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Gene: Dedd2 (death effector domain containing 2) Rattus norvegicus
Symbol: Dedd2
Name: death effector domain containing 2
RGD ID: 1588968
Description: Predicted to have DNA binding activity. Predicted to be involved in apoptotic nuclear changes; extrinsic apoptotic signaling pathway via death domain receptors; and positive regulation of extrinsic apoptotic signaling pathway. Predicted to localize to nucleolus and nucleoplasm. Orthologous to human DEDD2 (death effector domain containing 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cobalt dichloride.
Type: protein-coding
RefSeq Status: MODEL
Also known as: DNA-binding death effector domain-containing protein 2; LOC687118; similar to death effector domain-containing DNA binding protein 2
Homo sapiens (human) : DEDD2 (death effector domain containing 2)  HGNC  Alliance
Mus musculus (house mouse) : Dedd2 (death effector domain-containing DNA binding protein 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dedd2 (death effector domain containing 2)
Pan paniscus (bonobo/pygmy chimpanzee) : DEDD2 (death effector domain containing 2)
Canis lupus familiaris (dog) : DEDD2 (death effector domain containing 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dedd2 (death effector domain containing 2)
Sus scrofa (pig) : DEDD2 (death effector domain containing 2)
Chlorocebus sabaeus (African green monkey) : DEDD2 (death effector domain containing 2)
Heterocephalus glaber (naked mole-rat) : Dedd2 (death effector domain containing 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0182,073,024 - 82,089,028 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl182,072,544 - 82,088,275 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0183,341,497 - 83,357,501 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera175,235,627 - 75,251,267 (-)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Dedd2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1588968
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.