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Gene: Dedd2 (death effector domain containing 2) Rattus norvegicus
Symbol: Dedd2
Name: death effector domain containing 2
Description: Predicted to have DNA binding activity. Predicted to be involved in apoptotic nuclear changes; extrinsic apoptotic signaling pathway via death domain receptors; and positive regulation of extrinsic apoptotic signaling pathway. Predicted to localize to the nucleolus. Orthologous to human DEDD2 (death effector domain containing 2); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; cobalt dichloride; endosulfan.
Type: protein-coding
RefSeq Status: MODEL
Also known as: DNA-binding death effector domain-containing protein 2; LOC687118; similar to death effector domain-containing DNA binding protein 2
Homo sapiens (human) : DEDD2 (death effector domain containing 2)  HGNC  Alliance
Mus musculus (house mouse) : Dedd2 (death effector domain-containing DNA binding protein 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dedd2 (death effector domain containing 2)
Pan paniscus (bonobo/pygmy chimpanzee) : DEDD2 (death effector domain containing 2)
Canis lupus familiaris (dog) : DEDD2 (death effector domain containing 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dedd2 (death effector domain containing 2)
Sus scrofa (pig) : DEDD2 (death effector domain containing 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0182,073,024 - 82,089,028 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0183,341,497 - 83,357,501 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera175,235,627 - 75,251,267 (-)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Dedd2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1588968
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.