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motexafin gadolinium - Ontology Report - Rat Genome Database

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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:motexafin gadolinium
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Accession:CHEBI:50161 term browser browse the term
Definition:A metallotexaphyrin that has formula C52H72GdN5O14.
Synonyms:exact_synonym: bis(acetato-kappaO){3,3'-[4,5-diethyl-16,17-bis{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}-10,23-dimethyl-13,20,25,26,27-pentaazapentacyclo[20.2.1.1(3,6).1(8,11).0(14,19)]heptacosa-1,3,5,7,9,11(26),12,14,16,18,20,22(25),23-tridecaene-9,24-diyl-kappa(5)N(13),N(20),N(25),N(26),N(27)]dipropan-1-olato}gadolinium
 related_synonym: (PB-7-11-233'2'4)-bis(acetato-kappaO)(9,10-diethyl-20,21-bis(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)-4,15-dimethyl-8,11-imino-3,6:16,13-dinitrilo-1,18-benzodiazacycloeicosine-5,14-dipropanolato-kappaN(1),kappaN(18),kappaN(23),kappaN(24),kappaN(25))gadolinium;   Formula=C52H72GdN5O14;   Gd texaphyrin;   Gd-Tex;   InChI=1S/C48H66N5O10.2C2H4O2.Gd/c1-7-35-36(8-2)40-28-42-38(12-10-14-55)34(4)46(53-42)32-50-44-30-48(63-26-24-61-22-20-59-18-16-57-6)47(62-25-23-60-21-19-58-17-15-56-5)29-43(44)49-31-45-33(3)37(11-9-13-54)41(52-45)27-39(35)51-40;2*1-2(3)4;/h27-32,54-55H,7-26H2,1-6H3;2*1H3,(H,3,4);/q-1;;;+3/p-2/b39-27-,40-28-,41-27-,42-28-,45-31-,46-32-,49-31+,49-43+,50-32+,50-44+;;;;   InChIKey=VAZLWPAHMORDGR-WRIGXHCHSA-L;   MGd;   SMILES=CCc1c(CC)c2C=C3C(CCCO)=C(C)C4=[N]3[Gd]356(OC(C)=O)(OC(C)=O)[N](=CC7=[N]3C(=Cc1n25)C(CCCO)=C7C)c1cc(OCCOCCOCCOC)c(OCCOCCOCCOC)cc1[N]6=C4;   Xcytrin;   gadolinium texaphyrin
 xref: Beilstein:10643305;   CAS:246252-06-2;   Gmelin:1458776;   Gmelin:1760576
 xref_mesh: MESH:C437683
 xref: PMID:17112739;   Patent:US2005159401

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motexafin gadolinium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agl amylo-alpha-1,6-glucosidase and 4-alpha-glucanotransferase multiple interactions
decreases expression		 ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of AGL mRNA
motexafin gadolinium results in decreased expression of AGL mRNA		 CTD PMID:16357179 NCBI chr 2:207,389,949...207,445,959
Ensembl chr 2:204,705,053...204,760,828 		JBrowse link
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 multiple interactions
increases expression		 ISO motexafin gadolinium inhibits the reaction [Zinc Acetate results in increased expression of ALDH5A1 mRNA]
motexafin gadolinium results in increased expression of ALDH5A1 mRNA		 CTD PMID:16357179 NCBI chr17:40,560,373...40,586,711
Ensembl chr17:40,130,883...40,158,677 		JBrowse link
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 decreases expression
multiple interactions		 ISO motexafin gadolinium results in decreased expression of ALDH6A1 mRNA
Zinc Acetate inhibits the reaction [motexafin gadolinium results in decreased expression of ALDH6A1 mRNA]		 CTD PMID:16357179 NCBI chr 6:104,077,975...104,098,636
Ensembl chr 6:104,077,979...104,098,656 		JBrowse link
G Arhgap17 Rho GTPase activating protein 17 decreases expression
multiple interactions		 ISO motexafin gadolinium results in decreased expression of ARHGAP17 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of ARHGAP17 mRNA		 CTD PMID:16357179 NCBI chr 1:187,238,675...187,328,093
Ensembl chr 1:177,807,583...177,896,854 		JBrowse link
G Atf3 activating transcription factor 3 multiple interactions
increases expression		 ISO motexafin gadolinium promotes the reaction [Zinc Acetate results in increased expression of ATF3 mRNA]
motexafin gadolinium results in increased expression of ATF3 mRNA		 CTD PMID:16357179 NCBI chr13:105,274,103...105,331,653
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Atm ATM serine/threonine kinase multiple interactions
increases expression		 ISO motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of ATM mRNA]
motexafin gadolinium results in increased expression of ATM mRNA		 CTD PMID:16357179 NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Atr ATR serine/threonine kinase decreases expression
multiple interactions		 ISO motexafin gadolinium results in decreased expression of ATR mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of ATR mRNA		 CTD PMID:16357179 NCBI chr 8:105,306,299...105,403,742
Ensembl chr 8:96,426,724...96,524,136 		JBrowse link
G Bach1 BTB domain and CNC homolog 1 increases expression
multiple interactions		 ISO motexafin gadolinium results in increased expression of BACH1 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of BACH1 mRNA		 CTD PMID:16357179 NCBI chr11:40,425,721...40,461,118
Ensembl chr11:26,939,480...26,972,447 		JBrowse link
G Bag3 BAG cochaperone 3 multiple interactions
increases expression		 ISO motexafin gadolinium promotes the reaction [Zinc Acetate results in increased expression of BAG3 mRNA]
motexafin gadolinium results in increased expression of BAG3 mRNA		 CTD PMID:16357179 NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858 		JBrowse link
G Bbc3 Bcl-2 binding component 3 multiple interactions ISO [Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of BBC3 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of BBC3 protein] CTD PMID:20530418 NCBI chr 1:86,141,450...86,150,666
Ensembl chr 1:77,014,543...77,022,509 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions
increases expression		 ISO motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of BIRC5 mRNA]
motexafin gadolinium results in increased expression of BIRC5 mRNA		 CTD PMID:16357179 NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Bnip3 BCL2 interacting protein 3 increases expression
multiple interactions		 ISO motexafin gadolinium results in increased expression of BNIP3 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of BNIP3 mRNA		 CTD PMID:16357179 NCBI chr 1:203,137,778...203,154,962
Ensembl chr 1:193,708,167...193,725,359 		JBrowse link
G Bnip3l BCL2 interacting protein 3 like increases expression
multiple interactions		 ISO motexafin gadolinium results in increased expression of BNIP3L mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of BNIP3L mRNA		 CTD PMID:16357179 NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803 		JBrowse link
G Canx calnexin increases expression
multiple interactions		 ISO motexafin gadolinium results in increased expression of CANX mRNA
[Zinc Acetate co-treated with motexafin gadolinium] affects the expression of CANX mRNA		 CTD PMID:16357179 NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821 		JBrowse link
G Casp3 caspase 3 decreases expression
multiple interactions		 ISO motexafin gadolinium results in decreased expression of CASP3 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CASP3 mRNA		 CTD PMID:16357179 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cbfb core-binding factor subunit beta increases expression
multiple interactions		 ISO motexafin gadolinium results in increased expression of CBFB mRNA
[Zinc Acetate co-treated with motexafin gadolinium] affects the expression of CBFB mRNA		 CTD PMID:16357179 NCBI chr19:33,049,162...33,092,752
Ensembl chr19:33,049,172...33,092,751 		JBrowse link
G Ccnj cyclin J multiple interactions
decreases expression		 ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CCNJ mRNA
motexafin gadolinium results in decreased expression of CCNJ mRNA		 CTD PMID:16357179 NCBI chr 1:239,659,588...239,677,367 JBrowse link
G Cdc16 cell division cycle 16 decreases expression
multiple interactions		 ISO motexafin gadolinium results in decreased expression of CDC16 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CDC16 mRNA		 CTD PMID:16357179 NCBI chr16:82,475,234...82,498,797
Ensembl chr16:75,773,028...75,796,550 		JBrowse link
G Cdc25c cell division cycle 25C increases expression
multiple interactions		 ISO motexafin gadolinium results in increased expression of CDC25C mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of CDC25C mRNA		 CTD PMID:16357179 NCBI chr18:26,608,483...26,630,292
Ensembl chr18:26,335,834...26,356,185 		JBrowse link
G Cdc27 cell division cycle 27 increases expression
multiple interactions		 ISO motexafin gadolinium results in increased expression of CDC27 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] affects the expression of CDC27 mRNA		 CTD PMID:16357179 NCBI chr10:89,400,720...89,449,816
Ensembl chr10:89,400,940...89,449,736 		JBrowse link
G Cdc5l cell division cycle 5-like decreases expression
multiple interactions		 ISO motexafin gadolinium results in decreased expression of CDC5L mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CDC5L mRNA		 CTD PMID:16357179 NCBI chr 9:23,062,397...23,100,901
Ensembl chr 9:15,564,767...15,603,450 		JBrowse link
G Cdca2 cell division cycle associated 2 decreases expression
multiple interactions		 ISO motexafin gadolinium results in decreased expression of CDCA2 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CDCA2 mRNA		 CTD PMID:16357179 NCBI chr15:41,895,946...41,942,226
Ensembl chr15:41,895,901...41,941,611 		JBrowse link
G Cdk19 cyclin-dependent kinase 19 increases expression ISO motexafin gadolinium results in increased expression of CDK19 mRNA CTD PMID:16357179 NCBI chr20:43,770,409...43,910,629
Ensembl chr20:43,770,409...43,910,628 		JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions
increases expression		 ISO motexafin gadolinium inhibits the reaction [Zinc Acetate results in increased expression of CDK2 mRNA]
motexafin gadolinium results in increased expression of CDK2 mRNA		 CTD PMID:16357179 NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,129,811...1,137,403 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO [Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CDKN1A mRNA; nutlin 3 inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CDKN1A mRNA] CTD PMID:20530418 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression
multiple interactions		 ISO motexafin gadolinium results in increased expression of CDKN1B mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of CDKN1B mRNA		 CTD PMID:16357179 NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cth cystathionine gamma-lyase increases expression
multiple interactions		 ISO motexafin gadolinium results in increased expression of CTH mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of CTH mRNA		 CTD PMID:16357179 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234 		JBrowse link
G Cul3 cullin 3 decreases expression
multiple interactions		 ISO motexafin gadolinium results in decreased expression of CUL3 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CUL3 mRNA		 CTD PMID:16357179 NCBI chr 9:81,592,641...81,670,428
Ensembl chr 9:81,592,641...81,670,462 		JBrowse link
G Cyb5r1 cytochrome b5 reductase 1 multiple interactions
increases expression		 ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of CYB5R1 mRNA
motexafin gadolinium results in increased expression of CYB5R1 mRNA		 CTD PMID:16357179 NCBI chr13:45,849,017...45,855,458
Ensembl chr13:45,849,091...45,855,458 		JBrowse link
G Dapk3 death-associated protein kinase 3 multiple interactions
decreases expression		 ISO motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of DAPK3 mRNA]
motexafin gadolinium results in decreased expression of DAPK3 mRNA		 CTD PMID:16357179 NCBI chr 7:9,174,903...9,183,272
Ensembl chr 7:8,524,183...8,532,558 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression		 ISO motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of DDIT3 mRNA]
motexafin gadolinium results in increased expression of DDIT3 mRNA		 CTD PMID:16357179 NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression
multiple interactions		 ISO motexafin gadolinium results in increased expression of DDIT4 mRNA
motexafin gadolinium promotes the reaction [Zinc Acetate results in increased expression of DDIT4 mRNA]; Zinc Acetate promotes the reaction [motexafin gadolinium results in increased expression of DDIT4 mRNA]		 CTD PMID:16357179 NCBI chr20:28,434,938...28,437,037
Ensembl chr20:27,891,998...27,894,105 		JBrowse link
G Dedd2 death effector domain containing 2 multiple interactions
increases expression		 ISO motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of DEDD2 mRNA]
motexafin gadolinium results in increased expression of DEDD2 mRNA		 CTD PMID:16357179 NCBI chr 1:89,916,906...89,934,663
Ensembl chr 1:80,792,000...80,807,714 		JBrowse link
G Dffb DNA fragmentation factor subunit beta decreases expression
multiple interactions		 ISO motexafin gadolinium results in decreased expression of DFFB mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of DFFB mRNA		 CTD PMID:16357179 NCBI chr 5:164,522,446...164,534,733
Ensembl chr 5:164,522,463...164,534,628 		JBrowse link
G Dhcr7 7-dehydrocholesterol reductase decreases expression ISO motexafin gadolinium results in decreased expression of DHCR7 mRNA CTD PMID:16357179 NCBI chr 1:208,444,434...208,460,408
Ensembl chr 1:199,015,081...199,031,055 		JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 multiple interactions
increases expression		 ISO motexafin gadolinium inhibits the reaction [Zinc Acetate results in decreased expression of DNAJB1 mRNA]
motexafin gadolinium results in increased expression of DNAJB1 mRNA		 CTD PMID:16357179 NCBI chr19:41,427,453...41,431,141
Ensembl chr19:24,522,717...24,526,458 		JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 increases expression
multiple interactions		 ISO motexafin gadolinium results in increased expression of DNAJB4 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of DNAJB4 mRNA		 CTD PMID:16357179 NCBI chr 2:243,790,296...243,819,042
Ensembl chr 2:241,130,340...241,159,089 		JBrowse link
G Dnajb6 DnaJ heat shock protein family (Hsp40) member B6 increases expression
multiple interactions		 ISO motexafin gadolinium results in increased expression of DNAJB6 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of DNAJB6 mRNA		 CTD PMID:16357179 NCBI chr 4:6,010,081...6,232,052
Ensembl chr 4:5,452,683...5,556,659 		JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 multiple interactions
increases expression		 ISO motexafin gadolinium inhibits the reaction [Zinc Acetate results in increased expression of DNAJC3 mRNA]
motexafin gadolinium results in increased expression of DNAJC3 mRNA		 CTD PMID:16357179 NCBI chr15:102,432,667...102,475,643
Ensembl chr15:96,025,624...96,065,181 		JBrowse link
G E2f1 E2F transcription factor 1 multiple interactions
increases expression		 ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of E2F1 mRNA
motexafin gadolinium results in increased expression of E2F1 mRNA		 CTD PMID:16357179 NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361 		JBrowse link
G E2f3 E2F transcription factor 3 increases expression
multiple interactions		 ISO motexafin gadolinium results in increased expression of E2F3 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of E2F3 mRNA		 CTD PMID:16357179 NCBI chr17:34,601,756...34,679,139
Ensembl chr17:34,601,830...34,676,253 		JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 increases expression
multiple interactions		 ISO motexafin gadolinium results in increased expression of EGLN1 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of EGLN1 mRNA		 CTD PMID:16357179 NCBI chr19:52,867,900...52,907,308
Ensembl chr19:52,869,486...52,907,777 		JBrowse link
G Elp1 elongator acetyltransferase complex subunit 1 decreases expression
multiple interactions		 ISO motexafin gadolinium results in decreased expression of ELP1 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of ELP1 mRNA		 CTD PMID:16357179 NCBI chr 5:71,453,338...71,505,833
Ensembl chr 5:71,456,310...71,505,762 		JBrowse link
G Eno1 enolase 1 increases expression ISO motexafin gadolinium results in increased expression of ENO1 mRNA CTD PMID:16357179 NCBI chr 5:166,002,867...166,014,252
Ensembl chr 5:160,719,951...160,731,336
Ensembl chr 3:160,719,951...160,731,336 		JBrowse link
G Fadd Fas associated via death domain decreases expression
multiple interactions		 ISO motexafin gadolinium results in decreased expression of FADD mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of FADD mRNA		 CTD PMID:16357179 NCBI chr 1:209,169,245...209,175,423
Ensembl chr 1:199,739,994...199,745,653 		JBrowse link
G Faim Fas apoptotic inhibitory molecule decreases expression
multiple interactions		 ISO motexafin gadolinium results in decreased expression of FAIM mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of FAIM mRNA		 CTD PMID:16357179 NCBI chr 8:99,543,877...99,569,499
Ensembl chr 8:99,542,405...99,560,562 		JBrowse link
G Fam162a family with sequence similarity 162, member A increases expression
multiple interactions		 ISO motexafin gadolinium results in increased expression of FAM162A mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of FAM162A mRNA		 CTD PMID:16357179 NCBI chr11:64,680,978...64,709,865
Ensembl chr11:64,680,323...64,711,239 		JBrowse link
G Fasn fatty acid synthase decreases expression ISO motexafin gadolinium results in decreased expression of FASN mRNA CTD PMID:16357179 NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G Foxo3 forkhead box O3 increases expression
multiple interactions		 ISO motexafin gadolinium results in increased expression of FOXO3 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of FOXO3 mRNA		 CTD PMID:16357179 NCBI chr20:47,251,968...47,348,254
Ensembl chr20:45,672,995...45,764,561 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions
increases expression		 ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of GCLM mRNA
motexafin gadolinium results in increased expression of GCLM mRNA		 CTD PMID:16357179 NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Gls glutaminase decreases expression
multiple interactions		 ISO motexafin gadolinium results in decreased expression of GLS mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of GLS mRNA		 CTD PMID:16357179 NCBI chr 9:49,344,616...49,416,900
Ensembl chr 9:49,344,781...49,416,900 		JBrowse link
G Gpr146 G protein-coupled receptor 146 increases expression ISO motexafin gadolinium results in increased expression of GPR146 mRNA CTD PMID:16357179 NCBI chr12:15,251,936...15,267,217
Ensembl chr12:15,251,813...15,267,206 		JBrowse link
G Gpt2 glutamic--pyruvic transaminase 2 increases expression ISO motexafin gadolinium results in increased expression of GPT2 mRNA CTD PMID:16357179 NCBI chr19:21,526,800...21,561,314
Ensembl chr19:21,517,621...21,560,610 		JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions ISO [Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of GPX1 mRNA; nutlin 3 inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of GPX1 mRNA] CTD PMID:20530418 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Gsr glutathione-disulfide reductase increases expression
multiple interactions		 ISO motexafin gadolinium results in increased expression of GSR mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of GSR mRNA		 CTD PMID:16357179 NCBI chr16:65,185,574...65,228,742
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Gtf3c2 general transcription factor IIIC subunit 2 increases expression ISO motexafin gadolinium results in increased expression of GTF3C2 mRNA CTD PMID:16357179 NCBI chr 6:30,913,263...30,941,305
Ensembl chr 6:25,197,268...25,220,490 		JBrowse link
G Hbp1 HMG-box transcription factor 1 multiple interactions
increases expression		 ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of HBP1 mRNA
motexafin gadolinium results in increased expression of HBP1 mRNA		 CTD PMID:16357179 NCBI chr 6:54,257,118...54,283,373
Ensembl chr 6:48,529,372...48,555,787 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions
increases expression		 ISO [motexafin gadolinium co-treated with Zinc Acetate] results in increased expression of HIF1A protein
motexafin gadolinium results in increased expression of HIF1A protein		 CTD PMID:16357179 NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hilpda hypoxia inducible lipid droplet-associated increases expression
multiple interactions		 ISO motexafin gadolinium results in increased expression of HILPDA mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of HILPDA mRNA		 CTD PMID:16357179 NCBI chr 4:57,871,088...57,874,048
Ensembl chr 4:57,871,110...57,874,557 		JBrowse link
G Hipk1 homeodomain interacting protein kinase 1 multiple interactions
increases expression		 ISO motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of HIPK1 mRNA]
motexafin gadolinium results in increased expression of HIPK1 mRNA		 CTD PMID:16357179 NCBI chr 2:193,937,261...193,988,247
Ensembl chr 2:191,248,817...191,298,902 		JBrowse link
G Hltf helicase-like transcription factor multiple interactions
decreases expression		 ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of HLTF mRNA
motexafin gadolinium results in decreased expression of HLTF mRNA		 CTD PMID:16357179 NCBI chr 2:102,549,724...102,609,492
Ensembl chr 2:102,549,724...102,609,327 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression		 ISO [motexafin gadolinium co-treated with Zinc Acetate] results in increased expression of HMOX1 protein; motexafin gadolinium promotes the reaction [Zinc Acetate results in increased expression of HMOX1 mRNA]
motexafin gadolinium results in increased expression of HMOX1 mRNA		 CTD PMID:16357179 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hrk harakiri, BCL2 interacting protein multiple interactions
increases expression		 ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of HRK mRNA
motexafin gadolinium results in increased expression of HRK mRNA		 CTD PMID:16357179 NCBI chr12:44,048,402...44,070,561 JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 multiple interactions
increases expression		 ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of HSP90AB1 mRNA
motexafin gadolinium results in increased expression of HSP90AB1 mRNA		 CTD PMID:16357179 NCBI chr 9:22,930,249...22,935,929
Ensembl chr 9:15,433,691...15,438,488 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A multiple interactions
increases expression		 ISO motexafin gadolinium promotes the reaction [Zinc Acetate results in increased expression of HSPA1A mRNA]; Zinc Acetate promotes the reaction [motexafin gadolinium results in increased expression of HSPA1A mRNA] CTD PMID:16357179 NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,856,006...3,873,227 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B multiple interactions
increases expression		 ISO motexafin gadolinium promotes the reaction [Zinc Acetate results in increased expression of HSPA1B mRNA]; Zinc Acetate promotes the reaction [motexafin gadolinium results in increased expression of HSPA1B mRNA] CTD PMID:16357179 NCBI chr20:3,859,756...3,863,800
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 increases expression
multiple interactions		 ISO motexafin gadolinium results in increased expression of HSPA4 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of HSPA4 mRNA		 CTD PMID:16357179 NCBI chr10:37,908,866...37,951,994
Ensembl chr10:37,408,025...37,449,001 		JBrowse link
G Hspa4l heat shock protein family A (Hsp70) member 4 like increases expression
multiple interactions		 ISO motexafin gadolinium results in increased expression of HSPA4L mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of HSPA4L mRNA		 CTD PMID:16357179 NCBI chr 2:123,740,384...123,793,088
Ensembl chr 2:123,740,384...123,793,084 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 multiple interactions
increases expression		 ISO motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of HSPB1 mRNA]
motexafin gadolinium results in increased expression of HSPB1 mRNA		 CTD PMID:16357179 NCBI chr12:26,430,640...26,432,301
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 multiple interactions
increases expression		 ISO motexafin gadolinium promotes the reaction [Zinc Acetate results in increased expression of HSPD1 mRNA]
motexafin gadolinium results in increased expression of HSPD1 mRNA		 CTD PMID:16357179 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662 		JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 increases expression
multiple interactions		 ISO motexafin gadolinium results in increased expression of HSPH1 mRNA
motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of HSPH1 mRNA]		 CTD PMID:16357179 NCBI chr12:10,427,368...10,446,602
Ensembl chr12:5,390,922...5,410,224 		JBrowse link
G Id2 inhibitor of DNA binding 2 increases expression
multiple interactions		 ISO motexafin gadolinium results in increased expression of ID2 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of ID2 mRNA		 CTD PMID:16357179 NCBI chr 6:47,469,162...47,470,995
Ensembl chr 6:41,728,946...41,744,400 		JBrowse link
G Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon increases expression
multiple interactions		 ISO motexafin gadolinium results in increased expression of IKBKE mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of IKBKE mRNA		 CTD PMID:16357179 NCBI chr13:42,712,154...42,738,470
Ensembl chr13:42,712,159...42,737,143 		JBrowse link
G Irf2bp2 interferon regulatory factor 2 binding protein 2 increases expression
multiple interactions		 ISO motexafin gadolinium results in increased expression of IRF2BP2 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of IRF2BP2 mRNA		 CTD PMID:16357179 NCBI chr19:54,559,417...54,565,096
Ensembl chr19:54,560,128...54,566,642 		JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions		 ISO motexafin gadolinium results in increased expression of JUND mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of JUND mRNA		 CTD PMID:16357179 NCBI chr16:18,768,093...18,769,771
Ensembl chr16:18,734,122...18,735,799 		JBrowse link
G Kdm3a lysine demethylase 3A increases expression ISO motexafin gadolinium results in increased expression of KDM3A mRNA CTD PMID:16357179 NCBI chr 4:103,630,907...103,675,073
Ensembl chr 4:103,630,908...103,675,073 		JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression
multiple interactions		 ISO motexafin gadolinium results in increased expression of MDM2 mRNA
motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of MDM2 mRNA]		 CTD PMID:16357179 NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Mob1a MOB kinase activator 1A increases expression
multiple interactions		 ISO motexafin gadolinium results in increased expression of MOB1A mRNA
motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of MOB1A mRNA]		 CTD PMID:16357179 NCBI chr 4:115,831,581...115,848,561
Ensembl chr 4:115,831,551...115,848,561
Ensembl chr 1:115,831,551...115,848,561 		JBrowse link
G Mt1 metallothionein 1 multiple interactions ISO [Zinc co-treated with motexafin gadolinium] results in increased expression of MT1A mRNA CTD PMID:15867382 NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049
Ensembl chr  X:10,826,032...10,827,049 		JBrowse link
G Mt1-ps3 metallothionein 1, pseudogene 3 multiple interactions
increases expression		 ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of MT1E mRNA
motexafin gadolinium results in increased expression of MT1E mRNA		 CTD PMID:15867382 PMID:16357179 NCBI chr17:74,786,652...74,787,040
Ensembl chr17:74,786,654...74,787,135 		JBrowse link
G Mt2 metallothionein 2 multiple interactions
increases expression		 ISO motexafin gadolinium promotes the reaction [Zinc Acetate results in increased expression of MT2A mRNA]
motexafin gadolinium results in increased expression of MT2A mRNA		 CTD PMID:15867382 PMID:16357179 NCBI chr19:10,837,934...10,838,708
Ensembl chr19:10,832,002...10,832,784 		JBrowse link
G Mt2-ps1 metallothionein 2, pseudogene 1 multiple interactions
increases expression		 ISO motexafin gadolinium promotes the reaction [Zinc Acetate results in increased expression of MT1HL1 mRNA]
motexafin gadolinium results in increased expression of MT1HL1 mRNA		 CTD PMID:15867382 PMID:16357179 NCBI chr20:3,159,037...3,159,409
Ensembl chr 5:119,728,811...119,730,073 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor multiple interactions
decreases expression		 ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of MYD88 mRNA
motexafin gadolinium results in decreased expression of MYD88 mRNA		 CTD PMID:16357179 NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Nadk NAD kinase increases expression
multiple interactions		 ISO motexafin gadolinium results in increased expression of NADK mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of NADK mRNA		 CTD PMID:16357179 NCBI chr 5:171,427,973...171,458,586
Ensembl chr 5:166,145,481...166,176,322 		JBrowse link
G Nf1 neurofibromin 1 multiple interactions
increases expression		 ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of NF1 mRNA
motexafin gadolinium results in increased expression of NF1 mRNA		 CTD PMID:16357179 NCBI chr10:64,803,986...65,037,086
Ensembl chr10:64,306,301...64,536,658 		JBrowse link
G Nisch nischarin decreases expression ISO motexafin gadolinium results in decreased expression of NISCH mRNA CTD PMID:16357179 NCBI chr16:6,370,809...6,407,104
Ensembl chr16:6,364,374...6,400,668 		JBrowse link
G Nr1d2 nuclear receptor subfamily 1, group D, member 2 increases expression
multiple interactions		 ISO motexafin gadolinium results in increased expression of NR1D2 mRNA
motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of NR1D2 mRNA]		 CTD PMID:16357179 NCBI chr15:7,524,257...7,550,553
Ensembl chr15:7,524,257...7,550,553 		JBrowse link
G P4hb prolyl 4-hydroxylase subunit beta multiple interactions
increases expression		 ISO motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of P4HB mRNA]
motexafin gadolinium results in increased expression of P4HB mRNA		 CTD PMID:16357179 NCBI chr10:106,335,300...106,346,911
Ensembl chr10:105,836,982...105,848,500 		JBrowse link
G Pdcd11 programmed cell death 11 decreases expression ISO motexafin gadolinium results in decreased expression of PDCD11 mRNA CTD PMID:16357179 NCBI chr 1:255,922,198...255,963,336
Ensembl chr 1:245,980,880...246,021,999 		JBrowse link
G Pdcd4 programmed cell death 4 increases expression
multiple interactions		 ISO motexafin gadolinium results in increased expression of PDCD4 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of PDCD4 mRNA		 CTD PMID:16357179 NCBI chr 1:262,912,659...262,949,581
Ensembl chr 1:252,921,392...252,944,275 		JBrowse link
G Pdcd5 programmed cell death 5 decreases expression
multiple interactions		 ISO motexafin gadolinium results in decreased expression of PDCD5 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of PDCD5 mRNA		 CTD PMID:16357179 NCBI chr 1:97,442,755...97,448,084
Ensembl chr 1:88,305,869...88,311,200 		JBrowse link
G Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 increases expression
multiple interactions		 ISO motexafin gadolinium results in increased expression of PFKFB3 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of PFKFB3 mRNA		 CTD PMID:16357179 NCBI chr17:71,893,320...71,974,526
Ensembl chr17:66,983,686...67,063,125 		JBrowse link
G Pfkfb4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 increases expression
multiple interactions		 ISO motexafin gadolinium results in increased expression of PFKFB4 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of PFKFB4 mRNA		 CTD PMID:16357179 NCBI chr 8:118,522,371...118,565,478
Ensembl chr 8:109,643,937...109,685,634 		JBrowse link
G Pgk1 phosphoglycerate kinase 1 increases expression
multiple interactions		 ISO motexafin gadolinium results in increased expression of PGK1 mRNA
motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of PGK1 mRNA]		 CTD PMID:16357179 NCBI chr  X:75,336,988...75,352,962
Ensembl chr  X:71,271,440...71,287,418 		JBrowse link
G Phtf2 putative homeodomain transcription factor 2 multiple interactions
increases expression		 ISO motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of PHTF2 mRNA]
motexafin gadolinium results in increased expression of PHTF2 mRNA		 CTD PMID:16357179 NCBI chr 4:14,215,190...14,330,549
Ensembl chr 4:14,215,263...14,330,513 		JBrowse link
G Pias1 protein inhibitor of activated STAT, 1 multiple interactions
increases expression		 ISO motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of PIAS1 mRNA]
motexafin gadolinium results in increased expression of PIAS1 mRNA		 CTD PMID:16357179 NCBI chr 8:72,233,566...72,347,085
Ensembl chr 8:63,338,150...63,438,905 		JBrowse link
G Pik3ip1 phosphoinositide-3-kinase interacting protein 1 increases expression
multiple interactions		 ISO motexafin gadolinium results in increased expression of PIK3IP1 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of PIK3IP1 mRNA		 CTD PMID:16357179 NCBI chr14:78,204,668...78,216,616
Ensembl chr14:78,204,053...78,216,608 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 multiple interactions
increases expression		 ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of PMAIP1 mRNA
motexafin gadolinium results in increased expression of PMAIP1 mRNA		 CTD PMID:16357179 NCBI chr18:62,255,970...62,262,384
Ensembl chr18:59,986,017...59,992,429 		JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta multiple interactions
increases expression		 ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of PRKACB mRNA
motexafin gadolinium results in increased expression of PRKACB mRNA		 CTD PMID:16357179 NCBI chr 2:238,297,140...238,389,317
Ensembl chr 2:235,636,885...235,726,198 		JBrowse link
G Prkcd protein kinase C, delta decreases expression ISO motexafin gadolinium results in decreased expression of PRKCD mRNA CTD PMID:16357179 NCBI chr16:5,775,681...5,806,122
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
G Prkd2 protein kinase D2 decreases expression ISO motexafin gadolinium results in decreased expression of PRKD2 mRNA CTD PMID:16357179 NCBI chr 1:86,640,095...86,670,476
Ensembl chr 1:77,513,986...77,542,376 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit increases expression ISO motexafin gadolinium results in increased expression of PRKDC mRNA CTD PMID:16357179 NCBI chr11:98,544,952...98,762,499
Ensembl chr11:85,040,792...85,257,952 		JBrowse link
G Ptrh2 peptidyl-tRNA hydrolase 2 decreases expression
multiple interactions		 ISO motexafin gadolinium results in decreased expression of PTRH2 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of PTRH2 mRNA		 CTD PMID:16357179 NCBI chr10:71,505,113...71,515,297
Ensembl chr10:71,504,956...71,515,398 		JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases expression
multiple interactions		 ISO motexafin gadolinium results in decreased expression of RB1 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of RB1 mRNA		 CTD PMID:16357179 NCBI chr15:54,780,858...54,911,989
Ensembl chr15:48,371,296...48,502,302 		JBrowse link
G Rcbtb2 RCC1 and BTB domain containing protein 2 multiple interactions
decreases expression		 ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of RCBTB2 mRNA
motexafin gadolinium results in decreased expression of RCBTB2 mRNA		 CTD PMID:16357179 NCBI chr15:48,319,809...48,364,441
Ensembl chr15:48,323,866...48,383,750 		JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit increases expression
multiple interactions		 ISO motexafin gadolinium results in increased expression of RELB mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of RELB mRNA		 CTD PMID:16357179 NCBI chr 1:88,385,717...88,413,380
Ensembl chr 1:79,257,725...79,285,507 		JBrowse link
G Rnf19b ring finger protein 19B increases expression ISO motexafin gadolinium results in increased expression of RNF19B mRNA CTD PMID:15867382 NCBI chr 5:141,406,085...141,431,376
Ensembl chr 5:141,406,118...141,431,380 		JBrowse link
G Samtor S-adenosylmethionine sensor upstream of mTORC1 multiple interactions
increases expression		 ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of SAMTOR mRNA
motexafin gadolinium results in increased expression of SAMTOR mRNA		 CTD PMID:16357179 NCBI chr 4:41,881,630...41,945,472
Ensembl chr 4:41,879,993...41,945,539 		JBrowse link
G Selenow selenoprotein W multiple interactions
increases expression		 ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of SELENOW mRNA
motexafin gadolinium results in increased expression of SELENOW mRNA		 CTD PMID:16357179 NCBI chr 1:85,727,631...85,732,703
Ensembl chr 1:76,598,779...76,604,724
Ensembl chr 1:76,598,779...76,604,724 		JBrowse link
G Sesn2 sestrin 2 multiple interactions
increases expression		 ISO [Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of SESN2 mRNA; [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of SESN2 mRNA; nutlin 3 inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of SESN2 mRNA]
motexafin gadolinium results in increased expression of SESN2 mRNA		 CTD PMID:16357179 PMID:20530418 NCBI chr 5:149,986,304...150,005,255
Ensembl chr 5:144,701,530...144,721,260 		JBrowse link
G Slc16a1 solute carrier family 16 member 1 multiple interactions
increases expression		 ISO motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of SLC16A1 mRNA]
motexafin gadolinium results in increased expression of SLC16A1 mRNA		 CTD PMID:16357179 NCBI chr 2:194,805,556...194,832,966
Ensembl chr 2:192,124,289...192,144,611 		JBrowse link
G Slc16a6 solute carrier family 16, member 6 multiple interactions
increases expression		 ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of SLC16A6 mRNA
motexafin gadolinium results in increased expression of SLC16A6 mRNA		 CTD PMID:16357179 NCBI chr10:94,424,377...94,447,482
Ensembl chr10:94,426,244...94,448,779 		JBrowse link
G Slc1a4 solute carrier family 1 member 4 multiple interactions
increases expression		 ISO motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of SLC1A4 mRNA]
motexafin gadolinium results in increased expression of SLC1A4 mRNA		 CTD PMID:16357179 NCBI chr14:94,530,801...94,560,190
Ensembl chr14:94,529,084...94,560,418 		JBrowse link
G Slc30a1 solute carrier family 30 member 1 multiple interactions
increases expression		 ISO [Zinc co-treated with motexafin gadolinium] results in increased expression of SLC30A1 mRNA; motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of SLC30A1 mRNA]; Zinc Acetate affects the reaction [motexafin gadolinium results in increased expression of SLC30A1 mRNA] CTD PMID:15867382 PMID:16357179 NCBI chr13:103,491,037...103,494,910
Ensembl chr13:103,491,037...103,494,910 		JBrowse link
G Slc38a2 solute carrier family 38, member 2 multiple interactions
increases expression		 ISO motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of SLC38A2 mRNA]; Zinc Acetate affects the reaction [motexafin gadolinium results in increased expression of SLC38A2 mRNA] CTD PMID:16357179 NCBI chr 7:127,851,267...127,863,482
Ensembl chr 7:127,851,267...127,863,436 		JBrowse link
G Slc39a10 solute carrier family 39 member 10 multiple interactions
affects expression		 ISO [Zinc Acetate co-treated with motexafin gadolinium] affects the expression of SLC39A10 mRNA
motexafin gadolinium affects the expression of SLC39A10 mRNA		 CTD PMID:16357179 NCBI chr 9:54,836,841...54,960,325
Ensembl chr 9:54,876,141...54,960,325 		JBrowse link
G Slc39a14 solute carrier family 39 member 14 increases expression
multiple interactions		 ISO motexafin gadolinium results in increased expression of SLC39A14 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] affects the expression of SLC39A14 mRNA		 CTD PMID:16357179 NCBI chr15:45,376,806...45,423,549
Ensembl chr15:45,376,917...45,423,524 		JBrowse link
G Slc39a9 solute carrier family 39, member 9 increases expression
multiple interactions		 ISO motexafin gadolinium results in increased expression of SLC39A9 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of SLC39A9 mRNA		 CTD PMID:16357179 NCBI chr 6:100,291,537...100,330,419
Ensembl chr 6:100,291,573...100,330,408 		JBrowse link
G Slc3a2 solute carrier family 3 member 2 multiple interactions
increases expression		 ISO [Zinc Acetate co-treated with motexafin gadolinium] affects the expression of SLC3A2 mRNA
motexafin gadolinium results in increased expression of SLC3A2 mRNA		 CTD PMID:16357179 NCBI chr 1:215,033,601...215,048,064
Ensembl chr 1:205,604,468...205,618,931 		JBrowse link
G Slc43a1 solute carrier family 43 member 1 multiple interactions
increases expression		 ISO [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of SLC43A1 mRNA
motexafin gadolinium results in increased expression of SLC43A1 mRNA		 CTD PMID:16357179 NCBI chr 3:69,920,586...69,946,768
Ensembl chr 3:69,920,649...69,946,768 		JBrowse link
G Slc7a1 solute carrier family 7 member 1 multiple interactions
increases expression		 ISO [Zinc Acetate co-treated with motexafin gadolinium] affects the expression of SLC7A1 mRNA
motexafin gadolinium results in increased expression of SLC7A1 mRNA		 CTD PMID:16357179 NCBI chr12:6,628,288...6,703,849
Ensembl chr12:6,628,007...6,703,849 		JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression
multiple interactions		 ISO motexafin gadolinium results in increased expression of SLC7A11 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] affects the expression of SLC7A11 mRNA		 CTD PMID:16357179 NCBI chr 2:136,532,912...136,668,560
Ensembl chr 2:133,963,107...134,517,536 		JBrowse link
G Smarca4 SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4 decreases expression
multiple interactions		 ISO motexafin gadolinium results in decreased expression of SMARCA4 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of SMARCA4 mRNA		 CTD PMID:16357179 NCBI chr 8:28,438,370...28,535,071
Ensembl chr 8:20,167,717...20,258,975 		JBrowse link
G Smarca5 SNF2 related chromatin remodeling ATPase 5 decreases expression
multiple interactions		 ISO motexafin gadolinium results in decreased expression of SMARCA5 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of SMARCA5 mRNA		 CTD PMID:16357179 NCBI chr19:44,172,465...44,208,967
Ensembl chr19:27,271,148...27,304,594 		JBrowse link
G Tagap T-cell activation RhoGTPase activating protein increases expression
multiple interactions		 ISO motexafin gadolinium results in increased expression of TAGAP mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of TAGAP mRNA		 CTD PMID:16357179 NCBI chr 1:47,170,725...47,179,705
Ensembl chr 1:47,170,725...47,179,792 		JBrowse link
G Tfrc transferrin receptor multiple interactions
increases expression		 ISO motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of TFRC mRNA]
motexafin gadolinium results in increased expression of TFRC mRNA		 CTD PMID:16357179 NCBI chr11:81,668,478...81,690,318
Ensembl chr11:68,163,413...68,185,257 		JBrowse link
G Tnfaip8 TNF alpha induced protein 8 decreases expression
multiple interactions		 ISO motexafin gadolinium results in decreased expression of TNFAIP8 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TNFAIP8 mRNA		 CTD PMID:16357179 NCBI chr18:43,183,854...43,299,512
Ensembl chr18:43,183,916...43,299,517 		JBrowse link
G Tnfrsf17 TNF receptor superfamily member 17 multiple interactions
decreases expression		 ISO [Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TNFRSF17 mRNA
motexafin gadolinium results in decreased expression of TNFRSF17 mRNA		 CTD PMID:16357179 NCBI chr10:4,808,023...4,813,857
Ensembl chr10:4,301,038...4,306,788 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A increases expression
multiple interactions		 ISO motexafin gadolinium results in increased expression of TNFRSF1A mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of TNFRSF1A mRNA		 CTD PMID:16357179 NCBI chr 4:159,837,119...159,849,817
Ensembl chr 4:158,150,820...158,163,591 		JBrowse link
G Tnfsf8 TNF superfamily member 8 multiple interactions
increases expression		 ISO motexafin gadolinium inhibits the reaction [Zinc Acetate results in increased expression of TNFSF8 mRNA]
motexafin gadolinium results in increased expression of TNFSF8 mRNA		 CTD PMID:16357179 NCBI chr 5:82,266,436...82,292,858
Ensembl chr 5:77,251,373...77,277,421 		JBrowse link
G Tnip2 TNFAIP3 interacting protein 2 decreases expression ISO motexafin gadolinium results in decreased expression of TNIP2 mRNA CTD PMID:16357179 NCBI chr14:76,228,350...76,245,553
Ensembl chr14:76,228,371...76,275,265 		JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO [Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TP53 protein; Acetylcysteine inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TP53 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TP53 protein]; nutlin 3 inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TP53 protein] CTD PMID:20530418 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Trib3 tribbles pseudokinase 3 increases expression
multiple interactions		 ISO motexafin gadolinium results in increased expression of TRIB3 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of TRIB3 mRNA		 CTD PMID:16357179 NCBI chr 3:161,269,939...161,275,533
Ensembl chr 3:140,809,043...140,814,497 		JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression
multiple interactions		 ISO motexafin gadolinium results in increased expression of TXNRD1 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of TXNRD1 mRNA		 CTD PMID:16357179 NCBI chr 7:22,717,620...22,802,553
Ensembl chr 7:20,830,045...20,907,863 		JBrowse link
G Vegfa vascular endothelial growth factor A increases expression
multiple interactions		 ISO motexafin gadolinium results in increased expression of VEGFA mRNA
[Zinc Acetate co-treated with motexafin gadolinium] affects the expression of VEGFA mRNA		 CTD PMID:16357179 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Vhl von Hippel-Lindau tumor suppressor multiple interactions
increases expression		 ISO motexafin gadolinium inhibits the reaction [Zinc Acetate results in increased expression of VHL mRNA]
motexafin gadolinium results in increased expression of VHL mRNA		 CTD PMID:16357179 NCBI chr 4:146,772,483...146,779,376
Ensembl chr 4:146,772,468...146,779,377 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19887
    chemical entity 19885
      molecular entity 19884
        transition element molecular entity 17466
          f-block molecular entity 413
            lanthanoid molecular entity 413
              lanthanoid coordination entity 320
                gadolinium coordination entity 243
                  motexafin gadolinium 136
                    motexafin gadolinium hydrate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19887
    subatomic particle 19885
      composite particle 19885
        hadron 19885
          baryon 19885
            nucleon 19885
              atomic nucleus 19885
                atom 19885
                  main group element atom 19824
                    p-block element atom 19824
                      carbon group element atom 19763
                        carbon atom 19760
                          organic molecular entity 19760
                            organic molecule 19713
                              organic cyclic compound 19505
                                organic heterocyclic compound 18875
                                  organonitrogen heterocyclic compound 18154
                                    polypyrrole 710
                                      cyclic polypyrrole 584
                                        expanded porphyrin 136
                                          texaphyrin 136
                                            metallotexaphyrin 136
                                              motexafin gadolinium 136
                                                motexafin gadolinium hydrate 0
paths to the root