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Gene: ANAPC2 (anaphase promoting complex subunit 2) Canis lupus familiaris

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Symbol:

ANAPC2

Name:

anaphase promoting complex subunit 2

RGD ID:

12160457

Description:

ENCODES a protein that exhibits ubiquitin protein ligase binding (inferred); INVOLVED IN negative regulation of gene expression (ortholog); positive regulation of axon extension (ortholog); positive regulation of dendrite morphogenesis (ortholog); ASSOCIATED WITH acute myeloid leukemia (ortholog); Adams-Oliver Syndrome 5 (ortholog); aplastic anemia (ortholog); FOUND IN anaphase-promoting complex (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

anaphase-promoting complex subunit 2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	48,475,777 - 48,486,715 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	48,471,584 - 48,609,303 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	47,666,446 - 47,677,538 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	49,341,288 - 49,352,382 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	49,341,432 - 49,355,653 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	48,117,700 - 48,128,794 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	48,416,513 - 48,427,605 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	48,463,672 - 48,474,764 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
ANAPC2	Dog	acute myeloid leukemia		ISO	ANAPC2 (Homo sapiens)	9068941	mRNA:increased expression:blood (human)	RGD	PMID:26046517 and REF_RGD_ID:11067888
ANAPC2	Dog	aplastic anemia		ISO	ANAPC2 (Homo sapiens)	9068941	protein:decreased expression:bone marrow (human)	RGD	PMID:28968996 and REF_RGD_ID:14696669
ANAPC2	Dog	Fetal Growth Retardation		ISO	ANAPC2 (Homo sapiens)	9068941	protein:increased expression:serum (human)	RGD	PMID:25724728 and REF_RGD_ID:14696679
ANAPC2	Dog	lung adenocarcinoma	severity	ISO	ANAPC2 (Homo sapiens)	9068941	mRNA:decreased expression:lung (human)	RGD	PMID:12036940 and REF_RGD_ID:14696682
ANAPC2	Dog	lung adenoma		ISO	ANAPC2 (Homo sapiens)	9068941	mRNA:decreased expression:lung (human)	RGD	PMID:14647414 and REF_RGD_ID:10047051
ANAPC2	Dog	Memory Disorders		ISO	Anapc2 (Mus musculus)	9068941		RGD	PMID:21191042 and REF_RGD_ID:14696672
ANAPC2	Dog	primary angle-closure glaucoma		ISO	ANAPC2 (Homo sapiens)	9068941	protein:increased expression:aqueous humor of eyeball (human)	RGD	PMID:29332228 and REF_RGD_ID:14696671
ANAPC2	Dog	Sotos syndrome 3		ISO	Anapc2 (Mus musculus)	9068941		RGD	PMID:25753423 and REF_RGD_ID:11055469

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
ANAPC2	Dog	Adams-Oliver Syndrome 5		ISO	ANAPC2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Adams-Oliver syndrome 5	ClinVar	PMID:16025100 more ...
ANAPC2	Dog	autosomal dominant intellectual developmental disorder 8		ISO	ANAPC2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Neurodevelopmental disorder with or without hyperkinetic movements and seizures and autosomal dominant	ClinVar	PMID:16826528 more ...
ANAPC2	Dog	developmental and epileptic encephalopathy 14		ISO	ANAPC2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Developmental and epileptic encephalopathy and 14	ClinVar	PMID:16025100 more ...
ANAPC2	Dog	epilepsy		ISO	ANAPC2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Epilepsy	ClinVar
ANAPC2	Dog	Joubert syndrome 1		ISO	ANAPC2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Familial aplasia of the vermis	ClinVar	PMID:16025100 more ...
ANAPC2	Dog	Kleefstra syndrome 1		ISO	ANAPC2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Kleefstra syndrome 1	ClinVar	PMID:16826528 more ...
ANAPC2	Dog	primary coenzyme Q10 deficiency 7		ISO	ANAPC2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Neonatal encephalomyopathy-cardiomyopathy-respiratory distress syndrome	ClinVar	PMID:28492532
ANAPC2	Dog	Rafiq syndrome		ISO	ANAPC2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Rafiq syndrome	ClinVar	PMID:24566669 more ...

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
ANAPC2	Dog	anaphase-promoting complex-dependent catabolic process	involved_in	IEA	UniProtKB:Q9UJX6 and ensembl:ENSP00000314004	150520179		Ensembl	GO_REF:0000107
ANAPC2	Dog	cell division	involved_in	IEA	UniProtKB-KW:KW-0132	150520179		UniProt	GO_REF:0000043
ANAPC2	Dog	metaphase/anaphase transition of mitotic cell cycle	involved_in	IBA	PANTHER:PTN000231994 and SGD:S000004117	150520179		GO_Central	GO_REF:0000033
ANAPC2	Dog	negative regulation of gene expression		ISO	Anapc2 (Rattus norvegicus)	9068941	Ppfia1	RGD	PMID:17419996 and REF_RGD_ID:14696670
ANAPC2	Dog	positive regulation of axon extension		ISO	Anapc2 (Rattus norvegicus)	9068941		RGD	PMID:19167333 and REF_RGD_ID:2306262
ANAPC2	Dog	positive regulation of dendrite morphogenesis		ISO	Anapc2 (Rattus norvegicus)	9068941		RGD	PMID:19167333 and REF_RGD_ID:2306262
ANAPC2	Dog	positive regulation of synapse maturation	involved_in	IEA	UniProtKB:Q8BZQ7 and ensembl:ENSMUSP00000028341	150520179		Ensembl	GO_REF:0000107
ANAPC2	Dog	positive regulation of synaptic plasticity	involved_in	IEA	UniProtKB:Q8BZQ7 and ensembl:ENSMUSP00000028341	150520179		Ensembl	GO_REF:0000107
ANAPC2	Dog	protein branched polyubiquitination	involved_in	IEA	UniProtKB:Q9UJX6 and ensembl:ENSP00000314004	150520179		Ensembl	GO_REF:0000107
ANAPC2	Dog	protein K11-linked ubiquitination	involved_in	IEA	UniProtKB:Q9UJX6 and ensembl:ENSP00000314004	150520179		Ensembl	GO_REF:0000107
ANAPC2	Dog	protein K11-linked ubiquitination	involved_in	IBA	PANTHER:PTN000231994 and UniProtKB:Q9UJX6	150520179		GO_Central	GO_REF:0000033
ANAPC2	Dog	protein K48-linked ubiquitination	involved_in	IEA	UniProtKB:Q9UJX6 and ensembl:ENSP00000314004	150520179		Ensembl	GO_REF:0000107
ANAPC2	Dog	protein ubiquitination	involved_in	IEA	UniPathway:UPA00143	150520179		UniProt	GO_REF:0000041
ANAPC2	Dog	ubiquitin-dependent protein catabolic process	involved_in	IEA	InterPro:IPR001373	150520179		InterPro	GO_REF:0000002

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
ANAPC2	Dog	anaphase-promoting complex	part_of	IEA	UniProtKB:Q9UJX6 and ensembl:ENSP00000314004	150520179		Ensembl	GO_REF:0000107
ANAPC2	Dog	anaphase-promoting complex	part_of	IBA	FB:FBgn0002791 more ...	150520179		GO_Central	GO_REF:0000033

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
ANAPC2	Dog	protein binding	enables	ISO	UniProtKB:Q4G163	9068941	PMID:34595750	UniProt	PMID:34595750
ANAPC2	Dog	protein binding	enables	ISO	UniProtKB:Q9UKT4-1	9068941	PMID:26083744	IntAct	PMID:26083744
ANAPC2	Dog	protein binding	enables	ISO	UniProtKB:P50221 and UniProtKB:P61964	9068941	PMID:32296183	IntAct	PMID:32296183
ANAPC2	Dog	protein binding	enables	ISO	UniProtKB:Q16763 more ...	9068941	PMID:23708001	UniProt	PMID:23708001
ANAPC2	Dog	protein binding	enables	ISO	UniProtKB:Q16763 and UniProtKB:Q9UKT4-1	9068941	PMID:23708001	IntAct	PMID:23708001
ANAPC2	Dog	ubiquitin protein ligase binding	enables	IEA	InterPro:IPR001373	150520179		InterPro	GO_REF:0000002

PMID:22301074	PMID:30032202

ANAPC2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	48,475,777 - 48,486,715 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	48,471,584 - 48,609,303 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	47,666,446 - 47,677,538 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	49,341,288 - 49,352,382 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	49,341,432 - 49,355,653 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	48,117,700 - 48,128,794 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	48,416,513 - 48,427,605 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	48,463,672 - 48,474,764 (+)	NCBI		UU_Cfam_GSD_1.0

ANAPC2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	137,174,784 - 137,188,560 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	137,174,784 - 137,188,560 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	9	140,069,236 - 140,083,012 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	139,189,057 - 139,202,878 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	9	137,345,072 - 137,358,894	NCBI
Celera	9	110,583,566 - 110,597,088 (-)	NCBI		Celera
Cytogenetic Map	9	q34.3	NCBI
HuRef	9	109,529,253 - 109,543,074 (-)	NCBI		HuRef
CHM1_1	9	140,217,925 - 140,231,746 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	9	149,412,464 - 149,426,223 (-)	NCBI		T2T-CHM13v2.0

Anapc2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	25,162,469 - 25,175,928 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	25,162,490 - 25,175,927 (+)	Ensembl		GRCm39 Ensembl
GRCm38	2	25,272,466 - 25,285,916 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	25,272,478 - 25,285,915 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	25,127,986 - 25,141,436 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	25,094,508 - 25,107,924 (+)	NCBI		MGSCv36	mm8
Celera	2	25,000,157 - 25,013,426 (+)	NCBI		Celera
Cytogenetic Map	2	A3	NCBI
cM Map	2	17.12	NCBI

Anapc2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	28,484,590 - 28,496,338 (+)	NCBI		GRCr8
mRatBN7.2	3	8,086,434 - 8,098,182 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	8,086,462 - 8,098,178 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	11,190,969 - 11,202,704 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	19,777,199 - 19,788,934 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	17,967,042 - 17,978,777 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	2,490,496 - 2,502,247 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	2,490,518 - 2,502,248 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	2,471,951 - 2,483,660 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	3,436,569 - 3,448,278 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	3,436,404 - 3,448,589 (+)	NCBI
Celera	3	2,913,015 - 2,924,724 (+)	NCBI		Celera
Cytogenetic Map	3	p13	NCBI

Anapc2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955513	5,183,472 - 5,194,253 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955513	5,183,472 - 5,194,253 (-)	NCBI	ChiLan1.0	ChiLan1.0

ANAPC2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	2,210,577 - 2,224,304 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	2,213,159 - 2,226,638 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	108,234,949 - 108,248,227 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	9	137,204,356 - 137,217,652 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	137,204,356 - 137,217,652 (-)	Ensembl	panpan1.1		panPan2

Anapc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	202,566,104 - 202,577,692 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936669	797,318 - 811,721 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936669	797,475 - 808,952 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ANAPC2
(Sus scrofa - pig)

No map positions available.

ANAPC2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	1,000,885 - 1,014,710 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	12	1,000,952 - 1,016,261 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666058	4,290,548 - 4,304,375 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Anapc2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624760	760,749 - 772,855 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624760	760,815 - 772,116 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in ANAPC2
81 total Variants

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
6	5	5	23	22	16	6	6	6	6	33	22	12	14	10


RefSeq Transcripts	XM_038486810	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038548680	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038612616	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038677901	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_548357	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000094	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000103	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000313	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00845043028 ⟹ ENSCAFP00845033736

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	9	49,341,432 - 49,355,565 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845043211 ⟹ ENSCAFP00845033876

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	9	49,354,597 - 49,355,653 (+)	Ensembl

RefSeq Acc Id:

XM_038486810 ⟹ XP_038342738

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	9	48,117,700 - 48,128,794 (+)	NCBI

RefSeq Acc Id:

XM_038548680 ⟹ XP_038404608

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	9	48,463,672 - 48,474,764 (+)	NCBI

RefSeq Acc Id:

XM_038612616 ⟹ XP_038468544

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	9	48,416,513 - 48,427,605 (+)	NCBI

RefSeq Acc Id:

XM_038677901 ⟹ XP_038533829

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	9	49,341,288 - 49,352,382 (+)	NCBI

RefSeq Acc Id:

XM_548357 ⟹ XP_548357

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	9	48,475,777 - 48,486,715 (+)	NCBI
Dog10K_Boxer_Tasha	9	47,666,446 - 47,677,538 (+)	NCBI

Sequence:

show sequence

GCTCGGGGGACCTGGAGGGGGCCGCGCAGATGGCGGCGGCGGGGCGCGACGGCGACCCCGGGCCCGCACAGGAGCTGTTGCTGGCCTGGAACACCGTGAGCACCGGGCTAGTGCCGCCGGCCGCGCTC
GGACTGGCGTCCTCCCGCACCAGCGGTGCGGTGCCGCCGAAGGAGGAGGAGCTCCGGGCGGCGGTGGAGGTGTTGAGGGGCCACGGCTTGCACTCGGTGCTGGAGGAGTGGTTTGTGGAGGTGCTGCA
GAACGACCTGCAGGCCCACATCTCGCTCGAGTTCTGGAATACCATCTCCCAGCGTGAGAACTGTGCGGACGAGCCCCAGTGCCTTCTGCTGCTCCTTGACGCCTTCGGCCTGCTGGAGAGTCGCCTGG
ACCCCTACCTGCGTAGCCTGGAGCTGCTGGAGAAGTGGACTCGCCTGGGCTTGCTGATGGGCGCAGGCGCTCAGGGGCTTCGGGAGAAAGTCCATACCACCTTGCGGGGCGTCCTGTTCTTTTCCACT
CCCAGAATGTTTCAGGAGATGATTCAGCGCCTCTACGGGCGGTTTTTGAGAGTCTACATGCAGAGTAAGAGGAAGGGGGAAGGGGGCACAGACCCGGAACTAGAGGGGGAGTTGGACAGCAGGTACGC
CCGCCGGCGGTACTACAGACTTCTGCAGAGCCCCCTGTGTGCGGGGTGTGGCAGTGACAAACAGCAATGCTGGTGCCGCCAGGCCCTGGAGCAGTTTCACCAGCTCAGCCAGGTCCTACACAGGCTCA
GTCTGTTGGAGCGGGTCAGTGCCGAGGCTGTGACCACCACCCTGCACCAGGTGACCAGGGAGAGGATGGAGGACCGCTGCCGGGGCGAGTATGAGCGCTCCTTCCTGCGTGAGTTCCACAAGTGGATC
GAGAGGGTGGTCGGCTGGCTGGGCAAGGTATTCCTGCAGGATGGCCCAGCCAGGCCTGCATCCCCTGAGGCTGGCAACACACTCCGTCGCTGGCGCTGCCACGTGCAAAGGTTCTTCTACCGTATCTA
TGCCAGCCTACGCATCGAGGAGCTCTTCAGCATCATCCGAGACTTCCCAGACTCCCGGCCAGCCATTGAGGACCTTAAGTACTGCCTGGAGAGGACCGATCAGAGGCAGCAGCTGCTCCTGTCCCTTA
AGGCTGCCCTGGAGACACGGCTCCTCCATCCAGGTGTCAACACATGTGACATCATCACCCTCTACATATCTGCCATCAAGGCCCTGCGTGTGCTGGACCCTTCCATGGTTATCCTGGAGGTGGCTTGT
GAGCCCATTCGCCGCTACCTGAGGACACGGGAGGATACTGTGCGGCAGATTGTGGCTGGGCTGACAGGGGACTCGGACGGGACAGGGGACTTGGCTGTTGAGCTGTCCAAGACCGATCCGGCGAGCCT
GGAGACTGGTCAGGACAGCGAGGATGACTCTGGCGAGCCTGAGGACTGGGTCCCTGACCCCGTGGATGCCGATCCAGGGAAGTCCAGCTCCAAGCGGCGCTCCTCGGACATCATCAGTCTCCTGGTCA
GCATCTACGGCAGCAAGGATCTCTTTATCAACGAGTACCGCTCACTGCTGGCTGACCGCCTCCTGCACCAGTTCAGCTTCAGTCCTGAGCGGGAGATCCGCAACGTGGAACTGCTGAAGCTGCGCTTT
GGCGAGGCTCCGATGCACTTCTGCGAGGTCATGCTGAAGGACATGGCAGATTCCCGTCGCATCAATGCCAACATTCGTGAAGAGGATGAGAAGCGGCCCGCAGAGGAGCAGCCACCTTTTGGGGTCTA
TGCTGTCATCCTATCCAGTGAGTTCTGGCCCCCCTTCAAGGATGAGAAGCTGGAAGTCCCTGAGGACATCAGGGAGGCCCTTGAGGTCTACTGCAAGAAGTATGAGAAGCTGAAGGCGATGCGGACCC
TCAGTTGGAAGCATACTCTGGGCTTGGTGACCATGGATGTGGAGCTGGCTGACCGCACCCTGTCTGTAGCCGTGACTCCCGTGCAGGCGGTGGTCTTGCTATACTTCCAGGACCAAGCTACCTGGACC
TTGGAGGAGCTGAGCAAGGTGGTGAAGATGCCTGTGGCACTGCTGCGGCGGCGGATGTCCGTGTGGTTGCAGCAGGGCGTGCTGAGGGAGGAGCCTGCTGGGACCTTCTCTGTCGTTGAAGAGGAGCG
GCCCCAGGACCGAGACAGCATGGTGCTCATCGACAGCGACGAGGAGAGTGACTCCGGCATGGCTTCCCAGGCCGACCAGAAGGAGGAGGAGCTGCTGCTTTTTTGGACATACATCCAGGCCATGCTGA
CCAATCTGGAGAGCCTGTCGCTGGAGCGCATCTACAGCATGCTGCGCATGTTCGTGGTGACCGGCCCCGCACTGGCTGAGATCGATCTGCAGGAGCTTCAGGGCTTCCTGCAGAAGAAGGTGCGAGAC
CAGCAGCTCGTCTACTCAGCCGGCGTCTACCGCCTGCCCAAGAGCTGCAGCTGATGTGCCCACCGGGAAGATGGGTGGGTGGGTGCCCCTGCCCAGCCCCCAGAGTGCAGAGTAAAGCAAATGGTTCT
CTATC

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Protein RefSeqs	XP_038342738	(Get FASTA)	NCBI Sequence Viewer
	XP_038404608	(Get FASTA)	NCBI Sequence Viewer
	XP_038468544	(Get FASTA)	NCBI Sequence Viewer
	XP_038533829	(Get FASTA)	NCBI Sequence Viewer
	XP_548357	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000028810.5
	ENSCAFP00000059558.1
	ENSCAFP00000064969.2
	ENSCAFP00040018600.1
	ENSCAFP00040018875.1
	ENSCAFP00845033736
	ENSCAFP00845033736.1

RefSeq Acc Id:

XP_548357 ⟸ XM_548357

- UniProtKB:

A0A8P0P8M5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAAAGRDGDPGPAQELLLAWNTVSTGLVPPAALGLASSRTSGAVPPKEEELRAAVEVLRGHGLHSVLEEWFVEVLQNDLQAHISLEFWNTISQRENCADEPQCLLLLLDAFGLLESRLDPYLRSLELL
EKWTRLGLLMGAGAQGLREKVHTTLRGVLFFSTPRMFQEMIQRLYGRFLRVYMQSKRKGEGGTDPELEGELDSRYARRRYYRLLQSPLCAGCGSDKQQCWCRQALEQFHQLSQVLHRLSLLERVSAEA
VTTTLHQVTRERMEDRCRGEYERSFLREFHKWIERVVGWLGKVFLQDGPARPASPEAGNTLRRWRCHVQRFFYRIYASLRIEELFSIIRDFPDSRPAIEDLKYCLERTDQRQQLLLSLKAALETRLLH
PGVNTCDIITLYISAIKALRVLDPSMVILEVACEPIRRYLRTREDTVRQIVAGLTGDSDGTGDLAVELSKTDPASLETGQDSEDDSGEPEDWVPDPVDADPGKSSSKRRSSDIISLLVSIYGSKDLFI
NEYRSLLADRLLHQFSFSPEREIRNVELLKLRFGEAPMHFCEVMLKDMADSRRINANIREEDEKRPAEEQPPFGVYAVILSSEFWPPFKDEKLEVPEDIREALEVYCKKYEKLKAMRTLSWKHTLGLV
TMDVELADRTLSVAVTPVQAVVLLYFQDQATWTLEELSKVVKMPVALLRRRMSVWLQQGVLREEPAGTFSVVEEERPQDRDSMVLIDSDEESDSGMASQADQKEEELLLFWTYIQAMLTNLESLSLER
IYSMLRMFVVTGPALAEIDLQELQGFLQKKVRDQQLVYSAGVYRLPKSCS

hide sequence

RefSeq Acc Id:

XP_038342738 ⟸ XM_038486810

RefSeq Acc Id:

XP_038468544 ⟸ XM_038612616

RefSeq Acc Id:	XP_038533829 ⟸ XM_038677901
- UniProtKB:	A0A8P0P8M5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038404608 ⟸ XM_038548680
- UniProtKB:	A0A8P0P8M5 (UniProtKB/TrEMBL)

Protein Domains

Cullin family profile

RGD ID:

13684743

Promoter ID:

EPDNEW_C2811

Type:

initiation region

Name:

ANAPC2_1

Description:

anaphase promoting complex subunit 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	9	48,475,752 - 48,475,812	EPDNEW

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000019483	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00040011445	UniProtKB/TrEMBL
	ENSCAFG00845024357	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000030976.5	UniProtKB/TrEMBL
	ENSCAFT00000065235.2	UniProtKB/TrEMBL
	ENSCAFT00000088170.2	UniProtKB/TrEMBL
	ENSCAFT00040021415.1	UniProtKB/TrEMBL
	ENSCAFT00040021750.1	UniProtKB/TrEMBL
	ENSCAFT00845043028	ENTREZGENE
	ENSCAFT00845043028.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.10.10	UniProtKB/TrEMBL
	Cullin Repeats	UniProtKB/TrEMBL
	Cullin, Chain C, Domain 2	UniProtKB/TrEMBL
InterPro	APC2-like	UniProtKB/TrEMBL
	APC2_C	UniProtKB/TrEMBL
	Cullin_homology	UniProtKB/TrEMBL
	Cullin_homology_sf	UniProtKB/TrEMBL
	Cullin_N	UniProtKB/TrEMBL
	WH-like_DNA-bd_sf	UniProtKB/TrEMBL
	WH_DNA-bd_sf	UniProtKB/TrEMBL
NCBI Gene	ANAPC2	ENTREZGENE
PANTHER	ANAPHASE-PROMOTING COMPLEX SUBUNIT 2	UniProtKB/TrEMBL
	PTHR45957	UniProtKB/TrEMBL
Pfam	ANAPC2	UniProtKB/TrEMBL
	Cullin	UniProtKB/TrEMBL
PROSITE	CULLIN_2	UniProtKB/TrEMBL
SMART	APC2	UniProtKB/TrEMBL
	CULLIN	UniProtKB/TrEMBL
Superfamily-SCOP	SSF46785	UniProtKB/TrEMBL
	SSF75632	UniProtKB/TrEMBL
UniProt	A0A8C0SCF4_CANLF	UniProtKB/TrEMBL
	A0A8C0YW28_CANLF	UniProtKB/TrEMBL
	A0A8I3PLH7_CANLF	UniProtKB/TrEMBL
	A0A8P0P8M5	ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary	A0A8P0TGK8	UniProtKB/TrEMBL
VGNC ID	VGNC:37849	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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Imported Disease Annotations - ClinVar