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Gene: WRAP53 (WD repeat containing antisense to TP53) Canis lupus familiaris

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Symbol:

WRAP53 (Ensembl: EFNB3)

Name:

WD repeat containing antisense to TP53

RGD ID:

12124119

Description:

ENCODES a protein that exhibits histone binding (inferred); identical protein binding (inferred); protein carrier chaperone (inferred); INVOLVED IN Cajal body organization (inferred); positive regulation of DNA repair (inferred); positive regulation of double-strand break repair (inferred); ASSOCIATED WITH Autosomal Recessive Dyskeratosis Congenita (ortholog); autosomal recessive dyskeratosis congenita 3 (ortholog); Body Weight (ortholog); FOUND IN Cajal body (inferred); chromosome, telomeric region (inferred); cytosol (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

telomerase Cajal body protein 1; WD repeat domain 79; WDR79

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	32,574,153 - 32,586,222 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	32,574,134 - 32,594,333 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	32,712,138 - 32,725,180 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	32,677,789 - 32,690,832 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	32,678,578 - 32,690,834 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	32,645,668 - 32,658,710 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	32,601,891 - 32,614,933 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	32,780,842 - 32,793,885 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
WRAP53	Dog	breast cancer	no_association	ISO	RGD:1605665	9068941	DNA:SNP: : rs2287499(human)	RGD	PMID:25134915\|REF_RGD_ID:21081531
WRAP53	Dog	colorectal cancer	onset	ISO	RGD:1605665	9068941		RGD	PMID:26013439\|REF_RGD_ID:21081528
WRAP53	Dog	colorectal cancer		ISO	RGD:1605665	9068941		RGD	PMID:30175821\|REF_RGD_ID:21081520
WRAP53	Dog	esophagus squamous cell carcinoma	disease_progression	ISO	RGD:1605665	9068941		RGD	PMID:24626331\|REF_RGD_ID:21081532
WRAP53	Dog	glottis squamous cell carcinoma	disease_progression	ISO	RGD:1605665	9068941		RGD	PMID:28849066\|REF_RGD_ID:21081521
WRAP53	Dog	head and neck squamous cell carcinoma	treatment	ISO	RGD:1605665	9068941		RGD	PMID:25070141\|PMID:25456005\|REF_RGD_ID:21081529\|REF_RGD_ID:21081533
WRAP53	Dog	hepatocellular carcinoma		ISO	RGD:1605665	9068941	RNA:increased expression:liver:	RGD	PMID:26551349\|REF_RGD_ID:11096781
WRAP53	Dog	lung adenocarcinoma	severity	ISO	RGD:1605665	9068941		RGD	PMID:28347242\|REF_RGD_ID:21081522
WRAP53	Dog	lung non-small cell carcinoma	disease_progression	ISO	RGD:1605665	9068941	RNA:increased expression:lung	RGD	PMID:31281482\|REF_RGD_ID:21081513
WRAP53	Dog	lung non-small cell carcinoma	disease_progression	ISO	RGD:1605665	9068941	DNA:hypermethylation:promoter	RGD	PMID:30344734\|REF_RGD_ID:21081519
WRAP53	Dog	Lymphatic Metastasis		ISO	RGD:1605665	9068941	associated with esophagus squamous cell carcinoma;	RGD	PMID:24626331\|REF_RGD_ID:21081532
WRAP53	Dog	Lymphatic Metastasis		ISO	RGD:1605665	9068941	associated with lung non-small cell carcinoma;	RGD	PMID:31281482\|REF_RGD_ID:21081513
WRAP53	Dog	nasopharynx carcinoma		ISO	RGD:1605665	9068941	associated with Epstein-Barr Virus Infections; protein:increased expression:nasopharynx epithelium	RGD	PMID:28607398\|REF_RGD_ID:21081524
WRAP53	Dog	ovarian cancer	disease_progression	ISO	RGD:1605665	9068941		RGD	PMID:26426684\|REF_RGD_ID:11522675
WRAP53	Dog	ovarian cancer	susceptibility	ISO	RGD:1605665	9068941	DNA:SNPs: :	RGD	PMID:23192612\|REF_RGD_ID:21081534
WRAP53	Dog	rectal benign neoplasm	treatment	ISO	RGD:1605665	9068941		RGD	PMID:22805008\|REF_RGD_ID:21081677

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
WRAP53	Dog	Autosomal Recessive Dyskeratosis Congenita		ISO	RGD:1605665	8554872	ClinVar Annotator: match by term: Dyskeratosis Congenita, Recessive	ClinVar	PMID:17576681\|PMID:25741868\|PMID:28492532\|PMID:9536098
WRAP53	Dog	autosomal recessive dyskeratosis congenita 3		ISO	RGD:1605665	8554872	ClinVar Annotator: match by term: Dyskeratosis congenita, autosomal recessive 3 \| ClinVar Annotator: match by more ...	ClinVar	PMID:17683073\|PMID:20301779\|PMID:21205863\|PMID:24033266\|PMID:25741868\|PMID:26822237\|PMID:28125078\|PMID:28492532\|PMID:29514627\|PMID:30552426\|PMID:32303682\|PMID:34573280\|PMID:36116037\|PMID:37149759
WRAP53	Dog	breast cancer		ISO	RGD:1605665	8554872	ClinVar Annotator: match by term: Malignant tumor of breast	ClinVar
WRAP53	Dog	common variable immunodeficiency		ISO	RGD:1605665	8554872	ClinVar Annotator: match by term: Common variable immunodeficiency	ClinVar	PMID:28492532
WRAP53	Dog	congenital myasthenic syndrome 2A		ISO	RGD:1605665	8554872	ClinVar Annotator: match by term: Congenital myasthenic syndrome 2A	ClinVar	PMID:28492532
WRAP53	Dog	Diamond-Blackfan anemia		ISO	RGD:1605665	8554872	ClinVar Annotator: match by term: Diamond-Blackfan anemia	ClinVar	PMID:20522432\|PMID:21056402\|PMID:22267198\|PMID:22387016\|PMID:23172776\|PMID:28492532
WRAP53	Dog	dyskeratosis congenita		ISO	RGD:1605665	8554872	ClinVar Annotator: match by term: Dyskeratosis congenita	ClinVar	PMID:17683073\|PMID:20522432\|PMID:21056402\|PMID:22267198\|PMID:22387016\|PMID:23172776\|PMID:24033266\|PMID:25741868\|PMID:26822237\|PMID:28125078\|PMID:28492532\|PMID:36116037
WRAP53	Dog	head and neck squamous cell carcinoma		ISO	RGD:1605665	8554872	ClinVar Annotator: match by term: Squamous cell carcinoma of the head and neck	ClinVar
WRAP53	Dog	Hereditary Neoplastic Syndromes		ISO	RGD:1605665	8554872	ClinVar Annotator: match by term: Hereditary Cancer Syndrome \| ClinVar Annotator: match by term: Hereditary more ...	ClinVar	PMID:17576681\|PMID:21205863\|PMID:25741868\|PMID:28492532\|PMID:9536098
WRAP53	Dog	Hereditary Neoplastic Syndromes		ISO	RGD:1605665	8554872	ClinVar Annotator: match by term: Hereditary Cancer Syndrome \| ClinVar Annotator: match by term: Hereditary more ...	ClinVar	PMID:17576681\|PMID:20301779\|PMID:21205863\|PMID:25741868\|PMID:28492532\|PMID:32303682\|PMID:37149759\|PMID:9536098
WRAP53	Dog	Li-Fraumeni syndrome		ISO	RGD:1605665	8554872	ClinVar Annotator: match by term: Li-Fraumeni syndrome \| ClinVar Annotator: match by term: Sarcoma family more ...	ClinVar	PMID:17576681\|PMID:17683073\|PMID:18511570\|PMID:20522432\|PMID:21056402\|PMID:23172776\|PMID:24033266\|PMID:25741868\|PMID:25762628\|PMID:26681312\|PMID:28492532\|PMID:9242456\|PMID:9536098
WRAP53	Dog	Li-Fraumeni syndrome		ISO	RGD:1605665	8554872	ClinVar Annotator: match by term: Li-Fraumeni syndrome \| ClinVar Annotator: match by term: Sarcoma family more ...	ClinVar	PMID:10980596\|PMID:17576681\|PMID:17683073\|PMID:18511570\|PMID:20522432\|PMID:21056402\|PMID:22267198\|PMID:22387016\|PMID:23172776\|PMID:24033266\|PMID:25741868\|PMID:25762628\|PMID:26681312\|PMID:28369373\|PMID:28492532\|PMID:32191290\|PMID:9242456\|PMID:9536098
WRAP53	Dog	Li-Fraumeni syndrome 1		ISO	RGD:1605665	8554872	ClinVar Annotator: match by term: Li-Fraumeni syndrome 1	ClinVar
WRAP53	Dog	very long chain acyl-CoA dehydrogenase deficiency		ISO	RGD:1605665	8554872	ClinVar Annotator: match by term: Very long chain acyl-CoA dehydrogenase deficiency	ClinVar	PMID:11590124\|PMID:28492532\|PMID:9973285

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
WRAP53	Dog	Body Weight		ISO	RGD:1605665	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:31243981

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
WRAP53	Dog	autosomal recessive dyskeratosis congenita 3		ISO	RGD:1605665	7240710		OMIM

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
WRAP53	Dog	Cajal body organization	involved_in	IBA	FB:FBgn0031782\|PANTHER:PTN000996134\|UniProtKB:Q9BUR4	150520179		GO_Central	GO_REF:0000033
WRAP53	Dog	Cajal body organization	involved_in	IEA	UniProtKB:Q9BUR4\|ensembl:ENSP00000379727	150520179		Ensembl	GO_REF:0000107
WRAP53	Dog	positive regulation of DNA repair	involved_in	IEA	UniProtKB:Q9BUR4\|ensembl:ENSP00000379727	150520179		Ensembl	GO_REF:0000107
WRAP53	Dog	positive regulation of double-strand break repair	involved_in	IEA	UniProtKB:Q9BUR4\|ensembl:ENSP00000379727	150520179		Ensembl	GO_REF:0000107
WRAP53	Dog	positive regulation of double-strand break repair via homologous recombination	involved_in	IEA	UniProtKB:Q9BUR4\|ensembl:ENSP00000379727	150520179		Ensembl	GO_REF:0000107
WRAP53	Dog	positive regulation of double-strand break repair via nonhomologous end joining	involved_in	IEA	UniProtKB:Q9BUR4\|ensembl:ENSP00000379727	150520179		Ensembl	GO_REF:0000107
WRAP53	Dog	positive regulation of establishment of protein localization to telomere	involved_in	IEA	UniProtKB:Q9BUR4\|ensembl:ENSP00000379727	150520179		Ensembl	GO_REF:0000107
WRAP53	Dog	positive regulation of telomere maintenance via telomerase	acts_upstream_of	IEA	UniProtKB:Q9BUR4\|ensembl:ENSP00000379727	150520179		Ensembl	GO_REF:0000107
WRAP53	Dog	protein localization to Cajal body	involved_in	IEA	UniProtKB:Q9BUR4\|ensembl:ENSP00000379727	150520179		Ensembl	GO_REF:0000107
WRAP53	Dog	RNA folding	involved_in	IEA	UniProtKB:Q9BUR4\|ensembl:ENSP00000379727	150520179		Ensembl	GO_REF:0000107
WRAP53	Dog	scaRNA localization to Cajal body	involved_in	IEA	UniProtKB:Q9BUR4\|ensembl:ENSP00000379727	150520179		Ensembl	GO_REF:0000107
WRAP53	Dog	telomerase RNA localization to Cajal body	involved_in	IEA	UniProtKB:Q9BUR4\|ensembl:ENSP00000379727	150520179		Ensembl	GO_REF:0000107
WRAP53	Dog	telomere formation via telomerase	involved_in	IEA	UniProtKB:Q9BUR4\|ensembl:ENSP00000379727	150520179		Ensembl	GO_REF:0000107
WRAP53	Dog	telomere maintenance via telomerase	involved_in	IEA	UniProtKB:Q9BUR4\|ensembl:ENSP00000379727	150520179		Ensembl	GO_REF:0000107

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
WRAP53	Dog	Cajal body	located_in	IEA	UniProtKB:Q9BUR4\|ensembl:ENSP00000379727	150520179		Ensembl	GO_REF:0000107
WRAP53	Dog	Cajal body	is_active_in	IBA	FB:FBgn0031782\|PANTHER:PTN000996134\|UniProtKB:Q9BUR4	150520179		GO_Central	GO_REF:0000033
WRAP53	Dog	Cajal body	located_in	IEA	UniProtKB-SubCell:SL-0031	150520179		UniProt	GO_REF:0000044
WRAP53	Dog	chromosome, telomeric region	located_in	IEA	UniProtKB-SubCell:SL-0276	150520179		UniProt	GO_REF:0000044
WRAP53	Dog	cytosol	located_in	IEA	UniProtKB:Q9BUR4\|ensembl:ENSP00000379727	150520179		Ensembl	GO_REF:0000107
WRAP53	Dog	nuclear body	located_in	IEA	UniProtKB:Q9BUR4\|ensembl:ENSP00000379727	150520179		Ensembl	GO_REF:0000107
WRAP53	Dog	nucleoplasm	located_in	IEA	UniProtKB:Q9BUR4\|ensembl:ENSP00000379727	150520179		Ensembl	GO_REF:0000107
WRAP53	Dog	site of double-strand break	located_in	IEA	UniProtKB:Q9BUR4\|ensembl:ENSP00000379727	150520179		Ensembl	GO_REF:0000107
WRAP53	Dog	telomerase holoenzyme complex	part_of	IEA	UniProtKB:Q9BUR4\|ensembl:ENSP00000379727	150520179		Ensembl	GO_REF:0000107

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
WRAP53	Dog	histone binding	enables	IEA	UniProtKB:Q9BUR4\|ensembl:ENSP00000379727	150520179		Ensembl	GO_REF:0000107
WRAP53	Dog	identical protein binding	enables	IEA	UniProtKB:Q9BUR4\|ensembl:ENSP00000379727	150520179		Ensembl	GO_REF:0000107
WRAP53	Dog	protein binding	enables	ISO	UniProtKB:O77622	9068941	PMID:25467444	IntAct	PMID:25467444
WRAP53	Dog	protein binding	enables	ISO	UniProtKB:O14746\|UniProtKB:O60832	9068941	PMID:19179534	UniProt	PMID:19179534
WRAP53	Dog	protein binding	enables	ISO	UniProtKB:O60832\|UniProtKB:P40227	9068941	PMID:25467444	BHF-UCL	PMID:25467444
WRAP53	Dog	protein binding	enables	ISO	UniProtKB:P38432\|UniProtKB:Q16637	9068941	PMID:21072240	IntAct	PMID:21072240
WRAP53	Dog	protein binding	enables	ISO	UniProtKB:Q08AM6\|UniProtKB:Q5T6F2	9068941	PMID:32296183	IntAct	PMID:32296183
WRAP53	Dog	protein carrier chaperone	enables	IEA	UniProtKB:Q9BUR4\|ensembl:ENSP00000379727	150520179		Ensembl	GO_REF:0000107
WRAP53	Dog	protein-containing complex binding	enables	IEA	UniProtKB:Q9BUR4\|ensembl:ENSP00000379727	150520179		Ensembl	GO_REF:0000107
WRAP53	Dog	protein-folding chaperone binding	enables	IEA	UniProtKB:Q9BUR4\|ensembl:ENSP00000379727	150520179		Ensembl	GO_REF:0000107
WRAP53	Dog	RNA binding	enables	IEA	UniProtKB:Q9BUR4\|ensembl:ENSP00000379727	150520179		Ensembl	GO_REF:0000107
WRAP53	Dog	RNA binding	enables	IBA	FB:FBgn0031782\|PANTHER:PTN000996134\|UniProtKB:Q9BUR4	150520179		GO_Central	GO_REF:0000033
WRAP53	Dog	RNA folding chaperone	enables	IEA	UniProtKB:Q8VC51\|UniProtKB:Q9BUR4\|ensembl:ENSMUSP00000047825\|ensembl:ENSP00000379727	150520179		Ensembl	GO_REF:0000107
WRAP53	Dog	telomerase RNA binding	enables	IEA	UniProtKB:Q9BUR4\|ensembl:ENSP00000379727	150520179		Ensembl	GO_REF:0000107
WRAP53	Dog	ubiquitin protein ligase binding	enables	IEA	UniProtKB:Q9BUR4\|ensembl:ENSP00000379727	150520179		Ensembl	GO_REF:0000107

PMID:22301074	PMID:30032202

WRAP53
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	32,574,153 - 32,586,222 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	32,574,134 - 32,594,333 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	32,712,138 - 32,725,180 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	32,677,789 - 32,690,832 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	32,678,578 - 32,690,834 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	32,645,668 - 32,658,710 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	32,601,891 - 32,614,933 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	32,780,842 - 32,793,885 (+)	NCBI		UU_Cfam_GSD_1.0

WRAP53
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	7,686,071 - 7,703,502 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	7,686,071 - 7,703,502 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	17	7,589,389 - 7,606,820 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	7,532,520 - 7,547,544 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	17	7,615,750 - 7,633,180 (+)	NCBI		Celera
Cytogenetic Map	17	p13.1	NCBI
HuRef	17	7,482,804 - 7,500,156 (+)	NCBI		HuRef
CHM1_1	17	7,598,524 - 7,615,973 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	17	7,590,175 - 7,607,622 (+)	NCBI		T2T-CHM13v2.0

Wrap53
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	69,452,580 - 69,471,076 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	69,452,584 - 69,471,081 (-)	Ensembl		GRCm39 Ensembl
GRCm38	11	69,561,754 - 69,580,250 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	69,561,758 - 69,580,255 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	69,375,256 - 69,392,826 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	69,377,949 - 69,395,519 (-)	NCBI		MGSCv36	mm8
Celera	11	76,524,707 - 76,542,284 (-)	NCBI		Celera
Cytogenetic Map	11	B3	NCBI
cM Map	11	42.81	NCBI

Wrap53
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	54,780,873 - 54,797,919 (-)	NCBI		GRCr8
mRatBN7.2	10	54,282,092 - 54,299,908 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	54,282,105 - 54,298,929 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	58,944,501 - 58,961,275 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	58,433,045 - 58,449,818 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	53,940,731 - 53,957,518 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	56,169,024 - 56,185,800 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	56,169,025 - 56,185,857 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	55,914,380 - 55,931,438 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	56,380,914 - 56,398,501 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	56,394,537 - 56,412,124 (-)	NCBI
Celera	10	53,436,325 - 53,453,155 (-)	NCBI		Celera
Cytogenetic Map	10	q24	NCBI

Wrap53
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955467	9,225,506 - 9,240,756 (-)	NCBI	ChiLan1.0	ChiLan1.0

WRAP53
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	15,280,889 - 15,298,965 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	17,246,094 - 17,265,011 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	7,715,897 - 7,735,873 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	7,707,220 - 7,723,410 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	7,707,221 - 7,723,394 (+)	Ensembl	panpan1.1		panPan2

Wrap53
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	47,461,298 - 47,478,596 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936595	936,487 - 952,791 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936595	936,184 - 952,784 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

WRAP53
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	52,954,669 - 52,968,364 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	52,954,674 - 52,968,371 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	55,205,960 - 55,219,648 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

WRAP53
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	7,065,531 - 7,085,590 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	7,066,333 - 7,085,625 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666059	14,323,308 - 14,343,301 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Wrap53
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624786	10,283,984 - 10,296,729 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624786	10,283,721 - 10,296,568 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in WRAP53
94 total Variants

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
6	5	5	23	22	16	6	6	6	6	33	22	12	14	10


RefSeq Transcripts	XM_005619990	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038475553	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038536723	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038600897	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038665443	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000062	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000089	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000371	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000026478 ⟹ ENSCAFP00000024592

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	5	32,574,134 - 32,586,202 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00000036506 ⟹ ENSCAFP00000031891

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	5	32,575,344 - 32,586,202 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00000042891 ⟹ ENSCAFP00000035853

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	5	32,588,333 - 32,594,333 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00000045758 ⟹ ENSCAFP00000036919

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	5	32,588,333 - 32,593,021 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00000069246 ⟹ ENSCAFP00000053849

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	5	32,574,134 - 32,594,333 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00000073485 ⟹ ENSCAFP00000057757

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	5	32,574,134 - 32,585,929 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845043832 ⟹ ENSCAFP00845034349

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	5	32,678,578 - 32,690,834 (+)	Ensembl

RefSeq Acc Id:

XM_005619990 ⟹ XP_005620047

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	5	32,574,153 - 32,586,222 (+)	NCBI
Dog10K_Boxer_Tasha	5	32,712,138 - 32,725,180 (+)	NCBI

Sequence:

show sequence

ATCCCAGCAACCCCCGCGAAGCTCCTGGCACAAAGCTGGACAGTCGCCATGACAAGTAAGGGCAAGCAGTTAGCCGGCGCGGGGAGGCGGTGGGGCTGGAGCCCGGGAGGAGGGCCGGGAGCCAGTCC
GGATTCTCACTGGGTTGGTGCTACAGCTACTTTACACTGGGGGTGGGGACGGTCGGCAGGCCGGAGCGGGGATGGCAGAATAAGTGGAAACCATTTTAGGAGACACCTGCTCCTGTGTCAGACATGAA
GGTGGGAGGGAGAGAGCTTTTGCACCTGTCATTCCCCTCCCGGATGGCTGGATATGCTCTTCTCATCAGCTAGAACGTCACCTTTTAGGAAAGACTTCCTTACTATCCGAATCCAACGAATTCCTTCA
GAGACCCTGTGTCACACCATCTTGTTTAATTTCCTTCGCAGCCCTTACCGTTTTCTGCAAAGATTTGTTCCTTGTCTTAGTAACACAGCAGCGTAAGCCATGGGGAGGGGGCGGGGGGGCAGAGACCT
TGTCAACTATCTTATTCATTGTATTTATTTCTCGGTGCCTAGTAGCACCTAGTAGCAAGGAAGAGCTCAGTAATAAATGCTTATTGAATGAATGAAAAGAGACGGAAGTCTGAGGAATTTGGCGGAAT
GAGAAGCAAAAAAAGGTCAAAAGCTGTAAAATCAAACATAGCGCCAGCGCCCTCCGCAGGTGAGGGTGGGTAGTAGGTGCTTTAGGAGTGCCGGAGGGAGACGGCAGGGGGAGCTCAGGCACTGCTCG
CCGAGGCAGAGGCTCTCGGACTACAACACCCAGCAACCACCACGAACCCTACGGCTTGATGGGAACGGTAAGCCTCCGCGACCTGTCACGTGCTTGCCCCGCCCCTCCCGCGAAATCTGACCCGGGAT
GCGGAGGTCCAATGGAAAGGCGGGGCCAAATCCCGCGAGAGCAAGTGGCTCTTAGTGACCGCGGGGGCTGAGGGACGCTGTGCTTGCGGCGGGGCGCGTCCACCGGTCCCGCTCGCCTTCCGGGGTCT
TCCGCCCTCTCCCGGAAGAAGGAGGAAGGGCCCCGGACGGGTTTTCCGGGGCTGCGTCCGGGAGCCGAGAAGTTTGAGGCGGTGTGGGCTGTCGTATCGGCAGGGCAGCTGGGCGCTCGAGGGACGAG
GGTCGCGGCGGGGGCCGGAGTCCGCGCTTCTTCGGCAGCATGAGCGCGCCCGAGGCGCCCCGGTCGGCCCCGGACTGCCTTGCTGCGGACCAGGCCCCCGCTCCGGCTCCCCTATCTCCTCGGGCTTC
CCCGACGGGTGAGAGTCCGGACTCTGAACTGTTGCCACCGCCGGTACCTCCCGCTGGGGACGGCCCGGCCCGCTCGTTCCCGGATCCCGCGGCGGGCTCCCGGGCGCCAGGGGAGGGCGGCCCCGTTT
CTGCCTCCACCGCCCTGCAGGCGGGCTTCTCTGCTCCTACCGACTTGAGCCCTCGAATTGAGGAGCCAGAGGTTGGTGAAAACGTGAGCCTTCCCGCAGAAGAAGCGGACGGGCCGGAATTGGGGCCA
GGAGAGGCGGTGGAAGGAGTGTCTGAGGACCTCGCCCCGGAGGACGAAGGATACAGCACCCGGAACTACTGCTTCTCCCAGCTCCCTCGGTTTCTCAGTGGTTCCTGGTCAGAGTTCACCCAACCCGA
GAACTTCTTGAAAGGCTGTAAGTGGGCTCCTGATGGTTCCTGCATCTTGACCAATAGTGCGGATAACATCCTGCGGATTTATAACCTGCCCCCAGAGCTGTACAATGAGGGGGAACAGGTGGAATATG
CAGAGATGGTCCCTGTCCTTCGAATGGTGGAAGGTGACACCATCTATGATTATTGTTGGTATTCTCTGATGTCTTCATCCGAGCCAGACACCTCCTACGTGGCCAGCAGCAGCCGGGAGAACCCCATT
CACATCTGGGATGCATTTACTGGAGAGCTCCGGGCTTCCTTTCGTGCCTACAACCACCTGGACGAGCTGACGGCAGCCCACTCGCTCTGCTTCTCCCCTGACGGCTCCCAGCTCTTCTGTGGCTTCAA
CAGGACCATACGGGTCTTTTCCACGGCCCGGCCTGGCCGTGACTGTGAGGTCCGAGCCACGTTTGCCAAAAAGCAGGGCCAGAGTGGCATCATCTCCTGCATAGCCTTCAGCCCAGCCCAACCCCTCT
ACGCTTGTGGCTCCTATAGCCGTTCCCTGGGTCTGTATGCCTGTGATGATGGCTCCCCTCTTGCTTTGCTGGGAGGACACCAAGGAGGCATCACTCACCTCTGCTTTCACCCTGATGGCAACCGCTTC
TTCTCAGGAGCCCGCAAGGATGCTGAGCTTCTGTGCTGGGACCTCCGGCAGCCCAGCCATCCACTGTGGTCGCTGAGTCGAGAGGTGACCACCAATCAGCGCATCTACTTCGATCTGGATTCGACTGG
GCAGTTCTTGGTGAGCGGGAGCACCAGTGGGGCTGTGTCTGTGTGGGACACCGGCGGGGCTGGACAGGAAGGGAAGCCGGAGCCGTTGCTGAGTTTTCTGCCCCAGAAAGACTGTACCAACGGAGTGA
GTCTGCACCCTAGCCTGCCATTGCTGGCCACCGCCTCCGGTCAGCGTGTGTTCCCAGAGCCCACAGAGAGTGAGGACGAAGGGGAGCGGGAGGTGGACCTTCCCCTGCTTTCCATGCGCCACGTCCAC
CTCGAATGTCAGCTTCAGCTCTGGTGGTGTGGTGGGNGACATGGAACCAGGATAGCTGATGCTCCCCAGGGCCAGAAGGGCCAGGGAGGGACTGAGGAAAGTGAGTGTGAGTTTACATAAAACCGTTT
TCTATGGCTCTA

hide sequence

RefSeq Acc Id:

XM_038475553 ⟹ XP_038331481

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	5	32,645,668 - 32,658,710 (+)	NCBI

RefSeq Acc Id:

XM_038536723 ⟹ XP_038392651

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	5	32,780,842 - 32,793,885 (+)	NCBI

RefSeq Acc Id:

XM_038600897 ⟹ XP_038456825

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	5	32,601,891 - 32,614,933 (+)	NCBI

RefSeq Acc Id:

XM_038665443 ⟹ XP_038521371

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	5	32,677,789 - 32,690,832 (+)	NCBI


Protein RefSeqs	XP_005620047	(Get FASTA)	NCBI Sequence Viewer
	XP_038331481	(Get FASTA)	NCBI Sequence Viewer
	XP_038392651	(Get FASTA)	NCBI Sequence Viewer
	XP_038456825	(Get FASTA)	NCBI Sequence Viewer
	XP_038521371	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000024592.5
	ENSCAFP00040010413.1
	ENSCAFP00845034349
	ENSCAFP00845034349.1

RefSeq Acc Id:

XP_005620047 ⟸ XM_005619990

- UniProtKB:

A0A8C0QER0 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSAPEAPRSAPDCLAADQAPAPAPLSPRASPTGESPDSELLPPPVPPAGDGPARSFPDPAAGSRAPGEGGPVSASTALQAGFSAPTDLSPRIEEPEVGENVSLPAEEADGPELGPGEAVEGVSEDLAP
EDEGYSTRNYCFSQLPRFLSGSWSEFTQPENFLKGCKWAPDGSCILTNSADNILRIYNLPPELYNEGEQVEYAEMVPVLRMVEGDTIYDYCWYSLMSSSEPDTSYVASSSRENPIHIWDAFTGELRAS
FRAYNHLDELTAAHSLCFSPDGSQLFCGFNRTIRVFSTARPGRDCEVRATFAKKQGQSGIISCIAFSPAQPLYACGSYSRSLGLYACDDGSPLALLGGHQGGITHLCFHPDGNRFFSGARKDAELLCW
DLRQPSHPLWSLSREVTTNQRIYFDLDSTGQFLVSGSTSGAVSVWDTGGAGQEGKPEPLLSFLPQKDCTNGVSLHPSLPLLATASGQRVFPEPTESEDEGEREVDLPLLSMRHVHLECQLQLWWCGGX
HGTRIADAPQGQKGQGGTEESECEFT

hide sequence

Ensembl Acc Id:

ENSCAFP00000053849 ⟸ ENSCAFT00000069246

Ensembl Acc Id:

ENSCAFP00000036919 ⟸ ENSCAFT00000045758

Ensembl Acc Id:

ENSCAFP00000057757 ⟸ ENSCAFT00000073485

Ensembl Acc Id:

ENSCAFP00000035853 ⟸ ENSCAFT00000042891

RGD ID:

13683236

Promoter ID:

EPDNEW_C1304

Type:

single initiation site

Name:

WRAP53_1

Description:

WD repeat containing antisense to TP53

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	5	32,575,373 - 32,575,433	EPDNEW

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000031192	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00040006355	UniProtKB/TrEMBL
	ENSCAFG00845024805	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000026478.6	UniProtKB/TrEMBL
	ENSCAFT00040012016.1	UniProtKB/TrEMBL
	ENSCAFT00845043832	ENTREZGENE
	ENSCAFT00845043832.1	UniProtKB/TrEMBL
Gene3D-CATH	2.130.10.10	UniProtKB/TrEMBL
InterPro	SWT21/TCAB1_mRNA_Telomere	UniProtKB/TrEMBL
	WD40/YVTN_repeat-like_dom_sf	UniProtKB/TrEMBL
	WD40_repeat	UniProtKB/TrEMBL
	WD40_repeat_dom_sf	UniProtKB/TrEMBL
NCBI Gene	WRAP53	ENTREZGENE
PANTHER	TELOMERASE CAJAL BODY PROTEIN 1	UniProtKB/TrEMBL
	UNCHARACTERIZED	UniProtKB/TrEMBL
Pfam	WD40	UniProtKB/TrEMBL
PROSITE	WD_REPEATS_2	UniProtKB/TrEMBL
SMART	WD40	UniProtKB/TrEMBL
Superfamily-SCOP	SSF50978	UniProtKB/TrEMBL
UniProt	A0A8C0QER0	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3PST8_CANLF	UniProtKB/TrEMBL
	A0A8P0NI36_CANLF	UniProtKB/TrEMBL
VGNC ID	VGNC:48432	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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