BTK (Bruton tyrosine kinase) - Rat Genome Database

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Gene: BTK (Bruton tyrosine kinase) Canis lupus familiaris
Analyze
Symbol: BTK
Name: Bruton tyrosine kinase
RGD ID: 12283322
Description: ENCODES a protein that exhibits protein tyrosine kinase activity (ortholog); INVOLVED IN eosinophil homeostasis; monocyte proliferation; negative regulation of leukocyte proliferation; PARTICIPATES IN erythropoietin signaling pathway; FasL mediated signaling pathway; Fc epsilon receptor mediated signaling pathway; ASSOCIATED WITH Adenoviridae Infections (ortholog); agammaglobulinemia (ortholog); agammaglobulinemia 1 (ortholog); FOUND IN cytosol (ortholog); perinuclear region of cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: tyrosine-protein kinase BTK
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X75,270,952 - 75,302,663 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX75,270,979 - 75,302,562 (-)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.0X76,691,359 - 76,723,087 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX76,691,367 - 76,723,042 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X74,255,464 - 74,287,205 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X75,915,885 - 75,947,610 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X75,678,325 - 75,710,045 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adaptive immune response  (IEA)
B cell affinity maturation  (IEA,ISO)
B cell receptor signaling pathway  (IEA)
cell maturation  (IEA,ISO)
cellular response to interleukin-7  (IEA,ISO)
cellular response to molecule of fungal origin  (ISO)
cellular response to reactive oxygen species  (ISO)
eosinophil homeostasis  (IMP)
histamine secretion by mast cell  (ISO)
I-kappaB kinase/NF-kappaB signaling  (IEA,ISO)
intracellular signal transduction  (IEA)
monocyte proliferation  (IMP)
negative regulation of B cell activation  (ISO)
negative regulation of B cell proliferation  (IEA,ISO)
negative regulation of cytokine production  (IEA)
negative regulation of interleukin-10 production  (ISO)
negative regulation of leukocyte proliferation  (IMP)
neutrophil homeostasis  (IMP)
peptidyl-tyrosine autophosphorylation  (ISO)
peptidyl-tyrosine phosphorylation  (IEA,ISO)
phosphorylation  (IEA)
positive regulation of B cell proliferation  (ISO)
positive regulation of immunoglobulin production  (ISO)
positive regulation of inflammatory response  (ISO)
positive regulation of interleukin-17A production  (ISO)
positive regulation of interleukin-6 production  (ISO)
positive regulation of phagocytosis  (ISO)
positive regulation of synoviocyte proliferation  (ISO)
positive regulation of tumor necrosis factor production  (ISO)
positive regulation of type I hypersensitivity  (ISO)
positive regulation of type III hypersensitivity  (ISO)
protein autophosphorylation  (ISO)
protein phosphorylation  (IEA,ISO)
proteoglycan catabolic process  (ISO)
regulation of catalytic activity  (IEA)
response to lipopolysaccharide  (ISO)
response to organic substance  (ISO)

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Nonclinical Safety Assessment of Zanubrutinib: A Novel Irreversible BTK Inhibitor. Zhang C and Tian B, Int J Toxicol. 2020 May/Jun;39(3):232-240. doi: 10.1177/1091581820918511.

Genomics

Comparative Map Data
BTK
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X75,270,952 - 75,302,663 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX75,270,979 - 75,302,562 (-)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.0X76,691,359 - 76,723,087 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX76,691,367 - 76,723,042 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X74,255,464 - 74,287,205 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X75,915,885 - 75,947,610 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X75,678,325 - 75,710,045 (-)NCBIUU_Cfam_GSD_1.0
BTK
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X101,349,450 - 101,390,796 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 EnsemblX101,349,338 - 101,390,796 (-)EnsemblGRCh38hg38GRCh38
GRCh37X100,604,438 - 100,645,784 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X100,491,098 - 100,527,838 (-)NCBINCBI36Build 36hg18NCBI36
Build 34X100,410,586 - 100,447,327NCBI
CeleraX101,123,894 - 101,160,669 (-)NCBICelera
Cytogenetic MapXq22.1NCBI
HuRefX90,410,583 - 90,447,505 (-)NCBIHuRef
CHM1_1X100,497,918 - 100,534,692 (-)NCBICHM1_1
T2T-CHM13v2.0X99,793,571 - 99,834,908 (-)NCBIT2T-CHM13v2.0
Btk
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X133,443,083 - 133,484,366 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX133,443,085 - 133,484,319 (-)EnsemblGRCm39 Ensembl
GRCm38X134,542,334 - 134,583,628 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX134,542,336 - 134,583,570 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X131,076,880 - 131,117,679 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X129,888,761 - 129,929,466 (-)NCBIMGSCv36mm8
CeleraX117,421,885 - 117,462,725 (-)NCBICelera
Cytogenetic MapXE3NCBI
cM MapX56.18NCBI
Btk
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X97,722,796 - 97,762,315 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX97,722,802 - 97,761,853 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX99,397,016 - 99,436,088 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0X102,907,749 - 102,946,794 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0X100,410,180 - 100,449,237 (-)NCBIRnor_WKY
Rnor_6.0X105,360,922 - 105,390,580 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX105,360,922 - 105,390,580 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X105,250,666 - 105,279,934 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X121,998,935 - 122,030,289 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X122,072,367 - 122,103,722 (-)NCBI
CeleraX98,764,036 - 98,794,122 (-)NCBICelera
Cytogenetic MapXq32NCBI
Btk
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555037,482,793 - 7,515,120 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555037,483,819 - 7,515,085 (-)NCBIChiLan1.0ChiLan1.0
BTK
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1X100,684,017 - 100,720,868 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX100,684,017 - 100,725,187 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0X90,551,874 - 90,588,786 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
Btk
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X63,007,672 - 63,045,710 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936813429,400 - 467,481 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BTK
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX82,981,515 - 83,014,573 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X82,981,512 - 83,014,475 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
BTK
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X89,690,569 - 89,727,420 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366606514,609,796 - 14,647,019 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Btk
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249021,182,682 - 1,216,171 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249021,173,101 - 1,216,662 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 6 3
Low 5 21 6 6 6 11 7 6
Below cutoff 5 1 6 1 8

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005641566 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038450447 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038450448 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038450449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038450450 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038523903 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038523904 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038523905 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038523906 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038587868 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038587869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038587870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038587871 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038652392 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038652393 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038652394 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038652395 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_549139 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAAHUQ010000391 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000028042   ⟹   ENSCAFP00000026084
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 EnsemblX75,270,979 - 75,302,562 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000071272   ⟹   ENSCAFP00000051063
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 EnsemblX75,270,979 - 75,302,562 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000073717   ⟹   ENSCAFP00000045231
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 EnsemblX75,270,979 - 75,295,838 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000082561   ⟹   ENSCAFP00000062869
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 EnsemblX75,270,979 - 75,295,838 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000091535   ⟹   ENSCAFP00000043729
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 EnsemblX75,270,979 - 75,295,838 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000092204   ⟹   ENSCAFP00000046885
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 EnsemblX75,270,979 - 75,295,838 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845033479   ⟹   ENSCAFP00845026209
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 EnsemblX76,691,367 - 76,723,042 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845033615   ⟹   ENSCAFP00845026318
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 EnsemblX76,691,367 - 76,716,273 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845033797   ⟹   ENSCAFP00845026450
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 EnsemblX76,691,367 - 76,716,273 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845033949   ⟹   ENSCAFP00845026567
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 EnsemblX76,691,367 - 76,713,835 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845034064   ⟹   ENSCAFP00845026666
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 EnsemblX76,691,367 - 76,713,835 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845034204   ⟹   ENSCAFP00845026778
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 EnsemblX76,691,367 - 76,713,835 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845034332   ⟹   ENSCAFP00845026876
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 EnsemblX76,691,367 - 76,713,835 (-)Ensembl
RefSeq Acc Id: XM_038450447   ⟹   XP_038306375
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0X76,691,359 - 76,716,737 (-)NCBI
RefSeq Acc Id: XM_038450448   ⟹   XP_038306376
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0X76,691,359 - 76,723,087 (-)NCBI
RefSeq Acc Id: XM_038450449   ⟹   XP_038306377
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0X76,691,359 - 76,723,084 (-)NCBI
RefSeq Acc Id: XM_038450450   ⟹   XP_038306378
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0X76,691,359 - 76,723,080 (-)NCBI
RefSeq Acc Id: XM_038523903   ⟹   XP_038379831
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1X74,255,464 - 74,280,841 (-)NCBI
RefSeq Acc Id: XM_038523904   ⟹   XP_038379832
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1X74,255,464 - 74,287,205 (-)NCBI
RefSeq Acc Id: XM_038523905   ⟹   XP_038379833
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1X74,255,464 - 74,287,202 (-)NCBI
RefSeq Acc Id: XM_038523906   ⟹   XP_038379834
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1X74,255,464 - 74,287,198 (-)NCBI
RefSeq Acc Id: XM_038587868   ⟹   XP_038443796
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0X75,678,325 - 75,703,681 (-)NCBI
RefSeq Acc Id: XM_038587869   ⟹   XP_038443797
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0X75,678,325 - 75,710,045 (-)NCBI
RefSeq Acc Id: XM_038587870   ⟹   XP_038443798
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0X75,678,325 - 75,710,042 (-)NCBI
RefSeq Acc Id: XM_038587871   ⟹   XP_038443799
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0X75,678,325 - 75,710,038 (-)NCBI
RefSeq Acc Id: XM_038652392   ⟹   XP_038508320
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0X75,915,885 - 75,941,249 (-)NCBI
RefSeq Acc Id: XM_038652393   ⟹   XP_038508321
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0X75,915,885 - 75,947,610 (-)NCBI
RefSeq Acc Id: XM_038652394   ⟹   XP_038508322
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0X75,915,885 - 75,947,607 (-)NCBI
RefSeq Acc Id: XM_038652395   ⟹   XP_038508323
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0X75,915,885 - 75,947,603 (-)NCBI
Reference Sequences
RefSeq Acc Id: ENSCAFP00000026084   ⟸   ENSCAFT00000028042
RefSeq Acc Id: ENSCAFP00000045231   ⟸   ENSCAFT00000073717
RefSeq Acc Id: ENSCAFP00000043729   ⟸   ENSCAFT00000091535
RefSeq Acc Id: ENSCAFP00000062869   ⟸   ENSCAFT00000082561
RefSeq Acc Id: ENSCAFP00000046885   ⟸   ENSCAFT00000092204
RefSeq Acc Id: ENSCAFP00000051063   ⟸   ENSCAFT00000071272
RefSeq Acc Id: XP_038379832   ⟸   XM_038523904
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038379833   ⟸   XM_038523905
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038379834   ⟸   XM_038523906
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038379831   ⟸   XM_038523903
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038508321   ⟸   XM_038652393
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038508322   ⟸   XM_038652394
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038508323   ⟸   XM_038652395
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038508320   ⟸   XM_038652392
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038306376   ⟸   XM_038450448
- Peptide Label: isoform X2
- UniProtKB: A0A8C0SW87 (UniProtKB/TrEMBL),   E2RMF7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038306377   ⟸   XM_038450449
- Peptide Label: isoform X2
- UniProtKB: A0A8C0SW87 (UniProtKB/TrEMBL),   E2RMF7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038306378   ⟸   XM_038450450
- Peptide Label: isoform X2
- UniProtKB: A0A8C0SW87 (UniProtKB/TrEMBL),   E2RMF7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038306375   ⟸   XM_038450447
- Peptide Label: isoform X1
- UniProtKB: A0A8C0SX09 (UniProtKB/TrEMBL),   A0A5F4BPN2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038443797   ⟸   XM_038587869
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038443798   ⟸   XM_038587870
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038443799   ⟸   XM_038587871
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038443796   ⟸   XM_038587868
- Peptide Label: isoform X1
RefSeq Acc Id: ENSCAFP00845026666   ⟸   ENSCAFT00845034064
RefSeq Acc Id: ENSCAFP00845026778   ⟸   ENSCAFT00845034204
RefSeq Acc Id: ENSCAFP00845026318   ⟸   ENSCAFT00845033615
RefSeq Acc Id: ENSCAFP00845026567   ⟸   ENSCAFT00845033949
RefSeq Acc Id: ENSCAFP00845026209   ⟸   ENSCAFT00845033479
RefSeq Acc Id: ENSCAFP00845026876   ⟸   ENSCAFT00845034332
RefSeq Acc Id: ENSCAFP00845026450   ⟸   ENSCAFT00845033797
Protein Domains
PH   Protein kinase   SH2   SH3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000017669 Ensembl
  ENSCAFG00030007968 UniProtKB/TrEMBL
  ENSCAFG00040016606 UniProtKB/TrEMBL
  ENSCAFG00845018798 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00030013258.1 UniProtKB/TrEMBL
  ENSCAFP00030013380.1 UniProtKB/TrEMBL
  ENSCAFP00030013514.1 UniProtKB/TrEMBL
  ENSCAFP00030013647.1 UniProtKB/TrEMBL
  ENSCAFP00030013744.1 UniProtKB/TrEMBL
  ENSCAFP00030013873.1 UniProtKB/TrEMBL
  ENSCAFP00040027098 UniProtKB/TrEMBL
  ENSCAFP00040027219 UniProtKB/TrEMBL
  ENSCAFP00040027307 UniProtKB/TrEMBL
  ENSCAFP00040027435 UniProtKB/TrEMBL
  ENSCAFP00040027558 UniProtKB/TrEMBL
  ENSCAFP00845026209 ENTREZGENE
  ENSCAFP00845026209.1 UniProtKB/TrEMBL
  ENSCAFP00845026318 ENTREZGENE
  ENSCAFP00845026318.1 UniProtKB/TrEMBL
  ENSCAFP00845026450.1 UniProtKB/TrEMBL
  ENSCAFP00845026567.1 UniProtKB/TrEMBL
  ENSCAFP00845026666.1 UniProtKB/TrEMBL
  ENSCAFP00845026778.1 UniProtKB/TrEMBL
  ENSCAFP00845026876.1 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00030015201.1 UniProtKB/TrEMBL
  ENSCAFT00030015343.1 UniProtKB/TrEMBL
  ENSCAFT00030015503.1 UniProtKB/TrEMBL
  ENSCAFT00030015656.1 UniProtKB/TrEMBL
  ENSCAFT00030015762.1 UniProtKB/TrEMBL
  ENSCAFT00030015910.1 UniProtKB/TrEMBL
  ENSCAFT00040031173 UniProtKB/TrEMBL
  ENSCAFT00040031306 UniProtKB/TrEMBL
  ENSCAFT00040031401 UniProtKB/TrEMBL
  ENSCAFT00040031544 UniProtKB/TrEMBL
  ENSCAFT00040031696 UniProtKB/TrEMBL
  ENSCAFT00845033479 ENTREZGENE
  ENSCAFT00845033479.1 UniProtKB/TrEMBL
  ENSCAFT00845033615 ENTREZGENE
  ENSCAFT00845033615.1 UniProtKB/TrEMBL
  ENSCAFT00845033797.1 UniProtKB/TrEMBL
  ENSCAFT00845033949.1 UniProtKB/TrEMBL
  ENSCAFT00845034064.1 UniProtKB/TrEMBL
  ENSCAFT00845034204.1 UniProtKB/TrEMBL
  ENSCAFT00845034332.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
  3.30.505.10 UniProtKB/TrEMBL
InterPro BTK_SH3 UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  SH2_dom_sf UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
  Tyr_kinase_AS UniProtKB/TrEMBL
  Tyr_kinase_cat_dom UniProtKB/TrEMBL
  Znf_Btk_motif UniProtKB/TrEMBL
NCBI Gene BTK ENTREZGENE
Pfam BTK UniProtKB/TrEMBL
  PF00169 UniProtKB/TrEMBL
  PK_Tyr_Ser-Thr UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  SH3_1 UniProtKB/TrEMBL
PRINTS SH2DOMAIN UniProtKB/TrEMBL
  SH3DOMAIN UniProtKB/TrEMBL
  TECBTKDOMAIN UniProtKB/TrEMBL
  TYRKINASE UniProtKB/TrEMBL
PROSITE PH_DOMAIN UniProtKB/TrEMBL
  PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_TYR UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
  ZF_BTK UniProtKB/TrEMBL
SMART BTK UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
  TyrKc UniProtKB/TrEMBL
Superfamily-SCOP SSF50044 UniProtKB/TrEMBL
  SSF55550 UniProtKB/TrEMBL
  SSF56112 UniProtKB/TrEMBL
UniProt A0A5F4BPN2 ENTREZGENE
  A0A8C0MR79_CANLF UniProtKB/TrEMBL
  A0A8C0MRF7_CANLF UniProtKB/TrEMBL
  A0A8C0MRR6_CANLF UniProtKB/TrEMBL
  A0A8C0MUL8_CANLF UniProtKB/TrEMBL
  A0A8C0SW87 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0SX09 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0SXD7_CANLF UniProtKB/TrEMBL
  A0A8I3NXR3_CANLF UniProtKB/TrEMBL
  A0A8I3P3Z9_CANLF UniProtKB/TrEMBL
  A0A8I3P4H9_CANLF UniProtKB/TrEMBL
  A0A8I3P7Z3_CANLF UniProtKB/TrEMBL
  A0A8I3P900_CANLF UniProtKB/TrEMBL
  A0A8I3PFJ4_CANLF UniProtKB/TrEMBL
  A0A8I3PGX3_CANLF UniProtKB/TrEMBL
  E2RMF7 ENTREZGENE
VGNC ID VGNC:38560 ENTREZGENE