TNFRSF25 (TNF receptor superfamily member 25) - Rat Genome Database
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Gene: TNFRSF25 (TNF receptor superfamily member 25) Homo sapiens
Analyze
Symbol: TNFRSF25
Name: TNF receptor superfamily member 25
RGD ID: 1312746
HGNC Page HGNC
Description: Predicted to have tumor necrosis factor-activated receptor activity. Predicted to be involved in apoptotic signaling pathway and tumor necrosis factor-mediated signaling pathway. Localizes to plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: APO-3; apoptosis inducing receptor; apoptosis-inducing receptor AIR; apoptosis-mediating receptor DR3; apoptosis-mediating receptor TRAMP; DDR3; death domain receptor 3 soluble form; death receptor 3; death receptor beta; DR3; GEF720; Guanine nucleotide exchange factor 720; LARD; lymphocyte associated receptor of death; lymphocyte-associated receptor of death; PH domain-containing family G member 5; Pleckstrin homology domain-containing family G member 5; PLEKHG5; TNFRSF12; TR3; TRAMP; translocating chain-association membrane protein; tumor necrosis factor receptor superfamily member 25; tumor necrosis factor receptor superfamily, member 12 (translocating chain-association membrane protein); tumor necrosis factor receptor superfamily, member 25; WSL-1; WSL-LR
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl16,460,786 - 6,466,195 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl16,460,786 - 6,466,175 (-)EnsemblGRCh38hg38GRCh38
GRCh3816,460,786 - 6,466,173 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3716,520,787 - 6,527,432 (-)NCBIGRCh37GRCh37hg19GRCh37
GRCh3716,520,846 - 6,526,233 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3616,443,798 - 6,448,842 (-)NCBINCBI36hg18NCBI36
Build 3416,455,481 - 6,460,521NCBI
Celera15,635,659 - 5,640,703 (-)NCBI
Cytogenetic Map1p36.31NCBI
HuRef15,668,754 - 5,673,798 (-)NCBIHuRef
CHM1_116,509,749 - 6,514,768 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,3'-diindolylmethane  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
acetamide  (ISO)
acetylsalicylic acid  (EXP)
aldehydo-D-glucose  (ISO)
amphetamine  (ISO)
arsane  (EXP)
arsenic atom  (EXP)
arsenous acid  (EXP,ISO)
benzo[a]pyrene  (EXP)
bisphenol A  (EXP,ISO)
Brevetoxin B  (EXP)
cadmium atom  (EXP)
capsaicin  (EXP)
carbon nanotube  (ISO)
chloroprene  (ISO)
choline  (ISO)
chromium(6+)  (EXP)
cisplatin  (EXP)
cocaine  (ISO)
copper(II) sulfate  (EXP)
cyclosporin A  (EXP)
D-glucose  (ISO)
diarsenic trioxide  (EXP,ISO)
diazinon  (EXP)
diethylstilbestrol  (EXP,ISO)
dioscin  (EXP)
disodium selenite  (EXP)
dorsomorphin  (EXP)
doxorubicin  (EXP)
folic acid  (ISO)
fonofos  (EXP)
furan  (ISO)
furosemide  (ISO)
genistein  (EXP)
glucose  (ISO)
hesperidin  (EXP)
hydrogen peroxide  (EXP)
hydroquinone  (EXP)
L-methionine  (ISO)
lipopolysaccharide  (EXP)
manganese atom  (EXP)
manganese(0)  (EXP)
manganese(II) chloride  (EXP)
melittin  (EXP)
metformin  (EXP)
methotrexate  (EXP)
methylseleninic acid  (EXP)
microcystin RR  (EXP)
morin  (EXP)
N-methyl-N'-nitro-N-nitrosoguanidine  (EXP)
nickel sulfate  (EXP)
p-menthan-3-ol  (EXP)
paclitaxel  (EXP)
paraquat  (EXP)
parathion  (EXP)
phenylarsine oxide  (EXP)
potassium chromate  (EXP)
propylparaben  (EXP)
raloxifene  (EXP)
SB 431542  (EXP)
sodium fluoride  (ISO)
sunitinib  (EXP)
terbufos  (EXP)
tetrachloromethane  (ISO)
thymoquinone  (EXP)
titanium dioxide  (ISO)
trichloroethene  (ISO)
trimellitic anhydride  (ISO)
trimethyltin  (ISO)
urethane  (EXP)
valproic acid  (EXP)
venom  (EXP)
vorinostat  (EXP)
zearalenone  (EXP)
zoledronic acid  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:8875942   PMID:8889548   PMID:8934525   PMID:8994832   PMID:9052839   PMID:9114039   PMID:9446802   PMID:9560245   PMID:9615223   PMID:9915703   PMID:11094155   PMID:11181995  
PMID:11376335   PMID:11606045   PMID:11793848   PMID:11819535   PMID:11911831   PMID:12477932   PMID:12875962   PMID:12882979   PMID:12975309   PMID:14702039   PMID:14759258   PMID:15241467  
PMID:15301860   PMID:15760679   PMID:16517446   PMID:16986165   PMID:17085968   PMID:18411341   PMID:19674013   PMID:19773279   PMID:20125169   PMID:20568250   PMID:21153333   PMID:21421854  
PMID:21672030   PMID:21722370   PMID:21873635   PMID:22043900   PMID:22641456   PMID:22956587   PMID:23443464   PMID:23658110   PMID:24832108   PMID:25044706   PMID:25083589   PMID:25269704  
PMID:25370568   PMID:25399326   PMID:25509355   PMID:25929035   PMID:26046454   PMID:26065008   PMID:26072972   PMID:26393680   PMID:26509650   PMID:26760575   PMID:26810853   PMID:27001939  
PMID:27592300   PMID:27665176   PMID:27682848   PMID:28062298   PMID:28183800   PMID:28337757   PMID:28941993   PMID:31135876   PMID:31299941   PMID:31358760   PMID:31628153  


Genomics

Comparative Map Data
TNFRSF25
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl16,460,786 - 6,466,195 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl16,460,786 - 6,466,175 (-)EnsemblGRCh38hg38GRCh38
GRCh3816,460,786 - 6,466,173 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3716,520,787 - 6,527,432 (-)NCBIGRCh37GRCh37hg19GRCh37
GRCh3716,520,846 - 6,526,233 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3616,443,798 - 6,448,842 (-)NCBINCBI36hg18NCBI36
Build 3416,455,481 - 6,460,521NCBI
Celera15,635,659 - 5,640,703 (-)NCBI
Cytogenetic Map1p36.31NCBI
HuRef15,668,754 - 5,673,798 (-)NCBIHuRef
CHM1_116,509,749 - 6,514,768 (-)NCBICHM1_1
Tnfrsf25
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394152,199,985 - 152,204,576 (+)NCBIGRCm39mm39
GRCm384152,115,528 - 152,120,119 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4152,115,934 - 152,120,119 (+)EnsemblGRCm38mm10GRCm38
MGSCv374151,490,452 - 151,494,220 (+)NCBIGRCm37mm9NCBIm37
MGSCv364150,959,734 - 150,963,919 (+)NCBImm8
Celera4154,402,873 - 154,406,641 (+)NCBICelera
Cytogenetic Map4E2NCBI
Tnfrsf25
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25162,621,669 - 162,626,341 (+)NCBI
Rnor_6.0 Ensembl5169,288,871 - 169,293,137 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.05169,288,419 - 169,293,137 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05172,846,849 - 172,851,588 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45169,344,695 - 169,348,961 (+)NCBIRGSC3.4rn4RGSC3.4
Celera5160,854,219 - 160,858,485 (+)NCBICelera
Cytogenetic Map5q36NCBI
Tnfrsf25
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554866,122,454 - 6,126,782 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554866,121,906 - 6,127,060 (+)NCBIChiLan1.0ChiLan1.0
TNFRSF25
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.116,475,460 - 6,480,424 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl16,475,498 - 6,480,424 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v015,222,680 - 5,228,211 (-)NCBIMhudiblu_PPA_v0panPan3
TNFRSF25
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl560,316,688 - 60,320,897 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1560,316,473 - 60,321,299 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Tnfrsf25
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049366231,249,979 - 1,254,273 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TNFRSF25
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl667,316,825 - 67,321,442 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1667,316,818 - 67,321,442 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2662,269,346 - 62,274,497 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TNFRSF25
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120125,276,632 - 125,282,090 (+)NCBI
ChlSab1.1 Ensembl20125,277,680 - 125,281,995 (+)Ensembl
Tnfrsf25
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248185,010,508 - 5,012,453 (+)NCBI

Position Markers
SHGC-74161  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3716,520,877 - 6,520,976UniSTSGRCh37
Build 3616,443,464 - 6,443,563RGDNCBI36
Celera15,635,325 - 5,635,424RGD
Cytogenetic Map1p36.31UniSTS
Cytogenetic Map1p36.2UniSTS
HuRef15,668,420 - 5,668,519UniSTS
TNG Radiation Hybrid Map12255.0UniSTS
GeneMap99-GB4 RH Map130.33UniSTS
SHGC-74157  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3716,526,358 - 6,526,515UniSTSGRCh37
Build 3616,448,945 - 6,449,102RGDNCBI36
Celera15,640,806 - 5,640,963RGD
Cytogenetic Map1p36.31UniSTS
Cytogenetic Map1p36.2UniSTS
HuRef15,673,901 - 5,674,058UniSTS
TNG Radiation Hybrid Map12221.0UniSTS
GeneMap99-GB4 RH Map127.0UniSTS
SHGC-57889  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3716,521,289 - 6,521,637UniSTSGRCh37
Build 3616,443,876 - 6,444,224RGDNCBI36
Celera15,635,737 - 5,636,085RGD
Cytogenetic Map1p36.2UniSTS
HuRef15,668,832 - 5,669,180UniSTS
TNG Radiation Hybrid Map12255.0UniSTS
D11S3114  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map9q34.13UniSTS
Cytogenetic Map15q13UniSTS
Cytogenetic Map3p22-p21.3UniSTS
Cytogenetic Map1q32.1UniSTS
Cytogenetic Map7p14.1UniSTS
Cytogenetic Map2q22.3UniSTS
Cytogenetic Map3p24.3UniSTS
Cytogenetic Map17q25.3UniSTS
Cytogenetic Map7q31.1UniSTS
Cytogenetic Map7q21.11UniSTS
Cytogenetic Map5q31UniSTS
Cytogenetic Map22q13.33UniSTS
Cytogenetic Map8q22.3UniSTS
Cytogenetic Map2p25.1UniSTS
Cytogenetic Map3q22-q24UniSTS
Cytogenetic Map5q23.3-q31.1UniSTS
Cytogenetic Map8p21.3UniSTS
Cytogenetic Map14q32.3UniSTS
Cytogenetic Map7q11.23UniSTS
Cytogenetic Map7q32UniSTS
Cytogenetic Map17q11UniSTS
Cytogenetic Map1q21-q23UniSTS
Cytogenetic Map12q13.13UniSTS
Cytogenetic Map17p12-p11.2UniSTS
Cytogenetic Map6p21.1UniSTS
Cytogenetic MapXp22.2UniSTS
Cytogenetic Map19p13.11UniSTS
Cytogenetic Map19p13.2UniSTS
Cytogenetic Map16q24.3UniSTS
Cytogenetic Map9q34.3UniSTS
Cytogenetic Map19q13.33UniSTS
Cytogenetic Map2q32.3UniSTS
Cytogenetic Map1q25.1UniSTS
Cytogenetic Map10p15.3UniSTS
Cytogenetic Map12q12UniSTS
Cytogenetic Map12q24.31UniSTS
Cytogenetic Map15q15UniSTS
Cytogenetic Map22q11.23UniSTS
Cytogenetic Map17q25UniSTS
Cytogenetic Map16q22.1UniSTS
Cytogenetic Map19p13.3UniSTS
Cytogenetic Map5q23.3UniSTS
Cytogenetic Map15q15.1UniSTS
Cytogenetic Map3q27.2UniSTS
Cytogenetic Map20q13.12UniSTS
Cytogenetic MapXp11.23UniSTS
Cytogenetic Map16q13UniSTS
Cytogenetic Map19q13.3UniSTS
Cytogenetic Map1q32UniSTS
Cytogenetic Map6q25.3UniSTS
Cytogenetic Map1p36.2UniSTS
Cytogenetic Map15q11.2-q21.3UniSTS
Cytogenetic Map14q24.3UniSTS
Cytogenetic Map19p13UniSTS
Cytogenetic Map1p35.1UniSTS
Cytogenetic Map17q11.2UniSTS
Cytogenetic Map12q13.2UniSTS
Cytogenetic Map22q13.1UniSTS
Cytogenetic Map11p15UniSTS
Cytogenetic Map8q24.13UniSTS
Cytogenetic Map1q41UniSTS
Cytogenetic Map19q13.12UniSTS
Cytogenetic Map17q12UniSTS
Cytogenetic Map12p12.1UniSTS
Cytogenetic Map15q25.2UniSTS
Cytogenetic Map2p13.1UniSTS
Cytogenetic Map1p36.13UniSTS
Cytogenetic Map2q12.1UniSTS
Cytogenetic Map11q23.3UniSTS
Cytogenetic MapXp11.3UniSTS
Cytogenetic Map17p13UniSTS
Cytogenetic Map20q13.13UniSTS
Cytogenetic Map4q12UniSTS
Cytogenetic Map16q24UniSTS
Cytogenetic Map17p13.1UniSTS
Cytogenetic Map10q23.1UniSTS
Cytogenetic Map1q44UniSTS
Cytogenetic Map3p21.31UniSTS
Cytogenetic Map17p13.2UniSTS
Cytogenetic Map9q33.3UniSTS
Cytogenetic Map2p11.2UniSTS
Cytogenetic Map22q12.1UniSTS
Cytogenetic Map17q22.2UniSTS
Cytogenetic Map1p36.33UniSTS
Cytogenetic Map10q11.1UniSTS
Cytogenetic Map19q12UniSTS
Cytogenetic Map11q14.2UniSTS
Cytogenetic Map1q23.1UniSTS
Cytogenetic Map11p15.4UniSTS
Cytogenetic Map18q12.1-q21.1UniSTS
Cytogenetic Map2q37UniSTS
Cytogenetic Map20q11.21UniSTS
Cytogenetic Map6p21.32UniSTS
Cytogenetic Map10q26.3UniSTS
Cytogenetic Map7q22.1UniSTS
Cytogenetic Map14q12UniSTS
Cytogenetic Map8p11.22UniSTS
Cytogenetic Map19q13.32UniSTS
Cytogenetic Map17q21.31UniSTS
Cytogenetic Map17q21UniSTS
Cytogenetic Map2q21.3UniSTS
Cytogenetic Map2q21.1UniSTS
Cytogenetic Map6q27UniSTS
Cytogenetic Map2q33.1UniSTS
Cytogenetic Map9q21.12UniSTS
Cytogenetic Map7p22.2UniSTS
Cytogenetic Map20p13UniSTS
Cytogenetic Map17q25.1UniSTS
Cytogenetic Map10q24.31UniSTS
Cytogenetic Map15q22.31UniSTS
Cytogenetic Map11q12.3UniSTS
Cytogenetic Map2q31.1UniSTS
Cytogenetic Map1p36.21UniSTS
Cytogenetic Map1p31.1UniSTS
Cytogenetic Map1p36.11UniSTS
Cytogenetic Map1p32.3UniSTS
Cytogenetic Map3q13.31UniSTS
Cytogenetic Map6q13UniSTS
Cytogenetic Map1q21UniSTS
Cytogenetic Map3q21.3UniSTS
Cytogenetic Map19q13.4UniSTS
Cytogenetic Map12q23.2UniSTS
Cytogenetic Map1q21.3UniSTS
Cytogenetic Map1q22UniSTS
Cytogenetic Map1p36UniSTS
Cytogenetic Map4p14UniSTS
Cytogenetic Map19p12UniSTS
Cytogenetic Map22q11.21UniSTS
Cytogenetic Map7q22UniSTS
Cytogenetic Map16q22UniSTS
Cytogenetic Map2q11.2UniSTS
Cytogenetic Map19p13.1-p12UniSTS
Cytogenetic Map16p13.3UniSTS
Cytogenetic Map2p22.1UniSTS
Cytogenetic Map1p34.3UniSTS
Cytogenetic Map5q23.1UniSTS
Cytogenetic Map8q24.3UniSTS
Cytogenetic Map1q25UniSTS
Cytogenetic Map1q21.2UniSTS
Cytogenetic Map12q22UniSTS
Cytogenetic Map21q22.3UniSTS
Cytogenetic Map21q22.11UniSTS
Cytogenetic Map3q23UniSTS
Cytogenetic Map6p21.3UniSTS
Cytogenetic Map2q12.3UniSTS
Cytogenetic Map12p13.31UniSTS
Cytogenetic Map8p11.2UniSTS
Cytogenetic Map7q21.1UniSTS
Cytogenetic Map19q13.43UniSTS
Cytogenetic Map2q35UniSTS
Cytogenetic Map5q35.3UniSTS
Cytogenetic Map5p13UniSTS
Cytogenetic Map22q11.2UniSTS
Cytogenetic Map5p12UniSTS
Cytogenetic Map1p34.2UniSTS
Cytogenetic Map12q21.1UniSTS
Cytogenetic Map16q12.1UniSTS
Cytogenetic Map2q37.1UniSTS
Cytogenetic Map7p14.3UniSTS
Cytogenetic MapXq13.2UniSTS
Cytogenetic Map18p11.21UniSTS
Cytogenetic Map17p13.3UniSTS
Cytogenetic Map14q24UniSTS
Cytogenetic Map15q24.1UniSTS
Cytogenetic Map7p22.3UniSTS
Cytogenetic Map22q13.2UniSTS
Cytogenetic Map2p21UniSTS
Cytogenetic Map22q11.1UniSTS
Cytogenetic Map22q13UniSTS
Cytogenetic Map11q13.1-q13.2UniSTS
Cytogenetic Map7p22UniSTS
Cytogenetic Map1p32-p31UniSTS
Cytogenetic Map19q13.1UniSTS
Cytogenetic Map11q13UniSTS
Cytogenetic Map7q21-q22UniSTS
Cytogenetic Map11p15.5UniSTS
Cytogenetic Map12p13.1UniSTS
Cytogenetic Map8p22UniSTS
Cytogenetic Map3q25.33UniSTS
Cytogenetic Map10q23.31UniSTS
Cytogenetic Map1p13.3UniSTS
Cytogenetic Map20q13.3UniSTS
Cytogenetic Map17q23.2UniSTS
Cytogenetic Map14q24.1UniSTS
Cytogenetic Map1p36.32UniSTS
Cytogenetic Map10q24.32UniSTS
Cytogenetic Map2q33.2UniSTS
Cytogenetic Map1p35-p34.3UniSTS
Cytogenetic Map7p11.2UniSTS
Cytogenetic Map5q35.2UniSTS
Cytogenetic Map10q22.3UniSTS
Cytogenetic Map2p13.3UniSTS
Cytogenetic Map3q12.3UniSTS
Cytogenetic Map12qUniSTS
Cytogenetic Map12p12.2-p11.2UniSTS
Cytogenetic Map2p23.3UniSTS
Cytogenetic Map2q14.3UniSTS
Cytogenetic Map7p13UniSTS
Cytogenetic Map11p15.3UniSTS
Cytogenetic Map1p36.11-p34.2UniSTS
Cytogenetic Map4q35.1UniSTS
Cytogenetic Map6q22.31UniSTS
Cytogenetic Map11q13.1UniSTS
Cytogenetic Map16q22.2UniSTS
Cytogenetic Map11q22.3UniSTS
Cytogenetic Map10p14UniSTS
Cytogenetic Map8q22.1UniSTS
Cytogenetic Map6q21UniSTS
Cytogenetic Map4p16.1UniSTS
Cytogenetic Map20p11.23UniSTS
Cytogenetic Map3q22.3UniSTS
Cytogenetic Map3q27.3UniSTS
Cytogenetic Map22q12.2UniSTS
Cytogenetic Map14q32.11UniSTS
Cytogenetic Map15q14UniSTS
Cytogenetic Map5q31.3UniSTS
Cytogenetic Map11q14UniSTS
Cytogenetic Map15q21UniSTS
Cytogenetic Map3q27.1UniSTS
Cytogenetic Map3p14.3UniSTS
Cytogenetic Map12p13.2UniSTS
Cytogenetic Map6p21.2UniSTS
Cytogenetic Map10q11.1-q24UniSTS
Cytogenetic Map1p36.31UniSTS
Cytogenetic Map1p31.3UniSTS
Cytogenetic MapXp11.22UniSTS
Cytogenetic Map10p15.1UniSTS
Cytogenetic MapXq24UniSTS
Cytogenetic Map7p22.1UniSTS
Cytogenetic Map14q31.1UniSTS
Cytogenetic Map19q13.2UniSTS
Cytogenetic MapXq21.1UniSTS
Cytogenetic Map15q22UniSTS
Cytogenetic Map6p25UniSTS
Cytogenetic Map16p11.2UniSTS
Cytogenetic MapXq12-q13UniSTS
Cytogenetic Map12q13.3UniSTS
Cytogenetic Map9q34.11UniSTS
Cytogenetic Map7q31UniSTS
Cytogenetic Map7q31.1-q31.3UniSTS
Cytogenetic Map11q13.4UniSTS
Cytogenetic Map7q34UniSTS
Cytogenetic MapXq13.1-q21.1UniSTS
Cytogenetic Map20pter-q12UniSTS
Cytogenetic Map14q32.31UniSTS
Cytogenetic Map12q13.11-q14.3UniSTS
Cytogenetic Map2q32.1UniSTS
Cytogenetic Map15q21-q22UniSTS
Cytogenetic Map19q13UniSTS
Cytogenetic Map20q11.22-q11.23UniSTS
Cytogenetic Map10q23UniSTS
Cytogenetic Map17p11.2UniSTS
Cytogenetic Map11p11.2UniSTS
Cytogenetic Map4q21.22UniSTS
Cytogenetic Map13q14.2UniSTS
Cytogenetic Map1q21.2-q21.3UniSTS
Cytogenetic Map9p24.1UniSTS
Cytogenetic Map15q15.3UniSTS
Cytogenetic Map3q13.33UniSTS
Cytogenetic Map8q11.2UniSTS
Cytogenetic MapXq12UniSTS
Cytogenetic Map1q41-q42.2UniSTS
Cytogenetic Map11q22-q23UniSTS
Cytogenetic Map12q23-q24.1UniSTS
Cytogenetic Map1p36.3UniSTS
Cytogenetic Map1p33UniSTS
Cytogenetic Map6p12.3UniSTS
Cytogenetic Map1q43UniSTS
Cytogenetic Map15q26.3UniSTS
Cytogenetic Map15q13.1UniSTS
Cytogenetic MapXq13.1UniSTS
Cytogenetic Map10q11.21UniSTS
Cytogenetic Map17q23.3UniSTS
Cytogenetic Map3p21UniSTS
Cytogenetic Map15q11-q13UniSTS
Cytogenetic Map13q12-q14UniSTS
Cytogenetic Map18q21.1UniSTS
Cytogenetic Map9p23UniSTS
Cytogenetic Map7p12.3UniSTS
Cytogenetic Map3p25.3UniSTS
Cytogenetic Map2q37.2UniSTS
Cytogenetic Map2p14UniSTS
Cytogenetic Map10q11.22UniSTS
Cytogenetic Map1p21.2UniSTS
Cytogenetic Map3p22.1UniSTS
Cytogenetic Map19q13.42UniSTS
Cytogenetic Map19q13.31UniSTS
Cytogenetic Map14q32.2UniSTS
Cytogenetic Map17q21.2UniSTS
Cytogenetic Map13q32.2UniSTS
Cytogenetic Map14q23.1UniSTS
Cytogenetic Map5q11.2UniSTS
Cytogenetic Map2q24.1UniSTS
Cytogenetic Map7q32.1UniSTS
Cytogenetic Map19p13.1UniSTS
Cytogenetic Map5q31.1UniSTS
Cytogenetic Map8p12-p11UniSTS
Cytogenetic Map1q31-q32UniSTS
Cytogenetic Map6q24.1UniSTS
Cytogenetic Map10q24UniSTS
Cytogenetic MapXq28UniSTS
Cytogenetic Map15q26.1UniSTS
Cytogenetic Map10q26.11UniSTS
Cytogenetic Map8p21.1UniSTS
Cytogenetic Map7p15.3UniSTS
Cytogenetic Map7p21.1UniSTS
Cytogenetic Map4q21.1UniSTS
Cytogenetic Map15q11.2UniSTS
Cytogenetic Map13q32.3UniSTS
Cytogenetic MapXq25UniSTS
Cytogenetic Map12q24.33UniSTS
Cytogenetic Map14q23.2UniSTS
Cytogenetic Map2q24.2UniSTS
Cytogenetic Map16p12.2UniSTS
Cytogenetic Map15q21.2UniSTS
Cytogenetic Map3p26.1-p25.1UniSTS
Cytogenetic Map3q13.2UniSTS
Cytogenetic Map4p15.2UniSTS
Cytogenetic Map17q24-q25UniSTS
Cytogenetic Map5q12.1UniSTS
Cytogenetic Map5q15UniSTS
Cytogenetic Map17q22UniSTS
Cytogenetic Map17q21.1UniSTS
Cytogenetic Map8q23.1UniSTS
Cytogenetic Map10p12.31UniSTS
Cytogenetic Map2q33.3UniSTS
Cytogenetic MapXq21UniSTS
Cytogenetic Map6p12UniSTS
Cytogenetic Map2p15-p13UniSTS
Cytogenetic Map19qUniSTS
Cytogenetic Map20p11UniSTS
Cytogenetic Map22q12.3-q13.1UniSTS
Cytogenetic Map1q25.2UniSTS
Cytogenetic Map10q21.3UniSTS
Cytogenetic Map3p21.1-p14.3UniSTS
Cytogenetic Map6p12.1UniSTS
Cytogenetic Map14q23.3UniSTS
Cytogenetic Map4p16.3UniSTS
Cytogenetic Map6q16.1UniSTS
Cytogenetic Map5p13.1UniSTS
Cytogenetic Map9q21.11UniSTS
Cytogenetic Map8q12UniSTS
Cytogenetic Map1q24.2UniSTS
Cytogenetic Map2q34UniSTS
Cytogenetic Map8p11.23UniSTS
Cytogenetic Map14q21.2UniSTS
Cytogenetic Map7q35UniSTS
Cytogenetic Map5p13.3UniSTS
Cytogenetic Map1q42.3UniSTS
Cytogenetic Map1q22-q23UniSTS
Cytogenetic Map6p21.31UniSTS
Cytogenetic Map4q21UniSTS
Cytogenetic Map10p13UniSTS
Cytogenetic Map5q13UniSTS
Cytogenetic Map4q13.3UniSTS
Cytogenetic Map9q34.1UniSTS
Cytogenetic Map5q13.2UniSTS
Cytogenetic Map17p12UniSTS
Cytogenetic Map9q22.1-q22.2UniSTS
Cytogenetic Map18q12.1UniSTS
Cytogenetic Map13q14.11UniSTS
Cytogenetic Map7q21.2UniSTS
Cytogenetic Map9p22.3UniSTS
Cytogenetic Map8q21.11UniSTS
Cytogenetic Map6p22.3UniSTS
Cytogenetic Map5q32UniSTS
Cytogenetic Map4p12UniSTS
Cytogenetic Map2q13UniSTS
Cytogenetic Map21q11.2UniSTS
Cytogenetic Map1p34.1UniSTS
Cytogenetic Map19q11UniSTS
Cytogenetic Map8p21.2UniSTS
Cytogenetic Map15q26.2UniSTS
Cytogenetic Map14q22.1UniSTS
Cytogenetic Map11p15.1UniSTS
Cytogenetic Map10q25.3UniSTS
Cytogenetic Map20q11.23UniSTS
Cytogenetic Map12q13.11UniSTS
Cytogenetic Map11q13.2UniSTS
Cytogenetic Map5p13.2UniSTS
Cytogenetic Map16q24.1UniSTS
Cytogenetic Map9q32UniSTS
Cytogenetic Map2q36.1UniSTS
Cytogenetic Map1q42.13UniSTS
Cytogenetic Map1q21.1UniSTS
Cytogenetic Map17q21.32UniSTS
Cytogenetic Map16q23.1UniSTS
Cytogenetic Map3q25.1UniSTS
Cytogenetic Map1p22.2UniSTS
Cytogenetic Map1p32.2-p32.1UniSTS
Cytogenetic Map15q24UniSTS
Cytogenetic MapXp21.1UniSTS
Cytogenetic Map12q14.3UniSTS
Cytogenetic Map7q36UniSTS
Cytogenetic Map9q34UniSTS
Cytogenetic Map11q22UniSTS
Cytogenetic Map5p15.3UniSTS
Cytogenetic Map7q11.21UniSTS
Cytogenetic Map20q13.3-qterUniSTS
Cytogenetic Map13q13.1UniSTS
Cytogenetic Map1p33-p32UniSTS
Cytogenetic Map21q22.2UniSTS
Cytogenetic Map3q13.13-q13.2UniSTS
Cytogenetic Map3p21.3UniSTS
Cytogenetic Map12p11.21UniSTS
Cytogenetic Map7qUniSTS
Cytogenetic Map11q13.5UniSTS
Cytogenetic Map4q32UniSTS
Cytogenetic Map9q22.33UniSTS
Cytogenetic Map5q35.1UniSTS
Cytogenetic Map9p13.3UniSTS
Cytogenetic Map13q14.13UniSTS
Cytogenetic Map10p12.1UniSTS
Cytogenetic Map20q13.33UniSTS
Cytogenetic Map19p13.13UniSTS
Cytogenetic Map4q13.2UniSTS
Cytogenetic Map4q31.23UniSTS
Cytogenetic Map7q36.3UniSTS
Cytogenetic Map14q24.2UniSTS
RH12587  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3716,525,184 - 6,525,574UniSTSGRCh37
Celera15,639,632 - 5,640,022UniSTS
Cytogenetic Map1p36.2UniSTS
HuRef15,672,727 - 5,673,117UniSTS
GeneMap99-GB4 RH Map125.38UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:5636
Count of miRNA genes:920
Interacting mature miRNAs:1100
Transcripts:ENST00000348333, ENST00000351748, ENST00000351959, ENST00000356876, ENST00000377782, ENST00000414040, ENST00000453260, ENST00000453341, ENST00000461703, ENST00000469691, ENST00000473343, ENST00000475730, ENST00000480393, ENST00000481401, ENST00000485036, ENST00000502588, ENST00000502730, ENST00000510563, ENST00000513135, ENST00000515145
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 1225 1088 964 148 873 36 2476 560 2696 113 1095 997 123 815 1374 1
Low 1208 1881 751 468 608 421 1845 1626 1010 281 352 604 48 389 1405 3 1
Below cutoff 3 15 7 6 345 6 32 7 4 24 1 7 1 9

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_029910 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001039664 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_003790 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_148965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_148966 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_148967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_148970 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB051850 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB051851 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB308321 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF026070 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF026071 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK094463 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL158217 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY254324 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY358309 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC117189 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC143886 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM666370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471130 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CS001236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U72763 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U74611 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U75380 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U75381 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U78029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U83597 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U83598 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U83599 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U83600 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U94501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U94502 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U94503 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U94504 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U94505 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U94506 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U94507 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U94508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U94509 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U94510 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U94512 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y09392 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000348333   ⟹   ENSP00000314451
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl16,461,434 - 6,466,107 (-)Ensembl
RefSeq Acc Id: ENST00000351748   ⟹   ENSP00000326762
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl16,461,434 - 6,466,107 (-)Ensembl
RefSeq Acc Id: ENST00000351959   ⟹   ENSP00000337713
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl16,461,204 - 6,466,175 (-)Ensembl
RefSeq Acc Id: ENST00000356876   ⟹   ENSP00000349341
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl16,461,151 - 6,466,195 (-)Ensembl
RefSeq Acc Id: ENST00000377782   ⟹   ENSP00000367013
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl16,461,151 - 6,466,175 (-)Ensembl
RefSeq Acc Id: ENST00000414040   ⟹   ENSP00000404274
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl16,461,434 - 6,466,107 (-)Ensembl
RefSeq Acc Id: ENST00000453260
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl16,461,480 - 6,463,347 (-)Ensembl
RefSeq Acc Id: ENST00000453341
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl16,464,111 - 6,466,099 (-)Ensembl
RefSeq Acc Id: ENST00000461703
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl16,463,536 - 6,466,107 (-)Ensembl
RefSeq Acc Id: ENST00000469691
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl16,461,994 - 6,465,272 (-)Ensembl
RefSeq Acc Id: ENST00000473343
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl16,461,151 - 6,463,622 (-)Ensembl
RefSeq Acc Id: ENST00000475730
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl16,461,756 - 6,462,607 (-)Ensembl
RefSeq Acc Id: ENST00000480393   ⟹   ENSP00000434129
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl16,461,151 - 6,466,175 (-)Ensembl
RefSeq Acc Id: ENST00000481401   ⟹   ENSP00000465381
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl16,462,637 - 6,465,630 (-)Ensembl
RefSeq Acc Id: ENST00000485036   ⟹   ENSP00000431554
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl16,461,151 - 6,466,175 (-)Ensembl
RefSeq Acc Id: ENST00000502588   ⟹   ENSP00000423121
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl16,461,434 - 6,466,107 (-)Ensembl
RefSeq Acc Id: ENST00000502730   ⟹   ENSP00000421976
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl16,461,434 - 6,466,107 (-)Ensembl
RefSeq Acc Id: ENST00000510563   ⟹   ENSP00000424071
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl16,461,434 - 6,466,107 (-)Ensembl
RefSeq Acc Id: ENST00000513135
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl16,461,151 - 6,466,099 (-)Ensembl
RefSeq Acc Id: ENST00000515145
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl16,464,567 - 6,465,858 (-)Ensembl
RefSeq Acc Id: ENST00000647810   ⟹   ENSP00000497258
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl16,460,786 - 6,465,470 (-)Ensembl
RefSeq Acc Id: NM_001039664   ⟹   NP_001034753
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3816,464,111 - 6,466,173 (-)NCBI
GRCh3716,520,787 - 6,527,432 (-)NCBI
Build 3616,446,758 - 6,448,842 (-)NCBI Archive
HuRef15,668,754 - 5,673,798 (-)ENTREZGENE
CHM1_116,512,684 - 6,514,768 (-)NCBI
Sequence:
RefSeq Acc Id: NM_003790   ⟹   NP_003781
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3816,460,786 - 6,466,173 (-)NCBI
GRCh3716,520,787 - 6,527,432 (-)NCBI
Build 3616,443,798 - 6,448,842 (-)NCBI Archive
HuRef15,668,754 - 5,673,798 (-)ENTREZGENE
CHM1_116,509,749 - 6,514,768 (-)NCBI
Sequence:
RefSeq Acc Id: NM_148965   ⟹   NP_683866
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3816,460,786 - 6,466,173 (-)NCBI
GRCh3716,520,787 - 6,527,432 (-)NCBI
Build 3616,443,798 - 6,448,842 (-)NCBI Archive
HuRef15,668,754 - 5,673,798 (-)ENTREZGENE
CHM1_116,509,749 - 6,514,768 (-)NCBI
Sequence:
RefSeq Acc Id: NM_148966   ⟹   NP_683867
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3816,460,786 - 6,466,173 (-)NCBI
GRCh3716,520,787 - 6,527,432 (-)NCBI
Build 3616,443,798 - 6,448,842 (-)NCBI Archive
HuRef15,668,754 - 5,673,798 (-)ENTREZGENE
CHM1_116,509,749 - 6,514,768 (-)NCBI
Sequence:
RefSeq Acc Id: NM_148967   ⟹   NP_683868
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3816,460,786 - 6,466,173 (-)NCBI
GRCh3716,520,787 - 6,527,432 (-)NCBI
Build 3616,443,798 - 6,448,842 (-)NCBI Archive
HuRef15,668,754 - 5,673,798 (-)ENTREZGENE
CHM1_116,509,749 - 6,514,768 (-)NCBI
Sequence:
RefSeq Acc Id: NM_148970   ⟹   NP_683871
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3816,460,786 - 6,466,173 (-)NCBI
GRCh3716,520,787 - 6,527,432 (-)NCBI
Build 3616,443,798 - 6,448,842 (-)NCBI Archive
HuRef15,668,754 - 5,673,798 (-)ENTREZGENE
CHM1_116,509,749 - 6,514,768 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001034753 (Get FASTA)   NCBI Sequence Viewer  
  NP_003781 (Get FASTA)   NCBI Sequence Viewer  
  NP_683866 (Get FASTA)   NCBI Sequence Viewer  
  NP_683867 (Get FASTA)   NCBI Sequence Viewer  
  NP_683868 (Get FASTA)   NCBI Sequence Viewer  
  NP_683871 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB39714 (Get FASTA)   NCBI Sequence Viewer  
  AAB40918 (Get FASTA)   NCBI Sequence Viewer  
  AAB41432 (Get FASTA)   NCBI Sequence Viewer  
  AAB41433 (Get FASTA)   NCBI Sequence Viewer  
  AAB41434 (Get FASTA)   NCBI Sequence Viewer  
  AAB41435 (Get FASTA)   NCBI Sequence Viewer  
  AAB82288 (Get FASTA)   NCBI Sequence Viewer  
  AAC39556 (Get FASTA)   NCBI Sequence Viewer  
  AAC50819 (Get FASTA)   NCBI Sequence Viewer  
  AAC51192 (Get FASTA)   NCBI Sequence Viewer  
  AAC51193 (Get FASTA)   NCBI Sequence Viewer  
  AAC51306 (Get FASTA)   NCBI Sequence Viewer  
  AAC51307 (Get FASTA)   NCBI Sequence Viewer  
  AAC51308 (Get FASTA)   NCBI Sequence Viewer  
  AAC51309 (Get FASTA)   NCBI Sequence Viewer  
  AAC51310 (Get FASTA)   NCBI Sequence Viewer  
  AAC51311 (Get FASTA)   NCBI Sequence Viewer  
  AAC51312 (Get FASTA)   NCBI Sequence Viewer  
  AAC51313 (Get FASTA)   NCBI Sequence Viewer  
  AAC51314 (Get FASTA)   NCBI Sequence Viewer  
  AAC51315 (Get FASTA)   NCBI Sequence Viewer  
  AAC51316 (Get FASTA)   NCBI Sequence Viewer  
  AAI17190 (Get FASTA)   NCBI Sequence Viewer  
  AAI43887 (Get FASTA)   NCBI Sequence Viewer  
  AAO63495 (Get FASTA)   NCBI Sequence Viewer  
  AAQ88676 (Get FASTA)   NCBI Sequence Viewer  
  BAB40662 (Get FASTA)   NCBI Sequence Viewer  
  BAB40663 (Get FASTA)   NCBI Sequence Viewer  
  BAF64192 (Get FASTA)   NCBI Sequence Viewer  
  BAG52869 (Get FASTA)   NCBI Sequence Viewer  
  CAA70559 (Get FASTA)   NCBI Sequence Viewer  
  CAA70560 (Get FASTA)   NCBI Sequence Viewer  
  CAA70561 (Get FASTA)   NCBI Sequence Viewer  
  CAI48017 (Get FASTA)   NCBI Sequence Viewer  
  EAW71540 (Get FASTA)   NCBI Sequence Viewer  
  EAW71541 (Get FASTA)   NCBI Sequence Viewer  
  EAW71542 (Get FASTA)   NCBI Sequence Viewer  
  EAW71543 (Get FASTA)   NCBI Sequence Viewer  
  EAW71544 (Get FASTA)   NCBI Sequence Viewer  
  EAW71545 (Get FASTA)   NCBI Sequence Viewer  
  EAW71546 (Get FASTA)   NCBI Sequence Viewer  
  EAW71547 (Get FASTA)   NCBI Sequence Viewer  
  EAW71548 (Get FASTA)   NCBI Sequence Viewer  
  EAW71549 (Get FASTA)   NCBI Sequence Viewer  
  Q93038 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_683871   ⟸   NM_148970
- Peptide Label: isoform 7 precursor
- UniProtKB: Q93038 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_683868   ⟸   NM_148967
- Peptide Label: isoform 4 precursor
- UniProtKB: Q93038 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_683867   ⟸   NM_148966
- Peptide Label: isoform 3 precursor
- UniProtKB: Q93038 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_003781   ⟸   NM_003790
- Peptide Label: isoform 2 precursor
- UniProtKB: Q93038 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_683866   ⟸   NM_148965
- Peptide Label: isoform 1 precursor
- UniProtKB: Q93038 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001034753   ⟸   NM_001039664
- Peptide Label: isoform 12 precursor
- UniProtKB: Q93038 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000423121   ⟸   ENST00000502588
RefSeq Acc Id: ENSP00000421976   ⟸   ENST00000502730
RefSeq Acc Id: ENSP00000314451   ⟸   ENST00000348333
RefSeq Acc Id: ENSP00000404274   ⟸   ENST00000414040
RefSeq Acc Id: ENSP00000434129   ⟸   ENST00000480393
RefSeq Acc Id: ENSP00000465381   ⟸   ENST00000481401
RefSeq Acc Id: ENSP00000367013   ⟸   ENST00000377782
RefSeq Acc Id: ENSP00000337713   ⟸   ENST00000351959
RefSeq Acc Id: ENSP00000326762   ⟸   ENST00000351748
RefSeq Acc Id: ENSP00000424071   ⟸   ENST00000510563
RefSeq Acc Id: ENSP00000431554   ⟸   ENST00000485036
RefSeq Acc Id: ENSP00000349341   ⟸   ENST00000356876
RefSeq Acc Id: ENSP00000497258   ⟸   ENST00000647810
Protein Domains
Death   TNFR-Cys

Promoters
RGD ID:6787037
Promoter ID:HG_KWN:438
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell_12Hour
Transcripts:OTTHUMT00000002265,   OTTHUMT00000002268,   OTTHUMT00000002269
Position:
Human AssemblyChrPosition (strand)Source
Build 3616,445,226 - 6,445,726 (-)MPROMDB
RGD ID:6787039
Promoter ID:HG_KWN:439
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour
Transcripts:ENST00000348333,   ENST00000351748,   ENST00000351959,   ENST00000355862,   ENST00000356876,   ENST00000377782,   NM_001039664,   OTTHUMT00000002260,   OTTHUMT00000002261,   OTTHUMT00000002266,   OTTHUMT00000002267,   OTTHUMT00000099349,   UC001ANB.1,   UC001ANC.1,   UC001AND.1,   UC009VLZ.1
Position:
Human AssemblyChrPosition (strand)Source
Build 3616,448,474 - 6,448,974 (-)MPROMDB
RGD ID:6853924
Promoter ID:EPDNEW_H127
Type:initiation region
Name:TNFRSF25_1
Description:TNF receptor superfamily member 25
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H128  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh3816,466,152 - 6,466,212EPDNEW
RGD ID:6853926
Promoter ID:EPDNEW_H128
Type:initiation region
Name:TNFRSF25_2
Description:TNF receptor superfamily member 25
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H127  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh3816,469,123 - 6,469,183EPDNEW

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 1p36.32-36.23(chr1:2844760-8007940)x1 copy number loss See cases [RCV000051086] Chr1:2844760..8007940 [GRCh38]
Chr1:2761325..8068000 [GRCh37]
Chr1:2751185..7990587 [NCBI36]
Chr1:1p36.32-36.23
pathogenic
GRCh38/hg38 1p36.33-36.31(chr1:844347-6477436)x1 copy number loss See cases [RCV000051143] Chr1:844347..6477436 [GRCh38]
Chr1:779727..6537496 [GRCh37]
Chr1:769590..6460083 [NCBI36]
Chr1:1p36.33-36.31
pathogenic
GRCh38/hg38 1p36.33-36.23(chr1:859215-8747647)x1 copy number loss See cases [RCV000052045] Chr1:859215..8747647 [GRCh38]
Chr1:794595..8807706 [GRCh37]
Chr1:784458..8730293 [NCBI36]
Chr1:1p36.33-36.23
pathogenic
GRCh38/hg38 1p36.33-36.23(chr1:629025-8537745)x1 copy number loss See cases [RCV000051993] Chr1:629025..8537745 [GRCh38]
Chr1:564405..8597804 [GRCh37]
Chr1:554268..8520391 [NCBI36]
Chr1:1p36.33-36.23
pathogenic
GRCh38/hg38 1p36.33-36.31(chr1:629044-7008678)x1 copy number loss See cases [RCV000051995] Chr1:629044..7008678 [GRCh38]
Chr1:564424..7068738 [GRCh37]
Chr1:554287..6991325 [NCBI36]
Chr1:1p36.33-36.31
pathogenic
GRCh38/hg38 1p36.33-36.22(chr1:844347-10809098)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052038]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052038]|See cases [RCV000052038] Chr1:844347..10809098 [GRCh38]
Chr1:779727..10869155 [GRCh37]
Chr1:769590..10791742 [NCBI36]
Chr1:1p36.33-36.22
pathogenic
GRCh38/hg38 1p36.33-36.23(chr1:844347-7151129)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052042]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052042]|See cases [RCV000052042] Chr1:844347..7151129 [GRCh38]
Chr1:779727..7211189 [GRCh37]
Chr1:769590..7133776 [NCBI36]
Chr1:1p36.33-36.23
pathogenic
GRCh38/hg38 1p36.32-36.22(chr1:5274008-9329925)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053727]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053727]|See cases [RCV000053727] Chr1:5274008..9329925 [GRCh38]
Chr1:5334068..9389984 [GRCh37]
Chr1:5233928..9312571 [NCBI36]
Chr1:1p36.32-36.22
pathogenic
GRCh38/hg38 1p36.31-36.22(chr1:5682528-10863843)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053730]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053730]|See cases [RCV000053730] Chr1:5682528..10863843 [GRCh38]
Chr1:5742588..10923900 [GRCh37]
Chr1:5665175..10846487 [NCBI36]
Chr1:1p36.31-36.22
pathogenic
GRCh38/hg38 1p36.32-36.21(chr1:2963330-12666744)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053713]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053713]|See cases [RCV000053713] Chr1:2963330..12666744 [GRCh38]
Chr1:2879895..12726755 [GRCh37]
Chr1:2869755..12649342 [NCBI36]
Chr1:1p36.32-36.21
pathogenic
GRCh38/hg38 1p36.32-36.13(chr1:3006193-17688934)x1 copy number loss See cases [RCV000053714] Chr1:3006193..17688934 [GRCh38]
Chr1:2922757..18015429 [GRCh37]
Chr1:2912617..17888016 [NCBI36]
Chr1:1p36.32-36.13
pathogenic
GRCh38/hg38 1p36.32-36.22(chr1:3319336-11243395)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053716]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053716]|See cases [RCV000053716] Chr1:3319336..11243395 [GRCh38]
Chr1:3235900..11303452 [GRCh37]
Chr1:3225760..11226039 [NCBI36]
Chr1:1p36.32-36.22
pathogenic
GRCh38/hg38 1p36.32-36.23(chr1:3438149-8171914)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053718]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053718]|See cases [RCV000053718] Chr1:3438149..8171914 [GRCh38]
Chr1:3354713..8231974 [GRCh37]
Chr1:3344573..8154561 [NCBI36]
Chr1:1p36.32-36.23
pathogenic
GRCh38/hg38 1p36.32-36.23(chr1:3472163-7842947)x1 copy number loss See cases [RCV000053720] Chr1:3472163..7842947 [GRCh38]
Chr1:3388727..7903007 [GRCh37]
Chr1:3378587..7825594 [NCBI36]
Chr1:1p36.32-36.23
pathogenic
GRCh38/hg38 1p36.32-36.21(chr1:4898439-13111056)x1 copy number loss See cases [RCV000053724] Chr1:4898439..13111056 [GRCh38]
Chr1:4958499..13178528 [GRCh37]
Chr1:4858359..13101115 [NCBI36]
Chr1:1p36.32-36.21
pathogenic
NM_020631.4(PLEKHG5):c.1769G>A (p.Ser590Asn) single nucleotide variant Malignant melanoma [RCV000064862] Chr1:6470267 [GRCh38]
Chr1:6530327 [GRCh37]
Chr1:6452914 [NCBI36]
Chr1:1p36.31
not provided
GRCh38/hg38 1p36.33-36.31(chr1:844347-6916587)x1 copy number loss See cases [RCV000133943] Chr1:844347..6916587 [GRCh38]
Chr1:779727..6976647 [GRCh37]
Chr1:769590..6899234 [NCBI36]
Chr1:1p36.33-36.31
pathogenic
GRCh38/hg38 1p36.33-36.23(chr1:844347-8171914)x1 copy number loss See cases [RCV000136554] Chr1:844347..8171914 [GRCh38]
Chr1:779727..8231974 [GRCh37]
Chr1:769590..8154561 [NCBI36]
Chr1:1p36.33-36.23
pathogenic
GRCh38/hg38 1p36.33-36.22(chr1:844347-12470133)x1 copy number loss See cases [RCV000136695] Chr1:844347..12470133 [GRCh38]
Chr1:779727..12530188 [GRCh37]
Chr1:769590..12452775 [NCBI36]
Chr1:1p36.33-36.22
pathogenic|likely pathogenic
GRCh38/hg38 1p36.32-36.21(chr1:4898439-12911913)x1 copy number loss See cases [RCV000137461] Chr1:4898439..12911913 [GRCh38]
Chr1:4958499..12971757 [GRCh37]
Chr1:4858359..12894344 [NCBI36]
Chr1:1p36.32-36.21
pathogenic
GRCh38/hg38 1p36.31-36.21(chr1:6303641-15799093)x1 copy number loss See cases [RCV000137948] Chr1:6303641..15799093 [GRCh38]
Chr1:6363701..16125588 [GRCh37]
Chr1:6286288..15998175 [NCBI36]
Chr1:1p36.31-36.21
pathogenic|likely benign
GRCh38/hg38 1p36.33-36.31(chr1:844353-6477474)x1 copy number loss See cases [RCV000139404] Chr1:844353..6477474 [GRCh38]
Chr1:779733..6537534 [GRCh37]
Chr1:769596..6460121 [NCBI36]
Chr1:1p36.33-36.31
pathogenic
GRCh38/hg38 1p36.33-36.31(chr1:821713-7000838)x1 copy number loss See cases [RCV000138896] Chr1:821713..7000838 [GRCh38]
Chr1:757093..7060898 [GRCh37]
Chr1:746956..6983485 [NCBI36]
Chr1:1p36.33-36.31
pathogenic
GRCh38/hg38 1p36.33-36.22(chr1:914086-9567122)x1 copy number loss See cases [RCV000141970] Chr1:914086..9567122 [GRCh38]
Chr1:849466..9627180 [GRCh37]
Chr1:839329..9549767 [NCBI36]
Chr1:1p36.33-36.22
pathogenic
GRCh38/hg38 1p36.32-36.23(chr1:2868477-7332569)x1 copy number loss See cases [RCV000141437] Chr1:2868477..7332569 [GRCh38]
Chr1:2785042..7392629 [GRCh37]
Chr1:2774902..7315216 [NCBI36]
Chr1:1p36.32-36.23
pathogenic
GRCh38/hg38 1p36.33-36.22(chr1:902111-9556305)x1 copy number loss See cases [RCV000141577] Chr1:902111..9556305 [GRCh38]
Chr1:837491..9616363 [GRCh37]
Chr1:827354..9538950 [NCBI36]
Chr1:1p36.33-36.22
pathogenic
GRCh38/hg38 1p36.33-36.23(chr1:898721-7811306)x1 copy number loss See cases [RCV000142651] Chr1:898721..7811306 [GRCh38]
Chr1:834101..7871366 [GRCh37]
Chr1:823964..7793953 [NCBI36]
Chr1:1p36.33-36.23
pathogenic
GRCh38/hg38 1p36.33-36.22(chr1:911300-9329925)x1 copy number loss See cases [RCV000142615] Chr1:911300..9329925 [GRCh38]
Chr1:846680..9389984 [GRCh37]
Chr1:836543..9312571 [NCBI36]
Chr1:1p36.33-36.22
pathogenic
GRCh38/hg38 1p36.33-36.23(chr1:844347-7870545)x1 copy number loss See cases [RCV000142709] Chr1:844347..7870545 [GRCh38]
Chr1:779727..7930605 [GRCh37]
Chr1:769590..7853192 [NCBI36]
Chr1:1p36.33-36.23
pathogenic
GRCh38/hg38 1p36.31-36.13(chr1:5363826-18360302)x1 copy number loss See cases [RCV000142771] Chr1:5363826..18360302 [GRCh38]
Chr1:5423886..18686796 [GRCh37]
Chr1:5323746..18559383 [NCBI36]
Chr1:1p36.31-36.13
pathogenic
Single allele complex Ductal breast carcinoma [RCV000207058] Chr1:909238..24706269 [GRCh37]
Chr1:1p36.33-36.11
uncertain significance
chr1:909238-16736132 complex variant complex Ductal breast carcinoma [RCV000207094] Chr1:909238..16736132 [GRCh37]
Chr1:1p36.33-36.13
uncertain significance
GRCh37/hg19 1p36.33-36.22(chr1:82154-12699337)x1 copy number loss See cases [RCV000239416] Chr1:82154..12699337 [GRCh37]
Chr1:1p36.33-36.22
pathogenic
GRCh37/hg19 1p36.33-36.21(chr1:746608-15077159)x1 copy number loss See cases [RCV000240403] Chr1:746608..15077159 [GRCh37]
Chr1:1p36.33-36.21
pathogenic
NM_020631.5(PLEKHG5):c.*1440C>T single nucleotide variant Distal spinal muscular atrophy, autosomal recessive 4 [RCV000399468] Chr1:6466123 [GRCh38]
Chr1:6526183 [GRCh37]
Chr1:1p36.31
benign
NM_003790.2(TNFRSF25):c.-43_-36del deletion Distal spinal muscular atrophy [RCV000302421] Chr1:6466143..6466150 [GRCh38]
Chr1:6526203..6526210 [GRCh37]
Chr1:1p36.31
benign
GRCh37/hg19 1p36.32-36.22(chr1:2817420-10670878)x1 copy number loss See cases [RCV000449468] Chr1:2817420..10670878 [GRCh37]
Chr1:1p36.32-36.22
pathogenic
GRCh37/hg19 1p36.33-36.31(chr1:849466-6566086)x1 copy number loss See cases [RCV000449148] Chr1:849466..6566086 [GRCh37]
Chr1:1p36.33-36.31
pathogenic
GRCh37/hg19 1p36.33-36.22(chr1:849466-9683808)x1 copy number loss See cases [RCV000446331] Chr1:849466..9683808 [GRCh37]
Chr1:1p36.33-36.22
pathogenic
GRCh37/hg19 1p36.32-36.21(chr1:4558588-13187457)x1 copy number loss See cases [RCV000446359] Chr1:4558588..13187457 [GRCh37]
Chr1:1p36.32-36.21
pathogenic
GRCh37/hg19 1p36.32-36.12(chr1:2749920-22564787)x1 copy number loss See cases [RCV000446470] Chr1:2749920..22564787 [GRCh37]
Chr1:1p36.32-36.12
pathogenic
GRCh37/hg19 1p36.32-36.31(chr1:2609223-2631378)x3 copy number gain See cases [RCV000447158] Chr1:2609223..2631378 [GRCh37]
Chr1:1p36.32-36.31
benign
GRCh37/hg19 1p36.33-36.23(chr1:849466-7300178)x1 copy number loss See cases [RCV000448061] Chr1:849466..7300178 [GRCh37]
Chr1:1p36.33-36.23
pathogenic
GRCh37/hg19 1p36.32-36.23(chr1:2793822-7510850)x1 copy number loss See cases [RCV000510212] Chr1:2793822..7510850 [GRCh37]
Chr1:1p36.32-36.23
pathogenic
GRCh37/hg19 1p36.33-q44(chr1:849467-249224684)x3 copy number gain See cases [RCV000510383] Chr1:849467..249224684 [GRCh37]
Chr1:1p36.33-q44
pathogenic
GRCh37/hg19 1p36.33-36.23(chr1:849466-7637060)x1 copy number loss See cases [RCV000511381] Chr1:849466..7637060 [GRCh37]
Chr1:1p36.33-36.23
pathogenic
GRCh37/hg19 1p36.33-q44(chr1:849467-249224684) copy number gain See cases [RCV000510926] Chr1:849467..249224684 [GRCh37]
Chr1:1p36.33-q44
pathogenic
GRCh37/hg19 1p36.33-36.23(chr1:849466-8901938)x1 copy number loss See cases [RCV000512568] Chr1:849466..8901938 [GRCh37]
Chr1:1p36.33-36.23
pathogenic
GRCh37/hg19 1p36.33-36.23(chr1:849466-7305595)x1 copy number loss not provided [RCV000684534] Chr1:849466..7305595 [GRCh37]
Chr1:1p36.33-36.23
pathogenic
GRCh37/hg19 1p36.33-q44(chr1:47851-249228449)x3 copy number gain not provided [RCV000736295] Chr1:47851..249228449 [GRCh37]
Chr1:1p36.33-q44
pathogenic
GRCh37/hg19 1p36.33-q44(chr1:82154-249218992)x3 copy number gain not provided [RCV000736305] Chr1:82154..249218992 [GRCh37]
Chr1:1p36.33-q44
pathogenic
GRCh37/hg19 1p36.33-36.31(chr1:47851-6659872)x1 copy number loss not provided [RCV000736294] Chr1:47851..6659872 [GRCh37]
Chr1:1p36.33-36.31
pathogenic
GRCh37/hg19 1p36.31(chr1:6279370-6568387)x3 copy number gain not provided [RCV000736369] Chr1:6279370..6568387 [GRCh37]
Chr1:1p36.31
benign
GRCh37/hg19 1p36.33-36.23(chr1:82154-7936272)x1 copy number loss not provided [RCV000736304] Chr1:82154..7936272 [GRCh37]
Chr1:1p36.33-36.23
pathogenic
GRCh37/hg19 1p36.31(chr1:6456472-6560363)x3 copy number gain not provided [RCV000736376] Chr1:6456472..6560363 [GRCh37]
Chr1:1p36.31
benign
GRCh37/hg19 1p36.31(chr1:6481916-6560363)x3 copy number gain not provided [RCV000736377] Chr1:6481916..6560363 [GRCh37]
Chr1:1p36.31
benign
GRCh37/hg19 1p36.32-36.23(chr1:4965631-8106987)x1 copy number loss not provided [RCV000736366] Chr1:4965631..8106987 [GRCh37]
Chr1:1p36.32-36.23
pathogenic
GRCh37/hg19 1p36.31(chr1:6501100-6568387)x1 copy number loss not provided [RCV000748865] Chr1:6501100..6568387 [GRCh37]
Chr1:1p36.31
benign
GRCh37/hg19 1p36.31(chr1:6523430-6534226)x3 copy number gain not provided [RCV000748866] Chr1:6523430..6534226 [GRCh37]
Chr1:1p36.31
benign
GRCh37/hg19 1p36.31(chr1:6523430-6534600)x3 copy number gain not provided [RCV000748867] Chr1:6523430..6534600 [GRCh37]
Chr1:1p36.31
benign
GRCh37/hg19 1p36.31(chr1:6523430-6560363)x3 copy number gain not provided [RCV000748868] Chr1:6523430..6560363 [GRCh37]
Chr1:1p36.31
benign
NM_148965.1(TNFRSF25):c.772-10T>C single nucleotide variant not provided [RCV000972358] Chr1:6462184 [GRCh38]
Chr1:6522244 [GRCh37]
Chr1:1p36.31
likely benign
GRCh37/hg19 1p36.33-36.31(chr1:823964-6828363) copy number loss Chromosome 1p36 deletion syndrome [RCV000767774] Chr1:823964..6828363 [GRCh37]
Chr1:1p36.33-36.31
pathogenic
GRCh37/hg19 1p36.33-36.22(chr1:82154-11784118)x1 copy number loss See cases [RCV000790592] Chr1:82154..11784118 [GRCh37]
Chr1:1p36.33-36.22
pathogenic
GRCh37/hg19 1p36.33-36.23(chr1:82154-7637060)x1 copy number loss See cases [RCV000790584] Chr1:82154..7637060 [GRCh37]
Chr1:1p36.33-36.23
pathogenic
NM_148965.1(TNFRSF25):c.426A>G (p.Leu142=) single nucleotide variant not provided [RCV000958403] Chr1:6464589 [GRCh38]
Chr1:6524649 [GRCh37]
Chr1:1p36.31
benign
Single allele deletion Neurodevelopmental disorder [RCV000787413] Chr1:554375..9779842 [GRCh37]
Chr1:1p36.33-36.22
pathogenic
GRCh37/hg19 1p36.33-36.23(chr1:849466-7786545)x1 copy number loss not provided [RCV001005057] Chr1:849466..7786545 [GRCh37]
Chr1:1p36.33-36.23
pathogenic
NM_148965.1(TNFRSF25):c.798C>T (p.Ser266=) single nucleotide variant not provided [RCV000892331] Chr1:6462148 [GRCh38]
Chr1:6522208 [GRCh37]
Chr1:1p36.31
benign
NM_003790.3(TNFRSF25):c.-51A>G single nucleotide variant Distal spinal muscular atrophy, autosomal recessive 4 [RCV001097872] Chr1:6466158 [GRCh38]
Chr1:6526218 [GRCh37]
Chr1:1p36.31
uncertain significance
GRCh37/hg19 1p36.33-36.23(chr1:762080-7309686) copy number loss Harel-Yoon syndrome [RCV001254115] Chr1:762080..7309686 [GRCh37]
Chr1:1p36.33-36.23
likely pathogenic

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:11910 AgrOrtholog
COSMIC TNFRSF25 COSMIC
Ensembl Genes ENSG00000215788 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000314451 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000326762 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000337713 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000349341 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000367013 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000404274 UniProtKB/Swiss-Prot
  ENSP00000421976 UniProtKB/Swiss-Prot
  ENSP00000423121 UniProtKB/Swiss-Prot
  ENSP00000424071 UniProtKB/Swiss-Prot
  ENSP00000431554 UniProtKB/Swiss-Prot
  ENSP00000434129 UniProtKB/TrEMBL
  ENSP00000465381 UniProtKB/TrEMBL
  ENSP00000497258 UniProtKB/TrEMBL
Ensembl Transcript ENST00000348333 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000351748 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000351959 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000356876 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000377782 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000414040 UniProtKB/Swiss-Prot
  ENST00000453341 ENTREZGENE
  ENST00000480393 UniProtKB/TrEMBL
  ENST00000481401 UniProtKB/TrEMBL
  ENST00000485036 UniProtKB/Swiss-Prot
  ENST00000502588 UniProtKB/Swiss-Prot
  ENST00000502730 UniProtKB/Swiss-Prot
  ENST00000510563 UniProtKB/Swiss-Prot
  ENST00000647810 UniProtKB/TrEMBL
GTEx ENSG00000215788 GTEx
HGNC ID HGNC:11910 ENTREZGENE
Human Proteome Map TNFRSF25 Human Proteome Map
InterPro DEATH-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Death_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TNFR/NGFR_Cys_rich_reg UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TNFR_25 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TNFRSF25_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:8718 UniProtKB/Swiss-Prot
NCBI Gene 8718 ENTREZGENE
OMIM 603366 OMIM
PANTHER PTHR47220 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Death UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TNFR_c6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA36603 PharmGKB
PRINTS TNFACTORR25 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE DEATH_DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TNFR_NGFR_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TNFR_NGFR_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART DEATH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TNFR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47986 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0C4DGF3_HUMAN UniProtKB/TrEMBL
  A0A3B3ISD9_HUMAN UniProtKB/TrEMBL
  A5LIN1_HUMAN UniProtKB/TrEMBL
  K7EJY9_HUMAN UniProtKB/TrEMBL
  Q93038 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary B1ALX2 UniProtKB/Swiss-Prot
  B1ALX3 UniProtKB/Swiss-Prot
  B7ZLL7 UniProtKB/Swiss-Prot
  O00275 UniProtKB/Swiss-Prot
  O00276 UniProtKB/Swiss-Prot
  O00277 UniProtKB/Swiss-Prot
  O00278 UniProtKB/Swiss-Prot
  O00279 UniProtKB/Swiss-Prot
  O00280 UniProtKB/Swiss-Prot
  O14865 UniProtKB/Swiss-Prot
  O14866 UniProtKB/Swiss-Prot
  P78507 UniProtKB/Swiss-Prot
  P78515 UniProtKB/Swiss-Prot
  Q17RU4 UniProtKB/Swiss-Prot
  Q92983 UniProtKB/Swiss-Prot
  Q93036 UniProtKB/Swiss-Prot
  Q93037 UniProtKB/Swiss-Prot
  Q99722 UniProtKB/Swiss-Prot
  Q99830 UniProtKB/Swiss-Prot
  Q99831 UniProtKB/Swiss-Prot
  Q9BY86 UniProtKB/Swiss-Prot
  Q9UME0 UniProtKB/Swiss-Prot
  Q9UME1 UniProtKB/Swiss-Prot
  Q9UME5 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-06-30 TNFRSF25  TNF receptor superfamily member 25    tumor necrosis factor receptor superfamily member 25  Symbol and/or name change 5135510 APPROVED
2015-11-24 TNFRSF25  tumor necrosis factor receptor superfamily member 25    tumor necrosis factor receptor superfamily, member 25  Symbol and/or name change 5135510 APPROVED
2011-08-16 TNFRSF25  tumor necrosis factor receptor superfamily, member 25  TNFRSF25  tumor necrosis factor receptor superfamily, member 25  Symbol and/or name change 5135510 APPROVED