Wrap53 (WD repeat containing, antisense to Trp53) - Rat Genome Database

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Gene: Wrap53 (WD repeat containing, antisense to Trp53) Mus musculus
Analyze
Symbol: Wrap53
Name: WD repeat containing, antisense to Trp53
RGD ID: 1558239
MGI Page MGI
Description: Predicted to enable several functions, including identical protein binding activity; telomerase RNA binding activity; and ubiquitin protein ligase binding activity. Predicted to be involved in several processes, including RNA localization to Cajal body; positive regulation of double-strand break repair; and telomere organization. Predicted to act upstream of or within DNA repair. Predicted to be located in cytosol; nuclear body; and site of double-strand break. Predicted to be part of telomerase holoenzyme complex. Predicted to be active in Cajal body. Is expressed in palatal shelf. Human ortholog(s) of this gene implicated in autosomal recessive dyskeratosis congenita 3; colorectal cancer; head and neck squamous cell carcinoma; lung non-small cell carcinoma; and ovarian cancer. Orthologous to human WRAP53 (WD repeat containing antisense to TP53).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: BC021790; MGC28622; RP23-56I20.3; telomerase Cajal body protein 1; WD repeat containing, antisense to TP53; WD repeat domain 79; WD repeat-containing protein 79; WD repeat-containing protein WRAP53; WD40 repeat-containing protein antisense to TP53; WD40 repeat-containing protein antisense to TP53 gene homolog; WD40 repeat-containing protein encoded by RNA antisense to p53; Wdr7; Wdr79
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391169,452,580 - 69,471,076 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1169,452,584 - 69,471,081 (-)EnsemblGRCm39 Ensembl
GRCm381169,561,754 - 69,580,250 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1169,561,758 - 69,580,255 (-)EnsemblGRCm38mm10GRCm38
MGSCv371169,375,256 - 69,392,826 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361169,377,949 - 69,395,519 (-)NCBIMGSCv36mm8
Celera1176,524,707 - 76,542,284 (-)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1142.81NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. Nuclear expression of WRAP53β is associated with a positive response to radiotherapy and improved overall survival in patients with head and neck squamous cell carcinoma. Garvin S, etal., Oral Oncol. 2015 Jan;51(1):24-30. doi: 10.1016/j.oraloncology.2014.10.003. Epub 2014 Oct 27.
2. Downregulation of the cancer susceptibility protein WRAP53beta in epithelial ovarian cancer leads to defective DNA repair and poor clinical outcome. Hedstrom E, etal., Cell Death Dis. 2015 Oct 1;6:e1892. doi: 10.1038/cddis.2015.250.
3. Investigation of long noncoding RNAs expression profile as potential serum biomarkers in patients with hepatocellular carcinoma. Kamel MM, etal., Transl Res. 2016 Feb;168:134-45. doi: 10.1016/j.trsl.2015.10.002. Epub 2015 Oct 24.
4. Promoter methylation of Wrap53α, an antisense transcript of p53, is associated with the poor prognosis of patients with non-small cell lung cancer. Kim DS, etal., Oncol Lett. 2018 Nov;16(5):5823-5828. doi: 10.3892/ol.2018.9404. Epub 2018 Sep 5.
5. Association of common WRAP 53 variant with ovarian cancer risk in the Polish population. Mędrek K, etal., Mol Biol Rep. 2013 Mar;40(3):2145-7. doi: 10.1007/s11033-012-2273-9. Epub 2012 Nov 29.
6. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. Expression of WDR79 is associated with TP53 mutation and poor prognosis in surgically resected non-small cell lung cancer. Peng J, etal., J Cancer. 2019 Jun 2;10(13):3046-3053. doi: 10.7150/jca.30587. eCollection 2019.
9. Overexpression of WRAP53 is associated with development and progression of esophageal squamous cell carcinoma. Rao X, etal., PLoS One. 2014 Mar 13;9(3):e91670. doi: 10.1371/journal.pone.0091670. eCollection 2014.
10. Mouse MP Annotation Import Pipeline RGD automated import pipeline
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Single-strand conformational polymorphism analysis of a common single nucleotide variation in WRAP53 gene, rs2287499, and evaluating its association in relation to breast cancer risk and prognosis among Iranian-Azeri population. Sedaie Bonab A, etal., Med Oncol. 2014 Sep;31(9):168. doi: 10.1007/s12032-014-0168-4. Epub 2014 Aug 19.
14. The Sub-Cellular Localization of WRAP53 Has Prognostic Impact in Breast Cancer. Silwal-Pandit L, etal., PLoS One. 2015 Oct 13;10(10):e0139965. doi: 10.1371/journal.pone.0139965. eCollection 2015.
15. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
16. TCAB1: a potential target for diagnosis and therapy of head and neck carcinomas. Sun CK, etal., Mol Cancer. 2014 Jul 28;13:180. doi: 10.1186/1476-4598-13-180.
17. WRAP53β, survivin and p16INK4a expression as potential predictors of radiotherapy/chemoradiotherapy response in T2N0-T3N0 glottic laryngeal cancer. Tiefenböck-Hansson K, etal., Oncol Rep. 2017 Oct;38(4):2062-2068. doi: 10.3892/or.2017.5898. Epub 2017 Aug 11.
18. Epstein-Barr virus-induced up-regulation of TCAB1 is involved in the DNA damage response in nasopharyngeal carcinoma. Wang K, etal., Sci Rep. 2017 Jun 12;7(1):3218. doi: 10.1038/s41598-017-03156-3.
19. The prognostic factors and multiple biomarkers in young patients with colorectal cancer. Wang MJ, etal., Sci Rep. 2015 May 27;5:10645. doi: 10.1038/srep10645.
20. Clinical, cellular, and bioinformatic analyses reveal involvement of WRAP53 overexpression in carcinogenesis of lung adenocarcinoma. Yuan XS, etal., Tumour Biol. 2017 Mar;39(3):1010428317694309. doi: 10.1177/1010428317694309.
21. WRAP53 is an independent prognostic factor in rectal cancer- a study of Swedish clinical trial of preoperative radiotherapy in rectal cancer patients. Zhang H, etal., BMC Cancer. 2012 Jul 17;12:294. doi: 10.1186/1471-2407-12-294.
22. Disruption of telomerase trafficking by TCAB1 mutation causes dyskeratosis congenita. Zhong F, etal., Genes Dev. 2011 Jan 1;25(1):11-6. doi: 10.1101/gad.2006411.
23. Oncogenic Activity of Wrap53 in Human Colorectal Cancer In Vitro and in Nude Mouse Xenografts. Zhu Y, etal., Med Sci Monit. 2018 Sep 3;24:6129-6136. doi: 10.12659/MSM.910214.
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12520002   PMID:14610273   PMID:15489334   PMID:16141072   PMID:16141073   PMID:17967808  
PMID:18799693   PMID:19250907   PMID:21267068   PMID:21677750   PMID:21873635   PMID:26849396   PMID:27626380   PMID:29078390   PMID:29539633   PMID:29804836   PMID:30973865   PMID:35212626  


Genomics

Comparative Map Data
Wrap53
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391169,452,580 - 69,471,076 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1169,452,584 - 69,471,081 (-)EnsemblGRCm39 Ensembl
GRCm381169,561,754 - 69,580,250 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1169,561,758 - 69,580,255 (-)EnsemblGRCm38mm10GRCm38
MGSCv371169,375,256 - 69,392,826 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361169,377,949 - 69,395,519 (-)NCBIMGSCv36mm8
Celera1176,524,707 - 76,542,284 (-)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1142.81NCBI
WRAP53
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38177,686,071 - 7,703,502 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl177,686,071 - 7,703,502 (+)EnsemblGRCh38hg38GRCh38
GRCh37177,589,389 - 7,606,820 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36177,532,520 - 7,547,544 (+)NCBINCBI36Build 36hg18NCBI36
Celera177,615,750 - 7,633,180 (+)NCBICelera
Cytogenetic Map17p13.1NCBI
HuRef177,482,804 - 7,500,156 (+)NCBIHuRef
CHM1_1177,598,524 - 7,615,973 (+)NCBICHM1_1
T2T-CHM13v2.0177,590,175 - 7,607,622 (+)NCBIT2T-CHM13v2.0
Wrap53
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81054,780,873 - 54,797,919 (-)NCBIGRCr8
mRatBN7.21054,282,092 - 54,299,908 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1054,282,105 - 54,298,929 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1058,944,501 - 58,961,275 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01058,433,045 - 58,449,818 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01053,940,731 - 53,957,518 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01056,169,024 - 56,185,800 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1056,169,025 - 56,185,857 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01055,914,380 - 55,931,438 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41056,380,914 - 56,398,501 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11056,394,537 - 56,412,124 (-)NCBI
Celera1053,436,325 - 53,453,155 (-)NCBICelera
Cytogenetic Map10q24NCBI
Wrap53
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554679,225,506 - 9,240,756 (-)NCBIChiLan1.0ChiLan1.0
WRAP53
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21915,280,889 - 15,298,965 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11717,246,094 - 17,265,011 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0177,715,897 - 7,735,873 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1177,707,220 - 7,723,410 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl177,707,221 - 7,723,394 (+)Ensemblpanpan1.1panPan2
WRAP53
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1532,574,153 - 32,586,222 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl532,574,134 - 32,594,333 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha532,712,138 - 32,725,180 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0532,677,789 - 32,690,832 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl532,678,578 - 32,690,834 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1532,645,668 - 32,658,710 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0532,601,891 - 32,614,933 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0532,780,842 - 32,793,885 (+)NCBIUU_Cfam_GSD_1.0
Wrap53
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560247,461,298 - 47,478,596 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936595936,487 - 952,791 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936595936,184 - 952,784 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WRAP53
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1252,954,669 - 52,968,364 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11252,954,674 - 52,968,371 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21255,205,960 - 55,219,648 (-)NCBISscrofa10.2Sscrofa10.2susScr3
WRAP53
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1167,065,531 - 7,085,590 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl167,066,333 - 7,085,625 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605914,323,308 - 14,343,301 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Wrap53
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478610,283,984 - 10,296,729 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478610,283,721 - 10,296,568 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Wrap53
529 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:508
Count of miRNA genes:307
Interacting mature miRNAs:346
Transcripts:ENSMUST00000048139, ENSMUST00000132548, ENSMUST00000155894
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11325000072690826Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
1559002Lmrq4_mLeishmania major resistance QTL 4 (mouse)Not determined111226863769684947Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
1357782Char8_mP. chabaudi malaria resistance QTL 8 (mouse)Not determined113557861669684987Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113589082784890826Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113628257783481356Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113650328770509492Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113661356570613855Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113708094171081064Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113801611572016209Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114225661776256730Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114225661776256730Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114463003876854757Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114516587379978324Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114570858189818733Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114618516780185262Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114631940780319522Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115007819184078411Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115249438586494385Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115339058887390737Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115412675283733652Mouse
4141875Etax9_methanol induced ataxia 9 (mouse)Not determined5528498572209927Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115775466091754758Mouse
10053682Eae45_mexperimental allergic encephalomyelitis susceptibility 45 (mouse)Not determined115849055574754758Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15850803087695238Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5871926685066529Mouse
11532697Sluc36_msusceptibility to lung cancer 36 (mouse)115925661769482699Mouse
1301987Pid3_mprior incubation determinant 3 (mouse)Not determined116168682088699728Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116215600596156153Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162590826109390826Mouse
1301999Lmr15_mleishmaniasis resistance 15 (mouse)Not determined116331940781830473Mouse
10044004Stzid3_mstreptozotocin induced diabetes susceptibility 3 (mouse)Not determined116331940794063918Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116483033698830473Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116483033698830473Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116483033698830473Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166733420100733652Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166733420100733652Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166733420100733652Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166733420100733652Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66733420100733652Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166733420100733652Mouse
4142316Ity2b_mimmunity to S. typhimurium 2b (mouse)Not determined116707819179813912Mouse
27226783Tibl5_mtibia length 5, 5 week (mouse)1168190826101890826Mouse
36049778Ars6_mantibody response to SARS-CoV 6, day 15, IgM (mouse)116899082672490826Mouse
36049779Ars7_mantibody response to SARS-CoV 7, day 29, IgG1 (mouse)116899082672490826Mouse
36049784Ars8_mantibody response to SARS-CoV 8, day 29, IgG2a+IgG2c (mouse)116899082672490826Mouse
36049785Ars9_mantibody response to SARS-CoV 9, day 29, IgM (mouse)116899082672490826Mouse
36049786Ars10_mantibody response to SARS-CoV 10, 4 days post-rechallenge, IgG2a+IgG2c (mouse)116899082672490826Mouse
36049787Ars11_mantibody response to SARS-CoV 11, 4 days post-rechallenge, IgM (mouse)116899082672490826Mouse
36049788Ars1_mantibody response to SARS-CoV 1, day 7, IgG1 (mouse)116899082672490826Mouse
36049789Ars2_mantibody response to SARS-CoV 2, day 7, IgG2a+IgG2c (mouse)116899082672490826Mouse
36049790Ars3_mantibody response to SARS-CoV 3, day 7, IgG2b (mouse)116899082672490826Mouse
36049791Ars4_mantibody response to SARS-CoV 4, day 7, IgG3 (mouse)116899082672490826Mouse
36049792Ars5_mantibody response to SARS-CoV 5, day 7, IgM (mouse)116899082672490826Mouse
35673314Ari2_mantibody response to influenza 2, day 10, IgG3 (mouse)116899082672490826Mouse

Markers in Region
Trp53  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381169,580,069 - 69,580,174UniSTSGRCm38
MGSCv371169,393,571 - 69,393,676UniSTSGRCm37
Celera1176,543,029 - 76,543,134UniSTS
Cytogenetic Map11B2-CUniSTS
Cytogenetic Map11B3UniSTS
cM Map1139.0UniSTS


Expression


Sequence


RefSeq Acc Id: ENSMUST00000048139   ⟹   ENSMUSP00000047825
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1169,452,585 - 69,470,150 (-)Ensembl
GRCm38.p6 Ensembl1169,561,759 - 69,579,324 (-)Ensembl
RefSeq Acc Id: ENSMUST00000132548   ⟹   ENSMUSP00000121040
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1169,468,534 - 69,471,081 (-)Ensembl
GRCm38.p6 Ensembl1169,577,708 - 69,580,255 (-)Ensembl
RefSeq Acc Id: ENSMUST00000155894
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1169,452,584 - 69,454,748 (-)Ensembl
GRCm38.p6 Ensembl1169,561,758 - 69,563,922 (-)Ensembl
RefSeq Acc Id: NM_001364769   ⟹   NP_001351698
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391169,452,580 - 69,471,076 (-)NCBI
GRCm381169,561,754 - 69,580,250 (-)NCBI
Sequence:
RefSeq Acc Id: NM_144824   ⟹   NP_659073
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391169,452,580 - 69,470,075 (-)NCBI
GRCm381169,561,754 - 69,579,249 (-)NCBI
MGSCv371169,375,256 - 69,392,826 (-)RGD
Celera1176,524,707 - 76,542,284 (-)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006532899   ⟹   XP_006532962
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391169,454,169 - 69,471,071 (-)NCBI
GRCm381169,563,343 - 69,580,007 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006532900   ⟹   XP_006532963
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391169,454,222 - 69,471,071 (-)NCBI
GRCm381169,563,396 - 69,580,007 (-)NCBI
Sequence:
RefSeq Acc Id: XR_388402
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391169,452,587 - 69,471,071 (-)NCBI
GRCm381169,561,762 - 69,580,007 (-)NCBI
Sequence:
RefSeq Acc Id: NP_659073   ⟸   NM_144824
- UniProtKB: Q8VC51 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006532962   ⟸   XM_006532899
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006532963   ⟸   XM_006532900
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: NP_001351698   ⟸   NM_001364769
- UniProtKB: Q8VC51 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: ENSMUSP00000121040   ⟸   ENSMUST00000132548
RefSeq Acc Id: ENSMUSP00000047825   ⟸   ENSMUST00000048139

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8VC51-F1-model_v2 AlphaFold Q8VC51 1-532 view protein structure

Promoters
RGD ID:6822465
Promoter ID:MM_KWN:8078
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_144824
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361169,392,496 - 69,392,996 (-)MPROMDB
RGD ID:6822514
Promoter ID:MM_KWN:8079
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_001127233,   NM_011640,   OTTMUST00000013381,   OTTMUST00000013385,   UC007JQK.1,   UC007JQL.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361169,392,856 - 69,393,982 (-)MPROMDB
RGD ID:8675234
Promoter ID:EPDNEW_M15622
Type:initiation region
Name:Wrap53_1
Description:Mus musculus WD repeat containing, antisense to Trp53 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381169,579,249 - 69,579,309EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2384933 AgrOrtholog
Ensembl Genes ENSMUSG00000041346 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000048139 ENTREZGENE
  ENSMUST00000048139.12 UniProtKB/Swiss-Prot
  ENSMUST00000132548.2 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/Swiss-Prot
InterPro WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot
  WD40_repeat UniProtKB/Swiss-Prot
  WD40_repeat_dom_sf UniProtKB/Swiss-Prot
KEGG Report mmu:216853 UniProtKB/Swiss-Prot
MGD MGI:2384933 ENTREZGENE
NCBI Gene 216853 ENTREZGENE
PANTHER TELOMERASE CAJAL BODY PROTEIN 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UNCHARACTERIZED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam WD40 UniProtKB/Swiss-Prot
PhenoGen Wrap53 PhenoGen
PROSITE WD_REPEATS_REGION UniProtKB/Swiss-Prot
SMART WD40 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF50978 UniProtKB/Swiss-Prot
UniProt I7HJ86_MOUSE UniProtKB/TrEMBL
  Q8VC51 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-08-06 Wrap53  WD repeat containing, antisense to Trp53    WD repeat containing, antisense to TP53  Symbol and/or name change 5135510 APPROVED