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G |
ABCB1 |
ATP binding cassette subfamily B member 1 |
multiple interactions increases activity |
EXP |
morin promotes the reaction [Quercetin results in increased activity of ABCB1 protein] morin results in increased activity of ABCB1 protein |
CTD |
PMID:34217736 |
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NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
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G |
ABCB11 |
ATP binding cassette subfamily B member 11 |
decreases activity multiple interactions |
EXP |
morin results in decreased activity of ABCB11 protein morin inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid] |
CTD |
PMID:24014644 |
|
NCBI chr 2:168,915,390...169,031,324
Ensembl chr 2:168,915,498...169,031,324
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G |
ABCC1 |
ATP binding cassette subfamily C member 1 (ABCC1 blood group) |
decreases activity |
EXP |
morin results in decreased activity of ABCC1 protein |
CTD |
PMID:15670588 |
|
NCBI chr16:15,949,143...16,143,053
Ensembl chr16:15,949,138...16,143,257
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G |
ACHE |
acetylcholinesterase (Yt blood group) |
multiple interactions |
ISO |
morin inhibits the reaction [Ifosfamide results in increased activity of ACHE protein] |
CTD |
PMID:31722249 |
|
NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974
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G |
ACTA2 |
actin alpha 2, smooth muscle |
multiple interactions |
ISO |
morin inhibits the reaction [Dimethylnitrosamine results in increased expression of ACTA2 mRNA]; morin inhibits the reaction [Dimethylnitrosamine results in increased expression of ACTA2 protein] |
CTD |
PMID:18629640 |
|
NCBI chr10:88,935,074...88,991,337
Ensembl chr10:88,935,074...88,991,339
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|
G |
ADIPOQ |
adiponectin, C1Q and collagen domain containing |
multiple interactions |
ISO |
morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein] |
CTD |
PMID:24854284 |
|
NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463
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G |
AHR |
aryl hydrocarbon receptor |
multiple interactions |
EXP |
AHR gene mutant form inhibits the reaction [morin results in increased expression of CYP1A1 mRNA]; AHR gene mutant form inhibits the reaction [morin results in increased expression of UGT1A1 mRNA] |
CTD |
PMID:29584932 |
|
NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152
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|
G |
AIFM1 |
apoptosis inducing factor mitochondria associated 1 |
multiple interactions |
ISO |
morin inhibits the reaction [Excitatory Amino Acid Agonists affects the localization of AIFM1 protein] |
CTD |
PMID:19201465 |
|
NCBI chr X:130,129,362...130,165,841
Ensembl chr X:130,124,666...130,165,879
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|
G |
AKT1 |
AKT serine/threonine kinase 1 |
multiple interactions increases expression |
ISO EXP |
morin inhibits the reaction [Acetaminophen results in decreased phosphorylation of AKT1 protein]; morin inhibits the reaction [Excitatory Amino Acid Agonists results in decreased phosphorylation of AKT1 protein]; morin inhibits the reaction [Streptozocin results in increased expression of AKT1 mRNA] morin results in increased expression of AKT1 mRNA |
CTD |
PMID:19201465 PMID:26767949 PMID:28689916 PMID:35414346 |
|
NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751
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G |
APAF1 |
apoptotic peptidase activating factor 1 |
increases expression |
EXP |
morin results in increased expression of APAF1 mRNA |
CTD |
PMID:28689916 |
|
NCBI chr12:98,645,290...98,735,433
Ensembl chr12:98,645,290...98,735,433
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|
G |
APP |
amyloid beta precursor protein |
multiple interactions |
EXP |
morin affects the reaction [APP protein binds to APP protein] |
CTD |
PMID:18537544 |
|
NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128
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|
G |
AQP2 |
aquaporin 2 |
multiple interactions |
ISO |
morin inhibits the reaction [Doxorubicin affects the expression of AQP2 protein] |
CTD |
PMID:31100273 |
|
NCBI chr12:49,950,737...49,958,878
Ensembl chr12:49,950,737...49,958,878
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|
G |
AR |
androgen receptor |
decreases expression multiple interactions |
EXP ISO |
morin results in decreased expression of AR mRNA morin inhibits the reaction [[bisphenol S co-treated with diethyl phthalate] results in increased expression of AR mRNA] |
CTD |
PMID:24726691 PMID:35900689 |
|
NCBI chr X:67,544,021...67,730,619
Ensembl chr X:67,544,021...67,730,619
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G |
BAX |
BCL2 associated X, apoptosis regulator |
multiple interactions increases expression |
ISO EXP |
morin inhibits the reaction [[bisphenol S co-treated with diethyl phthalate] results in increased expression of BAX mRNA]; morin inhibits the reaction [Acetaminophen results in increased expression of BAX protein]; morin inhibits the reaction [Diethylnitrosamine results in decreased expression of BAX protein]; morin inhibits the reaction [Doxorubicin affects the expression of BAX protein]; morin inhibits the reaction [Excitatory Amino Acid Agonists results in increased expression of BAX protein]; morin inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; morin inhibits the reaction [titanium dioxide results in increased expression of BAX mRNA] morin results in increased expression of BAX mRNA |
CTD |
PMID:19201465 PMID:19931519 PMID:26767949 PMID:28689916 PMID:28844848 PMID:31100273 PMID:35414346 PMID:35900689 More...
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|
NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
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G |
BCHE |
butyrylcholinesterase |
multiple interactions |
ISO |
morin inhibits the reaction [Ifosfamide results in increased activity of BCHE protein] |
CTD |
PMID:31722249 |
|
NCBI chr 3:165,772,904...165,837,423
Ensembl chr 3:165,772,904...165,837,462
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G |
BCL2 |
BCL2 apoptosis regulator |
multiple interactions decreases expression |
ISO EXP |
morin inhibits the reaction [Acetaminophen results in decreased expression of BCL2 protein]; morin inhibits the reaction [Diethylnitrosamine results in increased expression of BCL2 protein]; morin inhibits the reaction [Doxorubicin results in decreased expression of BCL2 protein]; morin inhibits the reaction [Ifosfamide results in decreased expression of BCL2 mRNA]; morin inhibits the reaction [Streptozocin results in increased expression of BCL2 mRNA]; morin inhibits the reaction [titanium dioxide results in decreased expression of BCL2 mRNA] morin results in decreased expression of BCL2 mRNA |
CTD |
PMID:19931519 PMID:26767949 PMID:28689916 PMID:28844848 PMID:31100273 PMID:31722249 PMID:35414346 More...
|
|
NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
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G |
BCL2L1 |
BCL2 like 1 |
decreases expression multiple interactions |
EXP ISO |
morin results in decreased expression of BCL2L1 mRNA morin inhibits the reaction [Streptozocin results in increased expression of BCL2L1 mRNA] |
CTD |
PMID:28689916 PMID:35414346 |
|
NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989
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G |
BDNF |
brain derived neurotrophic factor |
multiple interactions |
ISO |
morin inhibits the reaction [Ifosfamide results in increased expression of BDNF mRNA]; morin inhibits the reaction [Streptozocin results in increased expression of BDNF mRNA] |
CTD |
PMID:31722249 PMID:35414346 |
|
NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058
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|
G |
BIRC2 |
baculoviral IAP repeat containing 2 |
decreases expression |
EXP |
morin results in decreased expression of BIRC2 mRNA |
CTD |
PMID:28689916 |
|
NCBI chr11:102,347,214...102,378,670
Ensembl chr11:102,347,211...102,378,670
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G |
BIRC3 |
baculoviral IAP repeat containing 3 |
decreases expression |
EXP |
morin results in decreased expression of BIRC3 mRNA |
CTD |
PMID:28689916 |
|
NCBI chr11:102,317,484...102,339,403
Ensembl chr11:102,317,484...102,339,403
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|
G |
BIRC5 |
baculoviral IAP repeat containing 5 |
decreases expression |
EXP |
morin results in decreased expression of BIRC5 mRNA |
CTD |
PMID:28689916 |
|
NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636
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|
G |
CASP10 |
caspase 10 |
increases expression |
EXP |
morin results in increased expression of CASP10 mRNA |
CTD |
PMID:28689916 |
|
NCBI chr 2:201,183,141...201,229,406
Ensembl chr 2:201,182,872...201,229,428
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|
G |
CASP3 |
caspase 3 |
multiple interactions increases activity |
ISO EXP |
morin inhibits the reaction [Acetaminophen results in increased activity of CASP3 protein]; morin inhibits the reaction [Acetaminophen results in increased cleavage of CASP3 protein]; morin inhibits the reaction [Diethylnitrosamine results in decreased expression of CASP3 protein]; morin inhibits the reaction [Ifosfamide results in increased activity of CASP3 protein]; morin inhibits the reaction [Streptozocin results in increased expression of CASP3 mRNA]; morin inhibits the reaction [titanium dioxide results in increased expression of CASP3 mRNA] morin results in increased activity of CASP3 protein |
CTD |
PMID:19931519 PMID:24726691 PMID:26767949 PMID:28844848 PMID:31722249 PMID:35414346 More...
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|
NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
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G |
CASP7 |
caspase 7 |
increases activity |
EXP |
morin results in increased activity of CASP7 protein |
CTD |
PMID:24726691 |
|
NCBI chr10:113,679,194...113,730,909
Ensembl chr10:113,679,162...113,730,907
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G |
CASP9 |
caspase 9 |
multiple interactions |
ISO |
morin inhibits the reaction [Acetaminophen results in increased activity of CASP9 protein]; morin inhibits the reaction [Diethylnitrosamine results in decreased expression of CASP9 protein] |
CTD |
PMID:19931519 PMID:26767949 |
|
NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
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G |
CAT |
catalase |
multiple interactions |
ISO |
Indomethacin promotes the reaction [morin inhibits the reaction [Freund's Adjuvant results in decreased activity of CAT protein]]; morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of CAT protein]; morin inhibits the reaction [[bisphenol S co-treated with diethyl phthalate] results in decreased activity of CAT protein]; morin inhibits the reaction [Acetaminophen results in decreased activity of CAT protein]; morin inhibits the reaction [Doxorubicin results in decreased activity of CAT protein]; morin inhibits the reaction [Excitatory Amino Acid Agonists results in decreased activity of CAT protein]; morin inhibits the reaction [Freund's Adjuvant results in decreased activity of CAT protein]; morin inhibits the reaction [Ifosfamide results in decreased activity of CAT protein]; morin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; morin promotes the reaction [Indomethacin inhibits the reaction [Freund's Adjuvant results in decreased activity of CAT protein]] |
CTD |
PMID:19201465 PMID:24854284 PMID:25698669 PMID:26767949 PMID:31100273 PMID:31722249 PMID:35414346 PMID:35900689 More...
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NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
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G |
CCL2 |
C-C motif chemokine ligand 2 |
multiple interactions |
ISO |
[morin co-treated with Indomethacin] inhibits the reaction [Freund's Adjuvant results in increased expression of CCL2 mRNA]; Indomethacin promotes the reaction [morin inhibits the reaction [Freund's Adjuvant results in increased expression of CCL2 protein]]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of CCL2 mRNA]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of CCL2 protein]; morin promotes the reaction [Indomethacin inhibits the reaction [Freund's Adjuvant results in increased expression of CCL2 protein]] |
CTD |
PMID:25698669 |
|
NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208
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G |
CCNB1 |
cyclin B1 |
decreases expression |
EXP |
morin results in decreased expression of CCNB1 mRNA |
CTD |
PMID:28689916 |
|
NCBI chr 5:69,167,150...69,178,245
Ensembl chr 5:69,167,135...69,178,245
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G |
CDC25C |
cell division cycle 25C |
decreases expression |
EXP |
morin results in decreased expression of CDC25C mRNA |
CTD |
PMID:28689916 |
|
NCBI chr 5:138,285,265...138,338,355
Ensembl chr 5:138,285,269...138,338,355
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G |
CDK1 |
cyclin dependent kinase 1 |
decreases expression |
EXP |
morin results in decreased expression of CDK1 mRNA |
CTD |
PMID:28689916 |
|
NCBI chr10:60,778,331...60,794,852
Ensembl chr10:60,778,331...60,794,852
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G |
CDKN1A |
cyclin dependent kinase inhibitor 1A |
increases expression |
EXP |
morin results in increased expression of CDKN1A mRNA |
CTD |
PMID:28689916 |
|
NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337
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G |
CHEK2 |
checkpoint kinase 2 |
decreases expression |
EXP |
morin results in decreased expression of CHEK2 mRNA |
CTD |
PMID:28689916 |
|
NCBI chr22:28,687,743...28,741,834
Ensembl chr22:28,687,743...28,742,422
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G |
COL2A1 |
collagen type II alpha 1 chain |
multiple interactions |
ISO |
2-chloro-5-nitrobenzanilide inhibits the reaction [morin inhibits the reaction [COL2A1 protein results in increased expression of FASN mRNA]]; morin inhibits the reaction [COL2A1 protein results in increased expression of FASN mRNA] |
CTD |
PMID:36121554 |
|
NCBI chr12:47,972,967...48,006,212
Ensembl chr12:47,972,967...48,004,554
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G |
CP |
ceruloplasmin |
multiple interactions |
ISO |
[Indomethacin co-treated with morin] inhibits the reaction [Freund's Adjuvant results in increased expression of CP protein]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of CP protein] |
CTD |
PMID:25698669 |
|
NCBI chr 3:149,162,414...149,221,829
Ensembl chr 3:149,162,410...149,221,829
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G |
CTSD |
cathepsin D |
multiple interactions |
ISO |
[morin co-treated with Indomethacin] inhibits the reaction [Freund's Adjuvant results in increased activity of CTSD protein]; morin inhibits the reaction [Freund's Adjuvant results in increased activity of CTSD protein] |
CTD |
PMID:25698669 |
|
NCBI chr11:1,752,755...1,763,927
Ensembl chr11:1,752,752...1,764,573
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G |
CYCS |
cytochrome c, somatic |
multiple interactions |
ISO |
morin inhibits the reaction [Diethylnitrosamine results in decreased expression of CYCS protein]; morin inhibits the reaction [Streptozocin results in increased expression of CYCS mRNA] |
CTD |
PMID:19931519 PMID:35414346 |
|
NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260
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|
G |
CYP1A1 |
cytochrome P450 family 1 subfamily A member 1 |
multiple interactions increases expression |
ISO EXP |
morin affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA] morin results in increased expression of CYP1A1 mRNA; morin results in increased expression of CYP1A1 protein AHR gene mutant form inhibits the reaction [morin results in increased expression of CYP1A1 mRNA] |
CTD |
PMID:20930378 PMID:29584932 |
|
NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
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G |
DIABLO |
diablo IAP-binding mitochondrial protein |
increases expression |
EXP |
morin results in increased expression of DIABLO mRNA |
CTD |
PMID:28689916 |
|
NCBI chr12:122,207,662...122,227,456
Ensembl chr12:122,207,668...122,226,062
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G |
DIO1 |
iodothyronine deiodinase 1 |
decreases activity |
EXP |
morin results in decreased activity of DIO1 protein |
CTD |
PMID:30561685 |
|
NCBI chr 1:53,894,187...53,911,086
Ensembl chr 1:53,891,239...53,911,086
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G |
DIO3 |
iodothyronine deiodinase 3 |
decreases activity |
EXP |
morin results in decreased activity of DIO3 protein |
CTD |
PMID:30561685 |
|
NCBI chr14:101,561,495...101,563,452
Ensembl chr14:101,560,139...101,563,452
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G |
EIF2A |
eukaryotic translation initiation factor 2A |
multiple interactions |
ISO |
[morin co-treated with 1,2-Dimethylhydrazine] results in increased phosphorylation of EIF2A protein |
CTD |
PMID:32028820 |
|
NCBI chr 3:150,546,787...150,586,016
Ensembl chr 3:150,546,678...150,586,016
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G |
EIF2AK3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
increases phosphorylation multiple interactions |
ISO |
morin results in increased phosphorylation of EIF2AK3 protein [1,2-Dimethylhydrazine co-treated with morin] results in increased expression of EIF2AK3 protein |
CTD |
PMID:32028820 |
|
NCBI chr 2:88,556,741...88,628,145
Ensembl chr 2:88,556,741...88,691,518
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G |
FADD |
Fas associated via death domain |
increases expression |
EXP |
morin results in increased expression of FADD mRNA |
CTD |
PMID:28689916 |
|
NCBI chr11:70,203,296...70,207,390
Ensembl chr11:70,203,296...70,207,390
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G |
FAS |
Fas cell surface death receptor |
multiple interactions |
ISO |
morin inhibits the reaction [titanium dioxide results in increased expression of FAS mRNA] |
CTD |
PMID:28844848 |
|
NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605
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G |
FASLG |
Fas ligand |
increases expression |
EXP |
morin results in increased expression of FASLG mRNA |
CTD |
PMID:28689916 |
|
NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876
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G |
FASN |
fatty acid synthase |
multiple interactions |
ISO |
2-chloro-5-nitrobenzanilide inhibits the reaction [morin inhibits the reaction [COL2A1 protein results in increased expression of FASN mRNA]]; morin inhibits the reaction [COL2A1 protein results in increased expression of FASN mRNA] |
CTD |
PMID:36121554 |
|
NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294
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G |
FOS |
Fos proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
ISO |
morin inhibits the reaction [Ifosfamide results in increased expression of FOS protein] |
CTD |
PMID:31722249 |
|
NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230
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G |
FSHB |
follicle stimulating hormone subunit beta |
multiple interactions |
ISO |
morin inhibits the reaction [titanium dioxide results in increased expression of FSHB protein] |
CTD |
PMID:28844848 |
|
NCBI chr11:30,231,014...30,235,194
Ensembl chr11:30,231,014...30,235,261
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G |
GFAP |
glial fibrillary acidic protein |
multiple interactions |
ISO |
morin inhibits the reaction [Ifosfamide results in increased expression of GFAP protein] |
CTD |
PMID:31722249 |
|
NCBI chr17:44,903,159...44,915,500
Ensembl chr17:44,903,159...44,916,937
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G |
GPT |
glutamic--pyruvic transaminase |
multiple interactions |
ISO |
morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased activity of GPT protein]; morin inhibits the reaction [Doxorubicin results in increased activity of GPT protein] |
CTD |
PMID:24854284 PMID:31100273 |
|
NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174
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G |
GPX1 |
glutathione peroxidase 1 |
multiple interactions |
ISO |
morin inhibits the reaction [[bisphenol S co-treated with diethyl phthalate] results in decreased activity of GPX1 protein] |
CTD |
PMID:35900689 |
|
NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605
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G |
GPX2 |
glutathione peroxidase 2 |
multiple interactions |
ISO |
[1,2-Dimethylhydrazine co-treated with morin] results in increased expression of GPX2 mRNA |
CTD |
PMID:32028820 |
|
NCBI chr14:64,939,158...64,942,745
Ensembl chr14:64,939,152...64,942,746
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G |
GSK3B |
glycogen synthase kinase 3 beta |
multiple interactions |
ISO |
morin inhibits the reaction [Acetaminophen results in decreased phosphorylation of GSK3B protein]; morin inhibits the reaction [Diethylnitrosamine results in increased expression of GSK3B protein modified form] |
CTD |
PMID:19931519 PMID:26767949 |
|
NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994
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G |
GSR |
glutathione-disulfide reductase |
multiple interactions |
ISO |
morin inhibits the reaction [Streptozocin results in decreased activity of GSR protein] |
CTD |
PMID:35414346 |
|
NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
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G |
HMOX1 |
heme oxygenase 1 |
multiple interactions |
ISO |
[1,2-Dimethylhydrazine co-treated with morin] results in increased expression of HMOX1 mRNA; morin inhibits the reaction [Acetaminophen results in decreased expression of HMOX1 protein] |
CTD |
PMID:26767949 PMID:32028820 |
|
NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
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|
G |
IFNG |
interferon gamma |
multiple interactions |
EXP |
morin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased abundance of Nitric Oxide] |
CTD |
PMID:22698256 |
|
NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
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|
G |
IL10 |
interleukin 10 |
multiple interactions |
ISO |
morin inhibits the reaction [[bisphenol S co-treated with diethyl phthalate] results in decreased expression of IL10 mRNA] |
CTD |
PMID:35900689 |
|
NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
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|
G |
IL17A |
interleukin 17A |
multiple interactions |
ISO |
[morin co-treated with Indomethacin] inhibits the reaction [Freund's Adjuvant results in increased expression of IL17A mRNA]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of IL17A mRNA] |
CTD |
PMID:25698669 |
|
NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638
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|
G |
IL1B |
interleukin 1 beta |
multiple interactions |
ISO |
morin inhibits the reaction [[Lipopolysaccharides co-treated with Thioglycolates] results in increased expression of IL1B mRNA]; morin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA] [morin co-treated with Indomethacin] inhibits the reaction [Freund's Adjuvant results in increased expression of IL1B mRNA]; Indomethacin promotes the reaction [morin inhibits the reaction [Freund's Adjuvant results in increased expression of IL1B protein]]; morin inhibits the reaction [[bisphenol S co-treated with diethyl phthalate] results in increased expression of IL1B mRNA]; morin inhibits the reaction [Doxorubicin results in increased expression of IL1B protein]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of IL1B mRNA]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of IL1B protein]; morin promotes the reaction [Indomethacin inhibits the reaction [Freund's Adjuvant results in increased expression of IL1B protein]] |
CTD |
PMID:22698256 PMID:25698669 PMID:31100273 PMID:35900689 |
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NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
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G |
IL6 |
interleukin 6 |
multiple interactions |
ISO |
morin inhibits the reaction [[Lipopolysaccharides co-treated with Thioglycolates] results in increased expression of IL6 mRNA]; morin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA] [morin co-treated with Indomethacin] inhibits the reaction [Freund's Adjuvant results in increased expression of IL6 mRNA]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of IL6 mRNA] |
CTD |
PMID:22698256 PMID:25698669 |
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NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
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G |
INS-IGF2 |
INS-IGF2 readthrough |
multiple interactions |
ISO |
morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of INS1 protein]; morin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein] |
CTD |
PMID:24854284 PMID:35414346 |
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NCBI chr11:2,129,117...2,161,209
Ensembl chr11:2,132,538...2,161,209
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G |
IYD |
iodotyrosine deiodinase |
multiple interactions |
EXP |
morin inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] |
CTD |
PMID:33352258 |
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NCBI chr 6:150,369,012...150,405,969
Ensembl chr 6:150,368,892...150,405,969
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G |
JUN |
Jun proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
ISO |
[morin co-treated with Indomethacin] inhibits the reaction [Freund's Adjuvant results in increased expression of JUN mRNA]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of JUN mRNA] |
CTD |
PMID:25698669 |
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NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048
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G |
KIT |
KIT proto-oncogene, receptor tyrosine kinase |
multiple interactions |
ISO |
morin inhibits the reaction [titanium dioxide results in decreased expression of KIT mRNA] |
CTD |
PMID:28844848 |
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NCBI chr 4:54,657,957...54,740,715
Ensembl chr 4:54,657,267...54,740,783
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G |
KRT1 |
keratin 1 |
multiple interactions |
ISO |
morin inhibits the reaction [Calcium results in increased expression of KRT1 mRNA] |
CTD |
PMID:12069687 |
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NCBI chr12:52,674,736...52,680,407
Ensembl chr12:52,674,736...52,680,407
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G |
LEP |
leptin |
multiple interactions |
ISO |
morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of LEP protein] |
CTD |
PMID:24854284 |
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NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629
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G |
LHB |
luteinizing hormone subunit beta |
multiple interactions |
ISO |
morin inhibits the reaction [titanium dioxide results in increased expression of LHB protein] |
CTD |
PMID:28844848 |
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NCBI chr19:49,015,980...49,019,498
Ensembl chr19:49,015,980...49,017,091
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G |
MAPK1 |
mitogen-activated protein kinase 1 |
multiple interactions |
ISO |
morin inhibits the reaction [Excitatory Amino Acid Agonists results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:19201465 |
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NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
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G |
MAPK3 |
mitogen-activated protein kinase 3 |
multiple interactions |
ISO |
morin inhibits the reaction [Excitatory Amino Acid Agonists results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:19201465 |
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NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
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G |
MAPK8 |
mitogen-activated protein kinase 8 |
multiple interactions |
ISO |
morin inhibits the reaction [Ifosfamide results in increased activity of MAPK8 protein] |
CTD |
PMID:31722249 |
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NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360
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G |
MGST1 |
microsomal glutathione S-transferase 1 |
multiple interactions |
ISO |
[1,2-Dimethylhydrazine co-treated with morin] results in increased expression of MGST1 mRNA |
CTD |
PMID:32028820 |
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NCBI chr12:16,347,115...16,593,331
Ensembl chr12:16,347,142...16,609,259
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G |
MMP2 |
matrix metallopeptidase 2 |
multiple interactions |
ISO |
morin inhibits the reaction [Diethylnitrosamine results in increased expression of MMP2 protein] |
CTD |
PMID:19539802 |
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NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691
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G |
MMP9 |
matrix metallopeptidase 9 |
multiple interactions decreases expression |
ISO |
morin inhibits the reaction [Diethylnitrosamine results in increased expression of MMP9 protein] morin results in decreased expression of MMP9 mRNA |
CTD |
PMID:16304905 PMID:19539802 |
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NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
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G |
MTOR |
mechanistic target of rapamycin kinase |
increases expression |
EXP |
morin results in increased expression of MTOR mRNA |
CTD |
PMID:28689916 |
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NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556
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G |
NFE2L2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions |
ISO |
[1,2-Dimethylhydrazine co-treated with morin] affects the localization of NFE2L2 protein; morin inhibits the reaction [Acetaminophen results in decreased expression of and affects the localization of NFE2L2 protein]; morin inhibits the reaction [Acetaminophen results in increased ubiquitination of and results in decreased expression of NFE2L2 protein]; morin inhibits the reaction [Ifosfamide results in decreased expression of NFE2L2 protein] |
CTD |
PMID:26767949 PMID:31722249 PMID:32028820 |
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NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
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G |
NOS1 |
nitric oxide synthase 1 |
multiple interactions |
ISO |
morin inhibits the reaction [Ifosfamide results in increased activity of NOS1 protein] |
CTD |
PMID:31722249 |
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NCBI chr12:117,208,142...117,361,626
Ensembl chr12:117,208,142...117,452,170
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G |
NOS2 |
nitric oxide synthase 2 |
multiple interactions |
ISO |
morin inhibits the reaction [[Lipopolysaccharides co-treated with Thioglycolates] results in increased expression of NOS2 mRNA] [morin co-treated with Indomethacin] inhibits the reaction [Freund's Adjuvant results in increased expression of NOS2 mRNA]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of NOS2 mRNA] |
CTD |
PMID:22698256 PMID:25698669 |
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NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
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G |
NPHS1 |
NPHS1 adhesion molecule, nephrin |
multiple interactions |
ISO |
morin inhibits the reaction [Doxorubicin affects the expression of NPHS1 protein] |
CTD |
PMID:31100273 |
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NCBI chr19:35,862,915...35,869,357
Ensembl chr19:35,825,964...35,869,287
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G |
NQO1 |
NAD(P)H quinone dehydrogenase 1 |
multiple interactions |
ISO |
morin inhibits the reaction [Acetaminophen results in decreased activity of NQO1 protein]; morin inhibits the reaction [Acetaminophen results in decreased expression of NQO1 protein] Morin enhances the reaction [Carbontetrachloride increases expression of Nqo1 mRNA in liver] |
CTD RGD |
PMID:26767949 PMID:29307993 |
RGD:25823195 |
NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
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G |
NTRK2 |
neurotrophic receptor tyrosine kinase 2 |
multiple interactions |
ISO |
morin inhibits the reaction [Streptozocin results in increased expression of NTRK2 mRNA] |
CTD |
PMID:35414346 |
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NCBI chr 9:84,668,522...85,027,054
Ensembl chr 9:84,668,375...85,095,751
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G |
PARP1 |
poly(ADP-ribose) polymerase 1 |
increases expression |
EXP |
morin results in increased expression of PARP1 mRNA |
CTD |
PMID:28689916 |
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NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154
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G |
PDE5A |
phosphodiesterase 5A |
multiple interactions |
ISO |
morin inhibits the reaction [[bisphenol S co-treated with diethyl phthalate] results in increased activity of PDE5A protein] |
CTD |
PMID:35900689 |
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NCBI chr 4:119,494,403...119,628,804
Ensembl chr 4:119,494,397...119,628,804
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G |
PDK1 |
pyruvate dehydrogenase kinase 1 |
multiple interactions |
ISO |
morin inhibits the reaction [Diethylnitrosamine results in increased expression of PDK1 protein modified form] |
CTD |
PMID:19931519 |
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NCBI chr 2:172,555,373...172,724,312
Ensembl chr 2:172,555,373...172,608,669
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G |
PHLPP2 |
PH domain and leucine rich repeat protein phosphatase 2 |
multiple interactions |
ISO |
morin inhibits the reaction [Acetaminophen results in increased expression of PHLPP2 protein] |
CTD |
PMID:26767949 |
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NCBI chr16:71,644,924...71,724,701
Ensembl chr16:71,637,835...71,724,701
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G |
PIK3CB |
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta |
increases expression |
EXP |
morin results in increased expression of PIK3CB mRNA |
CTD |
PMID:28689916 |
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NCBI chr 3:138,652,698...138,834,928
Ensembl chr 3:138,652,698...138,834,928
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G |
PPARG |
peroxisome proliferator activated receptor gamma |
multiple interactions affects binding affects localization |
ISO |
2-chloro-5-nitrobenzanilide inhibits the reaction [morin promotes the reaction [PPARG protein binds to SP1 protein]]; morin promotes the reaction [PPARG protein binds to SP1 protein] morin binds to PPARG protein morin affects the localization of PPARG protein |
CTD |
PMID:36121554 |
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NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
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G |
PRKAB1 |
protein kinase AMP-activated non-catalytic subunit beta 1 |
decreases expression |
EXP |
morin results in decreased expression of PRKAB1 mRNA |
CTD |
PMID:28689916 |
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NCBI chr12:119,667,952...119,681,619
Ensembl chr12:119,667,864...119,681,624
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G |
PRKCE |
protein kinase C epsilon |
decreases expression |
EXP |
morin results in decreased expression of PRKCE mRNA |
CTD |
PMID:28689916 |
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NCBI chr 2:45,651,279...46,187,990
Ensembl chr 2:45,651,345...46,187,990
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G |
PTEN |
phosphatase and tensin homolog |
multiple interactions |
ISO |
morin inhibits the reaction [Diethylnitrosamine results in decreased expression of PTEN protein modified form] |
CTD |
PMID:19931519 |
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NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930
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G |
PTGS2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
ISO |
[morin co-treated with Indomethacin] inhibits the reaction [Freund's Adjuvant results in increased expression of PTGS2 mRNA]; Indomethacin promotes the reaction [morin inhibits the reaction [Freund's Adjuvant results in increased expression of PTGS2 protein]]; morin inhibits the reaction [Diethylnitrosamine results in increased expression of PTGS2 mRNA]; morin inhibits the reaction [Diethylnitrosamine results in increased expression of PTGS2 protein]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of PTGS2 mRNA]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of PTGS2 protein]; morin promotes the reaction [Indomethacin inhibits the reaction [Freund's Adjuvant results in increased expression of PTGS2 protein]] |
CTD |
PMID:19539802 PMID:25698669 |
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NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
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G |
PTPN1 |
protein tyrosine phosphatase non-receptor type 1 |
decreases activity |
EXP |
morin results in decreased activity of PTPN1 protein |
CTD |
PMID:29175190 |
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NCBI chr20:50,510,383...50,585,241
Ensembl chr20:50,510,321...50,585,241
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G |
RELA |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
ISO |
[morin co-treated with Indomethacin] inhibits the reaction [Freund's Adjuvant results in increased expression of RELA mRNA]; Indomethacin promotes the reaction [morin inhibits the reaction [Freund's Adjuvant results in increased expression of RELA protein]]; morin inhibits the reaction [[bisphenol S co-treated with diethyl phthalate] results in increased expression of RELA protein]; morin inhibits the reaction [Diethylnitrosamine results in increased expression of RELA mRNA]; morin inhibits the reaction [Diethylnitrosamine results in increased expression of RELA protein]; morin inhibits the reaction [Diethylnitrosamine results in increased localization of RELA protein]; morin inhibits the reaction [Excitatory Amino Acid Agonists affects the localization of and results in increased activity of RELA protein]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of RELA mRNA]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of RELA protein]; morin promotes the reaction [Indomethacin inhibits the reaction [Freund's Adjuvant results in increased expression of RELA protein]] |
CTD |
PMID:19201465 PMID:19539802 PMID:25698669 PMID:35900689 |
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NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090
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G |
RPS6KB1 |
ribosomal protein S6 kinase B1 |
increases expression |
EXP |
morin results in increased expression of RPS6KB1 mRNA |
CTD |
PMID:28689916 |
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NCBI chr17:59,893,121...59,950,574
Ensembl chr17:59,893,046...59,950,574
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G |
SLC16A1 |
solute carrier family 16 member 1 |
multiple interactions |
EXP ISO |
morin inhibits the reaction [SLC16A1 protein results in increased uptake of Benzoic Acid] [morin results in decreased activity of SLC16A1 protein] which results in decreased uptake of Sodium Oxybate |
CTD |
PMID:17108059 PMID:17976262 |
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NCBI chr 1:112,911,847...112,956,196
Ensembl chr 1:112,911,847...112,957,593
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G |
SOD1 |
superoxide dismutase 1 |
multiple interactions |
ISO |
morin inhibits the reaction [[bisphenol S co-treated with diethyl phthalate] results in decreased activity of SOD1 protein] |
CTD |
PMID:35900689 |
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NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931
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G |
SP1 |
Sp1 transcription factor |
multiple interactions |
ISO |
2-chloro-5-nitrobenzanilide inhibits the reaction [morin promotes the reaction [PPARG protein binds to SP1 protein]]; morin promotes the reaction [PPARG protein binds to SP1 protein] |
CTD |
PMID:36121554 |
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NCBI chr12:53,380,176...53,416,446
Ensembl chr12:53,380,176...53,416,446
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G |
STAR |
steroidogenic acute regulatory protein |
multiple interactions |
ISO |
morin inhibits the reaction [titanium dioxide results in decreased expression of STAR mRNA] |
CTD |
PMID:28844848 |
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NCBI chr 8:38,142,700...38,150,952
Ensembl chr 8:38,142,700...38,150,992
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G |
TGFB1 |
transforming growth factor beta 1 |
multiple interactions |
ISO |
morin inhibits the reaction [Dimethylnitrosamine results in increased expression of TGFB1 mRNA]; morin inhibits the reaction [Dimethylnitrosamine results in increased expression of TGFB1 protein] |
CTD |
PMID:18629640 |
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NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
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G |
TNF |
tumor necrosis factor |
multiple interactions |
ISO |
morin inhibits the reaction [[Lipopolysaccharides co-treated with Thioglycolates] results in increased expression of TNF mRNA]; morin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; morin inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] [Indomethacin co-treated with morin] inhibits the reaction [Freund's Adjuvant results in increased expression of TNF mRNA]; Indomethacin promotes the reaction [morin inhibits the reaction [Freund's Adjuvant results in increased expression of TNF protein]]; morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein]; morin inhibits the reaction [[bisphenol S co-treated with diethyl phthalate] results in increased expression of TNF mRNA]; morin inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of TNF mRNA]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of TNF protein]; morin inhibits the reaction [Ifosfamide results in increased expression of TNF protein]; morin inhibits the reaction [titanium dioxide results in increased expression of TNF protein]; morin promotes the reaction [Indomethacin inhibits the reaction [Freund's Adjuvant results in increased expression of TNF protein]] |
CTD |
PMID:22698256 PMID:24854284 PMID:25698669 PMID:28844848 PMID:31100273 PMID:31722249 PMID:35900689 More...
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NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
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G |
TNFRSF10B |
TNF receptor superfamily member 10b |
increases expression |
EXP |
morin results in increased expression of TNFRSF10B mRNA |
CTD |
PMID:28689916 |
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NCBI chr 8:23,020,133...23,069,031
Ensembl chr 8:23,020,133...23,069,031
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G |
TNFRSF25 |
TNF receptor superfamily member 25 |
increases expression |
EXP |
morin results in increased expression of TNFRSF25 mRNA |
CTD |
PMID:28689916 |
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NCBI chr 1:6,460,786...6,466,173
Ensembl chr 1:6,460,786...6,466,175
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G |
TNFSF11 |
TNF superfamily member 11 |
multiple interactions |
ISO |
[morin co-treated with Indomethacin] inhibits the reaction [Freund's Adjuvant results in increased expression of TNFSF11 mRNA]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of TNFSF11 mRNA] |
CTD |
PMID:25698669 |
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NCBI chr13:42,562,736...42,608,013
Ensembl chr13:42,562,736...42,608,013
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G |
TP53 |
tumor protein p53 |
increases expression multiple interactions |
EXP ISO |
morin results in increased expression of TP53 mRNA morin inhibits the reaction [Ifosfamide results in increased expression of TP53 protein] |
CTD |
PMID:28689916 PMID:31722249 |
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NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
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G |
TXNRD1 |
thioredoxin reductase 1 |
multiple interactions |
ISO |
[1,2-Dimethylhydrazine co-treated with morin] results in increased expression of TXNRD1 mRNA |
CTD |
PMID:32028820 |
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NCBI chr12:104,215,779...104,350,307
Ensembl chr12:104,215,779...104,350,307
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G |
UGT1A1 |
UDP glucuronosyltransferase family 1 member A1 |
increases glucuronidation decreases activity multiple interactions |
EXP |
UGT1A1 protein results in increased glucuronidation of morin morin results in decreased activity of UGT1A1 protein AHR gene mutant form inhibits the reaction [morin results in increased expression of UGT1A1 mRNA] |
CTD |
PMID:14557274 PMID:29584932 PMID:35063619 |
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NCBI chr 2:233,760,270...233,773,300
Ensembl chr 2:233,760,270...233,773,300
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G |
UGT1A10 |
UDP glucuronosyltransferase family 1 member A10 |
increases glucuronidation decreases activity |
EXP |
UGT1A10 protein results in increased glucuronidation of morin morin results in decreased activity of UGT1A10 protein |
CTD |
PMID:14557274 PMID:35063619 |
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NCBI chr 2:233,636,448...233,773,300
Ensembl chr 2:233,636,448...233,773,300
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G |
UGT1A3 |
UDP glucuronosyltransferase family 1 member A3 |
decreases activity |
EXP |
morin results in decreased activity of UGT1A3 protein |
CTD |
PMID:35063619 |
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NCBI chr 2:233,729,042...233,773,300
Ensembl chr 2:233,729,042...233,773,300
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G |
UGT1A5 |
UDP glucuronosyltransferase family 1 member A5 |
multiple interactions |
ISO |
[1,2-Dimethylhydrazine co-treated with morin] results in increased expression of UGT1A5 mRNA |
CTD |
PMID:32028820 |
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NCBI chr 2:233,712,907...233,773,300
Ensembl chr 2:233,712,907...233,773,300
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G |
UGT1A6 |
UDP glucuronosyltransferase family 1 member A6 |
decreases activity |
EXP |
morin results in decreased activity of UGT1A6 protein |
CTD |
PMID:35063619 |
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NCBI chr 2:233,691,702...233,773,300
Ensembl chr 2:233,691,607...233,773,300
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G |
UGT1A7 |
UDP glucuronosyltransferase family 1 member A7 |
increases glucuronidation decreases activity |
EXP |
UGT1A7 protein results in increased glucuronidation of morin morin results in decreased activity of UGT1A7 protein |
CTD |
PMID:14557274 PMID:35063619 |
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NCBI chr 2:233,681,901...233,773,300
Ensembl chr 2:233,681,901...233,773,300
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G |
UGT1A8 |
UDP glucuronosyltransferase family 1 member A8 |
increases glucuronidation |
EXP |
UGT1A8 protein results in increased glucuronidation of morin |
CTD |
PMID:14557274 |
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NCBI chr 2:233,617,633...233,773,300
Ensembl chr 2:233,617,633...233,773,300
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G |
UGT1A9 |
UDP glucuronosyltransferase family 1 member A9 |
increases glucuronidation decreases activity |
EXP |
UGT1A9 protein results in increased glucuronidation of morin morin results in decreased activity of UGT1A9 protein |
CTD |
PMID:14557274 PMID:35063619 |
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NCBI chr 2:233,671,898...233,773,300
Ensembl chr 2:233,671,898...233,773,300
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G |
UGT2B15 |
UDP glucuronosyltransferase family 2 member B15 |
decreases activity |
EXP |
morin results in decreased activity of UGT2B15 protein |
CTD |
PMID:35063619 |
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NCBI chr 4:68,646,597...68,670,652
Ensembl chr 4:68,646,597...68,670,652
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G |
UGT2B7 |
UDP glucuronosyltransferase family 2 member B7 |
decreases activity |
EXP |
morin results in decreased activity of UGT2B7 protein |
CTD |
PMID:35063619 |
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NCBI chr 4:69,051,375...69,112,987
Ensembl chr 4:69,051,363...69,112,987
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G |
VEGFA |
vascular endothelial growth factor A |
multiple interactions |
ISO |
Indomethacin promotes the reaction [morin inhibits the reaction [Freund's Adjuvant results in increased expression of VEGFA protein]]; morin inhibits the reaction [[bisphenol S co-treated with diethyl phthalate] results in increased expression of VEGFA mRNA]; morin inhibits the reaction [Freund's Adjuvant results in increased expression of VEGFA protein]; morin promotes the reaction [Indomethacin inhibits the reaction [Freund's Adjuvant results in increased expression of VEGFA protein]] |
CTD |
PMID:25698669 PMID:35900689 |
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NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487
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G |
WEE1 |
WEE1 G2 checkpoint kinase |
increases expression |
EXP |
morin results in increased expression of WEE1 mRNA |
CTD |
PMID:28689916 |
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NCBI chr11:9,573,670...9,589,985
Ensembl chr11:9,573,670...9,593,457
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