784 (Get FASTA)   NCBI Sequence Viewer  
  XP_038303785 (Get FASTA)   NCBI Sequence Viewer  
  XP_038303786 (Get FASTA)   NCBI Sequence Viewer  
  XP_038303787 (Get FASTA)   NCBI Sequence Viewer  
  XP_038319516 (Get FASTA)   NCBI Sequence Viewer  
  XP_038377809 (Get FASTA)   NCBI Sequence Viewer  
  XP_038377810 (Get FASTA)   NCBI Sequence Viewer  
  XP_038377811 (Get FASTA)   NCBI Sequence Viewer  
  XP_038377812 (Get FASTA)   NCBI Sequence Viewer  
  XP_038377813 (Get FASTA)   NCBI Sequence Viewer  
  XP_038441575 (Get FASTA)   NCBI Sequence Viewer  
  XP_038441576 (Get FASTA)   NCBI Sequence Viewer  
  XP_038441577 (Get FASTA)   NCBI Sequence Viewer  
  XP_038441578 (Get FASTA)   NCBI Sequence Viewer  
  XP_038441579 (Get FASTA)   NCBI Sequence Viewer  
  XP_038505959 (Get FASTA)   NCBI Sequence Viewer  
  XP_038505960 (Get FASTA)   NCBI Sequence Viewer  
  XP_038505961 (Get FASTA)   NCBI Sequence Viewer  
  XP_038505962 (Get FASTA)   NCBI Sequence Viewer  
  XP_038505963 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCAFP00000020924.5
  ENSCAFP00000046067.1
  ENSCAFP00000046598.2
  ENSCAFP00000056010.1
  ENSCAFP00000064758.2
  ENSCAFP00030027694.1
  ENSCAFP00030027804.1
  ENSCAFP00030027933.1
  ENSCAFP00030028067.1
  ENSCAFP00030028254.1
  ENSCAFP00030028483.1
  ENSCAFP00040026439.1
  ENSCAFP00040026490.1
  ENSCAFP00040026580.1
  ENSCAFP00040026810.1
  ENSCAFP00040026898.1
  ENSCAFP00040027119.1
  ENSCAFP00845026212
  ENSCAFP00845026212.1
  ENSCAFP00845026498.1
  ENSCAFP00845026686
  ENSCAFP00845026686.1
  ENSCAFP00845026863
  ENSCAFP00845026863.1
  ENSCAFP00845027004.1
RefSeq Acc Id: XP_003640238   ⟸   XM_003640190
- Peptide Label: isoform X1
- UniProtKB: A0A8C0NV16 (UniProtKB/TrEMBL),   A0A8I3S0T0 (UniProtKB/TrEMBL),   A0A8P0PDF6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003434325   ⟸   XM_003434277
- Peptide Label: isoform X3
- UniProtKB: A0A8C0NVA0 (UniProtKB/TrEMBL),   A0A8P0PDF6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003640239   ⟸   XM_003640191
- Peptide Label: isoform X2
- UniProtKB: A0A8C0NMX2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003640240   ⟸   XM_003640192
- Peptide Label: isoform X4
- UniProtKB: A0A8P0PDF6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000056010   ⟸   ENSCAFT00000064322
RefSeq Acc Id: ENSCAFP00000048210   ⟸   ENSCAFT00000093639
RefSeq Acc Id: ENSCAFP00000044233   ⟸   ENSCAFT00000091250
RefSeq Acc Id: ENSCAFP00000064758   ⟸   ENSCAFT00000076373
RefSeq Acc Id: ENSCAFP00000058824   ⟸   ENSCAFT00000082727
RefSeq Acc Id: ENSCAFP00000062810   ⟸   ENSCAFT00000080671
RefSeq Acc Id: ENSCAFP00000046598   ⟸   ENSCAFT00000075474
RefSeq Acc Id: ENSCAFP00000020924   ⟸   ENSCAFT00000022535
RefSeq Acc Id: ENSCAFP00000046067   ⟸   ENSCAFT00000071657
RefSeq Acc Id: XP_038377812   ⟸   XM_038521884
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038377811   ⟸   XM_038521883
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038377809   ⟸   XM_038521881
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038377810   ⟸   XM_038521882
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038377813   ⟸   XM_038521885
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038505962   ⟸   XM_038650034
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038505960   ⟸   XM_038650032
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038505961   ⟸   XM_038650033
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038505959   ⟸   XM_038650031
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038505963   ⟸   XM_038650035
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038303785   ⟸   XM_038447857
- Peptide Label: isoform X3
- UniProtKB: A0A8C0NVA0 (UniProtKB/TrEMBL),   A0A8P0PDF6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038303786   ⟸   XM_038447858
- Peptide Label: isoform X4
- UniProtKB: A0A8P0PDF6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038303784   ⟸   XM_038447856
- Peptide Label: isoform X2
- UniProtKB: A0A8C0NMX2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038303783   ⟸   XM_038447855
- Peptide Label: isoform X1
- UniProtKB: A0A8C0NV16 (UniProtKB/TrEMBL),   A0A8I3S0T0 (UniProtKB/TrEMBL),   A0A8P0PDF6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038303787   ⟸   XM_038447859
- Peptide Label: isoform X5
- UniProtKB: A0A8C0NKC8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038319516   ⟸   XM_038463588
- Peptide Label: isoform X5
- UniProtKB: A0A8C0NKC8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038441578   ⟸   XM_038585650
- Peptide Label: isoform X4
- UniProtKB: A0A8P0PDF6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038441577   ⟸   XM_038585649
- Peptide Label: isoform X3
- UniProtKB: A0A8C0NVA0 (UniProtKB/TrEMBL),   A0A8P0PDF6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038441575   ⟸   XM_038585647
- Peptide Label: isoform X1
- UniProtKB: A0A8C0NV16 (UniProtKB/TrEMBL),   A0A8I3S0T0 (UniProtKB/TrEMBL),   A0A8P0PDF6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038441576   ⟸   XM_038585648
- Peptide Label: isoform X2
- UniProtKB: A0A8C0NMX2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038441579   ⟸   XM_038585651
- Peptide Label: isoform X5
- UniProtKB: A0A8C0NKC8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845026863   ⟸   ENSCAFT00845034317
RefSeq Acc Id: ENSCAFP00845026498   ⟸   ENSCAFT00845033862
RefSeq Acc Id: ENSCAFP00845026212   ⟸   ENSCAFT00845033485
RefSeq Acc Id: ENSCAFP00845026686   ⟸   ENSCAFT00845034087
RefSeq Acc Id: ENSCAFP00845027004   ⟸   ENSCAFT00845034477
Protein Domains
Protein kinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000023258 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030016480 UniProtKB/TrEMBL
  ENSCAFG00040014964 UniProtKB/TrEMBL
  ENSCAFG00845018700 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000022535.5 UniProtKB/TrEMBL
  ENSCAFT00000064322.2 UniProtKB/TrEMBL
  ENSCAFT00000071657.2 UniProtKB/TrEMBL
  ENSCAFT00000075474.2 UniProtKB/TrEMBL
  ENSCAFT00000076373.2 UniProtKB/TrEMBL
  ENSCAFT00030031756.1 UniProtKB/TrEMBL
  ENSCAFT00030031884.1 UniProtKB/TrEMBL
  ENSCAFT00030032040.1 UniProtKB/TrEMBL
  ENSCAFT00030032173.1 UniProtKB/TrEMBL
  ENSCAFT00030032392.1 UniProtKB/TrEMBL
  ENSCAFT00030032652.1 UniProtKB/TrEMBL
  ENSCAFT00040030424.1 UniProtKB/TrEMBL
  ENSCAFT00040030479.1 UniProtKB/TrEMBL
  ENSCAFT00040030580.1 UniProtKB/TrEMBL
  ENSCAFT00040030843.1 UniProtKB/TrEMBL
  ENSCAFT00040030948.1 UniProtKB/TrEMBL
  ENSCAFT00040031202.1 UniProtKB/TrEMBL
  ENSCAFT00845033485 ENTREZGENE
  ENSCAFT00845033485.1 UniProtKB/TrEMBL
  ENSCAFT00845033862.1 UniProtKB/TrEMBL
  ENSCAFT00845034087 ENTREZGENE
  ENSCAFT00845034087.1 UniProtKB/TrEMBL
  ENSCAFT00845034317 ENTREZGENE
  ENSCAFT00845034317.1 UniProtKB/TrEMBL
  ENSCAFT00845034477.1 UniProtKB/TrEMBL
Gene3D-CATH 3.80.20.20 UniProtKB/TrEMBL
  6.10.250.880 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Furin-like_Cys-rich_dom UniProtKB/TrEMBL
  Furin_repeat UniProtKB/TrEMBL
  GF_recep_IV UniProtKB/TrEMBL
  Growth_fac_rcpt_cys_sf UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Rcpt_L-dom UniProtKB/TrEMBL
  Rcpt_L-dom_sf UniProtKB/TrEMBL
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/TrEMBL
  TM_ErbB1 UniProtKB/TrEMBL
  Tyr_kinase_AS UniProtKB/TrEMBL
  Tyr_kinase_cat_dom UniProtKB/TrEMBL
  Tyr_kinase_EGF/ERB/XmrK_rcpt UniProtKB/TrEMBL
KEGG Report cfa:488508 UniProtKB/TrEMBL
NCBI Gene ERBB4 ENTREZGENE
PANTHER RECEPTOR TYROSINE-PROTEIN KINASE ERBB-4 UniProtKB/TrEMBL
  TYROSINE-PROTEIN KINASE RECEPTOR UniProtKB/TrEMBL
Pfam Furin-like UniProtKB/TrEMBL
  GF_recep_IV UniProtKB/TrEMBL
  PK_Tyr_Ser-Thr UniProtKB/TrEMBL
  Recep_L_domain UniProtKB/TrEMBL
  TM_ErbB1 UniProtKB/TrEMBL
PIRSF TyrPK_EGF-R UniProtKB/TrEMBL
PRINTS TYRKINASE UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_TYR UniProtKB/TrEMBL
SMART SM00261 UniProtKB/TrEMBL
  TyrKc UniProtKB/TrEMBL
Superfamily-SCOP L domain-like UniProtKB/TrEMBL
  SSF56112 UniProtKB/TrEMBL
  SSF57184 UniProtKB/TrEMBL
UniProt A0A8C0NKC8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0NMX2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0NV16 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0NVA0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0P0U4_CANLF UniProtKB/TrEMBL
  A0A8C0STC6_CANLF UniProtKB/TrEMBL
  A0A8I3P422_CANLF UniProtKB/TrEMBL
  A0A8I3P968_CANLF UniProtKB/TrEMBL
  A0A8I3PAL2_CANLF UniProtKB/TrEMBL
  A0A8I3S0T0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3S108_CANLF UniProtKB/TrEMBL
  A0A8P0P5H1_CANLF UniProtKB/TrEMBL
  A0A8P0PDF6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0SIZ8_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:40437 ENTREZGENE